Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A1BG ENSG00000121410 "Alpha-1-B glycoprotein" P04217 19 58345178-58353492 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1493 "liver: 1224.7" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 1548.5" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;RH-30: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB016673, HPA044252" Supported "Secreted to blood" NA NA 200000000000 51000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016673: AB_1611892, HPA044252: AB_2678876" "unprognostic (9.95e-2)" "unprognostic (5.31e-2)" "unprognostic (3.67e-2)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (1.66e-2)" "prognostic favorable (3.97e-4)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-1)" "unprognostic (1.47e-2)" "unprognostic (1.37e-2)" "unprognostic (4.19e-5)" "unprognostic (2.37e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (6.72e-2)" 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.8 0.1 0.2 0.0 0.0 0.1 1224.7 0.1 0.3 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.6 0.0 2.5 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.0 0.0 0.9 0.3 0.8 0.0 0.1 0.1 0.7 1.3 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.3 0.4 0.0 0.6 0.2 0.0 0.0 0.9 0.9 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 10.2 12.8 14.1 0.7 50.2 8.8 2.2 16.2 12.0 3.4 52.0 64.3 0.7 27.1 10.6 22.0 2.1 1.0 71.2 0.0 7.9 0.9 0.6 5.0 52.6 10.9 1.2 56.2 2.2 9.2 15.6 20.3 5.1 2.1 17.7 10.8 43.2 1548.5 25.1 8.4 1.7 0.1 20.3 110.9 66.0 2.1 1.2 49.4 115.6 0.0 60.8 3.1 15.5 0.0 8.7 5.4 0.0 1.2 94.4 11.1 0.0 2.0 15.0 5.5 26.3 29.2 43.8 4.1 7.9 1.5 3.7 1.9 52.6 0.7 0.2 0.6 A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 A2ML1 "CPAMD9, FLJ25179, p170" ENSG00000166535 "Alpha-2-macroglobulin like 1" A8K2U0 12 8822621-8887001 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 556.3;vagina: 204.8" "Cell type enriched" "Detected in some" 6 "Squamous epithelial cells: 127.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 39.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 10.9;hTCEpi: 5.5;SK-BR-3: 13.9" "Low region specificity" "Detected in many" "HPA038847, HPA038848" Enhanced "Secreted in other tissues" NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038847: AB_2676236, HPA038848: AB_10672654" "unprognostic (1.13e-2)" "unprognostic (7.64e-2)" "unprognostic (1.04e-2)" "unprognostic (9.46e-3)" "unprognostic (2.14e-1)" "unprognostic (5.54e-3)" "unprognostic (4.59e-2)" "unprognostic (7.58e-3)" "unprognostic (2.63e-1)" "unprognostic (1.57e-1)" "unprognostic (1.15e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-9)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (5.88e-2)" "unprognostic (2.42e-2)" 0.2 0.1 2.1 0.0 2.1 0.2 4.1 0.8 2.4 116.5 0.6 0.1 0.0 0.5 0.4 556.3 0.7 0.2 0.4 2.0 2.2 0.1 0.3 0.1 0.2 1.8 3.1 0.4 0.2 0.8 1.4 0.7 1.3 0.6 0.0 0.7 99.0 0.0 0.3 72.0 0.1 0.1 1.7 0.1 0.7 5.0 4.3 3.0 0.1 0.0 51.5 1.1 204.8 1.5 0.1 0.0 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.2 0.0 2.5 10.9 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 13.9 0.0 1.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 2.1 2.1 0.8 2.4 2.0 2.2 1.8 3.1 1.3 1.7 4.3 1.5 0.0 0.0 0.0 20.2 0.0 0.4 0.5 1.0 1.8 0.7 0.3 0.1 0.7 0.0 2.2 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.4 4.4 0.9 0.3 0.0 0.0 4.9 0.0 0.5 0.4 0.0 11.9 0.0 0.8 0.0 0.0 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.0 0.0 0.0 1.2 0.0 2.0 0.5 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.3 0.0 0.4 0.3 1.0 0.4 127.6 12.6 0.1 0.1 1.9 0.0 8.2 AADACL2 MGC72001 ENSG00000197953 "Arylacetamide deacetylase like 2" Q6P093 3 151733916-151761339 "Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "skin 1: 35.6" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 30.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.20e-2)" "unprognostic (3.10e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (3.00e-1)" "unprognostic (2.91e-4)" 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 35.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 30.7 0.1 0.1 0.0 0.0 0.0 ABHD15 ENSG00000168792 "Abhydrolase domain containing 15" Q6UXT9 17 29560547-29567037 "Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 26.2" "Cell type enhanced" "Detected in many" "dendritic cells: 79.4;Hepatocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;MAIT T-cell: 6.6;NK-cell: 10.8;plasmacytoid DC: 23.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA014470 Approved Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA014470: AB_1852993" "unprognostic (1.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.38e-1)" "unprognostic (8.60e-3)" "unprognostic (1.91e-1)" "unprognostic (1.62e-1)" "unprognostic (4.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.85e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-3)" "unprognostic (3.00e-2)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (1.71e-1)" "unprognostic (3.46e-1)" "unprognostic (5.45e-2)" 19.2 3.8 3.6 6.2 4.0 8.2 10.6 3.8 3.3 4.6 3.8 7.3 11.2 4.5 3.3 4.7 4.7 5.2 4.9 3.1 4.1 8.9 26.2 6.0 9.1 4.9 4.2 2.9 8.1 7.9 9.1 4.5 4.7 4.7 6.5 1.6 5.1 3.8 2.6 4.6 11.2 4.0 4.2 9.9 8.3 1.8 4.3 4.6 5.8 3.8 8.1 5.6 4.6 4.9 5.8 22.1 2.7 7.7 29.0 12.6 11.3 7.8 8.6 7.6 6.9 5.1 2.9 8.6 5.6 8.4 13.4 15.6 9.7 3.3 4.2 26.5 7.3 3.5 11.0 6.5 8.8 9.0 15.4 9.4 8.9 7.3 1.4 5.6 5.6 5.0 4.6 8.0 4.1 7.8 8.5 10.4 0.6 19.5 6.5 19.7 10.5 20.0 13.7 8.8 1.9 3.1 11.7 5.2 3.1 2.9 13.2 20.5 6.9 4.4 5.5 11.1 7.0 13.3 9.6 4.4 8.8 5.6 9.6 18.3 0.6 2.8 2.6 0.3 6.6 1.4 1.4 2.2 1.5 2.5 0.4 1.3 0.6 10.8 0.2 23.6 1.2 1.1 3.6 4.0 3.8 3.3 3.1 4.1 4.9 4.2 4.7 4.2 4.3 4.9 2.4 3.2 4.1 2.6 11.7 1.3 1.1 2.5 2.2 0.1 3.8 2.4 3.0 2.8 4.3 7.3 0.0 1.5 79.4 12.0 0.0 3.0 0.3 4.7 3.1 2.9 7.2 7.0 0.3 7.6 1.4 4.0 2.0 5.1 2.5 2.9 4.2 30.2 7.2 1.7 0.5 6.1 2.0 6.7 8.4 0.7 4.7 9.5 5.4 2.8 5.6 1.1 15.5 0.5 1.2 5.6 2.5 4.5 5.2 1.5 17.7 5.6 5.2 0.9 0.0 3.5 1.9 0.8 0.6 2.0 2.4 0.3 11.8 4.5 7.4 1.2 ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 ABO "A3GALNT, A3GALT1" ENSG00000175164 "ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase" 9 133233278-133276024 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 13.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 54.6;Intestinal goblet cells: 55.3;Proximal enterocytes: 194.0;Undifferentiated cells: 60.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.0;naive B-cell: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 22.4;HaCaT: 15.4;K-562: 16.5;OE19: 20.6;RT4: 7.2" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.78e-3)" "unprognostic (2.56e-3)" "unprognostic (1.38e-1)" "unprognostic (1.87e-3)" "unprognostic (1.39e-1)" "unprognostic (3.10e-2)" "unprognostic (1.84e-3)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" "unprognostic (8.51e-2)" "unprognostic (9.30e-3)" "unprognostic (7.23e-2)" "unprognostic (2.67e-2)" "unprognostic (4.57e-3)" "unprognostic (1.50e-1)" "unprognostic (2.34e-1)" "unprognostic (9.04e-2)" 1.1 3.3 3.0 5.1 4.3 1.7 1.3 3.1 3.6 0.5 5.4 7.1 3.2 1.3 1.4 6.1 9.5 3.3 0.3 4.4 3.3 3.8 0.5 3.4 0.4 1.8 2.3 10.3 3.3 3.6 0.5 0.4 1.7 1.3 0.9 1.5 1.3 1.9 1.8 1.1 13.3 0.8 2.5 0.5 6.1 2.7 3.9 0.1 5.3 0.5 0.5 1.4 2.4 3.9 4.8 0.0 0.2 0.2 0.5 0.0 0.5 0.0 0.6 0.3 0.0 0.0 22.4 0.2 1.0 0.0 0.0 15.4 0.0 0.0 0.0 0.2 0.0 2.5 1.1 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.3 0.1 16.5 2.2 0.4 0.0 1.8 0.3 1.5 20.6 0.0 0.1 0.0 0.0 0.0 7.2 0.1 0.8 0.9 0.6 0.0 0.0 0.7 0.1 0.1 0.3 0.2 0.2 0.0 0.3 0.6 0.5 0.1 0.0 0.2 0.8 0.1 2.0 0.1 0.5 0.0 0.1 0.5 0.0 0.0 2.1 0.4 0.3 0.5 0.0 0.0 0.2 0.2 1.5 3.0 4.3 3.1 3.6 4.4 3.3 1.8 2.3 1.7 2.5 3.9 3.9 10.0 32.1 32.2 1.0 1.5 0.0 3.8 0.0 11.4 0.0 4.5 2.5 3.2 11.5 14.9 47.8 0.0 1.3 0.3 38.1 0.0 5.0 5.7 14.8 1.1 9.2 25.5 11.8 3.8 0.4 0.3 5.2 22.4 10.6 0.0 54.6 3.3 0.2 0.3 0.0 0.4 55.3 0.0 1.0 0.0 10.0 15.2 9.2 0.0 4.7 0.9 0.0 0.0 0.0 0.1 6.1 42.0 6.8 0.1 7.0 194.0 24.1 30.6 0.3 6.6 0.2 5.9 0.9 2.5 25.9 0.0 0.7 3.1 42.0 60.5 16.5 AC008687.1 ENSG00000267335 "Novel protein" 19 49022953-49036895 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "pituitary gland: 17.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.6;HMC-1: 4.4;U-138 MG: 1.6;U-251 MG: 6.0" HPA038925 Uncertain Approved Cytosol "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" Cytosol "HPA038925: AB_2676272" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.7 0.0 17.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.6 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.6 0.0 0.2 0.0 0.0 1.6 1.3 0.3 6.0 0.3 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 AC233755.1 ENSG00000275063 "Immunoglobulin heavy variable 4-38-2-like" P0DP08 Unmapped 41444-41876 "Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 624.1;lymphoid tissue: 768.6;urinary bladder: 434.2" "Cell type enriched" "Detected in some" 196 "Plasma cells: 4861.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in some" 368 "memory B-cell: 403.0;naive B-cell: 259.1" "Lineage enriched" "Detected in single" 447 "B-cells: 403.0" "Cell line enriched" "Detected in some" 7 "REH: 141.7" "Secreted to blood" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" 33.8 2.1 0.3 332.3 0.0 86.5 76.2 0.0 1.1 193.2 0.7 624.1 464.1 5.9 0.0 101.8 3.7 40.5 1.7 0.0 0.1 2.4 21.2 37.2 126.7 0.2 0.0 11.9 1.4 0.0 1.0 0.0 4.4 222.0 0.0 188.6 21.5 0.2 0.7 136.0 30.3 0.1 211.6 242.0 7.8 0.0 34.3 3.3 0.0 768.6 434.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.1 1.0 0.0 0.0 0.0 19.1 0.4 0.4 0.0 0.0 141.7 1.6 3.2 0.0 0.0 0.2 9.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.0 3.6 0.0 0.7 0.0 0.3 0.2 0.1 0.1 0.0 0.5 403.0 0.2 0.2 0.2 259.1 0.2 0.1 0.6 0.1 0.1 0.9 0.2 34.3 0.3 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4861.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 ACAN "AGC1, CSPG1, CSPGCP, MSK16" ENSG00000157766 Aggrecan P16112 15 88803436-88875353 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.5;seminal vesicle: 3.1" "Group enriched" "Detected in some" 15 "Extravillous trophoblasts: 127.1;Granulosa cells: 132.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "WM-115: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016377, HPA038241, HPA038242" Enhanced "Secreted to extracellular matrix" NA NA 17000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB016377: AB_626650, HPA038241: AB_2675909, HPA038242: AB_2675910" "unprognostic (2.69e-3)" "unprognostic (4.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.43e-2)" "unprognostic (2.13e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-1)" "unprognostic (7.12e-2)" "unprognostic (8.57e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (7.79e-2)" "unprognostic (1.53e-1)" "unprognostic (7.71e-2)" "unprognostic (7.27e-2)" 1.2 0.2 0.6 0.9 1.0 0.1 0.1 2.2 1.6 0.9 0.1 0.3 0.1 0.4 0.2 0.1 0.2 0.7 0.5 0.7 6.5 0.7 0.1 0.7 0.1 2.1 1.6 0.4 0.2 0.1 0.4 0.2 1.5 0.5 0.3 0.1 0.1 3.1 0.2 0.2 0.1 0.5 1.3 0.2 0.2 1.4 1.5 0.0 0.3 0.0 0.0 0.8 0.7 1.4 0.0 0.0 0.0 0.0 0.8 0.0 4.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.2 1.6 0.7 6.5 2.1 1.6 1.5 1.3 1.5 1.4 0.1 0.0 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.0 1.2 0.0 127.1 0.7 0.0 0.4 1.3 132.4 0.0 0.0 2.5 0.0 4.5 0.0 0.0 0.0 0.5 2.1 0.0 0.2 1.8 1.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 8.4 2.3 6.3 0.0 0.4 3.6 0.1 1.8 0.0 0.4 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACE2 ENSG00000130234 "Angiotensin I converting enzyme 2" Q9BYF1 X 15494566-15607236 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 65.5;intestine: 242.2;kidney: 87.6" "Cell type enriched" "Detected in many" 5 "Proximal enterocytes: 294.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 13.9;renal cancer: 26.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.2;NTERA-2: 1.2;SuSa: 1.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174, CAB026213, CAB080024, CAB080025, CAB080027, CAB080028" Enhanced "Secreted to blood" NA NA 400000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 45: Enterocytes - Digestion" "CAB026174: , CAB026213: , CAB080024: AB_10864415, CAB080025: AB_2809589, CAB080027: AB_2665870, CAB080028: AB_2665871, HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favorable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favorable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" 8.9 0.5 0.1 1.4 0.1 0.6 4.3 0.4 0.3 0.6 1.9 9.9 183.3 0.5 0.5 1.8 1.5 65.5 42.7 0.2 0.2 87.6 5.7 0.8 0.4 0.2 0.2 1.8 2.5 1.5 0.1 1.2 0.2 0.4 5.9 0.3 1.4 4.1 0.7 0.3 242.2 0.5 0.1 0.1 2.6 49.7 0.2 0.5 4.5 0.5 0.2 0.8 1.2 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.8 0.1 0.0 0.2 0.2 0.2 0.3 0.4 0.3 0.0 0.3 0.7 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.5 1.2 1.2 0.0 0.0 0.3 0.2 0.5 0.2 0.4 0.2 0.9 0.0 0.4 0.0 1.9 0.4 0.4 0.1 0.0 0.0 0.3 0.4 0.1 0.5 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.5 1.3 1.4 0.1 0.5 5.0 0.0 0.0 1.6 0.0 11.2 55.8 2.6 0.0 0.0 4.2 0.1 22.9 3.9 1.2 0.5 1.1 0.3 1.0 7.2 0.0 0.8 0.8 0.3 4.6 0.0 0.6 0.0 3.9 0.0 0.9 0.8 0.0 0.8 8.2 0.0 0.0 0.0 1.4 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 5.1 6.0 0.0 1.0 294.8 48.8 2.0 0.0 19.7 0.0 8.9 1.1 1.0 0.0 0.1 12.7 0.3 0.1 10.6 2.2 ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368298 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 76 "prostate: 3643.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Hofbauer cells: 4.7;Syncytiotrophoblasts: 8.9" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 139.7" "Lineage enhanced" "Detected in many" "granulocytes: 139.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.7;OE19: 22.3;RPMI-8226: 58.0;U-698: 17.2;U-87 MG: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" NA NA 460000 480000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 3.1 5.4 0.9 7.3 1.3 17.5 3.4 0.9 0.9 6.3 1.2 3.6 3.1 1.4 17.2 47.7 2.2 1.5 0.6 1.2 1.5 28.9 1.4 4.5 1.9 1.5 1.3 1.1 2.7 3.9 0.5 10.8 1.5 3643.7 6.5 0.4 10.6 0.8 0.2 27.0 3.4 1.8 1.0 1.8 3.2 2.4 1.0 1.0 2.4 0.2 6.5 1.8 12.1 1.7 0.5 0.1 0.0 0.0 0.2 0.9 11.7 0.3 17.7 0.1 0.0 0.4 0.4 10.6 0.8 0.0 0.1 4.8 0.0 0.1 0.0 0.1 0.5 2.0 0.4 0.2 0.2 7.3 0.1 1.1 1.6 0.1 0.0 0.2 0.0 0.0 0.1 2.7 0.2 0.1 0.0 13.5 0.7 22.3 2.1 0.1 0.0 58.0 5.0 6.5 0.0 4.1 0.1 2.0 0.6 1.7 0.3 6.5 0.0 0.1 0.1 2.5 0.1 0.8 0.4 17.2 14.9 12.7 0.2 0.1 30.2 139.7 0.2 26.9 0.2 0.7 0.0 0.0 35.3 0.0 0.0 0.0 26.4 2.6 25.8 2.4 0.0 10.1 0.9 1.3 0.9 0.9 1.2 1.5 1.5 1.3 1.5 1.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.6;lymphoid tissue: 2.6;skin 1: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 33.3;U-87 MG: 45.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" 0.0 0.0 1.7 0.0 3.3 0.0 0.2 6.6 2.7 0.7 0.8 0.0 0.0 0.0 0.4 0.7 0.0 0.2 0.0 2.0 2.2 0.0 0.0 0.0 0.0 3.9 3.7 0.0 0.0 0.3 0.0 0.0 3.8 0.3 0.0 0.0 0.5 0.0 0.0 6.0 0.0 0.0 2.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 2.6 0.1 0.6 4.1 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.6 0.8 0.4 5.2 0.0 0.0 0.0 33.3 0.3 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.5 0.3 0.0 0.1 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.1 1.1 0.0 0.0 0.0 0.0 0.0 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.3 6.6 2.7 2.0 2.2 3.9 3.7 3.8 2.0 3.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 ACR ENSG00000100312 Acrosin P10323 22 50738196-50745339 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 86.7" "Group enriched" "Detected in some" 33 "Early spermatids: 492.2;Late spermatids: 134.8;Spermatocytes: 216.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA048687 Enhanced "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA048687: AB_2680494" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.27e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (3.30e-3)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" 2.6 0.2 0.4 0.0 0.5 0.0 2.0 0.4 0.5 0.8 2.6 0.5 0.1 1.1 0.7 0.4 1.1 0.2 1.0 0.4 0.3 0.9 0.8 2.0 0.0 0.3 0.3 0.3 0.2 0.0 0.5 0.1 0.5 0.6 0.0 0.1 0.6 0.2 0.8 0.8 0.5 0.2 0.4 3.0 0.3 86.7 0.4 0.0 0.6 0.0 0.0 0.6 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.5 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.4 8.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 492.2 0.4 0.1 4.7 3.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.5 0.1 0.1 0.0 0.2 0.8 0.0 0.0 0.0 134.8 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.8 2.6 0.0 0.0 1.2 0.4 0.0 0.0 6.6 0.3 0.1 216.9 2.5 0.3 0.0 0.0 0.0 0.1 1.5 0.2 ACRBP "CT23, OY-TES-1, SP32" ENSG00000111644 "Acrosin binding protein" Q8NEB7 12 6638075-6647433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "testis: 283.5" "Cell type enhanced" "Detected in many" "Early spermatids: 1097.8;Late spermatids: 723.5;Macrophages: 220.0;Spermatocytes: 387.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "classical monocyte: 12.5;intermediate monocyte: 15.8;myeloid DC: 17.7;non-classical monocyte: 31.0" "Group enriched" "Detected in many" 9 "dendritic cells: 17.7;monocytes: 31.0" "Cell line enhanced" "Detected in some" "HEL: 5.3;HMC-1: 6.7;U-266/70: 15.0;U-266/84: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039081, HPA039082" Enhanced Approved Nucleoplasm,Vesicles "Secreted in male reproductive system" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA039081: AB_10670920, HPA039082: AB_10671036" "unprognostic (7.76e-3)" "unprognostic (2.27e-1)" "unprognostic (3.41e-3)" "unprognostic (2.31e-2)" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (2.42e-1)" "unprognostic (3.40e-3)" "unprognostic (2.85e-1)" "unprognostic (5.47e-3)" "unprognostic (1.17e-2)" "unprognostic (1.43e-1)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-4)" 2.2 0.9 0.9 3.8 1.3 10.7 1.1 1.9 1.4 1.9 1.1 2.9 8.4 1.4 14.2 0.9 2.1 4.1 0.6 0.9 1.0 1.8 2.2 2.8 5.5 1.3 1.2 0.7 2.9 0.3 0.9 2.3 1.3 2.0 2.1 1.8 1.3 1.1 0.4 1.7 8.1 2.1 1.1 9.2 1.9 283.5 1.2 3.0 13.8 0.4 3.6 2.4 0.9 1.5 0.2 0.1 0.8 2.5 0.8 1.2 1.3 0.0 0.0 0.1 0.1 0.0 1.8 0.3 0.8 0.2 0.1 0.0 0.4 0.0 0.2 0.8 0.0 5.3 0.6 0.0 1.8 0.1 6.7 0.1 3.3 0.9 0.1 0.6 0.6 1.7 3.5 0.0 0.1 0.3 0.2 1.9 1.5 4.3 0.0 0.3 0.1 0.3 0.5 0.1 1.0 0.3 0.0 0.7 1.1 1.2 0.0 1.9 0.7 0.1 0.8 0.5 0.0 15.0 10.5 0.5 0.5 2.0 0.0 1.5 12.5 1.2 0.2 15.8 0.0 1.3 0.0 0.0 17.7 1.9 0.2 0.1 2.6 0.7 31.0 4.5 0.0 10.6 0.9 1.3 1.9 1.4 0.9 1.0 1.3 1.2 1.3 1.1 1.2 1.5 0.3 0.0 1.3 0.7 1.5 0.1 0.1 0.0 1.2 1.7 0.5 0.5 1.0 0.0 0.1 0.0 0.0 0.1 1.9 0.9 0.0 0.2 1097.8 0.7 0.5 1.5 0.0 5.7 0.2 0.5 0.3 0.5 0.0 0.8 6.3 0.4 1.8 0.3 9.8 0.0 0.3 0.8 0.0 20.5 3.4 723.5 8.1 220.0 0.0 1.0 7.6 1.1 10.3 0.0 0.4 0.1 1.6 4.5 0.5 0.0 7.6 1.1 0.2 1.3 6.6 0.3 0.2 387.5 7.5 0.3 0.0 0.1 1.0 0.4 1.1 0.1 ACRV1 "D11S4365, SP-10, SPACA2" ENSG00000134940 "Acrosomal vesicle protein 1" P26436 11 125671522-125680874 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 116.7" "Group enriched" "Detected in some" 48 "Early spermatids: 904.8;Late spermatids: 278.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 5.0;HEL: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038718, HPA038719" Enhanced "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "HPA038718: AB_2676171, HPA038719: AB_10670787" "unprognostic (3.58e-2)" "unprognostic (8.68e-3)" "unprognostic (1.46e-1)" "unprognostic (6.18e-2)" "unprognostic (4.58e-2)" "unprognostic (7.91e-3)" "unprognostic (6.73e-4)" "unprognostic (1.76e-1)" "unprognostic (2.12e-3)" "unprognostic (8.39e-2)" "unprognostic (7.09e-2)" "unprognostic (2.90e-3)" "unprognostic (1.80e-8)" "unprognostic (5.26e-3)" "unprognostic (2.52e-1)" "unprognostic (1.95e-1)" "unprognostic (3.75e-1)" 0.0 0.0 1.8 0.1 1.9 0.2 0.1 1.3 2.0 0.0 1.2 0.1 0.1 0.1 3.5 0.0 0.1 0.0 0.0 1.7 1.6 0.0 0.0 0.0 0.4 1.5 1.5 0.0 0.0 0.0 0.2 0.1 1.6 0.2 0.0 0.2 0.0 0.7 0.0 0.1 0.1 0.2 1.6 0.0 0.0 116.7 1.9 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.3 1.2 5.0 3.2 0.0 0.0 1.0 1.5 0.0 0.1 0.0 1.8 1.7 2.7 0.6 0.0 0.7 0.4 0.0 0.0 0.3 1.9 0.9 5.0 0.6 0.9 0.1 2.5 1.1 0.0 0.0 0.0 0.2 0.2 0.0 0.8 1.4 2.0 0.4 0.7 2.7 3.4 1.1 0.5 1.0 2.3 1.2 0.5 0.0 0.5 0.6 0.8 0.6 0.1 0.1 0.9 0.9 0.6 0.5 1.7 1.1 0.2 0.3 0.9 1.2 1.3 0.2 1.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 1.9 1.3 2.0 1.7 1.6 1.5 1.5 1.6 1.6 1.9 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 904.8 0.8 0.1 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 278.8 6.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17258235 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 106.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Glandular and luminal cells: 22.0;Hofbauer cells: 57.6;Macrophages: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.7;EFO-21: 21.4;HUVEC TERT2: 24.0;Karpas-707: 44.9;MOLT-4: 38.9;U-266/70: 23.8;U-937: 39.6" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favorable (9.26e-4)" "prognostic favorable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" 14.0 11.3 8.3 39.4 9.9 22.8 17.6 10.6 7.9 22.0 20.5 28.3 18.1 19.9 2.7 12.0 51.5 32.1 39.6 7.8 10.9 14.5 21.1 54.9 47.3 16.3 11.4 12.1 13.9 5.4 22.5 15.2 14.7 15.4 34.3 11.0 15.6 17.1 3.4 4.7 26.1 23.4 13.7 106.3 19.6 18.4 12.9 53.7 16.9 4.3 60.7 34.7 6.5 21.1 0.0 0.0 6.4 0.0 0.2 0.8 0.3 2.3 0.1 0.0 0.0 0.0 23.7 6.0 21.4 7.2 0.0 0.5 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.0 0.3 0.3 11.3 0.1 0.0 0.1 0.1 24.0 9.0 0.1 44.9 0.9 0.0 38.9 1.1 17.8 0.0 0.1 1.2 0.0 6.5 0.0 9.3 10.9 0.1 0.1 0.0 0.0 19.1 0.2 9.7 3.0 0.1 0.2 0.0 0.0 23.8 2.3 1.7 0.0 39.6 0.0 17.5 212.9 11.3 34.6 204.9 26.8 25.8 27.4 34.1 139.1 19.7 31.6 32.4 10.5 44.9 176.1 57.4 17.2 170.7 8.3 9.9 10.6 7.9 7.8 10.9 16.3 11.4 14.7 13.7 12.9 21.1 8.7 0.0 16.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.0 0.0 11.2 5.5 0.0 0.4 13.7 0.0 7.9 1.7 0.0 27.6 6.6 2.2 0.0 0.0 0.0 5.2 0.9 2.1 0.0 22.0 5.1 12.6 0.0 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 12.4 0.0 0.0 3.1 15.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 8.2 3.1 0.0 0.0 ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388455 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 166.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2;Extravillous trophoblasts: 400.8;Oligodendrocyte precursor cells: 99.0;Syncytiotrophoblasts: 129.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "MAIT T-cell: 6.1" "Lineage enriched" "Detected in single" 62 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 154.2;hTEC/SVTERT24-B: 94.3;U-2197: 93.2;U-251 MG: 86.2;U-87 MG: 70.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" 11.4 0.1 2.0 6.0 4.0 0.1 4.6 1.6 2.1 18.2 3.5 0.4 0.2 6.3 0.0 0.4 0.2 11.8 0.7 1.0 2.5 1.0 0.2 1.3 3.2 6.0 2.7 8.8 0.5 0.1 1.1 166.5 3.1 0.3 0.6 0.3 1.1 0.0 0.1 0.4 0.5 4.3 1.8 1.6 0.5 0.9 10.4 1.8 0.3 0.0 3.5 11.6 0.5 3.0 16.8 2.5 6.5 0.1 18.7 38.3 0.0 42.7 3.5 14.2 35.5 0.0 0.0 0.0 0.0 154.2 30.0 0.0 0.2 1.4 15.5 1.9 0.6 0.2 25.1 0.0 2.9 0.0 33.2 47.0 0.0 94.3 2.9 27.1 0.0 0.0 0.0 0.2 11.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 4.8 4.4 0.4 44.1 0.5 28.4 5.0 0.0 0.7 2.5 0.1 0.1 0.0 50.9 16.9 93.2 86.2 0.0 0.5 0.0 70.7 0.1 32.3 0.0 0.0 0.0 0.3 0.0 6.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 2.0 4.0 1.6 2.1 1.0 2.5 6.0 2.7 3.1 1.8 10.4 3.0 0.5 0.0 1.9 22.5 0.3 1.5 0.4 3.0 0.0 2.1 1.7 3.6 2.3 0.0 0.5 0.0 102.2 14.0 0.5 0.7 0.0 8.0 10.9 10.7 16.6 1.6 0.0 0.0 7.4 1.1 400.8 34.5 0.5 1.8 49.5 7.8 2.5 0.2 15.5 6.7 19.0 1.0 4.1 0.6 3.1 1.7 16.8 0.8 1.8 14.0 9.0 3.3 1.0 99.0 52.2 2.2 0.1 0.7 0.3 1.0 0.7 0.4 6.5 30.5 0.0 5.1 13.4 6.0 5.0 0.0 0.6 129.2 4.7 28.1 0.9 0.5 ADAM23 MDC3 ENSG00000114948 "ADAM metallopeptidase domain 23" O75077 2 206443532-206621127 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.7;parathyroid gland: 82.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 410.0;Inhibitory neurons: 236.6;Oligodendrocyte precursor cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "memory CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 16 "T-cells: 2.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 54.4;RH-30: 63.8;RPMI-8226: 172.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033276 Approved "Secreted in brain" NA NA 890000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB033276: AB_2305247" "unprognostic (7.33e-2)" "unprognostic (7.80e-2)" "unprognostic (4.60e-1)" "unprognostic (5.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.59e-2)" "unprognostic (4.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (6.84e-2)" "unprognostic (1.09e-2)" "unprognostic (2.64e-2)" "unprognostic (9.75e-6)" "unprognostic (3.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-3)" "unprognostic (1.03e-3)" 1.7 7.5 14.3 2.4 20.6 2.0 1.1 3.5 45.7 3.2 0.0 3.0 1.5 2.2 3.8 4.0 0.8 4.2 30.7 20.6 9.6 0.9 0.3 1.5 2.1 13.9 10.2 2.0 1.2 82.9 6.4 0.2 12.9 1.7 2.2 17.4 1.5 2.4 11.1 1.1 3.2 4.5 1.6 0.8 1.6 8.0 17.4 4.9 1.0 8.7 2.7 3.0 4.1 24.0 0.1 0.9 22.3 0.0 11.9 17.2 0.9 2.4 2.9 3.2 0.6 26.8 0.5 3.3 0.0 3.8 39.5 33.9 14.5 0.7 0.3 13.2 12.4 0.0 2.1 0.3 11.4 0.3 1.4 6.5 0.1 0.1 0.0 54.4 39.4 1.2 0.0 0.1 8.2 0.4 0.3 0.0 43.9 0.4 4.6 0.1 63.8 172.6 0.0 16.6 17.4 7.0 0.0 0.0 12.9 10.9 0.1 0.0 34.3 11.1 10.2 6.0 5.3 45.2 0.1 0.0 21.1 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.3 20.6 3.5 45.7 20.6 9.6 13.9 10.2 12.9 1.6 17.4 24.0 1.6 0.0 0.0 41.8 0.4 0.4 0.9 0.1 0.6 39.3 0.0 0.1 62.8 0.0 0.0 1.8 2.1 0.0 0.1 0.0 0.0 0.0 17.6 0.3 7.7 2.7 1.8 0.0 410.0 0.0 0.0 4.3 0.0 0.2 0.0 15.0 0.0 0.1 0.0 3.3 236.6 0.0 0.0 0.0 0.3 57.7 0.6 0.1 3.6 10.3 0.0 4.1 0.0 127.2 22.3 0.1 1.1 3.0 0.0 0.5 0.0 0.0 0.7 6.8 0.0 14.2 2.2 5.1 4.7 1.5 0.4 0.1 2.0 45.2 0.0 0.1 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 179.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" NA NA 740000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" 34.2 28.0 7.1 28.8 8.2 2.1 21.5 8.5 8.3 34.8 11.4 32.9 24.5 29.7 15.2 29.7 19.3 47.1 32.1 6.0 8.4 34.9 13.5 51.4 9.7 10.2 7.5 16.8 12.7 52.5 7.8 47.4 9.0 34.9 41.7 18.5 54.9 34.8 24.1 16.1 23.0 51.6 9.4 24.0 44.2 11.1 10.6 5.9 39.9 25.0 13.2 56.1 24.3 11.5 188.3 163.6 63.5 32.6 117.2 374.0 67.0 259.6 382.4 191.7 177.9 82.7 147.1 10.1 86.1 247.2 156.7 79.5 30.8 249.7 373.2 6.9 21.5 12.1 102.8 73.0 226.4 8.9 19.1 287.5 139.2 193.3 212.7 341.0 268.9 15.2 21.5 53.2 406.2 25.0 7.2 4.4 8.3 175.2 46.7 3.8 106.3 27.6 299.3 62.4 6.4 11.5 78.4 90.9 57.8 72.9 67.3 12.0 374.2 109.9 97.9 213.9 124.1 12.9 29.5 7.7 175.8 12.0 72.1 0.3 4.0 0.5 0.1 1.3 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 0.5 0.8 0.6 0.3 0.1 0.9 7.1 8.2 8.5 8.3 6.0 8.4 10.2 7.5 9.0 9.4 10.6 11.5 14.4 48.1 37.0 16.0 3.8 35.9 66.6 78.3 26.7 19.3 23.4 9.8 49.7 24.3 82.1 35.0 20.9 24.1 8.9 44.4 3.9 90.2 14.4 42.1 35.3 20.5 10.7 2.5 47.5 115.4 85.1 42.0 80.5 82.1 5.1 26.4 25.0 7.5 125.9 5.0 38.0 32.2 44.7 60.2 44.8 7.8 28.6 54.7 21.4 33.7 21.8 17.5 1.0 30.7 26.7 179.4 30.6 24.8 5.2 108.7 24.9 41.1 51.9 25.1 13.1 31.3 31.9 4.3 2.5 20.2 21.5 34.3 5.6 11.2 32.7 103.8 ADAMDEC1 M12.219 ENSG00000134028 "ADAM like decysin 1" O15204 8 24384285-24406013 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 424.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 14.8;Kupffer cells: 12.9;Macrophages: 25.5;monocytes: 5.2" "Cancer enhanced" "Detected in all" "testis cancer: 16.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 8 "U-266/70: 10.7;U-266/84: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 28000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.17e-2)" "unprognostic (1.80e-2)" "unprognostic (4.15e-3)" "unprognostic (3.60e-1)" "unprognostic (6.21e-2)" "unprognostic (3.84e-3)" "unprognostic (2.12e-1)" "unprognostic (2.90e-1)" "unprognostic (1.61e-1)" "unprognostic (5.99e-3)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (1.74e-2)" "unprognostic (2.06e-1)" "unprognostic (1.35e-2)" "unprognostic (3.66e-2)" "unprognostic (8.23e-2)" 0.6 0.5 0.0 52.1 0.0 0.3 0.6 0.0 0.8 0.4 0.0 215.4 189.4 0.9 0.2 0.9 0.1 3.2 0.4 0.1 0.0 0.2 0.1 1.6 73.3 0.3 0.0 0.1 0.2 0.0 0.0 7.8 0.3 0.8 311.5 0.0 0.7 0.4 0.0 0.4 424.9 11.6 0.0 5.8 5.9 0.3 0.4 5.7 0.3 0.0 27.2 20.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 10.7 2.7 0.0 0.0 0.0 0.0 0.0 0.7 1.9 0.0 0.8 0.0 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.0 2.2 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.1 0.0 0.0 12.9 2.0 0.0 0.0 25.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADAMTS10 ADAM-TS10 ENSG00000142303 "ADAM metallopeptidase with thrombospondin type 1 motif 10" Q9H324 19 8580240-8610735 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.3;Excitatory neurons: 21.4;Inhibitory neurons: 19.9;Microglial cells: 30.9;Skeletal myocytes: 15.9;Smooth muscle cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 7.2;hTERT-RPE1: 7.5;NB-4: 37.0;REH: 9.8" "Region enriched" "Detected in many" 5 "cerebellum: 8.8" "Low region specificity" "Detected in all" HPA040223 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA040223: AB_10795376" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (1.14e-1)" "unprognostic (8.16e-2)" "unprognostic (1.91e-4)" "unprognostic (4.98e-3)" "unprognostic (4.06e-2)" "unprognostic (2.24e-2)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (6.86e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-1)" "unprognostic (4.12e-2)" 15.9 8.2 7.1 2.3 7.3 1.8 9.5 5.0 11.9 13.0 5.8 7.3 0.8 12.7 0.7 4.1 10.2 1.9 8.5 7.6 8.7 6.9 6.3 8.2 3.2 7.1 6.8 8.3 7.8 0.8 4.1 1.7 6.7 8.4 0.5 0.4 4.1 1.5 2.8 8.8 6.3 1.5 6.0 5.4 3.8 2.4 8.1 1.4 6.2 0.8 1.3 5.7 8.7 6.5 0.0 4.6 2.5 0.0 0.4 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.2 1.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.0 7.2 0.0 0.3 0.0 0.1 1.8 0.0 0.0 0.0 7.5 0.1 0.3 0.1 0.0 0.0 0.0 0.3 37.0 1.5 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.2 0.1 0.4 2.0 3.1 4.4 2.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 7.3 5.0 11.9 7.6 8.7 7.1 6.8 6.7 6.0 8.1 6.5 5.6 0.0 0.0 18.3 0.3 1.7 0.6 0.1 0.0 1.5 1.2 1.5 1.3 5.7 0.1 0.0 0.0 0.1 6.9 0.0 0.0 8.8 5.1 0.4 7.4 5.8 0.0 1.3 21.4 0.5 0.0 6.4 1.1 0.4 0.0 1.8 6.8 2.0 0.9 0.0 19.9 0.3 0.0 2.7 6.0 2.4 7.5 3.3 0.0 30.9 0.6 0.8 11.3 9.5 1.2 0.9 0.0 6.0 1.3 0.2 0.0 0.1 0.0 0.2 6.6 15.9 15.0 0.1 0.4 0.1 0.9 0.4 3.2 0.6 0.1 0.3 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Early spermatids: 19.3;Excitatory neurons: 12.4;Inhibitory neurons: 12.4;Late spermatids: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 120000000 "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 2.5 2.8 6.9 0.5 7.3 0.6 2.8 7.6 10.0 5.0 5.3 4.3 3.2 4.2 2.9 2.4 5.7 1.2 6.0 7.1 6.2 9.6 63.8 2.8 0.9 7.0 6.7 6.7 6.2 1.5 12.5 0.8 7.1 6.4 0.9 1.1 2.5 1.4 4.3 2.6 4.4 0.6 6.3 2.6 9.8 13.5 7.2 0.8 6.1 1.4 0.5 4.4 3.1 7.1 0.0 0.8 1.9 2.6 1.5 1.3 0.8 0.7 0.5 0.2 0.3 0.3 2.1 0.2 0.9 0.4 0.6 0.3 0.1 0.4 0.1 1.2 1.7 0.2 0.9 0.4 1.1 0.0 0.7 3.6 0.9 0.2 0.7 1.2 0.1 1.3 0.0 0.8 0.3 3.3 0.0 0.9 2.0 1.1 1.1 0.2 0.2 0.9 0.8 0.8 1.3 4.0 1.4 0.6 1.2 3.9 3.7 0.4 0.5 1.5 0.8 0.9 0.0 1.7 0.3 0.3 1.1 0.2 1.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.3 7.6 10.0 7.1 6.2 7.0 6.7 7.1 6.3 7.2 7.1 0.9 0.0 2.0 16.0 1.2 0.3 0.3 0.9 0.0 1.7 1.4 1.9 4.2 4.3 2.4 0.0 0.0 0.2 0.2 1.0 1.9 0.6 19.3 3.6 1.6 0.9 1.2 0.0 12.4 0.4 0.3 1.5 4.6 3.3 0.0 3.0 5.0 1.6 0.2 3.3 12.4 1.3 0.0 0.6 0.0 13.6 0.9 0.3 0.0 7.5 0.0 1.7 0.0 2.0 5.5 0.3 3.0 1.5 0.4 0.4 1.5 0.9 0.7 1.8 0.0 0.4 0.7 6.0 3.9 0.3 0.4 0.1 0.5 1.7 0.9 0.3 ADAMTS14 ENSG00000138316 "ADAM metallopeptidase with thrombospondin type 1 motif 14" Q8WXS8 10 70672506-70762441 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.9;gallbladder: 6.7;placenta: 7.6" "Group enriched" "Detected in some" 5 "Oligodendrocytes: 44.8;Paneth cells: 14.6;Theca cells: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.1;K-562: 10.4;RH-30: 5.4;U-138 MG: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (5.98e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-3)" "unprognostic (2.40e-1)" "unprognostic (5.33e-3)" "unprognostic (2.35e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.98e-2)" "unprognostic (6.81e-2)" "unprognostic (3.84e-13)" "unprognostic (3.90e-2)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" "unprognostic (2.16e-2)" 0.8 0.2 2.6 3.2 5.9 0.6 0.3 2.0 5.4 1.0 0.4 2.7 2.3 0.7 0.4 1.0 0.5 6.7 0.7 2.9 3.7 0.5 0.3 1.7 1.1 3.2 4.3 0.2 0.2 0.0 0.1 7.6 3.2 0.6 1.8 0.0 0.8 0.1 0.1 1.3 3.2 2.2 1.4 0.4 1.4 0.5 10.9 0.4 0.2 0.3 0.7 2.5 0.4 9.9 0.0 0.0 0.1 0.3 0.2 4.0 0.0 1.0 3.2 0.3 1.7 0.0 9.1 0.0 0.7 1.7 0.4 0.7 0.0 0.0 0.1 3.6 0.0 0.3 0.0 0.2 0.0 0.0 2.4 0.3 0.1 0.8 0.2 1.0 0.0 0.0 10.4 0.0 1.3 0.0 0.0 0.9 0.3 0.1 0.0 0.0 5.4 0.2 0.0 0.0 3.4 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 8.9 0.1 0.7 0.5 0.8 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.9 2.0 5.4 2.9 3.7 3.2 4.3 3.2 1.4 10.9 9.9 0.1 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.1 0.5 0.1 0.3 0.0 2.1 0.3 0.0 0.1 2.1 0.0 0.2 4.5 0.1 0.0 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.0 44.8 0.1 14.6 0.0 0.1 0.0 0.7 0.0 1.4 0.0 0.0 1.8 1.1 0.0 0.0 0.2 0.1 0.4 0.0 17.9 0.5 0.1 ADAMTS15 ENSG00000166106 "ADAM metallopeptidase with thrombospondin type 1 motif 15" Q8TE58 11 130448974-130476641 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 26.4" "Cell type enhanced" "Detected in some" "Adipocytes: 8.6;Cardiomyocytes: 11.0;Endometrial stromal cells: 15.6;Fibroblasts: 9.6;Gastric mucus-secreting cells: 8.2;Glandular and luminal cells: 7.5;Granulosa cells: 6.8;Skeletal myocytes: 6.9" "Cancer enhanced" "Detected in many" "breast cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 72.0;ASC TERT1: 43.0;EFO-21: 36.6;hTERT-RPE1: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA042867 Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA042867: AB_10794535" "unprognostic (7.64e-2)" "unprognostic (1.49e-3)" "unprognostic (7.15e-2)" "unprognostic (1.34e-3)" "unprognostic (1.07e-3)" "unprognostic (7.07e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.72e-4)" "unprognostic (6.18e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (7.40e-2)" "unprognostic (1.29e-2)" "unprognostic (5.95e-3)" "unprognostic (6.68e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.63e-5)" 26.4 1.2 0.4 1.7 0.5 0.0 15.3 0.4 0.8 3.4 1.7 3.2 0.5 4.3 1.3 3.7 9.8 2.3 14.5 0.4 0.9 11.0 0.4 7.2 1.1 4.4 0.6 2.7 1.4 0.4 1.3 16.9 1.5 1.9 1.9 0.2 1.3 1.1 1.8 5.0 3.6 4.6 1.0 2.3 5.5 0.9 1.2 1.1 7.0 1.0 0.3 8.8 2.6 1.0 0.0 2.6 1.6 0.8 72.0 43.0 0.0 2.7 5.2 1.0 0.2 0.5 1.2 0.0 36.6 0.2 2.6 7.0 0.6 0.7 0.2 0.0 1.7 0.0 3.3 0.0 0.7 0.0 0.0 14.1 0.0 0.6 0.1 19.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 8.1 1.3 0.0 5.7 0.0 4.1 0.0 0.1 0.1 0.6 0.0 12.1 0.0 0.0 5.2 3.9 0.0 0.0 0.6 8.5 7.0 3.5 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.8 0.4 0.9 4.4 0.6 1.5 1.0 1.2 1.0 8.6 0.0 0.0 0.3 0.2 0.5 0.1 3.5 0.0 1.3 5.6 2.7 11.0 0.0 0.5 1.8 0.0 0.6 0.0 1.0 0.0 0.0 0.0 4.4 15.6 1.7 0.0 0.0 0.4 0.8 0.6 9.6 8.2 7.5 0.0 6.8 0.4 0.1 0.9 0.0 1.6 0.5 2.0 0.0 0.3 0.0 5.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.9 0.7 0.0 0.0 0.1 1.0 0.5 0.0 0.0 6.9 3.6 0.2 0.3 0.0 0.3 0.8 0.1 0.0 1.8 0.1 ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 7.3;Excitatory neurons: 44.7;Fibroblasts: 13.7;Granulosa cells: 22.2;Theca cells: 15.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;SuSa: 3.5;U-2197: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067668 Approved "Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria" "Secreted to extracellular matrix" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" "Nucleoplasm, Midbody ring" "HPA067668: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" 5.4 0.2 1.4 0.4 1.9 0.5 0.7 17.0 2.6 1.4 0.0 0.7 0.6 1.3 1.6 1.5 0.7 6.4 0.2 3.4 0.0 3.5 0.4 0.7 0.2 0.2 0.2 10.4 4.5 0.1 0.0 0.2 0.7 0.1 0.3 1.2 0.2 0.5 0.2 0.4 0.5 1.1 0.0 0.2 0.2 0.4 0.0 0.2 0.3 0.2 0.1 1.0 0.6 1.8 1.7 1.7 1.7 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.5 0.0 1.4 0.1 2.1 0.0 3.0 0.1 0.0 0.0 0.4 0.1 0.9 0.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.1 0.5 0.0 0.3 0.6 0.4 0.7 0.0 0.4 0.2 1.1 0.0 1.6 0.4 2.2 0.1 0.0 0.1 0.5 0.1 0.1 0.1 0.1 3.5 0.1 0.1 0.1 2.1 3.0 5.8 1.4 0.9 0.3 0.1 3.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 1.9 17.0 2.6 3.4 0.0 0.2 0.2 0.7 0.0 0.0 1.8 0.7 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.6 2.0 0.7 0.4 0.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 5.0 0.1 0.0 0.0 44.7 0.0 0.0 13.7 0.5 0.5 0.0 22.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 6.9 1.6 0.1 0.0 0.0 0.0 0.0 0.1 15.9 0.0 0.0 ADAMTS17 "FLJ16363, FLJ32769" ENSG00000140470 "ADAM metallopeptidase with thrombospondin type 1 motif 17" Q8TE56 15 99971437-100342005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Deafness, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.7" "Group enriched" "Detected in many" 8 "Astrocytes: 116.9;Early spermatids: 108.4;Inhibitory neurons: 275.7;Late spermatids: 91.0;Oligodendrocyte precursor cells: 337.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEK 293: 6.4;JURKAT: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062487 Approved Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA062487: AB_2684780" "unprognostic (7.73e-2)" "unprognostic (2.38e-2)" "unprognostic (1.79e-2)" "unprognostic (9.03e-3)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (5.78e-2)" "unprognostic (1.18e-3)" "unprognostic (5.03e-3)" "unprognostic (4.70e-2)" "unprognostic (2.93e-1)" "unprognostic (1.27e-1)" "unprognostic (3.35e-2)" "unprognostic (8.48e-2)" "unprognostic (1.21e-1)" "unprognostic (7.43e-3)" "unprognostic (6.43e-2)" 0.8 1.2 1.6 0.5 1.1 0.6 0.6 0.3 2.7 1.4 6.0 0.9 0.6 1.2 0.6 2.1 1.8 0.3 1.3 1.3 0.6 1.1 7.5 1.5 0.5 1.2 0.7 1.7 5.0 0.2 1.2 0.5 0.8 1.0 0.4 0.7 2.6 0.5 5.6 2.2 1.2 0.5 0.7 0.9 1.0 2.7 1.0 10.7 0.7 0.1 0.5 1.6 1.4 1.1 0.0 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.7 2.0 0.5 0.2 0.9 1.0 0.0 0.3 2.3 0.0 0.2 1.7 0.2 0.2 2.2 2.7 0.4 0.0 0.2 0.3 0.0 0.6 0.6 0.0 0.2 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.3 2.7 1.3 0.6 1.2 0.7 0.8 0.7 1.0 1.1 0.7 0.0 0.0 116.9 0.3 1.0 0.9 0.1 3.4 0.8 1.5 1.3 4.3 1.5 0.9 0.0 0.0 0.1 2.6 0.4 1.9 0.1 108.4 1.2 2.8 0.9 0.0 0.0 8.2 0.9 0.0 1.6 5.1 1.8 0.0 0.1 0.4 4.4 8.2 21.9 275.7 0.7 0.0 0.6 0.3 91.0 2.1 0.4 0.0 22.5 0.0 1.3 1.0 337.3 9.5 0.3 0.2 0.0 0.8 1.6 0.5 0.1 0.0 0.7 0.0 3.2 0.9 1.7 1.9 2.1 0.6 0.1 3.7 2.5 0.4 0.9 ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;placenta: 20.6" "Cell type enhanced" "Detected in some" "Adipocytes: 36.8;Granulosa cells: 15.0;Muller glia cells: 13.7;Oligodendrocytes: 16.9;Rod photoreceptor cells: 7.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 11.6;HUVEC TERT2: 8.0;SuSa: 10.6;TIME: 2.5;U-87 MG: 4.8" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Yes NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" 3.1 0.1 1.3 0.3 3.0 0.0 2.9 11.0 2.5 1.2 0.5 0.0 0.1 0.8 0.0 0.1 0.2 0.6 0.0 1.8 2.7 0.2 0.0 0.1 0.1 4.3 2.4 0.1 0.3 0.0 0.8 20.6 3.7 0.4 0.0 2.0 1.3 0.1 0.6 0.1 0.0 0.6 1.7 0.0 0.0 0.2 2.4 0.9 0.0 0.0 0.0 0.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.6 0.0 0.5 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.0 11.0 2.5 1.8 2.7 4.3 2.4 3.7 1.7 2.4 5.9 36.8 0.0 0.0 4.6 0.1 0.1 0.1 0.0 0.0 1.8 1.5 4.3 0.6 0.0 0.0 1.8 2.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.3 0.0 15.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.1 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.0 0.0 ADAMTS19 ENSG00000145808 "ADAM metallopeptidase with thrombospondin type 1 motif 19" 5 129460281-129738683 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "brain: 3.3;cervix: 10.2;endometrium 1: 9.8;placenta: 3.7;smooth muscle: 5.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 82.6;Inhibitory neurons: 79.7;Oligodendrocytes: 31.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.7;testis cancer: 1.2" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "MCF7: 15.9;SH-SY5Y: 34.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 2.6" "Low region specificity" "Detected in many" "HPA056171, HPA058438" Uncertain Approved Vesicles,Midbody "Secreted to extracellular matrix" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Midbody" "HPA056171: AB_2683054, HPA058438: AB_2683718" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-2)" "unprognostic (4.17e-2)" "unprognostic (5.99e-3)" "unprognostic (5.17e-1)" "unprognostic (1.14e-1)" "unprognostic (5.88e-2)" "unprognostic (3.06e-2)" 0.0 0.6 1.0 0.0 3.3 0.0 0.0 0.0 1.5 10.2 0.1 0.2 0.1 9.8 0.0 0.2 0.2 0.0 0.2 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 0.0 3.7 0.0 0.1 0.3 0.5 0.3 0.0 0.5 0.0 0.1 5.9 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 15.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 34.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 0.0 1.5 0.8 0.2 0.0 0.5 0.0 0.0 0.3 0.6 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 1.4 0.0 0.0 1.8 0.0 15.6 0.0 0.3 0.0 0.0 1.5 0.5 8.9 0.2 0.0 0.0 82.6 0.2 0.7 1.0 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 79.7 0.1 0.0 0.0 0.3 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 12.5 31.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.4 0.1 0.1 0.0 5.2 0.1 0.1 0.3 0.0 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTS20 GON-1 ENSG00000173157 "ADAM metallopeptidase with thrombospondin type 1 motif 20" P59510 12 43353866-43552203 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.1" "Group enriched" "Detected in some" 4 "Bipolar cells: 5.1;Inhibitory neurons: 16.1;Oligodendrocyte precursor cells: 11.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "medulla oblongata: 2.8;pons: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.6;NB-4: 1.6;NTERA-2: 2.8;SuSa: 2.2;U-266/70: 4.0;U-266/84: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027608, HPA027609" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA027608: AB_10600098, HPA027609: AB_10599024" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.04e-1)" "unprognostic (9.61e-2)" "unprognostic (3.29e-1)" "unprognostic (6.67e-2)" "unprognostic (2.26e-1)" "unprognostic (1.05e-4)" "unprognostic (7.42e-2)" "unprognostic (2.02e-1)" "unprognostic (9.81e-3)" "unprognostic (2.57e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.5 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.1 0.0 0.0 1.6 2.8 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.2 0.7 0.0 0.0 0.0 0.3 0.0 0.0 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 2.8 0.1 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Excitatory neurons: 50.2;Leydig cells: 19.9;Rod photoreceptor cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;AN3-CA: 7.8;HEL: 14.1;K-562: 12.3;SH-SY5Y: 7.0;U-2 OS: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Intermediate filaments" "HPA021368: AB_2670681, HPA021369: AB_2670682" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-3)" "unprognostic (6.11e-2)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (1.60e-3)" "unprognostic (5.92e-4)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (8.63e-3)" "unprognostic (1.65e-3)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-4)" 2.3 0.8 0.5 1.0 2.5 0.8 3.2 0.0 1.5 0.4 0.1 0.3 0.1 1.9 1.7 0.2 2.9 0.6 0.9 1.5 0.6 0.9 0.2 1.1 0.8 0.0 0.2 2.0 0.3 2.7 0.2 0.7 0.1 0.7 0.3 8.4 0.4 1.1 0.2 0.4 0.2 1.7 0.0 0.7 0.5 1.9 0.1 0.6 1.2 0.3 0.3 1.3 0.4 0.4 0.0 0.0 13.2 7.8 0.1 0.3 0.1 0.7 2.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.8 0.0 1.8 0.0 1.8 14.1 0.9 0.0 0.2 0.0 0.0 1.7 0.1 0.6 0.1 3.3 0.0 0.0 12.3 0.0 0.0 0.0 1.3 0.0 2.2 0.0 4.0 0.0 2.6 0.0 4.6 0.0 0.5 7.0 0.0 0.6 0.2 1.4 0.1 0.2 0.1 5.6 8.5 0.0 0.7 0.0 0.0 0.0 1.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.5 1.5 0.6 0.0 0.2 0.1 0.0 0.1 0.4 1.8 0.0 3.4 7.5 0.0 0.5 0.9 0.0 0.0 0.9 0.8 3.2 1.2 1.5 1.3 1.8 14.6 0.0 0.0 0.0 0.0 0.0 4.1 2.2 5.1 3.7 0.0 2.5 50.2 0.0 0.3 3.3 0.0 0.7 1.3 1.9 3.9 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.7 1.9 19.9 0.3 0.0 1.0 0.0 1.8 0.0 7.1 1.3 0.0 0.0 4.5 0.0 1.1 0.0 0.3 0.5 12.9 0.0 0.3 1.2 1.2 0.8 0.3 0.0 0.0 0.0 2.8 0.0 0.1 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 ADAMTS5 "ADAMTS11, ADMP-2" ENSG00000154736 "ADAM metallopeptidase with thrombospondin type 1 motif 5" Q9UNA0 21 26917922-26967088 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 26.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 38.2;Endometrial stromal cells: 72.1;Fibroblasts: 88.6;Leydig cells: 62.7;Skeletal myocytes: 110.2;Smooth muscle cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.9;fHDF/TERT166: 11.9;RH-30: 33.1;U-87 MG: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA005661, CAB025996, HPA030906, HPA030908" Approved Supported Nucleoplasm "Secreted to extracellular matrix" NA NA 28000 "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB025996: , HPA005661: AB_1078101, HPA030906: AB_2673654, HPA030908: AB_2673655" "unprognostic (1.97e-1)" "unprognostic (2.88e-3)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (4.67e-1)" "unprognostic (2.10e-2)" "unprognostic (4.38e-8)" "unprognostic (1.11e-3)" "unprognostic (7.66e-2)" "unprognostic (6.17e-2)" "unprognostic (8.13e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (6.69e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.15e-1)" 17.5 0.8 0.3 1.0 0.6 0.0 10.8 3.3 0.3 8.8 2.6 2.7 0.8 12.5 2.4 1.6 4.2 1.6 3.3 0.5 0.9 2.5 1.4 1.0 0.6 1.4 0.9 16.6 0.4 1.5 0.4 26.2 0.9 3.0 1.3 0.6 2.0 1.8 2.0 4.2 3.4 7.5 1.5 7.7 2.2 0.8 0.4 0.3 6.8 3.7 0.1 4.2 3.6 1.2 0.0 0.0 0.0 0.0 31.6 13.9 0.0 1.7 0.2 1.4 0.6 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.3 0.0 3.5 0.1 0.0 8.0 0.0 1.1 0.2 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 33.1 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.3 0.4 1.9 0.9 0.0 0.0 0.0 13.0 0.1 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.3 0.3 0.5 0.9 1.4 0.9 0.9 1.5 0.4 1.2 24.3 0.0 0.5 0.3 0.1 2.9 0.2 0.4 0.0 9.8 1.5 38.2 2.7 0.0 0.6 3.7 0.0 1.1 0.3 0.0 0.0 0.0 6.4 2.0 72.1 10.6 1.8 0.0 0.5 0.2 1.6 88.6 0.0 1.3 0.0 3.0 3.3 0.0 1.9 0.0 11.6 0.0 0.0 0.0 4.6 1.0 62.7 1.4 3.6 3.7 4.0 0.1 0.0 12.5 0.2 0.0 0.0 9.1 0.0 0.3 0.0 2.2 0.0 0.2 13.1 110.2 44.9 0.3 0.9 0.4 3.0 2.7 0.8 20.0 0.0 0.1 ADAMTS6 ADAM-TS6 ENSG00000049192 "ADAM metallopeptidase with thrombospondin type 1 motif 6" Q9UKP5 5 65148738-65481920 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.6;Inhibitory neurons: 63.6;Microglial cells: 31.9;Oligodendrocyte precursor cells: 139.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "BJ: 12.6;HBF TERT88: 13.4;hTEC/SVTERT24-B: 12.6;hTERT-HME1: 14.9;TIME: 14.5;U-2197: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043441 Enhanced "Secreted to extracellular matrix" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043441: AB_2678484" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.70e-3)" "unprognostic (4.33e-2)" "unprognostic (1.03e-2)" "unprognostic (2.39e-2)" "unprognostic (8.24e-2)" "unprognostic (1.65e-2)" "unprognostic (4.77e-2)" "unprognostic (8.04e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-6)" "unprognostic (3.23e-5)" "unprognostic (2.09e-1)" "unprognostic (3.02e-4)" "unprognostic (4.18e-3)" 0.5 0.1 0.2 0.6 0.2 0.0 0.3 0.2 0.3 0.3 0.5 0.3 0.1 1.1 0.7 0.2 0.6 1.4 0.3 0.2 0.6 0.2 0.0 0.5 0.4 0.3 0.4 0.3 0.0 0.0 0.1 1.9 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.6 0.6 0.3 0.7 0.3 0.5 0.3 0.2 0.1 0.1 0.3 0.7 0.3 0.2 2.7 0.0 0.6 0.6 0.0 2.0 0.0 12.6 7.4 7.7 9.0 0.0 0.3 0.0 0.1 4.8 5.3 0.5 0.1 2.4 13.4 2.0 0.0 0.2 5.1 0.3 0.4 0.0 0.7 0.9 0.0 12.6 14.9 3.7 6.9 1.3 0.0 0.0 4.8 0.0 0.7 0.0 0.1 0.3 0.1 0.4 2.6 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.0 1.6 0.0 0.1 14.5 3.0 4.5 16.2 10.2 0.1 0.0 0.0 3.4 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.4 2.1 0.1 0.2 0.0 1.3 0.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.6 0.3 0.4 0.3 0.3 0.3 0.2 11.3 0.0 0.0 4.9 16.1 0.3 0.0 0.6 0.6 13.9 0.3 0.5 1.8 1.5 0.1 3.7 0.0 34.6 3.2 0.2 0.0 1.4 15.2 8.5 7.4 13.3 0.0 0.0 16.7 0.0 4.7 5.5 0.0 25.7 1.3 18.7 8.9 0.3 2.4 0.0 63.6 0.5 2.0 0.3 1.0 8.0 12.2 3.2 0.0 31.9 0.3 17.4 1.0 139.7 2.1 2.6 0.0 18.0 2.5 0.1 0.1 1.0 0.1 1.1 6.6 5.1 10.5 6.1 8.9 0.3 0.0 14.2 5.1 2.2 0.6 0.0 ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 30.6" "Cell type enriched" "Detected in some" 4 "Theca cells: 44.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "HMC-1: 259.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045284: AB_2679285, HPA048453: AB_2680399" "unprognostic (5.94e-3)" "unprognostic (9.94e-3)" "unprognostic (2.76e-2)" "unprognostic (7.09e-2)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (5.88e-4)" "unprognostic (3.34e-3)" "unprognostic (2.89e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (8.86e-2)" 6.6 5.3 0.5 1.8 0.4 0.1 3.8 0.3 0.5 6.0 0.6 4.2 1.1 7.2 0.1 0.9 2.2 2.3 30.6 0.4 0.5 2.2 1.1 6.3 0.9 0.5 0.5 6.1 0.5 0.4 0.8 2.1 0.4 1.8 0.2 0.5 1.3 0.4 1.1 1.8 2.6 1.4 0.2 5.2 2.2 4.1 0.7 0.1 2.1 0.5 0.2 3.0 2.5 0.6 0.0 1.1 16.5 7.5 6.9 8.2 20.9 3.7 1.3 1.0 0.6 0.0 0.1 0.0 4.8 0.4 1.0 0.4 0.4 2.0 0.0 0.3 0.6 2.1 0.5 0.1 6.9 0.0 259.9 3.3 2.0 1.9 1.0 5.3 24.0 0.0 0.3 0.7 5.6 0.0 0.1 4.9 4.7 0.0 1.4 17.3 7.7 0.3 0.5 0.9 0.3 23.9 4.8 0.0 0.6 4.0 3.2 0.4 29.8 9.4 1.0 3.3 0.0 0.1 0.0 0.0 1.6 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.5 0.4 0.5 0.5 0.5 0.4 0.2 0.7 0.6 7.5 0.0 0.0 3.6 0.3 0.4 0.2 0.7 0.0 0.3 0.1 0.5 9.8 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.0 0.1 4.9 0.8 7.5 10.5 0.0 0.0 0.1 0.0 0.3 10.1 0.5 0.9 3.8 7.2 2.9 0.3 0.7 0.0 0.2 0.0 2.0 0.0 0.8 2.7 1.5 0.1 1.8 1.0 0.1 1.3 0.0 9.5 1.4 0.3 0.0 1.9 0.0 0.3 0.0 0.1 0.3 0.1 0.0 3.7 5.0 2.6 2.0 0.2 0.1 0.3 0.5 44.9 0.1 0.3 ADAMTS8 "ADAM-TS8, FLJ41712, METH2" ENSG00000134917 "ADAM metallopeptidase with thrombospondin type 1 motif 8" Q9UP79 11 130404923-130428609 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.6" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 14.5;Endometrial stromal cells: 30.9;Glandular and luminal cells: 37.7;Skeletal myocytes: 26.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.5;HeLa: 1.3;HMC-1: 4.4;NTERA-2: 2.2;U-2 OS: 9.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066349 Approved "Secreted to extracellular matrix" NA NA 3600000 "Cluster 19: Lung - Lung function" "Cluster 9: U-2 OS - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA066349: AB_2685662" "unprognostic (4.76e-6)" "unprognostic (3.92e-2)" "unprognostic (6.13e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.41e-1)" "unprognostic (7.81e-2)" "unprognostic (3.09e-2)" "unprognostic (9.83e-2)" "unprognostic (1.09e-4)" "unprognostic (3.05e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (4.66e-3)" "unprognostic (4.03e-3)" "unprognostic (5.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-1)" 1.8 0.1 1.5 10.1 2.7 0.0 0.7 0.0 3.7 2.0 0.0 7.0 1.1 3.0 1.0 3.0 2.1 1.6 2.3 3.5 0.0 0.5 0.0 27.6 0.1 0.7 0.1 0.4 0.7 0.0 0.2 2.6 0.2 2.7 0.5 0.0 0.5 4.9 0.5 0.3 2.1 4.2 0.1 0.4 5.3 0.3 1.0 0.0 0.2 0.5 0.0 4.2 0.9 1.8 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 1.3 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.7 0.0 3.7 3.5 0.0 0.7 0.1 0.2 0.1 1.0 1.8 1.3 0.0 0.6 1.0 0.0 0.4 0.4 0.1 0.0 2.4 2.3 3.9 9.1 0.0 1.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 14.5 30.9 0.6 0.0 0.0 7.4 0.0 0.0 6.6 0.0 37.7 1.3 1.3 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.7 0.5 0.0 0.1 1.8 2.8 0.0 0.1 1.0 0.5 5.9 0.0 0.0 1.5 0.0 0.5 0.0 0.1 2.6 0.2 0.0 26.9 5.7 0.1 0.3 0.1 0.1 0.0 0.6 0.1 0.0 0.0 ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 41.2" "Cell type enhanced" "Detected in many" "Adipocytes: 166.3;Astrocytes: 84.2;Basal prostatic cells: 87.2;Endometrial stromal cells: 179.1;Endothelial cells: 221.0;Prostatic glandular cells: 115.7;Smooth muscle cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 23.6;RPTEC TERT1: 27.1;SH-SY5Y: 128.3;SuSa: 40.5;WM-115: 28.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028567, HPA028577, HPA028601" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" No NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Endoplasmic reticulum" "HPA028567: AB_10599275, HPA028577: AB_10600330, HPA028601: AB_2672694" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (4.83e-2)" "unprognostic (3.08e-1)" "unprognostic (1.37e-2)" "unprognostic (7.80e-3)" "unprognostic (5.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (7.67e-2)" "unprognostic (3.16e-3)" "unprognostic (1.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-3)" "unprognostic (5.00e-3)" 41.2 4.8 4.0 12.2 5.0 0.1 19.0 5.5 5.3 16.2 7.9 8.1 1.2 13.2 1.1 5.3 10.2 7.8 15.6 4.4 5.6 9.5 2.7 13.6 1.9 10.8 8.1 7.3 9.8 6.3 2.2 31.7 8.5 7.9 2.7 1.4 3.2 3.7 7.4 2.6 3.7 12.1 8.0 4.1 4.7 0.8 8.1 1.0 7.3 7.3 1.1 22.5 9.0 6.4 0.0 1.2 13.9 0.0 0.6 0.1 1.3 0.2 0.0 0.0 0.0 1.9 0.0 0.0 2.3 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.9 0.0 8.8 2.6 0.0 0.0 0.5 0.0 23.6 0.0 0.5 0.0 0.3 0.1 0.0 0.0 7.5 1.1 0.0 0.0 2.4 0.1 27.1 0.3 0.1 128.3 0.0 0.0 0.0 40.5 0.0 0.7 5.4 0.8 0.4 0.0 0.8 0.0 0.0 0.0 0.5 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.0 5.5 5.3 4.4 5.6 10.8 8.1 8.5 8.0 8.1 6.4 166.3 3.2 4.8 84.2 0.0 17.5 87.2 0.0 4.6 0.0 6.9 15.9 6.6 2.8 2.6 38.6 2.1 1.0 0.2 1.1 0.0 69.7 0.9 13.2 179.1 221.0 1.2 0.0 4.2 3.3 0.6 31.4 1.5 33.8 0.0 8.4 27.1 0.3 7.5 0.0 14.3 1.1 0.0 0.3 20.1 0.4 2.5 2.7 26.6 21.5 0.0 0.2 0.0 26.7 0.6 45.5 1.0 2.2 0.0 115.7 0.0 10.8 0.1 0.1 0.0 20.7 94.8 0.3 0.7 1.3 13.5 1.6 3.2 12.1 0.9 36.7 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Endothelial cells: 5.7;Fibroblasts: 8.5;Microglial cells: 12.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 7.4;RPMI-8226: 10.1;SH-SY5Y: 30.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" 3.7 28.5 6.8 1.0 7.3 0.1 1.5 12.0 10.1 2.3 1.4 2.7 1.4 3.1 3.1 1.8 3.1 2.5 73.2 5.8 7.9 25.9 35.8 23.2 3.4 19.3 11.1 4.9 7.1 1.2 15.9 1.5 20.8 8.4 0.3 0.3 3.4 2.2 4.3 0.8 3.2 0.9 8.5 6.4 2.3 3.1 9.3 0.6 12.1 0.5 0.6 5.3 1.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.5 0.0 1.1 0.7 10.1 0.0 0.0 1.4 30.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.3 12.0 10.1 5.8 7.9 19.3 11.1 20.8 8.5 9.3 7.6 1.4 0.0 0.5 4.9 0.1 0.1 0.1 0.0 0.0 4.2 0.0 0.1 2.3 0.0 0.0 1.8 0.0 0.1 0.0 1.4 5.9 0.2 0.1 0.1 0.1 5.7 5.3 0.0 5.0 0.0 0.1 8.5 0.0 0.0 0.0 0.1 4.6 0.9 0.3 0.0 3.8 0.4 0.0 0.3 0.8 1.1 4.7 0.6 0.0 12.2 0.0 0.4 0.0 2.5 4.0 0.2 0.5 3.0 0.0 0.2 0.0 0.7 0.0 0.2 6.6 1.1 1.6 0.1 0.8 0.4 0.3 0.0 0.6 0.7 1.1 0.2 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.7;Endometrial stromal cells: 36.9;Extravillous trophoblasts: 46.4;Fibroblasts: 34.5;Hofbauer cells: 34.0;Syncytiotrophoblasts: 99.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 11.1" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 92.0;BEWO: 200.3;HSkMC: 43.8;K-562: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" 32.0 5.1 1.1 14.9 1.0 4.2 24.7 0.8 11.1 22.9 7.9 19.3 3.6 20.0 1.6 33.3 29.2 7.7 22.3 0.8 1.4 6.4 17.3 26.1 1.8 4.4 2.8 17.1 3.0 0.5 3.0 62.9 2.9 9.0 3.8 0.6 11.8 3.4 37.7 11.8 13.7 11.4 1.2 5.4 17.2 2.4 3.6 0.8 6.1 47.9 1.2 32.8 23.3 1.5 22.0 0.6 0.3 3.9 19.1 92.0 200.3 20.8 18.0 12.1 7.0 1.8 8.5 0.2 4.3 14.4 0.2 11.0 0.8 3.2 4.9 1.7 0.4 6.2 2.6 8.9 15.3 0.3 3.0 43.8 0.9 3.0 6.8 10.3 0.1 0.0 67.7 0.7 2.2 0.5 0.0 1.1 3.5 0.6 0.7 0.0 0.0 0.1 2.1 0.8 0.1 0.6 6.7 15.9 0.1 10.0 4.5 11.5 3.8 0.7 5.5 8.6 0.3 1.9 0.6 4.5 0.8 4.0 0.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.3 1.1 1.0 0.8 11.1 0.8 1.4 4.4 2.8 2.9 1.2 3.6 1.5 2.8 0.0 1.5 1.0 0.5 2.4 2.3 0.2 0.6 1.7 1.3 1.8 2.2 10.0 0.6 0.0 0.0 146.7 1.0 0.2 0.0 1.7 0.6 2.6 36.9 5.3 0.0 0.0 0.3 0.6 46.4 34.5 0.0 5.4 2.5 0.9 1.8 10.6 34.0 0.0 0.1 0.2 0.0 24.0 12.5 0.7 30.1 20.0 3.6 0.0 23.1 1.4 1.0 0.0 0.0 12.3 0.1 3.4 3.2 2.2 0.0 0.2 0.9 2.2 0.0 14.3 3.8 0.1 1.6 5.5 2.8 99.5 1.7 0.5 0.3 2.5 ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 9.8;Cardiomyocytes: 9.6;Leydig cells: 19.3;Peritubular cells: 18.0;Proximal enterocytes: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA044050: AB_10962625" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (5.85e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-3)" 1.8 1.5 1.7 0.7 2.2 0.3 2.2 2.3 2.0 33.0 8.3 3.2 9.8 19.8 5.0 15.1 9.5 0.5 20.7 1.8 0.4 1.5 4.2 1.4 0.6 0.8 1.0 1.3 1.0 1.4 2.6 4.2 0.6 4.5 1.1 0.9 3.9 3.3 15.1 2.1 8.4 12.5 0.2 0.8 1.4 3.6 1.6 0.2 1.5 5.9 1.5 3.8 22.5 1.4 8.1 3.5 0.1 0.1 4.1 3.0 3.8 14.7 9.8 5.6 8.1 20.7 4.0 0.0 3.6 12.3 1.6 6.7 3.5 4.2 4.2 7.9 0.4 1.7 11.0 3.8 4.6 0.2 10.2 1.8 4.6 1.3 3.5 7.4 0.0 2.5 5.0 9.8 0.6 7.5 0.4 0.4 0.1 2.3 1.8 0.2 0.8 2.1 4.5 0.0 0.1 0.3 3.5 0.4 4.4 1.9 9.2 3.0 0.9 0.0 5.4 10.9 0.6 6.2 4.2 1.0 0.1 0.8 2.4 0.2 0.0 0.4 1.4 0.5 0.9 0.0 1.6 1.1 0.0 0.0 2.0 1.3 0.1 0.0 0.9 0.0 0.5 0.5 1.7 2.2 2.3 2.0 1.8 0.4 0.8 1.0 0.6 0.2 1.6 1.4 0.2 0.0 1.1 3.6 0.3 0.4 2.4 9.8 6.2 0.3 1.9 0.8 9.6 0.0 3.4 0.0 0.0 0.8 0.7 0.6 0.0 0.6 0.6 0.3 4.5 0.4 0.0 0.0 0.1 1.7 2.1 5.8 1.1 0.4 0.0 0.5 0.0 1.8 0.3 0.0 0.1 1.8 4.1 0.0 0.4 2.6 19.3 0.4 1.8 1.0 0.0 3.7 0.0 0.0 0.1 7.0 1.5 18.0 1.8 2.7 12.5 0.5 1.3 2.1 0.0 0.9 3.3 0.6 1.9 8.4 0.4 0.7 1.2 0.3 1.6 3.5 ADCK1 FLJ39600 ENSG00000063761 "AarF domain containing kinase 1" Q86TW2 14 77800109-77935014 "Enzymes, Predicted secreted proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9;Oligodendrocytes: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051012, HPA055014" Uncertain Uncertain Nucleoplasm "Secreted - unknown location" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA051012: AB_2681310, HPA055014: AB_2682672" "unprognostic (6.36e-2)" "unprognostic (7.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.70e-4)" "prognostic favorable (4.11e-5)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (4.57e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.82e-6)" "unprognostic (6.30e-3)" "unprognostic (2.06e-1)" "unprognostic (9.57e-2)" "unprognostic (4.06e-1)" 4.4 8.1 7.3 3.7 7.8 5.3 4.2 7.3 10.3 4.3 8.2 6.7 7.4 4.8 5.1 6.1 4.4 3.8 9.0 7.8 7.2 7.0 8.6 4.0 4.1 7.8 7.4 4.7 6.7 6.5 8.3 5.1 8.2 6.5 5.8 3.8 6.7 5.4 8.9 6.3 5.6 6.4 7.1 7.3 6.1 4.6 7.9 5.2 5.9 5.2 4.8 5.1 4.0 10.2 5.5 9.1 4.4 17.4 13.0 6.5 6.2 5.7 7.9 4.5 5.6 4.7 12.4 12.0 8.5 9.5 7.5 10.2 27.0 9.3 2.9 6.3 9.1 2.8 4.9 7.5 12.2 4.5 6.6 7.7 16.2 1.9 5.7 4.4 7.1 10.1 11.4 7.4 5.9 24.5 5.8 7.6 9.6 17.5 10.2 9.1 0.7 9.0 6.6 13.9 10.4 6.0 10.6 14.7 5.9 6.8 20.9 9.4 6.8 4.6 3.4 8.9 4.6 6.4 7.7 6.3 6.6 7.7 5.8 1.3 4.0 1.4 4.2 6.0 2.9 1.4 1.6 2.4 7.4 3.0 1.9 3.4 0.3 3.2 2.5 5.5 3.1 2.5 7.3 7.8 7.3 10.3 7.8 7.2 7.8 7.4 8.2 7.1 7.9 10.2 1.9 0.0 3.7 10.1 1.8 0.9 1.8 3.9 2.8 5.9 2.9 3.0 5.7 4.3 2.8 0.0 20.9 8.2 4.2 4.0 3.9 4.4 1.5 2.0 2.4 1.4 1.8 2.1 10.3 5.1 4.2 2.4 6.6 2.4 1.3 5.0 1.8 6.6 9.6 8.4 11.7 4.0 4.1 4.4 1.5 0.8 1.5 5.1 0.0 5.6 2.5 4.0 3.1 11.6 29.0 2.8 1.3 1.9 3.2 1.5 3.0 3.8 2.4 9.3 0.0 2.1 1.6 1.8 9.9 4.3 1.4 5.3 2.2 4.6 5.4 1.2 ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904871-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.9;lymphoid tissue: 10.9" "Group enriched" "Detected in some" 6 "Excitatory neurons: 13.4;granulocytes: 43.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SCLC-21H: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065887 Supported Supported "Secreted in other tissues" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA065887: " "unprognostic (2.68e-1)" "unprognostic (1.83e-2)" "unprognostic (7.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.87e-4)" "unprognostic (9.58e-3)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (6.86e-2)" "unprognostic (4.16e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.91e-6)" "unprognostic (2.24e-3)" "unprognostic (9.22e-2)" "unprognostic (1.74e-1)" "unprognostic (5.74e-4)" 1.8 0.2 1.9 10.9 2.6 0.0 1.3 0.3 2.9 2.1 0.0 1.8 0.1 3.0 0.0 1.3 0.4 7.1 0.5 2.7 21.7 0.5 0.2 1.6 1.0 31.9 6.8 0.1 4.8 0.2 3.5 0.1 13.7 1.4 1.1 0.3 1.9 0.5 0.2 0.7 1.3 1.0 5.4 0.1 1.5 2.5 17.7 0.4 0.2 0.0 1.0 2.3 1.3 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.6 0.3 2.9 2.7 21.7 31.9 6.8 13.7 5.4 17.7 2.0 0.2 3.2 0.6 0.3 0.0 0.6 0.1 0.1 0.0 0.5 0.1 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.0 13.4 0.0 0.0 2.4 0.0 0.0 43.1 0.0 0.4 0.0 0.1 0.0 0.5 0.0 4.1 0.0 0.9 1.5 0.3 0.2 0.0 1.9 0.0 0.2 0.0 0.5 1.1 2.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 2.6 0.0 0.0 0.4 0.0 2.0 0.0 0.0 0.2 ADGRB1 BAI1 ENSG00000181790 "Adhesion G protein-coupled receptor B1" O14514 8 142449430-142545009 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity, Myogenesis, Neurogenesis, Phagocytosis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 37.3" "Cell type enhanced" "Detected in some" "Astrocytes: 58.8;Excitatory neurons: 47.5;Horizontal cells: 126.2;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 70.9" "Cancer enriched" "Detected in many" 5 "glioma: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 12.1;MCF7: 4.6;NB-4: 6.1;RPMI-8226: 17.5;U-2 OS: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (9.57e-4)" "unprognostic (1.28e-1)" "unprognostic (3.87e-3)" "unprognostic (8.50e-3)" "unprognostic (9.98e-2)" "unprognostic (5.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.14e-2)" "unprognostic (2.76e-1)" "unprognostic (2.55e-1)" "unprognostic (6.48e-2)" "unprognostic (3.43e-1)" "unprognostic (7.30e-11)" "unprognostic (6.27e-2)" "unprognostic (7.42e-2)" "unprognostic (4.52e-3)" "unprognostic (3.29e-2)" 0.6 1.8 21.7 0.3 17.7 0.1 0.6 0.8 37.3 2.9 0.0 0.8 0.3 1.2 0.7 0.7 0.8 0.1 0.5 18.6 13.7 0.7 0.2 0.8 0.4 12.9 9.4 1.3 0.4 1.6 6.4 0.9 13.1 1.5 0.0 1.6 0.9 0.5 0.1 5.0 1.1 0.1 1.2 2.5 0.8 1.9 24.0 0.2 0.6 0.1 0.1 0.4 1.3 5.4 0.0 0.1 0.1 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.9 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 6.1 1.9 0.2 0.0 0.1 0.0 17.5 0.0 0.0 3.2 3.2 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.1 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 17.7 0.8 37.3 18.6 13.7 12.9 9.4 13.1 1.2 24.0 5.4 0.1 0.0 0.0 58.8 0.3 0.0 0.6 0.0 1.8 18.5 1.3 0.8 5.7 1.5 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.3 0.2 0.0 0.1 0.4 0.0 0.0 47.5 0.0 0.0 0.8 0.5 0.0 0.0 0.2 0.0 0.0 0.1 126.2 38.0 0.1 0.0 0.3 0.0 1.0 0.3 0.3 0.0 9.4 0.8 3.9 0.0 70.9 2.6 0.1 0.1 13.5 0.0 0.2 0.0 0.2 0.0 0.9 6.6 0.4 0.4 0.0 0.8 0.1 0.0 0.0 0.3 0.3 0.1 0.2 ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.1;lymphoid tissue: 6.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.4;Astrocytes: 2.0;Excitatory neurons: 1.9;granulocytes: 2.5;Inhibitory neurons: 2.4;Macrophages: 8.0;Microglial cells: 3.7;monocytes: 3.2;Oligodendrocytes: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 281.6;eosinophil: 509.0;neutrophil: 489.4" "Lineage enriched" "Detected in many" 8 "granulocytes: 509.0" "Cell line enriched" "Detected in some" 36 "HMC-1: 43.3" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA015638: AB_1848039" "unprognostic (2.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (9.61e-2)" "unprognostic (9.11e-4)" "unprognostic (4.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" 1.2 0.1 0.0 6.1 0.0 3.1 0.0 0.0 0.5 0.2 0.0 0.4 1.6 0.1 0.0 0.3 0.3 1.0 0.1 0.0 0.0 0.1 0.6 2.5 0.3 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.2 0.2 0.5 0.0 1.8 0.0 0.0 0.0 2.3 0.7 0.0 5.9 0.5 0.1 0.1 0.4 0.1 1.0 2.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 281.6 21.8 509.0 0.0 52.9 0.1 0.6 0.2 0.0 5.3 0.1 0.1 0.1 489.4 0.0 61.3 0.3 0.1 7.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 2.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.5 0.0 2.5 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.6 0.0 0.0 0.0 8.0 0.0 3.7 3.2 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 211.6" "Cell type enhanced" "Detected in many" "dendritic cells: 245.4;Kupffer cells: 111.1;Macrophages: 131.6;NK-cells: 160.6;Plasma cells: 141.5;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved Cytosol "Secreted to blood" NA Yes 10000000 2400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" 45.6 21.4 4.7 79.5 7.6 211.6 21.5 7.8 6.3 60.9 4.0 52.7 43.6 143.6 7.0 15.1 48.9 33.2 30.4 4.8 6.0 28.0 19.9 80.2 58.2 9.6 7.4 14.6 31.4 6.1 7.5 32.7 8.4 17.0 29.7 0.4 22.1 10.4 29.5 14.9 51.0 75.3 6.6 145.0 40.5 3.4 9.0 32.5 21.3 13.5 32.0 42.2 29.3 12.1 118.1 81.9 0.8 77.2 33.3 54.1 12.2 79.6 127.0 56.0 61.0 23.5 115.9 13.5 78.5 103.1 79.6 27.2 21.0 38.8 25.0 73.4 23.7 26.4 113.0 10.4 41.0 57.4 117.3 23.9 1.0 57.1 19.4 18.2 5.6 22.7 35.0 101.9 61.9 26.6 3.7 76.3 2.3 92.7 100.4 7.8 33.7 61.8 18.7 10.4 1.0 2.8 45.4 64.1 57.9 1.8 16.7 52.3 14.0 19.0 31.1 79.5 133.2 0.2 0.4 1.1 67.6 100.4 72.0 371.6 158.5 772.8 187.5 281.4 123.9 28.5 94.2 129.6 102.6 18.5 65.5 91.9 623.2 179.2 352.9 48.4 70.6 242.4 4.7 7.6 7.8 6.3 4.8 6.0 9.6 7.4 8.4 6.6 9.0 12.1 10.0 35.3 93.1 1.3 88.6 0.0 8.5 0.0 2.2 0.5 7.2 6.7 3.7 12.8 17.3 0.0 0.0 4.1 245.4 25.8 0.0 18.1 0.1 16.1 26.9 13.1 4.9 25.7 1.4 22.5 46.3 20.0 49.5 13.3 77.0 1.4 23.9 2.9 50.8 0.0 1.8 25.9 0.0 111.1 0.0 1.4 6.5 131.6 0.0 6.5 55.3 2.6 160.6 2.0 11.2 21.2 30.6 4.9 141.5 12.8 17.8 0.9 27.7 1.5 26.3 34.6 23.1 0.5 5.3 3.2 0.0 7.9 184.3 3.7 29.1 17.6 ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.5;kidney: 20.3;urinary bladder: 42.6" "Group enriched" "Detected in some" 4 "Collecting duct cells: 108.5;Pancreatic endocrine cells: 98.9;Urothelial cells: 363.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 31.2;CAPAN-2: 113.3;HaCaT: 25.3;PC-3: 36.6;RPTEC TERT1: 50.9;RT4: 132.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 3.4 0.0 0.3 0.0 0.2 0.1 17.5 0.8 6.1 0.0 0.0 0.0 20.3 0.0 3.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 3.0 0.1 0.0 3.2 1.7 0.0 0.0 3.2 0.0 0.0 0.0 1.4 0.6 0.0 0.1 6.2 0.0 5.9 42.6 6.4 0.0 31.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.3 0.0 2.0 0.0 0.0 25.3 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.5 36.6 0.0 0.0 0.0 50.9 132.6 0.0 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 21.8 0.0 0.1 0.0 25.4 0.0 0.6 0.0 5.5 1.9 0.7 12.8 13.6 108.5 0.0 0.0 0.0 1.5 23.5 30.8 0.0 7.0 5.0 0.7 0.0 0.0 0.1 18.9 0.1 0.8 3.6 46.9 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.9 0.0 0.0 0.0 39.1 1.2 0.7 14.6 0.0 0.0 0.2 1.1 0.0 0.2 2.6 0.0 0.1 1.0 0.1 0.2 363.7 ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 216.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.5;Exocrine glandular cells: 170.7;NK-cells: 208.1;Syncytiotrophoblasts: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.3" "Lineage enriched" "Detected in many" 5 "T-cells: 160.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 218.4;SK-BR-3: 277.7;SK-MEL-30: 297.8;TIME: 241.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" NA NA 32000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" 50.9 13.2 79.6 12.7 67.7 19.6 50.5 46.9 115.2 36.3 0.0 36.7 26.1 19.7 84.2 46.7 52.2 69.6 36.8 68.7 71.5 158.9 4.2 37.3 5.2 64.6 76.2 5.3 59.8 28.4 17.7 101.3 73.9 31.7 33.4 6.6 92.2 57.5 15.7 87.5 19.3 19.8 54.8 12.3 47.9 45.4 92.5 28.9 216.3 16.9 15.6 37.1 37.8 51.6 41.8 47.1 12.0 0.6 0.0 0.1 127.7 8.5 3.9 14.4 2.6 34.7 218.4 0.2 110.5 8.2 196.1 149.1 0.0 103.4 5.1 1.6 0.0 5.1 56.0 39.3 0.3 0.4 2.1 2.4 143.8 24.5 10.2 15.8 118.1 1.0 0.1 1.2 3.2 51.4 107.3 0.8 1.7 143.3 42.6 3.8 1.4 30.8 209.4 134.9 38.2 1.2 2.0 277.7 297.8 8.4 123.8 0.8 241.4 25.6 38.0 1.5 96.2 0.2 2.1 0.6 200.5 0.7 62.9 2.9 0.8 0.2 160.3 0.5 1.9 0.3 10.5 62.6 0.2 0.1 5.3 45.2 3.3 30.6 0.7 0.3 0.2 37.1 79.6 67.7 46.9 115.2 68.7 71.5 64.6 76.2 73.9 54.8 92.5 51.6 107.7 9.6 11.9 113.9 3.7 0.0 24.1 0.0 11.4 0.9 29.6 27.2 4.3 15.7 21.7 79.1 0.0 222.5 120.4 17.7 27.4 33.9 74.0 24.6 4.3 53.9 20.6 17.7 3.5 170.7 25.1 4.7 29.0 45.2 5.1 88.2 30.0 0.5 22.8 0.0 4.9 23.2 0.0 3.5 0.0 31.3 3.1 6.1 0.0 41.2 1.1 4.8 208.1 85.5 1.3 101.1 12.3 0.0 19.1 15.2 5.6 132.6 16.8 0.5 0.0 1.6 7.1 2.7 0.9 23.0 0.0 186.5 35.1 0.4 24.6 19.5 ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "adipose tissue: 898.8;breast: 248.9" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 672 "ASC diff: 312.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" NA NA 8360000000 910000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB046467: AB_1078104, HPA051767: AB_2681598" "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" 898.8 8.9 0.1 2.4 0.1 0.2 248.9 0.2 0.1 0.0 0.0 7.7 0.1 0.1 0.0 1.2 0.1 7.6 6.5 0.0 0.0 0.8 0.1 0.1 1.3 0.1 0.0 0.0 6.2 0.1 0.1 0.0 0.1 0.3 6.1 0.1 18.8 0.0 2.3 6.6 8.5 1.2 0.0 0.0 3.9 0.1 0.1 2.2 2.9 20.2 0.0 2.4 0.9 0.3 0.0 0.0 0.0 0.1 312.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADM AM ENSG00000148926 Adrenomedullin P35318 11 10305073-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 340.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 590.8;Extravillous trophoblasts: 1217.1;Syncytiotrophoblasts: 1084.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "neutrophil: 242.2" "Lineage enriched" "Detected in many" 18 "granulocytes: 242.2" "Cell line enhanced" "Detected in many" "ASC diff: 684.6;fHDF/TERT166: 357.4;HSkMC: 410.9;U-138 MG: 390.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016075, HPA068955" Approved "Secreted to blood" NA NA 31000 340000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016075: AB_628693, HPA068955: " "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (1.55e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (8.13e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.33e-4)" "unprognostic (9.70e-3)" "unprognostic (2.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.62e-2)" 340.2 29.9 12.9 32.2 18.3 43.9 195.9 28.1 15.2 162.1 17.9 60.6 8.0 20.3 3.1 84.6 71.0 30.0 153.3 10.6 15.5 123.8 90.5 157.6 17.1 19.7 18.0 33.1 24.6 23.5 43.3 102.8 16.5 26.8 11.4 16.7 52.7 1.6 79.3 169.8 49.5 7.6 16.8 34.5 55.5 4.9 21.6 4.1 52.7 14.3 3.5 85.1 224.3 18.6 35.4 29.2 33.8 9.8 684.6 306.7 51.8 263.6 263.9 260.5 175.7 142.4 43.9 0.1 11.7 357.4 136.9 51.0 9.5 40.6 191.9 0.7 13.9 1.1 16.1 18.0 88.0 1.6 1.1 410.9 34.7 30.8 44.6 89.9 60.4 0.5 0.4 0.7 64.3 1.2 0.2 10.6 65.7 8.4 13.6 1.0 1.1 54.5 16.7 48.6 1.1 3.2 101.0 23.7 0.6 36.4 31.4 0.3 17.9 390.0 5.5 233.2 37.9 2.7 29.5 10.5 112.0 0.2 117.0 0.0 7.0 0.0 0.0 7.7 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.1 242.2 0.0 13.6 0.0 0.3 1.9 12.9 18.3 28.1 15.2 10.6 15.5 19.7 18.0 16.5 16.8 21.6 18.6 347.7 9.6 12.3 17.0 14.2 192.1 590.8 194.4 182.1 2.7 28.0 46.9 104.6 18.6 136.2 3.7 8.4 134.6 9.1 266.7 15.6 135.7 0.5 80.8 58.1 99.1 67.5 4.0 0.4 30.5 1217.1 202.8 55.0 210.9 9.5 30.1 95.7 18.6 71.4 3.3 3.0 127.6 181.0 69.6 57.7 2.6 132.7 107.9 40.9 6.5 8.1 4.9 1.0 1.5 0.1 61.7 298.3 19.2 20.0 218.9 14.0 60.1 38.7 15.3 0.0 73.3 76.5 5.1 4.9 182.3 125.6 1084.8 14.7 8.1 55.5 224.5 ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.3;pancreas: 15.5;thyroid gland: 11.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 10.0;Gastric mucus-secreting cells: 7.1;Intestinal goblet cells: 7.1;Pancreatic endocrine cells: 9.4;Proximal enterocytes: 7.4;Proximal tubular cells: 28.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 37.1;hTCEpi: 23.8;Karpas-707: 38.2;SK-MEL-30: 25.9;U-266/70: 25.6" "Not detected" "Not detected" "Secreted to blood" NA NA 61300 "Cluster 25: Pancreas - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.30e-2)" "unprognostic (4.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-1)" "unprognostic (4.62e-3)" "unprognostic (7.26e-3)" "unprognostic (1.50e-1)" "unprognostic (3.44e-1)" "unprognostic (7.20e-2)" "unprognostic (9.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.06e-2)" 0.3 0.2 0.2 1.7 0.3 0.4 0.4 0.6 0.4 0.9 0.0 1.1 3.7 0.1 1.7 3.0 0.2 1.2 0.1 0.1 0.1 8.3 3.8 0.8 2.6 0.2 0.2 0.0 15.5 0.3 0.4 0.2 0.2 2.6 0.6 0.0 5.6 0.4 0.0 0.4 2.9 0.2 0.0 1.1 4.0 0.6 0.4 1.0 11.6 0.0 1.9 0.3 0.3 0.2 1.8 0.3 0.5 2.0 1.2 2.1 7.0 9.1 0.8 1.3 2.9 3.9 1.5 0.0 1.3 7.9 1.5 1.4 2.0 1.2 0.5 17.3 0.0 0.1 0.5 2.8 37.1 3.8 2.5 7.5 23.8 4.1 8.6 0.1 0.1 10.1 2.4 38.2 0.3 5.8 0.3 0.7 1.2 10.7 5.7 0.0 0.0 15.1 1.7 0.2 1.0 4.0 0.1 5.5 25.9 1.2 7.6 12.2 0.0 0.0 8.1 0.0 0.0 25.6 4.2 5.0 0.3 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.1 0.1 0.2 0.2 0.2 0.0 0.4 0.2 0.2 0.0 3.0 0.0 2.5 0.0 0.9 1.0 0.0 0.0 3.6 1.8 1.4 1.5 0.5 0.0 0.0 0.1 0.6 3.9 3.9 2.6 0.0 0.5 0.4 0.3 1.2 0.0 0.0 10.0 0.7 0.2 7.1 1.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 7.1 0.0 0.0 0.3 0.2 0.0 0.4 1.8 0.0 0.6 0.0 1.0 0.0 0.0 9.4 1.4 0.0 3.1 2.0 7.4 28.1 0.1 0.0 0.0 1.1 0.7 0.2 1.0 0.0 0.4 1.0 1.2 0.0 1.1 0.9 ADM5 "AM5, C19orf76" ENSG00000224420 "Adrenomedullin 5 (putative)" C9JUS6 19 49688664-49690575 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 29.3;Endothelial cells: 47.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 18.0" "Secreted to blood" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.34e-2)" "unprognostic (2.56e-1)" "unprognostic (3.08e-3)" "unprognostic (5.62e-2)" "unprognostic (2.18e-2)" "unprognostic (2.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.39e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (1.47e-2)" "unprognostic (8.94e-2)" "unprognostic (4.21e-11)" "unprognostic (2.39e-2)" "unprognostic (9.25e-2)" "unprognostic (9.92e-3)" "prognostic favorable (6.74e-4)" 7.8 0.8 1.9 0.7 1.9 1.3 6.0 4.5 2.9 3.7 1.5 2.4 0.8 4.3 0.3 3.3 5.0 0.6 1.8 2.0 1.9 3.5 1.8 4.3 1.0 1.9 1.9 2.0 1.8 0.1 2.7 0.7 2.2 3.9 0.2 1.5 2.6 0.4 3.9 5.0 2.9 0.8 1.8 6.7 2.3 3.0 2.2 0.7 2.6 0.4 0.7 3.6 3.6 1.9 3.4 5.7 3.3 2.3 0.1 0.0 3.9 0.3 0.3 1.1 0.6 6.6 3.1 5.1 1.2 0.2 0.3 1.0 5.9 1.9 0.4 6.0 11.3 5.8 1.6 4.3 0.1 1.7 3.8 0.6 4.2 0.7 0.5 0.8 1.1 5.4 4.2 3.7 0.2 5.4 2.6 18.0 4.4 0.6 1.6 7.4 2.5 5.3 0.5 5.9 2.0 0.9 0.8 1.6 1.6 0.8 3.6 2.5 0.9 1.8 6.6 0.9 1.4 12.6 10.7 5.9 1.2 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 4.5 2.9 2.0 1.9 1.9 1.9 2.2 1.8 2.2 1.9 29.3 0.0 1.5 1.3 1.4 6.1 1.4 1.4 6.2 4.3 5.4 6.1 0.1 1.5 1.5 0.0 0.0 0.5 1.0 1.8 0.0 0.5 8.1 3.0 1.9 47.3 1.2 0.0 0.3 1.1 0.5 2.2 1.5 6.0 0.0 0.7 5.0 0.3 0.3 0.0 0.4 1.5 0.0 1.0 4.9 4.3 0.6 1.3 5.4 0.0 0.2 0.9 0.0 0.0 0.9 0.6 0.4 0.7 0.2 1.9 0.3 0.0 1.6 2.4 0.0 2.9 1.5 1.1 1.2 6.2 6.3 0.1 1.3 0.3 1.6 1.1 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AFM "ALB2, ALBA" ENSG00000079557 Afamin P43652 4 73481745-73504001 "Plasma proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 961.6" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 300.4" "Cancer enriched" "Detected in single" 167 "liver cancer: 62.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "CACO-2: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017006, HPA052437" Enhanced "Secreted to blood" NA NA 54900000000 8700000000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA017006: AB_1844635, HPA052437: AB_2732575" "prognostic favorable (1.80e-4)" "unprognostic (5.73e-2)" "unprognostic (4.24e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 79.7 961.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.2 4.3 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.2 300.4 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.0 AFP "FETA, HPAFP" ENSG00000081051 "Alpha fetoprotein" P02771 4 73431138-73456174 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 3.7" "Group enriched" "Detected in some" 10 "Hepatocytes: 107.5;Proximal tubular cells: 101.6" "Cancer enriched" "Detected in some" 4 "liver cancer: 208.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 192 "Hep G2: 2165.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010607, HPA023600, CAB024283, CAB025339" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 3010000 150000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "CAB024283: AB_2650473, CAB025339: , HPA010607: AB_1078141, HPA023600: AB_1844769" "unprognostic (4.69e-1)" "unprognostic (1.87e-1)" "unprognostic (3.34e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-3)" "unprognostic (2.95e-2)" "unprognostic (3.35e-1)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-6)" "unprognostic (1.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 1.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 9.7 5.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 7.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 2.7 2.8 0.3 0.0 0.1 0.0 0.1 2.5 107.5 2.3 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 101.6 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 1.5 0.2 0.1 0.2 0.0 AGER "RAGE, SCARJ1" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lung: 728.3" "Cell type enriched" "Detected in many" 22 "Alveolar cells type 1: 2394.2" "Cancer enhanced" "Detected in all" "lung cancer: 27.2;thyroid cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.5;JURKAT: 3.0;RPTEC TERT1: 2.2;U-266/70: 2.4;U-266/84: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" NA NA 5360000 100000 "Cluster 19: Lung - Lung function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: AB_2258049, HPA064436: AB_2685264, HPA069474: " "unprognostic (9.37e-2)" "unprognostic (3.70e-1)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.01e-7)" "unprognostic (3.57e-1)" "unprognostic (3.70e-2)" "unprognostic (4.44e-2)" "prognostic favorable (2.74e-6)" 2.2 1.7 0.1 1.1 0.1 0.5 1.6 0.1 0.4 4.4 0.2 3.9 0.6 2.5 1.9 2.1 4.5 0.1 2.7 0.2 0.1 6.4 2.7 728.3 0.6 0.2 0.1 4.8 1.7 0.0 5.0 0.4 0.2 4.9 0.8 0.4 1.6 0.0 1.0 2.0 3.2 0.1 0.1 7.0 2.0 2.2 0.2 0.8 39.2 0.1 0.5 2.9 3.2 0.3 0.1 0.0 0.0 0.3 0.1 0.9 1.5 0.0 0.1 0.0 0.1 0.0 0.2 0.1 1.0 0.2 0.0 1.0 0.1 0.3 0.2 0.2 2.5 0.7 0.0 0.0 0.0 0.3 1.1 0.0 0.1 0.0 0.1 0.2 0.1 3.0 0.0 0.3 0.1 1.3 0.1 0.9 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.5 0.0 0.1 0.0 0.6 0.8 0.1 2.4 2.0 0.9 1.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 5.4 2394.2 107.9 5.9 4.9 0.9 1.5 2.0 2.8 5.1 1.5 2.9 3.0 4.3 20.9 1.8 0.0 1.1 2.7 1.1 0.0 1.5 0.4 1.1 2.6 4.1 0.0 4.4 0.5 1.0 0.9 3.0 1.5 1.9 17.7 3.1 2.9 2.0 1.3 6.7 0.6 1.3 0.0 5.3 6.5 1.2 1.8 5.3 1.8 4.7 4.8 4.6 2.1 2.5 1.3 1.1 2.7 1.2 3.3 2.6 0.8 0.3 5.6 3.4 6.6 1.2 2.6 0.1 1.2 1.6 1.8 2.2 6.2 1.7 1.2 0.9 AGGF1 "FLJ10283, GPATC7, GPATCH7, HSU84971, VG5Q" ENSG00000164252 "Angiogenic factor with G-patch and FHA domains 1" Q8N302 5 77029251-77065234 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "unprognostic (7.13e-2)" "unprognostic (1.04e-1)" "prognostic favorable (2.87e-4)" "unprognostic (1.67e-1)" "unprognostic (1.82e-1)" "unprognostic (6.52e-2)" "unprognostic (1.12e-3)" "unprognostic (4.27e-2)" "unprognostic (2.02e-2)" "unprognostic (4.03e-2)" "unprognostic (1.82e-2)" "unprognostic (4.04e-1)" "unprognostic (1.58e-3)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "unprognostic (8.21e-2)" 9.8 10.5 11.0 11.5 11.1 9.2 10.5 11.2 11.8 9.1 9.5 10.5 14.1 9.1 21.4 8.7 7.7 8.6 10.0 11.1 11.3 12.9 13.7 9.4 13.6 12.0 12.0 10.6 8.1 16.0 6.1 10.9 12.1 9.7 11.5 22.3 8.6 8.8 13.0 12.5 13.3 8.9 11.0 12.6 10.1 16.2 12.4 14.4 11.0 11.1 14.1 9.4 6.6 13.1 21.6 14.5 18.4 23.2 20.8 21.5 17.9 17.7 18.8 12.9 16.3 9.6 23.2 14.4 21.7 12.4 22.6 19.2 9.9 18.1 20.0 21.9 17.2 14.6 16.8 13.2 15.6 15.6 22.8 15.3 22.0 13.3 15.3 17.4 15.9 21.4 17.7 11.9 18.5 21.6 27.3 15.7 0.0 9.0 10.4 21.5 30.2 34.1 21.9 17.1 18.5 22.5 19.0 14.7 21.9 15.8 28.3 20.1 15.2 11.6 14.6 19.1 20.5 23.5 28.6 3.3 21.1 24.5 22.0 17.5 14.0 28.9 14.8 12.6 11.8 13.2 13.6 13.8 13.0 13.5 15.8 13.2 12.7 14.9 12.6 14.3 15.8 9.7 11.0 11.1 11.2 11.8 11.1 11.3 12.0 12.0 12.1 11.0 12.4 13.1 9.0 28.9 21.7 22.5 28.2 7.1 16.9 20.4 39.3 49.2 9.2 9.0 45.0 22.8 10.0 5.5 35.5 29.5 14.0 26.6 7.9 12.8 44.5 8.5 10.2 22.9 15.0 47.1 23.6 14.5 19.9 21.6 30.5 8.6 14.0 15.3 34.2 34.0 32.1 33.7 26.0 32.3 10.2 41.1 15.6 14.0 29.2 26.6 10.6 20.6 34.1 42.2 38.1 19.1 30.1 12.3 25.5 31.6 36.5 28.2 37.3 15.3 18.0 61.7 32.9 27.2 15.5 69.8 52.0 37.9 9.8 12.9 23.2 13.8 30.1 19.7 AGRN AGRIN ENSG00000188157 Agrin O00468 1 1020120-1056118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Differentiation "Developmental protein" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 94.5;Collecting duct cells: 156.3;Ductal cells: 91.2;Pancreatic endocrine cells: 87.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 205.3;EFO-21: 236.9;HaCaT: 210.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040090 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 20000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA040090: AB_10805603" "unprognostic (8.04e-2)" "unprognostic (8.25e-3)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.82e-3)" "unprognostic (1.32e-1)" "unprognostic (3.33e-2)" "unprognostic (9.49e-3)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" "unprognostic (1.31e-2)" 11.4 2.7 8.7 4.3 5.5 2.0 14.7 0.1 13.9 14.4 8.9 10.9 7.9 13.7 1.8 15.6 14.6 7.3 9.9 5.8 0.0 44.0 13.3 19.8 1.6 16.0 1.4 5.5 28.0 3.9 8.3 5.1 6.1 14.4 1.5 0.8 24.8 8.2 4.2 16.5 9.6 2.9 2.2 6.3 13.4 9.7 7.9 2.6 34.7 2.0 1.6 16.2 11.6 9.9 124.3 75.1 11.1 42.7 2.4 3.0 122.1 61.4 19.6 39.7 24.5 60.6 205.3 2.3 236.9 9.6 19.3 210.1 4.1 75.6 4.7 4.4 28.6 0.2 102.1 54.2 17.1 1.8 23.1 10.5 32.2 12.6 27.7 55.9 7.2 1.7 25.7 0.7 3.5 93.0 0.8 17.6 28.4 39.7 54.5 20.1 27.0 18.5 70.0 51.4 2.4 25.9 124.8 129.1 121.9 12.7 114.8 7.4 107.8 47.7 169.0 6.4 50.6 1.2 0.6 3.5 30.4 10.8 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 5.5 0.1 13.9 5.8 0.0 16.0 1.4 6.1 2.2 7.9 9.9 27.4 25.6 8.8 15.0 2.2 15.0 9.2 94.5 19.9 1.4 32.7 39.2 3.1 61.5 42.0 156.3 8.4 1.6 0.9 29.9 1.9 91.2 0.4 37.2 14.0 29.0 6.7 1.7 23.1 16.9 4.8 8.7 17.9 62.7 2.5 7.2 21.8 13.1 4.1 5.0 7.8 11.6 36.7 2.9 10.1 1.0 5.6 4.3 24.9 12.2 15.6 10.5 0.0 15.1 29.6 87.3 17.7 2.6 0.6 22.3 18.1 16.0 33.0 5.3 6.6 3.3 23.3 0.8 11.4 11.7 6.0 1.2 2.9 2.3 18.3 21.2 AGRP "Agrt, ART, ASIP2" ENSG00000159723 "Agouti related neuropeptide" O00253 16 67482571-67483547 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 122.5;epididymis: 37.1" "Group enriched" "Detected in some" 5 "Distal tubular cells: 3.9;Hofbauer cells: 8.8;Leydig cells: 3.1;Macrophages: 4.5;Peritubular cells: 2.6;Theca cells: 5.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in many" 60 "hypothalamus: 122.5" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "CACO-2: 1.2" "Region enriched" "Detected in single" 16 "hypothalamus: 16.0" "Region enhanced" "Detected in single" "hypothalamus: 2.0" HPA041017 Enhanced Supported "Secreted in brain" NA NA 255000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "HPA041017: AB_10795498" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (1.13e-1)" "unprognostic (4.16e-1)" "unprognostic (3.15e-1)" "unprognostic (1.10e-1)" "unprognostic (3.61e-1)" "unprognostic (3.34e-1)" "unprognostic (4.68e-1)" "unprognostic (1.29e-1)" "unprognostic (6.74e-2)" "unprognostic (3.17e-1)" "unprognostic (2.80e-1)" "unprognostic (1.72e-1)" "unprognostic (5.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-2)" 0.0 12.4 1.2 0.2 1.0 0.2 0.0 0.8 2.0 0.0 1.6 0.1 0.0 0.0 37.1 0.0 0.0 0.0 0.1 1.0 122.5 1.0 0.1 3.7 0.4 1.7 1.1 0.1 0.0 0.2 0.7 0.1 1.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.3 0.0 0.3 0.5 0.3 0.4 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.3 0.4 0.0 0.1 0.1 0.0 1.6 0.5 0.9 1.1 0.3 0.7 0.2 0.3 0.7 0.4 0.6 0.6 0.2 0.0 0.4 0.5 0.3 0.4 1.2 1.0 0.8 2.0 1.0 122.5 1.7 1.1 1.0 0.3 2.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.6 0.0 0.0 8.8 0.0 0.1 0.0 0.0 0.6 0.0 0.4 3.1 4.5 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 5.0 0.0 0.0 AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1603.7" "Group enriched" "Detected in many" 9 "Cholangiocytes: 985.1;Hepatocytes: 2244.9" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 646.2;THP-1: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" NA NA 5940000 65000000000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" 11.7 14.6 252.9 2.6 259.8 0.4 4.4 267.5 243.6 9.7 138.2 5.6 2.5 3.2 1.9 2.6 6.0 92.7 154.7 236.0 242.1 52.5 1603.7 5.1 1.0 352.4 314.4 3.5 7.9 6.0 25.8 0.7 304.9 16.3 3.6 26.4 4.9 2.2 43.6 2.0 9.7 5.8 340.5 1.3 4.9 4.1 273.5 1.7 13.2 25.8 0.1 7.0 4.5 322.4 0.2 0.4 0.2 0.2 15.6 0.0 0.9 0.6 0.2 0.0 0.0 80.6 0.1 0.3 0.7 0.2 0.7 0.7 0.0 0.0 0.0 11.4 0.2 0.2 0.3 646.2 1.9 1.0 0.5 26.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 5.5 0.7 0.0 0.2 0.6 0.6 0.1 0.2 0.3 2.4 0.1 0.1 0.3 0.9 0.6 0.4 0.1 5.5 0.1 0.0 243.6 0.1 0.4 1.3 0.4 1.2 3.5 47.0 0.4 0.4 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.9 259.8 267.5 243.6 236.0 242.1 352.4 314.4 304.9 340.5 273.5 322.4 0.8 0.0 1.7 140.0 11.3 0.6 1.1 0.0 0.0 4.7 0.8 0.3 60.0 985.1 0.6 3.7 35.5 0.1 0.0 0.0 25.4 169.8 62.2 0.3 0.4 5.5 0.0 50.8 0.3 10.0 0.2 27.2 0.5 0.1 0.0 0.0 39.3 2244.9 2.1 3.3 1.5 1.1 0.0 56.9 0.4 48.5 4.1 0.9 8.8 5.6 0.6 75.1 0.0 3.5 6.8 13.7 1.2 3.4 0.0 26.2 24.2 146.9 0.1 49.8 13.1 7.2 94.1 0.4 0.4 0.0 0.0 0.7 3.9 0.0 0.4 1.9 AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186613060-186621318 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4302 "liver: 5817.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 1242.5" "Cancer enriched" "Detected in some" 284 "liver cancer: 1231.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 78 "Hep G2: 2287.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 864000000000 110000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "CAB026209: , HPA001524: AB_1078851, HPA001525: AB_1078849" "unprognostic (6.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.03e-2)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (5.27e-2)" "unprognostic (8.64e-2)" "unprognostic (3.99e-7)" "unprognostic (5.21e-2)" "unprognostic (5.21e-2)" "unprognostic (1.04e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 1.3 5817.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.7 0.7 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.9 1.0 2287.3 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 3.5 0.0 0.0 1.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.2 0.0 0.1 3.9 0.2 4.3 0.2 0.1 0.9 0.0 32.0 0.6 0.6 2.4 0.1 0.0 0.1 0.0 0.0 28.2 1242.5 1.3 0.0 0.1 0.0 0.0 32.4 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.0 0.0 0.0 0.1 AIMP1 "EMAP-2, EMAPII, p43, SCYE1" ENSG00000164022 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 1" Q12904 4 106315544-106349456 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Inflammatory response, Protein biosynthesis" "Cytokine, RNA-binding, tRNA-binding" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017618, HPA018476" Supported Enhanced Cytosol "Secreted to blood" NA NA 6500000 35000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB017618: AB_2285445, HPA018476: AB_1848137" "unprognostic (1.17e-3)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.29e-3)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (7.13e-2)" "unprognostic (1.73e-1)" "unprognostic (2.27e-2)" 32.5 33.4 23.3 31.4 25.9 60.1 44.4 25.8 32.9 32.2 25.2 42.1 39.9 34.5 35.1 37.7 32.1 32.1 34.4 23.2 25.0 40.3 35.8 29.0 38.6 25.8 25.7 42.3 32.4 37.8 25.6 30.1 25.7 33.1 41.6 36.0 35.0 35.1 65.3 29.4 37.8 32.3 24.3 33.5 34.8 23.5 24.8 35.4 38.9 50.4 39.2 40.9 30.7 27.8 66.7 46.1 47.3 60.3 51.0 78.0 68.1 80.8 69.7 73.9 87.7 81.9 97.8 109.4 61.6 79.6 50.5 61.4 69.6 86.6 98.8 62.1 47.4 64.2 63.8 134.0 101.3 147.4 75.4 62.9 100.2 74.5 117.5 56.3 64.3 68.2 120.8 58.0 82.4 58.5 99.2 78.2 51.4 94.6 46.5 81.1 86.3 101.5 94.7 60.5 72.9 56.9 52.7 158.1 86.4 61.7 75.2 107.8 50.5 87.9 73.1 66.1 105.9 71.5 98.9 110.0 74.6 112.7 97.0 60.6 54.7 55.0 42.9 61.8 51.7 57.4 54.0 43.9 58.5 55.8 55.8 51.0 7.7 51.9 73.4 74.7 72.2 34.9 23.3 25.9 25.8 32.9 23.2 25.0 25.8 25.7 25.7 24.3 24.8 27.8 87.4 70.5 55.2 18.6 72.7 50.2 147.0 166.1 50.7 49.7 71.3 87.8 95.4 82.9 130.2 66.2 35.5 124.5 58.1 83.3 156.5 121.1 79.0 75.4 83.8 60.8 73.8 66.7 17.3 126.6 144.8 66.0 48.9 130.8 79.3 64.2 61.4 109.8 109.6 25.2 20.4 144.4 116.0 90.1 53.3 19.4 99.1 68.8 32.0 16.9 117.2 56.0 74.2 24.6 38.3 118.3 93.7 85.4 40.9 141.8 146.8 166.1 105.6 45.5 59.2 77.5 128.4 127.2 74.3 66.4 50.2 150.9 68.9 74.3 142.2 173.1 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 ALB ENSG00000163631 Albumin P02768 4 73397114-73421482 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "liver: 212494.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 65190.0" "Cancer enriched" "Detected in many" 384 "liver cancer: 14213.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 38 "Hep G2: 4500.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006262, HPA031024, HPA031025" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA 40000000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Endoplasmic reticulum" "CAB006262: AB_425297, HPA031024: AB_2673703, HPA031025: AB_2673704" "unprognostic (1.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.73e-1)" "unprognostic (2.60e-1)" "unprognostic (4.44e-1)" "unprognostic (2.46e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-2)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.84e-2)" "unprognostic (5.37e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.87e-4)" "unprognostic (7.23e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" 8.3 3.7 0.9 0.0 1.0 0.0 5.9 0.6 1.3 1.9 0.6 2.5 0.0 1.8 15.4 2.6 4.3 3.8 8.2 0.7 0.9 465.2 212494.0 6.7 1.3 0.7 0.8 2.5 1569.1 1.0 3.4 4.5 0.7 2.2 0.1 0.5 2.1 0.1 1.9 3.3 2.3 0.0 0.7 37.0 10.1 3.6 1.0 0.3 3.6 0.1 1.4 0.9 1.7 0.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 18.8 0.6 0.0 0.0 1.6 0.0 0.0 0.1 0.6 0.0 31.7 2.1 4500.0 0.0 117.1 3.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 17.0 0.2 0.0 0.1 2.0 0.0 4.0 0.0 0.1 2.1 95.1 0.0 0.0 3.2 0.0 0.0 52.3 0.0 0.0 0.0 0.0 0.0 13.5 0.0 1.4 0.1 0.1 7.0 0.6 32.9 0.1 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.7 0.7 1.0 0.8 0.1 0.0 0.0 1.0 187.5 0.0 0.0 0.0 0.0 0.0 43.4 18.9 0.1 13788.8 0.0 38.6 0.0 1.4 0.6 0.1 72.4 5.3 2.5 0.2 0.1 65.5 1.8 1133.8 0.2 273.8 11.1 0.5 4.6 0.0 0.0 0.1 1252.5 65190.0 8.5 0.0 0.2 0.0 0.0 1764.5 0.0 0.1 0.0 2.9 0.0 0.0 1.0 0.0 0.0 0.0 0.1 160.6 0.0 0.0 0.0 0.2 0.0 686.5 0.0 0.0 0.0 0.0 1.1 0.2 1.3 0.0 0.1 21.2 77.1 0.1 0.0 0.1 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALKAL1 "AUGB, FAM150A, UNQ9433" ENSG00000196711 "ALK and LTK ligand 1" Q6UXT8 8 52534037-52565430 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.4;thyroid gland: 2.4" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 5.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027368 Uncertain "Secreted - unknown location" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "HPA027368: AB_10602317" "unprognostic (1.18e-1)" "unprognostic (1.13e-4)" "unprognostic (9.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.52e-1)" "unprognostic (6.60e-2)" "unprognostic (1.70e-4)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (9.58e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 1.2 0.0 1.1 0.6 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.7 0.2 0.0 0.4 0.1 0.1 0.0 2.4 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.5 0.1 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 5.9 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALKAL2 "AUGA, FAM150B" ENSG00000189292 "ALK and LTK ligand 2" Q6UX46 2 279558-288851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 205.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 20.3;Ductal cells: 37.0;Endometrial ciliated cells: 24.0;Glandular and luminal cells: 50.3;Granulosa cells: 64.3;Proximal tubular cells: 28.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "AF22: 138.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 4.3;basal ganglia: 3.0;cerebral cortex: 2.5;hippocampal formation: 3.4;spinal cord: 2.3" "Secreted - unknown location" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.39e-3)" "unprognostic (1.44e-2)" "unprognostic (2.41e-2)" "unprognostic (2.03e-3)" "unprognostic (2.88e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.35e-1)" "unprognostic (9.29e-3)" "unprognostic (5.19e-2)" "unprognostic (3.68e-1)" 28.8 205.4 4.6 2.0 6.3 0.6 26.6 3.5 2.9 4.9 4.8 8.2 3.7 26.4 13.4 2.0 26.2 10.7 2.2 3.1 5.4 21.1 4.5 34.0 0.9 3.6 2.1 74.4 64.3 2.3 8.6 9.6 2.7 6.5 6.5 0.4 5.4 2.6 1.5 17.3 7.7 9.9 1.8 12.3 17.3 35.5 5.1 1.7 10.4 0.5 1.6 4.7 5.3 4.8 0.0 0.0 138.8 0.1 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.4 1.3 0.0 0.0 0.2 0.5 0.0 0.0 0.5 0.3 0.0 0.1 0.7 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.0 6.8 0.4 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.1 0.1 0.2 0.2 0.3 0.7 0.1 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.2 0.1 4.6 6.3 3.5 2.9 3.1 5.4 3.6 2.1 2.7 1.8 5.1 4.8 2.5 0.0 11.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 14.6 20.3 0.0 0.0 0.0 1.8 0.0 0.1 1.4 0.0 3.9 37.0 0.0 24.0 6.3 4.5 0.0 0.0 0.0 0.7 0.1 3.1 0.0 50.3 0.0 64.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.6 0.9 0.0 0.0 AMBN ENSG00000178522 Ameloblastin Q9NP70 4 70592256-70607288 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Microglial cells: 1.9" "Group enriched" "Detected in some" 7 "cervical cancer: 2.6;endometrial cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HEK 293: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036099 Uncertain Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA036099: " "unprognostic (3.22e-1)" 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 AMELX "AIH1, AMG" ENSG00000125363 "Amelogenin X-linked" Q99217 X 11293413-11300761 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "urothelial cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "unprognostic (1.76e-1)" "unprognostic (1.00e-1)" "unprognostic (2.00e-1)" 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.3 0.5 0.5 0.4 0.2 0.3 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AMELY AMGL ENSG00000099721 "Amelogenin Y-linked" Q99218 Y 6865918-6911774 "Predicted secreted proteins" Biomineralization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 AMH MIS ENSG00000104899 "Anti-Mullerian hormone" P03971 19 2249309-2252073 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Gonadal differentiation" "Growth factor" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 3.9;testis: 10.5" "Cell type enriched" "Detected in many" 61 "Granulosa cells: 1567.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 16.9;NTERA-2: 6.4;REH: 7.0;SH-SY5Y: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066973 Approved Vesicles,Aggresome "Secreted to blood" NA NA 1580000 280000 "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Aggresome" "HPA066973: AB_2732754" "unprognostic (8.10e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.21e-5)" "unprognostic (8.73e-3)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (8.03e-2)" "unprognostic (8.99e-2)" "unprognostic (2.55e-1)" "unprognostic (3.53e-1)" "unprognostic (5.95e-3)" "unprognostic (1.34e-2)" "unprognostic (8.73e-8)" "unprognostic (4.64e-2)" "unprognostic (4.14e-2)" "unprognostic (2.15e-1)" "unprognostic (2.76e-1)" 0.2 0.2 0.7 0.0 1.2 0.0 0.2 1.2 1.3 0.4 0.0 0.8 0.0 0.3 0.0 0.3 0.4 0.0 0.2 0.2 0.4 0.5 0.3 0.3 0.0 0.4 0.5 1.1 1.2 0.0 3.9 0.0 0.4 0.5 0.0 0.0 0.2 0.0 1.5 0.2 0.4 0.0 0.6 0.2 0.2 10.5 0.6 0.0 0.3 0.0 0.0 0.2 0.3 0.4 2.8 0.2 0.1 0.4 0.0 0.0 4.3 0.6 0.0 0.0 0.0 0.1 0.2 0.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.0 16.9 0.1 0.8 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.6 0.4 0.0 0.5 0.1 1.3 6.4 0.0 1.5 7.0 1.4 0.9 0.0 0.2 0.4 7.7 0.1 0.0 1.7 0.0 0.8 0.0 0.7 0.6 1.3 0.9 2.5 4.7 3.7 0.8 0.3 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 1.2 1.3 0.2 0.4 0.4 0.5 0.4 0.6 0.6 0.4 0.3 0.0 0.0 2.0 0.0 0.1 0.2 0.1 0.6 12.1 1.6 2.2 1.1 1.5 0.0 0.0 2.1 0.3 0.4 1.1 0.0 0.3 2.0 0.7 0.8 0.5 1.2 0.4 1.6 0.2 0.3 0.4 0.0 1.5 0.0 1567.5 0.7 0.3 0.1 8.4 11.5 1.0 0.0 0.0 0.0 9.2 1.5 2.3 0.0 1.9 0.1 6.3 0.0 1.0 2.2 0.0 0.0 0.4 0.1 0.1 0.9 0.2 0.1 2.3 0.0 9.2 25.6 8.1 0.6 0.7 0.1 0.0 0.4 0.0 0.8 0.2 AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 83.5;kidney: 39.8;liver: 37.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 672.6;Intestinal goblet cells: 283.9;Paneth cells: 724.4;Proximal enterocytes: 2014.8;Proximal tubular cells: 348.9;Undifferentiated cells: 272.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.2;CACO-2: 8.1;Hep G2: 9.9;U-698: 3.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA000817: AB_1078146" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.94e-3)" "unprognostic (7.39e-3)" "unprognostic (9.32e-2)" "unprognostic (1.88e-3)" "unprognostic (8.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (2.97e-2)" "unprognostic (7.57e-2)" "unprognostic (2.43e-2)" "prognostic favorable (9.62e-5)" "unprognostic (8.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" 1.4 0.0 0.1 1.1 0.2 0.1 0.5 0.1 0.2 1.5 0.0 33.0 43.5 0.1 0.0 5.6 1.1 1.9 0.0 0.2 0.1 39.8 37.8 1.7 0.1 0.3 0.1 0.1 0.7 0.0 0.5 0.0 0.3 0.7 3.0 0.0 1.2 0.0 0.0 2.3 83.5 0.1 0.1 0.5 8.0 0.8 0.1 0.1 0.8 0.0 0.0 0.3 2.5 0.3 0.3 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 8.1 0.1 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 9.9 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.1 0.7 1.2 0.0 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.7 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.1 0.3 0.1 0.1 0.3 0.2 9.6 0.5 0.7 18.0 13.4 23.4 1.3 12.0 3.3 13.1 2.0 1.5 140.2 6.1 20.2 0.0 2.7 4.7 672.6 33.2 1.8 4.8 8.2 1.1 0.6 19.2 0.8 0.1 0.7 4.1 0.9 61.7 10.5 4.5 1.9 0.4 52.6 0.6 1.7 0.1 283.9 6.1 1.6 2.3 6.3 0.6 3.1 7.2 0.0 0.1 0.2 1.0 0.0 0.1 11.1 724.4 0.7 4.5 28.1 2014.8 348.9 4.5 1.2 0.0 0.5 0.9 21.2 25.7 17.1 20.9 1.4 5.2 0.4 272.4 65.7 AMTN "RSTI689, UNQ689" ENSG00000187689 Amelotin Q6UX39 4 70518569-70532743 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 28.3;salivary gland: 6.8;stomach 1: 7.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 14.0;Ionocytes: 4.1" "Group enriched" "Detected in many" 11 "cervical cancer: 13.9;head and neck cancer: 38.3;lung cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 16.7;hTERT-RPE1: 23.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036136, HPA036137" Uncertain "Secreted in other tissues" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA036136: AB_2674963, HPA036137: AB_10673614" "unprognostic (1.72e-1)" "unprognostic (2.47e-1)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.86e-2)" "unprognostic (7.35e-2)" "unprognostic (2.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 6.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.3 0.0 0.1 0.3 0.0 0.0 28.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.7 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.5 23.7 0.1 0.0 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.5 14.0 0.0 0.0 0.1 0.3 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 AMY1A AMY1 ENSG00000237763 "Amylase alpha 1A" P04745 1 103655290-103664554 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 290 "salivary gland: 22089.3" "Cell type enriched" "Detected in some" 6 "Respiratory ciliated cells: 21.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004310, HPA045394, HPA045399, HPA046980" Enhanced "Secreted to digestive system" NA NA 70000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 49: Ciliated cells - Cilium organization" "CAB004310: AB_626668, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" 0.0 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 27.6 0.0 0.7 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.8 6.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 22089.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.5 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.2 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 AMY1B AMY1 ENSG00000174876 "Amylase alpha 1B" P04745 1 103687415-103696680 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "salivary gland: 4607.5" "Cell type enriched" "Detected in some" 5 "Respiratory ciliated cells: 19.1" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 70000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 49: Ciliated cells - Cilium organization" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (7.34e-2)" "unprognostic (2.59e-1)" "unprognostic (6.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 86.5 0.0 0.0 0.0 0.1 0.0 0.6 56.3 0.0 0.9 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.4 32.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4607.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.6 1.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.8 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 19.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 AMY1C AMY1 ENSG00000187733 "Amylase alpha 1C" P04745 1 103750406-103758690 "Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "pancreas: 125.9;salivary gland: 199.3" "Group enriched" "Detected in some" 7 "Alveolar cells type 2: 36.2;Respiratory ciliated cells: 51.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 70000000 "Cluster 25: Pancreas - Digestion" "Cluster 49: Ciliated cells - Cilium organization" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.1 0.0 0.0 13.3 0.0 0.0 0.0 0.3 125.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 199.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.8 0.0 4.6 10.8 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 AMY2A AMY2 ENSG00000243480 "Amylase alpha 2A" P04746 1 103616811-103625780 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1983 "pancreas: 148689.6" "Cell type enriched" "Detected in some" 114 "Exocrine glandular cells: 1016.0" "Cancer enriched" "Detected in single" 2010 "pancreatic cancer: 200.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045394, HPA045399, CAB045960, HPA046980" Enhanced "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "CAB045960: AB_2226891, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (3.27e-1)" "unprognostic (1.78e-3)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.13e-2)" 6.0 1.3 1.2 2.8 1.3 0.3 3.9 0.7 1.4 3.3 0.6 1.7 22.5 2.9 0.1 2.3 0.8 0.0 26.6 1.2 0.9 1.5 4.7 1.0 5.4 0.8 0.9 74.9 148689.6 0.1 1.5 8.3 0.8 2.1 0.0 0.6 30.0 0.0 1.5 1.4 10.7 0.0 0.7 1.7 2.2 1.2 0.9 0.0 1.1 0.0 0.0 0.5 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.7 1.4 1.2 0.9 0.8 0.9 0.8 0.7 0.9 1.0 0.1 0.0 0.0 2.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.1 0.0 0.0 0.2 0.0 0.0 1.3 1016.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.1 8.9 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.2 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 AMY2B AMY2 ENSG00000240038 "Amylase alpha 2B" P19961 1 103553815-103579534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 122 "pancreas: 31246.7" "Cell type enhanced" "Detected in many" "Astrocytes: 56.2;Excitatory neurons: 61.2;Exocrine glandular cells: 148.0;Inhibitory neurons: 48.4;Oligodendrocytes: 41.8" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.8;EFO-21: 10.3" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" NA NA 77000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" 35.4 24.8 29.5 11.2 34.8 13.4 34.9 39.9 38.6 40.8 19.7 33.0 16.5 22.7 20.2 13.1 50.3 14.1 40.9 27.9 29.5 59.4 39.0 30.2 20.0 27.7 29.1 40.0 31246.7 14.9 36.8 6.9 27.1 35.3 11.9 69.8 256.2 14.6 63.7 42.6 31.7 9.8 26.3 34.8 18.1 5.2 30.6 12.6 63.5 25.2 13.8 29.3 25.8 30.0 0.0 0.5 1.1 0.0 5.6 9.8 1.1 0.8 0.8 0.6 1.5 0.0 0.2 1.0 10.3 0.3 0.0 1.2 0.1 1.3 1.4 1.3 1.6 1.9 4.5 0.8 0.8 2.5 2.6 6.7 6.7 0.8 1.2 1.8 0.2 3.0 0.0 3.2 0.9 0.0 1.9 0.5 0.1 0.1 1.4 0.5 0.0 4.7 5.7 2.0 2.8 0.6 2.4 1.1 0.8 1.8 0.1 1.4 0.8 0.3 0.9 0.5 0.7 3.5 0.1 0.3 1.9 1.8 0.2 0.0 5.0 1.0 0.4 2.5 0.3 1.0 0.1 0.2 1.6 0.9 0.6 0.2 1.2 0.1 2.2 0.5 0.2 1.2 29.5 34.8 39.9 38.6 27.9 29.5 27.7 29.1 27.1 26.3 30.6 30.0 2.8 12.8 20.1 56.2 3.2 4.7 4.2 1.4 0.6 11.7 2.9 2.7 7.2 2.8 11.2 1.8 33.3 0.4 2.4 3.6 0.0 1.3 7.3 1.1 0.6 2.7 4.9 1.3 61.2 148.0 0.4 3.2 2.0 0.7 3.8 0.5 2.2 6.5 1.6 10.1 48.4 2.5 0.0 9.4 3.5 2.7 2.5 3.4 5.4 11.2 4.0 3.1 2.1 22.1 41.8 1.3 2.7 1.9 1.4 1.5 4.3 0.8 14.6 15.4 0.0 1.0 2.5 1.5 0.9 0.4 3.0 0.3 1.7 0.4 2.2 1.6 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANGPT1 "Ang1, KIAA0003" ENSG00000154188 "Angiopoietin 1" Q15389 8 107249482-107498055 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 33.5" "Group enriched" "Detected in many" 4 "Astrocytes: 60.4;Fibroblasts: 20.4;Inhibitory neurons: 37.6;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.8" "Cell line enhanced" "Detected in many" "ASC diff: 87.9;HEL: 53.1;HSkMC: 145.5;U-138 MG: 70.5;WM-115: 47.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017815, HPA018793, HPA018816" Approved "Secreted to blood" NA NA 32000000 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB017815: , HPA018793: AB_1844820, HPA018816: AB_1844821" "unprognostic (7.71e-2)" "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (4.11e-3)" "unprognostic (7.36e-2)" "unprognostic (3.80e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (1.07e-2)" "unprognostic (5.54e-2)" "unprognostic (2.62e-1)" "unprognostic (1.44e-1)" "prognostic favorable (4.40e-4)" "unprognostic (4.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" 25.1 5.6 3.2 2.6 4.5 0.7 4.6 4.5 2.2 5.8 2.5 3.4 2.3 3.5 4.8 3.5 3.0 13.2 4.8 4.5 6.1 11.1 2.1 21.7 1.4 8.0 3.5 9.5 1.6 1.2 5.8 20.5 4.8 17.7 3.3 0.6 12.0 33.5 23.4 1.2 2.6 3.3 4.8 11.0 4.0 2.3 2.1 2.1 3.5 7.0 1.0 3.9 3.7 11.9 0.0 2.4 9.3 5.3 87.9 30.2 6.6 30.0 25.8 8.1 11.9 6.2 0.1 0.0 0.1 16.0 0.0 0.0 4.2 0.1 10.5 0.0 1.4 53.1 0.6 0.0 24.5 0.7 0.0 145.5 0.0 4.9 0.6 7.5 0.6 0.0 28.2 5.1 10.9 0.0 1.1 7.9 9.6 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.1 4.2 1.1 0.6 0.0 11.6 2.2 0.0 0.3 70.5 0.9 2.5 0.7 0.2 3.2 0.0 9.7 1.1 47.5 0.1 0.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.8 0.1 0.3 0.0 0.0 0.6 3.2 4.5 4.5 2.2 4.5 6.1 8.0 3.5 4.8 4.8 2.1 11.9 9.0 0.0 2.3 60.4 0.0 0.6 10.1 0.4 5.2 0.9 0.5 2.8 3.3 0.0 2.2 7.3 0.0 5.2 0.0 0.0 1.9 0.3 8.1 0.7 9.1 5.6 0.0 10.1 6.5 0.0 7.6 20.4 1.5 1.9 0.0 0.0 3.3 0.1 0.5 0.0 37.6 0.0 2.0 0.3 1.0 2.4 2.5 2.9 0.0 6.5 1.5 0.5 0.0 3.0 0.6 0.0 0.0 3.8 1.1 1.2 0.0 2.8 0.8 0.0 6.6 3.5 48.6 1.6 5.4 4.0 0.1 2.7 0.8 1.7 0.1 1.2 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANGPT4 ENSG00000101280 "Angiopoietin 4" Q9Y264 20 869900-916334 "Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 7.2;breast: 6.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 52.9;Late spermatids: 17.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "ASC diff: 33.7;BEWO: 48.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013260, CAB013305" Uncertain "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB013260: , CAB013305: " "unprognostic (1.77e-1)" "unprognostic (3.25e-1)" "unprognostic (4.30e-2)" "unprognostic (1.04e-3)" "unprognostic (6.37e-2)" "unprognostic (3.41e-1)" "unprognostic (5.82e-4)" "unprognostic (1.25e-1)" "unprognostic (7.10e-2)" "unprognostic (3.66e-4)" "unprognostic (9.01e-2)" "unprognostic (1.71e-1)" "unprognostic (5.25e-2)" "unprognostic (1.23e-2)" "unprognostic (1.55e-1)" "unprognostic (2.95e-4)" "unprognostic (9.14e-2)" 7.2 0.3 0.3 0.1 0.3 0.0 6.6 0.2 0.3 3.8 0.1 0.3 0.1 3.3 2.1 0.2 3.3 0.3 0.2 0.2 0.4 0.2 0.2 1.2 0.1 0.3 0.3 3.9 0.1 0.1 0.0 0.0 0.4 0.5 0.1 0.1 0.3 0.4 0.0 1.4 0.3 1.1 0.2 0.0 0.3 0.6 0.4 0.2 1.7 0.6 0.0 1.0 2.2 0.3 0.2 0.0 0.0 0.0 33.7 0.0 48.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.3 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.3 0.3 0.0 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 52.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.3 17.0 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.9 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 133.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 81.7;Leydig cells: 425.9;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "ASC diff: 149.9;ASC TERT1: 60.1;HHSteC: 64.9;HSkMC: 147.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" NA NA 380000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" 56.6 45.1 2.0 10.5 2.7 0.9 26.9 2.3 2.7 21.3 1.5 56.7 9.6 69.2 14.0 33.8 59.0 27.9 22.8 2.9 1.9 17.5 23.9 12.6 3.5 2.1 1.5 68.2 21.9 1.1 2.1 133.8 1.4 12.3 27.5 9.6 36.3 9.5 30.3 9.0 26.7 65.5 2.2 10.9 21.6 15.6 1.7 8.6 41.1 57.3 6.9 23.9 17.1 2.3 0.2 0.0 4.0 0.0 149.9 60.1 0.0 0.1 0.0 0.4 0.8 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 64.9 0.0 0.1 147.5 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 2.7 2.3 2.7 2.9 1.9 2.1 1.5 1.4 2.2 1.7 2.3 16.5 0.0 0.0 9.4 1.3 3.7 0.0 0.0 1.2 2.3 0.8 0.5 3.7 41.5 0.0 1.8 6.2 0.6 0.1 0.0 1.9 2.4 1.4 3.3 40.3 4.1 0.0 0.0 14.8 0.4 0.4 81.7 1.1 5.5 0.0 1.6 8.9 1.0 1.4 0.0 14.9 0.0 0.0 0.0 4.6 10.6 425.9 0.8 3.6 8.4 0.0 31.6 0.0 21.6 0.7 0.0 5.0 212.1 0.4 0.1 0.1 0.1 0.7 10.9 39.5 10.0 51.8 0.8 0.6 0.2 3.7 1.4 0.5 2.7 0.0 0.1 ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.4;Endothelial cells: 34.6;Fibroblasts: 99.7;Oligodendrocyte precursor cells: 35.2;Skeletal myocytes: 39.3;Smooth muscle cells: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 140.4;ASC TERT1: 94.9;BJ hTERT+: 205.9;HSkMC: 98.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 2510000 2200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" 109.5 11.5 6.1 33.5 12.9 0.2 71.2 15.1 8.6 67.7 12.4 76.5 15.1 72.9 13.7 21.7 31.4 67.0 69.2 6.9 9.4 13.4 14.8 22.5 8.1 12.0 12.4 44.2 5.5 4.1 3.4 21.4 11.7 24.7 17.9 0.9 18.0 27.1 57.6 29.2 27.8 63.4 9.9 49.2 28.9 4.4 12.6 4.7 15.7 36.6 8.9 59.4 49.1 15.4 0.0 0.0 17.4 0.0 140.4 94.9 9.4 8.1 205.9 9.2 8.5 0.0 0.0 0.0 7.0 21.4 1.8 0.1 1.7 0.0 4.8 0.1 0.0 0.0 0.1 0.5 30.3 0.1 0.0 98.2 0.0 20.0 0.0 28.7 27.6 2.3 0.0 0.1 6.3 0.0 0.2 4.3 18.4 0.0 1.0 16.5 27.3 1.6 2.2 0.0 9.3 10.1 0.0 0.0 0.0 3.3 0.0 0.0 8.8 35.5 4.5 50.4 0.0 0.0 0.1 0.0 37.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 12.9 15.1 8.6 6.9 9.4 12.0 12.4 11.7 9.9 12.6 15.4 47.4 9.6 2.4 1.0 0.1 14.3 7.0 0.2 3.4 14.4 0.6 6.6 16.6 0.0 0.1 0.0 2.1 1.0 0.5 0.1 0.0 0.2 1.6 1.4 20.2 34.6 0.0 0.0 0.6 0.0 0.8 99.7 1.1 1.0 0.0 2.9 5.0 0.0 1.4 0.0 1.5 0.0 0.0 0.0 17.4 1.5 20.8 0.8 7.2 1.9 0.0 1.9 0.0 35.2 19.2 1.2 0.0 6.4 0.0 1.7 0.0 2.4 1.6 0.8 0.0 39.3 43.5 1.0 0.0 1.4 11.1 2.6 1.7 1.1 0.0 0.6 ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 675.7" "Group enriched" "Detected in some" 12 "Hepatocytes: 567.6;Proximal tubular cells: 272.5" "Cancer enriched" "Detected in some" 39 "liver cancer: 94.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038097 Approved "Secreted to blood" NA NA 225000000 120000000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038097: AB_10675628" "unprognostic (2.29e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (4.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-3)" "unprognostic (6.85e-3)" "unprognostic (2.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.09e-2)" "unprognostic (5.38e-2)" "unprognostic (7.62e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 53.0 675.7 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 11.5 0.0 5.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.1 0.1 0.7 0.0 16.0 0.1 0.2 0.1 0.0 2.6 0.3 0.0 0.0 9.7 567.6 0.1 0.0 0.1 0.0 0.0 16.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 ANGPTL4 "ARP4, FIAF, HFARP, NL2, PGAR, pp1158" ENSG00000167772 "Angiopoietin like 4" Q9BY76 19 8363289-8374370 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 195.8;breast: 165.0;liver: 183.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 318.9;Hepatocytes: 148.4;Pancreatic endocrine cells: 230.4;Proximal enterocytes: 146.3;Skeletal myocytes: 198.3" "Cancer enriched" "Detected in all" 4 "renal cancer: 212.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "ASC diff: 54.6;HBEC3-KT: 226.5;LHCN-M2: 60.9;TIME: 114.6;U-138 MG: 65.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA007879, CAB033770" Approved Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 7750000 3100000 "Cluster 41: Basophils - Cellular respiration" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "CAB033770: AB_2057427, HPA007879: AB_1078158" "unprognostic (1.26e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (7.53e-4)" "unprognostic (1.88e-2)" "unprognostic (7.68e-3)" "unprognostic (3.58e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (3.18e-1)" "unprognostic (3.90e-3)" "unprognostic (9.69e-3)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.00e-2)" 195.8 23.0 25.2 15.4 31.8 1.4 165.0 26.2 32.6 18.8 14.0 25.6 11.5 6.8 0.1 41.2 7.9 9.4 45.4 27.7 27.0 51.9 183.7 46.6 2.0 30.1 37.6 9.1 70.8 1.0 16.1 18.3 27.2 30.4 0.9 3.2 19.1 2.6 24.8 30.2 28.0 6.0 27.3 13.1 21.7 6.7 33.8 0.7 34.1 6.2 2.8 26.6 32.1 33.7 0.1 2.2 1.2 3.3 54.6 12.0 0.7 4.4 0.5 0.7 0.2 0.0 20.9 0.2 30.6 8.8 4.5 3.0 0.0 226.5 0.4 1.9 0.4 0.3 0.9 0.9 1.2 0.1 0.2 5.6 1.0 34.0 0.7 6.2 17.4 0.6 1.1 0.5 60.9 1.8 0.2 2.1 0.3 0.0 1.8 1.3 0.1 1.0 11.1 4.0 0.2 0.5 26.2 2.7 4.3 1.5 6.8 0.4 114.6 65.1 0.3 33.3 0.0 0.3 0.1 0.2 44.9 0.0 12.4 3.3 0.1 0.4 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.9 0.3 0.0 0.1 0.2 0.1 25.2 31.8 26.2 32.6 27.7 27.0 30.1 37.6 27.2 27.3 33.8 33.7 53.5 38.5 5.8 128.0 1.2 14.0 39.8 318.9 17.1 0.2 71.8 49.0 5.3 1.5 85.7 14.7 0.0 7.4 2.5 17.1 0.0 107.1 0.7 4.2 6.9 28.9 0.0 0.0 0.4 18.0 111.2 89.1 46.9 13.8 2.5 1.5 17.9 148.4 8.3 0.0 0.6 14.2 16.2 1.6 10.3 2.2 88.0 5.0 8.8 2.8 2.0 2.7 0.0 1.0 4.5 230.4 8.4 131.7 1.0 38.3 146.3 4.5 19.0 0.1 32.9 198.3 121.5 0.0 3.1 21.8 11.5 40.1 2.3 20.7 6.7 77.7 ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "ovary: 22.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 19.4;Langerhans cells: 11.3;Leydig cells: 27.7;Melanocytes: 7.2;Peritubular cells: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 2.7" "Region enhanced" "Detected in some" "spinal cord: 3.3" HPA038516 Uncertain "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038516: AB_10672749" "unprognostic (8.28e-3)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-1)" "unprognostic (4.88e-2)" "unprognostic (6.74e-4)" "unprognostic (1.96e-1)" "unprognostic (1.53e-8)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-3)" 4.3 0.2 0.1 0.0 0.2 0.0 5.5 0.2 0.4 0.2 0.4 0.3 0.1 0.0 4.4 0.2 0.3 0.2 2.7 0.2 0.2 0.0 0.0 0.9 0.1 0.2 0.1 22.4 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.4 0.2 0.4 2.4 0.2 0.0 0.2 0.0 0.1 1.6 0.1 0.0 0.7 1.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 2.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 2.1 0.9 0.6 0.8 0.0 0.0 2.7 0.0 0.1 19.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 11.3 0.8 27.7 0.1 7.2 4.7 0.0 0.2 0.0 1.0 0.2 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.2 1.0 0.2 0.2 0.0 5.5 0.1 0.5 5.7 0.0 0.0 ANGPTL6 "AGF, ARP5" ENSG00000130812 "Angiopoietin like 6" Q8NI99 19 10092338-10102796 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 30.2" "Cell type enhanced" "Detected in some" "B-cells: 4.1;Hepatic stellate cells: 5.7;Hepatocytes: 8.2;Smooth muscle cells: 15.8;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HMC-1: 58.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 450000 23000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.28e-1)" "unprognostic (2.18e-6)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-1)" "unprognostic (1.02e-2)" "unprognostic (8.77e-2)" "unprognostic (5.25e-2)" "unprognostic (1.00e-1)" "unprognostic (2.99e-2)" "unprognostic (1.23e-2)" "unprognostic (1.85e-1)" "unprognostic (2.26e-10)" "unprognostic (8.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" 0.3 0.3 0.8 2.1 0.7 2.8 0.3 0.8 1.1 0.2 0.4 0.6 0.7 0.1 0.2 0.3 0.7 0.4 0.2 0.7 0.8 0.5 30.2 0.5 3.3 1.7 1.1 0.3 1.1 0.1 0.4 2.2 1.3 0.2 0.4 0.1 0.2 0.0 0.0 0.3 3.5 0.2 1.2 3.4 1.6 1.6 1.0 0.8 0.3 0.0 3.3 0.5 0.2 1.7 0.3 0.0 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.2 0.0 0.1 7.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 2.0 0.2 0.2 0.0 0.5 58.9 0.0 0.2 0.1 0.1 0.3 0.0 0.6 0.4 0.3 0.0 0.0 1.3 4.7 0.2 0.4 1.1 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.3 0.0 0.5 0.0 0.0 5.0 0.0 0.1 0.1 0.0 0.0 5.1 1.4 2.9 0.2 0.7 0.7 0.0 0.3 0.0 0.6 0.4 0.4 0.7 0.4 0.4 0.1 0.9 0.2 0.4 0.0 0.4 0.2 0.1 0.5 0.2 0.8 0.7 0.8 1.1 0.7 0.8 1.7 1.1 1.3 1.2 1.0 1.7 0.3 0.0 0.0 0.0 4.1 0.3 0.1 0.4 0.0 0.1 0.4 0.3 0.4 2.8 0.3 0.0 0.0 0.2 1.7 0.1 1.9 0.3 0.3 0.0 0.3 0.2 0.0 0.4 0.9 0.0 0.2 2.5 0.5 0.1 0.0 0.1 5.7 8.2 2.3 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 2.1 0.0 0.2 0.5 0.2 0.2 0.0 0.1 15.8 0.5 6.3 0.0 0.0 0.3 1.0 0.9 0.1 0.1 ANGPTL7 "AngX, CDT6" ENSG00000171819 "Angiopoietin like 7" O43827 1 11189355-11195981 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Cardiomyocytes: 4.1;Enteroendocrine cells: 1.8;Fibroblasts: 6.9;Melanocytes: 3.6;Microglial cells: 1.9" "Cancer enriched" "Detected in some" 14 "melanoma: 18.4" "Region enhanced" "Detected in some" "thalamus: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 65 "SCLC-21H: 41.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 13 "spinal cord: 62.2" "Secreted in other tissues" NA NA 1100000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-2)" "unprognostic (6.95e-2)" "unprognostic (1.22e-1)" "unprognostic (2.67e-3)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.89e-2)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (1.58e-2)" "unprognostic (3.41e-3)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "unprognostic (2.49e-2)" 15.9 2.2 0.3 1.3 0.2 0.0 5.3 1.9 1.0 4.8 0.2 9.2 0.8 0.5 2.1 2.2 2.2 3.8 7.6 0.1 0.4 2.7 0.1 1.3 0.0 0.4 0.5 0.4 0.4 0.0 4.2 0.6 0.3 4.2 1.5 0.2 2.3 6.6 7.8 6.2 1.8 1.9 0.0 0.3 2.3 0.2 4.3 0.3 0.7 5.7 0.2 4.2 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.9 1.0 0.1 0.4 0.4 0.5 0.3 0.0 4.3 0.4 0.1 3.2 0.0 0.3 0.0 0.1 0.1 0.0 1.2 0.1 0.2 0.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.8 0.0 0.3 0.0 0.0 6.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ANGPTL8 "C19orf80, RIFL, TD26" ENSG00000130173 "Angiopoietin like 8" Q6UXH0 19 11237450-11241943 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Hormone "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 409.8" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 151.2" "Cancer enriched" "Detected in some" 37 "liver cancer: 84.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "Hep G2: 37.0;MCF7: 21.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA042131 Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 836000 350000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" Nucleoplasm "HPA042131: AB_10794413" "unprognostic (2.37e-2)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-2)" "unprognostic (1.17e-1)" "unprognostic (1.00e-1)" "unprognostic (3.73e-1)" "unprognostic (2.80e-1)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" "unprognostic (9.67e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (4.57e-1)" "unprognostic (1.75e-2)" 35.7 0.8 1.1 0.2 1.0 0.1 22.5 0.1 1.7 1.2 0.0 1.4 0.4 0.9 1.6 0.3 0.8 0.4 1.8 0.9 0.6 4.0 409.8 0.4 0.1 0.7 0.6 1.1 0.9 0.0 0.3 0.1 0.5 0.8 0.0 0.1 1.3 0.1 0.8 0.9 1.2 0.1 0.3 0.4 0.7 0.5 1.1 0.0 1.0 0.0 0.0 1.1 1.0 0.9 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 1.3 37.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 21.2 0.0 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.0 0.3 0.0 0.3 0.4 0.9 0.0 0.4 0.6 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.1 1.7 0.9 0.6 0.7 0.6 0.5 0.3 1.1 0.9 0.6 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.4 0.2 0.8 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.3 0.2 0.0 2.7 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 4.6 151.2 0.1 0.0 0.0 0.0 0.0 4.4 0.0 1.9 0.9 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.2 0.0 0.1 ANKDD1A FLJ25870 ENSG00000166839 "Ankyrin repeat and death domain containing 1A" Q495B1 15 64911902-64958691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 209.6;Leydig cells: 61.8;Peritubular cells: 78.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 24.1;RT4: 17.7;U-266/84: 25.4" "Low region specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 13.8" HPA040757 Approved Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA040757: AB_10960566" "unprognostic (3.72e-4)" "unprognostic (1.86e-1)" "unprognostic (6.07e-3)" "unprognostic (3.25e-2)" "unprognostic (4.78e-1)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-3)" "unprognostic (5.11e-3)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (1.60e-1)" "unprognostic (3.15e-7)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (8.04e-3)" "unprognostic (1.64e-2)" 3.6 9.0 5.1 2.6 4.5 2.7 1.5 2.0 5.4 2.3 0.1 1.3 1.2 2.2 1.9 3.6 4.0 2.9 2.2 3.8 2.5 0.8 0.4 2.6 4.8 4.7 2.7 3.8 4.4 4.4 1.2 1.6 2.2 2.3 0.4 2.8 2.4 2.1 1.2 3.3 1.8 1.6 2.1 10.7 1.7 3.6 3.5 0.8 2.6 0.1 1.3 3.0 2.0 2.5 1.2 3.7 1.6 1.6 2.7 2.1 6.9 1.6 4.4 1.7 2.5 2.1 1.7 1.6 1.9 3.8 1.4 1.3 3.7 0.3 1.4 0.7 1.1 1.5 4.6 1.5 2.0 1.2 2.5 1.6 0.5 1.1 0.6 0.9 1.2 1.7 0.3 24.1 0.5 3.5 0.6 2.6 2.2 0.6 1.7 0.8 1.0 12.1 0.2 17.7 3.2 4.5 1.0 1.2 1.8 1.5 1.2 1.5 1.8 3.2 3.3 2.8 1.6 6.4 25.4 1.2 3.6 3.0 1.0 0.5 0.4 0.0 1.0 0.9 0.3 0.4 0.5 1.4 0.7 0.3 0.3 0.4 0.7 3.1 0.9 0.0 2.1 0.4 5.1 4.5 2.0 5.4 3.8 2.5 4.7 2.7 2.2 2.1 3.5 2.5 8.0 0.0 1.3 209.6 1.5 5.6 4.2 1.1 4.0 11.2 0.7 1.0 1.4 1.5 1.3 0.0 12.5 3.1 3.8 0.1 0.0 0.9 1.1 1.7 9.6 12.7 1.2 0.0 37.7 2.3 5.6 6.5 0.0 3.6 5.7 1.1 5.3 0.0 5.4 3.3 24.6 0.0 2.0 6.0 25.4 4.1 61.8 7.1 10.6 19.7 1.1 28.9 5.2 30.2 10.7 2.8 0.1 78.6 6.2 2.7 0.0 0.3 0.2 8.2 13.1 11.8 7.1 2.6 1.3 0.8 3.7 2.2 3.0 3.3 0.1 5.2 ANOS1 "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSG00000011201 "Anosmin 1" P23352 X 8528874-8732137 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.1" "Cell type enriched" "Detected in many" 11 "Alveolar cells type 1: 240.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 40.4;NTERA-2: 37.0;U-2 OS: 17.6" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.93e-1)" "unprognostic (5.33e-2)" "unprognostic (9.54e-2)" "unprognostic (4.16e-3)" "unprognostic (7.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.17e-3)" "unprognostic (4.53e-2)" "unprognostic (6.43e-2)" "unprognostic (2.09e-2)" "unprognostic (6.24e-2)" "unprognostic (1.71e-2)" "unprognostic (9.38e-3)" "unprognostic (6.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.56e-2)" 6.6 4.0 7.6 1.1 10.5 0.3 3.7 6.0 7.3 4.4 0.9 0.6 0.3 0.5 3.1 1.3 1.1 1.7 5.0 8.3 12.2 0.8 0.8 43.1 1.9 13.8 11.5 0.3 0.4 15.1 0.5 1.2 14.8 4.1 1.0 19.6 2.4 4.4 10.5 3.1 0.6 0.7 18.6 0.8 0.8 3.9 12.6 4.0 9.3 6.8 0.9 1.2 1.2 17.9 0.1 0.0 1.9 0.0 0.0 0.0 2.2 0.8 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.7 4.0 0.2 5.5 0.5 5.6 0.0 0.0 0.0 1.5 0.1 3.1 0.3 0.1 40.4 0.0 0.1 0.0 0.0 0.5 0.4 0.3 0.0 37.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 2.1 0.1 1.9 0.5 0.0 4.8 0.0 1.0 0.0 0.0 17.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 10.5 6.0 7.3 8.3 12.2 13.8 11.5 14.8 18.6 12.6 17.9 1.7 240.4 12.6 0.0 0.0 0.0 4.7 0.0 13.1 20.5 6.2 3.4 6.2 0.0 19.8 0.0 4.2 0.1 0.0 0.0 0.0 0.9 0.2 0.4 1.5 1.6 0.0 0.0 0.0 0.0 0.3 10.9 0.0 0.1 1.3 2.2 6.1 0.0 5.1 0.0 0.0 0.0 0.0 2.9 0.0 0.3 0.6 3.0 0.0 0.0 0.2 17.8 0.0 0.0 0.0 1.5 0.1 1.2 0.0 3.1 0.0 0.2 3.6 1.6 0.0 8.7 3.3 0.6 1.6 1.5 0.0 0.1 0.3 0.8 0.4 1.1 ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7527.7" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 3632.9;Syncytiotrophoblasts: 7071.8;Urothelial cells: 4808.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2816.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA Yes 3000000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" 719.8 60.3 27.5 268.3 35.1 2132.2 442.6 24.8 44.4 952.0 32.8 152.7 64.1 116.2 58.6 7527.7 264.6 329.4 145.3 28.4 53.4 67.9 54.7 470.4 67.9 55.5 46.4 109.4 61.8 28.2 98.1 559.4 36.5 165.3 103.2 6.5 1547.5 154.9 47.6 213.8 88.7 261.5 40.4 79.6 90.2 17.9 45.9 109.9 206.8 89.1 1485.5 386.3 1536.1 43.2 960.2 1485.7 65.8 68.4 905.8 855.6 4.2 1614.6 1008.5 656.3 441.9 43.5 841.0 2.2 520.1 1426.5 1441.9 1147.7 142.6 984.1 516.8 541.6 10.3 73.2 398.5 1.4 719.4 160.9 34.7 495.7 800.6 664.7 1294.6 604.0 947.8 85.4 309.3 39.5 822.6 4.3 287.0 87.7 82.6 379.7 597.6 0.9 369.1 3.2 1495.9 200.4 1.0 0.7 556.6 14.7 377.9 862.7 3.5 24.3 1176.2 761.8 478.9 1058.2 845.1 6.8 2.0 3.6 1757.9 147.8 1171.2 2816.9 1237.6 2227.6 744.1 328.7 757.0 13.7 662.7 664.5 1513.3 3.3 190.7 348.5 128.4 443.6 324.0 53.2 134.5 2021.5 27.5 35.1 24.8 44.4 28.4 53.4 55.5 46.4 36.5 40.4 45.9 43.2 447.4 583.3 415.2 1.6 39.0 846.7 2486.8 2417.6 1748.3 0.1 225.0 417.1 22.5 58.6 2214.7 62.5 0.0 1543.4 602.1 32.2 0.0 167.4 8.2 2037.4 241.6 362.2 5.3 81.2 3.7 23.1 1747.7 732.0 86.6 1993.5 2550.6 0.1 136.7 6.5 593.8 0.0 0.1 20.8 1330.6 545.0 1190.3 7.3 222.4 901.7 307.7 29.0 575.0 0.2 319.3 0.5 0.6 733.2 5.5 9.4 140.4 1552.2 0.1 5.7 1996.9 0.0 65.7 728.2 413.3 2.3 4.0 3632.9 597.7 7071.8 1348.3 3.0 12.6 4808.1 ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2185.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5755.6;Pancreatic endocrine cells: 5217.8;Prostatic glandular cells: 4575.5;Urothelial cells: 4326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4429.7;classical monocyte: 2762.3;intermediate monocyte: 2401.9;myeloid DC: 4018.8;non-classical monocyte: 2686.5;T-reg: 1681.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 174.7" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 19000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" 975.6 370.5 49.0 461.9 50.5 151.7 708.5 49.6 96.9 806.3 95.6 631.2 502.0 296.2 267.2 2185.3 388.4 453.9 393.0 47.6 79.4 358.3 185.5 878.3 200.7 90.0 83.6 187.0 324.3 344.0 163.9 650.4 84.9 399.3 606.1 30.2 933.4 386.4 304.8 1140.8 487.5 425.4 73.3 301.6 379.0 116.1 120.9 188.7 351.2 205.8 541.1 842.2 1256.7 80.1 4183.3 4421.4 223.6 105.5 2962.4 4744.2 971.0 4703.6 2968.4 2868.4 2534.9 2083.5 1903.6 10.0 3907.2 5983.6 2185.1 4304.9 992.9 8695.5 3113.5 846.8 103.9 78.2 1918.7 882.7 1782.0 4.5 59.9 2324.4 2278.6 2013.2 4335.0 3477.2 5455.0 58.4 320.9 447.9 6271.8 468.4 18.5 239.1 508.2 3444.1 3283.5 48.9 1198.8 226.6 5172.4 2410.7 295.1 171.9 1774.5 424.8 1942.8 2305.1 922.7 173.6 6336.8 2534.1 3406.8 8668.0 4807.4 172.6 616.3 83.8 2449.2 47.9 5206.0 4429.7 2762.3 355.0 603.8 2401.9 668.5 657.9 686.4 701.7 4018.8 412.1 77.0 313.9 73.6 287.1 2686.5 609.4 1681.4 3754.4 49.0 50.5 49.6 96.9 47.6 79.4 90.0 83.6 84.9 73.3 120.9 80.1 673.9 2141.0 414.8 0.3 101.3 2512.2 3396.9 5755.6 246.4 2.5 395.9 337.4 28.2 773.5 3086.6 560.9 0.0 1874.5 135.9 933.6 13.7 3941.4 93.0 855.9 457.1 772.0 103.4 38.7 0.2 2411.4 2714.4 1076.7 328.7 1376.3 105.7 97.5 474.0 64.2 1537.2 0.0 1.3 689.0 1668.2 429.6 1992.1 126.6 771.1 715.1 1417.6 15.9 1284.0 19.4 138.0 1.5 0.1 5217.8 920.9 638.7 144.5 4575.5 845.8 51.8 2446.8 8.1 184.1 437.7 831.1 13.0 29.3 789.7 2325.1 1150.1 224.1 8.6 749.9 4326.1 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 AOC1 "ABP, ABP1, DAO" ENSG00000002726 "Amine oxidase copper containing 1" P19801 7 150824627-150861504 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 227.2;kidney: 136.5;placenta: 496.7" "Cell type enhanced" "Detected in many" "Collecting duct cells: 272.2;Distal enterocytes: 517.5;Paneth cells: 532.1;Proximal enterocytes: 957.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 12 "eosinophil: 31.2" "Lineage enriched" "Detected in many" 22 "granulocytes: 31.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.5;HaCaT: 6.2;NB-4: 6.4;RPMI-8226: 7.7;THP-1: 27.1" "Low region specificity" "Detected in many" "HPA031032, HPA031033" Approved "Secreted in other tissues" NA NA 2500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA031032: AB_10670150, HPA031033: AB_10669670" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-3)" "unprognostic (9.07e-3)" "unprognostic (6.42e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.71e-4)" "unprognostic (5.32e-3)" "unprognostic (3.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" 0.7 0.1 0.3 13.0 0.2 1.9 0.2 0.3 0.3 7.2 0.4 142.2 184.0 2.1 1.9 3.3 0.1 1.8 0.7 0.3 0.2 136.5 5.8 0.6 1.3 0.5 0.5 0.3 1.4 0.0 0.0 496.7 0.5 6.1 94.1 0.1 0.6 1.0 0.1 1.4 227.2 3.4 0.3 0.5 18.0 2.1 0.6 2.1 0.2 0.0 3.8 0.8 0.4 0.5 0.0 0.1 0.1 0.4 0.0 0.0 1.0 0.2 0.0 0.0 0.0 3.2 20.5 0.0 2.7 0.0 1.7 6.2 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.3 0.1 6.4 0.2 1.9 0.0 0.0 0.0 7.7 0.3 0.2 2.2 2.5 0.1 0.9 0.0 0.3 0.8 27.1 0.6 0.2 0.1 0.6 0.0 0.2 0.1 0.1 0.2 1.0 0.1 0.2 0.1 31.2 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.3 0.3 0.2 0.5 0.5 0.5 0.3 0.6 0.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.8 272.2 0.0 2.1 0.0 517.5 15.6 0.0 7.1 1.9 0.5 0.4 43.3 0.0 0.1 3.3 63.4 0.5 13.7 4.8 5.7 0.0 0.0 0.0 2.8 0.0 0.1 129.7 2.0 0.0 1.7 18.4 0.0 1.0 0.0 0.0 66.2 0.0 0.0 0.0 0.0 3.7 532.1 0.0 0.0 0.7 957.9 145.2 0.2 0.0 0.0 0.0 0.3 3.7 1.3 0.0 0.1 3.4 0.9 0.0 117.9 0.3 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 APCS "MGC88159, PTX2, SAP" ENSG00000132703 "Amyloid P component, serum" P02743 1 159587826-159588865 "Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "liver: 3629.2" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 4141.9" "Cancer enriched" "Detected in some" 25 "liver cancer: 826.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB007817, HPA053294" Supported "Secreted to blood" NA NA 27700000000 39000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB007817: AB_598185, HPA053294: AB_2682104" "unprognostic (3.19e-3)" "unprognostic (2.30e-2)" 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 47.7 0.2 0.0 0.0 1.3 3629.2 0.1 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 388.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.8 0.0 0.0 0.0 2.7 0.0 45.5 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 57.8 4141.9 0.0 0.0 0.0 0.0 0.0 88.9 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 APELA "ELA, Ende, tdl" ENSG00000248329 "Apelin receptor early endogenous ligand" P0DMC3 4 164877178-164898965 "Predicted secreted proteins" "Angiogenesis, Differentiation, Gastrulation" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.2;prostate: 4.2" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 28.2;Proximal tubular cells: 28.5;Syncytiotrophoblasts: 40.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NTERA-2: 41.7;SuSa: 25.1" "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.97e-2)" "unprognostic (6.97e-2)" "unprognostic (9.83e-4)" "unprognostic (8.92e-3)" "unprognostic (1.43e-3)" "unprognostic (4.50e-2)" "unprognostic (2.21e-1)" "unprognostic (1.71e-1)" "unprognostic (3.38e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-2)" "unprognostic (1.89e-1)" "unprognostic (4.34e-1)" "unprognostic (8.35e-2)" "unprognostic (1.95e-4)" 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 2.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 4.2 0.0 0.2 0.1 0.0 0.1 1.1 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.1 0.0 8.1 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 3.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 5.7 4.3 0.3 0.0 0.0 1.8 0.0 28.2 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 28.5 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 40.9 0.1 0.1 0.0 0.3 APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654956 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;placenta: 54.0" "Cell type enriched" "Detected in some" 7 "Endothelial cells: 68.2" "Group enriched" "Detected in all" 6 "glioma: 44.2;renal cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "HUVEC TERT2: 502.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.50e-1)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (9.32e-4)" "prognostic unfavorable (6.09e-4)" "unprognostic (4.71e-2)" "unprognostic (2.25e-1)" "unprognostic (3.30e-1)" "unprognostic (9.12e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (8.42e-2)" 4.7 9.2 19.9 2.2 21.2 0.0 3.0 19.0 24.0 0.6 6.8 1.0 0.8 0.7 0.3 0.6 1.2 0.4 12.6 15.4 23.8 7.5 1.4 13.4 0.1 30.1 25.9 2.4 0.3 1.0 5.4 54.0 25.4 1.1 0.3 0.3 0.6 0.5 3.7 1.5 0.8 1.9 29.7 0.7 1.2 1.1 33.6 0.3 0.9 1.1 0.2 3.4 0.4 35.8 0.2 0.6 58.5 0.5 1.9 3.6 0.0 0.2 0.0 1.1 1.8 0.0 0.0 0.0 6.2 0.2 2.5 0.0 1.4 14.1 1.0 0.0 0.1 0.0 0.6 0.1 0.2 3.3 1.4 7.7 0.1 7.2 0.0 0.0 502.1 1.7 0.1 1.9 2.6 0.0 0.2 0.7 1.5 0.0 26.8 0.3 0.5 0.9 0.0 0.0 2.0 6.2 0.2 0.1 0.0 0.1 0.1 0.9 86.2 2.1 0.2 36.5 2.1 0.8 0.0 0.0 34.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 21.2 19.0 24.0 15.4 23.8 30.1 25.9 25.4 29.7 33.6 35.8 3.0 0.0 1.3 8.1 0.0 0.1 0.1 0.6 0.0 0.0 0.2 9.4 6.8 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.1 0.1 68.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 0.2 1.3 0.0 0.0 0.3 0.3 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.8 1.9 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.4 0.6 0.0 0.2 0.0 0.1 1.2 0.2 2.9 0.0 0.0 APOA1 ENSG00000118137 "Apolipoprotein A1" P02647 11 116835751-116837622 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Amyloidosis, Atherosclerosis, Cancer-related genes, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 19248.5" "Group enriched" "Detected in many" 21 "Hepatocytes: 27332.1;Proximal enterocytes: 18348.1" "Cancer enriched" "Detected in many" 48 "liver cancer: 4515.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 17 "Hep G2: 3460.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016778, HPA046715" Supported Approved Vesicles,Cytosol "Secreted to blood" NA NA 1450000000000 110000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "CAB016778: , HPA046715: AB_2679768" "unprognostic (1.88e-3)" "unprognostic (4.53e-2)" "unprognostic (7.46e-2)" "unprognostic (4.00e-3)" "unprognostic (3.70e-2)" "unprognostic (1.41e-1)" "prognostic favorable (5.05e-4)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (9.60e-3)" "unprognostic (1.59e-3)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.67e-8)" "unprognostic (3.46e-3)" "unprognostic (1.15e-1)" "unprognostic (6.24e-2)" "unprognostic (9.54e-2)" 3.2 1.4 1.2 3.6 1.2 0.0 2.1 1.1 1.4 0.8 0.8 7.4 1709.3 3.5 0.4 1.1 6.1 1.7 67.2 1.0 1.1 3.7 19248.5 2.7 3.2 1.1 1.1 23.1 2.5 0.0 4.2 1.6 1.1 1.1 0.2 0.1 0.7 1.0 0.8 1.0 4053.7 2.1 1.1 9.0 14.6 384.5 1.2 0.9 3.7 0.2 0.1 0.5 1.5 1.2 0.0 0.0 0.6 0.1 0.0 0.0 15.0 0.0 0.0 0.0 0.0 203.4 0.3 3.1 6.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.1 7.3 1.9 3460.4 0.0 16.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.0 0.2 0.3 15.0 1.2 1.2 0.1 0.5 15.0 20.3 0.0 2.6 5.7 20.7 8.9 0.0 0.0 3.9 0.0 0.1 2.6 0.0 0.4 2.1 0.1 1.2 0.2 4.9 0.0 5.5 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.2 0.1 0.2 0.5 0.0 0.2 0.0 1.2 0.6 0.1 1.2 1.2 1.1 1.4 1.0 1.1 1.1 1.1 1.1 1.1 1.2 1.2 2.0 3.2 3.3 0.3 49.7 0.1 0.5 0.2 0.6 0.5 0.9 0.9 37.0 479.0 1.3 0.0 0.0 0.6 5.1 0.4 0.0 0.1 36.9 15.2 4.3 50.3 1.8 541.9 0.5 1.1 4.2 5.8 17.9 1.7 2.5 419.2 458.7 27332.1 3.3 0.0 0.8 458.8 0.0 681.2 2.0 149.7 22.4 2.1 0.0 0.0 0.0 0.3 3.1 0.0 0.3 0.3 458.2 4.9 1.0 0.1 18348.1 9.0 0.4 0.6 6.6 1.6 13.0 39.8 11.2 0.0 0.6 4.2 35.7 1051.7 175.7 0.3 APOA2 ENSG00000158874 "Apolipoprotein A2" P02652 1 161222292-161223631 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1388 "liver: 36012.6" "Cell type enriched" "Detected in some" 75 "Hepatocytes: 50065.8" "Cancer enriched" "Detected in many" 329 "liver cancer: 11230.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "Hep G2: 16822.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025885, HPA072575" Supported "Secreted to blood" NA NA 115000000000 92000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025885: , HPA072575: " "unprognostic (2.05e-1)" "unprognostic (4.70e-2)" "unprognostic (1.12e-1)" "unprognostic (2.99e-1)" "unprognostic (9.82e-2)" "unprognostic (1.92e-1)" "unprognostic (3.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (4.40e-3)" "unprognostic (3.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.60e-1)" "unprognostic (6.09e-2)" 3.8 1.1 0.7 0.7 0.6 25.9 1.8 0.5 1.4 0.9 1.0 0.7 0.0 0.7 0.1 1.0 1.9 0.0 2.0 0.6 0.8 9.5 36012.6 2.1 0.3 1.1 0.8 0.7 2.0 0.0 1.2 1.3 1.1 0.6 0.5 0.0 0.6 0.0 0.6 0.9 0.9 0.0 0.8 7.7 1.9 1.2 0.7 0.4 0.8 0.0 0.3 0.4 0.8 1.0 0.0 0.6 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 1814.4 0.0 3.6 0.0 0.0 0.0 2.3 1.5 0.0 0.0 0.0 0.0 5.8 10.0 16822.4 0.0 19.3 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.7 0.7 1.5 0.0 1.1 1.3 14.6 0.3 0.0 11.3 0.8 0.0 7.8 0.0 0.2 5.2 0.1 0.0 4.1 0.0 0.1 0.0 0.0 3.8 0.0 5.2 0.0 6.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 0.0 0.7 0.6 0.5 1.4 0.6 0.8 1.1 0.8 1.1 0.8 0.7 1.0 0.0 0.0 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 480.4 0.0 0.0 0.0 0.8 0.0 0.1 1.9 0.0 1.7 0.0 0.0 22.5 0.0 323.6 0.0 0.6 6.4 0.2 0.0 0.0 0.0 0.0 425.9 50065.8 4.7 0.0 0.0 0.2 0.0 665.8 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 9.8 0.0 0.0 0.0 0.0 0.0 1.9 0.9 0.0 0.0 5.6 26.0 0.0 0.0 0.0 APOA4 ENSG00000110244 "Apolipoprotein A4" P06727 11 116820700-116823304 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 3112.4" "Cell type enriched" "Detected in some" 44 "Proximal enterocytes: 10311.5" "Cancer enriched" "Detected in some" 29 "liver cancer: 291.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.7;CACO-2: 8.0;Hep G2: 7.7;NB-4: 7.3;RPMI-8226: 12.5;SH-SY5Y: 10.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001352, HPA002549, CAB068250, CAB068251, CAB068252" Enhanced Approved Vesicles "Secreted to blood" NA NA 61200000000 74000000000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB068250: AB_2665657, CAB068251: AB_2665659, CAB068252: AB_2665658, HPA001352: AB_1078179, HPA002549: AB_1078177" "unprognostic (8.81e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (7.91e-2)" 0.3 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.9 2204.9 1.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 257.2 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3112.4 3.0 0.0 0.1 4.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 3.1 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 77.5 0.0 0.0 0.0 234.3 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.5 0.0 0.0 0.0 10311.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 87.7 0.0 APOA5 "APOA-V, RAP3" ENSG00000110243 "Apolipoprotein A5" Q6Q788 11 116789367-116792420 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 216 "liver: 582.1" "Cell type enriched" "Detected in some" 88 "Hepatocytes: 1249.5" "Cancer enriched" "Detected in single" 489 "liver cancer: 112.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 55 "Hep G2: 35.6" "Not detected" "Not detected" "Secreted to blood" NA NA 114000000 21000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.57e-4)" "unprognostic (4.67e-3)" "unprognostic (5.57e-2)" "unprognostic (2.60e-3)" "unprognostic (2.40e-1)" "unprognostic (2.31e-4)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 582.1 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 35.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 10.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.4 1249.5 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 304.3;liver: 1191.0" "Group enriched" "Detected in some" 8 "Hepatocytes: 2967.4;Proximal enterocytes: 1585.9" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 1079.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793" Supported Supported Vesicles,Cytosol "Secreted to blood" NA NA 1490000000000 100000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "CAB016070: AB_626690, HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" 2.7 0.0 0.1 0.2 0.2 0.1 0.9 0.1 0.1 0.7 0.2 0.4 181.4 0.2 0.0 0.1 0.1 0.5 5.2 0.1 0.3 0.3 1191.0 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.1 0.5 304.3 0.2 0.2 0.5 0.3 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1079.8 0.0 0.6 0.1 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 277.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 1.6 3.5 0.0 104.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 52.8 2967.4 0.1 0.0 0.2 30.8 0.0 69.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.5 1.5 0.0 0.0 1585.9 0.6 0.0 0.0 0.0 1.1 0.2 0.5 0.3 0.0 0.0 0.0 3.9 0.9 14.5 0.0 APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 16232.1" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 33405.9" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 5.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "Hep G2: 576.4;HSkMC: 332.9;K-562: 151.6;SK-MEL-30: 268.0" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" NA NA 20300000000 15000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" 59.2 1998.1 90.3 28.1 133.0 52.2 87.1 83.3 338.1 29.0 73.6 29.1 13.1 11.0 42.0 5.9 21.2 31.0 10.9 75.3 109.8 14.6 16232.1 289.9 140.1 133.2 152.8 56.4 21.4 16.3 23.6 41.7 121.9 14.4 16.7 15.1 35.5 2.2 22.2 73.1 49.1 4.0 92.7 254.9 22.7 18.7 139.2 37.4 36.3 6.1 33.9 23.5 11.3 169.4 2.7 26.5 12.0 5.0 37.1 38.2 111.5 1.3 1.7 4.8 7.3 55.6 49.9 8.4 9.4 1.0 3.2 1.8 15.6 1.9 2.3 0.4 63.5 36.8 4.2 576.4 32.9 27.5 18.1 332.9 2.8 4.8 1.8 9.2 1.3 1.8 151.6 0.8 1.7 3.6 1.5 2.0 112.4 10.4 5.6 6.2 16.0 0.8 7.3 2.0 5.3 3.3 18.9 0.3 268.0 37.7 2.2 98.4 4.2 0.4 1.7 0.2 1.7 4.5 5.4 8.2 0.7 7.4 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.3 90.3 133.0 83.3 338.1 75.3 109.8 133.2 152.8 121.9 92.7 139.2 169.4 22.9 115.4 214.4 2.3 40.6 17.0 4.1 5.8 6.2 2.5 49.8 92.8 0.8 453.2 55.8 1.8 0.0 31.7 1.6 2.4 49.0 4.6 1.2 6.6 128.4 68.9 2.4 768.8 0.3 4.0 341.3 93.0 19.4 5.0 142.6 30.6 432.6 33405.9 4789.8 0.0 0.5 3.2 4.1 867.7 27.3 22.8 270.9 620.5 30.2 3.7 124.5 276.0 0.0 0.0 0.0 3.2 0.3 259.5 1.3 4.2 0.6 16.6 24.4 9.9 19.7 1628.8 24.4 2.0 3.2 3.7 17.8 71.6 46.7 1226.7 2.1 5.0 APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 83 "liver: 9641.4" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1170.2" "Cancer enriched" "Detected in some" 17 "liver cancer: 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 30 "NK-cells: 3.2" "Group enriched" "Detected in many" 4 "Hep G2: 713.0;THP-1: 1354.4" HPA055877 Supported "Secreted to blood" NA NA 43000000000 49000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA055877: AB_2682953" "unprognostic (4.28e-2)" "unprognostic (7.73e-3)" "unprognostic (1.33e-1)" "unprognostic (3.66e-2)" "unprognostic (8.91e-2)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.14e-8)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (9.80e-3)" 1.2 5.4 49.5 1.7 55.2 1.1 5.3 55.1 116.2 4.5 44.7 4.3 41.4 1.2 4.8 2.4 4.3 3.7 0.8 50.7 69.2 16.3 9641.4 34.9 15.8 65.3 64.9 0.4 2.2 6.6 3.0 2.9 74.3 1.3 4.4 2.8 2.4 2.1 1.9 4.3 65.6 0.7 63.3 3.9 2.7 1.1 59.9 3.2 0.9 0.7 9.9 2.2 0.8 75.0 2.9 0.6 0.3 0.4 0.5 0.6 1.3 0.1 0.0 0.0 0.1 2.0 2.8 0.7 0.3 0.0 0.0 2.6 0.0 0.1 0.0 0.7 0.1 123.0 2.7 713.0 0.2 15.4 237.5 0.2 0.3 0.0 0.0 0.3 0.0 0.1 1.7 2.9 0.1 0.8 0.9 126.3 0.5 3.2 0.4 0.8 5.2 1.1 0.0 1.5 0.1 0.1 1.9 0.2 7.7 0.0 0.7 1354.4 0.0 0.3 0.6 0.8 0.8 2.3 0.9 2.2 0.2 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 49.5 55.2 55.1 116.2 50.7 69.2 65.3 64.9 74.3 63.3 59.9 75.0 0.1 0.0 2.3 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.1 11.5 0.0 3.7 0.0 0.1 0.1 0.0 3.9 0.0 0.0 0.0 0.1 0.3 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 26.0 0.0 13.6 1170.2 33.8 0.0 0.0 0.4 0.0 15.5 1.2 0.0 0.0 24.0 7.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 10.0 0.7 0.0 0.1 17.7 32.3 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.4 0.3 1.8 0.0 1.3 0.0 APOC3 ENSG00000110245 "Apolipoprotein C3" P02656 11 116829706-116833072 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 27649.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 84691.9" "Cancer enriched" "Detected in many" 643 "liver cancer: 4021.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "CACO-2: 107.3;Hep G2: 296.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA065365, HPA073918" Supported Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Secreted to blood" NA NA 106000000000 45000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nucleoli, Cell Junctions" "HPA065365: AB_2732733, HPA073918: " "prognostic favorable (3.77e-4)" "unprognostic (2.33e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.60e-2)" "unprognostic (5.21e-2)" 4.1 1.2 0.0 1.0 0.0 0.0 2.5 0.0 0.1 0.4 0.0 7.2 907.0 0.5 0.0 1.1 1.9 0.0 1.6 0.0 0.0 18.2 27649.0 1.4 0.9 0.0 0.0 0.8 2.4 0.0 0.8 0.9 0.0 0.6 0.0 0.0 0.6 0.0 0.6 1.2 1106.7 0.5 0.0 8.0 1.5 1.0 0.0 0.5 0.8 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.0 0.1 107.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 296.2 0.0 10.7 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 2.3 0.2 0.0 0.0 0.0 6.3 3.9 0.0 0.1 1.1 3.8 4.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 67.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 674.9 0.0 0.0 0.0 0.2 0.0 0.0 3.9 0.0 4.2 0.0 0.0 39.7 0.0 823.7 0.0 0.4 1.5 0.1 0.0 0.0 0.0 0.3 707.9 84691.9 1.1 0.0 0.0 264.5 0.0 1107.4 0.0 12.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.0 0.0 0.0 0.0 10473.3 121.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 39.8 0.0 135.5 0.0 APOC4 ENSG00000267467 "Apolipoprotein C4" P55056 19 44942237-44945496 "Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 208 "liver: 629.1" "Cell type enriched" "Detected in single" 37 "Hepatocytes: 3.8" "Cancer enriched" "Detected in single" 15 "liver cancer: 0.7" "Region enhanced" "Detected in single" "white matter: 3.0" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 2.4;TIME: 1.2" "Not detected" "Not detected" HPA062671 Approved "Secreted to blood" NA NA 1000000000 980000000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA062671: AB_2684828" "unprognostic (1.82e-3)" 0.2 0.3 0.4 0.0 0.8 0.5 0.2 0.5 0.9 0.0 0.0 0.1 0.0 0.4 0.7 0.0 0.2 0.3 0.2 0.2 0.5 0.0 629.1 0.2 0.1 0.5 0.4 0.3 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.4 0.1 1.2 0.5 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.1 0.5 0.3 2.4 0.0 0.3 0.0 1.2 0.1 0.0 0.1 0.0 0.1 0.3 0.4 0.0 0.4 0.0 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.0 0.1 0.1 0.4 0.0 0.0 0.4 0.8 0.5 0.9 0.2 0.5 0.5 0.4 0.4 0.3 0.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4485.3;Leydig cells: 2077.4;Melanocytes: 1028.1;Peritubular cells: 994.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 6 "ASC diff: 3507.4;ASC TERT1: 1918.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" 2071.8 84.8 949.6 13.9 1157.3 0.9 5037.8 1174.9 1364.1 620.2 1370.1 144.7 56.0 496.7 155.7 160.0 750.6 213.3 1007.8 952.8 1010.4 49.7 7.1 183.5 24.6 1148.3 1040.5 131.2 212.4 61.9 192.2 350.5 1122.0 419.8 57.2 0.8 1272.3 183.8 1154.9 970.1 88.4 96.2 1027.5 8.2 402.6 75.7 1070.2 113.5 828.8 625.3 20.8 434.4 591.7 1347.6 0.0 2.2 0.5 0.7 3507.4 1918.1 6.1 31.3 7.6 0.1 0.2 222.4 0.4 0.4 0.9 1.8 0.0 0.9 0.4 10.5 0.3 0.3 2.4 0.3 0.2 0.1 12.5 0.3 0.5 91.4 21.0 0.2 17.0 0.3 4.3 0.2 0.2 0.9 5.3 1.3 0.1 0.7 0.5 38.9 0.5 0.1 0.0 0.6 0.0 2.8 0.7 0.5 0.0 34.8 31.8 1.3 67.2 0.1 0.4 0.5 1.4 0.4 0.1 0.2 0.3 9.2 1.0 0.4 420.3 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 949.6 1157.3 1174.9 1364.1 952.8 1010.4 1148.3 1040.5 1122.0 1027.5 1070.2 1347.6 543.2 0.0 11.0 2.9 7.5 145.0 16.0 25.4 46.7 0.0 121.6 138.7 26.9 1.5 81.8 5.5 0.0 5.4 15.9 1.4 0.0 0.4 9.7 16.3 393.7 114.1 46.3 0.0 3.3 0.0 4.2 4485.3 7.7 7.0 0.0 0.0 21.4 0.0 13.3 0.0 2.1 0.7 10.2 0.3 193.2 51.0 2077.4 31.8 1028.1 279.2 1.0 0.0 0.0 300.6 221.5 2.3 0.3 994.5 19.2 25.7 0.0 0.2 128.9 0.0 19.7 100.3 210.7 10.5 4.0 24.1 102.6 5.9 23.5 7.0 0.6 47.3 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 APOF ENSG00000175336 "Apolipoprotein F" Q13790 12 56360568-56362857 "Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 344 "liver: 416.7" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 341.9" "Cancer enriched" "Detected in some" 6 "liver cancer: 34.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "Hep G2: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 18000000000 2200000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (3.55e-2)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" "unprognostic (8.99e-3)" "unprognostic (9.84e-2)" "unprognostic (3.29e-2)" "unprognostic (2.08e-3)" "unprognostic (7.84e-2)" "unprognostic (4.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.68e-3)" "unprognostic (8.55e-2)" "unprognostic (2.42e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-2)" "unprognostic (2.87e-1)" "unprognostic (4.43e-2)" 0.0 0.0 0.3 0.1 0.2 0.2 0.1 0.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 416.7 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.4 4.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.2 0.7 0.3 0.2 0.0 0.3 0.1 0.3 0.0 0.2 1.1 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.3 8.6 0.0 0.0 2.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.4 0.0 16.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 5.0 341.9 0.0 0.0 0.0 0.1 0.0 10.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 563 "liver: 17965.3" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 7680.6" "Cancer enriched" "Detected in many" 232 "liver cancer: 2878.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "Hep G2: 1253.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 247000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB022214: , HPA001654: AB_1078181, HPA003732: AB_1078183" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.39e-7)" "unprognostic (1.26e-1)" "unprognostic (5.99e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.26e-2)" "unprognostic (5.76e-2)" 0.9 0.3 0.0 0.1 0.1 0.4 0.2 0.1 0.2 0.2 0.3 0.8 2.5 0.1 1.0 0.2 0.8 2.8 0.6 0.2 0.0 31.9 17965.3 5.6 0.3 0.2 0.1 0.2 10.9 0.0 0.2 0.4 0.1 0.2 0.7 0.2 0.1 0.3 0.1 0.2 1.0 0.0 0.1 4.3 3.8 0.3 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.0 33.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 60.8 0.0 1.4 0.1 0.0 1.7 1.1 0.0 0.0 0.0 0.4 0.0 2.6 1.4 1253.3 0.0 6.4 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.1 1.4 0.5 0.2 0.0 0.2 0.1 0.6 31.5 0.0 0.8 6.4 0.1 0.0 0.9 0.4 0.0 3.4 0.1 0.2 0.0 0.0 0.0 1.7 0.2 0.1 0.1 0.0 0.8 0.1 2.9 15.3 2.4 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 12.3 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 183.0 0.6 0.0 0.0 0.0 0.0 0.2 3.9 0.8 0.2 0.2 0.0 5.2 0.0 109.7 0.2 2.3 0.6 0.0 0.0 0.1 0.0 0.0 120.0 7680.6 0.5 0.0 0.2 0.4 0.0 182.4 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.8 0.0 0.0 0.0 0.4 25.6 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 8.8 0.0 0.8 0.0 APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 220.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 106.1;Glandular and luminal cells: 216.2;Hepatocytes: 115.6;Pancreatic endocrine cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 243.9;HDLM-2: 166.1;HHSteC: 120.3;RPTEC TERT1: 91.1;RT4: 146.8" "HPA018885, CAB056156" Supported "Secreted to blood" NA NA 1640000000 9200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" 45.3 15.8 8.1 62.5 8.2 4.2 28.4 7.8 9.8 53.8 9.4 32.0 32.7 38.8 17.7 25.7 36.7 69.0 29.5 7.4 8.4 44.5 220.5 59.5 23.1 10.0 8.5 24.8 9.0 4.9 14.1 53.0 9.6 37.5 27.2 0.9 29.7 52.2 11.7 7.1 28.9 65.4 9.0 56.8 64.9 7.9 10.8 24.9 18.0 13.8 23.6 117.7 29.9 8.2 21.6 5.1 0.1 0.6 46.8 44.6 14.2 2.3 9.0 13.7 38.6 0.6 34.4 7.0 243.9 24.8 31.3 5.3 0.0 19.2 3.6 166.1 0.2 6.1 3.2 41.4 120.3 2.4 20.2 8.3 1.7 38.0 0.8 2.0 27.3 1.3 23.8 85.1 2.4 0.2 8.5 2.1 0.6 0.6 0.2 13.6 2.6 3.2 91.1 146.8 1.9 0.1 10.9 5.8 2.1 0.3 0.8 7.8 24.7 29.5 12.4 3.2 1.5 6.5 4.0 1.6 16.0 12.4 4.6 15.6 6.1 5.5 12.6 6.8 10.7 2.6 8.1 11.2 4.3 1.4 4.6 6.3 16.1 22.4 10.3 0.5 5.4 7.2 8.1 8.2 7.8 9.8 7.4 8.4 10.0 8.5 9.6 9.0 10.8 8.2 37.4 57.7 34.3 0.3 7.2 1.7 21.4 73.5 2.8 0.5 6.3 3.0 3.6 15.7 67.1 18.4 2.1 11.0 12.6 31.2 0.0 37.8 0.8 106.1 48.8 41.3 7.7 3.8 0.1 20.0 8.2 27.3 45.9 216.2 11.4 4.3 49.6 115.6 9.1 0.0 0.1 17.7 32.6 15.8 5.3 1.4 27.4 10.9 0.0 7.5 19.4 0.1 36.0 0.0 0.0 105.1 19.9 24.0 15.0 31.2 20.5 2.1 60.5 1.3 6.6 5.5 10.6 0.4 0.4 3.4 2.3 6.7 12.9 1.6 4.6 62.5 APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 32.7;Enteroendocrine cells: 14.9;Glandular and luminal cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.6" "Cell line enhanced" "Detected in some" "BEWO: 18.7;HDLM-2: 109.9;HSkMC: 16.1;K-562: 23.7;SCLC-21H: 47.9" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA049797: AB_2680887, HPA055435: AB_2682816" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (5.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "prognostic favorable (3.45e-4)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.00e-5)" "unprognostic (4.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.18e-2)" "prognostic favorable (2.40e-6)" 13.5 1.0 0.8 6.0 0.8 1.5 14.7 0.9 2.2 4.6 0.5 3.3 4.8 3.9 1.6 4.3 5.9 6.3 5.3 0.9 1.6 8.1 2.0 12.8 4.7 2.5 1.3 3.9 1.0 0.3 9.4 3.3 1.9 14.7 3.4 0.1 5.8 3.4 1.1 4.1 3.8 2.4 1.0 3.2 4.9 0.7 1.1 2.9 3.2 1.3 1.8 12.1 3.6 0.8 0.0 0.0 0.0 0.0 0.2 2.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 109.9 0.0 5.7 0.0 0.0 0.1 0.0 0.2 16.1 0.0 0.0 0.0 0.0 0.8 0.0 23.7 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 1.0 47.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.3 0.1 0.2 1.6 0.0 0.0 0.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.8 0.8 0.9 2.2 0.9 1.6 2.5 1.3 1.9 1.0 1.1 0.8 7.0 0.0 6.7 0.3 0.2 1.3 0.7 1.5 0.0 0.3 4.6 2.2 1.1 1.5 3.4 0.0 0.0 0.5 0.1 0.0 3.9 0.2 0.0 32.7 12.4 6.6 14.9 4.2 0.0 0.7 1.0 10.4 0.0 52.6 2.5 0.0 2.5 0.4 2.3 1.7 0.1 0.8 0.0 6.2 6.5 0.0 2.8 8.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 1.2 0.2 0.3 4.2 0.0 0.0 9.0 1.9 0.0 0.0 0.0 1.1 6.2 1.3 0.5 0.4 1.9 APOM "G3a, NG20" ENSG00000204444 "Apolipoprotein M" O95445 6 31652416-31658210 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 390.7" "Group enriched" "Detected in many" 8 "Hepatocytes: 665.9;Proximal tubular cells: 681.1" "Cancer enriched" "Detected in all" 13 "liver cancer: 185.9" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 12 "Hep G2: 38.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034086, HPA051006" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 7400000000 8200000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "CAB034086: AB_1119033, HPA051006: AB_2681307" "unprognostic (2.76e-3)" "unprognostic (1.69e-2)" "unprognostic (8.66e-2)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (3.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (6.04e-3)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (7.28e-2)" "unprognostic (5.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-1)" "unprognostic (3.20e-2)" 4.9 5.3 0.6 0.1 0.6 2.5 5.2 1.0 0.9 3.7 0.5 3.8 0.6 3.9 1.0 4.1 4.1 0.5 3.5 0.6 0.7 93.7 390.7 2.6 0.6 0.7 0.7 6.2 6.0 0.7 4.7 0.1 0.7 3.8 0.4 0.4 3.5 0.5 7.2 6.4 9.0 0.4 0.7 4.1 5.3 16.0 0.6 1.2 5.5 0.6 1.1 3.3 3.3 0.8 0.5 0.3 0.6 0.7 0.6 0.8 0.0 0.4 1.1 0.4 0.9 3.2 1.0 1.4 0.2 1.1 0.2 0.6 0.4 0.6 0.8 0.8 0.7 0.8 0.3 38.2 1.3 1.7 0.1 1.2 0.4 0.3 1.0 0.5 0.3 0.9 1.2 0.4 1.1 1.1 1.1 0.9 0.5 0.6 0.2 0.8 0.4 1.5 1.1 0.6 0.5 0.2 0.4 0.0 0.5 0.2 1.5 1.2 0.4 0.2 0.1 0.3 0.3 1.1 1.2 1.5 0.2 1.8 0.1 3.0 0.6 0.6 0.3 0.3 0.5 1.1 0.4 0.3 0.5 0.5 0.5 0.6 0.4 0.3 0.7 0.3 0.7 0.3 0.6 0.6 1.0 0.9 0.6 0.7 0.7 0.7 0.7 0.7 0.6 0.8 1.5 0.0 7.4 2.3 9.0 6.4 6.7 6.7 9.1 1.5 6.6 12.4 1.6 12.8 3.0 14.7 4.2 2.0 1.6 4.1 76.3 4.3 60.2 5.2 3.1 2.0 4.2 11.4 0.3 6.9 0.9 4.3 5.1 1.6 5.1 1.8 8.9 665.9 5.4 0.0 0.4 4.9 2.0 14.5 4.2 38.4 9.3 6.1 5.4 0.0 2.5 14.6 1.0 0.5 1.3 6.4 4.9 6.4 7.4 4.2 81.4 681.1 4.6 2.5 0.0 6.2 3.1 33.1 6.6 5.3 6.5 1.2 5.6 4.6 6.5 6.1 APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" 9.0 23.7 55.8 9.0 58.0 7.9 13.3 58.1 76.3 13.1 67.8 17.3 14.4 10.6 19.6 12.6 20.8 9.3 65.1 57.9 58.4 46.5 18.2 8.6 11.7 58.8 57.0 9.4 14.2 62.0 29.2 10.9 57.3 13.7 18.8 52.8 19.7 15.0 45.9 7.7 12.0 12.0 57.0 8.4 17.7 16.8 56.8 14.0 20.3 73.2 11.6 11.2 8.1 57.1 36.5 32.7 53.9 37.8 8.8 19.9 8.3 17.9 21.9 37.4 38.8 19.3 17.0 31.5 21.9 16.5 48.5 29.3 68.5 35.7 41.2 33.4 48.7 15.9 28.6 31.1 20.8 40.9 17.1 22.2 20.7 41.2 30.4 20.1 26.6 38.8 22.9 33.2 35.1 34.6 41.2 43.0 49.2 47.5 52.7 31.5 26.6 75.6 74.1 18.4 36.4 26.5 39.0 36.7 39.7 52.4 63.6 17.9 6.5 23.9 14.6 86.6 27.9 26.3 50.5 28.7 38.5 19.8 35.8 14.8 4.8 1.4 12.6 15.9 16.6 10.8 13.7 12.5 14.0 10.2 10.9 10.7 3.0 10.3 16.0 16.6 14.0 7.7 55.8 58.0 58.1 76.3 57.9 58.4 58.8 57.0 57.3 57.0 56.8 57.1 7.4 16.0 11.5 61.7 11.8 14.0 17.0 74.3 11.4 20.4 14.3 17.0 61.8 21.5 28.3 23.9 14.6 17.2 11.3 12.8 180.0 28.4 25.9 56.0 13.0 10.1 7.2 20.8 61.4 16.0 8.9 11.7 13.3 24.4 3.8 14.2 7.9 13.9 22.7 20.2 76.5 17.0 44.7 14.6 12.0 15.7 11.5 9.9 28.4 74.0 34.2 50.0 8.2 43.7 76.5 10.2 20.0 15.8 14.8 14.1 24.0 80.6 106.9 32.4 6.6 10.8 22.3 26.1 53.2 18.9 7.0 12.4 9.5 17.0 22.3 16.8 APP AD1 ENSG00000142192 "Amyloid beta precursor protein" P05067 21 25880550-26171128 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Apoptosis, Cell adhesion, Endocytosis, Notch signaling pathway" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Alzheimer disease, Amyloidosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 870.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 38.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 38.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000157, HPA001462" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 26000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Vesicles "CAB000157: AB_323833, HPA001462: AB_1078185" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (3.69e-3)" "unprognostic (2.54e-1)" "unprognostic (8.22e-2)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "unprognostic (4.28e-2)" "unprognostic (5.35e-2)" "prognostic favorable (2.79e-6)" "unprognostic (3.77e-2)" "unprognostic (2.46e-1)" "unprognostic (5.23e-2)" "unprognostic (2.08e-3)" 249.9 498.0 413.0 157.4 457.6 134.4 447.5 413.1 572.4 264.2 396.8 357.2 226.4 281.1 293.3 178.6 308.1 350.8 389.0 456.2 405.3 532.5 298.2 279.4 78.9 425.0 481.9 306.2 323.5 278.6 155.4 451.9 448.7 260.6 328.5 209.3 270.7 343.6 107.5 218.6 200.3 379.9 419.7 154.4 213.5 165.6 426.4 159.2 469.9 176.0 78.2 304.9 151.7 523.5 388.7 489.9 538.4 448.5 707.7 869.8 559.8 757.1 1029.2 386.6 449.3 286.4 941.0 0.9 848.3 614.8 505.1 255.6 326.4 921.6 324.4 14.7 253.1 0.8 275.6 204.1 688.0 372.0 19.6 790.4 990.7 456.8 823.0 1584.3 1750.7 158.6 0.8 39.0 614.5 433.1 6.5 4.0 416.2 644.9 418.6 241.2 505.2 325.3 1283.3 270.1 267.3 385.6 824.0 549.0 393.4 720.0 482.4 400.1 1837.1 850.8 350.2 310.4 371.6 232.3 3.1 4.8 690.4 1.6 836.3 1.1 7.5 0.0 0.2 2.2 0.3 0.8 2.2 0.7 5.6 2.2 2.3 0.6 1.5 0.5 1.6 38.1 0.6 3.3 413.0 457.6 413.1 572.4 456.2 405.3 425.0 481.9 448.7 419.7 426.4 523.5 330.2 109.0 39.6 70.5 47.6 181.6 215.6 449.0 306.7 45.2 280.3 199.6 143.2 296.0 214.0 502.1 29.2 472.6 180.7 395.2 56.7 398.7 46.1 78.8 162.2 416.0 162.6 29.2 481.6 180.4 141.2 309.5 164.7 110.7 8.2 100.3 539.7 125.7 76.3 84.1 525.5 303.1 256.3 61.6 79.9 61.8 242.6 69.9 161.9 189.3 89.9 329.9 4.1 423.2 870.8 205.4 223.1 296.8 24.0 187.5 95.2 165.8 164.7 24.5 118.3 336.5 198.5 38.3 86.9 85.9 106.1 552.1 27.0 111.4 283.5 133.6 ARSF ENSG00000062096 "Arylsulfatase F" P54793 X 3041471-3112727 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;kidney: 7.6;skin 1: 5.6" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Distal tubular cells: 1.9;Inhibitory neurons: 4.6;Oligodendrocyte precursor cells: 2.5;Proximal tubular cells: 10.5" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA000549 Uncertain Cytosol "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000549: AB_1845055" "unprognostic (2.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.87e-1)" "unprognostic (5.41e-3)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (9.72e-2)" "unprognostic (4.70e-1)" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (3.59e-1)" "unprognostic (1.23e-1)" "unprognostic (9.76e-2)" "unprognostic (1.48e-1)" 0.0 3.0 2.6 0.0 3.6 0.1 0.2 3.0 2.7 0.4 1.5 0.0 0.0 0.0 1.6 2.6 0.0 0.0 0.0 3.2 2.1 7.6 1.6 0.0 0.0 4.9 2.9 0.0 0.6 0.3 0.0 0.0 3.1 0.1 0.0 0.1 0.2 0.0 0.1 5.6 0.0 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.2 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.6 3.0 2.7 3.2 2.1 4.9 2.9 3.1 2.8 3.0 2.1 0.0 0.0 0.0 9.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.1;Fibroblasts: 10.8;Melanocytes: 21.4;Smooth muscle cells: 6.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 15.7;HaCaT: 31.4;Hep G2: 19.9;hTEC/SVTERT24-B: 30.9;U-87 MG: 39.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA038386, HPA038398" Uncertain Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA038386: AB_10669781, HPA038398: AB_2675995" "unprognostic (6.08e-2)" "unprognostic (1.70e-2)" "unprognostic (9.41e-3)" "unprognostic (4.77e-3)" "unprognostic (1.54e-3)" "unprognostic (2.83e-3)" "unprognostic (2.76e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.06e-1)" "unprognostic (5.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-7)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.19e-4)" 1.2 0.3 1.6 2.3 2.6 0.6 0.4 2.5 2.1 2.7 0.7 1.6 0.6 3.1 0.6 1.8 2.1 1.1 1.3 1.4 1.8 0.7 0.4 4.5 0.3 3.6 2.4 0.4 0.4 0.6 1.0 2.8 3.9 1.7 0.4 0.4 0.5 0.8 0.8 4.8 0.7 2.8 2.6 0.8 0.8 0.4 2.8 0.3 0.2 0.5 0.4 3.8 2.7 5.5 1.0 3.8 1.1 0.0 0.0 0.8 0.0 8.1 12.1 15.7 11.5 1.1 1.8 0.0 3.1 11.5 1.3 31.4 0.2 5.3 5.6 0.0 0.1 0.0 0.4 19.9 1.5 0.0 0.0 0.8 3.4 30.9 0.9 10.7 0.2 0.0 0.0 0.2 2.5 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.1 0.4 0.0 0.2 0.0 6.7 0.9 1.3 11.2 0.0 0.0 0.0 0.3 10.2 0.3 0.0 0.0 0.0 0.0 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.6 2.5 2.1 1.4 1.8 3.6 2.4 3.9 2.6 2.8 5.5 0.1 0.0 0.0 0.3 0.0 12.1 0.0 2.4 0.0 0.1 0.1 0.4 1.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 1.1 10.8 0.0 0.0 4.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.1 0.0 0.8 0.2 0.6 0.0 21.4 0.0 0.0 3.9 0.0 0.0 2.5 0.4 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.3 0.0 1.8 6.6 0.1 0.9 0.9 4.7 1.4 1.1 0.0 0.0 0.0 ARSJ FLJ23548 ENSG00000180801 "Arylsulfatase family member J" Q5FYB0 4 113900284-113979727 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Astrocytes: 44.1;Basal prostatic cells: 60.3;Prostatic glandular cells: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 46.4;HUVEC TERT2: 42.2;LHCN-M2: 42.8;TIME: 53.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036481, HPA036482" Uncertain Enhanced "Actin filaments" "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "HPA036481: AB_2675146, HPA036482: AB_10672356" "unprognostic (1.98e-1)" "unprognostic (1.55e-2)" "unprognostic (4.23e-1)" "unprognostic (5.31e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (6.08e-4)" "unprognostic (2.54e-2)" "unprognostic (2.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (5.31e-2)" "unprognostic (2.20e-1)" "prognostic favorable (2.97e-6)" "unprognostic (2.26e-1)" "unprognostic (8.37e-2)" "unprognostic (1.30e-1)" "unprognostic (2.07e-2)" 1.8 1.3 1.5 1.3 1.1 0.0 1.0 5.0 1.4 4.5 0.2 2.4 0.6 2.0 0.9 3.1 2.8 3.6 2.5 1.2 0.9 2.7 1.7 3.3 0.6 0.9 1.1 2.0 1.1 3.0 0.7 4.3 0.7 3.9 3.3 0.6 5.8 2.2 0.2 0.7 0.7 2.2 0.6 0.2 3.5 0.1 1.9 1.5 0.7 0.6 0.3 3.8 2.1 1.1 2.7 5.3 0.6 0.0 10.1 20.5 0.0 46.4 35.5 29.0 11.3 1.3 3.4 0.0 5.7 22.6 10.3 5.0 0.2 11.7 36.2 0.0 2.1 0.0 4.2 0.0 30.6 0.0 0.0 12.7 11.5 19.7 40.0 20.5 42.2 0.0 0.0 0.0 42.8 0.4 0.0 0.0 1.5 0.0 8.4 0.0 5.1 0.0 38.0 0.0 0.0 1.7 3.1 0.5 2.2 7.5 0.2 0.0 53.6 33.3 8.7 5.0 22.3 0.0 0.0 0.0 16.2 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 5.0 1.4 1.2 0.9 0.9 1.1 0.7 0.6 1.9 1.1 0.7 35.3 9.8 44.1 0.2 2.9 60.3 23.7 15.9 0.2 4.7 2.9 1.3 11.5 10.8 25.8 0.0 0.3 0.1 7.0 0.0 9.2 0.0 6.2 21.1 4.3 23.4 0.0 27.1 0.9 0.2 13.6 4.6 8.2 0.0 0.0 4.2 1.2 0.5 1.7 1.5 17.3 16.2 0.3 1.6 0.3 2.5 0.3 3.6 7.5 0.0 6.8 1.0 3.0 0.5 5.2 5.0 1.5 0.0 49.6 0.1 4.1 4.6 0.2 0.0 8.6 10.5 0.1 0.3 16.9 1.1 0.4 0.6 3.3 4.1 25.6 ARSK "DKFZp313G1735, TSULF" ENSG00000164291 "Arylsulfatase family member K" Q6UWY0 5 95555101-95605102 "Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 19.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042384 Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA042384: AB_10795703" "unprognostic (9.50e-2)" "unprognostic (1.37e-1)" "unprognostic (2.03e-3)" "unprognostic (2.39e-1)" "unprognostic (3.33e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (2.59e-4)" "unprognostic (3.39e-1)" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (7.61e-2)" "unprognostic (2.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.91e-2)" "unprognostic (2.32e-1)" "unprognostic (8.20e-2)" "unprognostic (1.06e-2)" 3.0 3.7 2.1 2.2 2.3 2.3 3.3 2.8 3.0 3.8 2.1 2.7 2.2 3.6 4.2 2.9 3.2 3.1 2.6 2.4 2.1 5.4 3.7 2.9 2.7 1.9 1.9 5.8 4.9 19.1 2.6 5.5 2.3 4.9 2.5 3.6 2.8 4.9 2.3 3.3 2.2 3.0 1.7 2.4 4.2 1.6 2.6 3.7 5.0 2.7 2.0 3.2 3.3 2.2 5.1 3.2 6.6 6.6 32.4 16.8 9.5 15.9 9.2 6.1 12.4 3.9 7.8 6.9 8.1 5.5 10.9 4.6 5.8 10.1 13.3 7.4 8.5 5.5 7.7 6.7 9.4 3.1 4.4 12.4 8.9 9.2 5.9 12.8 10.0 9.3 5.6 7.4 13.7 2.5 8.5 5.9 8.6 1.6 15.3 5.2 10.6 11.0 14.1 1.2 4.7 4.8 9.7 3.1 10.0 9.1 8.9 3.2 18.1 9.6 7.8 15.0 9.9 6.2 11.2 8.4 9.6 8.0 36.5 12.9 1.1 2.1 4.0 1.2 4.7 4.9 4.7 5.4 0.6 5.0 7.0 5.2 0.9 3.3 0.7 2.2 3.9 1.8 2.1 2.3 2.8 3.0 2.4 2.1 1.9 1.9 2.3 1.7 2.6 2.2 6.8 3.2 2.2 9.1 6.6 4.5 6.8 7.4 5.7 7.3 4.4 7.2 4.6 1.5 3.7 7.3 12.5 11.8 6.6 1.9 3.9 4.1 9.2 7.1 10.3 6.2 3.0 10.1 11.0 2.5 47.4 13.6 2.0 5.7 22.9 8.1 6.8 16.5 4.6 10.1 9.7 2.0 10.2 3.2 5.4 2.9 10.8 4.9 5.4 7.5 5.1 12.7 14.4 7.1 10.0 2.6 3.2 11.7 7.1 3.9 3.2 4.8 6.8 10.4 0.0 10.2 10.9 7.4 8.6 5.1 7.0 5.1 9.8 11.8 3.4 2.1 ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 53.3;lymphoid tissue: 19.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Endothelial cells: 12.9;Erythroid cells: 51.3;Hepatic stellate cells: 66.0;Hepatocytes: 30.2" "Group enriched" "Detected in some" 5 "liver cancer: 3.8;pancreatic cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;HEL: 12.1;Hep G2: 7.3;HUVEC TERT2: 27.0" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" NA NA 17000000 "Cluster 85: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" 2.6 2.7 0.3 1.1 0.5 4.6 1.8 0.1 0.4 0.9 0.4 0.6 0.0 0.8 0.3 0.9 2.1 9.0 9.0 0.3 1.1 3.6 53.3 3.2 8.6 0.5 0.4 0.5 2.3 0.3 0.1 7.0 0.4 0.3 0.5 0.3 0.7 0.4 0.3 0.3 0.6 1.1 0.2 19.0 0.3 0.2 0.4 1.9 3.6 0.2 2.3 0.6 0.5 0.6 0.0 0.0 0.2 6.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 7.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.4 0.3 1.1 0.5 0.4 0.4 0.2 0.4 0.6 0.7 0.0 1.1 0.7 0.2 0.3 0.8 0.0 0.0 2.4 0.2 0.1 1.5 15.7 0.0 1.8 12.5 0.9 0.1 0.0 0.0 0.9 0.4 0.2 0.1 12.9 0.0 51.3 0.2 1.9 2.5 1.9 0.0 0.1 0.0 0.0 66.0 30.2 0.1 0.0 0.2 0.0 0.0 4.7 1.3 0.3 1.8 0.1 1.8 0.0 0.0 0.3 1.0 0.0 0.3 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 11.8 6.6 0.5 1.2 0.1 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.4 ART5 ARTC5 ENSG00000167311 "ADP-ribosyltransferase 5" Q96L15 11 3638512-3642316 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 13.4;testis: 29.4" "Group enriched" "Detected in some" 8 "Early spermatids: 18.3;Late spermatids: 18.5;Spermatocytes: 64.9" "Cancer enriched" "Detected in some" 4 "testis cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 13.9" "Not detected" "Not detected" "HPA041637, HPA044099" Uncertain "Secreted in other tissues" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041637: AB_2677589, HPA044099: AB_2678808" "unprognostic (6.32e-2)" "unprognostic (3.26e-5)" "unprognostic (4.09e-3)" "unprognostic (2.06e-4)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (2.22e-2)" "unprognostic (1.21e-2)" "unprognostic (5.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.85e-4)" "unprognostic (3.10e-3)" "unprognostic (3.46e-2)" "unprognostic (1.96e-1)" "unprognostic (3.18e-1)" 0.7 0.2 0.3 0.0 0.3 0.0 1.0 0.3 0.5 4.1 0.6 0.3 0.0 3.6 0.7 0.5 1.5 1.4 1.8 0.3 0.8 0.8 0.9 0.9 0.1 0.4 0.4 8.3 0.4 2.9 0.7 0.1 0.6 1.1 0.0 0.6 1.6 0.9 13.4 0.5 0.2 1.1 0.3 0.0 0.5 29.4 0.4 0.3 2.8 10.5 0.0 0.7 2.2 0.3 0.0 0.1 1.6 2.0 0.0 0.0 3.2 0.2 1.6 0.7 1.8 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.5 0.0 0.4 0.0 2.2 0.0 0.3 0.1 0.0 0.0 1.4 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.0 0.2 0.3 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.0 13.9 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.3 0.8 0.4 0.4 0.6 0.3 0.4 0.3 0.1 0.0 1.8 0.0 0.0 0.3 2.2 0.0 2.8 0.8 0.3 1.3 2.5 0.0 0.6 0.0 0.0 0.6 0.0 0.1 0.0 0.6 18.3 0.1 0.2 0.4 0.0 0.0 0.0 0.2 0.5 1.3 0.0 0.2 0.0 3.3 0.0 1.8 0.1 0.0 0.0 0.2 0.0 0.3 0.0 18.5 3.4 0.1 0.0 1.0 0.0 3.6 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.8 0.0 0.6 0.0 0.9 0.0 1.3 0.2 64.9 3.9 0.1 0.3 2.9 0.0 1.2 0.0 0.3 ARTN "ENOVIN, EVN, NBN" ENSG00000117407 Artemin Q5T4W7 1 43933320-43937240 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Urothelial cells: 51.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "A-431: 61.9;HaCaT: 62.8;HBEC3-KT: 57.0;hTCEpi: 22.7;hTERT-HME1: 15.9" "Region enriched" "Detected in single" 9 "olfactory bulb: 3.3" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (3.07e-3)" "unprognostic (1.18e-1)" "unprognostic (3.08e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.34e-1)" "unprognostic (1.70e-1)" "unprognostic (9.59e-6)" "unprognostic (2.35e-2)" "unprognostic (3.04e-2)" "unprognostic (1.48e-3)" "unprognostic (1.53e-1)" 2.8 0.9 1.5 0.9 1.1 0.8 1.8 2.9 2.3 4.5 1.2 2.4 0.4 3.2 3.4 3.8 2.8 0.9 2.0 1.2 1.0 4.1 0.7 2.3 0.3 4.4 2.2 2.1 2.8 6.7 6.6 7.4 4.5 8.3 1.6 1.7 1.5 8.1 0.7 1.0 1.2 1.3 1.0 0.7 1.7 2.4 5.4 0.3 1.4 0.3 0.3 2.3 4.7 1.0 61.9 1.5 1.2 0.9 0.2 0.3 0.2 2.8 0.5 2.3 2.5 0.4 1.4 0.8 0.4 0.9 0.8 62.8 0.0 57.0 0.6 0.2 2.1 1.0 7.6 0.1 0.0 0.4 1.3 0.0 22.7 1.1 15.9 10.6 0.0 1.1 0.7 2.1 0.2 4.3 0.2 4.0 5.4 0.0 2.6 1.4 0.0 0.9 0.3 1.3 1.4 0.5 0.4 0.1 1.4 1.1 10.2 10.4 0.6 1.2 0.5 0.5 2.8 6.7 5.5 0.9 8.8 3.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 2.9 2.3 1.2 1.0 4.4 2.2 4.5 1.0 5.4 1.0 0.1 0.0 0.0 0.0 0.1 0.0 4.3 2.3 0.0 1.8 2.3 0.5 0.8 0.0 2.8 0.0 0.0 0.1 0.3 2.8 3.9 0.1 8.4 1.6 0.3 0.2 0.0 0.0 0.7 0.2 0.0 0.3 0.0 1.9 0.0 3.2 0.0 0.0 0.1 0.0 1.2 1.0 0.0 0.0 0.5 2.6 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.4 0.0 12.1 0.0 1.6 0.7 4.6 0.0 0.0 4.0 4.3 0.0 0.0 0.0 0.0 0.1 0.8 0.7 51.5 ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1092.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1107.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.2;intermediate monocyte: 55.5;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.2" "Cell line enriched" "Detected in some" 29 "Hep G2: 493.2" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" NA NA 10000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" 2.6 1.5 7.7 3.7 7.8 2.5 1.8 17.0 10.9 1.6 7.0 1.2 2.2 1.3 0.6 1.7 1.8 2.9 1.1 7.9 7.6 1.4 1092.3 3.9 1.3 8.0 8.2 1.1 0.9 7.0 2.9 0.5 8.3 1.7 0.5 4.8 0.9 0.3 1.5 4.4 1.4 1.3 6.0 4.8 1.4 26.5 7.8 0.4 5.8 0.4 0.3 1.7 1.5 8.7 0.3 0.7 9.2 4.2 0.0 0.2 0.8 0.8 0.9 0.9 1.6 16.8 0.5 0.3 1.1 0.2 0.4 0.2 0.3 0.2 0.4 0.3 0.8 1.2 1.4 493.2 0.1 0.8 1.7 1.2 0.2 0.5 0.1 0.6 8.4 7.4 1.1 0.6 0.5 0.4 0.7 1.2 1.7 0.2 0.4 0.9 3.5 0.2 0.1 0.7 0.6 3.5 0.7 0.3 0.6 1.5 0.5 0.2 1.2 0.9 3.4 0.7 0.4 0.2 0.3 0.5 0.6 0.4 0.3 10.0 115.2 0.4 0.2 55.5 1.1 0.5 0.2 0.2 41.2 0.5 0.3 0.4 3.3 0.5 14.9 1.8 0.3 36.7 7.7 7.8 17.0 10.9 7.9 7.6 8.0 8.2 8.3 6.0 7.8 8.7 6.0 0.0 4.7 2.9 2.6 3.2 1.7 2.0 3.4 37.8 5.6 6.0 1.5 55.8 2.0 3.7 160.6 3.6 2.9 1.4 3.9 0.9 235.4 4.2 3.6 13.2 15.6 16.8 4.6 0.2 3.7 1.9 3.6 16.5 0.0 5.1 27.5 1107.9 39.9 15.2 4.8 2.3 2.0 97.4 11.9 115.8 2.5 52.6 0.0 1.9 77.2 3.6 0.0 2.0 0.6 0.3 1.3 1.2 0.0 0.9 0.2 6.8 1.6 42.3 0.0 0.8 1.9 6.5 9.7 9.9 4.8 12.4 1.4 1.6 1.3 2.4 ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 14.8;heart muscle: 28.0;ovary: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.4;dendritic cells: 44.1;Hofbauer cells: 15.1;Leydig cells: 12.5;Peritubular cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 356 "plasmacytoid DC: 134.8" "Lineage enriched" "Detected in single" 356 "dendritic cells: 134.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.2;HSkMC: 2.4;SK-MEL-30: 1.9;U-698: 1.9" "Not detected" "Not detected" HPA048636 Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" 1.4 0.6 0.2 0.0 0.5 0.3 2.4 0.1 0.4 4.2 0.0 0.5 0.0 2.0 14.8 0.1 4.0 0.1 28.0 0.1 0.1 0.9 1.3 0.3 0.4 0.2 0.1 41.7 0.1 0.0 0.6 0.2 0.6 1.5 0.0 0.3 0.7 0.2 0.9 5.7 0.8 0.0 0.0 0.3 0.3 1.5 0.2 0.2 0.3 1.2 0.5 0.5 1.1 0.3 0.0 1.1 0.4 0.4 0.2 0.7 0.1 0.1 0.0 0.0 0.0 3.2 0.0 1.2 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.7 0.3 0.5 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.1 0.0 0.7 0.6 0.9 0.0 0.3 0.2 1.7 0.0 0.1 0.6 0.3 0.3 1.4 0.0 0.1 0.2 0.2 0.0 0.2 1.9 0.5 0.3 0.2 0.3 0.5 0.5 0.0 0.3 0.4 0.4 1.9 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 134.8 0.0 0.6 0.2 0.5 0.1 0.4 0.1 0.1 0.2 0.1 0.6 0.0 0.2 0.3 0.4 0.0 0.6 1.3 0.8 2.5 0.0 0.0 0.0 0.0 0.3 0.5 27.4 0.0 0.0 0.0 0.0 0.2 44.1 0.0 1.9 0.0 1.1 0.3 9.2 1.2 0.0 0.0 2.1 0.0 0.2 5.6 0.0 0.4 0.0 0.2 2.5 5.8 15.1 0.0 1.8 0.0 0.0 0.8 7.0 1.7 12.5 2.1 1.8 1.0 0.3 0.0 0.0 2.5 2.5 0.1 0.0 10.5 0.0 0.1 0.0 8.3 0.0 0.0 6.6 0.1 0.6 1.7 1.9 0.2 3.1 0.8 0.6 1.0 0.0 0.1 ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.2;Fibroblasts: 94.6;Microglial cells: 24.4;Sertoli cells: 39.5;Smooth muscle cells: 73.5;Suprabasal keratinocytes: 27.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 16.0;BJ hTERT+: 5.7;HHSteC: 23.2;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" 29.6 7.6 1.2 5.7 1.7 0.1 11.8 2.3 2.0 40.9 0.9 25.5 9.6 69.6 9.7 10.1 16.9 65.9 95.3 1.2 1.2 11.2 41.1 14.3 3.0 1.3 1.2 7.1 13.4 3.8 2.5 4.3 1.6 4.7 11.3 0.2 3.2 11.7 7.8 12.1 17.6 110.5 1.0 2.3 12.0 1.2 1.8 2.5 11.1 19.8 5.5 13.4 5.0 1.7 0.1 0.0 0.0 0.0 1.4 16.0 0.2 2.6 5.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 23.2 0.2 0.0 4.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 1.2 1.7 2.3 2.0 1.2 1.2 1.3 1.2 1.6 1.0 1.8 1.7 12.9 0.0 1.1 0.3 0.1 67.2 0.1 0.0 0.0 0.4 0.4 0.1 8.5 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 4.2 6.8 0.0 0.0 2.0 0.0 0.1 94.6 0.5 0.2 1.3 0.1 13.9 0.4 0.2 0.0 1.7 0.0 0.0 0.0 13.5 0.6 5.9 0.8 14.2 24.4 0.0 0.1 0.0 1.5 1.1 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.7 0.6 39.5 4.3 73.5 0.0 0.1 0.3 27.0 0.0 1.7 0.3 0.0 0.0 ATRN "DPPT-L, MGCA" ENSG00000088812 Attractin O75882 20 3471018-3651118 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 101.6;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 89.5;Oligodendrocytes: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008853 Approved Approved Cytosol "Secreted to blood" NA NA 27000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA008853: AB_1078248" "unprognostic (6.42e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-1)" "unprognostic (5.27e-2)" "unprognostic (1.65e-1)" "unprognostic (3.99e-2)" "unprognostic (4.28e-1)" "unprognostic (3.40e-2)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.19e-6)" "unprognostic (3.71e-2)" "unprognostic (9.49e-2)" "unprognostic (2.77e-1)" "unprognostic (3.91e-2)" 12.8 19.1 10.5 10.3 12.2 8.6 17.2 9.3 13.2 16.5 8.9 11.8 55.8 11.8 15.6 10.4 11.7 13.9 19.1 13.4 12.2 23.9 62.8 14.4 7.5 8.0 8.7 14.0 20.2 40.1 8.7 22.6 9.0 12.8 12.3 24.2 13.9 13.2 11.6 14.9 33.4 14.9 11.3 13.8 24.0 16.6 10.8 7.8 32.3 14.2 9.6 15.7 9.1 15.8 40.8 37.6 21.9 18.4 37.9 61.5 28.1 26.6 37.5 27.4 23.1 16.3 27.1 0.0 17.5 37.4 33.8 55.6 15.0 58.1 36.4 4.5 12.8 12.7 10.0 35.1 22.8 27.2 8.3 33.1 46.0 29.0 27.8 34.3 36.0 8.7 20.2 19.2 27.0 11.7 11.1 10.4 14.7 13.2 22.3 9.2 50.9 30.8 24.8 28.5 12.9 20.2 26.7 48.9 36.3 21.3 26.2 25.5 44.7 29.0 17.0 30.8 26.6 13.4 20.1 0.1 17.9 17.9 29.6 3.6 3.2 2.0 2.3 2.8 1.0 1.4 1.2 1.4 2.8 1.7 2.0 1.7 0.0 1.5 3.1 2.6 1.8 1.0 10.5 12.2 9.3 13.2 13.4 12.2 8.0 8.7 9.0 11.3 10.8 15.8 11.1 16.0 10.4 70.2 5.8 6.4 4.3 14.1 6.8 22.5 9.9 8.8 12.6 20.0 10.3 11.0 37.5 7.4 8.0 6.5 1.9 8.2 7.1 9.9 15.1 11.1 9.6 7.4 101.6 14.6 8.4 12.7 20.4 11.8 7.0 39.3 17.9 50.9 10.4 37.0 101.1 10.7 4.1 14.2 6.7 5.4 12.5 11.5 7.2 64.6 10.1 11.8 5.2 89.5 85.7 10.0 14.3 7.9 11.4 7.0 34.6 7.3 10.2 20.1 32.9 14.3 10.9 21.3 21.1 8.5 7.2 5.1 5.8 21.0 12.6 5.2 AVP "ADH, ARVP" ENSG00000101200 "Arginine vasopressin" P01185 20 3082556-3084724 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Hormone, Vasoactive, Vasoconstrictor" "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1308 "brain: 7951.2" "Group enriched" "Detected in some" 6 "Late spermatids: 26.2;Proximal tubular cells: 46.6" "Not detected" "Not detected" "Region enriched" "Detected in many" 131 "hypothalamus: 7951.2" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enriched" "Detected in single" 13 "NB-4: 2.3" "Region enriched" "Detected in many" 10 "hypothalamus: 232.9" "Group enriched" "Detected in many" 337 "basal ganglia: 815.6;hypothalamus: 743.3" "CAB025318, HPA071892" Enhanced Supported "Secreted to blood" NA NA 19300 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB025318: , HPA071892: AB_2732190" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" 0.3 0.3 24.5 0.0 7.0 0.8 0.2 1.2 60.5 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.6 7951.2 1.5 0.3 0.1 0.0 0.2 0.7 0.1 0.1 0.0 6.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 1.7 0.1 0.0 1.0 0.0 0.0 1.4 10.8 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 24.5 7.0 1.2 60.5 1.6 7951.2 0.2 0.7 0.3 1.0 10.8 0.5 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 5.7 0.0 0.2 0.0 0.0 4.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 5.0 0.2 0.0 0.0 0.0 0.3 26.2 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.3 46.6 0.0 0.1 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "bone marrow: 1578.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.5;Breast myoepithelial cells: 4.6;Endometrial ciliated cells: 8.9;Erythroid cells: 8.8;Respiratory ciliated cells: 4.5;Skeletal myocytes: 5.7;Spermatogonia: 6.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cell line enriched" "Detected in some" 15 "THP-1: 659.5" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 320000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA055851: AB_2682943, HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" 0.8 0.2 0.4 0.0 0.4 1578.1 1.5 0.2 0.9 0.2 0.2 0.2 0.0 0.5 0.0 0.1 1.4 0.0 2.0 0.4 0.3 0.4 2.8 15.9 0.6 0.3 0.3 0.2 0.2 0.0 0.9 0.9 0.4 0.4 0.0 0.0 2.6 0.0 0.5 0.6 0.2 0.0 0.2 33.1 0.2 2.4 0.4 3.1 0.5 0.0 0.0 0.3 0.2 0.3 1.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 44.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.4 0.6 659.5 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.6 0.0 34.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.1 0.4 0.4 0.2 0.9 0.4 0.3 0.3 0.3 0.4 0.2 0.4 0.3 3.5 0.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.0 4.5 4.6 0.7 0.0 0.5 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 8.9 1.2 1.0 0.0 8.8 0.8 0.0 0.3 0.8 0.0 2.3 0.0 0.1 0.0 0.4 3.2 0.0 1.4 0.4 0.0 3.7 0.4 0.7 0.0 3.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.2 0.0 4.5 0.0 0.0 5.7 1.2 0.1 6.4 0.9 0.1 0.0 1.0 0.0 0.6 0.0 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711487-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 31919.3;NK-cells: 24726.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1790000000 2100000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 3160.2 3214.7 697.6 5686.5 705.1 7839.2 2606.9 711.8 1145.0 2539.9 789.6 5139.0 5180.7 2192.2 1735.6 2283.9 1648.3 4948.8 2327.2 651.0 769.9 2462.6 6206.2 6159.2 9311.8 889.5 763.2 1945.7 1310.9 1940.5 318.4 3502.0 815.3 2345.0 5593.5 139.3 5657.1 1784.5 931.7 3015.6 5693.3 2545.3 838.3 7896.1 4878.2 615.6 771.9 4217.4 2340.8 2026.5 5333.4 5753.1 549.4 909.5 1735.4 378.9 226.0 633.6 4348.7 4719.4 1662.5 2045.5 4961.9 3609.7 6561.4 425.3 5417.9 554.8 2567.9 1948.8 2410.2 2537.0 497.2 878.7 1226.2 4762.2 435.9 2956.9 2263.6 600.3 3609.3 2074.5 3328.6 2735.9 609.8 1075.7 1044.4 2442.6 1884.1 965.4 611.9 3649.1 2195.5 476.9 1518.4 3213.8 206.5 629.8 1014.3 2240.2 1926.6 4789.2 2425.5 3486.4 254.1 179.1 1288.4 1571.2 1338.5 394.3 655.3 6180.6 2548.7 4531.4 676.5 5389.2 2193.3 4771.7 7118.6 1683.1 5384.6 3783.6 2567.3 48105.4 18117.1 33178.9 20639.1 17775.0 20836.8 15768.0 23783.0 22245.1 9978.8 11988.4 17122.9 22791.8 50453.6 18779.6 19034.9 12052.6 29659.1 56957.2 697.6 705.1 711.8 1145.0 651.0 769.9 889.5 763.2 815.3 838.3 771.9 909.5 12048.3 3387.8 3505.1 28.7 8472.8 7843.7 3197.1 8420.8 1628.8 33.3 2399.5 2015.2 1068.8 3593.1 5347.4 2100.3 27.1 1354.6 14028.8 8753.6 1038.9 13898.6 43.1 2073.7 2414.0 8385.6 2266.0 2087.2 7.3 9034.5 4397.5 3691.1 1981.7 2282.2 3029.5 1270.6 6835.7 3832.6 11985.7 5.0 22.0 5982.6 8701.4 12536.8 14507.0 158.8 3018.0 10687.9 6744.8 368.2 31919.3 322.0 24726.3 95.0 129.2 10115.7 7085.6 1688.8 11026.6 5300.4 18327.7 3122.5 8367.9 52.5 4016.7 2055.2 4107.1 64.2 72.1 1541.4 8619.8 804.8 14266.2 3229.8 3063.4 8248.6 B3GAT1 "CD57, GlcAT-P, HNK-1, LEU7, NK-1" ENSG00000109956 "Beta-1,3-glucuronyltransferase 1" Q9P2W7 11 134378504-134412242 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 195.2" "Cell type enhanced" "Detected in some" "Astrocytes: 27.4;Bipolar cells: 37.0;Excitatory neurons: 37.2;Inhibitory neurons: 30.4;Muller glia cells: 116.2;Oligodendrocyte precursor cells: 33.2;Oligodendrocytes: 77.8" "Group enriched" "Detected in some" 11 "glioma: 10.8;prostate cancer: 3.5;thyroid cancer: 4.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Cell line enhanced" "Detected in some" "AF22: 23.1;HMC-1: 25.3;NTERA-2: 22.1;SH-SY5Y: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002500, CAB010893, HPA069468, HPA074314" Enhanced Enhanced Vesicles "Secreted in brain" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB002500: AB_563601, CAB010893: AB_1078474, HPA069468: AB_2686138, HPA074314: " "unprognostic (6.72e-2)" "unprognostic (3.97e-4)" "unprognostic (2.13e-2)" "unprognostic (1.40e-3)" "unprognostic (5.52e-2)" "unprognostic (2.60e-3)" "unprognostic (6.30e-2)" "unprognostic (1.96e-2)" "unprognostic (8.74e-2)" "unprognostic (2.72e-1)" "unprognostic (1.57e-3)" "unprognostic (1.58e-1)" "unprognostic (9.34e-3)" "unprognostic (3.87e-3)" "unprognostic (2.42e-1)" "unprognostic (4.07e-2)" "unprognostic (2.26e-2)" 0.2 4.2 146.6 0.4 135.6 1.0 3.9 114.3 195.2 0.4 32.5 0.9 0.5 1.4 0.2 0.2 0.4 0.3 0.3 191.8 85.5 1.8 5.8 0.6 2.1 133.6 145.2 0.2 0.4 0.0 4.5 0.1 118.9 2.8 0.1 23.8 1.2 0.4 0.1 0.5 0.6 0.1 115.0 1.4 34.9 0.9 133.6 0.4 6.2 0.2 0.4 0.7 0.3 176.0 0.0 0.0 23.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.7 3.9 0.0 0.9 1.2 1.6 0.0 0.0 0.0 0.7 0.1 0.2 0.0 0.1 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.1 22.1 1.1 0.0 0.4 0.0 1.7 0.0 0.1 3.1 8.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.0 2.3 0.1 0.0 0.1 0.0 0.1 0.2 0.1 5.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 146.6 135.6 114.3 195.2 191.8 85.5 133.6 145.2 118.9 115.0 133.6 176.0 0.1 0.0 0.0 27.4 0.1 0.0 0.0 0.0 0.0 37.0 1.2 0.8 1.1 2.8 0.0 0.0 4.2 0.0 14.4 0.1 0.0 0.0 1.8 0.1 0.1 0.4 1.8 0.4 37.2 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 4.7 0.1 23.5 30.4 0.0 0.0 0.3 0.0 3.9 0.0 0.2 0.0 3.7 0.0 116.2 15.5 33.2 77.8 0.0 0.0 0.4 7.5 0.9 0.0 1.9 0.0 8.6 0.0 0.1 0.2 0.2 0.8 0.0 0.0 0.1 3.8 0.0 0.0 0.3 BCAN "BEHAB, CSPG7, MGC13038" ENSG00000132692 Brevican Q96GW7 1 156641390-156659532 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 164.7" "Group enriched" "Detected in some" 8 "Astrocytes: 136.1;Horizontal cells: 109.4;Melanocytes: 186.7;Oligodendrocyte precursor cells: 288.0" "Cancer enriched" "Detected in many" 5 "glioma: 348.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "basophil: 7.8" "Lineage enriched" "Detected in single" 24 "granulocytes: 7.8" "Cell line enhanced" "Detected in many" "HDLM-2: 76.7;K-562: 108.3;U-266/70: 63.3;U-266/84: 133.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007865, CAB025862" Enhanced Supported "Secreted in brain" NA NA 120000 "Cluster 34: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025862: , HPA007865: AB_1078299" "unprognostic (7.14e-2)" "unprognostic (3.14e-1)" "unprognostic (1.95e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (4.80e-2)" "unprognostic (6.87e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-2)" "unprognostic (9.47e-3)" "unprognostic (2.76e-2)" "unprognostic (8.54e-2)" "unprognostic (5.40e-1)" "unprognostic (1.90e-1)" 0.2 8.4 155.0 0.6 119.5 0.0 0.2 108.3 164.7 2.7 38.3 2.2 7.0 5.9 15.4 0.6 4.0 3.4 0.5 133.1 104.8 0.2 0.1 0.4 0.3 107.5 100.0 0.2 0.1 1.7 2.8 0.7 103.4 0.2 0.0 4.1 1.6 1.8 0.6 15.6 7.8 2.0 94.3 0.5 2.2 1.2 113.7 0.1 0.2 0.0 0.0 0.9 0.9 116.3 44.2 28.4 0.2 8.1 0.0 0.0 11.9 0.4 0.0 0.0 0.0 1.1 21.0 0.1 45.8 0.0 1.0 30.9 0.3 0.0 0.0 76.7 2.9 8.0 20.9 25.6 0.0 3.0 7.3 0.0 0.0 0.0 0.0 1.0 0.0 3.8 108.3 21.0 0.0 12.6 0.1 0.1 2.2 22.2 4.2 0.1 46.7 0.1 0.0 5.4 0.2 0.8 0.1 0.0 43.8 2.2 0.2 2.8 8.8 0.1 24.7 8.7 11.8 63.3 133.2 0.2 8.5 20.4 3.4 7.8 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.0 119.5 108.3 164.7 133.1 104.8 107.5 100.0 103.4 94.3 113.7 116.3 0.2 0.0 0.0 136.1 0.0 6.9 0.0 0.0 0.0 6.0 0.2 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.1 2.9 0.1 1.8 0.7 1.8 0.0 16.8 0.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.5 109.4 20.2 0.1 0.0 0.0 1.9 6.9 0.3 0.1 186.7 9.4 0.0 2.1 1.0 288.0 3.5 0.8 0.1 0.0 0.0 0.3 0.1 0.4 0.0 3.2 0.0 0.2 1.7 5.4 6.5 0.0 1.7 0.0 0.2 0.0 0.0 0.0 BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837462 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 525.1" "Group enriched" "Detected in many" 9 "Hepatocytes: 420.3;Oligodendrocyte precursor cells: 210.1" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "Karpas-707: 785.6" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" NA NA 9400000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" 30.4 11.6 9.3 2.7 7.4 0.0 4.7 7.5 12.0 22.0 5.0 36.1 4.7 41.0 24.3 25.8 36.2 6.0 9.7 7.9 7.3 4.9 525.1 10.9 0.2 7.9 9.4 3.7 2.3 0.1 1.8 0.0 7.8 12.5 16.1 8.8 1.9 32.3 2.7 8.7 10.6 29.7 7.4 5.9 3.5 1.3 12.2 2.9 1.3 5.1 0.1 11.3 5.1 9.4 0.0 2.1 82.1 0.1 0.2 0.0 0.1 0.0 1.5 0.6 7.3 0.0 0.1 0.3 30.7 0.0 0.0 0.5 5.7 0.4 5.8 0.4 0.8 0.0 0.0 0.0 6.3 0.2 0.4 23.5 1.4 0.0 8.1 25.3 3.6 30.0 0.0 785.6 0.0 0.0 0.0 0.1 2.1 0.0 0.8 0.0 28.4 67.3 0.7 0.0 0.0 0.8 0.1 0.0 46.5 0.0 34.0 0.2 0.0 19.3 0.5 0.0 8.3 3.5 0.0 1.6 8.2 0.2 84.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 7.4 7.5 12.0 7.9 7.3 7.9 9.4 7.8 7.4 12.2 9.4 5.8 0.0 0.0 1.0 0.7 5.5 0.9 0.0 1.8 1.4 0.0 0.1 9.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.6 0.0 0.7 3.4 0.0 8.0 3.0 0.0 0.0 22.0 0.5 0.0 0.0 0.2 8.9 420.3 0.1 1.7 10.5 0.4 0.0 4.7 1.5 8.7 2.1 0.3 19.6 3.7 0.0 31.7 0.0 210.1 16.1 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 1.2 0.0 0.8 6.5 0.3 0.3 0.6 3.4 0.0 1.1 0.1 0.0 0.1 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BGLAP OCN ENSG00000242252 "Bone gamma-carboxyglutamate protein" P02818 1 156242184-156243317 "FDA approved drug targets, Predicted secreted proteins" Biomineralization "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 19.9;choroid plexus: 10.8;intestine: 8.5" "Cell type enhanced" "Detected in some" "Ionocytes: 4.1;Melanocytes: 3.6;Plasma cells: 2.8;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "NK-cell: 1.8;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 17 "dendritic cells: 1.6;NK-cells: 1.8" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 8.3;U-87 MG: 5.4" "Region enriched" "Detected in single" 9 "olfactory bulb: 7.8" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 15500000 2200000 "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.50e-2)" "unprognostic (4.49e-2)" "unprognostic (3.82e-4)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (8.44e-5)" "unprognostic (2.63e-2)" "unprognostic (6.54e-2)" "unprognostic (5.64e-2)" "unprognostic (2.00e-1)" "unprognostic (1.53e-3)" "unprognostic (4.70e-2)" "unprognostic (9.67e-6)" "unprognostic (3.02e-2)" "unprognostic (1.72e-1)" "unprognostic (4.34e-2)" "unprognostic (8.64e-3)" 0.7 0.5 12.7 0.6 13.9 0.9 0.6 13.3 19.9 1.7 10.8 8.5 0.6 1.4 1.1 0.7 1.4 0.6 0.8 12.3 12.7 1.1 1.6 0.6 0.4 14.6 13.4 1.9 0.8 0.2 1.1 0.4 13.5 2.0 1.8 0.2 1.7 0.7 0.5 1.7 2.3 1.8 14.0 1.9 0.8 0.4 13.4 0.3 1.4 0.0 0.2 0.8 1.0 14.7 0.1 1.5 0.7 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.5 0.5 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.5 0.1 0.2 0.4 0.0 0.0 0.7 0.6 0.1 0.3 0.7 0.1 0.4 1.8 0.0 0.2 0.6 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.7 1.1 1.4 5.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.6 0.0 0.0 12.7 13.9 13.3 19.9 12.3 12.7 14.6 13.4 13.5 14.0 13.4 14.7 0.6 0.0 0.0 0.0 0.6 1.5 1.0 1.0 0.6 0.2 1.1 0.9 0.0 0.0 1.0 0.0 0.0 0.5 0.2 0.1 0.0 0.1 0.1 0.3 0.4 0.6 0.0 0.0 0.0 0.2 0.3 1.0 0.5 0.5 0.0 1.1 1.1 0.2 0.2 0.0 0.0 0.9 4.1 0.0 0.8 0.2 1.5 0.5 3.6 0.0 0.4 0.4 1.0 0.0 0.0 0.0 1.1 0.4 2.8 0.7 0.3 2.0 0.3 0.6 6.6 0.5 0.3 0.4 0.8 0.6 1.3 0.4 0.6 0.8 0.8 0.7 BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 795.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 223.5;Peritubular cells: 782.7;Sertoli cells: 1485.7;Smooth muscle cells: 401.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 312.6;BJ hTERT+: 400.8;fHDF/TERT166: 568.9;HSkMC: 283.9;hTEC/SVTERT24-B: 235.2;HUVEC TERT2: 561.2;U-138 MG: 249.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 3300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" 165.8 213.0 54.1 93.1 57.6 0.3 118.0 51.2 91.5 371.0 69.5 69.3 22.0 234.4 83.7 45.8 143.7 326.1 795.8 56.1 48.7 396.5 347.9 477.3 42.4 50.6 50.8 94.9 67.9 26.6 144.1 199.1 53.2 184.2 24.8 1.1 107.7 135.5 32.4 118.9 48.8 213.2 45.5 352.1 51.6 69.9 64.6 15.9 250.0 46.7 35.9 126.8 180.0 65.4 0.0 0.0 29.7 0.1 31.5 70.5 1.1 312.6 400.8 56.7 18.6 39.5 0.0 0.0 56.9 568.9 2.0 0.1 0.0 0.0 10.2 0.0 0.0 0.0 0.6 3.9 27.0 0.0 0.2 283.9 2.2 235.2 10.7 29.0 561.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.5 0.3 0.2 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.1 11.8 1.3 0.0 120.0 249.5 2.3 1.0 1.5 0.9 0.1 0.0 0.1 0.3 114.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 57.6 51.2 91.5 56.1 48.7 50.6 50.8 53.2 45.5 64.6 65.4 30.5 3.2 5.6 5.9 0.6 104.1 1.3 7.3 5.7 0.2 1.2 5.6 16.1 4.3 2.5 9.2 0.0 15.5 0.7 0.0 1.9 2.7 1.8 1.4 28.3 45.2 0.0 5.3 0.1 0.2 50.0 180.0 7.7 1.1 3.8 8.4 223.5 1.6 4.4 3.3 0.1 0.0 0.0 4.0 43.6 13.5 147.9 3.0 35.6 25.3 2.0 0.1 0.0 20.6 0.0 1.2 0.0 782.7 0.0 3.0 0.0 0.8 1.6 0.2 1485.7 3.1 401.3 0.8 1.2 1.8 54.1 56.9 3.0 7.7 0.0 1.6 BMP1 "BMP-1, PCOLC" ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22165140-22212326 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 69.3;Endometrial stromal cells: 52.8;Smooth muscle cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" NA NA 9200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 11.7 17.4 3.8 6.3 4.6 1.4 9.0 4.7 4.4 15.6 4.9 8.1 4.8 12.7 3.9 7.0 11.8 9.8 5.9 4.3 3.9 7.7 14.7 8.3 1.7 5.0 4.1 5.9 4.4 3.4 3.4 27.3 4.1 9.6 5.3 0.6 3.7 6.1 3.4 6.2 5.9 14.4 4.3 5.0 4.3 2.4 4.2 1.5 10.0 3.1 1.8 10.4 10.3 4.4 15.2 20.4 7.4 30.2 47.8 41.8 23.2 54.1 50.1 33.8 27.6 5.1 27.4 3.7 32.0 56.9 18.9 51.2 5.1 27.8 6.5 3.6 6.9 6.7 24.5 7.9 31.7 2.9 14.3 49.8 26.5 25.2 11.4 78.3 31.4 5.2 7.1 10.6 19.6 4.6 1.4 3.0 4.7 17.0 8.3 6.4 8.2 15.2 26.7 4.1 2.8 10.6 52.5 3.1 13.4 20.4 5.0 8.3 41.4 17.0 18.4 32.3 23.9 4.0 2.2 0.6 23.8 10.1 28.0 0.0 0.4 0.0 0.6 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.2 0.0 0.1 3.8 4.6 4.7 4.4 4.3 3.9 5.0 4.1 4.1 4.3 4.2 4.4 12.5 6.4 69.3 5.5 0.8 6.2 5.2 22.6 4.0 2.6 5.0 6.1 4.9 2.8 6.7 5.5 0.0 3.3 3.2 31.9 0.0 25.1 0.7 3.1 52.8 14.1 3.0 0.8 3.5 8.2 9.5 28.7 1.1 5.7 15.2 13.9 14.6 20.1 4.3 1.7 2.7 6.2 0.0 3.4 6.1 1.1 10.2 5.4 10.6 4.7 1.0 2.2 3.1 6.6 6.7 15.3 18.6 10.9 2.8 4.7 13.2 4.1 2.2 1.1 26.3 6.4 43.7 1.5 4.0 6.5 5.3 24.4 3.3 34.2 10.7 8.0 BMP10 ENSG00000163217 "Bone morphogenetic protein 10" O95393 2 68860909-68871397 "Predicted secreted proteins" "Cell adhesion" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "heart muscle: 447.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "JURKAT: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 230000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.74e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 447.8 0.0 0.0 0.0 6.6 0.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BMP15 GDF9B ENSG00000130385 "Bone morphogenetic protein 15" O95972 X 50910735-50916641 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant, Premature ovarian failure" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 23: Spermatids - Flagellum & Golgi organization" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal keratinocytes: 167.1;Distal enterocytes: 125.6;Suprabasal keratinocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 31.6;HeLa: 19.6;hTERT-HME1: 17.8;RT4: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" NA NA 24400 21000 "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" 18.6 1.6 1.2 4.0 1.5 1.6 6.0 1.3 1.6 5.2 0.9 15.1 6.6 5.2 0.6 5.5 3.8 16.1 4.0 1.8 1.4 3.9 5.8 18.8 1.9 1.9 2.2 2.8 9.2 3.2 2.3 11.5 2.1 1.9 13.6 1.3 2.1 1.2 2.2 10.6 9.7 2.6 1.5 12.4 20.7 0.5 2.1 0.4 18.9 2.7 1.8 17.2 6.4 2.2 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.8 3.4 0.0 0.0 31.6 0.1 0.0 0.5 1.1 0.0 10.5 6.2 2.7 0.0 0.0 5.5 0.0 19.6 0.1 1.5 0.0 0.8 0.2 9.2 0.0 17.8 4.0 6.3 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.8 3.7 0.8 6.2 0.1 0.4 2.3 25.0 1.1 1.6 7.3 0.0 0.0 5.5 0.0 6.5 1.5 1.8 2.7 0.0 0.9 0.3 0.9 0.0 3.0 1.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 1.5 1.3 1.6 1.8 1.4 1.9 2.2 2.1 1.5 2.1 2.2 9.4 80.1 155.9 0.3 1.1 167.1 45.1 11.0 70.0 0.4 1.4 2.2 4.7 42.9 10.5 1.8 0.0 0.1 3.8 125.6 0.0 23.3 0.3 1.7 34.8 24.1 11.3 0.0 1.1 9.8 0.2 20.2 33.6 3.0 8.8 1.9 41.4 3.4 3.6 0.0 3.5 23.8 0.0 2.9 16.8 0.2 5.9 2.9 8.8 2.8 0.6 6.2 0.0 8.5 1.4 33.5 60.3 0.0 1.3 47.5 28.3 2.1 0.8 0.2 19.7 36.5 48.8 0.0 0.3 43.1 119.3 0.1 2.1 4.3 48.2 43.3 BMP3 ENSG00000152785 "Bone morphogenetic protein 3" P12645 4 81030708-81057627 "Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.3;lung: 5.5;urinary bladder: 9.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 32.2;Distal enterocytes: 68.9;Granulosa cells: 104.0;Paneth cells: 32.8;Proximal enterocytes: 25.2" "Group enriched" "Detected in some" 4 "lung cancer: 4.2;urothelial cancer: 7.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 10.3;Daudi: 16.3;RT4: 13.5;SK-BR-3: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.21e-3)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (3.36e-2)" "unprognostic (2.73e-3)" "unprognostic (9.11e-2)" "unprognostic (2.35e-1)" "unprognostic (1.94e-1)" "unprognostic (1.16e-4)" "unprognostic (2.26e-2)" "unprognostic (3.86e-1)" "unprognostic (1.11e-1)" "unprognostic (4.22e-2)" 1.5 0.4 0.3 0.3 0.2 0.8 1.2 0.2 0.3 0.4 0.1 9.3 3.2 0.0 0.1 0.0 0.9 2.0 0.0 0.1 0.6 0.1 0.0 5.5 0.3 0.7 0.7 2.5 0.0 0.0 0.0 0.0 0.5 0.2 6.8 0.5 1.3 0.0 0.0 0.3 7.2 0.5 0.6 0.0 1.1 0.1 1.4 0.0 0.0 0.6 1.5 9.5 0.2 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 0.0 0.0 0.0 1.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 13.5 0.1 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.3 0.1 0.6 0.7 0.7 0.5 0.6 1.4 0.0 0.0 3.2 32.2 0.0 0.2 0.1 0.5 0.7 0.0 2.2 0.1 0.0 1.3 0.0 15.1 0.0 0.0 0.0 0.0 68.9 0.0 0.0 0.0 0.9 0.1 0.3 0.0 0.0 1.6 0.0 0.0 2.1 0.0 0.0 0.0 104.0 0.0 0.0 0.0 0.0 5.6 5.0 6.1 0.0 1.2 0.0 0.9 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.2 32.8 0.0 0.0 0.5 25.2 0.1 9.4 0.1 0.0 0.3 1.2 0.2 0.3 0.0 0.4 0.0 0.0 0.1 14.1 3.8 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BMP5 ENSG00000112175 "Bone morphogenetic protein 5" P22003 6 55753653-55875590 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 71.3" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 17.7;Fibroblasts: 28.9;Microglial cells: 26.2;Smooth muscle cells: 26.3" "Cancer enhanced" "Detected in many" "lung cancer: 2.8" "Group enriched" "Detected in some" 4 "medulla oblongata: 2.3;pons: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 27.6;U-2 OS: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.84e-4)" "unprognostic (9.07e-4)" "unprognostic (3.50e-1)" "unprognostic (1.27e-1)" "unprognostic (6.21e-2)" "unprognostic (1.58e-1)" "unprognostic (2.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (6.76e-2)" "unprognostic (4.43e-3)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-2)" 1.5 1.0 0.1 1.0 0.3 0.2 1.0 0.6 0.5 0.0 2.0 6.2 8.3 0.0 0.0 0.9 0.0 2.3 3.8 0.1 0.0 2.4 3.2 12.9 0.4 2.3 0.3 0.0 1.6 1.1 3.5 71.3 2.9 14.1 7.4 0.0 1.2 0.0 4.4 0.1 9.7 0.3 0.1 0.0 3.3 0.0 0.1 0.2 1.0 12.3 0.2 9.3 0.3 0.0 0.0 0.0 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.5 0.1 0.0 2.3 0.3 2.9 0.1 0.1 0.0 1.8 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 1.0 17.7 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 2.7 0.4 0.0 0.8 28.9 0.0 0.0 0.0 0.0 2.2 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 26.2 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.6 26.3 0.0 0.1 0.3 0.0 1.9 0.6 0.0 0.0 0.1 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BMP7 OP-1 ENSG00000101144 "Bone morphogenetic protein 7" P18075 20 57168753-57266641 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;choroid plexus: 43.8;thyroid gland: 45.9" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Basal squamous epithelial cells: 51.8;Cytotrophoblasts: 137.4;Oligodendrocyte precursor cells: 74.4;Squamous epithelial cells: 44.2;Syncytiotrophoblasts: 56.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 172.1;MCF7: 202.3;OE19: 94.4;RPMI-8226: 77.8;SK-BR-3: 128.4;U-698: 237.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057757 Approved Nucleoplasm,Nucleoli,Vesicles "Secreted to blood" NA NA 248000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA057757: AB_2683518" "unprognostic (1.67e-1)" "unprognostic (9.72e-3)" "unprognostic (9.67e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.62e-1)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (4.63e-3)" "unprognostic (4.03e-2)" "unprognostic (1.09e-2)" "unprognostic (3.82e-2)" "unprognostic (4.30e-2)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (1.59e-1)" 1.5 6.5 33.1 1.9 34.6 0.0 1.3 37.2 27.9 8.5 43.8 2.9 2.2 1.2 17.2 23.9 9.5 0.4 13.8 35.6 28.5 6.3 0.0 1.6 1.0 36.2 36.3 0.2 0.5 0.0 2.7 25.7 34.7 5.9 1.7 5.3 3.9 9.2 0.3 22.5 1.9 0.3 32.8 0.6 3.6 0.7 39.7 3.8 45.9 0.0 2.1 6.8 13.0 42.8 0.3 0.7 23.4 5.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 20.0 6.8 172.1 41.3 0.0 8.7 48.3 5.2 0.0 0.0 0.4 17.2 0.1 0.0 0.0 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 202.3 0.0 0.1 12.3 94.4 0.0 0.1 0.1 77.8 0.0 0.2 0.4 17.8 5.5 128.4 0.5 15.2 0.9 0.4 0.4 0.1 10.9 0.0 0.1 0.2 0.3 237.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 34.6 37.2 27.9 35.6 28.5 36.2 36.3 34.7 32.8 39.7 42.8 0.6 6.4 2.2 74.1 0.4 13.8 13.4 12.9 51.8 4.7 0.9 4.6 15.1 0.0 4.2 1.8 0.0 137.4 0.1 0.2 0.0 0.0 5.3 1.7 2.4 1.2 2.4 0.0 0.9 0.0 21.0 13.5 2.0 2.5 21.6 0.1 0.0 0.0 11.0 1.7 4.7 1.5 6.1 0.0 1.9 4.9 0.3 0.4 3.6 2.8 0.1 38.4 0.0 74.4 8.7 0.0 0.3 0.4 2.5 6.6 0.2 2.2 1.9 2.4 0.0 1.3 0.8 1.8 3.4 44.2 9.7 56.9 0.9 0.7 1.5 18.1 BMP8A OP-2 ENSG00000183682 "Bone morphogenetic protein 8a" Q7Z5Y6 1 39491636-39529869 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 10 "thyroid gland: 91.6" "Group enriched" "Detected in some" 7 "Early spermatids: 42.2;Late spermatids: 164.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 7.0;HL-60: 5.8;U-2197: 22.2;U-266/70: 8.6;U-266/84: 7.9" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA047254: " "unprognostic (9.62e-3)" "unprognostic (2.11e-2)" "unprognostic (7.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.91e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (2.95e-9)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" 0.5 0.8 2.1 1.4 3.7 1.3 0.2 2.7 3.7 2.3 0.0 1.0 1.4 3.3 3.8 0.5 3.4 1.2 1.1 2.7 1.6 0.9 0.3 0.4 1.8 7.0 3.5 2.9 2.6 0.8 0.5 0.4 4.7 1.2 0.6 1.8 1.2 3.5 2.6 1.7 2.1 5.1 4.1 1.6 0.9 3.3 3.2 5.8 91.6 0.1 0.5 0.9 0.5 9.4 0.4 1.1 0.8 0.5 0.1 0.1 0.6 0.2 0.0 0.0 0.0 1.2 0.2 0.3 0.1 0.1 0.1 1.0 0.0 0.0 0.0 0.8 1.0 0.1 2.0 0.1 7.0 5.8 0.2 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.3 3.7 0.0 1.6 0.2 1.2 2.0 0.2 0.1 0.8 0.1 3.2 0.0 0.3 1.2 0.2 0.3 0.3 0.5 1.0 1.0 1.1 0.2 0.1 0.8 22.2 0.1 8.6 7.9 0.5 0.2 0.7 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 2.1 3.7 2.7 3.7 2.7 1.6 7.0 3.5 4.7 4.1 3.2 9.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.2 0.0 0.2 0.1 0.0 0.0 5.7 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 164.4 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 BMP8B "BMP8, OP-2" ENSG00000116985 "Bone morphogenetic protein 8b" P34820 1 39757182-39788865 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.4" "Group enriched" "Detected in many" 5 "Early spermatids: 72.1;Late spermatids: 106.5;Plasma cells: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 120.5;U-266/70: 33.7;U-266/84: 52.5;WM-115: 56.7" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047254: " "unprognostic (1.53e-3)" "unprognostic (7.29e-2)" "unprognostic (2.18e-1)" "unprognostic (6.64e-3)" "unprognostic (8.79e-2)" "unprognostic (3.44e-2)" "unprognostic (7.27e-2)" "unprognostic (7.56e-2)" "unprognostic (1.88e-1)" "unprognostic (7.41e-2)" "unprognostic (2.68e-1)" "unprognostic (4.72e-4)" "unprognostic (1.79e-2)" "unprognostic (3.15e-1)" "unprognostic (9.67e-2)" "unprognostic (8.68e-3)" "unprognostic (4.82e-1)" 1.7 5.6 2.1 1.5 2.0 0.8 0.9 1.1 5.3 2.1 0.1 3.8 5.4 1.5 3.3 1.0 1.3 0.8 1.0 2.8 1.8 0.9 0.6 1.3 0.7 13.4 3.5 0.8 7.0 1.8 2.7 1.5 3.3 2.4 2.7 0.5 1.7 2.5 0.6 2.0 4.1 0.7 2.8 1.5 1.8 2.2 2.6 0.4 4.7 1.6 0.7 1.6 2.1 4.7 2.7 4.5 0.3 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.8 5.4 0.1 1.8 0.0 0.7 0.4 4.2 0.0 0.0 1.0 5.8 4.9 3.6 0.3 0.1 0.6 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.6 18.1 0.2 3.7 0.1 2.5 0.3 2.8 1.8 2.7 15.9 5.7 4.0 2.7 13.0 3.4 4.3 0.3 13.4 0.9 3.1 120.5 0.0 0.1 0.3 1.1 0.2 33.7 52.5 2.0 0.0 3.7 56.7 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 2.1 2.0 1.1 5.3 2.8 1.8 13.4 3.5 3.3 2.8 2.6 4.7 0.0 0.0 1.8 0.0 3.5 0.4 0.6 0.2 0.0 0.5 1.1 0.8 1.2 0.0 0.8 0.0 0.0 0.0 0.9 13.5 0.0 1.0 72.1 1.1 0.6 0.4 1.2 0.0 0.4 3.4 0.0 1.7 1.1 2.3 0.0 0.3 0.4 0.0 0.4 0.0 0.3 2.0 0.0 0.0 2.7 106.5 1.2 0.8 5.4 0.0 0.7 0.1 0.0 8.0 1.8 2.2 2.2 0.7 38.9 0.4 5.0 0.0 0.4 0.5 0.0 1.8 3.4 0.8 0.4 0.4 0.0 0.0 0.7 0.1 1.2 0.8 BMPER "CRIM3, Cv2" ENSG00000164619 "BMP binding endothelial regulator" Q8N8U9 7 33904308-34156427 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Excitatory neurons: 286.9;Hepatic stellate cells: 117.8;Inhibitory neurons: 90.1;Oligodendrocyte precursor cells: 105.1" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.5;fHDF/TERT166: 17.0;HBF TERT88: 17.2;HSkMC: 15.5;hTEC/SVTERT24-B: 14.9;U-138 MG: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.50e-2)" "unprognostic (2.68e-1)" "unprognostic (2.83e-2)" "unprognostic (3.19e-2)" "unprognostic (1.93e-1)" "unprognostic (1.96e-4)" "unprognostic (5.34e-3)" "unprognostic (3.10e-1)" "unprognostic (9.98e-3)" "unprognostic (3.50e-3)" "unprognostic (8.01e-4)" "unprognostic (1.96e-1)" "unprognostic (5.67e-5)" "unprognostic (2.54e-1)" "unprognostic (2.62e-1)" "unprognostic (2.06e-2)" "unprognostic (3.47e-3)" 3.1 0.5 0.7 3.9 0.9 0.0 1.8 1.4 1.5 3.8 0.0 1.2 0.6 1.6 2.2 0.6 1.3 0.8 1.5 0.9 0.3 0.2 5.1 5.1 0.5 0.6 0.4 2.1 0.1 0.1 1.7 5.5 0.9 3.5 0.8 0.3 0.8 0.2 1.8 0.2 2.3 1.0 0.5 0.2 4.0 0.4 0.3 0.3 0.4 3.7 0.0 1.5 1.4 0.8 0.0 0.6 0.0 0.0 14.5 7.9 0.0 10.8 4.1 8.1 6.9 0.0 0.0 0.0 0.0 17.0 4.1 6.3 0.0 0.0 17.2 0.0 0.4 0.0 0.0 0.0 1.6 0.0 0.0 15.5 0.0 14.9 0.1 0.8 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 2.1 0.8 0.0 0.0 22.5 1.1 9.2 0.0 0.7 0.0 0.0 8.4 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 1.4 1.5 0.9 0.3 0.6 0.4 0.9 0.5 0.3 0.8 1.1 0.0 0.0 29.0 0.2 0.0 0.6 0.3 0.0 0.4 0.2 0.0 4.6 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 0.1 1.9 0.2 3.2 1.3 4.2 2.7 286.9 0.0 0.5 14.3 0.0 0.4 0.0 1.5 117.8 0.3 0.1 0.0 90.1 0.1 0.0 2.8 0.0 1.0 0.0 0.3 0.0 18.7 0.0 0.2 0.0 105.1 9.8 0.0 0.0 1.2 0.0 1.1 0.0 0.0 0.0 0.5 0.0 5.0 2.1 1.3 5.8 0.1 0.1 0.1 0.2 0.3 0.1 0.3 BPI BPIFD1 ENSG00000101425 "Bactericidal permeability increasing protein" P17213 20 38304150-38337505 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "bone marrow: 1503.7" "Group enriched" "Detected in some" 8 "Early spermatids: 201.8;Late spermatids: 220.6;Proximal tubular cells: 99.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 14.5;neutrophil: 7.1" "Group enriched" "Detected in many" 17 "granulocytes: 7.1;monocytes: 14.5" "Cell line enhanced" "Detected in single" "HL-60: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA061284 Enhanced "Secreted to blood" NA NA 7290000 78000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA061284: AB_2684465" "unprognostic (9.30e-4)" "unprognostic (5.49e-2)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (1.56e-1)" "unprognostic (4.50e-2)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-1)" "unprognostic (8.83e-6)" "unprognostic (2.66e-4)" "unprognostic (9.29e-2)" "unprognostic (2.32e-2)" "unprognostic (9.47e-3)" 0.5 0.2 0.1 0.1 0.2 1503.7 0.6 0.1 0.4 2.6 0.2 0.2 0.0 0.7 1.0 0.1 0.4 0.5 0.5 0.1 0.2 3.4 0.8 3.7 0.3 0.2 0.2 1.7 0.0 0.0 0.6 0.5 0.2 0.4 0.0 0.0 1.4 1.2 0.1 1.8 0.1 0.2 0.2 13.0 0.1 17.1 0.2 3.7 0.2 0.2 0.2 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 14.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.1 0.0 0.6 0.0 0.0 9.8 0.1 0.2 0.1 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.0 0.0 1.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.3 0.3 0.4 0.0 0.4 3.7 0.0 0.0 0.0 0.0 9.8 0.0 201.8 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.7 20.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 220.6 17.7 1.3 1.8 0.0 7.1 0.0 1.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 99.7 0.3 0.0 0.0 0.2 0.4 2.1 1.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 BPIFA1 "bA49G10.5, LUNX, PLUNC, SPLUNC1" ENSG00000198183 "BPI fold containing family A member 1" Q9NP55 20 33235995-33243311 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 6.2;lung: 18.3;pituitary gland: 12.1" "Cell type enriched" "Detected in some" 6 "Club cells: 1205.8" "Cancer enriched" "Detected in many" 27 "lung cancer: 262.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "cerebellum: 2.0" "Not detected" "Not detected" CAB025669 Supported "Secreted in other tissues" NA NA 1200000 "Cluster 19: Lung - Lung function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025669: " "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (3.65e-1)" "unprognostic (1.80e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 0.0 0.0 129.5 0.0 0.0 0.0 0.0 0.0 0.0 1205.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 126.1 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.0 0.0 0.0 0.0 80.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 BPIFA2 "bA49G10.1, C20orf70, PSP, SPLUNC2" ENSG00000131050 "BPI fold containing family A member 2" Q96DR5 20 33161768-33181412 "Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1619 "salivary gland: 6860.0" "Cell type enriched" "Detected in some" 4 "Ionocytes: 649.0" "Group enriched" "Detected in some" 4 "lung cancer: 2.6;pancreatic cancer: 2.9;stomach cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.0;RT4: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA044006 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA044006: AB_10963580" "unprognostic (9.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (3.03e-2)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.04e-1)" "unprognostic (6.14e-4)" 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6860.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 49.3 0.0 0.0 0.0 0.0 0.2 0.0 145.2 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 649.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 17.3 0.0 0.0 0.0 8.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 BPIFA3 "bA49G10.4, C20orf71, SPLUNC3" ENSG00000131059 "BPI fold containing family A member 3" Q9BQP9 20 33217310-33227806 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 537 "testis: 53.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 3057.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062708 Enhanced "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA062708: AB_2684843" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 736.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3057.9 14.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 18.2 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BPIFB1 "bA49G10.6, C20orf114, dJ1187J4.1, LPLUNC1, MGC14597, VEMSGP" ENSG00000125999 "BPI fold containing family B member 1" Q8TDL5 20 33273480-33309871 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 566.8;salivary gland: 271.3;stomach 1: 512.5" "Cell type enriched" "Detected in many" 5 "Club cells: 5748.4" "Cancer enhanced" "Detected in many" "stomach cancer: 75.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;OE19: 3.8;RT4: 2.2;SK-BR-3: 4.3" "Region enriched" "Detected in single" 6 "olfactory bulb: 4.8" "Low region specificity" "Detected in many" HPA024256 Enhanced "Secreted in other tissues" NA NA 2700000 "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA024256: AB_1845664" "unprognostic (2.42e-1)" "unprognostic (5.41e-2)" "unprognostic (3.67e-2)" "unprognostic (3.09e-1)" "unprognostic (6.72e-2)" "unprognostic (3.43e-2)" "unprognostic (9.37e-3)" "unprognostic (1.14e-1)" "unprognostic (2.82e-1)" "unprognostic (4.00e-2)" "unprognostic (9.01e-2)" "unprognostic (1.36e-7)" "unprognostic (3.30e-1)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" 0.1 0.1 0.0 0.0 0.3 0.0 0.9 0.0 0.1 566.8 0.0 0.5 25.6 0.0 0.0 47.1 0.1 3.4 0.0 0.4 0.0 0.0 0.1 112.5 0.2 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 1.2 0.0 0.0 271.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 512.5 3.5 0.0 0.2 0.0 0.0 1.2 8.3 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 3.8 0.0 0.4 0.0 0.1 0.0 2.2 0.0 0.0 0.0 4.3 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 22.7 0.0 0.0 1.3 1.4 614.0 0.0 0.0 2.0 1.3 0.4 2.8 5748.4 0.0 0.0 0.2 0.0 0.0 0.0 0.3 63.6 0.4 0.1 1.1 0.0 0.0 0.2 0.2 0.1 3.0 31.1 0.6 3.8 0.0 0.4 0.1 0.2 0.0 0.1 0.0 1021.3 0.0 1.9 82.9 0.3 1.5 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.7 0.0 2.0 0.0 0.0 1027.4 0.0 0.0 0.4 305.5 5.8 0.8 11.6 0.4 0.1 1.0 0.0 0.0 95.9 BPIFB2 "BPIL1, C20orf184, dJ726C3.2, LPLUNC2" ENSG00000078898 "BPI fold containing family B member 2" Q8N4F0 20 33007704-33023703 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "salivary gland: 2294.3" "Group enriched" "Detected in some" 4 "Breast glandular cells: 6.1;Breast myoepithelial cells: 9.1;Early spermatids: 4.8;Late spermatids: 9.3;Prostatic glandular cells: 7.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 582 "Hep G2: 232.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049491, HPA060121" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 36000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA049491: AB_2680792, HPA060121: AB_2684207" "unprognostic (1.94e-1)" "prognostic favorable (1.97e-5)" "unprognostic (2.24e-4)" "unprognostic (9.48e-2)" "unprognostic (9.81e-2)" "unprognostic (2.02e-3)" "unprognostic (1.72e-2)" "unprognostic (2.71e-1)" "unprognostic (9.28e-2)" "unprognostic (5.35e-1)" "unprognostic (8.19e-2)" 0.4 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 99.8 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 1.8 0.0 0.0 2294.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.1 9.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 BPIFB3 "C20orf185, dJ726C3.4, LPLUNC3, RYA3" ENSG00000186190 "BPI fold containing family B member 3" P59826 20 33055424-33073628 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Late spermatids: 1.8" "Cancer enriched" "Detected in single" 7 "ovarian cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "HEL: 3.7;HMC-1: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045741 Uncertain "Secreted in other tissues" NA NA "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "HPA045741: AB_2679439" "unprognostic (4.33e-2)" "unprognostic (1.06e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BPIFB4 "C20orf186, dJ726C3.5, LPLUNC4" ENSG00000186191 "BPI fold containing family B member 4" P59827 20 33079644-33111751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "pituitary gland: 8.4" "Cell type enhanced" "Detected in single" "Basal respiratory cells: 2.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 2.3;U-2 OS: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA047388 Approved "Actin filaments,Cytosol" "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Actin filaments, Cytosol" "HPA047388: " "unprognostic (1.32e-1)" "unprognostic (1.16e-1)" "unprognostic (1.61e-1)" "unprognostic (2.75e-2)" "unprognostic (1.31e-3)" "unprognostic (4.70e-2)" "unprognostic (3.42e-2)" "unprognostic (2.03e-1)" "unprognostic (3.98e-4)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (8.97e-2)" 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 BPIFB6 "BPIL3, LPLUNC6" ENSG00000167104 "BPI fold containing family B member 6" Q8NFQ5 20 33031648-33044047 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "salivary gland: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043057 Uncertain "Secreted in other tissues" NA NA "Cluster 24: Salivary gland - Salivary secretion" "HPA043057: AB_10796683" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BPIFC "BPIL2, dJ149A16.7" ENSG00000184459 "BPI fold containing family C" Q8NFQ6 22 32413847-32464484 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 63.6" "Cell type enhanced" "Detected in some" "Early spermatids: 22.8;Late spermatids: 9.8;Suprabasal keratinocytes: 4.7" "Group enriched" "Detected in some" 11 "head and neck cancer: 1.6;melanoma: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 22 "basophil: 2.1" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.1" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.74e-1)" "unprognostic (3.48e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (2.58e-1)" "unprognostic (3.48e-2)" "unprognostic (2.74e-1)" "unprognostic (2.58e-1)" "unprognostic (2.76e-3)" "unprognostic (1.41e-2)" "unprognostic (2.80e-1)" 0.1 0.0 0.2 0.0 0.1 0.0 3.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 63.6 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 9.8 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 4.7 0.0 0.0 0.0 0.0 0.0 BRINP2 "DBCCR1L2, FAM5B" ENSG00000198797 "BMP/retinoic acid inducible neural specific 2" Q9C0B6 1 177170958-177282422 "Predicted secreted proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.6;brain: 19.9" "Group enriched" "Detected in some" 4 "Astrocytes: 121.1;Excitatory neurons: 116.8;Inhibitory neurons: 148.3;Oligodendrocyte precursor cells: 96.5" "Cancer enriched" "Detected in some" 5 "glioma: 11.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.7;PC-3: 1.3;REH: 2.1;SCLC-21H: 5.6;SH-SY5Y: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050681 Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA050681: " "unprognostic (7.78e-2)" "unprognostic (4.49e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.43e-2)" "unprognostic (1.77e-1)" "unprognostic (5.77e-2)" "unprognostic (1.23e-2)" "unprognostic (1.95e-2)" "unprognostic (2.20e-4)" "unprognostic (8.95e-2)" "unprognostic (1.78e-2)" "unprognostic (2.60e-3)" "unprognostic (1.17e-1)" "unprognostic (2.60e-2)" "unprognostic (4.82e-3)" 0.6 9.6 17.2 0.0 16.5 0.0 0.9 1.3 19.9 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.2 17.9 10.7 0.0 0.1 0.0 0.0 4.5 9.6 0.0 0.0 0.0 4.2 0.5 4.9 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 2.1 16.2 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 2.1 0.0 0.0 0.0 0.0 5.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 16.5 1.3 19.9 17.9 10.7 4.5 9.6 4.9 4.9 16.2 13.4 0.0 0.0 0.0 121.1 0.0 0.0 0.0 0.0 0.0 1.1 1.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.4 0.2 0.3 0.0 0.0 0.0 116.8 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.0 0.1 15.2 148.3 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 25.3 0.0 0.5 0.0 96.5 15.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 1.3 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 BRINP3 "DBCCR1L, DBCCR1L1, FAM5C" ENSG00000162670 "BMP/retinoic acid inducible neural specific 3" Q76B58 1 190097658-190478404 "Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1;intestine: 17.9" "Cell type enhanced" "Detected in some" "Astrocytes: 266.7;Excitatory neurons: 333.7;Inhibitory neurons: 129.7;Oligodendrocyte precursor cells: 1079.2" "Group enriched" "Detected in some" 14 "breast cancer: 3.4;glioma: 8.6;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054693 Uncertain "Secreted in other tissues" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054693: AB_2682575" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (8.25e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (9.84e-2)" "unprognostic (4.58e-3)" 0.3 1.7 19.8 0.6 16.8 0.0 1.4 18.7 19.2 0.2 0.0 6.6 4.6 0.2 3.0 1.7 0.4 1.6 5.3 27.1 25.8 2.3 0.0 1.2 0.0 12.5 15.7 0.0 0.0 0.0 0.2 0.0 12.4 6.8 6.7 0.7 1.6 5.1 0.1 0.1 17.9 0.6 13.1 0.0 0.2 3.4 26.0 0.1 2.1 0.0 0.1 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 16.8 18.7 19.2 27.1 25.8 12.5 15.7 12.4 13.1 26.0 10.4 0.0 0.0 0.0 266.7 0.0 0.0 0.1 0.0 0.0 0.7 0.3 0.4 2.3 0.0 0.0 3.7 0.0 0.0 0.0 2.0 3.9 0.0 63.3 0.0 0.0 0.1 1.2 0.0 333.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 129.7 2.8 0.0 0.0 0.0 10.5 0.0 0.1 0.0 8.4 0.0 0.0 0.0 1079.2 4.3 0.0 10.8 0.0 0.0 1.0 8.1 0.3 0.0 0.1 0.0 0.0 5.8 2.0 0.7 0.1 0.0 0.0 0.0 0.0 5.2 0.1 BSPH1 "BSP1, ELSPBP2" ENSG00000188334 "Binder of sperm protein homolog 1" Q075Z2 19 47968046-47992170 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "epididymis: 383.0" "Cell type enhanced" "Detected in single" "Bipolar cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA048335 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA048335: AB_2732546" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 383.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BTBD17 "BTBD17A, LGALS3BPL, TANGO10A" ENSG00000204347 "BTB domain containing 17" A6NE02 17 74356416-74361868 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "brain: 7.1" "Cell type enriched" "Detected in some" 6 "Horizontal cells: 28.6" "Cancer enriched" "Detected in some" 5 "glioma: 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "AF22: 2.9;NTERA-2: 3.8;SCLC-21H: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA025022 Approved "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA025022: AB_2067352" "unprognostic (2.63e-1)" "unprognostic (2.77e-1)" "unprognostic (4.82e-5)" "unprognostic (3.89e-2)" "unprognostic (2.55e-1)" "unprognostic (9.89e-3)" 0.0 0.5 2.8 0.0 2.7 0.0 0.0 1.7 3.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 0.0 0.0 0.0 2.5 3.5 0.0 0.2 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.4 0.3 7.1 0.0 0.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 1.7 3.3 2.3 5.7 2.5 3.5 2.8 2.5 7.1 2.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 4.2 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 0.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.5 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 BTC ENSG00000174808 Betacellulin P35070 4 74744759-74794523 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.5;Respiratory ciliated cells: 43.1;Skeletal myocytes: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.1;MCF7: 5.8;RPTEC TERT1: 9.5;SK-BR-3: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 314000 "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (7.36e-2)" "unprognostic (4.99e-2)" "unprognostic (7.04e-2)" "unprognostic (7.76e-3)" "unprognostic (3.87e-3)" "unprognostic (1.01e-3)" "unprognostic (1.05e-1)" "unprognostic (7.17e-3)" "unprognostic (2.68e-2)" "unprognostic (8.81e-2)" "unprognostic (1.50e-2)" "unprognostic (5.35e-1)" "prognostic favorable (6.10e-5)" "unprognostic (2.33e-1)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (2.31e-3)" 2.5 1.7 0.6 1.8 0.8 0.0 4.1 0.2 0.9 2.7 3.9 25.6 4.3 3.2 6.9 11.0 7.6 6.2 0.4 0.9 0.7 4.4 1.1 4.6 0.1 1.0 1.3 0.9 2.9 7.3 1.6 0.4 0.8 4.6 7.4 4.2 6.9 4.4 0.4 13.7 6.8 10.0 0.9 0.1 6.2 0.6 0.7 0.2 5.8 1.0 0.5 4.6 1.9 0.7 3.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.1 0.0 16.1 0.0 3.3 0.0 2.3 0.5 0.0 0.1 0.0 0.0 0.3 0.1 0.6 0.0 0.2 0.0 0.0 0.0 1.2 0.3 0.1 2.6 0.1 0.0 0.0 0.1 0.4 5.8 0.1 0.0 0.0 1.7 2.4 0.0 0.0 0.0 9.5 4.6 0.2 0.0 2.4 6.4 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.3 2.8 0.3 0.0 0.0 2.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.8 0.2 0.9 0.9 0.7 1.0 1.3 0.8 0.9 0.7 0.7 2.9 9.6 10.8 0.0 0.0 0.6 3.9 3.7 0.0 2.4 3.9 1.4 0.9 4.3 12.2 11.0 2.1 0.5 0.0 6.1 0.0 4.1 2.0 18.5 1.3 0.7 12.0 0.0 7.7 5.9 0.0 0.7 8.6 10.7 0.0 6.7 2.9 0.4 0.1 0.0 3.2 9.9 10.2 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 10.4 0.0 2.5 0.3 3.3 4.9 0.0 0.0 4.3 1.7 1.1 43.1 5.7 0.0 18.5 5.6 0.0 0.2 8.4 3.0 0.3 0.2 1.2 7.3 7.6 BTD ENSG00000169814 Biotinidase P43251 3 15601341-15722311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 95.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" NA NA 2800000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA052275: AB_2681782" "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" 25.3 16.7 10.7 8.0 12.7 13.1 16.4 20.2 12.6 13.7 11.0 15.9 46.1 13.2 62.4 9.9 18.3 19.9 10.2 11.5 10.3 37.6 95.9 15.9 9.6 12.0 10.0 25.3 44.1 27.7 5.9 17.0 12.6 19.5 17.0 35.2 16.0 21.1 7.8 9.5 30.7 14.1 10.3 11.3 24.4 18.2 9.9 10.6 26.8 11.4 10.4 14.3 7.5 19.1 9.2 22.0 7.8 7.3 51.7 15.3 39.6 15.4 18.4 16.2 28.3 10.1 21.5 4.1 16.3 31.6 7.1 9.7 5.3 16.7 18.7 7.6 11.7 12.9 28.8 24.8 12.7 8.8 14.7 18.3 16.9 42.9 5.1 39.7 30.5 5.9 8.7 32.3 44.7 11.1 4.5 8.2 8.5 16.9 13.0 5.9 18.4 27.9 16.5 17.7 5.3 11.8 17.9 5.2 24.4 15.1 19.9 11.3 24.3 20.5 13.6 19.1 10.1 8.9 11.4 4.1 21.4 7.7 14.4 74.1 20.7 44.9 22.9 19.6 21.0 14.7 23.3 19.2 21.4 13.1 19.7 15.4 19.8 15.0 15.8 24.9 28.8 16.5 10.7 12.7 20.2 12.6 11.5 10.3 12.0 10.0 12.6 10.3 9.9 19.1 14.9 6.4 11.0 11.8 11.7 5.9 12.4 25.0 6.2 13.5 9.1 7.9 6.0 45.8 16.7 18.4 18.8 25.3 19.7 9.9 5.9 21.1 31.0 9.5 6.0 9.1 7.2 4.0 6.6 28.5 22.4 14.5 9.7 5.7 5.1 8.9 20.3 63.3 14.9 5.0 12.2 8.5 16.2 8.2 5.9 17.9 32.3 9.2 10.6 5.6 8.7 19.2 6.2 27.2 23.9 12.0 17.9 18.0 16.6 6.3 52.1 32.0 19.8 54.1 13.1 8.5 8.6 45.3 7.5 7.7 5.5 23.1 13.6 17.4 8.9 9.5 C10orf95 FLJ14280 ENSG00000120055 "Chromosome 10 open reading frame 95" 10 102449837-102451543 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 9.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 30.1;Rod photoreceptor cells: 18.4;Syncytiotrophoblasts: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 11.8;JURKAT: 11.7" "Low region specificity" "Detected in single" "Secreted - unknown location" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.31e-1)" "unprognostic (7.76e-3)" "unprognostic (3.19e-1)" "unprognostic (5.62e-3)" "unprognostic (4.02e-1)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (5.98e-2)" "unprognostic (1.50e-2)" "unprognostic (1.01e-1)" "unprognostic (4.42e-2)" "unprognostic (2.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.22e-2)" "unprognostic (4.80e-3)" 0.5 1.5 0.7 1.8 0.6 2.0 0.2 2.8 1.1 1.1 0.9 1.2 2.5 1.2 0.4 1.3 9.7 1.4 0.6 0.6 0.8 1.4 0.4 3.5 2.9 0.3 0.2 1.1 4.7 0.1 1.3 0.7 0.1 1.6 0.4 4.7 4.0 0.1 0.7 4.1 2.3 0.0 0.0 2.6 3.6 0.7 0.9 0.0 5.3 0.0 0.5 0.6 0.5 0.1 5.7 1.1 0.1 2.3 0.0 0.0 4.9 0.2 0.0 0.0 0.0 4.4 9.8 5.0 2.2 0.0 0.7 9.8 0.0 0.4 0.0 4.3 11.8 3.2 4.7 3.7 0.0 4.4 3.0 0.1 1.8 0.0 0.1 3.1 0.0 11.7 5.6 4.1 0.0 4.5 2.4 4.2 2.2 2.0 3.3 7.0 0.1 5.4 1.1 2.0 8.8 1.3 2.4 1.5 3.1 1.7 4.8 0.3 0.4 0.2 1.0 0.2 0.5 3.5 2.9 3.3 0.2 6.5 0.1 2.1 1.2 1.7 7.8 0.6 7.4 10.7 8.4 7.9 3.6 8.3 11.7 9.9 0.9 10.1 0.3 6.3 9.6 4.9 0.7 0.6 2.8 1.1 0.6 0.8 0.3 0.2 0.1 0.0 0.9 0.1 0.3 0.0 3.2 0.7 3.1 1.5 4.3 0.5 0.0 4.6 2.4 2.5 0.1 2.8 4.2 5.5 10.4 2.3 6.4 2.5 3.9 1.5 0.1 30.1 0.7 1.0 1.2 1.3 0.7 1.1 1.7 0.3 1.5 4.0 0.0 0.8 0.4 0.3 2.3 3.3 0.7 3.7 4.1 1.0 1.0 0.5 0.6 1.4 0.0 0.0 2.2 2.7 6.2 0.0 0.0 0.7 0.4 0.7 2.5 3.3 2.0 4.2 8.7 18.4 0.0 0.9 0.5 0.7 1.4 1.9 1.6 38.0 3.2 0.7 3.2 2.9 C10orf99 "AP-57, CSBF, FLJ21763, RLLV1833, UNQ1833" ENSG00000188373 "Chromosome 10 open reading frame 99" Q6UWK7 10 84173801-84185294 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 193.2;intestine: 274.9;vagina: 115.3" "Group enriched" "Detected in some" 11 "Distal enterocytes: 853.2;Intestinal goblet cells: 267.6;Paneth cells: 815.9;Proximal enterocytes: 364.8;Undifferentiated cells: 402.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 91.5;head and neck cancer: 102.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 52.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050920 Enhanced "Secreted in other tissues" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA050920: AB_2681274" "unprognostic (3.13e-2)" "unprognostic (1.43e-1)" "unprognostic (6.04e-2)" "unprognostic (1.78e-2)" "unprognostic (7.46e-3)" "unprognostic (2.05e-1)" "unprognostic (7.98e-2)" "unprognostic (2.04e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (3.70e-1)" "unprognostic (4.67e-2)" 0.4 0.0 0.0 16.8 0.0 0.0 0.5 0.0 0.0 46.7 0.0 268.5 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 274.9 0.1 21.7 2.6 0.0 38.5 21.5 13.1 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 17.4 33.5 115.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 6.8 1.2 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.1 853.2 0.0 0.0 0.4 3.3 0.8 0.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 4.5 0.0 0.0 0.0 0.0 0.0 0.0 267.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 815.9 0.0 0.0 1.0 364.8 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 46.0 2.3 0.0 1.4 0.0 402.8 46.4 C11orf45 "FLJ43646, MGC35558" ENSG00000174370 "Chromosome 11 open reading frame 45" Q8TAV5 11 128899565-128906035 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.7;Hofbauer cells: 8.7;Kupffer cells: 5.9;Late spermatids: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.2;U-937: 8.9" HPA039716 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA039716: AB_10672892" "unprognostic (8.32e-2)" "unprognostic (3.93e-2)" "unprognostic (5.99e-3)" "unprognostic (1.35e-3)" "unprognostic (1.01e-1)" "unprognostic (9.93e-2)" "unprognostic (4.50e-5)" "unprognostic (1.97e-2)" "unprognostic (4.78e-2)" "unprognostic (3.10e-1)" "unprognostic (2.80e-1)" "unprognostic (9.27e-2)" "unprognostic (2.55e-9)" "unprognostic (2.37e-1)" "unprognostic (2.60e-2)" "unprognostic (6.87e-2)" "unprognostic (7.22e-2)" 0.6 3.3 1.7 0.7 4.4 0.8 0.9 0.6 2.1 1.0 0.8 0.7 1.4 0.5 0.6 2.9 1.0 2.0 4.5 1.4 1.6 2.0 0.5 2.6 0.8 1.9 1.9 0.9 2.6 3.8 2.3 2.1 1.6 1.1 0.9 0.2 1.6 2.8 0.1 6.6 0.9 0.5 1.1 1.5 1.8 1.1 2.3 2.4 1.8 0.2 0.9 1.2 1.3 2.2 2.4 4.5 0.0 0.0 0.3 0.4 1.6 0.8 4.7 1.7 4.2 6.3 5.8 0.0 3.2 0.5 4.2 2.3 2.4 11.2 0.8 0.0 1.1 0.3 2.7 0.0 0.2 0.0 0.0 0.3 1.5 1.3 0.9 3.8 1.0 3.5 0.0 0.2 2.0 1.2 2.6 2.4 1.8 1.0 3.9 1.1 4.6 0.5 3.9 1.1 0.0 0.2 1.8 5.0 0.3 1.2 0.8 4.4 0.5 0.0 6.2 0.0 0.8 0.1 0.0 0.0 0.8 8.9 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.9 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.7 4.4 0.6 2.1 1.4 1.6 1.9 1.9 1.6 1.1 2.3 2.2 0.1 0.0 0.5 0.0 0.0 2.8 1.3 0.9 5.7 0.0 0.3 0.4 1.7 0.0 0.2 0.0 0.0 2.0 0.0 0.1 1.9 1.0 2.0 0.3 0.1 0.2 0.0 0.0 0.3 0.8 2.1 0.3 0.0 0.5 1.3 0.3 0.4 0.0 8.7 0.0 0.2 0.1 0.0 5.9 0.8 8.2 0.0 2.2 0.0 2.8 0.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 1.5 1.7 3.0 0.9 1.2 0.2 0.1 0.2 1.1 C11orf94 ENSG00000234776 "Chromosome 11 open reading frame 94" C9JXX5 11 45906513-45907272 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 148 "testis: 54.7" "Group enriched" "Detected in some" 82 "Early spermatids: 390.0;Late spermatids: 189.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.55e-1)" "unprognostic (2.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.36e-1)" "unprognostic (7.28e-2)" "unprognostic (5.99e-2)" "unprognostic (6.21e-3)" "unprognostic (1.97e-1)" "unprognostic (1.43e-1)" "unprognostic (7.11e-2)" "unprognostic (3.33e-2)" "unprognostic (4.24e-2)" "unprognostic (9.05e-4)" "unprognostic (1.90e-1)" "unprognostic (1.10e-1)" "unprognostic (3.28e-1)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 390.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 189.9 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.1 0.2 0.1 C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA002569: AB_1078334" "prognostic favorable (5.05e-4)" "unprognostic (1.31e-2)" "unprognostic (2.97e-2)" "unprognostic (2.23e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (4.86e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (7.11e-2)" 8.3 4.8 6.5 5.7 7.7 12.6 8.2 6.7 7.0 11.2 8.5 8.8 7.4 8.7 11.4 7.4 9.5 9.2 5.6 6.2 7.3 11.1 8.9 6.7 10.1 7.7 7.2 10.3 9.6 8.3 6.5 5.0 7.5 9.6 9.6 4.4 8.0 5.7 6.7 18.3 8.1 6.8 6.7 10.6 8.3 4.0 7.2 15.7 11.5 7.9 10.5 8.6 8.3 9.5 5.7 10.5 8.8 12.3 13.9 30.8 12.2 6.6 10.2 5.1 6.7 6.6 16.5 16.0 6.1 6.0 7.2 11.8 5.4 16.6 4.7 6.3 3.8 10.1 14.0 15.3 12.1 7.4 8.3 22.4 12.8 7.6 9.6 18.5 9.6 10.1 11.1 3.4 5.3 16.3 9.5 13.6 3.0 12.3 7.3 15.1 8.4 9.8 6.7 8.6 31.8 13.8 8.8 8.4 9.0 9.4 13.0 12.8 5.5 9.6 12.7 4.3 6.7 11.9 3.6 11.0 6.6 9.1 10.0 12.2 7.7 22.9 8.1 7.4 7.2 10.4 6.5 8.5 9.1 10.0 9.8 9.4 11.2 10.4 13.0 6.3 13.4 7.1 6.5 7.7 6.7 7.0 6.2 7.3 7.7 7.2 7.5 6.7 7.2 9.5 3.1 9.6 1.1 14.7 8.7 3.1 4.1 4.6 10.2 1.4 4.0 4.1 3.3 1.5 2.6 0.0 4.2 4.3 7.8 3.7 7.9 3.9 0.8 3.3 2.6 3.3 15.7 6.5 3.4 3.0 5.7 3.9 7.7 3.0 7.0 4.7 1.4 1.5 3.8 0.0 3.4 6.3 4.1 5.5 2.5 1.5 4.4 3.4 5.4 9.4 1.9 4.1 7.2 7.1 9.9 3.1 7.3 4.1 5.2 1.9 4.6 3.6 4.6 2.0 6.6 3.8 3.7 2.9 8.2 5.3 1.6 3.0 5.2 4.1 5.1 2.5 C15orf61 LOC145853 ENSG00000189227 "Chromosome 15 open reading frame 61" A6NNL5 15 67521131-67530146 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 23.7" "Cell type enhanced" "Detected in all" "Early spermatids: 222.6;Spermatocytes: 258.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062820 Approved Nucleoli,Vesicles,Cytosol "Secreted - unknown location" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Vesicles" Cytosol "HPA062820: AB_2684874" "unprognostic (1.35e-1)" "unprognostic (9.42e-3)" "unprognostic (2.11e-1)" "unprognostic (5.41e-2)" "unprognostic (2.40e-1)" "unprognostic (2.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.87e-3)" "unprognostic (8.95e-2)" "unprognostic (4.01e-2)" "unprognostic (1.04e-2)" "unprognostic (8.45e-2)" "prognostic favorable (5.31e-5)" "unprognostic (2.42e-2)" "unprognostic (9.78e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" 4.7 3.8 2.3 1.5 6.2 5.3 3.6 7.1 4.2 3.1 0.0 2.3 2.8 2.3 1.9 2.0 2.9 1.5 5.7 3.8 1.6 3.0 2.5 2.3 1.3 1.0 2.4 2.7 4.2 4.4 5.1 2.0 1.0 2.5 2.2 10.8 2.6 2.1 23.7 4.1 1.8 1.4 0.7 1.7 2.4 7.7 2.1 1.4 2.8 8.3 1.0 2.2 2.4 2.3 4.2 4.4 1.1 4.9 5.0 7.2 3.1 1.8 3.2 3.3 2.6 3.4 2.9 3.5 3.8 2.0 3.9 4.9 4.4 1.2 2.7 2.1 10.4 3.7 3.3 4.6 3.2 4.6 3.0 7.5 3.4 1.1 4.0 2.4 1.6 10.6 4.3 7.6 1.0 2.4 3.8 7.6 1.8 3.3 5.6 5.1 2.5 13.0 2.3 2.9 6.4 4.8 3.2 3.0 6.1 2.1 2.7 7.1 1.6 4.4 6.8 5.5 4.7 7.1 11.2 8.5 1.9 9.0 2.2 7.9 4.3 7.8 4.5 3.7 5.2 5.3 5.9 4.5 4.8 3.6 6.2 5.0 0.5 3.8 3.2 4.9 4.0 3.5 2.3 6.2 7.1 4.2 3.8 1.6 1.0 2.4 1.0 0.7 2.1 2.3 28.0 22.4 13.5 4.9 23.1 67.2 32.6 32.3 120.7 75.5 55.7 82.3 74.5 18.6 14.3 16.5 37.5 42.6 23.8 38.6 80.3 25.1 222.6 17.5 24.2 26.8 27.1 11.8 14.8 29.8 31.9 56.8 15.8 17.1 34.8 15.2 22.9 44.7 30.5 13.5 15.7 47.5 48.8 24.8 25.6 42.6 41.0 19.9 37.4 3.7 15.6 97.1 23.7 5.0 8.5 27.6 48.4 25.6 37.4 63.3 49.0 77.1 8.4 93.9 32.9 38.2 38.7 258.9 52.1 62.7 60.9 20.5 34.4 28.9 39.2 20.0 C16orf89 MGC45438 ENSG00000153446 "Chromosome 16 open reading frame 89" Q6UX73 16 5044122-5066110 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 108.3;thyroid gland: 228.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Alveolar cells type 2: 268.1;Club cells: 70.4;Distal tubular cells: 113.5;Fibroblasts: 43.8" "Group enriched" "Detected in many" 14 "lung cancer: 64.7;thyroid cancer: 145.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;Hep G2: 2.5;HHSteC: 1.3;NTERA-2: 1.7;U-2197: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013613, HPA016934" Enhanced "Secreted to blood" NA NA 1400000 "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA013613: AB_1845584, HPA016934: AB_2732417" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.97e-1)" "unprognostic (6.29e-2)" "unprognostic (3.79e-2)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (1.01e-2)" "unprognostic (9.23e-2)" "unprognostic (2.65e-1)" "unprognostic (6.39e-2)" "unprognostic (3.25e-2)" "unprognostic (6.64e-3)" "unprognostic (3.53e-2)" "unprognostic (1.25e-1)" "unprognostic (5.54e-2)" "unprognostic (8.48e-3)" 17.8 4.2 20.0 6.0 21.6 0.2 12.8 18.8 28.3 20.2 15.0 6.3 17.6 3.5 87.1 6.7 12.4 45.0 18.8 19.4 19.9 16.8 0.3 108.3 0.9 19.9 18.5 2.8 5.4 0.1 5.7 0.9 19.0 4.2 5.0 0.5 35.0 1.1 0.2 0.6 7.9 4.9 19.6 0.6 82.4 1.2 22.6 2.8 228.8 3.9 2.2 14.4 3.2 22.7 0.0 0.1 0.0 0.2 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.6 2.5 1.3 0.1 0.2 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.1 0.7 0.3 1.7 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.5 0.3 0.1 0.0 0.0 0.2 0.1 2.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.2 0.0 0.1 0.0 0.0 20.0 21.6 18.8 28.3 19.4 19.9 19.9 18.5 19.0 19.6 22.6 22.7 0.9 44.8 268.1 23.2 0.0 0.4 1.8 0.3 0.6 0.5 23.6 18.0 2.8 0.0 70.4 0.0 0.0 0.1 0.1 0.1 113.5 0.0 1.7 3.7 0.4 1.3 0.0 0.0 0.9 7.8 0.1 43.8 17.3 0.3 5.1 0.0 0.0 0.0 6.0 0.0 0.7 0.6 6.1 0.0 0.4 2.7 9.3 0.7 0.0 11.2 0.0 0.3 0.0 1.0 1.6 0.7 0.4 14.7 0.0 5.0 0.0 1.5 16.9 0.2 0.0 1.9 1.9 0.8 0.1 0.6 0.3 0.3 0.6 0.0 0.7 5.0 C17orf67 ENSG00000214226 "Chromosome 17 open reading frame 67" Q0P5P2 17 56791913-56838773 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 9.5;MOLT-4: 14.6;PC-3: 9.7" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.1" "Region enhanced" "Detected in many" "spinal cord: 15.6" HPA043479 Approved "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA043479: AB_10964083" "unprognostic (2.78e-2)" "unprognostic (5.24e-2)" "unprognostic (1.83e-1)" "unprognostic (3.54e-3)" "unprognostic (1.69e-3)" "unprognostic (1.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.47e-1)" "unprognostic (4.63e-2)" "unprognostic (2.82e-3)" "unprognostic (9.64e-2)" "unprognostic (2.99e-2)" "unprognostic (1.68e-5)" "unprognostic (2.49e-1)" "unprognostic (3.27e-1)" "unprognostic (2.20e-2)" "unprognostic (1.43e-3)" 1.3 0.4 2.7 1.3 2.2 0.5 1.0 2.2 4.3 1.9 1.8 1.3 0.7 1.8 1.4 0.8 1.5 1.7 0.9 2.1 3.2 0.8 2.2 1.6 1.5 2.3 2.5 1.8 1.7 0.5 1.3 0.8 2.5 1.7 0.5 0.8 0.9 1.2 0.6 0.5 1.6 1.2 1.9 2.6 1.0 1.8 3.1 5.5 1.3 0.9 1.0 1.4 1.7 3.3 3.2 2.0 1.3 1.4 0.6 0.9 0.6 1.8 2.3 1.5 1.7 2.6 1.1 1.7 3.1 0.8 1.7 1.6 0.9 0.5 1.5 9.5 3.4 1.6 2.4 1.6 0.8 1.2 3.1 0.3 2.4 1.0 1.0 1.1 1.5 3.3 1.6 7.9 1.0 2.5 14.6 2.2 1.2 1.0 9.7 3.1 2.5 1.8 1.1 0.8 0.7 1.6 1.8 0.4 1.0 0.5 2.0 0.9 2.2 1.6 4.0 1.1 1.3 3.2 8.7 0.9 1.1 1.4 0.6 0.0 0.1 0.3 0.2 0.2 0.3 1.5 0.6 0.8 0.1 0.8 0.6 0.8 0.2 0.2 0.3 0.3 1.5 0.3 2.7 2.2 2.2 4.3 2.1 3.2 2.3 2.5 2.5 1.9 3.1 3.3 15.3 3.2 0.0 2.9 8.4 2.3 16.3 0.5 4.6 12.4 3.9 5.6 1.8 11.5 0.1 7.3 14.6 0.1 8.4 12.1 0.0 3.3 9.0 3.3 6.3 13.5 8.9 3.6 7.2 1.4 0.8 4.8 3.1 6.8 1.3 3.1 7.9 9.0 2.9 5.0 10.6 4.6 0.0 8.1 4.7 7.4 7.8 5.0 1.8 15.9 3.8 2.7 12.3 6.6 6.2 2.2 11.9 1.2 4.3 12.4 4.1 0.4 1.0 20.1 0.0 2.4 5.1 12.9 9.5 2.2 1.7 0.3 11.0 4.3 6.3 7.2 C17orf99 "GLPG464, UNQ464" ENSG00000187997 "Chromosome 17 open reading frame 99" Q6UX52 17 78146353-78166177 "Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 9.0" "Cell type enriched" "Detected in some" 29 "Erythroid cells: 52.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "HaCaT: 3.5;HMC-1: 7.1;K-562: 4.2" "Not detected" "Not detected" HPA029655 Uncertain "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA029655: AB_10601691" "unprognostic (3.55e-5)" "unprognostic (1.87e-2)" "unprognostic (2.06e-1)" "unprognostic (1.22e-1)" "unprognostic (1.88e-1)" "unprognostic (1.45e-3)" "unprognostic (1.47e-3)" "unprognostic (2.39e-1)" "unprognostic (3.86e-1)" "unprognostic (9.77e-2)" "unprognostic (2.05e-2)" "unprognostic (5.13e-2)" "unprognostic (1.38e-4)" "unprognostic (6.58e-2)" "unprognostic (4.72e-2)" "unprognostic (2.66e-1)" "unprognostic (5.78e-3)" 0.0 0.0 0.0 0.1 0.0 9.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 1.8 0.4 0.6 1.1 0.1 0.3 0.5 0.0 0.7 1.8 0.0 0.2 0.1 0.6 0.0 0.1 0.0 0.1 0.2 0.5 0.0 52.6 0.3 0.4 0.4 0.4 0.0 0.3 0.0 0.1 0.4 0.2 0.5 0.0 0.3 0.7 0.0 0.0 0.7 0.1 0.6 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.7 0.2 0.1 0.2 0.1 0.0 1.1 0.6 0.1 0.1 0.6 0.9 0.3 0.2 0.9 0.4 0.8 C18orf54 "LAS2, MGC33382" ENSG00000166845 "Chromosome 18 open reading frame 54" Q8IYD9 18 54357906-54385218 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.3" "Cell type enhanced" "Detected in many" "Early spermatids: 100.0;Extravillous trophoblasts: 24.0;Late spermatids: 29.7;Oligodendrocytes: 23.0;Spermatocytes: 38.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.8" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040704 Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA040704: AB_10959454" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (5.29e-2)" "unprognostic (8.63e-3)" "unprognostic (2.40e-1)" "unprognostic (1.05e-1)" "unprognostic (5.60e-6)" "unprognostic (1.11e-2)" "unprognostic (7.85e-3)" "unprognostic (2.55e-2)" "unprognostic (5.91e-3)" "unprognostic (1.13e-2)" "unprognostic (3.06e-5)" "unprognostic (2.29e-1)" "unprognostic (4.21e-1)" "unprognostic (1.28e-2)" "unprognostic (7.05e-2)" 2.1 0.6 1.7 2.3 3.5 1.3 1.1 2.6 2.4 1.9 0.6 1.4 0.8 2.3 0.4 1.0 0.9 1.1 0.9 1.5 2.4 0.8 0.4 1.3 3.0 3.4 2.7 1.4 0.2 0.6 0.2 3.1 3.3 0.6 1.3 1.2 0.4 0.8 0.3 1.0 0.8 1.8 2.3 1.7 0.8 17.3 2.6 3.5 0.9 1.2 2.7 1.0 1.0 5.0 10.2 6.6 22.8 11.7 5.8 10.0 8.2 16.0 6.8 15.5 19.6 4.4 5.2 6.9 4.3 5.6 6.4 9.7 16.9 9.3 20.1 26.5 5.2 7.8 7.2 6.1 1.3 9.4 8.0 3.4 1.8 20.9 10.6 6.7 21.6 9.6 7.8 15.6 22.6 3.8 9.7 4.7 12.5 1.6 11.2 7.7 18.3 5.3 7.1 6.9 14.4 7.8 7.0 2.6 4.2 11.7 4.7 6.8 17.5 32.0 13.3 5.3 8.8 9.8 11.8 10.6 8.1 14.5 22.4 0.5 0.2 0.0 0.4 0.3 0.3 0.3 0.3 0.2 0.2 0.4 0.3 0.3 0.0 0.2 1.8 0.1 0.7 0.2 1.7 3.5 2.6 2.4 1.5 2.4 3.4 2.7 3.3 2.3 2.6 5.0 3.9 0.0 0.6 1.6 1.1 0.4 0.7 0.8 0.0 2.2 0.9 0.9 1.5 0.0 0.2 1.8 0.0 0.9 2.3 0.6 0.0 0.2 100.0 1.4 2.3 3.2 0.0 11.2 0.6 0.2 24.0 2.9 0.5 0.8 0.0 14.2 3.6 0.3 2.5 0.0 0.7 0.4 0.0 3.1 2.1 29.7 1.5 1.7 1.8 3.7 1.3 2.4 3.1 4.5 23.0 0.4 0.9 0.7 1.9 0.5 0.2 0.3 0.3 0.9 0.0 2.1 3.0 38.4 14.5 0.8 0.4 2.1 1.2 0.9 1.7 0.8 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C1orf56 "FLJ20519, MENT" ENSG00000143443 "Chromosome 1 open reading frame 56" Q9BUN1 1 151047751-151051986 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 76.5" "Cell type enhanced" "Detected in all" "dendritic cells: 213.9;Early spermatids: 440.4;Langerhans cells: 245.2;Spermatocytes: 308.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 15.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037429, HPA037430" Enhanced "Secreted to blood" NA NA 87000000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA037429: AB_10671755, HPA037430: AB_2675473" "unprognostic (7.60e-2)" "unprognostic (8.26e-2)" "unprognostic (1.09e-2)" "unprognostic (3.83e-1)" "unprognostic (4.31e-2)" "unprognostic (2.83e-2)" "unprognostic (1.11e-2)" "unprognostic (3.81e-3)" "unprognostic (1.59e-2)" "unprognostic (2.70e-3)" "unprognostic (3.28e-3)" "unprognostic (5.29e-2)" "unprognostic (3.61e-2)" "unprognostic (3.61e-2)" "unprognostic (6.16e-2)" "unprognostic (2.26e-1)" "unprognostic (4.79e-2)" 4.6 10.2 2.1 1.5 2.9 0.6 4.4 3.3 2.5 5.7 3.1 4.9 2.1 5.3 3.2 5.4 5.7 2.6 7.9 1.9 2.2 6.5 8.3 2.9 1.6 2.9 2.8 5.9 7.6 3.4 10.0 1.2 2.6 6.4 0.7 1.9 5.5 3.1 6.5 4.2 3.5 1.2 2.9 4.3 5.5 76.5 2.4 0.4 8.2 2.3 0.4 5.1 5.0 3.2 4.1 8.0 2.7 1.2 4.4 4.2 2.4 2.2 3.2 1.4 1.1 3.5 5.6 0.9 3.5 2.4 3.0 5.3 1.5 0.3 0.8 5.2 1.7 1.0 5.9 4.3 3.0 1.1 0.9 3.1 1.7 2.1 0.8 2.7 2.1 1.7 2.2 2.1 1.3 15.9 1.5 2.8 4.5 3.2 4.4 1.3 2.7 2.9 1.2 2.3 3.6 7.0 7.0 3.7 5.5 5.0 7.3 3.0 2.2 1.9 3.3 5.1 2.0 4.7 4.0 12.2 3.5 0.6 2.4 223.6 22.7 50.4 90.8 54.5 70.3 46.7 78.6 80.8 19.7 51.7 64.8 90.8 69.8 59.0 48.2 28.1 48.9 4.1 2.1 2.9 3.3 2.5 1.9 2.2 2.9 2.8 2.6 2.9 2.4 3.2 57.6 6.4 10.1 19.2 56.8 64.6 38.1 20.8 4.6 20.2 80.3 46.2 7.1 40.0 17.1 42.3 20.9 53.8 213.9 15.6 39.2 21.2 440.4 12.3 20.4 34.4 14.8 12.4 27.6 14.5 35.9 34.5 4.1 12.5 38.8 10.7 66.8 38.3 30.9 18.5 25.6 14.4 16.2 95.5 245.2 80.7 28.6 50.4 88.9 24.4 78.0 20.0 119.4 26.7 37.2 32.4 19.5 25.6 50.9 35.7 8.8 36.5 10.8 26.6 26.3 41.4 35.3 308.8 13.7 3.9 83.3 89.5 90.7 11.5 15.0 46.2 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA 410000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" 79.3 135.4 85.5 84.1 85.7 121.2 108.7 91.5 118.3 58.4 119.6 140.3 95.9 66.4 68.3 138.6 74.5 48.7 126.3 89.5 94.3 136.4 134.5 54.7 115.7 89.6 92.3 52.7 72.9 127.7 81.3 75.8 93.2 63.9 141.6 86.7 66.2 73.1 174.2 81.3 78.4 80.9 93.1 73.5 74.3 62.5 90.7 98.5 65.1 160.1 135.6 108.4 73.9 97.3 443.8 671.0 233.0 378.0 169.8 207.7 313.7 330.4 268.5 751.4 458.8 646.8 143.7 941.8 317.8 251.3 271.3 385.8 756.7 448.9 689.8 216.6 1300.5 433.9 312.4 762.2 269.9 535.6 331.0 231.4 404.1 414.6 593.1 181.1 390.0 548.2 526.1 234.4 296.1 308.6 766.4 385.6 525.9 497.2 396.7 601.2 329.1 515.0 440.5 328.7 186.0 348.0 271.4 344.4 483.6 232.1 218.1 267.1 231.1 240.1 219.7 275.9 729.9 122.0 201.2 415.0 229.3 506.2 376.8 68.1 197.6 49.9 217.1 212.0 283.5 330.1 239.0 215.4 389.5 289.8 289.7 245.7 15.5 240.7 166.4 325.4 203.6 432.6 85.5 85.7 91.5 118.3 89.5 94.3 89.6 92.3 93.2 93.1 90.7 97.3 101.6 28.9 30.5 10.7 153.1 243.1 229.0 283.3 165.0 70.5 157.3 209.4 84.8 102.9 107.8 82.8 27.1 323.8 115.0 105.6 313.1 248.0 75.1 106.7 149.9 108.2 79.2 183.1 10.8 205.1 457.9 101.0 94.8 85.9 62.2 131.6 75.3 128.5 202.7 60.6 11.6 190.2 154.6 85.3 129.8 89.5 119.6 101.8 156.5 10.3 170.3 105.2 93.7 11.1 16.1 199.3 128.5 98.6 197.4 255.1 78.9 444.1 65.1 79.9 85.5 101.6 189.1 79.3 237.3 284.4 255.3 179.0 105.5 354.3 364.0 253.8 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 134.0" "Cell type enriched" "Detected in some" 7 "Horizontal cells: 673.0" "Cancer enriched" "Detected in all" 7 "glioma: 116.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 34.8;SH-SY5Y: 24.8;U-2 OS: 89.0;U-251 MG: 28.1;U-87 MG: 27.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (3.40e-3)" "unprognostic (2.34e-1)" "unprognostic (6.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.31e-8)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (3.04e-1)" 7.7 0.7 18.5 0.4 17.2 0.0 0.9 26.6 32.1 3.0 16.2 4.9 2.0 13.0 0.3 1.8 4.4 0.3 4.1 15.5 21.4 21.0 0.7 0.2 0.0 134.0 41.9 0.7 4.6 0.0 2.1 0.0 24.9 7.3 0.3 8.1 0.7 0.0 0.1 0.5 6.2 0.6 32.4 0.1 3.9 0.8 21.6 0.1 0.3 0.2 0.0 6.4 1.2 24.3 4.6 5.1 1.1 17.8 0.3 0.0 0.3 0.8 0.7 0.5 1.6 0.7 0.6 0.2 3.0 0.4 5.3 0.6 2.8 0.2 0.2 12.7 7.5 0.0 7.9 0.1 2.1 0.0 2.2 0.4 0.0 0.7 0.2 6.2 0.0 3.1 0.1 0.2 0.5 1.1 4.0 0.1 3.1 0.5 10.7 6.7 0.2 0.3 0.1 0.4 34.8 24.8 15.6 1.3 1.3 0.9 4.1 0.2 0.1 1.4 89.0 0.9 28.1 1.0 0.0 0.1 27.8 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.5 17.2 26.6 32.1 15.5 21.4 134.0 41.9 24.9 32.4 21.6 24.3 0.1 0.0 0.0 4.2 0.0 0.3 0.2 1.0 0.0 22.3 0.4 3.2 1.1 5.7 0.0 0.0 10.4 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.5 0.4 5.3 0.0 0.5 0.0 0.1 1.9 0.0 0.5 0.0 0.3 1.1 0.1 0.0 673.0 11.7 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 1.0 0.0 17.6 0.0 84.4 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.7 0.2 1.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 C1QL2 "C1QTNF10, CTRP10" ENSG00000144119 "Complement C1q like 2" Q7Z5L3 2 119156243-119158751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 26.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 28.3;Cone photoreceptor cells: 8.4;Oligodendrocyte precursor cells: 37.2" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 2.6" "Region enhanced" "Detected in many" "hippocampal formation: 22.7" "Low region specificity" "Detected in many" HPA057934 Uncertain "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA057934: AB_2683558" "unprognostic (6.95e-2)" "unprognostic (9.74e-2)" "unprognostic (4.48e-3)" "unprognostic (1.08e-1)" "unprognostic (9.91e-4)" "unprognostic (2.60e-5)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" 0.0 0.0 17.6 0.0 9.4 0.0 0.2 3.9 17.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 26.5 16.3 0.0 0.0 0.0 0.1 7.3 7.0 0.1 0.0 0.0 0.5 0.0 6.1 0.0 0.0 2.9 0.0 0.0 0.0 0.4 0.0 0.0 4.5 0.0 0.0 0.2 20.3 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 9.4 3.9 17.0 26.5 16.3 7.3 7.0 6.1 4.5 20.3 8.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 28.3 1.3 0.8 0.5 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 37.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 C1QL3 "C1ql, C1QTNF13, CTRP13, K100" ENSG00000165985 "Complement C1q like 3" Q5VWW1 10 16513734-16521879 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 45.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.5;Excitatory neurons: 4.8;Oligodendrocyte precursor cells: 1.0;Rod photoreceptor cells: 2.9" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 20 "amygdala: 26.8;basal ganglia: 39.1;cerebral cortex: 33.6;hippocampal formation: 45.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HDLM-2: 32.3;SCLC-21H: 19.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 72.1;cerebral cortex: 57.7;hippocampal formation: 51.2" "Secreted in brain" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (7.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (8.19e-3)" "unprognostic (6.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.76e-2)" "unprognostic (2.00e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "prognostic favorable (6.29e-5)" "unprognostic (3.27e-2)" "unprognostic (1.66e-1)" "unprognostic (8.59e-2)" "unprognostic (6.12e-2)" 0.8 0.8 26.8 0.4 39.1 0.1 0.3 0.2 33.6 0.2 0.0 0.3 1.8 0.2 0.0 0.2 0.2 0.1 0.8 45.5 1.2 1.2 0.3 0.4 0.7 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.5 0.0 7.4 0.6 0.0 1.1 0.9 0.7 0.0 0.0 0.5 0.5 0.0 1.2 0.0 1.0 0.1 0.0 0.3 0.2 1.8 0.1 1.8 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 2.1 1.1 3.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 32.3 0.3 1.9 1.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.2 0.2 0.1 1.2 1.2 0.1 1.2 0.3 1.9 0.1 0.7 19.3 1.7 1.8 0.2 1.1 0.3 0.1 0.3 0.0 0.0 0.1 0.9 0.0 0.7 1.1 0.9 0.1 1.8 0.8 0.0 0.2 0.1 0.4 0.4 0.2 0.2 0.3 0.3 0.1 0.2 0.3 0.5 0.0 0.1 0.3 0.2 0.4 0.1 26.8 39.1 0.2 33.6 45.5 1.2 0.0 0.0 0.0 0.0 1.2 1.8 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1QL4 "C1QTNF11, CTRP11" ENSG00000186897 "Complement C1q like 4" Q86Z23 12 49332409-49337188 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.8;testis: 4.2" "Group enriched" "Detected in some" 8 "Early spermatids: 37.2;Horizontal cells: 25.2;Late spermatids: 84.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 35.3;HAP1: 5.5;PC-3: 5.9;U-2 OS: 9.0" "Region enhanced" "Detected in some" "midbrain: 6.2" "Region enhanced" "Detected in some" "pons: 7.6" "Secreted in brain" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.97e-2)" "unprognostic (2.77e-2)" "unprognostic (4.87e-2)" "unprognostic (7.37e-2)" "unprognostic (4.48e-1)" "unprognostic (1.86e-2)" "unprognostic (2.49e-3)" "unprognostic (8.64e-3)" "unprognostic (2.89e-1)" "unprognostic (5.11e-3)" "unprognostic (7.62e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (9.73e-2)" "unprognostic (2.85e-2)" "unprognostic (9.40e-2)" "unprognostic (3.72e-2)" 0.2 0.0 0.5 0.0 1.5 0.0 0.2 0.3 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.9 0.0 0.0 0.0 0.8 7.8 0.0 0.0 0.1 0.2 0.0 3.9 0.1 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 4.2 0.5 0.0 0.9 0.0 0.0 0.0 1.1 0.8 0.4 1.4 0.4 35.3 0.0 0.0 0.1 0.0 0.1 0.5 1.9 0.9 0.1 0.4 2.0 0.0 2.0 0.1 5.5 0.0 0.6 0.1 2.5 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.1 0.4 0.0 1.2 0.2 0.0 0.0 0.9 0.0 0.0 0.7 0.1 5.9 0.2 0.2 0.0 0.1 0.0 0.0 3.0 0.0 0.3 1.6 0.1 0.7 0.2 0.0 0.5 9.0 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.3 0.5 0.2 1.5 0.8 7.8 3.9 0.1 0.5 0.8 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.4 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 25.2 0.0 0.0 0.0 0.0 0.3 84.5 0.9 0.0 3.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 5.6 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 C1QTNF1 "CTRP1, FLJ90694, GIP, ZSIG37" ENSG00000173918 "C1q and TNF related 1" Q9BXJ1 17 79022814-79049788 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 214.2;heart muscle: 319.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 120.0;Sertoli cells: 105.2;Smooth muscle cells: 105.8;Syncytiotrophoblasts: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 313.5;BJ hTERT+: 72.9;HHSteC: 112.3;HSkMC: 61.3;U-87 MG: 66.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025429, HPA051101" Uncertain Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 314000000 40000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB025429: , HPA051101: AB_2681343" "unprognostic (2.58e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (1.20e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" "unprognostic (7.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-2)" "unprognostic (7.48e-2)" "unprognostic (9.81e-3)" "unprognostic (5.83e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (1.95e-2)" 214.2 75.3 9.5 14.8 15.2 0.5 156.0 16.1 13.3 50.2 45.3 38.3 4.6 45.1 6.5 18.9 63.5 24.3 319.1 9.1 18.2 25.3 45.7 44.4 14.0 18.3 25.4 70.5 14.9 13.5 17.5 42.2 18.0 57.1 6.3 0.9 34.9 44.0 27.0 38.6 29.3 13.3 14.1 35.7 25.0 5.4 21.9 5.1 115.0 21.3 6.6 34.7 42.3 13.2 0.1 32.3 0.3 0.1 313.5 27.1 0.2 13.6 72.9 7.0 11.9 2.7 14.0 0.1 1.5 5.1 18.1 0.7 1.0 0.5 5.0 0.1 3.5 0.2 11.7 1.5 112.3 0.1 0.2 61.3 0.2 14.5 0.8 9.3 8.8 1.6 0.1 0.3 1.6 0.1 0.3 0.2 3.0 3.7 27.9 0.1 22.3 0.4 0.0 0.4 1.3 5.3 9.2 1.8 32.7 1.2 0.0 0.0 1.4 32.6 0.8 4.0 4.8 0.3 0.1 0.1 66.2 0.2 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.5 15.2 16.1 13.3 9.1 18.2 18.3 25.4 18.0 14.1 21.9 13.2 36.1 0.0 0.6 4.9 0.4 6.5 0.7 12.3 0.6 0.1 9.2 1.8 10.8 5.7 0.5 1.8 0.0 21.5 0.4 3.2 0.0 19.5 0.1 0.6 17.9 38.3 4.8 2.7 0.2 5.9 1.5 23.6 2.6 0.6 0.0 25.3 120.0 1.9 2.6 0.0 0.9 6.3 2.0 7.5 11.3 0.7 10.5 1.1 3.6 5.6 10.9 0.5 0.0 0.5 0.3 3.7 3.1 3.4 0.1 1.8 0.9 0.2 0.3 0.5 105.2 12.7 105.8 0.0 0.7 0.4 4.5 47.3 0.8 18.1 5.2 0.6 C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;skin 1: 6.6" "Cell type enhanced" "Detected in some" "Adipocytes: 19.5;Extravillous trophoblasts: 11.2;Proximal tubular cells: 45.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 4.1;U-2 OS: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" NA NA 38200000 "Cluster 40: NK-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA024107: AB_2101207" "unprognostic (1.10e-2)" "unprognostic (5.68e-3)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (6.60e-3)" "unprognostic (2.43e-1)" "unprognostic (2.67e-3)" "unprognostic (1.01e-2)" "unprognostic (2.58e-1)" "unprognostic (1.05e-2)" "unprognostic (8.02e-3)" "unprognostic (1.10e-2)" "unprognostic (9.68e-3)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" 1.3 0.1 0.4 0.2 0.4 0.0 0.7 0.3 0.5 0.5 0.0 3.4 6.8 0.3 0.0 1.3 0.5 0.1 0.8 0.4 0.7 3.4 0.5 0.4 0.0 0.8 0.4 0.2 0.2 0.0 0.3 0.2 0.5 0.3 0.7 0.0 0.3 0.0 0.4 6.6 6.7 0.0 0.4 0.2 0.4 2.4 0.9 0.0 0.4 0.0 0.1 0.3 0.6 0.5 0.1 0.0 0.0 0.3 0.2 0.0 0.8 0.6 0.0 0.0 0.0 0.3 0.2 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 0.1 0.4 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 4.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.5 0.4 0.7 0.8 0.4 0.5 0.4 0.9 0.5 19.5 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 3.9 0.5 0.0 0.6 1.2 0.7 0.0 0.0 0.0 0.8 11.2 0.5 0.0 0.7 2.5 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 45.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.0 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1QTNF3 "2310005P21Rik, Corcs, Cors, Cors-26, CTRP3" ENSG00000082196 "C1q and TNF related 3" Q9BXJ4 5 34017858-34043213 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.4;salivary gland: 52.0" "Cell type enhanced" "Detected in many" "Early spermatids: 161.6;Fibroblasts: 61.5;Late spermatids: 387.6;Muller glia cells: 227.2;Skeletal myocytes: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 211 "U-266/84: 810.2" "HPA064996, HPA066011" Uncertain Approved "Golgi apparatus" "Secreted to blood" NA NA 44100000 24000000 "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA064996: AB_2685399, HPA066011: AB_2685597" "unprognostic (7.71e-2)" "unprognostic (2.81e-3)" "unprognostic (5.83e-2)" "unprognostic (6.58e-2)" "unprognostic (3.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-3)" "unprognostic (5.18e-2)" "unprognostic (1.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.89e-3)" "unprognostic (1.80e-1)" "unprognostic (9.38e-3)" "unprognostic (2.35e-1)" 7.3 0.5 4.1 1.7 5.0 0.6 6.8 6.8 4.0 3.6 2.6 11.2 3.5 2.7 1.0 33.4 3.0 5.9 0.9 3.9 7.0 4.8 1.1 4.1 0.8 5.3 4.3 1.4 1.7 0.3 1.3 0.6 4.5 2.2 10.0 23.7 52.0 4.9 2.2 2.3 8.9 23.3 5.8 0.7 10.7 11.4 4.2 1.0 1.6 9.9 0.4 13.2 3.6 5.1 0.7 0.1 0.2 0.3 0.0 0.1 0.3 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.9 0.2 0.0 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.7 0.8 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.8 3.2 0.0 0.0 0.0 1.1 0.1 0.0 0.1 0.2 0.2 1.6 0.0 0.1 0.6 0.1 0.0 3.8 0.6 0.1 1.0 0.0 1.0 0.9 810.2 1.3 0.0 0.8 3.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 4.1 5.0 6.8 4.0 3.9 7.0 5.3 4.3 4.5 5.8 4.2 5.1 2.3 3.2 2.0 0.0 2.0 5.7 0.6 0.4 1.8 5.1 3.0 2.3 1.0 8.6 0.8 3.7 0.0 0.9 1.5 0.7 1.9 1.2 161.6 2.6 1.0 7.2 1.8 1.3 0.0 1.4 0.5 61.5 1.5 2.6 0.0 1.8 0.4 1.3 1.3 8.4 0.0 1.4 2.0 0.6 9.6 387.6 1.8 1.1 7.2 0.0 0.3 227.2 1.0 0.0 0.0 0.5 1.5 2.6 0.2 0.8 0.8 2.1 1.2 11.9 0.0 77.5 4.5 6.2 2.0 1.1 5.8 0.4 1.3 1.0 2.0 0.5 C1QTNF4 "CTRP4, ZACRP4" ENSG00000172247 "C1q and TNF related 4" Q9BXJ3 11 47589667-47594411 "Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.0;pituitary gland: 17.1" "Cell type enhanced" "Detected in many" "Late spermatids: 51.7;Leydig cells: 46.0;Muller glia cells: 54.5;Peritubular cells: 38.4;Spermatogonia: 44.5;Theca cells: 39.0" "Group enriched" "Detected in some" 4 "glioma: 1.7;ovarian cancer: 2.5;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "REH: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041032 Approved Uncertain "Golgi apparatus,Vesicles" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus, Vesicles" "HPA041032: AB_10671170" "unprognostic (1.84e-3)" "unprognostic (1.58e-1)" "unprognostic (8.98e-4)" "unprognostic (8.19e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-3)" "unprognostic (6.78e-2)" "unprognostic (6.11e-2)" "unprognostic (6.35e-2)" "unprognostic (4.00e-1)" "unprognostic (4.91e-4)" "unprognostic (1.22e-1)" "unprognostic (8.22e-6)" "unprognostic (6.02e-3)" "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (6.28e-2)" 1.7 1.5 7.9 0.0 33.0 1.1 2.2 13.2 17.6 5.3 0.0 3.9 0.1 5.8 0.0 0.5 4.2 0.0 1.0 7.5 1.1 1.4 0.9 0.7 0.0 6.0 4.9 12.0 0.4 0.7 17.1 0.0 2.1 2.8 0.0 0.1 1.1 0.1 0.9 1.8 1.5 0.1 1.0 1.0 1.5 5.8 6.7 0.0 1.5 0.0 0.0 1.3 2.0 3.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 33.0 13.2 17.6 7.5 1.1 6.0 4.9 2.1 1.0 6.7 3.4 2.4 0.0 0.0 18.9 0.0 2.4 6.5 0.2 0.0 15.8 1.3 25.8 0.7 1.5 0.3 3.7 16.7 1.3 0.1 0.2 3.9 0.1 11.3 0.8 21.2 4.5 0.0 2.5 15.5 0.2 2.7 20.7 0.5 0.6 0.0 31.3 2.5 0.2 3.3 5.0 17.8 0.1 0.0 0.3 3.0 51.7 46.0 0.7 10.6 4.7 0.0 54.5 0.0 5.0 8.0 0.1 0.1 38.4 0.0 4.3 0.1 0.6 0.6 24.7 26.3 12.8 8.5 13.5 44.5 0.3 1.8 3.6 0.6 39.0 0.2 2.4 C1QTNF5 "CTRP5, DKFZp586B0621, LORD" ENSG00000223953 "C1q and TNF related 5" Q9BXJ0 11 119338942-119340940 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 4.7;Endothelial cells: 1.5;Exocrine glandular cells: 1.1;Fibroblasts: 3.6;Gastric mucus-secreting cells: 1.5;Smooth muscle cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 17.7;fHDF/TERT166: 14.7;HHSteC: 35.8;hTERT-RPE1: 28.5;HUVEC TERT2: 54.7;TIME: 50.5" "Low region specificity" "Detected in all" "CAB025607, HPA038604" Uncertain "Secreted to blood" NA NA 219000000 1500000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB025607: , HPA038604: AB_2676110" 51.9 13.4 19.1 12.9 20.8 0.1 36.6 20.3 20.7 38.4 25.5 23.0 14.9 50.7 7.5 11.5 27.2 45.5 36.1 17.3 19.8 42.4 11.1 42.0 8.9 21.8 22.2 11.3 18.8 6.8 14.8 13.6 20.4 19.5 7.8 2.2 16.9 8.7 8.8 20.4 24.2 26.8 21.7 32.3 27.1 2.6 27.5 2.8 32.0 15.2 4.6 31.6 20.8 21.7 0.0 0.0 3.3 0.0 17.7 4.9 0.2 4.6 0.3 0.6 2.7 0.1 0.0 0.1 2.0 14.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 35.8 0.0 0.0 8.4 0.0 0.3 0.0 28.5 54.7 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.9 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.0 6.5 0.0 0.0 1.1 0.9 0.0 0.0 50.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 20.8 20.3 20.7 17.3 19.8 21.8 22.2 20.4 21.7 27.5 21.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 1.5 0.0 0.0 0.0 1.1 0.0 3.6 1.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 C1QTNF6 "CTRP6, ZACRP6" ENSG00000133466 "C1q and TNF related 6" Q9BXI9 22 37180166-37199385 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.7;placenta: 29.6" "Cell type enriched" "Detected in many" 11 "Extravillous trophoblasts: 398.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 114.2;RT4: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002042 Enhanced Approved Nucleoplasm "Secreted to blood" No No 354000000 "Cluster 48: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA002042: AB_1078342" "unprognostic (9.65e-2)" "unprognostic (1.21e-2)" "unprognostic (2.32e-1)" "unprognostic (2.23e-3)" "unprognostic (1.25e-3)" "unprognostic (3.01e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.60e-6)" "unprognostic (6.96e-2)" "unprognostic (5.11e-2)" "unprognostic (2.61e-2)" "unprognostic (1.72e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.61e-2)" "unprognostic (5.36e-2)" "unprognostic (1.08e-3)" "unprognostic (1.52e-2)" 4.9 6.7 4.4 6.6 4.5 1.6 4.0 4.3 5.3 11.1 4.3 5.5 1.6 31.7 1.4 2.7 7.0 8.8 3.7 4.5 4.3 7.4 13.0 5.2 5.1 5.1 4.5 5.5 3.5 2.2 2.5 29.6 4.8 6.8 3.6 0.5 3.2 2.9 1.5 5.0 5.4 8.2 4.4 6.5 3.5 6.2 4.8 2.4 3.8 0.7 2.3 5.6 4.3 6.3 17.7 20.5 10.7 3.6 1.8 21.3 32.6 3.4 6.8 2.8 2.0 3.8 24.7 0.1 14.1 6.0 1.5 34.9 0.4 8.4 1.2 4.9 2.6 2.8 8.3 3.8 7.1 0.1 2.3 29.2 4.9 2.3 0.6 7.3 25.5 0.8 0.1 7.7 1.1 114.2 0.0 0.5 7.1 2.5 0.3 0.2 0.1 2.8 24.5 50.7 1.8 14.6 1.0 19.7 2.8 5.5 7.0 0.5 9.4 1.1 5.6 0.4 0.1 15.5 0.4 0.1 2.1 2.0 3.2 0.4 0.1 0.5 0.2 0.2 0.2 0.2 0.4 0.3 0.1 0.7 0.9 0.7 0.5 1.5 0.1 0.3 1.4 0.3 4.4 4.5 4.3 5.3 4.5 4.3 5.1 4.5 4.8 4.4 4.8 6.3 3.2 0.0 0.0 13.7 2.9 1.5 2.1 1.9 0.6 1.0 8.6 4.2 1.8 1.5 2.2 1.8 0.0 8.1 1.5 7.9 1.9 3.4 2.0 4.8 30.8 6.8 0.0 0.8 3.3 1.1 398.9 7.6 2.0 9.6 1.3 19.8 10.0 7.2 9.3 0.0 4.3 3.1 0.0 1.9 1.4 8.9 0.6 1.2 5.4 3.7 1.1 4.5 1.0 4.0 7.8 2.7 2.8 0.4 3.4 0.8 2.0 1.6 2.7 0.9 0.0 2.2 7.5 7.2 4.5 1.0 0.3 34.5 3.1 7.6 4.4 1.5 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C1QTNF8 "CTRP8, UNQ5829" ENSG00000184471 "C1q and TNF related 8" P60827 16 1088226-1096244 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.8;fallopian tube: 1.8;pituitary gland: 2.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Endometrial ciliated cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056438 Uncertain "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 49: Ciliated cells - Cilium organization" "HPA056438: AB_2683134" "unprognostic (8.65e-2)" "unprognostic (2.56e-2)" "unprognostic (5.46e-2)" 0.0 0.3 0.4 0.0 0.4 0.0 0.0 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.9 0.0 0.0 0.1 0.0 1.9 2.8 0.0 0.0 0.0 2.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.4 0.5 0.9 1.9 2.8 1.2 2.1 0.8 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1QTNF9 "AQL1, C1QTNF9A, CTRP9, MGC48915" ENSG00000240654 "C1q and TNF related 9" P0C862 13 24307166-24322535 "Predicted secreted proteins, Transporters" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 8.4" "Group enriched" "Detected in some" 10 "Adipocytes: 34.9;Endothelial cells: 12.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056632 Uncertain "Secreted to blood" NA NA 210000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA056632: AB_2683197" "unprognostic (1.18e-2)" "unprognostic (3.22e-2)" "unprognostic (2.44e-2)" "unprognostic (3.14e-3)" "unprognostic (9.22e-2)" "unprognostic (1.48e-1)" "unprognostic (1.96e-2)" "unprognostic (3.63e-2)" "unprognostic (1.03e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-2)" "unprognostic (4.16e-2)" "unprognostic (3.29e-4)" "unprognostic (1.38e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (2.22e-1)" 3.1 0.2 0.3 0.1 0.2 0.2 1.5 0.4 0.3 0.3 0.0 1.6 0.6 0.3 0.4 0.4 0.3 0.8 3.8 1.9 0.5 0.3 0.5 0.2 0.2 0.1 0.1 0.1 0.6 0.1 0.1 1.3 0.2 0.6 0.3 0.4 0.4 0.1 8.4 2.1 0.6 0.6 0.0 0.3 0.5 0.9 0.2 0.2 0.2 3.3 0.1 0.8 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.3 1.9 0.5 0.1 0.1 0.2 0.0 0.2 0.2 34.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.3 2.2 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.1 2.0 0.5 0.1 12.9 0.0 0.0 0.2 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.9 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.1 C1QTNF9B CTRP9B ENSG00000205863 "C1q and TNF related 9B" B2RNN3 13 23891099-23897502 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.8;skin 1: 17.9;testis: 8.8" "Cell type enhanced" "Detected in some" "Adipocytes: 4.3;Early spermatids: 2.3;Endothelial cells: 1.4;Late spermatids: 2.1" "Cancer enhanced" "Detected in single" "prostate cancer: 0.8" "Region enriched" "Detected in many" 4 "hippocampal formation: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 4.8;OE19: 3.6" HPA056632 Uncertain "Secreted - unknown location" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA056632: AB_2683197" "unprognostic (3.43e-1)" "unprognostic (3.42e-1)" "unprognostic (2.18e-2)" "unprognostic (9.51e-2)" "unprognostic (2.18e-1)" "unprognostic (4.10e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-3)" "unprognostic (1.52e-2)" "unprognostic (7.26e-2)" "unprognostic (3.01e-3)" "unprognostic (7.04e-2)" "unprognostic (5.56e-3)" "unprognostic (3.89e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" 1.2 0.7 1.0 0.6 0.9 0.2 0.4 0.3 1.2 0.3 0.4 0.4 0.5 0.7 0.0 1.6 0.3 0.8 3.5 7.8 1.9 0.2 0.1 0.4 0.2 0.3 0.6 0.4 0.6 0.1 1.1 0.6 0.3 4.2 0.1 0.7 1.6 0.2 4.0 17.9 0.2 0.7 0.3 1.3 0.8 8.8 0.7 0.0 0.5 2.0 0.0 0.6 0.1 0.4 0.7 1.7 0.6 0.7 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 1.3 1.7 0.0 0.0 0.0 1.0 1.4 0.3 0.9 0.9 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 4.8 0.4 0.9 0.0 1.1 0.2 0.0 1.1 3.6 1.6 0.6 0.8 1.3 0.0 0.0 2.0 0.0 1.0 0.0 1.7 0.4 0.5 0.2 0.1 1.6 0.4 0.0 1.0 1.4 0.2 0.7 1.9 0.6 0.3 0.0 0.2 0.4 0.3 0.3 0.1 0.2 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.4 0.4 0.7 0.0 0.1 1.0 0.9 0.3 1.2 7.8 1.9 0.3 0.6 0.3 0.3 0.7 0.4 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.9 0.0 0.3 0.0 0.0 0.4 0.0 0.0 C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109238 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 54.2;Hepatocytes: 140.0;Leydig cells: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.2;HSkMC: 43.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011338, CAB026172" Supported "Secreted to blood" NA NA 5500000000 15000000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026172: , HPA011338: AB_1847111" "prognostic favorable (7.92e-4)" "unprognostic (7.76e-2)" "unprognostic (3.91e-3)" "unprognostic (5.25e-3)" "unprognostic (2.92e-3)" "unprognostic (9.60e-2)" "unprognostic (2.75e-3)" "unprognostic (7.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (9.58e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.75e-1)" "unprognostic (5.74e-2)" "unprognostic (2.52e-1)" "unprognostic (2.26e-3)" 38.3 72.5 3.4 12.2 3.3 8.2 36.5 2.6 3.1 38.6 7.1 28.8 7.6 30.2 6.3 17.5 40.8 11.7 18.4 2.7 4.0 20.1 141.9 33.1 9.5 7.4 5.0 49.4 36.7 8.0 17.5 5.1 4.4 29.3 8.7 1.5 33.7 6.9 11.0 18.1 26.3 13.7 3.7 32.3 27.5 6.1 3.9 6.9 21.7 6.0 7.7 38.1 27.5 3.3 3.0 7.7 0.7 7.9 22.4 38.2 5.4 4.9 22.7 5.0 14.8 4.9 13.4 1.3 4.1 4.1 5.0 6.4 2.1 8.1 1.9 12.0 0.4 4.8 8.5 11.4 18.7 1.0 21.9 43.1 15.7 3.0 9.3 23.3 5.3 2.8 3.6 3.1 3.1 0.1 0.7 0.9 1.4 0.6 0.2 2.7 0.0 1.0 13.1 13.2 0.6 1.7 16.7 2.0 2.8 1.3 1.9 4.1 5.0 4.3 7.7 4.9 0.9 2.3 1.0 0.2 8.1 3.4 2.0 3.8 0.7 4.0 0.6 1.1 0.3 1.2 0.6 0.5 0.8 0.5 0.4 0.4 5.4 0.3 1.3 0.4 0.4 0.4 3.4 3.3 2.6 3.1 2.7 4.0 7.4 5.0 4.4 3.7 3.9 3.3 11.0 16.0 38.6 7.5 8.4 3.8 15.4 16.4 25.6 0.5 15.6 14.5 2.6 30.0 24.6 5.5 2.1 0.2 7.3 8.3 1.9 36.3 0.1 7.9 22.6 14.6 4.2 7.8 10.2 54.2 0.4 29.0 27.5 10.4 3.8 13.8 25.0 140.0 3.6 0.0 1.3 7.7 10.2 10.0 4.9 3.0 55.6 10.2 3.6 14.0 13.3 4.0 21.6 2.0 0.4 25.8 9.7 20.3 8.0 10.2 9.3 8.2 15.9 1.1 0.0 11.8 10.1 0.6 0.9 8.5 3.1 0.1 9.7 13.6 9.5 8.7 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 477.9" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 142.4;Hepatocytes: 380.3;Hofbauer cells: 282.7;Kupffer cells: 99.3" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 21.1;non-classical monocyte: 25.9" "Lineage enriched" "Detected in single" 35 "monocytes: 25.9" "Cell line enriched" "Detected in some" 5 "Karpas-707: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" NA NA 34000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 42.6 12.1 0.8 27.6 1.0 3.2 11.7 0.9 1.4 8.1 1.7 14.3 16.7 7.0 1.3 7.6 12.0 23.0 8.5 0.7 1.1 23.2 477.9 80.0 27.8 3.0 2.6 5.3 1.9 0.9 3.8 48.4 3.0 5.4 13.0 0.4 9.1 0.9 2.1 5.8 30.2 23.6 2.1 46.3 12.0 4.1 3.7 5.5 3.3 2.7 12.5 23.6 5.3 2.1 0.3 0.1 0.1 0.6 0.1 0.0 6.8 0.5 0.3 0.4 0.3 0.4 0.3 0.6 3.5 1.0 0.6 0.5 0.1 0.0 0.3 0.2 0.4 0.3 0.4 52.8 1.1 0.1 0.7 2.7 0.3 0.6 0.1 0.6 0.0 0.7 0.5 284.0 0.0 0.0 0.4 0.5 0.3 0.1 0.0 0.2 16.5 3.0 0.0 0.1 0.3 0.3 2.6 0.3 0.2 0.3 0.2 9.5 0.2 0.2 0.7 0.5 0.1 0.9 31.6 2.7 0.8 0.9 0.1 0.1 5.6 0.0 0.1 21.1 0.1 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.5 0.1 25.9 0.0 0.0 2.2 0.8 1.0 0.9 1.4 0.7 1.1 3.0 2.6 3.0 2.1 3.7 2.1 2.1 25.6 142.4 2.6 1.9 3.3 1.1 2.0 0.6 1.4 1.3 1.3 0.6 25.8 11.2 1.8 0.0 2.1 0.1 1.8 0.0 0.6 0.3 1.5 18.7 1.9 2.4 10.7 6.6 2.7 2.7 19.8 3.1 1.3 3.8 0.2 21.0 380.3 282.7 1.7 6.3 11.3 0.0 99.3 5.0 1.3 6.8 32.6 3.6 7.5 7.3 0.1 0.0 1.0 1.7 4.5 33.1 1.2 0.4 4.0 55.2 35.7 9.4 0.9 0.0 5.6 3.5 0.8 1.4 0.7 2.8 4.0 2.0 0.5 15.8 4.5 C21orf62 "B37, C21orf120, PRED81" ENSG00000205929 "Chromosome 21 open reading frame 62" Q9NYP8 21 32790673-32813743 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 19.7;ovary: 14.2" "Group enriched" "Detected in many" 4 "Cholangiocytes: 44.3;Distal tubular cells: 23.5;Skeletal myocytes: 26.2" "Cancer enriched" "Detected in some" 6 "glioma: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 3.8;RPTEC TERT1: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016899 Enhanced "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA016899: AB_1845704" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (1.23e-1)" "unprognostic (4.37e-3)" "unprognostic (9.56e-2)" "unprognostic (3.05e-3)" "unprognostic (2.95e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.59e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" 1.6 0.3 1.7 0.4 2.2 0.5 0.1 1.8 2.0 0.0 19.7 0.1 0.1 0.0 8.4 0.2 0.7 0.4 0.2 2.4 4.1 6.9 0.2 0.1 0.2 3.2 7.2 14.2 4.1 0.0 3.4 0.0 2.8 3.6 0.0 1.0 0.1 0.2 0.1 0.2 0.4 0.2 2.0 0.2 0.3 0.3 4.6 0.0 0.1 0.1 1.1 0.0 0.1 5.8 0.0 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.7 0.2 0.0 0.1 0.3 0.0 1.7 2.2 1.8 2.0 2.4 4.1 3.2 7.2 2.8 2.0 4.6 5.8 0.0 0.0 0.0 2.9 0.5 0.9 0.8 0.4 0.0 5.9 0.0 0.0 0.2 44.3 0.3 5.5 6.2 1.2 1.3 0.1 23.5 0.2 1.5 0.0 0.0 0.8 3.0 0.0 0.8 0.0 0.4 3.6 0.0 0.0 0.0 0.2 2.5 0.2 0.3 0.0 1.4 0.0 0.0 1.3 1.9 0.3 4.1 0.4 3.6 0.0 1.0 5.8 4.1 4.0 4.7 0.0 0.0 1.9 0.0 0.5 0.1 2.6 0.2 7.1 0.0 26.2 1.7 1.0 1.0 0.0 1.0 0.3 1.1 0.2 0.2 0.4 C22orf15 "FLJ36561, N27C7-3" ENSG00000169314 "Chromosome 22 open reading frame 15" Q8WYQ4 22 23762990-23765863 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "fallopian tube: 18.3" "Cell type enriched" "Detected in some" 5 "Respiratory ciliated cells: 198.2" "Cancer enriched" "Detected in single" 4 "endometrial cancer: 1.7" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 1.2;BJ: 1.2;BJ hTERT+: 2.3;hTERT-RPE1: 3.2;MOLT-4: 1.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.37e-2)" "unprognostic (3.28e-3)" "unprognostic (1.28e-1)" "prognostic favorable (8.53e-5)" "unprognostic (1.86e-2)" "unprognostic (2.07e-2)" "unprognostic (4.38e-2)" "unprognostic (6.14e-2)" "unprognostic (3.60e-2)" "unprognostic (7.70e-2)" "unprognostic (4.58e-2)" "unprognostic (2.60e-1)" "unprognostic (9.79e-2)" "unprognostic (2.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.28e-2)" "unprognostic (3.08e-3)" 0.1 0.0 0.3 0.0 0.2 0.3 0.1 0.2 0.2 0.4 0.5 0.2 0.0 0.2 0.0 0.0 18.3 0.2 0.0 0.3 0.6 0.1 0.0 1.8 0.1 1.1 1.6 0.5 0.0 0.0 1.0 0.2 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.2 0.1 2.8 0.3 1.0 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.1 1.2 0.0 0.0 0.0 0.0 1.2 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.3 0.2 0.1 0.1 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.3 0.2 0.2 0.2 0.3 0.6 1.1 1.6 1.1 0.8 0.3 0.2 0.0 0.0 1.8 1.3 0.0 0.1 0.0 9.1 0.0 0.5 0.0 0.5 0.1 0.0 15.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 6.0 35.8 0.2 0.2 0.0 0.4 2.3 0.0 0.0 1.4 0.0 0.3 2.5 0.1 0.7 0.1 0.0 0.0 2.0 0.0 16.2 0.3 0.4 3.5 0.0 0.3 0.0 1.0 0.1 0.2 0.0 0.5 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 198.2 1.9 0.0 0.1 3.5 10.9 4.2 0.0 0.3 0.0 1.0 0.5 0.0 0.1 C2orf66 UNQ6411 ENSG00000187944 "Chromosome 2 open reading frame 66" 2 196804417-196809355 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adrenal gland: 3.9;brain: 5.1;pituitary gland: 3.7" "Cell type enriched" "Detected in some" 7 "Early spermatids: 36.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 9.0;RT4: 2.2;TIME: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA020869 Uncertain Uncertain Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 36: HEL - Hemostasis" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA020869: AB_1851545" "unprognostic (1.19e-1)" "unprognostic (4.85e-2)" "unprognostic (6.95e-2)" "unprognostic (1.19e-1)" "unprognostic (3.48e-2)" "unprognostic (1.61e-2)" "unprognostic (6.80e-3)" "unprognostic (3.05e-2)" "unprognostic (1.95e-1)" "unprognostic (4.10e-3)" "unprognostic (4.54e-4)" "unprognostic (1.98e-1)" "unprognostic (1.75e-5)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (1.86e-2)" 2.8 3.9 2.1 0.2 1.8 0.1 0.4 1.4 2.2 0.0 1.7 0.3 0.0 0.1 0.4 0.2 0.6 0.3 0.5 2.0 4.2 0.2 0.1 0.3 0.0 2.3 5.1 0.3 0.4 0.1 3.7 0.0 2.9 0.3 0.1 1.8 0.1 0.1 0.0 1.2 0.3 0.0 1.5 0.1 0.2 1.5 2.8 0.1 0.1 0.0 0.1 0.3 0.2 1.6 0.0 0.1 0.2 0.8 0.2 0.2 0.0 0.3 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.4 9.0 0.3 0.1 0.0 0.1 0.8 0.2 1.2 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.4 2.2 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.1 2.1 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.8 1.4 2.2 2.0 4.2 2.3 5.1 2.9 1.5 2.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 C2orf69 FLJ38973 ENSG00000178074 "Chromosome 2 open reading frame 69" Q8N8R5 2 199911293-199955935 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 132.1;Spermatocytes: 124.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045225 Approved "Secreted to blood" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA045225: AB_10960841" "unprognostic (6.94e-3)" "unprognostic (1.09e-1)" "unprognostic (7.17e-2)" "unprognostic (3.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (4.39e-3)" "unprognostic (1.92e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.33e-3)" "unprognostic (1.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.41e-3)" "unprognostic (8.87e-2)" "unprognostic (1.03e-2)" "unprognostic (5.86e-2)" 9.7 14.1 8.5 6.8 8.7 22.1 7.4 7.7 12.4 5.7 6.3 8.0 8.4 6.4 6.5 6.8 3.8 6.2 6.7 9.6 9.2 8.9 10.0 6.0 7.3 7.7 8.3 4.8 8.2 9.2 4.1 5.3 7.8 6.5 8.0 10.4 6.2 4.7 9.1 6.4 7.4 7.6 8.4 7.0 7.1 14.7 9.3 5.2 6.7 9.8 7.4 6.8 4.0 10.0 16.1 7.2 13.2 18.0 18.2 22.8 22.3 22.6 13.5 15.0 17.7 16.3 11.4 13.2 12.9 16.0 15.9 12.8 14.1 12.0 25.1 19.8 12.8 20.4 12.4 20.8 10.6 20.7 24.2 11.8 10.5 17.2 14.9 8.1 17.0 8.8 14.9 25.5 25.6 13.9 11.6 18.1 19.4 7.1 19.1 11.0 17.2 11.9 14.8 16.4 21.5 9.4 10.9 8.1 17.4 16.9 12.0 17.7 14.9 23.3 19.0 26.2 18.2 16.7 29.0 13.0 18.6 13.1 12.0 5.4 2.7 7.2 3.6 3.5 5.2 3.1 4.0 3.4 2.4 3.0 4.2 4.5 2.3 2.0 2.7 1.3 4.1 2.8 8.5 8.7 7.7 12.4 9.6 9.2 7.7 8.3 7.8 8.4 9.3 10.0 13.5 3.2 5.1 12.4 22.9 38.0 29.8 8.8 9.1 21.8 10.1 3.7 11.4 12.8 7.6 16.5 29.2 13.3 11.0 16.4 27.4 12.8 132.1 7.9 10.2 16.1 18.6 27.8 19.4 18.3 18.0 17.0 13.7 7.1 8.2 14.8 23.6 19.7 11.8 13.5 13.9 16.9 10.2 18.0 32.1 78.1 13.4 13.4 16.0 12.2 14.0 56.5 12.3 12.5 27.0 14.6 9.3 21.8 8.6 24.6 18.1 20.4 11.8 26.5 19.7 14.0 14.9 124.3 44.1 15.7 44.9 9.9 18.1 11.1 17.5 19.5 C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 4761.3" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 4512.2" "Cancer enriched" "Detected in all" 5 "liver cancer: 1213.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "non-classical monocyte: 13.3" "Lineage enriched" "Detected in many" 4 "monocytes: 13.3" "Group enriched" "Detected in many" 7 "BJ hTERT+: 357.8;EFO-21: 738.6;Hep G2: 795.3;HSkMC: 534.8;SiHa: 209.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" NA NA 1260000000000 200000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB004209: AB_627277, HPA003563: AB_1847117, HPA020432: AB_1847118" "unprognostic (3.26e-3)" "unprognostic (3.91e-1)" "unprognostic (3.92e-1)" "unprognostic (5.98e-3)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.99e-1)" "unprognostic (9.26e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.88e-1)" 585.2 286.5 46.0 194.3 53.7 1.5 213.9 47.8 46.0 237.5 31.5 128.9 22.9 82.9 41.1 76.4 350.3 354.9 221.6 36.5 81.8 51.4 4761.3 176.0 68.2 143.3 99.2 228.1 182.7 17.9 21.8 17.7 116.4 35.4 76.5 11.7 155.6 57.4 36.6 51.4 156.4 123.0 89.9 7.1 107.9 41.1 103.4 34.1 92.4 52.0 126.4 363.3 101.3 121.9 65.0 23.0 0.0 0.1 10.8 36.0 74.7 5.2 357.8 6.8 12.6 3.6 49.5 1.9 738.6 0.3 54.2 46.6 0.2 43.1 6.9 24.0 0.5 3.1 31.2 795.3 16.3 6.2 9.1 534.8 12.8 60.8 27.3 9.5 0.0 0.0 2.1 0.8 0.2 1.0 0.6 1.6 1.5 0.7 0.1 0.4 5.0 0.3 32.1 6.2 0.5 0.5 209.5 0.1 0.5 0.1 17.2 8.8 3.5 5.7 7.4 4.8 3.6 1.6 4.8 4.5 75.1 4.5 0.3 1.7 1.3 0.6 0.3 2.5 0.2 0.5 0.2 0.1 0.7 0.5 0.2 0.2 3.0 1.3 13.3 0.5 0.1 0.9 46.0 53.7 47.8 46.0 36.5 81.8 143.3 99.2 116.4 89.9 103.4 121.9 36.4 76.9 473.9 0.7 29.4 27.5 14.7 141.5 0.6 0.7 19.5 23.4 14.5 783.5 422.5 16.5 0.0 1.4 2.0 0.2 5.9 494.1 45.9 23.0 63.5 26.2 0.0 209.9 0.4 136.7 1.4 482.2 17.9 57.7 5.1 0.1 124.9 4512.2 34.4 0.0 0.5 0.9 20.3 164.5 44.8 97.5 226.2 45.1 35.6 70.3 14.6 1.2 0.0 0.5 0.6 376.4 0.2 10.9 3.9 13.3 1.9 53.6 177.5 4.6 6.6 20.1 49.1 4.0 7.7 5.2 21.9 2.7 15.0 0.1 0.4 38.2 C3orf33 "AC3-33, FLJ31139" ENSG00000174928 "Chromosome 3 open reading frame 33" Q6P1S2 3 155762617-155806278 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037663 Uncertain "Secreted in other tissues" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA037663: AB_10672610" "unprognostic (1.18e-1)" "unprognostic (9.39e-3)" "unprognostic (1.48e-1)" "unprognostic (1.66e-3)" "unprognostic (1.31e-1)" "unprognostic (7.27e-2)" "unprognostic (6.31e-3)" "unprognostic (3.28e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic favorable (6.48e-7)" "unprognostic (3.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.24e-2)" "unprognostic (1.56e-1)" 2.7 10.7 5.2 1.3 5.6 2.0 4.2 5.3 7.8 4.0 6.2 3.1 2.6 3.7 5.8 1.7 3.9 2.3 6.1 5.5 5.5 6.2 3.1 3.3 1.6 5.4 5.5 4.5 6.7 7.5 4.9 1.3 5.4 4.4 2.3 2.7 3.2 3.9 4.9 1.3 2.2 3.3 5.4 2.3 3.1 4.1 5.8 1.5 8.7 4.4 1.0 2.7 2.5 5.4 5.5 7.5 3.6 4.9 0.3 4.4 1.5 2.4 3.5 2.2 5.2 2.6 6.9 0.9 5.3 2.3 3.3 0.8 3.7 0.0 3.9 2.7 5.4 3.3 1.0 7.0 6.0 4.8 1.1 3.4 4.0 2.4 4.6 2.8 3.8 5.5 5.4 2.4 3.8 4.1 4.9 4.0 4.6 5.2 1.8 4.8 1.8 5.2 12.2 2.7 2.6 3.6 5.3 6.7 4.6 1.8 9.8 5.7 2.3 2.5 1.8 5.5 5.9 4.1 4.3 0.0 1.8 4.4 2.6 2.1 1.2 0.2 4.0 1.1 5.1 1.8 3.1 3.6 2.1 1.4 3.9 4.1 0.1 4.0 0.8 1.7 2.2 2.1 5.2 5.6 5.3 7.8 5.5 5.5 5.4 5.5 5.4 5.4 5.8 5.4 1.6 3.2 6.7 13.7 1.5 1.3 5.2 4.7 5.2 8.5 3.1 2.7 11.9 5.7 6.7 0.0 6.2 4.2 0.9 1.8 5.9 3.7 6.6 1.5 2.7 2.3 3.6 3.8 14.9 3.3 3.1 4.8 1.1 1.4 7.0 2.8 2.5 3.3 2.4 6.7 14.9 3.8 4.1 0.3 2.0 5.4 6.2 1.4 1.8 3.7 0.6 15.6 6.2 11.6 10.7 1.4 2.5 7.9 2.2 5.1 1.0 7.0 3.5 7.6 0.0 8.4 4.1 14.5 14.8 2.7 1.4 3.7 2.8 3.8 3.7 2.5 C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 115.8;liver: 336.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 46.4;Cardiomyocytes: 8.3;Club cells: 13.6;Fibroblasts: 19.1" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 58.5;HSkMC: 72.8;U-266/70: 17.1;U-266/84: 33.9" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" NA NA 342000000 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" 27.9 115.8 0.2 10.6 1.6 0.4 15.7 0.3 2.2 12.6 0.2 31.3 7.5 16.9 11.8 2.6 29.9 2.3 21.8 0.5 1.2 43.1 336.8 14.9 4.5 5.8 1.9 57.5 23.0 0.6 20.6 0.5 2.3 11.1 3.7 5.5 14.2 0.0 1.7 1.7 17.0 0.0 0.5 15.3 11.7 4.1 1.7 4.2 44.5 0.0 2.9 23.1 4.1 1.4 0.0 0.3 0.0 0.0 1.0 5.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.7 0.2 0.1 0.1 0.4 0.0 58.5 0.5 0.0 0.3 1.0 0.0 0.0 0.0 72.8 0.0 0.0 0.0 0.5 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.2 17.1 33.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.3 2.2 0.5 1.2 5.8 1.9 2.3 0.5 1.7 1.4 0.0 9.6 46.4 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 8.3 2.8 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.5 4.4 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 C4B "C4B1, C4B3, C4F, CH, CO4, CPAMD3" ENSG00000224389 "Complement C4B (Chido blood group)" P0C0L5 6 32014795-32035418 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 221.5;liver: 385.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 103.9;Cardiomyocytes: 71.8;Club cells: 22.9;Fibroblasts: 53.9" "Cancer enhanced" "Detected in many" "liver cancer: 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 129.8" "HPA046356, HPA048287, HPA050103" Approved "Secreted to blood" NA NA 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (5.50e-3)" "unprognostic (1.30e-1)" "unprognostic (8.09e-2)" "unprognostic (6.24e-2)" "unprognostic (6.09e-2)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.12e-1)" "unprognostic (6.24e-2)" "unprognostic (6.86e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.99e-3)" "unprognostic (1.11e-2)" 29.7 221.5 4.0 0.4 2.5 0.6 15.9 2.5 2.3 10.3 2.4 27.3 2.0 16.6 0.0 2.2 24.0 5.9 22.7 3.2 13.3 39.8 385.2 13.6 2.7 7.1 12.4 56.5 25.1 1.1 20.1 1.6 7.7 10.2 6.0 2.5 21.0 1.2 1.3 1.1 16.6 9.7 9.9 16.3 10.3 3.1 11.8 7.5 49.1 0.2 4.3 18.5 3.7 11.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 21.0 7.8 0.5 0.0 26.2 0.1 0.0 0.0 2.6 0.0 0.0 0.0 129.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.5 2.5 2.3 3.2 13.3 7.1 12.4 7.7 9.9 11.8 11.6 0.0 3.2 103.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 71.8 1.5 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.6 0.0 0.0 0.0 0.2 0.0 53.9 0.0 0.0 1.3 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.1 0.0 0.5 8.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 C4BPA C4BP ENSG00000123838 "Complement component 4 binding protein alpha" P04003 1 207104233-207144972 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 1918.6" "Group enriched" "Detected in many" 14 "Alveolar cells type 1: 493.6;Alveolar cells type 2: 660.8;Hepatocytes: 1020.8" "Cancer enriched" "Detected in many" 7 "liver cancer: 434.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "neutrophil: 29.5" "Lineage enriched" "Detected in single" 137 "granulocytes: 29.5" "Cell line enriched" "Detected in some" 5 "Hep G2: 37.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000926, HPA001578" Enhanced "Secreted to blood" NA NA 30800000000 28000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA000926: AB_1078355, HPA001578: AB_1078354" "unprognostic (3.85e-4)" "unprognostic (9.07e-2)" "unprognostic (2.06e-1)" "prognostic favorable (6.37e-5)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.24e-4)" "unprognostic (3.64e-2)" "unprognostic (1.94e-1)" "unprognostic (5.90e-4)" "unprognostic (4.47e-2)" "unprognostic (2.58e-1)" "unprognostic (5.51e-7)" "unprognostic (9.74e-2)" "unprognostic (2.52e-2)" "unprognostic (6.92e-2)" "unprognostic (2.66e-1)" 1.4 0.7 0.4 2.5 0.2 0.1 4.5 0.7 0.2 6.3 0.0 1.7 0.0 4.5 0.0 0.1 1.0 3.2 0.2 0.1 0.7 0.6 1918.6 173.3 0.3 0.4 0.2 1.5 9.6 0.2 0.1 0.7 0.5 0.1 0.8 0.0 1.1 0.0 0.0 0.0 0.8 0.1 0.1 1.2 0.4 0.3 0.3 0.0 0.1 0.0 1.1 0.1 0.0 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 37.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 7.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.7 0.2 0.1 0.7 0.4 0.2 0.5 0.1 0.3 0.4 0.0 493.6 660.8 0.0 3.7 0.0 0.0 0.2 0.0 0.0 2.7 0.4 0.2 41.5 22.5 0.0 0.0 0.0 0.0 3.2 0.0 11.2 0.3 18.0 7.6 1.9 0.0 21.5 0.7 18.7 0.0 1.1 0.0 48.8 3.8 0.0 22.1 1020.8 0.2 0.0 1.4 0.3 0.0 39.2 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 5.6 32.0 0.0 0.0 0.3 0.1 0.1 3.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 3.9 16.7 0.2 1.4 C4BPB C4BP ENSG00000123843 "Complement component 4 binding protein beta" P20851 1 207088860-207099993 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 471.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 597.6" "Cancer enriched" "Detected in many" 19 "liver cancer: 83.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 16 "CACO-2: 116.4;HeLa: 46.2;Hep G2: 151.6;OE19: 57.1" "Not detected" "Not detected" "HPA000925, HPA051620" Approved Uncertain "Golgi apparatus" "Secreted to blood" NA NA 265000000000 1100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "HPA000925: , HPA051620: AB_2681554" "unprognostic (1.73e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-1)" "unprognostic (2.07e-3)" "unprognostic (1.72e-1)" "unprognostic (2.54e-2)" "unprognostic (4.58e-3)" "unprognostic (9.49e-2)" "unprognostic (1.37e-1)" "unprognostic (4.25e-1)" "unprognostic (6.39e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (8.25e-2)" 3.0 0.1 0.0 3.4 0.0 0.0 1.8 0.0 0.1 2.8 0.0 3.6 3.8 0.1 0.0 0.2 0.5 3.1 0.1 0.0 0.0 0.4 471.3 1.5 0.4 0.0 0.0 44.2 9.1 0.0 0.0 6.2 0.1 0.0 1.8 0.0 0.5 0.0 0.1 0.2 4.4 0.6 0.0 0.4 8.4 0.7 0.0 0.1 0.0 0.1 0.2 0.4 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.4 5.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 46.2 151.6 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.6 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 12.8 2.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 7.3 2.2 0.5 54.3 3.2 0.0 0.0 1.0 0.2 10.2 1.9 11.4 4.1 0.7 0.1 0.8 1.8 8.0 0.1 88.8 0.3 3.4 5.6 0.8 0.0 0.3 9.7 597.6 2.1 0.0 0.2 5.6 0.0 13.1 0.3 2.8 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 69.2 15.9 0.0 0.1 0.2 4.3 0.0 2.2 0.0 0.0 1.1 0.4 0.1 0.4 0.0 0.0 0.1 1.1 143.8 4.8 0.1 C4orf48 ENSG00000243449 "Chromosome 4 open reading frame 48" Q5BLP8 4 2041993-2043970 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.9;choroid plexus: 62.6;pituitary gland: 74.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 412.4;Paneth cells: 484.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 158.3;NB-4: 117.3;PC-3: 343.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052447 Uncertain Approved Cytosol "Secreted to blood" NA NA 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA052447: AB_2681837" "unprognostic (7.96e-2)" "unprognostic (2.57e-3)" "unprognostic (2.08e-1)" "unprognostic (3.20e-2)" "unprognostic (4.01e-2)" "unprognostic (8.26e-2)" "unprognostic (4.85e-3)" "unprognostic (2.51e-3)" "unprognostic (2.28e-3)" "unprognostic (1.80e-1)" "unprognostic (1.95e-2)" "unprognostic (5.55e-2)" "unprognostic (3.42e-2)" "unprognostic (5.38e-3)" "unprognostic (2.68e-1)" "unprognostic (5.55e-2)" "unprognostic (3.17e-3)" 13.5 18.3 50.0 4.6 68.4 2.7 9.6 71.0 66.6 5.2 62.6 20.4 2.7 5.5 0.2 4.3 7.8 0.4 8.2 49.4 60.8 20.2 4.0 7.9 1.3 81.5 63.2 6.6 18.9 2.4 74.5 2.1 58.6 7.1 0.9 0.2 9.2 1.4 1.2 3.1 16.3 0.6 67.8 18.5 11.9 56.1 60.3 0.3 9.3 0.0 0.6 6.8 2.9 97.9 33.4 27.1 5.3 24.9 2.4 3.9 35.3 31.2 6.0 5.6 5.3 18.6 19.6 4.4 29.2 1.2 10.4 9.2 0.6 3.5 1.7 20.1 158.3 10.5 15.8 10.7 5.2 21.7 70.3 3.0 5.9 1.2 0.0 1.8 5.9 17.9 35.1 0.1 3.9 20.6 24.6 117.3 15.8 1.8 343.1 56.1 8.3 11.2 5.0 12.3 42.7 60.0 15.3 0.7 47.7 0.5 8.3 10.3 26.5 14.7 31.9 11.0 35.3 23.8 22.4 0.4 14.6 13.2 20.8 88.5 451.6 431.5 123.6 325.6 127.5 187.7 157.2 138.3 270.0 167.9 89.1 92.9 349.2 29.6 290.7 301.1 199.8 192.8 50.0 68.4 71.0 66.6 49.4 60.8 81.5 63.2 58.6 67.8 60.3 97.9 13.3 0.0 1.9 8.8 58.1 21.9 6.6 13.2 7.4 12.0 147.0 139.8 10.6 20.0 14.2 200.5 0.0 8.0 52.8 412.4 70.5 320.8 97.1 326.7 92.6 42.1 235.1 30.7 5.6 222.7 116.5 47.7 35.7 107.3 107.5 209.0 123.1 11.9 235.5 18.5 8.2 154.2 44.7 272.1 113.3 350.5 19.3 158.9 327.3 7.5 205.2 78.8 20.6 6.0 41.1 198.2 484.2 28.2 84.1 10.9 223.7 7.9 28.8 15.0 13.1 1.7 53.2 99.7 193.2 5.7 10.1 13.1 73.9 50.9 117.1 11.1 C5 "C5a, C5b, CPAMD4" ENSG00000106804 "Complement C5" P01031 9 120952335-121050275 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Inflammatory response, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 433.7" "Cell type enriched" "Detected in many" 16 "Hepatocytes: 538.3" "Cancer enriched" "Detected in many" 17 "liver cancer: 73.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 28.4;Hep G2: 30.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029339 Supported "Secreted to blood" NA NA 113000000000 39000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA029339: AB_10601125" "unprognostic (2.51e-1)" "unprognostic (5.88e-3)" "unprognostic (2.50e-3)" "unprognostic (1.57e-2)" "unprognostic (5.05e-2)" "unprognostic (9.52e-3)" "prognostic favorable (9.43e-4)" "unprognostic (1.83e-1)" "unprognostic (3.19e-2)" "unprognostic (1.55e-1)" "unprognostic (2.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.46e-5)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (3.67e-2)" "unprognostic (2.75e-1)" 2.9 1.7 2.5 1.1 3.4 2.2 2.5 2.4 2.6 3.0 3.5 2.8 3.9 2.7 2.7 1.6 3.0 1.5 1.3 2.2 2.6 4.8 433.7 7.0 2.1 2.9 2.9 3.3 14.9 2.6 3.1 0.9 3.2 3.2 1.6 3.5 1.4 2.2 0.5 3.8 3.9 1.9 2.8 1.5 5.8 1.6 2.8 1.2 2.0 1.2 1.7 2.6 2.1 4.5 1.6 28.4 6.4 11.3 8.0 9.2 0.2 3.4 3.5 0.9 2.0 0.8 2.8 4.1 0.1 1.8 3.8 11.0 0.3 0.3 1.5 0.9 0.0 1.8 1.5 30.4 1.5 1.0 0.7 4.1 0.5 2.0 3.7 1.8 1.0 1.6 0.7 3.8 2.2 5.6 0.4 0.2 1.7 7.0 10.9 2.5 2.8 0.4 1.7 0.8 1.6 6.5 1.6 0.0 2.7 4.4 2.2 3.7 1.3 2.8 0.2 7.5 3.4 2.3 1.8 1.7 2.2 3.8 6.8 0.0 0.3 0.4 0.0 0.0 0.2 0.3 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 3.4 2.4 2.6 2.2 2.6 2.9 2.9 3.2 2.8 2.8 4.5 0.8 6.4 28.6 30.0 3.5 1.0 1.0 0.5 1.8 4.8 2.2 1.3 0.8 32.9 7.1 1.8 0.0 0.1 0.1 0.4 1.9 0.2 1.8 1.1 2.2 1.4 0.0 12.0 7.3 0.4 0.0 2.9 2.0 0.8 0.0 3.1 7.5 538.3 1.9 6.7 9.4 1.0 0.0 16.3 1.0 2.8 3.1 3.5 0.0 6.5 2.3 3.2 2.1 25.6 25.4 0.7 3.8 9.1 0.1 0.7 1.0 6.8 3.8 2.6 0.0 4.0 1.6 7.5 2.5 2.0 1.3 0.0 1.4 2.8 2.0 0.6 C5orf46 "MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 181.8;skin 1: 113.1" "Group enriched" "Detected in some" 12 "Early spermatids: 320.9;Late spermatids: 189.9" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Region enriched" "Detected in single" 10 "cerebellum: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 54.2;PC-3: 90.8;SiHa: 20.2;U-2 OS: 58.2;U-251 MG: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" NA NA 54000 "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 13.5 2.3 0.1 1.6 0.7 0.4 0.0 0.1 0.4 0.4 0.0 0.2 9.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.2 0.9 0.0 0.6 181.8 0.1 0.8 113.1 0.0 3.2 0.0 0.0 0.0 19.2 0.0 0.3 0.2 0.1 0.3 0.0 3.6 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 2.4 1.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.6 0.0 0.2 0.2 0.0 4.6 0.2 0.0 0.0 0.0 0.0 1.1 0.0 8.9 54.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 20.2 0.3 0.3 11.1 0.0 0.0 0.0 10.0 58.2 0.8 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 9.2 3.7 11.0 15.7 0.2 1.8 0.0 0.5 0.2 0.0 0.0 15.9 320.9 0.7 0.4 0.3 0.0 0.0 0.0 3.3 0.6 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 189.9 1.8 0.2 3.6 0.0 0.6 7.7 0.0 0.0 0.0 4.2 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 1.1 0.8 0.0 20.6 1.4 0.1 0.0 0.0 0.2 C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 665.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 127.2;Hepatocytes: 376.9;Late spermatids: 54.8;Leydig cells: 120.2;Respiratory ciliated cells: 58.0" "Group enriched" "Detected in many" 7 "liver cancer: 49.0;pancreatic cancer: 12.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 4.5;ASC TERT1: 6.2;HSkMC: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043823, CAB069427" Enhanced "Secreted to blood" NA NA 45000000000 9200000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB069427: AB_1614336, HPA043823: AB_10960262" "unprognostic (9.79e-2)" "unprognostic (1.96e-2)" "unprognostic (5.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (4.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (3.04e-3)" "prognostic favorable (4.31e-4)" "unprognostic (2.69e-4)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" 12.8 1.1 0.2 0.0 0.2 0.0 5.4 0.2 0.1 0.8 1.6 0.8 0.9 0.4 0.9 0.3 43.9 12.0 57.1 0.2 0.6 4.4 665.9 3.2 0.4 0.0 1.7 6.2 42.7 0.1 0.7 2.8 0.2 0.9 0.6 0.0 0.9 0.6 0.6 0.6 1.4 0.9 0.1 0.3 2.2 4.2 0.8 0.6 2.0 0.7 0.5 0.9 0.6 0.6 0.0 0.0 0.0 0.0 4.5 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.2 0.6 0.0 1.7 0.2 0.1 0.8 0.6 0.8 0.0 0.0 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 20.9 127.2 7.5 0.0 0.0 0.0 0.1 0.3 0.0 9.3 11.3 37.5 0.8 0.9 0.0 8.0 1.4 0.4 0.0 6.7 0.0 0.7 0.0 0.1 5.0 376.9 0.0 0.0 2.7 1.0 0.0 9.7 0.3 54.8 120.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.5 1.3 0.4 0.0 0.0 11.6 0.8 58.0 0.0 0.0 0.2 0.4 0.4 0.1 0.0 0.0 0.0 0.4 0.5 0.6 0.0 C6orf120 bA160E12.4 ENSG00000185127 "Chromosome 6 open reading frame 120" Q7Z4R8 6 169702190-169704856 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 116.9;Late spermatids: 272.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039626 Uncertain "Secreted to blood" NA NA 620000 "Cluster 26: Non-specific - Mitochondria" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "HPA039626: AB_10673361" "unprognostic (2.98e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (3.43e-2)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (9.52e-5)" "unprognostic (1.78e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" "unprognostic (1.63e-1)" "unprognostic (6.21e-3)" "unprognostic (2.88e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-3)" 21.6 16.6 10.2 14.5 10.7 7.7 15.2 10.8 11.5 13.1 9.8 15.5 16.3 11.2 9.3 13.4 10.3 13.1 9.6 10.6 10.6 19.3 28.0 10.6 16.4 8.8 10.8 15.6 14.2 12.0 6.1 20.0 9.5 12.0 14.4 26.3 13.7 12.0 13.8 9.0 15.9 13.4 10.7 13.7 14.8 8.7 11.2 12.4 10.4 13.2 15.5 15.2 6.7 12.2 13.9 10.9 26.2 40.1 71.4 59.3 29.6 28.5 40.9 23.3 27.2 14.9 12.7 11.8 22.4 35.0 38.7 20.8 17.2 26.1 38.9 20.0 41.6 16.8 10.5 31.4 50.6 28.2 25.7 73.2 21.0 27.8 32.0 40.8 28.6 26.7 45.0 32.8 40.6 25.1 15.3 19.3 22.4 24.3 12.7 11.1 14.4 32.0 28.9 15.3 10.6 24.0 23.7 14.9 19.6 29.7 24.9 36.7 31.8 9.8 19.2 52.3 19.6 42.2 69.3 16.7 32.5 25.7 26.3 6.2 7.9 7.1 3.2 7.6 4.3 3.2 4.7 5.6 6.3 4.9 6.2 5.2 4.2 3.1 6.0 2.1 3.4 3.9 10.2 10.7 10.8 11.5 10.6 10.6 8.8 10.8 9.5 10.7 11.2 12.2 11.3 16.0 5.3 7.2 14.1 9.8 12.6 9.9 12.0 15.3 12.5 9.4 8.8 5.7 10.3 14.7 25.0 27.5 13.2 20.2 9.8 10.6 116.9 9.7 18.5 9.7 14.3 18.3 9.5 15.8 31.6 19.5 16.3 10.8 9.5 11.3 8.9 18.9 16.6 8.4 12.9 12.7 14.2 16.9 6.5 272.5 17.7 13.6 19.6 1.9 15.2 28.6 10.3 11.1 10.3 10.9 10.3 11.7 18.8 13.1 22.4 12.7 12.4 24.6 0.0 10.3 10.8 15.4 12.3 12.6 10.2 29.0 10.9 9.2 12.9 14.7 C6orf15 STG ENSG00000204542 "Chromosome 6 open reading frame 15" Q6UXA7 6 31111223-31112575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 5.5;lymphoid tissue: 3.5;skin 1: 6.7" "Cell type enriched" "Detected in some" 14 "Breast glandular cells: 73.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "RH-30: 13.4;U-2 OS: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA001436 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 30: Mammary glandular cells - Lactation" "HPA001436: AB_2243752" "unprognostic (2.73e-2)" "unprognostic (5.39e-2)" "unprognostic (1.46e-2)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.35e-1)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 3.5 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.0 1.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 C6orf58 LEG1 ENSG00000184530 "Chromosome 6 open reading frame 58" Q6P5S2 6 127519455-127591820 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 612.7;salivary gland: 2257.3" "Group enriched" "Detected in some" 12 "Early spermatids: 14.3;Gastric mucus-secreting cells: 41.3" "Group enriched" "Detected in some" 6 "pancreatic cancer: 17.1;stomach cancer: 14.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 2.0;RPMI-8226: 2.8;WM-115: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036263, HPA041449" Enhanced "Secreted to digestive system" NA NA 30000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA036263: AB_10673349, HPA041449: AB_2677486" "unprognostic (1.49e-1)" "unprognostic (8.55e-2)" "unprognostic (2.71e-1)" "unprognostic (5.69e-2)" "unprognostic (3.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (3.26e-2)" "unprognostic (7.72e-3)" "unprognostic (1.69e-1)" "unprognostic (6.62e-4)" "unprognostic (2.10e-2)" "unprognostic (2.31e-1)" "unprognostic (1.53e-2)" "unprognostic (8.99e-3)" 0.1 0.6 0.0 0.0 0.4 0.0 0.3 0.0 0.3 0.1 0.1 0.1 612.7 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 2257.3 0.0 0.2 0.0 0.2 0.1 0.0 0.3 268.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.2 2.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 2.8 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 14.3 0.1 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.2 41.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 2.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.8 0.7 0.0 0.1 0.3 0.0 0.2 0.0 0.3 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 C8A ENSG00000157131 "Complement C8 alpha chain" P07357 1 56854797-56918223 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 195 "liver: 635.7" "Cell type enriched" "Detected in some" 36 "Hepatocytes: 296.4" "Cancer enriched" "Detected in single" 279 "liver cancer: 85.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Hep G2: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 6400000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (3.73e-3)" "unprognostic (2.44e-1)" "unprognostic (1.28e-1)" "unprognostic (6.40e-2)" "unprognostic (9.82e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.1 635.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.0 5.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 296.4 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 C8B ENSG00000021852 "Complement C8 beta chain" P07358 1 56929207-56966140 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 156 "liver: 840.0" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 295.1" "Cancer enriched" "Detected in some" 181 "liver cancer: 107.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 22 "basophil: 2.1" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023694 Supported "Secreted to blood" NA NA 6700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA023694: AB_1847128" "unprognostic (6.65e-2)" "prognostic favorable (9.31e-5)" "unprognostic (2.37e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-2)" "unprognostic (6.57e-2)" "unprognostic (5.12e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 840.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.2 1.0 0.0 0.1 0.0 5.3 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 7.1 295.1 0.1 0.0 0.1 0.0 0.0 7.6 0.0 11.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 C8G ENSG00000176919 "Complement C8 gamma chain" P07360 9 136945185-136946975 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 564.4" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1134.7" "Cancer enriched" "Detected in all" 58 "liver cancer: 260.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HMC-1: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA046269 Approved "Secreted to blood" NA NA 2800000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "HPA046269: AB_2679606" "unprognostic (5.00e-2)" "unprognostic (4.05e-3)" "prognostic unfavorable (2.99e-4)" "unprognostic (3.94e-1)" "unprognostic (4.53e-1)" "unprognostic (2.75e-2)" "unprognostic (1.71e-3)" "unprognostic (2.79e-1)" "unprognostic (1.88e-1)" "unprognostic (3.67e-1)" "unprognostic (2.96e-2)" "unprognostic (3.00e-1)" "unprognostic (5.02e-3)" "unprognostic (2.16e-1)" "unprognostic (7.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" 0.3 1.5 0.1 0.0 0.1 0.0 0.3 0.1 0.3 0.3 0.0 1.2 31.2 0.4 0.9 0.5 0.4 2.5 1.3 0.1 0.1 2.3 564.4 0.3 0.1 0.1 0.1 0.1 0.3 0.0 0.6 0.0 0.2 0.4 0.3 0.0 0.4 0.1 3.1 0.3 17.8 0.0 0.1 2.1 1.3 2.3 0.1 0.2 0.7 0.0 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.4 0.0 0.0 41.8 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 1.0 0.0 0.0 0.3 2.3 0.4 0.2 0.4 0.0 0.0 0.4 0.9 0.7 28.6 0.3 0.0 2.1 0.4 1.1 25.0 0.0 0.2 0.9 0.1 0.1 0.7 1.8 8.0 0.2 0.8 1.0 0.1 0.0 0.3 8.9 1.2 17.5 1134.7 0.3 0.0 0.2 5.0 0.0 25.3 0.2 1.5 0.0 0.2 0.0 0.0 0.0 1.1 4.1 0.5 0.1 0.5 4.7 0.7 0.0 0.4 122.3 6.7 0.1 0.5 0.0 0.3 0.3 0.7 0.6 0.5 0.4 3.4 1.8 0.2 2.0 0.2 C9 ENSG00000113600 "Complement C9" P02748 5 39284140-39424868 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 288 "liver: 1397.0" "Cell type enriched" "Detected in some" 37 "Hepatocytes: 1962.3" "Cancer enriched" "Detected in single" 244 "liver cancer: 90.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "JURKAT: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002151, HPA029577" Uncertain "Secreted to blood" NA NA 69600000000 64000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB002151: AB_563670, HPA029577: AB_10603779" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (1.50e-1)" "unprognostic (2.01e-1)" "unprognostic (6.58e-2)" "unprognostic (1.30e-1)" "unprognostic (2.91e-1)" "unprognostic (5.49e-3)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (2.19e-2)" "unprognostic (9.43e-5)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.04e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1397.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 20.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.8 2.0 0.0 18.7 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 42.5 1962.3 1.2 0.0 0.1 0.2 0.0 52.6 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.1 3.7 1.7 0.0 0.0 0.3 3.0 0.0 0.0 0.1 CA10 "CA-RPX, CARPX, HUCEP-15" ENSG00000154975 "Carbonic anhydrase 10" Q9NS85 17 51630313-52160017 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.9;cervix: 21.8;retina: 44.5" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 1607.5" "Cancer enriched" "Detected in some" 4 "glioma: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.2;RT4: 2.1;SCLC-21H: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054825, HPA057837" Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA054825: AB_2682617, HPA057837: AB_2683542" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" "unprognostic (3.43e-1)" "unprognostic (8.22e-2)" "unprognostic (4.43e-3)" "unprognostic (1.02e-3)" "unprognostic (1.01e-1)" "unprognostic (5.91e-2)" "unprognostic (1.46e-1)" "unprognostic (7.21e-3)" "unprognostic (9.18e-5)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" 0.0 3.2 22.9 0.0 21.0 0.0 0.0 54.9 27.2 21.8 7.9 0.4 0.3 0.2 0.0 0.0 0.4 0.1 0.0 23.0 20.6 7.2 0.0 0.0 0.0 33.4 19.3 1.9 0.2 0.0 3.9 1.0 33.4 0.0 0.1 44.5 1.2 0.0 0.0 0.0 0.5 0.1 19.5 0.0 0.1 10.2 30.6 0.0 0.0 0.0 0.0 0.1 0.1 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.2 2.1 6.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 21.0 54.9 27.2 23.0 20.6 33.4 19.3 33.4 19.5 30.6 17.6 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.0 0.0 211.9 0.0 0.0 0.4 0.0 0.0 3.7 4.2 0.0 0.1 0.0 15.6 0.0 134.5 0.0 0.0 0.3 0.0 0.0 343.6 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 17.0 0.0 0.0 0.0 0.2 84.4 1.2 0.1 0.0 14.0 0.0 5.1 0.0 1607.5 4.2 0.0 0.0 0.7 0.1 0.2 0.0 0.2 0.0 11.9 0.0 0.1 0.0 1.5 1.3 0.0 0.0 0.1 2.2 0.0 0.0 0.1 CA11 "CARP2, CARPX1" ENSG00000063180 "Carbonic anhydrase 11" O75493 19 48637946-48646187 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 330.0;choroid plexus: 146.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 46.1;hTERT-RPE1: 47.1;SCLC-21H: 32.6;U-266/84: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041778 Approved Vesicles,Microtubules "Secreted in brain" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Microtubules" "HPA041778: AB_10794525" "unprognostic (1.39e-1)" "prognostic favorable (4.33e-4)" "unprognostic (2.59e-3)" "unprognostic (5.72e-2)" "unprognostic (1.54e-1)" "unprognostic (9.80e-3)" "unprognostic (6.02e-2)" "prognostic favorable (2.11e-5)" "unprognostic (3.79e-2)" "unprognostic (2.98e-1)" "prognostic favorable (8.60e-5)" "unprognostic (4.88e-2)" "unprognostic (8.64e-3)" "unprognostic (1.21e-1)" "unprognostic (7.15e-2)" "unprognostic (4.09e-3)" "unprognostic (1.75e-1)" 13.1 17.3 240.8 3.2 256.9 1.6 8.5 215.4 330.0 15.9 146.2 19.4 8.4 33.0 28.2 8.0 21.4 5.5 10.7 266.6 167.0 14.7 1.7 5.8 5.0 170.3 169.2 48.8 5.9 58.0 37.2 1.1 172.2 14.0 2.5 30.0 8.9 13.5 9.2 14.3 9.3 18.2 163.8 6.1 13.0 6.4 180.5 6.6 12.1 7.4 5.3 9.2 12.2 231.9 2.0 12.7 22.9 46.1 3.1 1.2 0.6 1.5 14.9 1.5 3.3 3.1 15.7 7.5 1.7 1.7 4.2 4.9 9.4 4.6 1.3 1.6 13.5 3.3 7.2 0.2 3.0 0.3 9.8 5.4 9.2 1.4 2.0 47.1 1.8 19.8 6.1 20.5 0.7 5.0 4.1 1.4 9.9 7.5 4.7 2.6 0.9 16.1 10.1 0.4 32.6 18.2 1.7 1.6 2.7 6.1 6.3 0.8 0.2 3.9 14.2 0.1 0.4 18.9 33.9 1.3 5.7 4.3 2.0 0.0 0.4 0.0 1.5 0.5 1.5 1.0 1.2 1.2 0.7 1.3 1.5 1.3 0.0 1.3 0.0 1.9 1.5 0.7 240.8 256.9 215.4 330.0 266.6 167.0 170.3 169.2 172.2 163.8 180.5 231.9 5.1 3.2 8.1 11.1 9.3 7.1 9.1 13.2 12.5 81.0 15.5 12.1 5.4 21.5 9.6 31.3 16.7 0.7 9.8 3.9 25.4 11.5 15.0 6.7 6.3 6.7 13.1 3.6 47.0 10.0 0.4 11.6 5.6 7.9 6.3 3.1 8.9 47.5 6.0 28.6 18.1 6.4 16.2 20.4 26.4 7.9 22.1 6.8 8.8 5.6 5.6 50.4 12.3 7.1 6.8 3.4 2.9 26.7 4.3 4.3 20.7 38.7 7.5 30.8 6.6 4.2 8.9 1.3 4.9 5.9 10.9 0.4 6.9 8.7 5.2 6.4 CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 295 "salivary gland: 9393.1" "Group enriched" "Detected in some" 44 "Breast glandular cells: 77.9;Ionocytes: 99.7;Melanocytes: 179.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.6;naive CD8 T-cell: 16.4" "Lineage enriched" "Detected in many" 11 "T-cells: 16.4" "Cell line enhanced" "Detected in some" "Daudi: 1.7;U-2197: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" NA NA 24000000 "Cluster 32: T-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" 0.4 0.4 0.3 0.7 0.6 2.0 20.8 0.9 0.7 0.0 0.5 0.1 0.3 0.2 2.3 0.2 0.1 0.2 1.5 0.4 0.3 0.1 0.1 0.3 1.3 0.9 0.4 1.9 6.3 0.0 0.1 0.9 0.7 0.2 0.2 0.7 9393.1 0.0 0.4 31.8 0.5 0.0 0.1 1.2 0.4 0.3 0.7 1.2 0.3 0.0 1.0 0.1 0.0 1.8 0.2 0.0 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.3 0.4 1.7 0.1 0.1 0.4 0.3 0.1 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.0 0.5 0.5 0.0 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.4 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.3 0.2 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.6 0.3 1.3 0.2 0.4 0.1 0.4 0.1 0.4 0.4 1.4 0.3 0.2 0.3 0.2 0.3 0.3 0.7 2.7 0.0 0.5 5.6 16.4 1.3 0.4 0.2 0.3 0.3 1.6 0.3 0.6 0.9 0.7 0.4 0.3 0.9 0.4 0.7 0.1 0.7 1.8 0.2 0.0 0.0 0.0 0.1 0.1 0.1 1.4 0.0 0.0 77.9 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 99.7 0.0 1.3 0.2 0.0 0.2 179.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.6 0.5 0.0 0.0 CALCA "CALC1, CGRP, CGRP-alpha" ENSG00000110680 "Calcitonin related polypeptide alpha" "P01258, P06881" 11 14966668-14972351 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, Transporters" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 178.3;thyroid gland: 154.2" "Cell type enriched" "Detected in some" 64 "Ionocytes: 2368.1" "Cancer enriched" "Detected in many" 7 "lung cancer: 64.7" "Region enhanced" "Detected in many" "pons: 34.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "pons and medulla: 57.9" "HPA059886, HPA064453" Enhanced Supported "Secreted to blood" NA NA 51500 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA059886: , HPA064453: " "unprognostic (1.97e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (5.99e-2)" "unprognostic (2.42e-1)" "unprognostic (1.17e-1)" "unprognostic (6.45e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (3.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.74e-2)" "unprognostic (2.53e-3)" "unprognostic (1.02e-2)" 0.7 0.2 0.6 1.5 0.6 0.0 0.2 0.6 0.5 0.2 0.0 0.6 0.0 0.2 0.0 0.1 0.3 0.2 1.1 0.3 0.8 46.4 37.5 2.4 0.1 20.9 7.0 0.1 0.4 178.3 0.8 0.0 34.4 2.5 0.1 0.0 0.1 0.0 0.5 0.0 0.1 1.5 1.5 3.0 0.2 0.2 0.6 0.3 154.2 0.0 0.0 4.3 0.4 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.5 0.3 0.8 20.9 7.0 34.4 1.5 0.6 10.4 0.1 0.0 0.0 0.0 0.2 0.3 0.4 35.4 0.0 0.0 0.0 0.1 0.4 0.0 0.3 36.8 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.3 0.0 0.0 0.7 4.4 0.3 0.0 0.0 0.0 2368.1 0.0 4.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.2 0.0 0.0 0.4 5.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 CALCB "CALC2, CGRP-II, FLJ30166" ENSG00000175868 "Calcitonin related polypeptide beta" P10092 11 14904997-15082342 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 18.9;thyroid gland: 20.7" "Group enriched" "Detected in some" 4 "Melanocytes: 5.4;Spermatogonia: 5.1" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;endometrial cancer: 2.4;thyroid cancer: 0.9" "Group enriched" "Detected in many" 4 "hypothalamus: 6.8;medulla oblongata: 8.9;midbrain: 11.6;pons: 18.9;white matter: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 5.8;Karpas-707: 10.4;SH-SY5Y: 3.5;U-266/70: 16.0" "Region enriched" "Detected in some" 7 "pons and medulla: 9.6" "Group enriched" "Detected in many" 5 "amygdala: 30.4;basal ganglia: 74.3;hypothalamus: 50.1;midbrain: 33.9;pons: 41.7" HPA059886 Supported "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA059886: " "unprognostic (7.84e-2)" "unprognostic (4.07e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (3.42e-5)" "unprognostic (2.02e-1)" "unprognostic (8.40e-2)" "unprognostic (1.75e-1)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "unprognostic (3.32e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-1)" "unprognostic (1.02e-2)" "unprognostic (2.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" 0.3 0.0 0.1 0.3 0.2 0.0 0.2 0.5 0.6 0.2 0.1 1.4 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.3 6.8 1.0 0.8 0.1 0.1 8.9 11.6 0.1 1.5 0.3 2.2 0.1 18.9 0.1 0.2 0.1 0.3 0.0 0.8 0.1 0.4 0.1 2.3 0.1 0.1 0.3 1.0 0.0 20.7 0.1 0.1 0.0 0.1 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.2 5.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 1.9 0.0 0.4 0.1 0.0 10.4 0.0 0.0 0.0 0.6 2.9 0.1 0.1 0.4 0.0 0.2 0.0 0.0 1.1 3.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 16.0 0.6 0.4 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.6 0.3 6.8 8.9 11.6 18.9 2.3 1.0 4.7 0.0 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.0 0.0 0.6 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.1 0.4 0.0 0.0 0.4 0.2 0.9 0.5 0.2 0.5 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.3 0.0 0.0 5.4 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.9 5.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 CAMP "CAP18, FALL-39, FALL39, LL37" ENSG00000164047 "Cathelicidin antimicrobial peptide" P49913 3 48223347-48225491 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 2914.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.3;Fibroblasts: 6.9;Late spermatids: 17.4;Prostatic glandular cells: 9.4;Spermatocytes: 5.0;Spermatogonia: 7.2" "Cancer enriched" "Detected in many" 4 "testis cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "eosinophil: 84.4;neutrophil: 335.4" "Lineage enriched" "Detected in many" 12 "granulocytes: 335.4" "Cell line enhanced" "Detected in some" "Daudi: 27.3;hTCEpi: 19.0;U-698: 77.5" "Not detected" "Not detected" "CAB015949, CAB016522, HPA029874" Enhanced "Secreted to blood" NA NA 617000000 28000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "CAB015949: , CAB016522: , HPA029874: AB_10600859" "unprognostic (2.14e-2)" "prognostic favorable (5.73e-4)" "unprognostic (4.59e-2)" "unprognostic (2.62e-1)" "unprognostic (9.41e-2)" "unprognostic (4.57e-5)" "unprognostic (3.09e-1)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (7.65e-2)" "unprognostic (1.32e-1)" "unprognostic (8.08e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-1)" "unprognostic (1.71e-1)" "unprognostic (1.80e-2)" "unprognostic (1.03e-2)" 0.8 0.1 0.1 1.6 0.1 2914.5 0.5 0.1 0.5 0.6 0.1 0.3 0.0 0.6 339.9 0.4 0.1 0.3 1.4 0.1 0.1 0.4 3.9 7.4 6.8 0.2 0.1 0.2 0.1 0.1 0.5 2.4 0.2 0.5 0.1 0.0 15.2 0.6 0.2 3.7 1.7 0.1 0.1 23.2 0.4 1.9 0.1 10.7 5.7 0.2 2.9 0.4 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 27.3 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 19.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 1.0 1.4 0.1 0.0 3.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 77.5 0.0 3.4 0.1 37.9 5.5 84.4 0.0 9.8 0.0 2.3 0.0 0.0 7.7 2.4 0.0 0.0 335.4 2.6 28.1 4.7 0.0 86.9 0.1 0.1 0.1 0.5 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.2 0.0 0.9 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.3 0.9 0.3 0.2 0.0 2.1 0.0 0.2 0.0 6.9 0.5 1.4 0.0 0.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 1.3 1.1 17.4 0.9 3.6 1.8 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.8 9.4 0.0 0.1 0.7 0.0 0.0 0.0 0.1 5.0 7.2 0.0 0.0 0.0 1.0 0.0 0.4 0.6 CARTPT CART ENSG00000164326 "CART prepropeptide" Q16568 5 71719275-71721048 "FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 118.6;brain: 183.6" "Group enriched" "Detected in some" 5 "Bipolar cells: 47.4;Early spermatids: 25.4;Prostatic glandular cells: 39.5;Spermatocytes: 55.7" "Cancer enriched" "Detected in many" 9 "breast cancer: 117.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 209.0" "CAB025515, HPA046278, CAB079776" Enhanced Supported "Secreted to blood" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB025515: , CAB079776: , HPA046278: AB_10961570" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (3.45e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.14e-1)" 2.4 118.6 85.6 4.4 10.1 0.0 9.3 2.6 48.9 0.0 3.9 16.8 5.5 2.8 0.7 0.3 0.4 0.2 0.1 28.0 134.0 0.3 0.0 0.1 0.0 69.8 111.9 0.1 0.5 0.0 5.2 0.0 183.6 8.6 4.5 21.4 0.1 0.0 0.0 0.1 3.4 15.1 24.5 0.0 14.6 7.1 102.4 0.2 5.4 0.0 0.0 0.0 0.3 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.6 10.1 2.6 48.9 28.0 134.0 69.8 111.9 183.6 24.5 102.4 9.8 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 47.4 0.2 0.3 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 25.4 1.6 0.1 1.0 7.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 39.5 0.0 0.0 0.0 8.1 0.0 0.0 0.1 55.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 CATSPERG "C19orf15, DKFZp434A1022, FLJ46353" ENSG00000099338 "Cation channel sperm associated auxiliary subunit gamma" Q6ZRH7 19 38335775-38370943 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 31.3" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Gastric mucus-secreting cells: 27.0;Late spermatids: 49.2;Proximal enterocytes: 20.7;Spermatocytes: 28.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 1.4;HMC-1: 1.8;MCF7: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052777 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in male reproductive system" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" Nucleoli "Nucleoplasm, Cytosol" "HPA052777: " "unprognostic (8.50e-5)" "unprognostic (5.12e-2)" "unprognostic (3.57e-3)" "unprognostic (1.51e-1)" "unprognostic (2.63e-1)" "unprognostic (3.18e-1)" "unprognostic (2.60e-1)" "unprognostic (2.87e-3)" "unprognostic (1.00e-1)" "unprognostic (2.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (4.37e-4)" "unprognostic (9.99e-2)" "unprognostic (2.01e-1)" "unprognostic (4.61e-2)" "unprognostic (1.07e-3)" 0.2 0.1 0.5 0.1 0.8 0.3 0.4 0.8 0.9 0.4 0.2 0.2 0.4 0.2 0.7 0.2 0.5 0.1 0.1 0.4 0.5 0.2 0.2 0.3 0.3 0.7 2.8 0.4 0.2 0.2 0.2 0.1 0.7 0.4 0.2 0.2 0.3 0.2 0.2 1.0 0.3 0.1 0.4 0.2 0.2 31.3 0.8 0.2 0.5 0.0 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.6 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.3 0.0 0.1 0.2 0.0 0.3 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.7 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.5 0.0 0.7 0.1 0.1 0.0 0.5 0.8 0.8 0.9 0.4 0.5 0.7 2.8 0.7 0.4 0.8 1.1 4.9 0.0 2.7 2.6 3.6 2.5 2.4 1.0 4.6 1.3 4.8 8.0 3.0 1.5 0.6 1.8 0.0 1.7 5.1 10.1 0.0 1.0 29.4 4.9 4.4 2.7 1.8 3.2 4.3 0.7 0.3 3.0 27.0 8.8 1.3 2.0 2.5 0.3 3.2 1.7 3.8 3.9 2.0 1.2 3.1 49.2 1.8 3.3 0.0 1.9 3.9 1.9 10.3 3.0 17.0 0.4 5.6 2.2 2.2 1.9 20.7 0.9 1.3 1.4 0.0 5.3 3.7 28.9 3.7 4.9 1.8 1.4 3.4 1.9 3.5 1.8 CBLIF "GIF, IF, IFMH, INF, TCN3" ENSG00000134812 "Cobalamin binding intrinsic factor" P27352 11 59829273-59845499 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1859 "stomach 1: 1575.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "stomach cancer: 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039908, HPA040774" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "HPA039908: AB_10796335, HPA040774: AB_10795626" "unprognostic (2.78e-4)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (3.59e-1)" "unprognostic (1.66e-1)" 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.6 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1575.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 114.2;testis: 31.9" "Cell type enhanced" "Detected in some" "Early spermatids: 100.9;Late spermatids: 291.0;Spermatocytes: 61.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "NTERA-2: 40.0;SCLC-21H: 126.0" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in many" 13 "cerebellum: 369.4" "Secreted in brain" NA NA 6000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" 11.8 1.0 4.6 0.2 3.2 0.0 3.8 114.2 7.1 2.1 0.9 0.7 1.0 5.8 0.4 1.0 1.3 7.5 4.6 2.4 23.4 0.2 1.0 0.1 0.8 10.7 18.4 1.3 2.8 0.2 4.2 0.0 12.7 0.5 0.7 3.5 0.6 0.6 0.9 0.8 1.3 1.7 4.8 0.1 0.7 31.9 27.0 0.2 2.3 1.7 2.8 1.4 0.5 5.4 0.0 0.0 0.6 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 2.7 2.6 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 126.0 3.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 114.2 7.1 2.4 23.4 10.7 18.4 12.7 4.8 27.0 5.4 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.3 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 100.9 0.1 2.4 6.7 13.2 0.0 0.6 0.4 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 4.7 0.5 0.0 0.0 0.0 291.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.2 0.0 0.4 0.0 0.1 0.3 0.0 0.0 1.8 26.3 0.1 19.2 61.7 5.8 0.0 0.1 0.0 0.0 8.8 0.2 0.0 CBLN2 ENSG00000141668 "Cerebellin 2 precursor" Q8IUK8 18 72536680-72638521 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 32.5" "Cell type enriched" "Detected in some" 13 "Excitatory neurons: 508.3" "Cancer enriched" "Detected in single" 7 "breast cancer: 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 54.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in brain" NA NA 1400000 "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.03e-2)" "unprognostic (3.52e-1)" "unprognostic (1.13e-3)" "unprognostic (9.09e-5)" "unprognostic (7.10e-2)" "unprognostic (6.27e-3)" "unprognostic (7.39e-2)" "unprognostic (2.17e-1)" "unprognostic (1.37e-4)" "unprognostic (5.01e-4)" "unprognostic (8.15e-2)" "unprognostic (6.07e-4)" "unprognostic (7.19e-2)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (4.93e-2)" 0.4 0.2 7.9 0.3 17.3 0.0 0.1 0.0 32.5 0.3 0.0 1.8 1.5 0.0 0.0 0.0 0.1 0.0 0.1 3.3 0.2 2.5 0.4 0.0 0.0 5.9 4.5 0.1 0.0 0.0 0.2 0.0 8.7 0.9 1.5 5.1 0.0 5.1 0.0 0.8 2.5 0.8 0.0 0.0 0.1 0.2 13.8 0.0 0.0 0.0 0.7 0.1 0.0 12.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 54.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 17.3 0.0 32.5 3.3 0.2 5.9 4.5 8.7 0.0 13.8 12.8 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.7 0.3 37.8 0.0 508.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.3 0.6 0.6 0.0 0.0 10.3 0.0 0.5 0.0 9.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 93.9" "Cell type enhanced" "Detected in some" "dendritic cells: 3.0;Theca cells: 5.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 11 "cerebellum: 93.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 13.4;HDLM-2: 17.2;HSkMC: 23.3;Karpas-707: 18.3;U-266/70: 12.8" "Region enriched" "Detected in many" 25 "cerebellum: 429.5" "Region enriched" "Detected in many" 42 "cerebellum: 446.5" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA041266: AB_10674430" "unprognostic (5.02e-2)" "unprognostic (3.26e-1)" "unprognostic (1.43e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.39e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (6.20e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (6.20e-6)" "unprognostic (2.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (9.02e-2)" 7.3 17.1 2.7 8.3 3.0 0.6 4.7 93.9 7.0 4.6 2.1 4.2 2.1 2.7 7.4 2.9 4.0 5.6 3.7 2.4 3.3 4.4 6.0 4.8 13.7 3.9 5.8 10.1 2.0 2.9 4.2 3.7 8.4 4.5 2.1 0.5 4.3 3.1 1.8 3.5 5.4 2.2 3.2 13.7 3.3 5.1 3.4 3.9 4.5 0.6 9.1 4.9 4.6 4.8 1.5 1.3 0.7 2.5 6.2 13.4 0.4 5.5 11.1 2.1 2.7 0.7 2.6 2.4 1.2 3.4 2.4 0.3 0.8 2.9 1.4 17.2 0.6 0.0 5.2 1.1 3.3 0.4 0.9 23.3 1.3 2.7 2.1 8.8 1.9 1.0 0.7 18.3 2.8 0.8 0.0 0.7 0.1 1.5 1.5 0.0 0.0 1.8 1.2 0.5 0.9 0.5 0.5 0.1 0.8 0.3 0.8 0.6 8.7 7.7 1.5 3.2 0.3 12.8 3.2 2.7 0.4 1.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.0 93.9 7.0 2.4 3.3 3.9 5.8 8.4 3.2 3.4 4.8 1.4 0.0 0.0 0.0 2.6 0.4 0.6 1.5 0.0 0.0 0.8 1.0 0.5 0.0 0.4 0.0 0.0 0.9 3.0 0.8 0.0 1.1 0.0 0.3 2.0 0.8 0.0 0.4 0.3 1.1 0.6 2.6 0.0 0.5 0.0 0.9 0.0 0.2 0.9 0.0 0.1 0.5 0.0 0.3 0.4 0.3 2.5 0.7 0.0 1.0 2.6 1.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 0.5 0.9 0.8 1.4 0.2 0.0 0.7 1.4 0.0 0.2 0.2 0.6 0.8 0.2 5.7 0.6 0.6 CBLN4 "CBLNL1, dJ885A10.1" ENSG00000054803 "Cerebellin 4 precursor" Q9NTU7 20 55997357-56005519 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.8;brain: 19.3;epididymis: 8.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 8.9;Excitatory neurons: 26.9;Inhibitory neurons: 31.6;Peritubular cells: 38.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 50 "SH-SY5Y: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074497 Supported "Secreted in brain" NA NA 10000000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074497: " "unprognostic (3.61e-1)" "unprognostic (8.43e-3)" "unprognostic (2.43e-1)" "unprognostic (1.61e-2)" "unprognostic (1.99e-1)" "unprognostic (4.00e-1)" "unprognostic (3.25e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (3.88e-1)" "unprognostic (9.63e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-3)" "unprognostic (3.22e-4)" "unprognostic (7.50e-2)" "unprognostic (3.58e-2)" "unprognostic (1.79e-3)" 1.6 17.8 14.6 0.1 3.4 0.0 1.4 0.0 9.4 1.9 0.0 0.0 0.0 0.7 8.8 0.1 3.8 0.5 0.0 14.4 5.8 0.6 0.9 0.7 0.0 0.7 19.3 2.0 0.7 0.3 0.1 0.2 2.4 0.1 0.0 0.3 0.1 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.3 2.0 12.2 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 3.4 0.0 9.4 14.4 5.8 0.7 19.3 2.4 0.0 12.2 0.2 0.1 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.2 8.9 0.0 26.9 0.0 0.0 5.2 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.7 31.6 0.0 0.0 0.0 0.0 1.0 2.1 0.2 0.0 1.9 0.0 0.2 0.0 1.0 2.0 0.0 0.0 38.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC126 FLJ23031 ENSG00000169193 "Coiled-coil domain containing 126" Q96EE4 7 23597382-23644708 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.6" "Group enriched" "Detected in all" 18 "Early spermatids: 642.3;Late spermatids: 490.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 479.0" "Lineage enriched" "Detected in all" 23 "granulocytes: 479.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010969, HPA026883" Uncertain Approved "Golgi apparatus" "Secreted to blood" NA NA 39000000 "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA010969: , HPA026883: AB_1846131" "unprognostic (2.02e-1)" "unprognostic (2.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (5.96e-3)" "unprognostic (1.16e-2)" "unprognostic (3.90e-1)" "unprognostic (9.30e-2)" "unprognostic (1.42e-2)" "unprognostic (3.44e-2)" "unprognostic (3.29e-2)" "unprognostic (7.35e-3)" "unprognostic (5.90e-2)" "unprognostic (1.20e-1)" "unprognostic (1.62e-1)" "unprognostic (3.28e-1)" 6.5 7.5 3.7 4.5 4.1 7.6 8.4 6.5 4.9 6.6 2.5 5.2 8.6 7.2 4.8 5.9 6.4 5.9 5.0 3.6 4.6 7.2 11.6 6.1 8.9 5.0 5.2 6.8 8.4 11.7 4.3 4.5 4.5 5.5 6.1 8.4 5.4 5.5 7.1 4.8 7.0 6.2 4.6 6.3 6.5 34.6 4.7 5.4 9.4 10.0 8.8 6.3 4.4 4.1 6.0 4.1 8.9 11.3 14.6 8.1 20.4 7.4 7.3 6.2 9.0 4.3 1.9 12.8 11.3 6.2 11.8 3.4 3.9 3.5 8.1 2.7 5.1 2.2 1.6 5.6 5.8 5.9 10.9 8.7 10.0 2.0 1.9 5.2 8.4 5.3 5.2 3.5 7.6 2.8 4.1 7.1 4.2 7.9 5.1 2.7 14.0 3.9 6.5 2.7 5.4 10.2 7.6 7.2 5.6 13.8 6.1 5.4 10.2 3.7 6.5 8.4 5.9 9.9 10.5 9.2 4.1 8.5 20.2 479.0 18.0 86.7 14.7 17.0 17.6 20.7 15.8 17.0 15.6 19.3 19.2 15.0 35.2 16.8 17.1 3.2 19.3 15.6 3.7 4.1 6.5 4.9 3.6 4.6 5.0 5.2 4.5 4.6 4.7 4.1 17.3 6.4 8.1 12.7 12.8 19.1 7.9 8.0 13.6 14.1 15.4 10.7 9.0 12.8 8.2 12.9 8.4 10.2 9.3 7.3 7.9 10.1 642.3 11.1 9.0 10.8 15.0 4.8 14.0 9.1 6.8 11.5 13.3 9.5 7.0 3.7 10.8 15.2 6.9 8.4 17.4 8.7 16.2 7.9 9.6 490.0 11.5 9.5 14.2 12.2 11.4 7.7 14.4 18.6 20.1 10.4 7.3 14.3 12.8 8.3 8.4 8.9 14.6 14.1 13.1 12.0 12.9 31.1 26.3 12.1 23.7 20.2 11.3 29.2 5.9 6.9 CCDC134 FLJ22349 ENSG00000100147 "Coiled-coil domain containing 134" Q9H6E4 22 41800679-41832164 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003936 Approved "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA003936: AB_1078419" "unprognostic (2.09e-2)" "unprognostic (1.00e-1)" "unprognostic (3.82e-2)" "prognostic favorable (4.09e-4)" "unprognostic (1.73e-1)" "unprognostic (3.85e-2)" "prognostic unfavorable (7.42e-7)" "unprognostic (4.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-2)" "unprognostic (7.32e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.24e-3)" "unprognostic (2.52e-2)" "unprognostic (5.47e-1)" "unprognostic (6.63e-2)" 1.4 10.2 2.2 3.7 2.5 12.6 2.7 9.0 2.4 2.0 2.3 2.6 3.3 1.8 10.5 2.7 3.6 1.3 2.1 2.0 1.9 2.8 2.7 2.4 4.0 3.3 2.7 2.1 3.7 5.0 1.6 2.7 2.8 2.5 2.8 5.8 4.3 2.6 2.8 4.6 3.6 1.8 1.8 2.9 4.2 6.1 3.8 3.7 2.5 2.3 4.6 1.6 1.4 3.5 8.6 6.4 7.3 11.0 4.4 1.3 5.9 7.1 3.8 9.4 11.2 9.7 5.4 8.6 12.1 5.0 7.2 9.5 7.7 5.6 7.0 7.5 11.2 7.5 19.4 7.1 2.3 10.8 8.7 2.2 2.5 11.6 2.5 4.3 4.4 7.5 4.5 16.1 6.1 5.8 7.0 7.3 4.9 11.5 5.4 12.6 11.6 11.0 7.7 7.1 3.6 3.2 13.8 10.3 5.3 4.1 12.6 5.5 3.6 7.5 11.6 4.5 12.0 18.3 11.9 6.8 7.2 6.6 12.2 1.1 3.3 6.9 4.1 5.1 2.9 3.8 2.6 3.5 1.5 2.5 4.7 3.3 1.9 3.6 5.2 1.6 5.2 2.2 2.2 2.5 9.0 2.4 2.0 1.9 3.3 2.7 2.8 1.8 3.8 3.5 1.0 3.2 2.0 6.8 2.5 0.3 1.5 2.4 0.6 1.1 2.1 1.5 0.8 2.8 1.5 3.7 2.1 4.0 3.0 3.3 0.0 5.0 0.8 3.5 1.3 1.7 0.0 2.5 6.0 1.9 18.2 1.7 3.6 2.5 0.0 2.1 0.4 1.6 4.3 0.0 6.4 2.0 0.0 1.0 0.7 0.9 0.6 1.7 1.8 10.3 4.1 0.7 2.1 9.0 5.8 2.6 1.9 0.4 7.9 1.8 3.5 1.4 2.6 2.3 0.0 1.7 2.1 3.7 1.3 1.8 0.0 2.9 2.1 3.3 3.1 1.6 CCDC3 DKFZp761F241 ENSG00000151468 "Coiled-coil domain containing 3" Q9BQI4 10 12896625-13099652 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 132.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 50.1;Excitatory neurons: 100.2;Inhibitory neurons: 41.3;Peritubular cells: 60.5;Smooth muscle cells: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 10.4;HAP1: 19.1;HDLM-2: 32.4;hTERT-RPE1: 14.8;U-2 OS: 20.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 20.8" HPA062425 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA062425: AB_2684759" "unprognostic (2.26e-1)" "unprognostic (6.65e-3)" "unprognostic (1.70e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (5.08e-2)" "unprognostic (3.11e-2)" "unprognostic (2.99e-2)" "unprognostic (5.56e-3)" "unprognostic (5.41e-2)" "unprognostic (4.25e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.54e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (3.88e-2)" 91.8 11.0 32.9 5.9 35.2 0.1 37.2 17.9 40.2 48.1 17.8 10.1 6.6 25.0 41.3 60.4 56.7 70.7 21.9 37.1 20.1 19.0 20.6 21.0 12.4 18.6 19.1 86.2 6.5 4.9 10.2 22.2 19.6 35.2 7.4 1.6 7.1 22.0 30.7 132.2 14.3 24.2 19.8 24.7 13.1 11.6 21.7 42.0 20.0 13.3 4.2 23.2 27.4 30.5 0.0 0.2 1.7 9.4 0.0 0.0 0.1 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.7 0.0 10.4 1.9 19.1 3.6 0.6 32.4 8.1 0.0 0.2 0.0 0.7 0.0 0.0 2.3 2.3 0.4 0.0 14.8 0.9 0.8 0.0 0.2 1.0 0.2 0.0 5.4 1.5 0.0 0.1 0.0 4.1 0.3 0.0 0.0 3.6 1.6 7.0 1.0 0.0 4.4 0.0 0.0 0.0 0.0 20.0 1.2 0.3 0.0 0.0 0.0 0.1 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.9 35.2 17.9 40.2 37.1 20.1 18.6 19.1 19.6 19.8 21.7 30.5 12.4 0.0 0.0 10.1 0.1 50.1 6.4 26.3 13.6 1.2 0.9 4.7 7.9 1.5 2.1 0.0 0.0 0.3 1.3 0.1 1.9 0.0 0.2 0.1 0.7 27.2 0.0 0.0 100.2 0.0 0.2 16.0 0.5 0.4 0.0 16.4 8.2 0.2 0.3 0.0 41.3 0.1 0.0 0.0 6.4 1.5 22.4 0.6 14.2 3.7 0.0 0.3 0.0 22.6 23.2 0.1 2.5 60.5 0.0 3.0 0.3 0.4 1.1 2.1 32.9 7.9 119.4 0.0 5.7 2.1 37.2 0.3 1.0 6.0 0.3 1.3 CCDC70 "DKFZP434K1172, FLJ25853" ENSG00000123171 "Coiled-coil domain containing 70" Q6NSX1 13 51861969-51866232 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 233 "testis: 135.2" "Group enriched" "Detected in some" 122 "Early spermatids: 982.5;Late spermatids: 3017.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA079644 Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA079644: " "unprognostic (5.73e-3)" "unprognostic (1.88e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 135.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 982.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3017.7 13.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCER2 ENSG00000262484 "Coiled-coil glutamate rich protein 2" I3L3R5 19 38908980-38912158 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 8 "Melanocytes: 617.2" "Group enriched" "Detected in many" 5 "glioma: 5.1;testis cancer: 1.9;urothelial cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.4;THP-1: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069716 Uncertain "Secreted - unknown location" NA NA 8800 "Cluster 27: Brain & Skin - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA069716: AB_2686183" "unprognostic (6.58e-2)" "unprognostic (2.24e-2)" "unprognostic (5.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (2.76e-3)" "unprognostic (3.88e-2)" "unprognostic (2.16e-1)" "unprognostic (5.97e-2)" "unprognostic (1.45e-1)" "unprognostic (4.08e-3)" "unprognostic (3.82e-2)" "unprognostic (1.01e-9)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.32e-4)" 0.5 0.6 2.2 0.2 2.4 0.7 0.8 2.3 3.4 1.2 1.8 0.9 0.3 0.7 0.3 1.2 1.1 0.1 0.9 2.3 2.2 1.8 2.9 0.5 0.3 2.9 2.2 0.7 0.5 0.2 2.5 0.1 2.4 1.4 0.1 1.0 0.9 0.2 2.3 4.2 0.9 0.1 2.1 1.1 0.6 4.9 2.2 0.4 1.2 0.0 0.1 0.9 0.8 2.4 0.1 1.4 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.0 0.6 0.5 0.1 0.2 0.1 0.0 0.0 0.0 0.9 0.2 0.9 0.0 0.9 0.2 0.4 0.3 0.0 0.2 0.7 0.1 0.2 0.1 0.6 0.4 0.2 0.1 0.1 0.0 0.1 1.0 1.4 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 2.3 3.4 2.3 2.2 2.9 2.2 2.4 2.1 2.2 2.4 0.1 3.2 0.0 3.9 0.1 76.9 0.1 0.1 0.0 2.5 0.4 0.5 0.4 1.5 0.1 1.8 4.2 0.4 0.4 0.3 0.0 0.0 1.4 0.3 0.2 0.6 1.2 0.4 2.3 0.0 0.1 0.8 0.0 0.5 0.0 0.3 0.0 0.6 0.2 0.0 3.3 0.2 0.0 0.3 7.2 4.9 0.3 0.2 617.2 0.0 0.0 1.3 0.0 3.5 2.2 0.1 0.2 0.0 0.0 0.1 0.2 0.2 0.4 3.8 0.0 0.4 0.7 1.1 2.1 0.0 3.0 0.3 0.4 0.2 0.6 0.1 CCK ENSG00000187094 Cholecystokinin P06307 3 42257825-42266185 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 317.9;choroid plexus: 89.5;intestine: 115.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.1;Excitatory neurons: 154.8;Fibroblasts: 42.5;Inhibitory neurons: 157.7;Melanocytes: 40.9;Oligodendrocytes: 40.9;Prostatic glandular cells: 63.8" "Group enriched" "Detected in many" 5 "glioma: 4.0;pancreatic cancer: 1.8;prostate cancer: 3.5;stomach cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "OE19: 236.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 74.4" "HPA045039, HPA069515" Enhanced Supported "Secreted to blood" NA NA 43700000 "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA045039: , HPA069515: AB_2732135" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (1.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (2.39e-3)" "unprognostic (1.97e-2)" "unprognostic (3.91e-1)" "unprognostic (8.77e-2)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (1.37e-1)" "unprognostic (5.10e-2)" 0.2 0.9 134.4 0.5 202.6 0.0 0.2 85.8 317.9 0.0 89.5 4.4 115.7 0.0 0.0 0.3 0.5 0.0 0.1 160.1 96.9 1.2 0.4 3.4 0.0 99.9 103.4 0.1 0.4 0.0 18.4 1.1 94.5 19.5 0.1 4.4 0.2 0.2 0.2 0.4 17.0 0.2 93.9 0.0 2.1 2.3 123.9 0.2 0.1 0.0 0.0 0.1 0.1 143.7 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 9.7 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 236.5 0.1 0.0 0.0 1.1 25.0 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 134.4 202.6 85.8 317.9 160.1 96.9 99.9 103.4 94.5 93.9 123.9 143.7 0.4 0.0 0.0 40.1 0.2 5.7 1.3 0.3 0.6 6.8 1.3 1.9 0.3 0.0 0.2 5.5 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.1 2.5 0.0 0.0 154.8 0.4 0.1 42.5 5.1 0.4 0.0 0.0 1.4 0.0 0.1 0.0 157.7 11.4 2.0 0.3 3.0 0.3 0.0 0.6 40.9 34.7 0.0 36.7 0.0 34.7 40.9 0.7 0.0 0.0 0.0 63.8 0.6 0.1 0.0 3.5 0.0 0.8 6.4 0.1 1.7 0.0 1.3 10.5 0.0 0.0 0.5 8.7 CCL1 "I-309, P500, SCYA1, SISe, TCA3" ENSG00000108702 "C-C motif chemokine ligand 1" P22362 17 34360328-34363233 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 2.2;lymphoid tissue: 1.2" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;granulocytes: 8.9;Late spermatids: 1.6;T-cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 38 "HMC-1: 702.6" HPA049861 Uncertain "Secreted to blood" NA NA 84400 "Cluster 25: Monocytes - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049861: AB_2680919" "unprognostic (6.52e-2)" "unprognostic (4.81e-3)" "unprognostic (5.84e-2)" "unprognostic (5.01e-1)" "unprognostic (6.04e-1)" "unprognostic (2.71e-1)" "unprognostic (1.37e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 702.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.4 0.8 0.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 CCL11 "eotaxin, MGC22554, SCYA11" ENSG00000172156 "C-C motif chemokine ligand 11" P51671 17 34285742-34288334 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.7;lymphoid tissue: 31.4;stomach 1: 35.1;urinary bladder: 41.0" "Cell type enriched" "Detected in some" 15 "Fibroblasts: 38.9" "Cancer enhanced" "Detected in many" "stomach cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "BJ hTERT+: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 88500 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.61e-2)" "unprognostic (1.45e-1)" "prognostic favorable (8.70e-4)" "unprognostic (8.18e-2)" "prognostic favorable (1.99e-4)" "unprognostic (9.91e-2)" "unprognostic (8.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (1.45e-1)" "unprognostic (9.64e-8)" "unprognostic (2.66e-2)" "unprognostic (1.05e-3)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" 3.8 0.8 0.0 31.4 0.0 0.0 0.2 0.0 0.0 3.6 0.0 41.7 33.2 1.7 0.0 12.4 0.7 4.8 16.7 0.0 0.0 5.8 0.6 9.1 0.0 0.0 0.0 0.3 2.8 1.7 1.0 0.0 0.0 2.6 14.7 0.0 0.1 0.9 0.0 0.0 35.8 20.5 0.0 2.8 35.1 0.0 0.0 0.3 0.0 0.0 0.7 41.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 9.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 1.9 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.1 CCL13 "CKb10, MCP-4, MGC17134, NCC-1, SCYA13, SCYL1" ENSG00000181374 "C-C motif chemokine ligand 13" Q99616 17 34356480-34358610 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.4;urinary bladder: 30.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 48.7;Langerhans cells: 81.2;Melanocytes: 17.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;BJ hTERT+: 1.7;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;HMC-1: 1.3;HSkMC: 1.7" "Secreted to blood" NA NA 336000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "unprognostic (2.22e-2)" "unprognostic (3.56e-2)" "unprognostic (8.41e-3)" "unprognostic (1.49e-3)" "unprognostic (4.43e-2)" "unprognostic (1.58e-1)" "unprognostic (7.58e-2)" "unprognostic (8.49e-2)" "unprognostic (1.18e-1)" "unprognostic (2.83e-2)" "unprognostic (1.35e-2)" "unprognostic (5.98e-2)" "unprognostic (8.63e-8)" "unprognostic (2.26e-1)" "unprognostic (2.57e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-2)" 24.0 4.5 0.0 7.0 0.0 0.3 18.4 0.0 0.5 3.2 0.0 30.4 21.3 0.6 0.3 11.9 4.4 2.7 11.8 0.0 0.0 1.7 0.2 22.5 3.2 0.0 0.0 0.3 0.7 1.6 0.1 9.7 0.0 1.6 25.1 0.0 2.6 0.8 0.6 4.5 27.0 9.0 0.0 0.1 2.9 2.4 0.0 8.7 1.8 5.8 1.8 30.4 3.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 1.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.0 0.0 0.0 8.8 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 81.2 0.3 0.0 6.6 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 0.0 0.1 4.7 0.3 1.0 0.0 0.0 0.1 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 83.0;liver: 31.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 262.6;Intestinal goblet cells: 208.3;Paneth cells: 380.6;Proximal enterocytes: 461.4;Undifferentiated cells: 138.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 35.4;OE19: 28.7" HPA058608 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 3270000 11000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" Vesicles "HPA058608: AB_2683776" "unprognostic (1.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "prognostic favorable (3.02e-4)" 0.2 0.4 0.1 7.8 0.1 0.1 0.4 0.1 0.3 0.3 0.0 59.7 37.6 0.1 0.0 0.2 9.6 9.2 0.0 0.1 0.1 10.0 31.6 2.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 83.0 0.0 0.1 0.1 0.0 0.1 62.0 1.4 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.3 4.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 28.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.1 7.2 5.0 0.0 0.0 0.0 0.0 262.6 0.0 0.0 0.0 12.2 0.1 0.7 71.8 0.0 0.0 0.7 0.0 0.0 0.0 0.1 8.9 0.0 2.5 40.2 0.1 0.0 0.0 208.3 2.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 380.6 0.0 0.0 0.0 461.4 61.3 76.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 138.2 0.2 CCL16 "CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4" ENSG00000275152 "C-C motif chemokine ligand 16" O15467 17 35976493-35981497 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "liver: 120.3" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 262.0" "Cancer enriched" "Detected in single" 154 "liver cancer: 49.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 10.1" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 2780000 23000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (3.85e-1)" "unprognostic (4.71e-1)" "unprognostic (1.49e-1)" "unprognostic (3.75e-2)" "unprognostic (2.72e-1)" "unprognostic (4.58e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (1.91e-2)" "unprognostic (3.57e-1)" "unprognostic (1.40e-3)" "unprognostic (1.66e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (4.08e-2)" 0.7 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.2 0.1 0.5 0.0 0.2 0.5 0.2 0.2 0.0 0.0 0.3 120.3 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.0 2.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 262.0 0.0 0.0 0.0 0.2 0.0 4.1 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 CCL17 "ABCD-2, SCYA17, TARC" ENSG00000102970 "C-C motif chemokine ligand 17" Q92583 16 57404767-57416063 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 21.1" "Cell type enriched" "Detected in some" 55 "monocytes: 12161.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 640 "HDLM-2: 2395.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "basal ganglia: 4.3" CAB002583 Uncertain "Secreted to blood" NA NA 248000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB002583: AB_564022" "unprognostic (4.62e-3)" "prognostic favorable (1.91e-5)" "unprognostic (5.83e-2)" "unprognostic (3.52e-4)" "unprognostic (4.51e-2)" "unprognostic (1.78e-3)" "unprognostic (4.44e-1)" "unprognostic (3.41e-2)" "unprognostic (6.36e-2)" "unprognostic (4.28e-2)" "unprognostic (4.11e-1)" "unprognostic (2.91e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-1)" "unprognostic (7.72e-3)" "unprognostic (4.14e-3)" "prognostic favorable (5.80e-4)" 1.2 0.1 0.1 8.3 0.1 0.0 1.9 0.1 0.4 1.4 0.0 1.5 0.1 0.0 0.0 3.1 0.6 2.9 1.3 0.2 0.0 0.6 0.3 4.5 8.4 0.1 0.0 0.2 0.5 0.1 0.0 0.1 0.1 0.3 2.7 0.0 2.5 0.2 0.1 2.4 3.7 2.6 0.0 0.8 0.7 0.5 0.1 21.1 0.8 0.2 5.7 3.4 0.9 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 3.3 0.0 0.0 0.0 2395.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.0 3.7 0.2 0.0 0.0 2.9 1.5 0.1 0.1 2.0 0.0 0.0 0.1 0.0 1.0 0.0 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.0 5.1 0.0 0.4 10.8 0.1 3.4 0.0 0.0 1.1 1.5 0.0 0.0 3.8 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.3 0.1 0.0 0.6 0.0 0.0 0.2 37.4 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.0 1.0 217.9 0.3 0.0 48.7 0.0 0.0 12161.5 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.0 0.4 2.1 0.0 0.0 0.0 12.0 0.0 0.5 0.0 2.7 0.0 0.4 0.0 0.0 0.7 CCL18 "AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18" ENSG00000275385 "C-C motif chemokine ligand 18" P55774 17 36064272-36072032 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lung: 48.7" "Group enriched" "Detected in some" 5 "Hofbauer cells: 189.1;Langerhans cells: 104.3;Macrophages: 153.1" "Cancer enhanced" "Detected in all" "lung cancer: 76.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 55500000 6400000 "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (8.91e-2)" "unprognostic (2.96e-2)" "unprognostic (5.71e-2)" "unprognostic (9.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" "unprognostic (2.50e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.68e-1)" "unprognostic (3.63e-1)" "unprognostic (4.87e-2)" 9.7 0.3 0.0 2.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 2.0 3.9 0.1 0.0 0.9 0.4 0.0 1.6 0.0 0.0 0.2 0.3 48.7 7.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 2.5 0.0 0.0 0.9 9.2 1.5 0.0 4.0 0.2 0.5 0.1 6.1 1.1 0.0 5.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 25.4 0.0 1.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 0.0 0.0 0.5 4.2 0.0 0.0 0.0 24.5 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.1 0.0 0.4 0.7 189.1 0.0 0.0 0.0 0.0 4.2 104.3 5.3 0.0 153.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.4 0.9 0.0 0.1 0.1 3.4 1.6 2.9 0.0 0.0 0.0 CCL19 "CKb11, ELC, exodus-3, MIP-3b, SCYA19" ENSG00000172724 "C-C motif chemokine ligand 19" Q99731 9 34689570-34691276 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 632.5" "Group enriched" "Detected in some" 12 "Basal keratinocytes: 74.7;Basal respiratory cells: 56.9;Fibroblasts: 59.6;Langerhans cells: 111.9;Melanocytes: 92.5;monocytes: 107.1;Smooth muscle cells: 150.9;Suprabasal keratinocytes: 54.0" "Cancer enhanced" "Detected in all" "testis cancer: 118.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HDLM-2: 3.2;TIME: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067758 Enhanced "Secreted to blood" NA NA 195000 63000 "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA067758: AB_2685897" "prognostic favorable (2.88e-5)" "prognostic favorable (9.91e-6)" "unprognostic (8.25e-3)" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (1.67e-2)" "unprognostic (1.30e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (8.36e-3)" "unprognostic (8.31e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (8.63e-7)" "unprognostic (7.98e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-1)" "unprognostic (1.87e-1)" 133.1 3.4 3.0 609.4 3.6 0.0 43.6 2.6 8.2 27.7 5.5 34.3 7.9 5.4 3.8 55.6 14.1 69.3 40.8 2.5 2.8 47.7 49.1 48.7 632.5 4.5 3.8 2.4 4.8 0.3 7.9 0.0 4.2 34.3 70.2 0.1 49.5 2.0 0.4 42.8 146.4 32.5 2.9 59.6 68.8 4.0 3.4 526.3 51.6 2.2 603.0 108.4 9.1 2.9 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.6 2.6 8.2 2.5 2.8 4.5 3.8 4.2 2.9 3.4 2.9 3.3 0.0 0.0 0.0 0.8 74.7 0.0 56.9 0.0 0.0 0.4 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 7.3 0.0 0.0 0.0 0.2 0.0 59.6 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 1.3 111.9 0.2 0.0 3.7 92.5 1.0 107.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 150.9 0.7 0.6 0.9 54.0 0.0 6.6 0.0 0.0 0.5 CCL2 "GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF" ENSG00000108691 "C-C motif chemokine ligand 2" P13500 17 34255218-34257203 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 756.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1152.5;Ductal cells: 3382.2;Exocrine glandular cells: 919.2;Prostatic glandular cells: 889.0;Skeletal myocytes: 994.7;Smooth muscle cells: 1507.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 7.5;eosinophil: 3.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.0;monocytes: 7.5" "Group enriched" "Detected in many" 4 "BJ hTERT+: 1902.2;HMC-1: 2427.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 9.9;spinal cord: 39.4" "CAB013676, HPA019163" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 323000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" Vesicles "CAB013676: , HPA019163: AB_1846179" "unprognostic (6.43e-2)" "unprognostic (4.14e-2)" "unprognostic (4.78e-2)" "unprognostic (5.57e-2)" "unprognostic (2.37e-3)" "unprognostic (8.64e-2)" "unprognostic (2.78e-2)" "unprognostic (7.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" "unprognostic (9.33e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (1.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.81e-1)" "unprognostic (4.92e-2)" 390.9 129.8 15.6 167.2 15.1 96.5 76.8 14.7 26.8 20.4 24.4 169.5 41.2 30.2 15.0 47.1 85.6 256.5 305.8 16.0 21.1 229.5 161.1 405.1 78.4 32.7 16.5 19.3 141.6 34.6 70.5 39.1 21.9 153.1 103.5 11.5 47.0 45.4 19.6 40.3 80.3 150.7 21.4 73.2 121.2 12.1 43.3 142.7 84.4 47.0 16.6 756.1 36.3 25.3 0.1 15.3 40.4 0.0 110.7 94.5 0.3 116.6 1902.2 243.3 516.8 7.1 0.2 0.3 90.4 27.6 3.8 64.0 4.3 0.1 122.9 0.6 0.9 0.2 13.5 0.0 3.5 0.4 2427.9 105.9 0.0 50.6 2.9 162.6 112.4 0.0 6.5 20.2 0.0 0.0 0.7 19.6 5.8 0.0 0.4 0.6 3.3 20.9 354.7 0.0 0.1 8.1 0.3 6.0 3.3 108.4 4.6 2.5 6.4 129.0 5.7 3.6 0.7 1.2 0.5 0.1 75.7 37.6 84.3 0.0 7.5 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.6 15.6 15.1 14.7 26.8 16.0 21.1 32.7 16.5 21.9 21.4 43.3 25.3 218.3 182.7 126.5 2.0 3.6 568.6 866.2 595.3 1152.5 0.1 23.5 50.9 29.5 92.9 120.7 138.0 0.0 2.7 2.2 0.0 0.0 3382.2 0.0 8.4 37.8 577.2 0.0 0.0 0.7 919.2 3.6 840.5 5.6 11.4 353.0 0.1 50.3 0.4 439.1 0.0 0.1 0.0 6.1 8.9 408.5 0.4 12.2 593.1 213.5 8.4 37.8 13.8 0.0 0.0 0.1 781.2 0.0 1.5 2.9 889.0 0.0 67.7 27.7 0.7 131.5 994.7 1507.0 0.4 0.3 13.0 222.8 4.5 44.3 1.7 0.1 40.6 CCL20 "CKb4, exodus-1, LARC, MIP-3a, SCYA20, ST38" ENSG00000115009 "C-C motif chemokine ligand 20" P78556 2 227805739-227817564 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Antibiotic, Antimicrobial, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 162.6;lymphoid tissue: 165.5;urinary bladder: 192.8" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 25281.7;Club cells: 7424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.7" "Lineage enriched" "Detected in single" 9 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "GAMG: 63.1;Hep G2: 35.7;NB-4: 25.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 28000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.40e-1)" "unprognostic (1.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (7.06e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (9.29e-4)" "unprognostic (1.53e-3)" "unprognostic (1.37e-1)" "unprognostic (5.21e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.19e-8)" "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (1.63e-1)" "unprognostic (1.82e-1)" 10.1 0.3 1.9 31.8 2.2 7.3 0.7 3.6 2.7 23.9 0.2 19.7 16.4 13.7 0.8 12.2 2.7 162.6 2.0 1.9 1.5 9.1 20.1 35.4 6.2 1.9 1.4 0.9 1.8 0.2 0.2 1.3 2.1 2.8 27.0 1.8 5.0 0.5 0.6 8.2 26.6 4.7 1.5 0.4 11.2 2.1 2.6 2.6 0.6 0.2 165.5 192.8 4.6 3.5 0.5 1.4 0.7 0.9 3.2 6.0 0.9 0.4 2.1 0.2 0.8 3.9 0.6 1.3 4.4 0.0 63.1 0.7 0.2 8.7 1.4 0.9 1.5 0.2 3.3 35.7 2.4 4.7 0.4 10.1 1.8 2.0 2.4 1.0 0.0 1.2 0.3 5.1 0.5 0.4 0.3 25.7 1.8 5.3 0.8 0.7 8.6 1.0 0.3 15.4 0.6 0.5 0.3 1.5 0.9 0.8 1.4 5.7 2.3 3.3 4.1 7.2 0.7 1.0 3.2 2.1 5.0 3.5 6.6 0.0 0.1 0.0 0.0 0.0 2.7 0.1 1.1 0.6 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 1.9 2.2 3.6 2.7 1.9 1.5 1.9 1.4 2.1 1.5 2.6 3.5 2.8 48.1 108.5 0.0 5.6 118.8 554.4 25281.7 21.6 0.6 1.9 1.9 0.9 65.8 7424.9 18.4 0.0 0.5 2.4 135.0 0.0 310.9 16.0 51.9 44.4 5.1 57.9 0.0 0.0 2.9 0.5 9.2 50.4 517.8 5.7 0.0 0.0 1.7 29.1 1.7 0.0 161.0 2203.3 4.0 149.2 1.2 0.0 333.0 1.8 0.0 9.4 0.0 0.0 0.0 0.0 24.1 459.7 0.0 4.5 259.5 331.0 9.3 1477.8 0.2 0.0 0.7 115.1 1.2 1.2 224.9 64.8 0.8 68.2 0.0 121.9 1062.1 CCL21 "6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4" ENSG00000137077 "C-C motif chemokine ligand 21" O00585 9 34709005-34710136 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 2726.3" "Cell type enriched" "Detected in many" 8 "Endothelial cells: 1213.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.1;K-562: 1.2" "Low region specificity" "Detected in some" HPA051210 Enhanced "Secreted to blood" NA NA 198000 920000 "Cluster 16: Immune cells - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051210: AB_2681390" "unprognostic (3.06e-3)" "unprognostic (7.19e-3)" "unprognostic (9.89e-2)" "unprognostic (5.50e-2)" "unprognostic (4.51e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" "unprognostic (8.07e-2)" "unprognostic (4.15e-2)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (8.99e-3)" "unprognostic (3.50e-3)" "unprognostic (1.58e-1)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 173.7 46.9 0.0 269.5 0.1 0.0 180.7 0.1 0.3 154.7 0.6 111.7 46.3 75.6 34.1 128.2 253.3 80.8 41.7 0.1 0.1 75.1 66.0 196.4 2726.3 0.4 0.0 33.9 15.3 0.8 2.5 1.7 0.2 38.2 135.7 0.0 21.5 19.0 6.8 46.4 498.8 69.0 0.0 336.8 60.9 10.3 0.1 28.8 519.4 30.6 998.8 74.1 50.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.7 0.2 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.0 0.1 0.2 58.4 22.4 53.3 0.0 1.9 145.3 2.4 3.8 1.8 0.0 13.5 4.3 10.1 0.0 13.0 1.8 0.0 0.2 1.4 0.2 0.0 10.0 5.7 0.1 0.3 1213.6 0.0 2.7 0.0 3.6 0.2 22.9 0.0 0.2 11.4 0.0 107.1 0.5 0.6 0.0 0.0 2.1 0.0 1.8 148.8 11.0 0.6 6.5 144.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.4 29.6 1.5 0.0 0.0 10.2 0.0 0.0 3.4 120.0 0.2 0.3 11.5 137.7 0.3 9.2 0.0 0.0 0.4 CCL22 "A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1" ENSG00000102962 "C-C motif chemokine ligand 22" O00626 16 57358783-57366189 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.2;lymphoid tissue: 14.8;skin 1: 6.6;urinary bladder: 4.5" "Cell type enriched" "Detected in some" 27 "monocytes: 5366.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 18 "HDLM-2: 49.6" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 617000 "Cluster 17: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (2.67e-2)" "unprognostic (7.68e-3)" "prognostic favorable (2.98e-4)" "prognostic favorable (2.23e-6)" "unprognostic (8.87e-2)" "prognostic favorable (9.17e-5)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (1.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.85e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (7.71e-2)" "unprognostic (3.43e-2)" "unprognostic (3.12e-2)" "unprognostic (3.88e-2)" 0.7 0.3 0.3 13.5 0.2 0.6 1.4 0.8 0.3 0.7 0.4 1.6 1.2 0.3 0.1 1.8 0.3 1.8 0.1 0.2 0.1 0.2 0.7 1.8 5.9 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.3 0.4 5.2 0.2 0.7 0.4 0.4 6.6 3.1 0.9 0.1 1.9 1.5 0.4 0.2 14.8 0.3 0.3 14.5 4.5 0.6 0.8 0.5 0.2 0.2 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.7 0.3 0.1 0.1 0.0 1.2 0.1 0.1 0.1 49.6 0.1 0.2 0.3 0.5 0.0 0.2 1.4 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.3 0.3 0.0 0.1 0.2 0.4 0.4 0.2 0.0 0.1 0.2 1.8 0.0 2.7 0.3 0.2 0.2 2.1 0.0 0.2 0.2 2.4 0.4 0.2 0.2 0.1 0.2 0.2 0.1 0.4 0.0 0.2 0.1 1.6 0.2 0.2 0.2 0.1 0.1 1.0 0.1 0.1 0.9 0.4 0.1 0.2 1.2 0.4 0.1 0.3 0.1 0.1 0.3 0.2 0.8 0.3 0.2 0.1 0.3 0.1 0.3 0.1 0.2 0.8 0.1 3.2 1.1 0.0 4.2 6.6 0.3 0.6 0.0 0.0 1.3 0.6 0.4 0.0 1.2 0.0 0.0 0.0 0.1 0.1 1.9 5.9 0.0 0.3 0.1 0.8 0.0 0.0 0.0 21.1 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 194.6 0.0 0.0 10.4 3.6 0.0 5366.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 3.9 0.0 0.0 0.0 8.0 0.1 1.2 0.0 0.1 0.4 CCL23 "Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23" ENSG00000274736 "C-C motif chemokine ligand 23" P55773 17 36013056-36017972 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Hepatic stellate cells: 243.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 163 "eosinophil: 183.7" "Lineage enriched" "Detected in many" 163 "granulocytes: 183.7" "Group enriched" "Detected in some" 4 "HEL: 17.6;THP-1: 37.4" HPA042015 Uncertain "Secreted to blood" NA NA 937000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042015: AB_10794039" "unprognostic (1.65e-3)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (9.50e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (1.20e-4)" "unprognostic (2.17e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-2)" "unprognostic (7.05e-2)" "unprognostic (6.93e-2)" "unprognostic (1.35e-3)" "unprognostic (2.18e-1)" "unprognostic (2.76e-1)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" 7.9 6.7 0.0 7.0 0.0 3.7 7.3 0.0 0.2 18.5 0.1 4.3 0.2 14.8 1.6 4.7 11.9 3.3 0.7 0.0 0.0 12.0 7.5 21.4 1.6 0.0 0.0 2.9 1.0 0.0 0.3 0.3 0.0 8.6 8.7 0.0 3.5 0.3 0.5 3.6 9.3 10.8 0.0 14.1 3.3 0.6 0.1 0.8 3.1 0.1 1.3 5.5 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 2.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 1.0 0.7 183.7 0.1 0.7 0.0 1.0 0.0 0.4 0.7 0.0 0.0 0.4 0.7 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.5 3.2 2.3 0.0 0.9 1.7 0.4 0.0 0.0 0.0 0.1 0.3 0.2 1.5 0.6 0.0 0.0 0.0 0.7 1.6 0.0 0.0 1.6 0.0 0.2 44.6 0.0 5.7 0.0 0.0 0.0 0.7 0.0 0.0 10.1 0.0 243.8 2.6 7.0 0.0 0.0 0.5 0.0 14.7 2.7 0.1 0.0 3.7 1.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21.4 0.0 0.1 0.1 0.5 0.1 1.5 0.0 0.0 0.0 0.5 0.0 0.1 0.1 2.7 0.3 0.6 0.0 4.2 0.2 CCL24 "Ckb-6, eotaxin-2, MPIF-2, MPIF2, SCYA24" ENSG00000106178 "C-C motif chemokine ligand 24" O00175 7 75810825-75823356 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 71.4;lymphoid tissue: 71.8" "Cell type enhanced" "Detected in single" "Macrophages: 1.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 67.6;pancreatic cancer: 17.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.6;OE19: 2.3;U-2 OS: 4.8" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 4 "spinal cord: 9.9" "Secreted to blood" NA NA 276000 "Cluster 11: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (4.55e-2)" "unprognostic (1.13e-1)" "prognostic favorable (5.41e-4)" "unprognostic (1.26e-2)" "unprognostic (1.44e-2)" "unprognostic (5.56e-2)" "unprognostic (1.73e-1)" "unprognostic (1.93e-1)" "unprognostic (4.32e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (3.15e-1)" "unprognostic (2.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" 2.8 0.4 0.4 16.0 0.3 0.8 1.0 1.1 0.6 0.7 0.4 27.4 23.0 0.5 1.2 2.4 0.3 2.0 0.7 0.5 0.2 0.5 5.0 14.2 14.0 0.4 0.3 0.4 0.4 0.5 0.1 0.2 0.4 0.4 71.4 0.5 0.8 0.6 0.5 0.9 63.5 2.3 0.2 71.8 3.5 1.3 0.5 1.6 0.5 0.7 3.2 12.2 0.6 1.2 0.1 0.4 0.3 0.3 0.2 0.6 0.3 0.0 0.1 0.1 0.0 0.1 4.6 0.4 1.4 0.0 0.2 0.3 0.2 0.1 0.2 0.1 0.4 0.1 0.4 0.1 0.0 0.1 1.3 0.9 0.3 0.1 0.1 0.2 0.1 0.2 0.4 0.4 0.0 0.0 0.2 0.6 0.1 2.3 0.2 0.3 1.6 0.2 0.1 0.3 0.3 0.2 0.1 0.2 0.0 0.2 0.4 1.2 0.1 0.4 4.8 0.4 0.4 0.3 0.1 0.1 0.5 0.2 0.1 0.7 0.2 0.1 0.1 0.7 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.5 0.3 0.0 0.2 0.1 0.0 0.4 0.3 1.1 0.6 0.5 0.2 0.4 0.3 0.4 0.2 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 CCL25 "Ckb15, SCYA25, TECK" ENSG00000131142 "C-C motif chemokine ligand 25" O15444 19 8052318-8062660 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 1030 "intestine: 581.5;lymphoid tissue: 771.3" "Cell type enhanced" "Detected in some" "Intestinal goblet cells: 149.1;Proximal enterocytes: 774.7;Undifferentiated cells: 399.3" "Group enriched" "Detected in many" 4 "liver cancer: 25.4;stomach cancer: 33.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "NK-cell: 3.5" "Lineage enriched" "Detected in single" 5 "NK-cells: 3.5" "Cell line enhanced" "Detected in some" "BEWO: 2.0;HEL: 2.1;NB-4: 2.6;REH: 6.1;RPMI-8226: 1.8;SH-SY5Y: 1.9" HPA055883 Approved "Secreted to blood" NA NA 183000000 "Cluster 48: NK-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA055883: AB_2682955" "unprognostic (9.22e-3)" "unprognostic (3.13e-4)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "unprognostic (2.87e-1)" "unprognostic (9.30e-3)" "unprognostic (2.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (8.85e-3)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-4)" "unprognostic (6.43e-2)" "unprognostic (3.86e-1)" "unprognostic (6.57e-2)" "unprognostic (2.17e-1)" 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.2 0.5 0.0 0.1 1.3 512.4 0.3 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.2 0.0 1.4 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 581.5 0.0 0.1 0.5 0.5 0.6 0.3 771.3 0.2 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.6 0.1 0.0 0.3 6.1 0.0 1.8 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.5 0.2 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.2 1.6 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 149.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 57.6 0.0 1.5 0.0 774.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 399.3 0.0 CCL26 "eotaxin-3, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1" ENSG00000006606 "C-C motif chemokine ligand 26" Q9Y258 7 75769533-75789896 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 20.4;pituitary gland: 16.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 7.1;Intestinal goblet cells: 7.7;Leydig cells: 16.8;Sertoli cells: 13.1;Smooth muscle cells: 20.2" "Cancer enhanced" "Detected in many" "testis cancer: 14.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 11.2;hTEC/SVTERT24-B: 14.8;PC-3: 51.1;U-2 OS: 13.7" "Region enriched" "Detected in single" 16 "spinal cord: 1.7" "Secreted to blood" NA NA 117000 "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (3.52e-2)" "unprognostic (2.18e-2)" "unprognostic (6.17e-2)" "unprognostic (3.02e-1)" "unprognostic (8.71e-2)" "unprognostic (7.93e-2)" "unprognostic (2.47e-1)" "unprognostic (1.05e-11)" "unprognostic (2.46e-2)" "unprognostic (1.10e-1)" "unprognostic (3.73e-1)" "unprognostic (6.29e-3)" 2.7 3.1 1.5 0.6 1.7 0.0 1.9 1.6 3.7 3.1 10.1 0.8 0.3 1.2 1.9 1.8 2.7 1.4 3.9 1.5 1.5 1.7 0.4 1.9 3.4 1.7 1.5 20.4 0.4 3.2 16.4 0.4 1.6 1.0 7.2 2.5 0.7 0.3 0.4 1.9 1.0 1.4 1.7 0.4 0.9 1.2 1.9 0.3 0.6 0.1 0.2 3.6 4.3 1.5 0.2 11.2 0.0 0.0 1.3 1.7 0.0 0.6 5.2 4.3 7.3 0.3 3.2 0.0 7.2 3.5 0.3 2.1 0.0 0.0 5.8 0.0 0.5 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.6 14.8 0.1 2.3 0.0 0.0 5.2 0.0 2.2 0.7 0.0 0.0 8.4 0.5 51.1 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.6 0.1 0.0 2.2 0.0 0.0 0.3 8.2 13.7 4.2 2.7 0.0 0.0 0.0 2.5 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.6 3.7 1.5 1.5 1.7 1.5 1.6 1.7 1.9 1.5 0.5 0.0 0.0 0.0 0.0 1.1 3.5 1.8 0.0 0.5 0.1 0.1 0.4 0.0 0.7 0.0 4.2 0.0 0.0 2.3 0.0 0.0 0.5 0.1 1.1 0.6 0.0 0.0 0.1 0.0 0.0 7.1 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.0 0.1 7.7 0.0 3.2 1.4 0.9 16.8 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 4.9 0.0 0.6 0.1 0.0 0.2 2.2 13.1 0.9 20.2 0.1 0.4 0.6 1.8 0.0 0.2 2.5 1.6 2.6 CCL27 "ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine" ENSG00000213927 "C-C motif chemokine ligand 27" Q9Y4X3 9 34661880-34664048 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 485.0" "Group enriched" "Detected in some" 26 "Basal keratinocytes: 704.5;Suprabasal keratinocytes: 1004.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.9" "Not detected" "Not detected" HPA073848 Enhanced "Secreted to blood" NA NA 436000 1800000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 61: Skin - Cornification" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "HPA073848: AB_2732243" 0.3 0.0 1.8 0.1 1.8 1.6 27.6 3.5 4.8 0.6 1.5 0.1 0.3 0.7 3.1 0.7 0.2 0.7 0.6 1.8 1.8 0.0 0.3 0.1 0.3 2.0 1.8 0.9 0.1 0.1 0.1 0.3 1.9 0.2 0.2 0.9 0.3 0.1 1.4 485.0 0.1 0.2 1.9 0.1 0.1 1.3 1.8 4.6 1.2 0.3 0.2 0.1 0.6 2.2 0.0 0.0 0.3 1.9 0.8 0.3 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 1.1 0.7 0.0 0.0 1.1 0.4 0.3 0.0 0.0 1.4 0.8 0.2 0.0 0.3 0.0 0.5 0.2 1.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 1.3 0.7 0.0 0.0 0.9 0.8 0.7 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 1.8 3.5 4.8 1.8 1.8 2.0 1.8 1.9 1.9 1.8 2.2 0.1 0.0 0.0 0.3 0.0 704.5 0.3 0.3 0.0 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 7.8 0.0 0.3 1.7 0.0 0.0 0.2 0.2 0.8 2.3 0.0 0.1 0.0 0.1 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.0 28.4 9.6 0.3 0.0 32.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.2 0.0 0.2 1.6 4.5 1.5 0.0 1004.0 1.9 0.8 0.0 0.2 0.1 CCL28 "CCK1, MEC, SCYA28" ENSG00000151882 "C-C motif chemokine ligand 28" Q9NRJ3 5 43376645-43412391 "Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 302.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 192.4;Breast myoepithelial cells: 147.4;Distal enterocytes: 172.9;Ductal cells: 110.1;Paneth cells: 117.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 10.7;EFO-21: 12.8;SiHa: 29.9;SK-MEL-30: 16.7;T-47d: 40.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA077434 Supported "Secreted to blood" NA NA 700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 30: Mammary glandular cells - Lactation" "HPA077434: AB_2732346" "unprognostic (1.04e-2)" "unprognostic (2.66e-1)" "unprognostic (8.14e-3)" "unprognostic (1.94e-2)" "unprognostic (8.85e-4)" "unprognostic (4.93e-3)" "unprognostic (1.20e-3)" "unprognostic (3.56e-2)" "unprognostic (4.91e-3)" "unprognostic (4.14e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (2.52e-1)" "unprognostic (1.78e-1)" "unprognostic (6.53e-2)" 1.7 1.2 0.7 4.6 0.9 3.3 60.9 0.8 0.9 14.3 0.9 30.7 24.1 2.3 1.4 4.0 4.3 19.7 1.0 0.7 0.5 2.8 1.8 2.9 4.6 0.8 1.5 1.5 7.9 2.2 1.1 3.1 0.9 3.1 28.3 2.1 302.4 2.3 0.3 5.4 12.6 1.9 0.4 4.3 15.0 1.6 0.5 2.4 22.6 0.5 3.9 1.4 2.1 1.5 0.8 0.0 0.1 0.2 0.9 0.1 4.7 0.7 0.4 0.0 0.0 2.1 10.7 0.1 12.8 0.3 0.0 1.6 0.0 0.2 0.0 0.1 0.2 0.8 1.2 0.0 0.7 0.1 0.2 1.0 2.7 0.2 0.5 0.4 0.1 0.1 0.1 0.1 1.2 0.2 1.9 0.1 0.1 0.0 1.6 0.1 0.0 0.5 0.1 1.3 0.2 0.1 29.9 1.1 16.7 0.3 40.1 8.0 0.2 0.1 1.2 0.2 0.1 0.7 0.1 0.1 0.0 0.1 8.9 4.0 0.2 0.3 3.2 0.2 2.5 4.0 3.7 2.7 0.6 4.3 4.3 3.1 0.7 3.5 0.1 0.9 6.0 1.4 0.7 0.9 0.8 0.9 0.7 0.5 0.8 1.5 0.9 0.4 0.5 1.5 4.0 0.0 7.7 1.6 10.9 2.7 4.9 15.6 5.7 0.1 192.4 147.4 0.4 62.9 17.9 5.5 0.0 6.2 10.1 172.9 5.9 110.1 3.7 12.9 1.9 6.4 3.6 2.5 1.7 66.4 3.2 2.9 36.2 13.0 11.4 0.0 7.5 1.9 2.6 0.0 0.7 48.5 20.3 1.2 1.2 1.2 12.5 1.5 17.8 2.8 1.3 9.6 17.5 0.5 0.9 21.7 117.0 4.9 1.2 13.7 38.7 0.2 46.2 0.9 0.0 0.4 2.6 5.3 3.1 6.1 1.3 2.7 9.5 0.5 58.5 24.4 CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.7;lung: 35.8;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in many" "dendritic cells: 441.4;Hofbauer cells: 2084.4;Kupffer cells: 723.2;Langerhans cells: 710.0;Macrophages: 1534.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.6" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.6" "Cell line enhanced" "Detected in some" "Karpas-707: 443.8;U-266/70: 602.5;U-266/84: 2043.3" "Secreted to blood" NA NA 138000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (7.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-1)" "unprognostic (8.90e-2)" "unprognostic (7.92e-3)" "unprognostic (2.00e-1)" "unprognostic (7.20e-2)" "unprognostic (2.05e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-2)" 17.6 16.0 0.0 8.1 0.7 76.7 5.6 0.0 1.4 1.5 0.0 2.5 0.0 1.1 0.0 0.5 2.9 10.3 3.7 0.0 0.0 4.6 12.9 35.8 1.8 0.7 0.0 1.2 1.3 0.0 1.7 2.4 0.0 2.2 0.0 0.0 5.6 0.0 0.8 0.8 3.1 0.0 0.0 49.4 3.0 0.7 0.5 0.0 2.0 0.0 0.0 3.0 1.4 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.8 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 55.6 0.0 0.0 1.3 602.5 2043.3 0.0 0.0 0.0 0.0 0.0 2.1 10.8 23.6 1.3 0.0 5.1 0.0 6.1 0.4 10.4 0.1 6.8 10.5 3.5 1.3 0.0 0.0 11.6 0.0 0.7 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.5 1.4 33.0 0.0 28.6 0.0 45.3 27.9 2.0 0.2 1.2 1.8 23.1 50.0 2.2 4.3 4.4 0.0 0.0 19.0 441.4 0.7 0.0 0.6 1.5 1.6 2.5 115.9 0.0 61.9 0.0 0.2 22.6 14.5 2.0 2.8 23.5 0.1 27.1 9.1 2084.4 0.0 0.0 0.5 0.0 723.2 710.0 1.9 1.8 1534.2 94.3 2.8 23.5 2.1 106.1 0.0 0.0 0.4 0.0 0.0 344.8 1.2 0.0 0.9 2.2 3.7 6.6 2.3 9.2 0.5 0.6 0.6 28.8 54.3 248.0 0.1 0.2 1.3 CCL3L3 "CCL3L1, D17S1718, G0S19-2, LD78BETA, MGC12815, SCYA3L, SCYA3L1" ENSG00000276085 "C-C motif chemokine ligand 3 like 3" P16619 17 36194869-36196758 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.0;lung: 5.0;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 6 "Hofbauer cells: 335.4;Kupffer cells: 227.5;Macrophages: 321.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "eosinophil: 4.2;neutrophil: 1.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Group enriched" "Detected in some" 41 "U-266/70: 49.4;U-266/84: 107.3" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "unprognostic (5.37e-2)" "unprognostic (1.46e-1)" "unprognostic (9.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.36e-2)" "unprognostic (3.69e-1)" "unprognostic (5.75e-2)" "unprognostic (5.55e-2)" "unprognostic (2.40e-2)" "unprognostic (3.66e-1)" "unprognostic (9.08e-2)" "unprognostic (2.09e-1)" "unprognostic (3.21e-1)" "unprognostic (1.90e-2)" "unprognostic (8.58e-2)" 1.6 0.9 0.0 0.3 0.0 11.0 0.7 0.0 0.3 0.1 0.0 0.5 0.1 0.2 0.2 0.1 0.7 0.9 0.4 0.0 0.0 1.1 1.2 5.0 0.5 0.0 0.0 0.2 0.2 0.0 0.3 0.3 0.0 0.5 0.0 0.0 1.3 0.1 0.1 0.1 0.8 0.1 0.0 4.0 0.5 0.5 0.0 0.1 0.3 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.1 49.4 107.3 1.2 0.0 0.0 0.0 0.1 0.0 4.2 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.3 0.5 0.0 2.2 0.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.9 0.0 0.7 0.0 0.0 0.1 0.0 0.0 48.8 0.0 16.0 0.0 0.0 4.4 1.3 0.5 0.0 0.0 0.0 8.6 1.0 335.4 0.0 0.0 0.5 0.0 227.5 2.9 0.9 0.6 321.7 1.8 1.9 1.6 0.7 10.3 0.0 0.0 0.0 1.2 0.0 0.8 0.7 0.0 0.0 0.0 2.3 0.0 0.4 0.3 0.4 3.8 0.7 0.1 13.1 31.4 0.0 0.0 0.4 CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "dendritic cells: 3753.7;Hofbauer cells: 849.7;Macrophages: 1168.2;NK-cells: 1232.8;Plasma cells: 974.5;T-cells: 1948.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Group enriched" "Detected in some" 6 "U-266/70: 51.6;U-266/84: 13.3" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" 38.9 28.0 2.0 32.0 2.0 192.9 10.5 3.4 5.5 16.0 4.1 9.9 7.6 10.3 6.4 15.0 8.2 45.1 4.4 2.0 1.9 6.8 84.2 33.9 34.3 3.2 2.9 5.0 15.6 12.0 2.5 17.8 2.8 7.6 11.1 0.1 5.1 3.4 1.0 0.9 11.4 18.0 2.5 65.3 10.3 2.7 2.1 24.1 5.9 4.5 15.4 56.4 4.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 51.6 13.3 0.2 0.2 0.1 0.0 14.4 3.4 135.0 414.7 4.8 101.6 8.4 46.0 240.6 2.3 17.7 13.8 181.7 55.8 42.8 11.1 2.6 0.5 138.9 2.0 2.0 3.4 5.5 2.0 1.9 3.2 2.9 2.8 2.5 2.1 3.3 52.3 0.0 54.5 0.0 135.9 15.6 1.9 0.3 24.5 1.5 26.3 49.3 11.2 14.3 7.2 0.0 0.0 9.7 3753.7 1.2 0.0 0.4 20.8 3.7 4.7 77.6 1.2 60.9 0.0 0.4 11.3 18.9 118.3 5.5 60.8 0.2 21.4 10.5 849.7 1.7 0.0 1.5 0.0 429.4 428.0 32.6 0.9 1168.2 51.6 3.7 10.5 1.1 1232.8 0.0 0.0 0.2 0.1 0.4 974.5 0.8 0.4 2.8 5.8 5.2 0.0 3.9 20.9 0.4 0.4 11.0 14.5 25.9 1948.3 0.0 0.9 1.6 CCL4L2 ENSG00000276070 "C-C motif chemokine ligand 4 like 2" Q8NHW4 17 36210924-36212878 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.2;lymphoid tissue: 20.5" "Group enriched" "Detected in many" 6 "dendritic cells: 488.0;Hofbauer cells: 358.5;Kupffer cells: 163.4;Macrophages: 585.2;NK-cells: 249.3;T-cells: 303.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 7 "eosinophil: 122.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 122.0" "Group enriched" "Detected in some" 4 "Daudi: 4.1;HMC-1: 5.6;U-266/70: 8.8" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" "unprognostic (2.46e-2)" "unprognostic (1.44e-2)" "unprognostic (1.16e-1)" "unprognostic (6.07e-2)" "unprognostic (3.82e-1)" "unprognostic (3.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.14e-1)" "unprognostic (3.62e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-2)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" "unprognostic (8.51e-2)" "unprognostic (1.99e-3)" 5.5 3.8 0.3 4.4 0.3 32.2 1.5 0.5 1.1 0.9 0.4 1.7 1.5 1.1 0.5 0.7 2.6 6.8 1.3 0.4 0.3 3.1 7.6 12.6 3.2 0.3 0.3 1.9 0.9 2.0 1.1 2.2 0.3 1.9 1.8 0.0 2.0 0.7 0.2 0.4 3.8 1.5 0.3 20.5 1.8 0.2 0.3 1.6 1.4 1.7 0.8 4.8 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.8 1.5 0.7 0.0 0.0 0.0 0.6 0.3 122.0 15.2 0.3 3.6 0.0 0.6 8.9 0.1 0.1 0.1 8.4 18.2 1.2 0.2 0.0 0.0 5.5 0.3 0.3 0.5 1.1 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.4 18.1 0.0 7.7 0.7 13.9 0.4 0.4 0.0 5.7 0.4 13.8 22.9 8.6 4.3 0.0 0.0 0.0 4.2 488.0 0.2 0.0 0.1 0.2 0.4 1.0 38.1 0.0 14.3 1.1 0.0 6.1 3.9 3.1 0.8 5.1 8.2 7.1 1.3 358.5 1.7 0.4 0.1 0.0 163.4 59.1 1.2 0.0 585.2 1.8 6.5 3.3 1.3 249.3 0.0 0.1 0.1 0.1 0.0 50.6 0.4 0.0 0.2 0.0 2.3 13.1 1.1 6.6 0.1 0.1 1.4 0.4 9.6 303.6 0.1 0.0 1.8 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCL7 "FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7" ENSG00000108688 "C-C motif chemokine ligand 7" P80098 17 34270221-34272242 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 25.9" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 56.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.5;BJ hTERT+ SV40 Large T+: 2.3;BJ hTERT+ SV40 Large T+ RasG12V: 2.8;HSkMC: 3.3" "Not detected" "Not detected" "Secreted to blood" NA NA 29700 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (7.66e-2)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (4.65e-2)" "unprognostic (2.54e-2)" "unprognostic (9.54e-2)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (2.63e-2)" "unprognostic (2.27e-3)" "unprognostic (7.04e-2)" "unprognostic (1.99e-8)" "unprognostic (2.83e-1)" "unprognostic (8.74e-2)" "unprognostic (3.74e-1)" "unprognostic (1.79e-2)" 0.8 0.2 0.0 2.5 0.0 25.9 0.1 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.7 0.3 0.0 0.0 0.5 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 2.3 0.3 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 11.5 2.3 2.8 0.0 0.0 0.0 0.4 0.8 0.0 1.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.3 0.0 0.9 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 CCL8 "HC14, MCP-2, SCYA8" ENSG00000108700 "C-C motif chemokine ligand 8" P80075 17 34319435-34321402 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Smooth muscle cells: 104.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 6 "monocytes: 3.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;EFO-21: 2.1;HSkMC: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 32000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (7.51e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-2)" "unprognostic (8.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (9.97e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.05e-7)" "unprognostic (1.39e-1)" "unprognostic (1.88e-2)" "unprognostic (5.65e-2)" "unprognostic (3.41e-2)" 17.5 4.7 0.4 5.1 0.4 1.8 6.2 0.4 0.9 1.5 0.5 18.1 14.1 7.3 1.9 3.5 1.3 8.8 2.7 0.4 0.4 7.7 3.2 7.1 3.9 0.6 0.4 1.4 1.1 4.8 0.5 7.1 0.6 2.2 16.4 0.0 1.9 1.3 0.4 0.5 17.0 9.3 1.8 2.9 2.9 3.1 1.1 12.5 2.3 7.0 0.5 13.7 0.3 0.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.4 0.9 0.4 0.4 0.6 0.4 0.6 1.8 1.1 0.6 21.5 0.0 0.0 0.0 0.1 4.2 0.3 0.5 0.0 0.0 0.9 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 10.5 0.9 7.5 9.6 0.0 0.0 0.0 2.0 0.0 16.4 0.0 1.6 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 3.5 18.6 2.2 0.0 12.7 5.4 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.3 104.3 0.0 0.0 0.0 5.4 0.1 0.8 0.7 0.0 0.1 CCN1 "CYR61, GIG1, IGFBP10" ENSG00000142871 "Cellular communication network factor 1" O00622 1 85580761-85584589 "Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 256.5;Cardiomyocytes: 107.6;Cytotrophoblasts: 258.1;Extravillous trophoblasts: 529.9;Fibroblasts: 296.2;Syncytiotrophoblasts: 131.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebral cortex: 25.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 431.8;BJ hTERT+ SV40 Large T+: 422.0;EFO-21: 410.9;SiHa: 551.2;TIME: 541.3;U-251 MG: 642.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029853 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA029853: AB_10611822" "unprognostic (6.09e-2)" "unprognostic (3.25e-2)" "unprognostic (9.97e-2)" "unprognostic (8.90e-2)" "unprognostic (1.80e-2)" "unprognostic (3.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.56e-2)" "unprognostic (2.59e-1)" "unprognostic (9.95e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (3.74e-3)" 571.1 99.7 1.0 28.2 3.9 0.2 313.4 1.0 25.0 255.7 9.6 197.1 5.1 273.6 0.1 48.7 472.4 64.8 400.6 3.7 0.0 212.8 200.5 407.8 3.8 4.9 3.8 123.1 70.7 14.8 56.0 29.8 3.1 157.3 1.7 1.1 94.2 2.9 97.8 197.1 102.0 141.7 0.0 131.2 201.7 20.1 5.1 11.1 268.1 17.3 0.0 264.4 150.8 3.6 159.3 5.2 0.7 1.0 47.4 90.6 77.4 431.8 216.6 422.0 264.6 24.1 4.3 0.0 410.9 185.5 82.8 36.3 15.9 33.4 164.4 0.7 6.9 0.3 6.8 0.7 245.2 3.7 0.2 39.9 6.9 121.2 50.1 13.4 366.0 0.1 1.6 0.0 150.3 0.8 0.3 0.7 24.9 1.8 42.2 0.4 94.9 0.7 166.0 2.5 0.4 4.0 551.2 17.7 62.1 4.9 16.5 0.8 541.3 272.3 213.3 82.2 642.6 0.3 0.7 1.8 1.9 0.2 73.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.9 1.0 25.0 3.7 0.0 4.9 3.8 3.1 0.0 5.1 3.6 256.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.6 0.0 0.0 0.0 0.0 258.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 529.9 296.2 0.0 0.0 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 89.1 0.0 0.0 0.0 0.0 131.3 0.0 0.0 0.0 0.0 CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 101.2;Cardiomyocytes: 38.7;Extravillous trophoblasts: 47.1;Fibroblasts: 261.8;Smooth muscle cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Cell line enhanced" "Detected in many" "EFO-21: 1605.0;HUVEC TERT2: 1377.0;TIME: 2874.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" No No 1010000 5900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 265.9 107.5 18.9 168.0 18.8 2.0 206.4 16.3 34.0 531.0 31.5 148.8 43.7 418.5 34.4 271.9 243.8 441.4 371.8 25.8 14.2 235.7 82.9 226.3 73.6 18.8 32.1 77.0 194.0 43.0 44.8 198.2 20.2 364.6 136.1 2.4 138.2 154.3 51.8 155.1 151.2 576.3 14.2 569.1 182.6 24.7 20.8 49.5 464.7 61.9 14.9 324.0 102.5 18.2 4.6 7.5 126.8 3.7 279.9 158.5 1.8 373.1 178.2 226.8 119.4 0.2 12.2 0.6 1605.0 482.7 185.0 6.2 4.2 26.4 211.3 2.5 3.5 0.2 55.7 137.3 109.6 0.3 0.5 232.2 5.9 163.9 40.2 340.7 1377.0 0.0 0.4 0.3 650.8 2.5 0.5 1.2 61.8 41.3 21.7 32.6 6.0 0.7 81.9 0.4 0.5 0.8 38.3 62.2 18.3 308.5 6.1 3.1 2874.4 311.6 242.4 397.8 694.0 11.5 1.7 4.1 42.5 0.7 399.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.9 18.8 16.3 34.0 25.8 14.2 18.8 32.1 20.2 14.2 20.8 18.2 101.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 0.0 17.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 47.1 261.8 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in some" "Adipocytes: 25.2;Endothelial cells: 2.7;Fibroblasts: 9.8;Smooth muscle cells: 4.6" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.0;hTERT-RPE1: 38.1;U-2197: 128.2" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 23.7 1105.4 7.6 3.6 11.5 1.7 8.1 6.7 12.2 11.2 5.9 6.9 3.9 8.6 6.3 5.5 9.0 6.3 18.1 16.2 9.7 6.9 1.1 6.8 2.2 5.6 6.5 3.1 6.8 9.4 21.8 0.6 4.9 22.8 7.0 1.2 2.7 20.0 4.7 13.8 4.4 8.4 8.7 1.5 4.9 3.6 6.3 1.0 25.3 7.2 1.9 4.4 8.0 6.2 0.1 3.1 1.7 0.0 11.1 2.9 0.1 16.9 125.0 14.9 8.6 0.0 0.3 0.0 12.9 21.2 11.6 10.5 0.6 0.0 5.1 0.0 0.3 0.0 9.1 0.0 0.4 0.0 0.0 0.6 0.1 5.7 0.6 38.1 0.4 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.2 1.2 24.9 0.1 0.0 0.0 15.8 0.1 3.9 0.1 6.3 0.1 24.2 0.0 0.0 0.0 0.0 10.6 15.8 128.2 3.5 0.0 0.0 0.0 16.7 5.4 12.5 0.0 0.3 64.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.1 7.6 11.5 6.7 12.2 16.2 9.7 5.6 6.5 4.9 8.7 6.3 6.2 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCN4 "WISP-1, WISP1, WISP1-OT1, WISP1-UT1" ENSG00000104415 "Cellular communication network factor 4" O95388 8 133191039-133231690 "Cancer-related genes, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 110.5;hTEC/SVTERT24-B: 64.5;U-2197: 61.9" "Region enriched" "Detected in some" 6 "olfactory bulb: 9.8" "Low region specificity" "Detected in many" "HPA007121, CAB012205" Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB012205: , HPA007121: AB_1858844" "unprognostic (7.77e-2)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (3.20e-1)" "unprognostic (7.72e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.26e-2)" "unprognostic (2.07e-3)" "unprognostic (1.41e-3)" "unprognostic (3.01e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (7.52e-3)" "unprognostic (2.55e-3)" "unprognostic (6.03e-2)" "unprognostic (5.67e-3)" 4.4 10.3 1.3 7.6 2.6 0.0 0.9 0.5 1.4 10.9 0.9 3.9 1.2 14.0 0.9 0.9 5.9 7.8 3.7 1.3 0.4 15.8 2.0 8.3 3.0 0.7 0.6 6.0 0.8 9.2 2.3 2.8 0.7 3.3 0.8 0.0 1.1 1.4 0.4 1.4 2.3 13.6 0.6 2.2 2.8 1.2 0.9 0.2 1.1 0.2 3.9 6.0 3.6 0.8 0.0 0.5 0.0 0.0 7.6 4.2 0.1 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 110.5 0.0 64.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.0 0.0 0.0 14.8 0.8 61.9 0.0 0.0 0.0 0.0 12.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.6 0.5 1.4 1.3 0.4 0.7 0.6 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCN5 "CT58, CTGF-L, WISP-2, WISP2" ENSG00000064205 "Cellular communication network factor 5" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 394.6;cervix: 355.7" "Cell type enriched" "Detected in some" 6 "Fibroblasts: 165.2" "Cancer enhanced" "Detected in many" "melanoma: 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 42.6;ASC TERT1: 113.8;HeLa: 62.7;HSkMC: 46.5;U-2197: 375.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB019273 Approved "Secreted to extracellular matrix" NA NA 1200000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB019273: " "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.42e-2)" "unprognostic (2.81e-1)" "unprognostic (7.95e-3)" "unprognostic (1.76e-10)" "unprognostic (1.55e-3)" "unprognostic (7.21e-2)" "unprognostic (4.84e-2)" "unprognostic (1.28e-1)" 394.6 41.5 1.8 0.7 2.0 0.2 116.5 0.9 2.9 355.7 0.7 23.6 0.7 35.3 0.7 25.4 39.0 7.7 161.1 1.6 1.3 0.7 5.6 136.4 1.9 1.4 1.4 147.1 4.4 0.6 0.8 1.4 1.4 37.0 1.6 0.1 30.7 25.5 39.2 197.1 11.5 6.5 1.0 4.0 11.4 33.1 1.4 1.3 14.2 5.1 0.4 36.7 111.6 1.5 0.0 3.7 0.1 0.0 42.6 113.8 0.0 0.2 1.2 0.1 0.2 0.0 0.0 0.1 0.5 0.7 3.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 62.7 0.0 0.1 0.1 0.1 46.5 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 1.1 0.3 0.0 1.9 0.2 0.0 0.1 0.2 375.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.0 0.9 2.9 1.6 1.3 1.4 1.4 1.4 1.0 1.4 1.5 25.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 165.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCN6 "WISP-3, WISP3" ENSG00000112761 "Cellular communication network factor 6" O95389 6 112054075-112069686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "epididymis: 10.2" "Cell type enriched" "Detected in single" 7 "Cardiomyocytes: 2.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 49 "RT4: 12.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064196 Supported Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA064196: AB_2685209" "unprognostic (2.13e-2)" "unprognostic (7.90e-3)" "unprognostic (5.00e-2)" "unprognostic (2.22e-2)" "unprognostic (3.76e-1)" "unprognostic (6.52e-2)" "unprognostic (1.98e-3)" "unprognostic (4.07e-3)" "unprognostic (1.82e-1)" "unprognostic (3.90e-1)" "unprognostic (1.02e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "unprognostic (3.11e-1)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 10.2 0.0 2.3 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD160 "BY55, NK1, NK28" ENSG00000117281 "CD160 molecule" O95971 1 145719471-145739288 "CD markers, Predicted secreted proteins" "Adaptive immunity, Angiogenesis, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.5" "Cell type enriched" "Detected in some" 6 "NK-cells: 410.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 107.6;MAIT T-cell: 44.5;memory CD8 T-cell: 72.9;naive CD8 T-cell: 82.8;NK-cell: 85.9" "Group enriched" "Detected in all" 8 "NK-cells: 85.9;T-cells: 107.6" "Cell line enhanced" "Detected in some" "HeLa: 2.2" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.54e-4)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.33e-1)" "unprognostic (3.40e-2)" "unprognostic (1.35e-1)" "unprognostic (8.25e-3)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.24e-2)" "unprognostic (7.49e-3)" "unprognostic (3.48e-5)" "unprognostic (4.05e-2)" "unprognostic (2.03e-1)" "unprognostic (2.89e-2)" "unprognostic (2.92e-4)" 0.5 0.3 1.0 1.0 0.9 5.2 0.6 2.9 0.8 0.8 0.9 1.6 4.7 0.7 0.4 0.4 0.6 1.0 1.5 0.8 0.2 0.4 5.0 1.4 3.6 0.4 0.3 0.4 0.4 0.0 0.5 0.4 0.3 0.5 1.0 1.4 1.5 0.5 0.8 1.1 4.5 0.1 0.1 13.5 0.8 0.5 0.6 0.3 0.4 0.1 1.5 0.9 0.5 0.6 0.5 0.4 0.6 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.1 0.0 1.3 0.6 1.2 2.2 0.5 0.0 0.8 1.2 0.0 0.1 0.0 0.1 0.2 0.0 0.6 0.3 0.5 0.0 0.6 0.4 1.5 0.4 0.3 1.1 0.1 0.0 0.4 0.0 0.2 0.4 0.6 0.3 0.5 0.2 0.4 0.5 0.8 0.6 0.5 0.2 0.3 1.1 0.8 0.6 0.2 0.2 0.9 0.1 12.7 0.3 0.3 107.6 0.6 44.5 1.1 1.2 72.9 0.2 1.2 0.7 82.8 5.6 85.9 1.7 1.2 0.0 81.3 1.0 0.9 2.9 0.8 0.8 0.2 0.4 0.3 0.3 0.1 0.6 0.6 1.1 0.0 0.0 0.7 1.0 0.1 0.2 0.1 0.0 1.8 0.6 0.4 0.5 0.0 0.0 0.0 10.4 0.1 59.8 3.1 0.0 0.1 4.4 0.7 0.5 1.0 0.0 6.6 0.5 0.4 0.0 0.9 3.1 0.8 2.5 0.3 3.9 0.4 0.0 6.7 0.4 0.5 0.0 4.6 0.4 11.1 0.0 0.9 0.0 0.0 1.3 0.9 410.9 0.5 0.2 0.0 0.1 0.0 2.7 0.4 0.3 0.2 0.0 2.9 0.0 1.1 0.4 0.1 0.2 0.0 0.1 0.1 44.0 0.3 1.0 0.2 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD40 "Bp50, p50, TNFRSF5" ENSG00000101017 "CD40 molecule" P25942 20 46118278-46129863 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 127.5;Basal respiratory cells: 126.0;Langerhans cells: 191.4;monocytes: 242.0;Prostatic glandular cells: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 139.4;naive B-cell: 157.9" "Group enriched" "Detected in all" 6 "B-cells: 157.9;monocytes: 43.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 76.0;Daudi: 42.1;EFO-21: 131.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002495, HPA031567, HPA031568, CAB072868" Enhanced "Secreted to blood" NA NA 705000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "CAB002495: AB_563562, CAB072868: AB_2665719, HPA031567: AB_2673936, HPA031568: AB_2673937" "unprognostic (6.41e-2)" "unprognostic (1.55e-2)" "unprognostic (7.08e-3)" "unprognostic (6.21e-2)" "unprognostic (4.23e-3)" "unprognostic (1.25e-1)" "unprognostic (7.64e-3)" "unprognostic (1.34e-1)" "unprognostic (4.15e-2)" "unprognostic (7.16e-2)" "unprognostic (2.48e-2)" "unprognostic (7.04e-2)" "prognostic unfavorable (4.48e-4)" "unprognostic (1.22e-1)" "unprognostic (4.95e-2)" "unprognostic (1.60e-2)" "unprognostic (2.28e-2)" 25.9 8.4 6.7 34.9 7.0 2.7 20.5 7.6 7.7 19.4 9.4 11.8 12.6 14.4 7.6 12.4 19.7 14.3 16.3 6.6 7.2 26.1 18.3 34.4 57.8 8.0 7.1 24.5 21.9 46.5 9.9 12.4 7.6 23.6 9.6 1.1 24.5 15.4 8.6 17.0 21.8 14.0 7.8 35.1 15.6 3.8 7.3 17.3 20.4 7.1 57.7 32.9 21.0 8.0 26.6 4.1 0.0 12.8 4.7 2.7 5.0 4.9 1.4 3.8 3.6 0.0 76.0 42.1 131.8 0.8 18.7 3.1 2.3 16.2 3.9 29.0 0.0 10.0 0.0 7.5 36.6 0.0 13.0 16.2 6.2 15.3 0.0 0.0 28.3 0.0 3.5 0.0 0.8 0.0 0.0 0.2 1.8 9.3 0.1 1.1 1.0 4.5 32.7 0.3 0.0 0.0 23.1 12.6 0.0 0.0 2.7 14.5 0.0 0.0 41.2 0.0 0.1 0.1 0.1 29.2 9.6 5.0 0.1 4.0 28.0 0.4 4.8 43.3 3.5 139.4 2.6 2.0 16.1 157.9 5.0 3.7 2.8 2.9 32.1 8.3 4.1 20.0 6.7 7.0 7.6 7.7 6.6 7.2 8.0 7.1 7.6 7.8 7.3 8.0 68.8 12.8 15.0 6.5 127.5 43.6 63.3 126.0 30.1 1.2 3.8 10.0 3.9 30.0 32.9 14.7 0.0 0.4 7.3 1.5 0.0 68.4 9.0 1.3 2.4 61.5 1.2 5.2 0.9 29.7 3.2 37.9 11.7 3.3 3.8 0.6 55.3 17.0 40.5 0.0 0.9 6.2 14.2 13.0 191.4 14.6 25.7 48.1 28.4 12.2 242.0 9.0 6.2 0.5 0.2 37.9 8.8 22.6 25.1 130.2 6.1 4.3 12.2 0.4 32.9 28.0 31.6 1.9 5.7 13.2 34.1 0.4 4.8 2.3 6.8 64.4 CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 8 "T-cells: 76.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cell line enriched" "Detected in some" 15 "MOLT-4: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" 0.8 0.3 0.1 7.9 0.0 1.9 1.1 0.2 0.2 0.9 0.2 1.9 1.8 0.3 0.2 1.0 0.4 2.0 0.2 0.1 0.2 0.4 1.0 2.4 15.5 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.8 3.1 0.0 0.6 0.3 0.1 0.6 3.8 0.6 0.0 4.9 2.0 0.3 0.1 15.5 0.5 0.2 14.8 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.3 26.3 0.1 64.1 0.1 80.5 11.7 0.2 0.0 76.1 0.7 1.3 0.8 0.1 0.1 10.5 13.6 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.0 2.4 0.0 2.4 1.3 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.6 2.6 0.0 1.3 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 4.0 8.9 0.0 2.9 1.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.1 2.0 0.0 76.6 0.0 0.0 0.1 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD55 "CR, CROM, DAF, TC" ENSG00000196352 "CD55 molecule (Cromer blood group)" P08174 1 207321532-207386804 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 2227.6;Syncytiotrophoblasts: 847.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 662.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 472.3;HMC-1: 665.7;PC-3: 395.0;U-2197: 405.3" "Low region specificity" "Detected in many" "HPA002190, CAB010454, HPA024386" Enhanced "Secreted to blood" NA No 32300000 360000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "CAB010454: AB_2075970, HPA002190: AB_1078472, HPA024386: AB_1846319" "unprognostic (4.08e-2)" "unprognostic (3.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.63e-1)" "unprognostic (9.05e-2)" "unprognostic (1.08e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "unprognostic (1.55e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (3.41e-2)" "unprognostic (2.04e-1)" "unprognostic (9.70e-2)" "unprognostic (2.33e-2)" 64.9 161.5 13.8 99.6 23.3 134.0 59.0 15.8 28.3 103.3 19.0 47.7 47.7 58.3 17.3 58.3 28.0 49.4 48.4 15.7 29.4 20.5 28.0 224.1 26.7 21.1 20.0 67.7 24.5 28.9 26.3 92.5 26.2 16.1 42.9 9.2 126.1 18.1 108.9 85.9 50.7 46.6 15.2 43.1 44.0 36.0 20.8 15.8 47.6 59.5 41.3 183.2 41.8 34.4 33.2 43.6 0.1 14.6 54.2 55.1 220.7 62.5 100.1 31.3 33.1 139.5 44.3 60.8 50.3 35.8 123.3 17.4 65.2 12.9 29.1 29.0 26.4 79.9 472.3 23.3 162.3 50.5 665.7 25.9 150.5 40.8 171.8 133.8 169.7 9.6 89.6 29.3 19.4 35.6 5.3 37.8 43.2 78.9 395.0 7.4 42.3 50.7 54.3 30.7 17.7 0.4 321.2 64.3 53.9 95.1 54.4 41.5 80.4 17.6 33.2 405.3 23.8 24.7 31.4 42.7 44.8 19.6 78.9 317.7 181.2 247.6 35.0 174.4 51.8 108.2 46.0 36.4 121.7 115.2 102.6 101.9 662.2 134.5 223.7 64.8 34.6 159.3 13.8 23.3 15.8 28.3 15.7 29.4 21.1 20.0 26.2 15.2 20.8 34.4 95.9 2227.6 405.3 2.3 529.8 705.1 214.1 143.6 59.2 3.1 69.9 53.8 72.7 7.2 542.6 23.9 0.0 217.5 201.7 196.1 3.9 98.6 324.6 345.6 101.9 143.4 17.3 79.8 7.6 180.2 411.7 244.7 387.9 709.3 146.9 88.9 46.8 9.1 70.0 1.7 10.7 155.7 77.3 177.5 449.2 66.3 32.6 377.3 160.1 7.5 122.6 4.8 69.0 6.0 54.3 388.9 241.2 9.1 305.4 334.9 138.4 3.2 259.5 3.3 6.6 56.1 98.0 8.9 13.7 273.4 765.9 847.7 215.4 281.5 145.1 578.6 CD5L "API6, Spalpha" ENSG00000073754 "CD5 molecule like" O43866 1 157830911-157898256 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 572.9" "Group enriched" "Detected in some" 36 "Hofbauer cells: 279.0;Kupffer cells: 567.0" "Cancer enriched" "Detected in some" 5 "liver cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA065686, HPA068384" Enhanced "Secreted to blood" NA NA 4030000000 4300000000 "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA065686: AB_2685532, HPA068384: AB_2685979" "unprognostic (2.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.73e-2)" "unprognostic (4.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.56e-1)" "unprognostic (5.95e-3)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" "unprognostic (3.63e-1)" 1.4 0.0 0.0 1.5 0.0 17.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 104.7 1.6 9.2 0.2 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 572.9 0.5 0.1 0.1 6.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 6.1 6.1 279.0 0.0 0.0 0.0 0.0 567.0 0.0 1.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.3 0.3 0.0 0.0 0.0 CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.6;lymphoid tissue: 43.1" "Cell type enhanced" "Detected in many" "dendritic cells: 25.7;NK-cells: 49.4;Plasma cells: 18.5;T-cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 33 "gdT-cell: 27.7;MAIT T-cell: 24.7;memory CD4 T-cell: 51.4;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.4;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 51 "T-cells: 51.4" "Group enriched" "Detected in some" 12 "JURKAT: 10.2;MOLT-4: 39.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" NA NA 5270000 160000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" 1.4 0.9 1.5 21.9 0.9 11.3 1.2 0.5 1.1 1.3 0.7 3.2 4.0 0.9 0.7 1.8 1.4 3.9 0.5 0.6 1.7 1.0 1.4 6.6 43.1 1.5 2.0 0.9 0.6 0.2 0.4 0.3 1.7 1.1 3.1 0.2 3.2 0.4 0.8 1.3 13.6 0.7 0.9 18.0 6.6 0.7 2.5 39.6 1.4 0.3 29.0 4.8 1.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.2 0.0 0.0 0.0 39.2 0.1 0.2 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.4 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.7 0.0 24.7 1.0 51.4 48.4 0.3 0.9 34.4 25.2 0.7 0.2 0.0 0.0 25.5 13.8 1.5 0.9 0.5 1.1 0.6 1.7 1.5 2.0 1.7 0.9 2.5 0.9 3.2 0.0 2.5 0.3 10.8 2.0 0.2 0.1 0.0 1.4 0.9 0.8 2.6 1.5 0.1 0.0 0.0 0.2 25.7 0.2 0.0 0.2 0.9 0.4 0.3 1.2 0.0 0.0 0.8 0.6 0.2 1.5 8.2 0.3 0.0 0.1 2.5 0.8 2.0 1.7 0.9 0.0 0.0 1.9 4.4 0.4 0.3 3.4 3.6 1.0 2.4 0.0 49.4 0.0 0.2 0.7 0.2 0.0 18.5 0.0 0.1 0.2 0.1 0.2 0.0 1.0 0.9 0.4 0.9 1.0 1.4 0.3 107.3 0.7 0.5 0.4 CDCP2 ENSG00000157211 "CUB domain containing protein 2" Q5VXM1 1 54132968-54153770 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA031143 Uncertain "Secreted - unknown location" NA NA "HPA031143: AB_10611819" "unprognostic (1.08e-1)" "unprognostic (5.16e-2)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-2)" "unprognostic (4.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.86e-2)" "unprognostic (2.57e-1)" "unprognostic (1.33e-1)" "unprognostic (1.67e-2)" "unprognostic (7.67e-6)" "unprognostic (2.37e-1)" "unprognostic (1.48e-1)" "unprognostic (5.12e-1)" "unprognostic (2.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDNF ARMETL1 ENSG00000185267 "Cerebral dopamine neurotrophic factor" Q49AH0 10 14819245-14838575 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 25.9;tongue: 20.3" "Group enriched" "Detected in many" 9 "Early spermatids: 99.9;Late spermatids: 274.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "RPMI-8226: 8.4;U-266/70: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044587 Uncertain "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA044587: AB_10795881" "unprognostic (2.80e-3)" "unprognostic (2.51e-2)" "unprognostic (6.20e-2)" "unprognostic (2.62e-1)" "unprognostic (4.47e-2)" "unprognostic (2.62e-1)" "unprognostic (5.32e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (4.14e-2)" "unprognostic (1.25e-1)" "unprognostic (4.81e-2)" "unprognostic (1.08e-1)" "unprognostic (8.66e-2)" "unprognostic (6.93e-2)" "unprognostic (2.31e-2)" "unprognostic (3.62e-1)" 2.5 2.4 0.8 0.5 1.1 0.4 3.6 1.2 1.2 1.7 1.3 1.2 1.8 2.0 3.8 1.5 3.9 1.5 2.2 0.9 1.3 3.4 8.6 1.1 1.5 1.2 1.3 2.8 5.4 2.9 2.0 0.5 1.4 2.9 1.1 1.7 3.8 1.8 25.9 5.0 1.1 0.7 1.3 1.0 2.5 10.1 1.0 1.2 4.1 20.3 1.5 1.2 1.3 1.7 0.4 0.4 1.0 0.4 2.2 1.9 0.1 0.8 1.7 0.7 0.5 0.6 0.9 3.3 0.7 0.5 0.0 0.3 0.1 0.0 0.7 0.3 1.0 0.5 0.5 0.2 1.4 0.2 0.0 1.7 1.2 0.3 1.3 1.1 0.7 1.5 1.0 2.1 1.0 0.9 0.4 0.3 0.6 0.6 0.2 0.6 0.4 8.4 0.4 0.1 0.8 1.3 0.2 0.5 1.4 0.5 1.2 0.3 0.5 0.1 0.3 1.4 0.1 4.5 1.2 0.5 0.6 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.3 0.3 0.5 0.3 0.3 1.2 0.8 0.0 0.9 0.1 0.4 1.6 0.2 0.8 1.1 1.2 1.2 0.9 1.3 1.2 1.3 1.4 1.3 1.0 1.7 0.5 0.0 2.2 2.0 2.3 2.0 1.4 0.7 4.0 1.0 2.3 2.2 2.0 2.8 2.3 0.0 2.1 0.9 0.6 0.1 3.9 1.0 99.9 4.2 0.8 0.9 0.0 0.4 1.0 3.6 1.6 2.1 5.1 0.6 0.0 0.7 0.4 5.8 0.4 0.0 1.4 0.5 2.0 1.2 0.6 274.2 1.2 0.4 0.0 1.0 0.2 3.1 3.1 1.5 3.3 0.6 0.5 1.2 4.8 0.9 1.4 5.2 5.8 1.0 0.0 3.2 1.8 18.9 7.5 1.6 0.1 1.4 1.2 0.5 0.7 1.2 CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115087-31120446 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "skin 1: 696.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 2.6;Gastric mucus-secreting cells: 2.0;Glandular and luminal cells: 7.1;granulocytes: 4.5;Suprabasal keratinocytes: 5.3" "Group enriched" "Detected in some" 8 "head and neck cancer: 2.4;melanoma: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "A-431: 1.6" "Region enhanced" "Detected in some" "cerebral cortex: 1.5" "Not detected" "Not detected" "HPA044730, HPA054184" Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA044730: AB_10964923, HPA054184: AB_2682409" "unprognostic (1.46e-1)" "unprognostic (6.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (8.80e-2)" "unprognostic (8.13e-2)" "unprognostic (3.92e-4)" "unprognostic (3.92e-3)" "unprognostic (1.74e-4)" "unprognostic (6.34e-2)" "unprognostic (2.75e-1)" "unprognostic (2.22e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.1 0.0 0.1 3.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 696.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 0.4 2.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 7.1 4.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.2 CEACAM16 DFNA4B ENSG00000213892 "CEA cell adhesion molecule 16, tectorial membrane component" Q2WEN9 19 44699151-44710718 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pancreas: 2.0" "Group enriched" "Detected in some" 7 "Bipolar cells: 7.7;Skeletal myocytes: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045075 Uncertain "Secreted in other tissues" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA045075: AB_10959617" "unprognostic (1.27e-1)" "unprognostic (3.73e-1)" "unprognostic (3.12e-1)" "unprognostic (3.32e-2)" "unprognostic (4.72e-1)" "unprognostic (1.42e-2)" "unprognostic (7.76e-2)" "unprognostic (3.59e-2)" "unprognostic (7.81e-3)" "unprognostic (3.88e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (7.94e-2)" 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 20.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 CEL "BSSL, MODY8" ENSG00000170835 "Carboxyl ester lipase" P19835 9 133061981-133071861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 548 "pancreas: 110578.0" "Group enriched" "Detected in many" 10 "Breast glandular cells: 390.7;Exocrine glandular cells: 943.6" "Cancer enriched" "Detected in many" 29 "pancreatic cancer: 469.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "JURKAT: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008023, HPA052701" Enhanced "Secreted to digestive system" NA NA 110000 "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA008023: AB_1846509, HPA052701: AB_2681921" "prognostic unfavorable (4.14e-4)" "unprognostic (2.30e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-2)" "unprognostic (2.22e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (6.27e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-3)" "unprognostic (2.98e-1)" "unprognostic (4.41e-1)" "unprognostic (4.37e-2)" "unprognostic (1.02e-1)" 10.0 3.0 3.1 2.2 3.2 0.9 10.4 4.8 4.5 6.4 13.5 2.9 21.6 3.2 200.8 7.1 11.1 0.4 22.0 4.1 2.7 7.5 6.4 2.1 4.1 2.9 2.8 57.2 110578.0 0.3 201.7 7.1 3.0 5.1 1.3 1.1 19.9 3.3 2.2 5.5 9.2 0.5 2.5 3.4 18.5 2.5 3.0 1.9 2.5 0.4 0.6 3.4 3.4 3.0 0.3 0.8 3.1 1.9 1.0 0.7 3.1 0.6 0.3 0.4 0.6 0.9 0.6 0.9 1.5 0.6 0.5 2.2 0.7 5.9 0.2 1.9 1.2 1.6 0.5 2.1 0.4 0.7 5.9 1.5 3.8 0.5 0.3 1.3 0.6 7.5 1.0 0.8 0.5 1.3 0.9 3.2 5.2 0.7 1.0 1.8 0.9 0.7 0.4 2.7 5.3 1.3 0.7 0.7 0.3 4.5 1.0 2.9 0.4 1.5 2.0 1.7 0.4 0.4 3.4 0.7 0.0 1.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.2 4.8 4.5 4.1 2.7 2.9 2.8 3.0 2.5 3.0 3.0 1.5 0.0 0.0 1.0 0.7 0.0 1.7 0.8 1.2 1.0 390.7 4.4 2.1 1.5 0.5 0.0 0.0 0.1 1.8 2.5 3.9 1.7 0.5 62.4 0.8 0.9 0.0 0.0 2.0 943.6 0.1 0.4 0.0 1.3 0.0 4.7 0.0 0.1 0.0 0.0 1.4 0.8 26.4 0.0 0.3 3.6 0.3 1.0 0.0 0.0 6.7 0.9 0.0 1.0 0.7 27.7 0.1 0.0 0.0 0.4 10.6 0.1 2.3 0.8 0.0 0.2 1.4 0.2 0.1 2.0 0.3 0.4 0.5 6.0 5.1 3.0 CELA1 ELA1 ENSG00000139610 "Chymotrypsin like elastase 1" Q9UNI1 12 51328442-51346679 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 2.2;pancreas: 6.6" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 16.6;Extravillous trophoblasts: 2.9;Kupffer cells: 7.9;NK-cells: 3.1" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 12.4;naive CD4 T-cell: 12.3" "Group enriched" "Detected in many" 8 "granulocytes: 12.4;T-cells: 12.3" "Cell line enriched" "Detected in some" 4 "BEWO: 5.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 28: BEWO - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (3.54e-2)" "unprognostic (1.64e-1)" "unprognostic (4.73e-2)" "unprognostic (2.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (3.59e-2)" "unprognostic (3.83e-3)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" 0.0 2.2 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 6.6 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 12.4 1.6 0.1 1.0 0.8 0.4 0.3 2.7 0.8 1.0 0.0 12.3 5.9 0.2 0.2 1.0 0.0 0.3 1.2 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 16.6 2.9 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.8 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.0 1.4 0.0 0.0 1.8 0.0 3.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.9 0.0 0.0 0.5 1.4 0.2 0.0 0.0 CELA2A ELA2A ENSG00000142615 "Chymotrypsin like elastase 2A" P08217 1 15456728-15472091 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2325 "pancreas: 162732.5" "Cell type enriched" "Detected in some" 34 "Exocrine glandular cells: 7828.2" "Cancer enriched" "Detected in single" 3818 "pancreatic cancer: 463.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HMC-1: 1.2" "Secreted to digestive system" NA NA 2700000 "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (9.78e-2)" "unprognostic (3.33e-2)" "unprognostic (5.60e-2)" "unprognostic (5.27e-2)" "unprognostic (3.63e-3)" "unprognostic (2.35e-1)" "unprognostic (4.14e-1)" "unprognostic (1.96e-2)" "unprognostic (1.38e-1)" "unprognostic (2.48e-1)" "unprognostic (3.94e-9)" "unprognostic (4.10e-2)" "unprognostic (3.42e-1)" "unprognostic (3.55e-2)" 7.9 5.5 0.0 2.6 0.0 1.1 4.4 0.2 0.1 3.9 0.0 2.0 18.5 2.1 0.0 2.3 1.1 0.0 26.9 0.0 0.0 1.6 5.8 1.2 4.3 0.0 0.0 70.0 162732.5 0.0 1.3 10.2 0.0 2.7 0.0 0.0 28.0 0.0 1.6 2.2 8.7 0.0 0.0 2.2 15.4 2.0 0.0 0.0 1.1 0.0 0.0 0.9 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.8 0.1 0.3 0.3 0.3 0.0 0.0 1.1 7828.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 20.7 0.0 0.0 0.0 0.1 227.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 CELA2B "ELA2B, RP11-265F14.2" ENSG00000215704 "Chymotrypsin like elastase 2B" P08218 1 15465909-15491395 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1672 "pancreas: 20446.9" "Cell type enriched" "Detected in some" 73 "Exocrine glandular cells: 1227.6" "Cancer enriched" "Detected in single" 574 "pancreatic cancer: 69.9" "Group enriched" "Detected in some" 4 "cerebellum: 2.0;cerebral cortex: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-138 MG: 3.9" "Secreted to digestive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 25: Pancreas - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (4.36e-3)" "unprognostic (5.45e-2)" "unprognostic (6.66e-2)" "unprognostic (5.31e-3)" "unprognostic (4.47e-3)" "unprognostic (1.37e-3)" "unprognostic (4.66e-2)" "unprognostic (6.32e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (3.85e-2)" "unprognostic (1.22e-6)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-1)" "unprognostic (7.80e-2)" 1.1 3.0 0.0 0.5 0.0 1.0 0.6 2.0 3.2 0.4 0.0 0.2 3.7 0.4 0.1 0.3 0.1 0.6 4.5 0.3 0.6 0.2 0.6 0.3 1.2 0.2 0.2 12.2 20446.9 0.0 0.1 1.2 0.0 0.3 0.0 1.7 3.4 0.0 0.3 1.0 2.4 0.0 0.0 0.3 1.2 0.7 0.4 0.0 0.8 0.0 0.0 0.1 0.1 0.3 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.5 0.8 0.4 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.2 0.3 0.6 0.2 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 1.4 1227.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.1 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase 3A" P09093 1 22001657-22012542 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2216 "pancreas: 262614.2" "Cell type enriched" "Detected in some" 56 "Exocrine glandular cells: 34710.4" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 28 "MOLT-4: 24.9" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" 20.0 4.5 0.0 3.0 0.0 2.8 11.6 0.0 0.0 12.9 0.0 4.5 21.3 4.1 0.0 7.4 3.0 0.1 44.6 0.0 0.0 4.1 13.5 3.0 6.0 0.0 0.0 118.5 262614.2 0.0 6.9 14.9 0.0 8.8 0.0 0.0 44.0 0.0 3.9 5.2 12.2 0.0 0.0 6.3 47.7 3.2 0.0 0.3 3.1 0.0 0.0 2.9 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 25.5 40.7 0.1 0.0 0.6 0.0 0.0 0.1 34710.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 197.1 0.3 2.4 0.0 0.0 94.0 0.0 0.0 0.0 0.0 619.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase 3B" P08861 1 21977022-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2088 "pancreas: 49621.1" "Cell type enriched" "Detected in some" 45 "Exocrine glandular cells: 14881.1" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" 9.0 1.8 0.0 0.6 0.0 0.8 4.5 0.0 0.0 4.4 0.0 1.8 6.2 1.6 0.1 2.6 1.2 0.0 8.4 0.0 0.0 1.6 5.0 1.2 1.1 0.0 0.0 23.7 49621.1 0.0 2.2 3.4 0.0 3.1 0.1 0.0 9.5 0.0 1.6 1.9 2.6 0.0 0.0 2.3 17.2 2.4 0.0 0.0 1.2 0.0 0.0 1.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 10.4 78.6 0.3 0.0 0.6 0.0 0.0 0.2 14881.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 309.9 0.9 0.9 0.0 0.0 60.4 0.0 0.0 0.0 0.2 325.6 16.0 0.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 CEMIP "HYBID, IR2155535, KIAA1199, TMEM2L" ENSG00000103888 "Cell migration inducing hyaluronidase 1" Q8WUJ3 15 80779343-80951776 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 25.3;endometrium 1: 31.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 62.5;Inhibitory neurons: 40.0;Microglial cells: 101.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 204.1;BJ hTERT+: 321.8;fHDF/TERT166: 258.7;HSkMC: 169.3;hTERT-RPE1: 187.6;U-138 MG: 90.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 1700000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.14e-3)" "unprognostic (6.80e-2)" "unprognostic (5.95e-2)" "unprognostic (3.15e-3)" "unprognostic (3.49e-3)" "unprognostic (6.80e-2)" "unprognostic (5.47e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (1.36e-1)" "unprognostic (5.27e-10)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.65e-4)" 5.7 1.7 1.6 11.2 8.8 1.5 0.8 5.5 11.1 13.3 25.3 1.3 0.8 31.9 6.9 6.4 6.2 2.1 1.9 2.4 3.5 0.9 0.8 15.0 9.5 3.0 1.7 4.7 1.0 1.5 8.0 2.6 2.4 2.0 1.8 4.1 1.9 1.6 0.4 5.9 1.6 0.6 5.1 1.8 0.9 2.9 4.4 0.3 3.9 0.0 4.7 14.0 2.6 3.1 0.7 7.7 1.5 1.1 0.5 2.8 0.9 204.1 321.8 5.4 4.1 2.4 1.0 1.0 0.6 258.7 0.9 4.9 0.0 0.7 1.1 0.6 1.9 0.7 1.3 17.1 1.9 0.5 1.0 169.3 0.2 39.6 0.2 187.6 0.0 1.0 1.0 0.8 4.8 4.7 0.7 0.5 1.0 68.9 9.2 1.2 0.3 0.9 0.0 3.5 12.7 0.4 3.5 0.5 17.7 2.7 1.0 0.4 1.0 90.6 0.9 6.8 3.5 0.8 0.7 1.2 9.6 1.8 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.6 8.8 5.5 11.1 2.4 3.5 3.0 1.7 2.4 5.1 4.4 3.1 0.1 0.0 1.5 2.9 0.1 0.0 0.3 0.0 11.4 2.9 0.0 0.1 1.2 0.0 4.3 0.0 6.2 0.2 0.0 1.1 0.0 0.1 1.0 0.7 4.3 1.6 4.8 0.0 62.5 0.4 0.2 4.3 0.0 7.0 1.3 0.1 0.4 0.0 0.4 3.3 40.0 0.5 0.0 0.0 0.0 0.6 0.3 0.9 0.0 101.2 0.0 0.4 0.0 6.6 8.2 0.7 0.1 0.0 0.1 2.7 0.0 0.1 0.0 3.0 0.0 0.4 0.8 0.2 0.7 1.0 0.0 0.3 0.1 0.1 0.8 0.9 CER1 DAND4 ENSG00000147869 "Cerberus 1, DAN family BMP antagonist" O95813 9 14719724-14722733 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "epididymis: 1.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 82 "testis cancer: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEL: 4.0;NTERA-2: 7.0;SCLC-21H: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA019917 Uncertain "Secreted - unknown location" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" "HPA019917: AB_1846539" "unprognostic (2.98e-2)" "unprognostic (5.36e-2)" "unprognostic (5.99e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.1 0.3 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67009758 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.9;skin 1: 13.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 44.4;Excitatory neurons: 53.6;Oligodendrocytes: 37.6;Respiratory ciliated cells: 47.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.3" "Region enhanced" "Detected in many" "white matter: 10.2" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 19.1;HMC-1: 5.2;PC-3: 4.5;SiHa: 7.8;SK-BR-3: 5.7;U-266/70: 5.9" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "HPA035701: AB_10696357" "unprognostic (6.34e-2)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (3.26e-2)" "unprognostic (1.99e-1)" "unprognostic (6.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.93e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-3)" 3.6 1.5 1.2 0.8 2.6 1.2 2.5 0.1 2.5 1.0 0.0 0.6 0.8 0.5 3.9 1.0 16.9 0.8 2.4 2.3 1.0 2.6 8.4 1.5 0.7 1.7 0.2 1.0 1.1 3.1 3.6 1.0 1.2 0.9 0.7 0.8 4.3 2.1 4.9 13.6 0.8 0.3 0.0 0.5 1.4 0.8 0.8 0.7 2.7 0.2 0.9 1.2 0.7 10.2 0.2 1.5 0.1 0.0 0.9 0.8 0.0 0.4 0.7 0.1 0.0 0.0 2.3 0.0 0.0 1.5 0.0 0.7 0.0 0.2 0.0 19.1 0.0 0.0 1.2 0.0 0.1 0.0 5.2 1.8 3.5 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 4.5 0.2 0.0 1.1 0.0 0.3 1.4 0.9 7.8 5.7 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 5.9 2.2 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.5 2.5 0.5 0.6 1.0 0.5 0.8 0.0 0.9 0.2 0.0 0.0 3.5 1.2 0.3 0.7 1.2 2.6 0.1 2.5 2.3 1.0 1.7 0.2 1.2 0.0 0.8 10.2 0.4 0.0 11.4 2.0 3.5 5.4 5.7 5.0 3.4 23.1 44.4 7.7 2.8 4.3 7.3 5.5 14.6 4.7 3.9 4.1 1.9 0.9 1.7 9.9 1.4 1.0 9.0 0.0 53.6 1.6 0.9 3.9 3.1 11.1 9.5 4.9 1.1 22.1 5.6 0.0 29.7 1.8 4.1 4.1 2.1 1.2 13.7 3.2 0.0 4.7 5.7 8.3 4.1 6.6 37.6 0.9 9.7 12.8 1.3 3.5 5.8 1.5 47.1 15.3 0.0 1.5 1.8 32.1 11.8 4.1 5.3 4.5 3.3 13.5 3.5 7.5 CES5A "CAUXIN, CES4C1, CES5, CES7, FLJ31547" ENSG00000159398 "Carboxylesterase 5A" Q6NT32 16 55846154-55956031 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "epididymis: 67.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.5;Collecting duct cells: 5.5;Excitatory neurons: 1.4;Hepatocytes: 6.9;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 4.0" "Cancer enriched" "Detected in single" 5 "liver cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 46 "U-266/70: 7.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (2.07e-1)" "unprognostic (2.55e-1)" "unprognostic (6.34e-2)" "unprognostic (4.82e-2)" "unprognostic (3.78e-1)" "unprognostic (2.33e-1)" "unprognostic (3.12e-2)" "unprognostic (1.72e-7)" "unprognostic (1.55e-2)" "unprognostic (2.27e-1)" 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 67.5 0.0 0.0 0.6 0.1 0.1 0.2 0.0 3.9 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.2 0.1 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CETP BPIFF ENSG00000087237 "Cholesteryl ester transfer protein" P11597 16 56961923-56983845 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 33.5;liver: 43.0;lymphoid tissue: 59.6;placenta: 36.2" "Group enriched" "Detected in some" 6 "Adipocytes: 48.6;Hepatic stellate cells: 75.0;Kupffer cells: 142.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.3;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 2.3;HUVEC TERT2: 4.7;TIME: 2.8" "Secreted to blood" NA NA 2470000000 360000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.52e-2)" "unprognostic (4.17e-3)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" "unprognostic (4.01e-3)" "unprognostic (4.03e-3)" "unprognostic (3.56e-2)" "unprognostic (1.41e-1)" "unprognostic (3.05e-3)" "unprognostic (4.92e-3)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" "unprognostic (7.62e-2)" "unprognostic (2.20e-2)" "unprognostic (4.08e-2)" "unprognostic (7.34e-2)" "unprognostic (9.97e-2)" 33.5 2.0 0.7 3.8 0.7 5.7 6.6 0.7 1.4 0.3 0.7 0.6 0.9 0.7 0.0 0.3 0.3 4.0 0.7 0.6 0.8 3.7 43.0 2.8 43.3 1.1 0.8 0.3 0.5 1.8 3.1 36.2 0.9 0.3 0.5 0.0 0.7 0.5 0.3 0.4 1.9 0.8 0.8 59.6 0.4 0.3 0.9 2.3 5.2 0.3 7.6 1.5 0.1 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.2 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.8 0.1 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 1.8 2.3 3.2 0.0 1.2 0.7 0.7 0.7 1.4 0.6 0.8 1.1 0.8 0.9 0.8 0.9 0.8 48.6 0.0 1.8 0.0 1.5 0.5 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 13.4 0.0 5.3 0.1 0.9 0.4 0.2 0.0 0.1 0.0 0.0 75.0 1.3 3.1 0.0 0.1 0.2 0.0 142.0 1.2 0.7 0.0 2.1 0.0 0.0 1.4 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.6 0.0 0.4 0.0 0.4 1.3 0.0 0.0 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CFC1 "CRYPTIC, HTX2" ENSG00000136698 "Cripto, FRL-1, cryptic family 1" P0CG37 2 130592165-130599575 "Disease related genes, Human disease related genes, Predicted secreted proteins" Gastrulation "Developmental protein" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.0;pancreas: 30.7;pituitary gland: 59.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 14.9;Enteroendocrine cells: 20.5" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 4.3" "Region enhanced" "Detected in all" "hypothalamus: 24.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "RPMI-8226: 12.1;SCLC-21H: 6.7;SuSa: 4.0" HPA041773 Uncertain "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA041773: AB_2677664" "unprognostic (6.65e-2)" "unprognostic (2.19e-3)" "unprognostic (1.11e-3)" "unprognostic (2.01e-1)" 1.7 0.6 4.6 0.0 2.3 0.0 0.0 2.9 3.5 0.1 0.0 0.2 0.0 0.2 0.1 0.0 1.5 0.0 1.9 1.3 24.0 0.0 0.0 0.1 0.0 3.9 8.1 0.0 30.7 0.0 59.3 0.0 5.6 7.2 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 10.7 0.6 8.6 5.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 2.3 2.9 3.5 1.3 24.0 3.9 8.1 5.6 3.9 8.6 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 20.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CFC1B ENSG00000152093 "Cripto, FRL-1, cryptic family 1B" P0CG36 2 130521197-130528604 "Predicted secreted proteins" Gastrulation "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pituitary gland: 2.4" "Cell type enriched" "Detected in single" 9 "Bipolar cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041773 Approved "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 56: Bipolar cells - Visual perception" "HPA041773: AB_2677664" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 2.4 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196832189 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 272 "liver: 2081.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 320.0" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HeLa: 1.2;HL-60: 2.0;U-266/70: 2.4" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" 1.5 0.6 0.1 1.8 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 7.6 2081.3 0.1 6.7 0.1 0.8 0.3 0.3 0.0 0.1 0.1 0.4 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.7 0.2 0.1 6.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.9 0.3 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.1 0.1 0.0 2.4 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.4 0.1 0.2 0.1 0.5 3.2 0.0 0.0 2.2 0.4 0.1 0.0 0.0 1.2 0.0 0.1 1.8 11.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 18.7 0.0 0.0 0.0 9.9 0.0 0.0 0.0 6.0 15.0 320.0 5.6 0.0 0.4 0.0 0.0 16.9 0.4 0.2 1.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 41.0 2.1 0.3 1.5 0.0 0.0 0.3 1.4 5.6 0.1 0.1 CFHR2 "CFHL2, FHR2, HFL3" ENSG00000080910 "Complement factor H related 2" P36980 1 196943738-196959622 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2752 "liver: 1311.8" "Cell type enriched" "Detected in some" 14 "Hepatocytes: 38.5" "Cancer enriched" "Detected in single" 175 "liver cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038915, HPA040726, HPA049813" Supported "Secreted to blood" NA NA 4800000000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: Hepatocytes - Hemostasis" "HPA038915: AB_2676269, HPA040726: AB_2677101, HPA049813: AB_2680895" "unprognostic (1.25e-2)" 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1311.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 38.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFHR3 "CFHL3, DOWN16, FHR-3, FHR3, HLF4" ENSG00000116785 "Complement factor H related 3" Q02985 1 196774813-196795407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 582 "liver: 505.7" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 205.5" "Cancer enriched" "Detected in single" 80 "liver cancer: 27.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;SuSa: 1.5;T-47d: 3.6;U-266/70: 6.4" "Secreted to blood" NA NA 582000000 3100000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" "unprognostic (7.16e-2)" "unprognostic (6.77e-2)" "unprognostic (4.46e-1)" "unprognostic (4.20e-3)" "prognostic favorable (2.86e-5)" "unprognostic (1.78e-1)" "unprognostic (2.05e-2)" "unprognostic (1.98e-1)" "unprognostic (1.19e-2)" "unprognostic (6.11e-3)" "unprognostic (2.06e-10)" "unprognostic (2.67e-4)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.32e-1)" 0.8 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.4 505.7 0.2 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.1 0.1 0.3 0.0 0.3 0.1 0.0 0.4 0.1 0.6 0.0 0.7 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.4 0.0 0.9 0.0 0.0 0.0 0.3 0.0 1.5 3.6 0.0 0.0 0.1 0.2 0.3 0.0 6.4 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.5 1.8 16.0 0.1 0.0 0.1 1.7 0.0 0.0 0.0 0.0 7.1 205.5 0.0 0.0 0.1 0.0 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 CFHR4 "CFHL4, FHR-4, FHR4" ENSG00000134365 "Complement factor H related 4" Q92496 1 196888014-196918713 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 432 "liver: 123.9" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 62.6" "Cancer enriched" "Detected in single" 145 "liver cancer: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 170000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (5.97e-1)" "prognostic favorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (4.79e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (4.71e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 123.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.2 62.6 0.0 0.0 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFHR5 "CFHL5, FHR-5, FHR5" ENSG00000134389 "Complement factor H related 5" Q9BXR6 1 196977556-197009678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1675 "liver: 167.5" "Cell type enriched" "Detected in some" 19 "Hepatocytes: 102.7" "Cancer enriched" "Detected in single" 396 "liver cancer: 57.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038915, HPA040726" Supported "Secreted to blood" NA NA 1900000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "HPA038915: AB_2676269, HPA040726: AB_2677101" "unprognostic (9.12e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 102.7 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 592.5;Muller glia cells: 147.8;Proximal tubular cells: 223.6" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 106.1;Hep G2: 179.8;HSkMC: 67.4;RPTEC TERT1: 190.6" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 45.1 50.2 8.1 12.6 8.2 0.1 17.4 7.7 13.2 36.8 10.4 7.4 38.0 39.2 80.3 9.3 74.0 73.0 25.0 8.3 9.6 224.9 1098.8 50.7 8.9 15.6 10.2 32.1 26.0 3.1 8.4 24.1 10.7 8.3 6.4 53.0 15.0 26.7 3.9 2.7 22.3 24.3 10.5 33.1 14.4 8.8 9.2 2.3 14.5 4.6 7.5 34.1 8.3 10.6 0.0 0.6 0.0 0.3 0.0 0.2 0.1 1.5 1.4 0.1 0.2 0.0 106.1 0.0 32.9 0.0 0.5 0.0 0.0 0.0 0.0 34.8 0.7 0.0 0.4 179.8 6.2 0.3 0.0 67.4 0.0 0.1 0.0 3.6 4.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 190.6 0.5 0.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.0 0.1 18.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 8.2 7.7 13.2 8.3 9.6 15.6 10.2 10.7 10.5 9.2 10.6 48.1 12.8 50.9 3.6 4.0 1.0 12.2 15.2 0.6 3.4 2.1 5.6 2.3 108.7 36.2 64.4 2.1 0.1 0.3 1.7 31.3 69.3 0.2 34.1 46.4 57.7 0.0 2.7 0.3 30.9 0.2 34.3 8.2 33.6 3.8 72.1 55.0 592.5 0.7 1.7 0.2 1.9 0.0 16.7 1.5 0.8 16.8 2.0 0.0 4.7 1.6 147.8 0.0 0.0 0.3 30.8 2.4 0.0 0.0 3.8 17.0 223.6 8.4 7.3 0.0 1.3 9.4 1.6 0.5 1.9 1.1 0.3 3.4 18.5 4.1 12.6 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CGA "FSHA, GPA1, GPHa, GPHA1, HCG, LHA, TSHA" ENSG00000135346 "Glycoprotein hormones, alpha polypeptide" P01215 6 87085498-87095106 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 4389.4" "Cell type enriched" "Detected in some" 15 "Syncytiotrophoblasts: 85317.2" "Cancer enhanced" "Detected in many" "breast cancer: 10.9;testis cancer: 13.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "BEWO: 776.1;SuSa: 1437.9" "Region enriched" "Detected in many" 6 "hypothalamus: 22.2" "Region enriched" "Detected in many" 40 "hypothalamus: 82.2" "CAB023350, HPA029698" Enhanced "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB023350: AB_617281, HPA029698: AB_2673153" "unprognostic (1.66e-1)" "unprognostic (2.10e-1)" "unprognostic (3.22e-5)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.69e-2)" "unprognostic (3.17e-1)" "unprognostic (7.04e-3)" "unprognostic (1.51e-1)" "unprognostic (2.85e-1)" "unprognostic (4.32e-2)" "unprognostic (8.32e-2)" "unprognostic (9.15e-3)" 0.8 4.1 0.2 0.1 0.4 1.9 0.1 0.7 0.7 0.0 0.3 0.3 0.5 1.0 1.2 1.2 0.1 0.2 1.5 0.3 0.3 2.7 2.0 0.7 0.3 2.1 1.6 0.5 1.3 18.9 4389.4 725.8 0.9 2.7 0.3 0.3 0.5 1.1 3.3 2.1 0.3 3.4 0.1 1.1 38.1 0.5 1.0 0.8 0.5 0.0 0.3 0.4 0.2 1.5 0.0 1.0 0.0 0.1 0.0 0.0 776.1 0.7 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.9 4.2 1.8 0.3 40.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.1 1.0 0.6 0.1 22.6 0.0 1437.9 0.1 0.0 0.0 0.9 0.2 0.4 0.3 3.1 0.4 0.5 0.2 0.0 0.1 0.7 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.3 0.1 0.4 0.2 0.4 0.6 0.2 0.3 0.4 0.1 0.0 0.2 0.4 0.7 0.7 0.3 0.3 2.1 1.6 0.9 0.1 1.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 1.9 0.0 0.0 7.3 0.0 1414.2 0.1 0.0 0.0 0.0 0.2 20.2 1.1 22.9 1.8 0.0 0.2 0.0 5400.7 65.5 0.0 28.4 0.0 0.0 0.0 0.0 625.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.0 85317.2 6.0 0.0 0.2 9.9 CGB1 ENSG00000267631 "Chorionic gonadotropin subunit beta 1" A6NKQ9 19 49035569-49036895 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "pancreas: 2.7;pituitary gland: 4.3" "Cell type enriched" "Detected in single" 77 "Syncytiotrophoblasts: 69.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HMC-1: 17.7" "HPA038925, HPA038934" Uncertain Approved Cytosol "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 3.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 69.9 0.0 0.0 0.0 0.0 CGB2 ENSG00000104818 "Chorionic gonadotropin subunit beta 2" Q6NT52 19 49031890-49033238 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.6" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 40.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HMC-1: 29.9;U-266/70: 12.1;U-266/84: 15.6" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (3.05e-2)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.5 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.8 0.7 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 4.1 0.0 0.5 0.0 0.1 0.3 0.0 29.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.8 0.0 3.9 12.1 15.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.2 0.2 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1.5 1.8 0.0 0.0 40.0 0.0 0.0 0.0 0.0 CGB3 CGB ENSG00000104827 "Chorionic gonadotropin subunit beta 3" P0DN86 19 49022869-49024333 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 9.8" "Cell type enriched" "Detected in some" 7 "Syncytiotrophoblasts: 865.9" "Group enriched" "Detected in some" 5 "pancreatic cancer: 2.9;testis cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "BEWO: 65.8" "CAB000042, CAB010884, HPA038925, HPA038934" Enhanced Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB000042: , CAB010884: AB_259037, HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (1.39e-1)" "unprognostic (7.88e-2)" "unprognostic (6.92e-2)" "unprognostic (1.04e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 2.1 9.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.0 65.8 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.2 0.1 0.0 0.1 0.0 0.0 1.4 0.6 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.2 0.3 0.0 0.3 0.2 0.1 0.4 0.0 0.0 2.1 0.7 0.0 0.0 0.1 0.4 0.0 3.3 1.3 0.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 118.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 865.9 0.0 0.0 0.0 0.0 CGB5 HCG ENSG00000189052 "Chorionic gonadotropin subunit beta 5" P0DN86 19 49043848-49045311 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pituitary gland: 8.7;placenta: 25.6" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 19.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 10.0;testis cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "BEWO: 120.1;U-251 MG: 53.2" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (1.38e-1)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "prognostic unfavorable (1.18e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.47e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 8.7 25.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.4 0.0 0.0 0.0 0.0 120.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.2 0.0 53.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 CGB7 CG-beta-a ENSG00000196337 "Chorionic gonadotropin subunit beta 7" P0DN87 19 49054275-49058860 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 3.2;skin 1: 3.9" "Group enriched" "Detected in some" 5 "Pancreatic endocrine cells: 16.5;Syncytiotrophoblasts: 58.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;HaCaT: 3.1;hTCEpi: 3.2;U-251 MG: 7.5" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (9.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-1)" "unprognostic (3.53e-1)" "unprognostic (4.60e-5)" "unprognostic (2.64e-1)" "unprognostic (2.46e-1)" "unprognostic (8.37e-2)" "unprognostic (2.88e-2)" "unprognostic (4.80e-2)" "unprognostic (8.83e-4)" "unprognostic (1.54e-1)" "unprognostic (3.89e-8)" "unprognostic (1.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-1)" "unprognostic (9.28e-2)" 0.1 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.3 1.1 0.2 0.0 0.1 0.1 0.1 2.4 0.6 0.0 0.1 0.2 0.1 0.2 0.0 0.6 0.0 0.1 0.3 0.1 0.7 0.0 1.5 0.4 0.1 3.2 0.0 0.0 1.1 0.4 2.2 3.9 0.0 0.0 0.1 0.1 0.0 1.1 0.1 0.2 0.2 0.1 0.0 1.1 1.8 0.1 2.2 0.3 0.1 1.0 0.0 0.0 2.7 0.3 0.0 0.6 0.8 0.5 1.8 0.0 0.1 0.5 1.2 3.1 0.0 2.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 3.2 0.2 0.4 1.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 1.0 0.0 0.0 1.1 0.6 0.1 0.0 1.5 1.5 0.0 7.5 0.2 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.6 0.1 0.6 1.8 0.0 0.1 0.3 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 1.2 0.4 0.3 0.0 58.7 0.0 0.0 0.0 0.1 CGB8 ENSG00000213030 "Chorionic gonadotropin subunit beta 8" P0DN86 19 49047638-49049106 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "placenta: 18.8" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 44.3" "Cancer enriched" "Detected in some" 4 "testis cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 157.9;U-251 MG: 57.2" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (7.44e-3)" "unprognostic (4.70e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 18.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 1.2 0.0 0.0 0.0 0.0 157.9 0.0 0.0 0.6 0.0 0.0 5.3 0.0 0.1 1.0 4.0 1.3 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 10.1 0.2 0.6 0.0 2.8 7.1 0.7 57.2 0.1 0.2 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.3 0.0 0.0 0.0 0.0 CGREF1 CGR11 ENSG00000138028 "Cell growth regulator with EF-hand domain 1" Q99674 2 27098889-27119128 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.3;salivary gland: 25.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.6;Excitatory neurons: 16.6;Inhibitory neurons: 15.9;Oligodendrocyte precursor cells: 12.5;Spermatogonia: 16.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 40.1;SK-BR-3: 78.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008241, HPA071103" Uncertain Approved "Golgi apparatus" "Secreted in brain" NA NA 700000 "Cluster 65: Brain - Ion transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA008241: AB_1846605, HPA071103: " "unprognostic (1.39e-2)" "unprognostic (1.26e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (8.45e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (5.22e-2)" "unprognostic (7.34e-2)" "unprognostic (1.92e-1)" "unprognostic (2.57e-1)" "unprognostic (2.27e-1)" "unprognostic (2.52e-3)" "unprognostic (1.05e-1)" "unprognostic (2.30e-2)" "unprognostic (7.24e-4)" "unprognostic (1.20e-2)" 4.2 2.3 20.4 1.0 21.7 1.9 6.3 17.1 28.3 3.5 2.1 2.6 3.9 11.6 1.4 3.5 12.4 3.9 4.9 27.0 18.1 3.8 14.9 1.1 0.5 12.8 12.1 13.9 2.1 0.2 3.3 0.3 12.8 4.2 3.8 3.7 25.3 0.9 6.5 2.3 5.6 5.4 10.2 0.6 11.4 3.8 17.2 0.2 1.8 6.9 0.4 3.7 1.5 16.4 7.6 6.3 0.3 8.1 18.3 6.8 0.7 9.1 0.0 0.8 0.4 1.7 6.2 0.1 2.4 18.2 2.2 0.4 1.4 2.1 0.5 0.7 3.7 0.1 10.4 16.4 16.9 5.3 0.6 4.7 18.1 2.6 2.1 11.6 0.7 1.3 0.2 0.4 1.2 24.0 4.0 6.8 2.1 40.1 16.8 0.3 0.0 0.6 0.1 0.3 17.8 26.6 17.7 78.7 9.4 0.2 25.3 13.3 0.0 0.0 6.9 0.0 0.7 2.3 0.8 0.7 0.0 0.2 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.7 17.1 28.3 27.0 18.1 12.8 12.1 12.8 10.2 17.2 16.4 0.1 0.0 0.0 2.6 0.4 0.6 0.2 0.0 1.8 9.2 9.2 12.6 1.4 0.0 0.0 0.0 4.2 0.0 0.1 0.2 0.0 0.1 1.1 0.3 3.0 0.4 0.0 5.5 16.6 1.5 0.2 3.8 4.6 0.1 0.0 0.4 3.6 5.0 0.4 0.0 15.9 6.8 0.0 0.6 0.7 3.1 4.4 0.2 0.0 1.9 0.0 0.5 0.0 12.5 0.8 2.1 0.0 8.6 1.1 1.8 3.4 4.4 0.0 2.2 0.0 1.7 0.7 3.2 16.2 2.2 0.4 0.1 0.1 3.2 0.9 0.1 CHAD SLRR4A ENSG00000136457 Chondroadherin O15335 17 50464496-50468906 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.2;pancreas: 32.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.6;Breast myoepithelial cells: 2.4;Distal enterocytes: 3.3;Gastric mucus-secreting cells: 4.6;Hepatocytes: 2.4;Intestinal goblet cells: 4.3;Oligodendrocyte precursor cells: 5.5;Paneth cells: 2.5;Proximal enterocytes: 2.6" "Group enriched" "Detected in many" 5 "breast cancer: 23.7;liver cancer: 10.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "memory B-cell: 21.5;naive B-cell: 8.0" "Lineage enriched" "Detected in single" 76 "B-cells: 21.5" "Cell line enhanced" "Detected in some" "RT4: 4.0;SCLC-21H: 8.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018241 Enhanced "Secreted to extracellular matrix" NA NA 22000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA018241: AB_1846612" "prognostic favorable (7.68e-4)" "unprognostic (4.34e-2)" "unprognostic (1.24e-1)" "unprognostic (9.67e-3)" "unprognostic (1.92e-1)" "unprognostic (3.06e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.51e-2)" "unprognostic (4.75e-2)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-2)" "unprognostic (1.51e-3)" "unprognostic (1.41e-3)" 2.1 14.1 6.2 0.7 7.9 0.3 9.6 17.4 7.3 21.8 3.9 6.7 7.6 0.5 0.1 1.8 0.8 1.5 1.7 5.5 6.3 2.4 36.2 1.6 0.6 5.6 4.9 3.1 32.6 0.0 1.3 0.5 5.7 1.9 4.0 0.5 21.3 0.2 14.5 8.5 10.3 0.1 5.1 1.1 10.8 1.2 5.8 0.2 4.2 0.9 0.2 1.2 1.6 5.4 1.0 0.8 0.7 0.6 0.0 0.0 2.1 0.1 0.0 0.0 0.0 1.5 0.8 0.1 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.6 0.7 1.2 0.7 1.5 0.0 0.4 1.1 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.1 0.7 0.9 0.1 1.5 0.0 4.0 8.5 0.2 0.1 0.3 0.0 0.3 0.3 0.2 0.9 2.1 0.4 0.1 0.0 1.4 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 6.2 7.9 17.4 7.3 5.5 6.3 5.6 4.9 5.7 5.1 5.8 5.4 0.0 0.0 0.0 1.3 1.0 0.3 0.2 0.3 0.0 0.0 4.6 2.4 0.2 1.5 0.2 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.2 4.3 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.5 0.1 0.0 2.5 0.0 1.1 0.2 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.4 CHADL SLRR4B ENSG00000100399 "Chondroadherin like" Q6NUI6 22 41229510-41240931 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 109.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 40.3;Oligodendrocytes: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 11.8;Hep G2: 3.4;hTCEpi: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005696, HPA024654" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "HPA005696: AB_1079724, HPA024654: AB_1846615" "unprognostic (6.14e-2)" "unprognostic (4.42e-3)" "unprognostic (1.49e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (9.51e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.56e-4)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (2.83e-3)" "unprognostic (1.51e-2)" "unprognostic (4.67e-8)" "unprognostic (8.36e-3)" "unprognostic (4.10e-1)" "unprognostic (3.40e-1)" "unprognostic (4.09e-2)" 2.6 4.7 25.4 0.5 62.4 1.0 2.6 57.5 43.9 3.5 5.2 12.4 1.5 1.3 1.5 4.2 2.2 2.7 16.5 25.1 32.4 2.1 3.1 2.1 0.8 69.6 51.8 2.6 3.5 0.5 4.3 0.6 61.3 6.5 0.3 1.0 11.3 3.8 2.2 6.1 3.4 0.8 43.4 0.7 5.0 3.5 56.3 1.7 4.4 1.6 0.4 2.9 3.6 109.6 0.6 0.2 0.2 0.3 0.1 0.1 11.8 0.4 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.6 0.1 0.5 0.0 0.6 0.0 0.1 0.2 0.0 0.3 3.4 0.4 0.1 0.1 1.0 3.4 0.3 0.0 0.1 0.4 0.2 0.0 0.5 0.0 0.3 0.2 0.6 0.3 0.3 0.4 0.1 0.5 0.2 0.2 0.3 0.7 0.1 1.3 0.2 0.1 0.0 0.0 1.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.1 1.6 0.0 0.1 0.4 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.0 0.4 0.1 0.2 0.0 0.0 1.2 0.0 0.3 25.4 62.4 57.5 43.9 25.1 32.4 69.6 51.8 61.3 43.4 56.3 109.6 2.7 6.4 2.2 8.1 0.2 4.0 10.2 1.8 17.6 1.4 7.3 6.5 3.5 2.8 1.7 3.7 0.0 3.0 0.4 0.8 7.9 2.0 18.6 2.5 0.6 1.3 3.0 0.0 2.8 1.2 6.4 5.5 2.6 1.6 0.0 3.2 2.5 2.5 5.1 0.0 2.5 0.8 2.0 0.8 2.1 12.0 3.7 3.4 17.8 1.9 0.4 40.3 0.0 12.5 83.1 0.8 1.0 3.0 0.3 3.7 1.3 5.9 4.1 1.6 0.0 2.5 1.2 0.3 0.8 6.5 3.7 1.5 0.5 0.7 1.4 6.5 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHI3L2 "YKL-39, YKL39" ENSG00000064886 "Chitinase 3 like 2" Q15782 1 111200771-111243440 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 200.6;salivary gland: 142.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 118.1;B-cells: 76.4;Breast glandular cells: 32.2;Breast myoepithelial cells: 30.4;Leydig cells: 74.9" "Cancer enriched" "Detected in many" 8 "glioma: 104.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 91.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "JURKAT: 634.6;MOLT-4: 346.8" "Low region specificity" "Detected in all" HPA005443 Approved "Secreted to blood" NA NA 420000 "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA005443: AB_1078510" "unprognostic (1.02e-2)" "unprognostic (4.34e-2)" "unprognostic (1.37e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (9.10e-5)" "prognostic favorable (2.19e-4)" "unprognostic (7.12e-2)" "unprognostic (1.39e-1)" "unprognostic (1.49e-3)" "unprognostic (1.26e-2)" "unprognostic (1.32e-2)" "unprognostic (2.44e-2)" "prognostic unfavorable (8.59e-7)" "unprognostic (7.15e-3)" "unprognostic (7.68e-2)" "unprognostic (1.39e-3)" "unprognostic (1.20e-1)" 22.1 3.0 12.4 112.7 12.0 2.4 44.6 9.2 41.6 1.0 10.9 3.2 1.2 1.7 0.2 5.1 2.2 11.8 23.0 12.3 13.6 3.1 0.9 66.1 59.8 63.7 34.7 2.1 0.8 36.6 4.5 13.7 27.1 7.4 2.6 1.7 142.1 0.7 2.0 11.3 10.0 3.7 18.6 21.5 5.9 11.7 34.5 200.6 11.8 7.5 119.0 53.5 4.5 26.4 0.3 0.0 0.4 0.5 100.3 19.1 0.2 0.1 1.3 0.2 0.2 0.0 0.3 0.8 0.2 0.1 8.8 0.6 3.5 0.2 0.1 29.0 0.1 0.2 0.5 1.6 1.5 0.2 1.7 27.9 0.3 0.4 0.5 5.5 0.0 634.6 0.2 1.2 0.3 0.2 346.8 0.5 0.0 0.1 0.1 1.8 0.9 0.6 0.0 0.7 0.1 0.3 0.4 0.9 0.3 2.1 0.3 0.3 0.5 7.5 1.4 0.2 0.7 5.2 0.6 76.8 23.4 0.5 2.3 1.0 3.6 0.2 22.4 0.8 5.5 45.0 16.0 37.5 0.8 43.2 91.6 34.4 2.2 17.2 0.3 1.4 10.8 27.3 12.4 12.0 9.2 41.6 12.3 13.6 63.7 34.7 27.1 18.6 34.5 26.4 0.5 9.6 118.1 1.0 76.4 2.3 1.6 8.3 0.0 0.1 32.2 30.4 0.5 0.0 3.1 0.0 0.0 0.2 7.8 0.1 0.0 20.1 3.8 0.3 7.0 0.9 1.2 0.0 0.2 0.4 0.9 10.8 0.0 0.7 2.5 0.0 0.4 0.0 1.1 0.0 0.1 0.0 0.0 2.2 0.7 12.0 74.9 2.2 16.0 0.0 0.8 0.0 23.7 0.0 0.3 0.9 0.0 1.5 2.6 3.5 0.0 0.5 0.2 0.0 0.0 1.8 0.7 0.5 0.6 0.3 1.3 3.1 12.8 1.5 0.0 1.3 CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.8;lung: 36.4;lymphoid tissue: 21.7" "Cell type enriched" "Detected in some" 10 "Hofbauer cells: 40.6" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Region enriched" "Detected in some" 6 "cerebral cortex: 12.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010575, HPA074844" Enhanced "Secreted to blood" NA NA 26400000 57000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Macrophages - Innate immune response" "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favorable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" 13.6 0.3 0.2 0.4 0.2 49.8 8.3 0.0 12.4 8.1 0.0 1.2 0.0 3.6 0.1 0.0 0.1 0.4 0.2 0.2 0.0 0.1 0.7 36.4 21.7 0.4 0.2 0.5 2.1 0.0 0.0 0.7 1.3 1.0 1.0 0.0 0.4 0.0 0.2 0.4 0.8 0.0 0.4 5.7 0.5 0.0 0.3 3.4 1.3 0.0 1.1 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.2 0.2 0.0 12.4 0.2 0.0 0.4 0.2 1.3 0.4 0.3 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 40.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 CHL1 "CALL, FLJ44930, L1CAM2, MGC132578" ENSG00000134121 "Cell adhesion molecule L1 like" O00533 3 196763-409417 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Astrocytes: 223.6;Excitatory neurons: 423.8;Inhibitory neurons: 320.7;Oligodendrocyte precursor cells: 918.4" "Cancer enhanced" "Detected in many" "glioma: 15.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 2.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 38 "B-cells: 3.7" "Group enriched" "Detected in some" 5 "SK-MEL-30: 91.8;WM-115: 29.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003345, CAB026120" Enhanced "Secreted in brain" NA NA 5800000000 "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB026120: , HPA003345: AB_1078516" "unprognostic (5.54e-2)" "unprognostic (2.08e-1)" "unprognostic (7.45e-2)" "unprognostic (7.14e-3)" "unprognostic (1.16e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-2)" "unprognostic (2.22e-1)" "unprognostic (5.14e-1)" "unprognostic (1.06e-1)" "unprognostic (7.81e-2)" "unprognostic (3.51e-1)" "prognostic favorable (1.21e-6)" "unprognostic (1.11e-1)" "unprognostic (6.07e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" 13.6 4.1 18.6 8.6 33.9 0.3 8.5 2.3 35.5 3.3 0.0 14.7 4.4 3.4 1.6 8.9 2.6 4.8 11.5 35.8 26.7 17.8 0.8 5.1 6.2 12.5 5.3 16.3 1.7 0.5 2.6 0.0 5.7 3.7 7.9 15.9 6.9 6.3 0.3 12.9 6.2 5.4 10.0 3.0 4.0 1.5 10.6 0.7 0.9 1.4 2.9 3.1 5.3 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 33.9 2.3 35.5 35.8 26.7 12.5 5.3 5.7 10.0 10.6 5.0 4.1 0.0 0.0 223.6 8.8 22.9 0.6 2.8 56.9 1.2 0.6 13.6 18.0 1.5 15.8 11.0 0.0 0.0 0.1 0.0 11.7 0.0 2.0 2.9 0.1 2.3 0.0 0.0 423.8 0.0 0.0 33.5 0.0 1.9 1.3 106.2 1.4 1.3 0.0 1.7 320.7 0.0 0.0 0.3 4.4 1.4 2.8 0.6 3.6 22.5 0.0 58.7 0.0 918.4 11.6 0.2 0.0 0.0 1.4 6.2 0.0 19.7 17.8 2.7 0.0 2.7 11.2 3.0 1.3 15.6 12.1 0.0 1.1 12.4 0.0 0.8 CHRD ENSG00000090539 Chordin Q9H2X0 3 184380073-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 130.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 31.2;Excitatory neurons: 28.2;Fibroblasts: 16.4;Hepatocytes: 36.4;Inhibitory neurons: 37.5;Skeletal myocytes: 19.1;Smooth muscle cells: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 11.8;MCF7: 2.5;SuSa: 4.0;U-2 OS: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035827 Approved "Secreted in other tissues" NA NA 350000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 36: Stromal cells - Cell proliferation" "HPA035827: AB_10669657" "unprognostic (2.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.63e-2)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (6.55e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (5.53e-3)" "unprognostic (1.85e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-3)" 11.1 12.2 13.9 2.1 13.9 0.0 9.9 19.0 21.2 40.0 9.1 7.6 1.6 32.9 3.2 3.3 15.0 2.5 11.2 15.1 9.4 18.8 130.0 7.2 1.5 10.1 9.9 16.3 17.1 1.1 6.0 2.4 10.2 9.7 0.8 0.0 3.8 5.2 4.4 5.4 6.0 4.6 10.3 9.7 7.8 1.1 9.7 0.2 7.7 2.7 0.3 7.2 15.4 13.6 0.0 0.0 0.3 1.1 0.1 0.1 1.4 0.3 0.0 0.2 0.1 2.8 0.0 0.0 1.1 0.3 1.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 11.8 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 4.0 1.4 0.0 0.0 0.0 3.8 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 13.9 19.0 21.2 15.1 9.4 10.1 9.9 10.2 10.3 9.7 13.6 2.6 0.0 0.0 11.8 0.4 2.7 0.0 0.0 0.6 2.9 2.1 1.8 3.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 3.6 31.2 2.6 0.0 0.0 28.2 3.1 0.0 16.4 1.1 4.5 0.0 0.9 3.3 36.4 0.7 0.0 37.5 0.2 0.0 3.2 3.1 0.0 3.7 0.4 1.8 4.7 0.0 0.0 0.0 7.1 2.5 1.1 0.0 2.2 0.0 0.1 0.0 4.0 0.0 0.5 6.6 19.1 16.4 0.3 0.3 0.3 1.1 0.1 0.7 0.1 0.0 0.3 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CHRDL2 BNF1 ENSG00000054938 "Chordin like 2" Q6WN34 11 74696429-74731426 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 145.1;gallbladder: 106.0;lymphoid tissue: 115.8;smooth muscle: 122.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 194.1;Hepatocytes: 112.2;Skeletal myocytes: 533.4" "Cancer enhanced" "Detected in many" "stomach cancer: 14.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;PC-3: 1.3;SiHa: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021771, HPA076522" Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 9700000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA021771: AB_1846689, HPA076522: " "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (7.24e-2)" "unprognostic (3.41e-3)" "unprognostic (9.45e-2)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (4.33e-2)" "unprognostic (6.64e-2)" "unprognostic (2.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (7.58e-6)" "unprognostic (8.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (6.08e-4)" 2.7 0.2 0.6 115.8 0.4 0.0 5.1 0.4 0.7 64.7 0.1 88.7 4.1 145.1 0.8 4.1 9.4 106.0 24.4 0.4 0.6 5.2 46.3 2.9 0.4 1.0 0.6 2.5 3.1 0.4 0.4 4.5 0.7 22.6 2.6 0.5 0.5 8.9 6.6 1.2 10.8 122.1 2.3 1.3 57.7 3.4 0.7 0.0 0.9 4.8 2.8 46.3 21.2 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.4 0.3 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.4 0.7 0.4 0.6 1.0 0.6 0.7 2.3 0.7 0.2 1.2 0.0 2.6 0.7 0.3 0.3 0.5 0.2 0.0 0.0 194.1 3.8 2.2 15.7 0.1 9.2 0.0 0.0 0.8 0.0 0.0 13.8 31.4 0.6 0.2 2.1 0.0 0.0 0.1 10.3 0.1 5.3 0.0 0.5 0.0 0.2 2.9 112.2 0.1 0.0 0.2 0.0 0.0 2.4 0.0 2.4 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.5 0.1 4.1 0.0 0.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 533.4 1.2 0.6 4.3 0.0 0.0 0.1 0.5 0.4 0.0 0.5 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 27.5 18.6 10.3 18.5 9.8 23.0 21.7 9.0 11.8 19.5 14.4 7.7 6.0 17.3 9.5 10.8 14.9 22.7 20.1 9.2 10.3 13.7 10.0 23.6 11.6 14.2 13.8 19.7 7.3 7.4 8.5 46.7 11.9 14.4 8.2 7.0 10.1 11.4 6.5 15.0 7.7 20.0 11.5 13.9 10.4 8.7 12.5 10.5 10.0 7.4 10.3 34.8 14.0 9.8 9.1 11.2 36.8 18.7 18.9 25.0 24.5 21.8 19.2 25.8 26.2 9.7 7.1 22.0 12.7 36.3 16.8 24.7 24.5 27.7 28.2 24.6 12.4 43.4 12.2 11.4 23.3 66.9 42.9 23.2 22.8 22.3 20.1 29.3 30.8 9.7 16.2 216.3 19.7 7.9 9.2 46.3 42.5 17.7 7.9 20.6 36.9 32.8 18.1 17.7 6.4 34.6 23.0 11.1 40.8 29.8 12.6 81.6 26.2 41.9 24.1 20.0 46.5 38.2 94.5 12.7 32.5 62.2 32.0 0.0 1.3 2.9 1.5 0.8 1.7 0.9 0.9 1.6 0.8 1.0 0.5 1.0 4.9 0.7 0.9 0.5 1.8 0.6 10.3 9.8 9.0 11.8 9.2 10.3 14.2 13.8 11.9 11.5 12.5 9.8 55.0 0.0 15.7 27.7 11.4 57.9 20.7 10.1 20.5 10.7 41.9 29.8 9.3 5.7 9.4 16.5 6.2 6.1 14.6 1.6 1.9 5.3 1.2 10.0 33.4 45.8 3.0 12.0 34.2 2.2 28.8 40.0 5.1 13.8 25.9 51.9 60.0 5.4 16.6 38.7 36.1 3.6 10.2 17.8 37.1 2.5 55.0 41.2 26.6 59.0 10.2 9.2 10.3 21.1 24.2 5.5 2.5 47.0 9.3 19.3 1.2 2.4 8.1 7.5 46.0 47.9 53.5 3.9 7.5 10.5 62.5 13.8 15.2 23.0 3.9 10.2 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CILP2 MGC45771 ENSG00000160161 "Cartilage intermediate layer protein 2" Q8IUL8 19 19538248-19546659 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.5" "Cell type enhanced" "Detected in some" "Early spermatids: 26.2;Late spermatids: 21.8;Sertoli cells: 6.6;Spermatocytes: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.6;HEK 293: 2.8;NB-4: 2.2;THP-1: 2.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "medulla oblongata: 2.7;spinal cord: 7.3" HPA041847 Uncertain "Secreted to extracellular matrix" NA NA 22000000 "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041847: AB_10795599" "unprognostic (6.51e-2)" "unprognostic (2.54e-2)" "unprognostic (5.42e-4)" "prognostic unfavorable (3.22e-6)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (4.31e-2)" "unprognostic (4.13e-3)" "unprognostic (4.48e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (5.09e-2)" "unprognostic (1.41e-2)" "unprognostic (0.00e+0)" "unprognostic (1.59e-2)" "unprognostic (3.19e-2)" "unprognostic (3.12e-3)" "unprognostic (1.36e-2)" 0.8 0.0 0.4 0.2 0.7 1.0 0.3 0.0 0.4 0.3 0.0 0.1 0.0 0.2 0.1 0.0 0.4 1.5 0.4 0.4 1.2 0.3 0.2 0.4 0.3 0.2 0.2 1.6 0.0 0.1 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.1 0.0 0.2 0.0 5.5 0.9 0.0 1.0 0.0 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 4.6 0.1 0.6 0.6 0.0 0.3 0.0 1.3 0.5 0.0 1.2 0.2 0.0 0.5 0.1 0.0 0.0 0.3 2.8 0.0 0.1 0.1 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.2 1.7 1.5 0.9 0.3 0.0 0.0 0.0 0.0 0.1 1.2 0.3 1.5 0.1 0.2 0.3 2.8 0.0 0.0 0.5 0.2 0.1 0.4 1.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.4 0.4 1.2 0.2 0.2 0.2 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 0.5 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 26.2 0.3 0.3 0.1 0.0 0.0 0.2 0.0 0.2 1.5 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.3 21.8 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.4 0.0 0.1 0.0 0.0 6.6 0.4 0.3 27.8 4.0 0.7 0.6 0.0 0.2 0.1 0.0 0.5 CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 345.1;Spermatocytes: 300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1384.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA062779 Approved Vesicles "Secreted to blood" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062779: AB_2684867" "unprognostic (1.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (3.06e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.79e-2)" "unprognostic (8.05e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.06e-9)" "unprognostic (2.36e-1)" "unprognostic (2.65e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.07e-1)" 36.5 31.1 26.3 54.8 26.2 68.2 36.0 27.4 29.8 27.7 25.9 42.1 31.8 23.8 27.4 19.2 31.1 40.3 16.5 25.7 28.8 21.0 29.6 36.2 61.5 28.1 27.6 25.6 17.9 58.0 19.7 29.7 28.9 15.5 42.5 9.7 19.7 18.4 14.8 16.9 38.7 33.5 27.9 67.0 25.6 56.8 26.4 90.0 23.7 20.1 51.2 46.1 20.0 29.6 194.6 169.2 34.7 101.5 92.7 76.1 25.5 95.2 72.4 101.7 150.9 158.8 231.4 75.8 116.6 81.8 106.4 102.5 70.5 57.2 142.1 94.2 35.3 55.5 145.0 197.3 56.0 175.7 144.1 52.0 45.3 126.9 44.9 122.1 122.8 229.4 90.8 212.8 129.2 64.8 169.9 172.1 11.5 114.0 273.1 287.5 184.2 215.6 343.2 106.3 48.8 58.8 290.5 19.3 93.0 23.3 55.5 116.5 76.6 146.5 131.8 51.0 113.5 100.3 224.0 393.0 123.5 151.5 121.1 807.1 380.9 773.3 187.6 203.9 238.9 100.6 174.8 186.6 317.6 97.7 92.7 126.4 1384.5 187.6 199.2 161.6 236.0 401.2 26.3 26.2 27.4 29.8 25.7 28.8 28.1 27.6 28.9 27.9 26.4 29.6 65.7 19.2 49.0 0.0 68.7 27.3 24.7 84.2 12.0 8.4 80.8 94.0 1.8 87.2 50.8 57.0 0.0 54.8 109.7 57.1 17.6 141.4 67.7 34.8 21.5 52.4 33.0 63.5 0.0 130.0 117.7 38.6 21.4 17.5 345.1 17.7 67.5 38.4 247.4 1.7 0.0 73.6 61.1 138.2 238.4 31.4 49.4 244.2 40.9 0.0 157.8 28.1 188.4 0.0 0.0 224.2 51.3 30.1 94.6 10.0 95.9 83.4 79.3 9.0 32.9 24.5 38.1 300.0 77.1 30.8 23.0 17.4 192.6 23.9 79.0 25.8 CLCA1 "CaCC, CLCRG1" ENSG00000016490 "Chloride channel accessory 1" A8K7I4 1 86468368-86500259 "Predicted secreted proteins, Transporters" "Calcium transport, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 1399.9" "Cell type enriched" "Detected in some" 16 "Intestinal goblet cells: 3524.6" "Group enriched" "Detected in some" 9 "colorectal cancer: 86.8;pancreatic cancer: 27.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;NB-4: 2.5;RPMI-8226: 2.9;SH-SY5Y: 1.8;U-2197: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052787, HPA059301" Enhanced "Secreted to digestive system" NA NA 77000 "Cluster 9: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA052787: AB_2681947, HPA059301: AB_2683971" "prognostic favorable (2.98e-4)" "unprognostic (3.42e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-1)" 1.1 0.0 0.0 109.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 739.9 909.7 1.2 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 1061.8 0.0 0.0 0.5 0.0 0.0 1399.9 15.4 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 0.0 0.1 0.0 0.0 0.0 6.7 0.0 0.3 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 3524.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 54.8 0.0 0.0 0.0 213.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 68.3 0.1 CLCF1 "BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6" ENSG00000175505 "Cardiotrophin like cytokine factor 1" Q9UBD9 11 67364168-67374177 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 41.8;Glandular and luminal cells: 104.9;Pancreatic endocrine cells: 56.2;Prostatic glandular cells: 56.4;Urothelial cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042444 Uncertain Approved "Nuclear bodies,Vesicles" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Vesicles" "HPA042444: AB_10794527" "unprognostic (2.68e-1)" "unprognostic (7.87e-3)" "unprognostic (6.21e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (9.91e-4)" "unprognostic (1.61e-2)" "unprognostic (1.09e-3)" "unprognostic (1.47e-2)" "unprognostic (5.08e-2)" "unprognostic (2.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.54e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.17e-2)" "unprognostic (2.37e-1)" 16.2 6.0 1.3 8.0 0.5 13.7 5.3 0.0 1.5 13.9 0.9 13.4 1.4 16.6 1.0 4.4 17.1 17.7 8.8 1.0 0.6 19.0 4.2 9.3 5.3 1.4 0.5 6.7 6.5 0.2 6.5 4.2 0.4 7.2 1.7 1.4 9.1 1.8 1.5 2.6 9.4 8.3 0.0 8.1 11.2 1.9 2.1 0.7 9.7 1.9 4.4 18.1 7.6 0.2 15.1 31.4 2.2 9.7 4.2 5.8 0.0 20.9 11.6 14.4 7.0 5.1 40.3 9.1 17.1 26.8 17.5 10.3 0.4 10.7 6.3 0.5 0.3 0.1 23.9 4.0 13.6 1.9 2.4 7.6 2.6 15.0 6.5 27.4 3.1 0.0 3.5 0.4 15.0 12.0 0.1 6.8 8.1 18.9 28.8 0.9 4.8 0.5 22.7 0.8 0.1 1.6 57.8 2.2 1.3 4.4 1.3 2.5 12.5 27.6 11.6 35.4 31.5 2.0 0.1 1.0 35.4 1.8 11.1 0.0 0.9 15.2 10.5 3.4 6.2 10.8 4.8 8.3 1.3 13.8 0.1 3.5 0.3 0.2 10.5 0.0 1.1 3.2 1.3 0.5 0.0 1.5 1.0 0.6 1.4 0.5 0.4 0.0 2.1 0.2 4.2 16.0 4.8 1.3 10.6 3.7 25.9 6.5 1.8 0.0 14.5 2.4 0.8 25.8 9.6 7.3 0.0 0.4 10.0 3.8 1.9 24.0 1.8 41.8 19.4 6.2 1.2 0.0 0.7 11.8 0.6 14.0 5.1 104.9 3.8 2.1 2.9 1.0 1.2 0.0 0.5 2.3 6.1 0.3 10.7 4.7 3.4 6.7 8.8 1.0 6.5 1.7 3.1 0.5 0.1 56.2 14.3 0.0 9.5 56.4 0.2 5.2 1.7 0.3 0.0 32.6 10.4 0.3 0.9 1.6 4.4 0.1 9.7 0.1 1.5 65.2 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC18A MRCL ENSG00000157322 "C-type lectin domain family 18 member A" A5D8T8 16 69950705-69964452 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 23.9" "Cell type enriched" "Detected in some" 23 "Proximal tubular cells: 78.0" "Cancer enriched" "Detected in single" 7 "renal cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (1.68e-1)" "unprognostic (3.06e-2)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (3.14e-2)" "unprognostic (4.62e-2)" "unprognostic (1.36e-1)" "unprognostic (4.14e-2)" "unprognostic (1.04e-1)" "unprognostic (4.40e-2)" "unprognostic (6.77e-4)" "unprognostic (6.73e-2)" "unprognostic (4.58e-2)" "unprognostic (2.06e-1)" "unprognostic (9.03e-4)" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" 0.2 0.9 0.1 0.0 0.2 0.3 0.3 0.6 0.5 0.3 2.8 0.4 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.2 0.2 23.9 0.2 0.4 0.1 0.2 0.2 0.2 0.4 0.1 0.4 0.0 0.4 0.3 0.1 0.1 0.6 0.0 0.2 0.3 0.7 0.0 0.2 1.2 0.5 3.2 0.2 0.3 0.4 0.1 0.1 0.3 0.1 0.3 0.0 0.1 0.7 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.5 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.3 0.3 0.0 1.1 0.0 0.9 0.1 0.0 0.2 0.0 1.6 0.3 0.4 0.5 2.8 0.4 0.0 2.1 0.1 0.3 3.3 1.9 0.3 0.4 0.4 0.1 0.4 0.0 0.0 0.3 0.2 0.1 0.3 2.0 0.5 0.0 0.6 2.5 0.4 0.4 3.3 0.4 1.0 0.0 0.6 0.3 0.8 0.3 1.1 0.0 0.0 0.9 0.9 1.0 0.0 0.0 0.5 0.4 0.0 0.2 0.2 1.5 78.0 0.7 1.3 0.0 0.7 1.3 0.5 0.2 0.0 0.0 0.3 0.6 0.6 1.3 0.2 CLEC18B MRCL2 ENSG00000140839 "C-type lectin domain family 18 member B" Q6UXF7 16 74408270-74421953 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 33.4;testis: 11.8" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 26.8" "Cancer enhanced" "Detected in some" "glioma: 2.7;renal cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.1;JURKAT: 1.6;K-562: 3.1;U-266/70: 1.1" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (5.69e-2)" "unprognostic (1.46e-1)" "unprognostic (5.30e-3)" "unprognostic (9.37e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (7.15e-2)" "unprognostic (7.51e-2)" "unprognostic (4.49e-3)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" "unprognostic (9.91e-2)" "unprognostic (3.58e-2)" "unprognostic (1.42e-2)" "unprognostic (2.31e-2)" "unprognostic (5.87e-2)" "unprognostic (5.43e-2)" "unprognostic (4.27e-2)" 0.1 1.9 3.4 0.4 3.7 0.1 0.2 4.5 4.9 0.5 2.6 0.2 0.4 0.1 0.6 2.7 0.3 0.3 0.2 3.8 3.8 33.4 0.6 0.2 0.1 3.7 3.6 0.2 0.6 0.0 0.8 0.1 4.0 0.5 0.1 2.3 0.6 0.0 0.2 0.2 0.3 0.1 3.6 0.6 0.3 11.8 3.3 0.2 0.6 0.0 0.0 0.1 1.7 4.4 0.0 0.6 1.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.6 0.1 0.0 0.0 0.2 0.0 1.6 3.1 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.3 0.1 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.3 1.1 0.7 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.7 4.5 4.9 3.8 3.8 3.7 3.6 4.0 3.6 3.3 4.4 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 1.9 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.5 0.1 0.0 0.0 0.0 0.4 26.8 0.0 1.4 0.0 0.0 0.2 0.5 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 CLEC18C "MGC34761, MRCL3" ENSG00000157335 "C-type lectin domain family 18 member C" Q8NCF0 16 70173322-70187361 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 17.8" "Cell type enriched" "Detected in single" 46 "Proximal tubular cells: 23.3" "Cancer enriched" "Detected in single" 9 "renal cancer: 1.4" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048976 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA048976: AB_2680582" "unprognostic (3.90e-1)" "unprognostic (3.03e-1)" "unprognostic (1.20e-4)" "unprognostic (5.55e-2)" "unprognostic (5.72e-3)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (6.98e-2)" 0.0 0.1 0.1 0.0 0.3 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 17.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.5 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CLEC19A ENSG00000261210 "C-type lectin domain containing 19A" Q6UXS0 16 19285731-19322145 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.7" "Group enriched" "Detected in some" 4 "Microglial cells: 6.5;Respiratory ciliated cells: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.19e-1)" "unprognostic (3.72e-1)" "unprognostic (1.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" 0.0 0.0 2.5 0.0 1.8 0.0 0.0 1.2 2.7 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.8 1.2 2.7 2.2 0.2 0.0 0.7 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 CLEC3A CLECSF1 ENSG00000166509 "C-type lectin domain family 3 member A" O75596 16 78022515-78066761 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;breast: 9.3;urinary bladder: 5.8" "Cell type enriched" "Detected in single" 7 "Prostatic glandular cells: 4.7" "Cancer enriched" "Detected in some" 102 "breast cancer: 78.5" "Region enriched" "Detected in single" 6 "midbrain: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SK-BR-3: 7.4;T-47d: 21.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA051511 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "HPA051511: AB_2681514" "prognostic unfavorable (1.61e-4)" "unprognostic (1.60e-1)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "unprognostic (3.80e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.2 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 5.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 4.2 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 420.3" "Cell type enhanced" "Detected in some" "Adipocytes: 76.3;Endothelial cells: 27.9;Fibroblasts: 126.4;Hepatic stellate cells: 57.5;Leydig cells: 30.1;Microglial cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 297.9;ASC TERT1: 591.9;U-2197: 120.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" NA NA 6540000000 25000000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" 420.3 51.0 44.4 9.3 46.4 1.7 214.8 45.5 66.6 89.4 50.9 83.9 31.6 60.4 17.1 49.9 41.1 35.6 259.9 43.0 42.9 131.4 29.0 201.2 33.1 51.3 56.1 26.0 14.6 14.3 27.7 142.8 48.0 33.5 37.4 0.7 49.8 19.1 74.8 149.7 78.2 25.5 44.8 264.5 43.5 113.2 50.7 10.1 88.4 68.0 8.2 100.9 74.9 43.0 0.0 0.0 0.1 0.2 297.9 591.9 0.0 40.1 62.9 1.2 6.2 0.0 0.0 0.1 0.1 3.1 0.0 0.1 0.0 0.1 0.1 0.3 0.9 0.6 0.1 0.1 0.5 0.1 0.7 47.5 0.1 0.3 0.1 0.4 0.5 0.3 0.0 1.7 0.5 0.2 0.0 2.2 0.0 0.0 0.6 0.0 0.1 2.2 0.0 0.0 0.3 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 4.5 0.2 120.6 0.1 1.0 1.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.4 46.4 45.5 66.6 43.0 42.9 51.3 56.1 48.0 44.8 50.7 43.0 76.3 0.0 0.0 1.6 0.3 3.4 0.0 0.0 1.8 0.0 0.7 0.3 0.8 1.5 0.0 0.0 0.0 0.0 0.5 0.0 3.9 0.0 4.0 0.3 16.9 27.9 0.0 2.7 0.8 0.2 0.0 126.4 3.1 0.3 0.0 0.0 57.5 0.3 0.9 0.0 0.6 0.0 0.0 1.2 9.5 19.5 30.1 2.2 3.6 69.3 0.7 0.4 0.0 1.5 0.7 0.1 0.0 6.4 0.5 0.0 0.0 0.0 0.0 0.3 0.0 1.0 12.3 0.0 0.0 0.7 3.8 0.1 0.7 0.4 0.0 0.0 CLPS ENSG00000137392 Colipase P04118 6 35794982-35797344 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Digestion, Lipid degradation, Lipid metabolism" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1696 "pancreas: 262086.0" "Cell type enriched" "Detected in some" 17 "Exocrine glandular cells: 23175.0" "Cancer enriched" "Detected in many" 188 "pancreatic cancer: 1726.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA010512 Enhanced "Secreted to digestive system" NA NA 1600000 "Cluster 15: NK-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA010512: AB_1846979" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.12e-3)" "unprognostic (2.47e-1)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" 30.4 6.1 0.9 5.8 1.8 9.0 17.8 0.1 0.7 13.4 0.2 6.8 40.2 6.0 5.6 9.9 3.8 0.0 46.3 1.2 0.1 5.5 17.7 4.1 10.5 0.2 0.2 154.4 262086.0 0.0 6.3 11.9 0.3 7.9 0.0 0.0 41.7 0.0 5.8 8.1 24.0 0.0 0.1 7.9 27.7 4.0 0.6 0.0 3.8 0.0 0.0 3.3 5.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.6 0.3 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.9 1.8 0.1 0.7 1.2 0.1 0.2 0.2 0.3 0.1 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.6 0.0 0.0 0.0 1.1 11.9 0.0 0.0 23175.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 130.8 0.0 0.0 0.0 0.0 1331.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLPSL1 "C6orf127, dJ510O8.6" ENSG00000204140 "Colipase like 1" A2RUU4 6 35781019-35793675 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 90 "epididymis: 607.6;pancreas: 178.4" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 39.0" "Group enriched" "Detected in some" 6 "breast cancer: 3.6;cervical cancer: 1.0;endometrial cancer: 2.8;ovarian cancer: 1.8;pancreatic cancer: 3.4" "Group enriched" "Detected in many" 4 "amygdala: 1.1;basal ganglia: 2.5;cerebral cortex: 2.3;hippocampal formation: 2.9;white matter: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "T-47d: 8.4" HPA073155 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA073155: AB_2686576" "unprognostic (7.97e-2)" "unprognostic (1.58e-1)" "unprognostic (4.75e-1)" "unprognostic (2.54e-1)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.60e-2)" "unprognostic (7.06e-3)" 0.1 0.3 1.1 0.0 2.5 0.0 4.3 0.3 2.3 0.0 0.2 0.0 0.0 0.0 607.6 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.3 0.4 0.1 178.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.5 2.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 8.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.5 0.3 2.3 2.9 0.3 0.3 0.4 0.3 0.3 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 39.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CLPSL2 "C6orf126, dJ510O8.5, UNQ3045" ENSG00000196748 "Colipase like 2" Q6UWE3 6 35776594-35779552 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 532.1" "Group enriched" "Detected in some" 4 "Breast glandular cells: 3.4;Breast myoepithelial cells: 2.2;Enteroendocrine cells: 1.8;Exocrine glandular cells: 4.0;Pancreatic endocrine cells: 2.1;Spermatogonia: 2.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "T-47d: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA051655 Approved "Secreted in male reproductive system" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA051655: " "unprognostic (2.38e-1)" "unprognostic (3.65e-1)" "unprognostic (6.39e-3)" "unprognostic (9.38e-2)" "unprognostic (4.03e-2)" "unprognostic (2.47e-1)" "unprognostic (4.85e-3)" "unprognostic (8.69e-2)" "unprognostic (3.17e-2)" "unprognostic (3.95e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.2 0.8 0.0 0.2 0.0 0.0 0.0 532.1 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.0 5.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.7 0.7 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.7 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.3 0.0 0.1 6.3 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.4 0.2 0.8 0.6 0.4 0.2 0.4 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 2.2 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.2 4.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Group enriched" "Detected in all" 4 "Cholangiocytes: 2586.5;Collecting duct cells: 3525.7;Hepatocytes: 4230.2;Muller glia cells: 8522.6" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cell line enhanced" "Detected in all" "HeLa: 3644.3;SK-BR-3: 3500.4;T-47d: 2562.4;U-2 OS: 2225.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" 1438.7 3809.7 6730.2 897.0 6536.5 53.2 1423.8 6992.3 8050.5 1389.4 6057.7 1407.9 323.9 1152.5 9148.8 768.6 3543.7 2863.5 617.7 6660.5 8149.9 1170.5 9779.1 827.8 2309.4 10230.8 8450.9 756.7 2246.3 1689.2 827.2 131.2 8001.8 986.4 276.1 3274.6 1453.0 5466.4 114.1 281.9 662.7 1439.9 8813.6 295.4 1081.6 2709.4 7385.0 388.1 2406.8 267.7 2343.1 1777.4 741.0 9752.3 13.0 1673.1 73.2 86.4 401.4 546.1 230.7 297.8 584.8 77.3 40.1 323.4 265.5 6.6 1159.9 267.1 926.6 561.2 318.4 48.1 50.3 1268.7 306.4 741.8 3644.3 403.7 348.8 19.2 1891.2 923.4 189.1 334.0 95.5 719.5 1028.1 10.6 10.1 842.2 27.5 288.4 5.7 56.5 603.3 505.3 197.6 6.5 276.1 236.3 763.0 1220.2 66.7 41.7 412.3 3500.4 18.1 349.1 2562.4 10.3 153.2 24.0 2225.3 131.8 101.9 108.1 419.0 16.1 1808.8 122.4 10.3 767.1 18.4 8.9 19.8 6.2 7.4 0.7 23.1 21.3 6.2 1.6 2.8 7.0 79.8 9.3 1.1 11.8 6.5 1073.6 6730.2 6536.5 6992.3 8050.5 6660.5 8149.9 10230.8 8450.9 8001.8 8813.6 7385.0 9752.3 255.3 32.1 91.8 720.5 16.1 81.3 944.6 134.1 118.9 74.3 475.3 480.4 86.1 2586.5 514.0 3525.7 77.2 116.3 15.2 23.6 41.1 488.3 311.3 196.9 31.1 442.0 9.5 92.4 73.4 620.7 22.7 614.8 226.8 185.6 803.0 31.4 1037.7 4230.2 12.6 30.3 81.0 30.9 28.5 180.5 88.9 789.3 114.3 244.6 206.3 69.3 25.1 8522.6 11.3 61.3 54.3 174.8 15.0 57.2 11.6 200.5 9.9 459.2 709.1 221.4 13.1 334.4 157.7 189.8 20.3 58.8 55.3 85.6 58.7 288.9 49.3 353.7 CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "retina: 297.9" "Cell type enriched" "Detected in many" 7 "Rod photoreceptor cells: 407.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 34.3" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" NA NA 11000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: AB_2732286" "unprognostic (1.75e-2)" "unprognostic (9.15e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (7.81e-3)" "unprognostic (3.00e-3)" "unprognostic (1.96e-1)" "unprognostic (2.97e-3)" "unprognostic (8.38e-3)" "unprognostic (3.76e-2)" "unprognostic (4.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.36e-4)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" 0.4 1.0 2.7 0.5 6.1 3.9 2.3 2.0 4.0 1.5 7.2 0.9 0.5 1.4 0.5 1.2 1.8 2.0 0.3 3.1 4.2 5.3 0.5 1.4 0.7 3.0 3.4 4.9 1.3 3.6 3.9 0.6 3.1 8.5 0.1 297.9 2.3 1.1 0.2 0.7 1.4 0.1 3.1 0.1 3.1 2.6 4.3 1.7 6.8 0.0 0.0 0.8 0.1 9.5 3.6 5.4 10.1 6.8 0.0 0.0 6.1 3.9 0.3 0.0 0.0 4.2 2.1 4.3 1.0 0.0 3.6 1.5 0.0 0.6 0.0 3.6 9.3 7.3 2.9 34.3 0.0 2.5 1.3 0.3 0.0 0.0 0.0 1.7 0.4 10.5 10.5 12.3 0.0 1.2 4.4 7.8 0.7 4.4 2.4 8.8 4.8 15.5 1.1 1.1 8.8 6.2 4.0 2.5 3.4 8.0 3.3 1.0 0.8 4.0 5.7 2.8 2.0 6.9 13.3 9.7 3.2 4.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 2.7 6.1 2.0 4.0 3.1 4.2 3.0 3.4 3.1 3.1 4.3 9.5 0.1 0.0 2.6 0.3 0.1 0.0 3.8 1.5 2.8 29.6 2.8 5.0 0.2 0.0 1.7 0.0 20.9 0.8 0.0 0.1 1.9 0.4 0.7 2.5 0.3 2.0 0.0 0.0 5.2 0.2 0.1 0.4 0.0 3.2 0.0 3.5 0.0 0.0 0.2 16.8 3.8 0.0 0.0 0.0 0.3 0.8 0.9 0.2 0.0 1.0 0.0 58.1 0.0 0.0 4.9 0.0 0.0 1.2 0.0 5.5 0.0 0.5 2.4 407.5 6.6 0.0 0.3 10.6 8.6 0.2 0.1 0.4 0.1 17.3 0.1 1.6 CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 18.5" "Cell type enriched" "Detected in some" 28 "granulocytes: 53.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000363, HPA052634" Enhanced Supported "Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 3000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 60: Granulocytes - Receptor signaling" "Cytoplasmic bodies" Cytosol "CAB000363: AB_2083616, HPA052634: AB_2681892" "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" 9.0 0.0 0.2 3.7 0.1 0.2 18.5 0.0 0.2 4.6 0.3 8.7 0.6 3.1 4.3 10.2 0.9 7.3 1.6 0.1 0.2 0.2 0.5 1.5 1.8 0.5 0.3 0.1 1.6 0.6 0.2 0.1 0.3 1.0 8.3 0.0 4.7 1.3 0.9 9.0 5.8 2.2 0.3 0.2 1.5 0.9 0.2 3.0 0.4 3.0 2.4 11.1 0.9 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.2 0.1 0.2 0.5 0.3 0.3 0.3 0.2 0.2 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 53.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 CNBD1 FLJ35802 ENSG00000176571 "Cyclic nucleotide binding domain containing 1" Q8NA66 8 86866415-87615219 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 6.6" "Group enriched" "Detected in some" 33 "Early spermatids: 155.4;Late spermatids: 92.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 4.4;U-266/70: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025037, HPA027469, HPA027786" Uncertain "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA025037: AB_10794318, HPA027469: AB_10599492, HPA027786: AB_10600231" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 155.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 92.3 1.2 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534500-74587212 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 85.6" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 361.7" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 38 "U-266/84: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008933, HPA073283" Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 70: Brain - Nervous system development" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008933: AB_1847033, HPA073283: " "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 0.0 0.0 27.4 0.0 74.2 0.1 0.0 80.4 39.0 0.0 6.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 30.5 51.3 0.5 12.9 0.0 0.0 85.6 76.9 0.0 0.0 0.0 0.2 0.0 74.3 0.1 0.0 0.1 0.0 0.1 1.4 0.1 0.2 0.0 39.7 0.0 0.0 0.3 74.9 0.0 0.2 0.0 0.0 0.0 0.0 80.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 15.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 27.4 74.2 80.4 39.0 30.5 51.3 85.6 76.9 74.3 39.7 74.9 80.7 0.2 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.0 0.6 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 8.6 0.5 0.2 0.2 0.0 2.7 1.2 0.2 0.0 0.3 0.0 1.5 0.0 0.2 0.7 35.1 0.1 0.0 1.5 0.7 0.0 1.2 1.1 3.1 0.0 0.2 0.0 1.0 0.0 0.5 0.0 3.0 361.7 0.2 0.1 0.0 0.0 0.4 0.4 24.5 0.0 1.0 0.0 0.6 0.2 1.0 0.4 0.0 0.3 0.0 0.4 0.0 0.5 0.2 CNMD "BRICD3, CHM-I, CHM1, LECT1, MYETS1" ENSG00000136110 Chondromodulin O75829 13 52703264-52739820 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;retina: 8.4;salivary gland: 6.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "glioma: 1.5;lung cancer: 6.0;testis cancer: 5.8;thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 35 "NTERA-2: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010510 Uncertain "Secreted to extracellular matrix" NA NA 9500 "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" "HPA010510: AB_10602021" "unprognostic (7.52e-3)" "unprognostic (1.34e-1)" "unprognostic (7.36e-2)" "unprognostic (1.45e-2)" "unprognostic (1.15e-1)" "unprognostic (3.22e-1)" "unprognostic (2.84e-2)" "unprognostic (2.63e-2)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-1)" 0.0 0.0 1.8 0.0 4.9 0.0 0.0 2.3 2.6 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 2.0 0.0 0.0 1.6 0.0 2.4 2.3 0.0 0.3 0.0 1.0 0.1 2.2 0.5 0.0 8.4 6.7 0.0 0.1 0.0 0.1 0.0 2.7 0.3 0.0 1.8 2.4 0.1 3.3 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 4.9 2.3 2.6 1.8 2.0 2.4 2.3 2.2 2.7 2.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CNTN2 "AXT, TAG-1, TAX, TAX1" ENSG00000184144 "Contactin 2" Q02246 1 205042937-205078289 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 248.9" "Cell type enriched" "Detected in some" 11 "Oligodendrocytes: 335.5" "Cancer enriched" "Detected in some" 9 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 3.9;SCLC-21H: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001397, HPA012497" Approved "Secreted in brain" NA NA 58000 "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA001397: AB_1847146, HPA012497: AB_1847147" "unprognostic (1.90e-1)" "unprognostic (1.86e-1)" "unprognostic (2.87e-2)" "unprognostic (4.52e-3)" "unprognostic (2.98e-2)" "unprognostic (5.96e-2)" "unprognostic (3.25e-1)" "unprognostic (1.43e-2)" "unprognostic (8.56e-2)" "unprognostic (2.40e-1)" "unprognostic (3.44e-3)" "unprognostic (5.62e-2)" "unprognostic (1.73e-7)" "unprognostic (9.82e-3)" "unprognostic (1.19e-1)" "unprognostic (3.35e-2)" "unprognostic (3.07e-2)" 0.3 0.5 82.6 0.4 145.4 0.0 0.1 125.7 112.4 0.6 32.4 2.1 0.1 0.0 0.0 0.2 0.1 0.1 0.7 85.2 96.6 0.1 0.0 0.0 0.0 161.6 128.1 0.0 0.1 0.0 8.0 0.0 139.8 0.3 0.5 1.2 0.4 0.6 0.0 0.5 0.9 0.2 110.1 0.1 0.5 6.1 125.7 0.1 0.1 0.0 0.3 0.2 0.7 248.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 82.6 145.4 125.7 112.4 85.2 96.6 161.6 128.1 139.8 110.1 125.7 248.9 0.4 0.0 0.6 1.3 0.1 0.0 0.0 0.0 0.0 2.4 0.9 1.3 3.7 0.0 0.6 1.8 0.0 0.0 1.2 0.0 0.0 0.6 13.7 0.6 0.5 0.5 0.0 0.0 18.4 0.6 0.0 0.4 0.0 1.2 0.0 2.6 0.0 0.0 0.0 3.3 16.0 0.0 0.0 0.0 0.0 29.0 0.6 0.5 0.0 4.7 0.0 0.2 0.0 9.5 335.5 0.6 0.0 0.0 0.4 0.0 0.0 0.3 1.5 0.8 0.0 0.0 0.3 3.2 0.6 0.0 0.0 0.0 0.5 0.2 0.0 0.2 COCH "COCH-5B2, DFNA31, DFNA9" ENSG00000100473 Cochlin O43405 14 30874514-30895065 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "pancreas: 502.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 63.0;Horizontal cells: 84.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 71.3" "Group enriched" "Detected in some" 12 "memory B-cell: 38.3;naive B-cell: 17.7" "Lineage enriched" "Detected in many" 17 "B-cells: 38.3" "Cell line enhanced" "Detected in many" "HEK 293: 95.7;Hep G2: 63.8;K-562: 129.1;NB-4: 105.5;SCLC-21H: 111.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 50.8" HPA065086 Supported Vesicles "Secreted in other tissues" NA NA 160000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA065086: " "unprognostic (8.36e-3)" "unprognostic (2.51e-2)" "unprognostic (8.61e-2)" "unprognostic (1.64e-2)" "unprognostic (6.48e-2)" "unprognostic (6.53e-2)" "unprognostic (9.61e-2)" "unprognostic (4.03e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.27e-2)" "unprognostic (2.91e-3)" "unprognostic (5.42e-3)" "unprognostic (3.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.72e-1)" 3.2 3.7 7.3 2.8 71.3 4.0 3.4 1.4 20.9 17.4 19.0 3.2 0.8 0.6 2.2 0.9 6.2 2.9 1.9 5.6 8.0 5.2 0.5 0.6 11.0 2.9 7.9 0.8 502.0 3.4 10.1 1.9 3.7 48.3 2.2 12.1 3.6 73.4 1.3 15.2 2.6 1.1 6.2 2.6 1.7 5.2 12.5 1.3 1.3 5.0 7.7 2.0 23.0 1.7 0.0 35.3 3.1 0.0 0.6 0.1 21.8 0.2 0.0 6.4 17.1 20.9 1.2 0.4 1.7 0.0 1.3 0.1 22.2 0.0 10.6 0.0 95.7 18.1 7.6 63.8 0.0 1.8 7.3 1.3 0.0 0.6 0.0 0.0 0.3 39.9 129.1 5.1 1.6 0.8 9.2 105.5 11.9 0.1 3.7 26.7 0.0 0.9 1.1 3.4 111.8 30.4 2.6 0.6 0.2 12.1 0.0 48.7 0.9 0.0 0.0 0.3 0.1 5.7 15.8 11.2 0.0 0.0 4.7 0.0 0.6 0.0 0.0 0.0 0.0 38.3 0.3 0.0 0.1 17.7 0.0 0.1 0.2 0.0 0.0 0.0 2.2 1.0 7.3 71.3 1.4 20.9 5.6 8.0 2.9 7.9 3.7 6.2 12.5 1.7 2.0 0.0 0.5 3.6 13.4 19.1 2.3 0.3 0.0 2.7 7.9 1.5 0.8 2.8 0.9 0.0 4.2 6.5 1.3 0.6 1.9 0.5 1.5 2.2 0.8 3.1 17.0 7.4 14.3 63.0 14.3 22.0 1.1 1.0 1.3 1.8 5.0 5.0 3.8 84.1 24.2 0.3 6.1 5.0 25.2 2.0 1.5 2.4 19.6 7.5 2.8 14.5 0.0 6.0 16.5 3.7 4.3 6.0 10.0 3.5 0.2 11.7 0.5 4.0 0.0 2.8 9.0 22.1 20.3 0.1 13.5 6.6 3.3 0.1 0.6 1.7 COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.5;choroid plexus: 39.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 26.6;Inhibitory neurons: 6.3;Microglial cells: 8.4;Oligodendrocytes: 27.9" "Cancer enhanced" "Detected in many" "breast cancer: 42.8;pancreatic cancer: 51.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTEC/SVTERT24-B: 39.7" "Low region specificity" "Detected in many" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA053268: " "unprognostic (3.83e-2)" "unprognostic (6.81e-2)" "unprognostic (7.20e-2)" "unprognostic (7.45e-3)" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (3.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" "unprognostic (4.37e-2)" "unprognostic (7.03e-2)" "unprognostic (1.38e-11)" "unprognostic (2.16e-3)" "unprognostic (7.22e-2)" "unprognostic (3.60e-1)" "unprognostic (2.06e-3)" 0.3 0.0 2.2 0.2 8.6 0.3 0.3 4.6 4.5 1.2 39.9 0.2 0.0 0.3 0.0 0.0 0.0 8.9 0.3 1.3 3.3 0.4 0.2 2.8 0.6 7.7 5.6 3.9 3.3 2.5 0.4 0.1 7.1 1.9 0.1 0.9 2.6 0.8 0.1 0.4 0.1 0.5 4.3 2.5 0.1 0.2 6.3 0.1 0.7 0.0 1.9 0.2 0.1 15.5 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.2 2.9 0.4 6.0 0.1 0.0 0.1 0.0 1.0 0.0 0.7 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.0 39.7 0.0 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 6.3 0.1 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 8.6 4.6 4.5 1.3 3.3 7.7 5.6 7.1 4.3 6.3 15.5 2.6 0.0 0.6 3.9 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.1 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.4 26.6 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.4 0.0 2.2 0.0 2.5 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.2 5.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 20.1;retina: 9.6" "Cell type enhanced" "Detected in some" "Astrocytes: 83.9;Excitatory neurons: 99.5;Oligodendrocyte precursor cells: 557.4;Theca cells: 139.6" "Cancer enhanced" "Detected in many" "breast cancer: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 116.9;BJ: 43.2;BJ hTERT+ SV40 Large T+ RasG12V: 85.3;HBF TERT88: 48.7;HSkMC: 142.5;SuSa: 60.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058335 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 640000 "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Endoplasmic reticulum" "HPA058335: AB_2683682" "unprognostic (2.60e-3)" "unprognostic (6.61e-4)" "unprognostic (9.58e-2)" "unprognostic (5.06e-5)" "unprognostic (2.83e-1)" "unprognostic (2.85e-2)" "unprognostic (6.03e-3)" "unprognostic (2.23e-3)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (1.94e-2)" "unprognostic (3.01e-12)" "unprognostic (1.27e-2)" "unprognostic (3.53e-1)" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" 0.6 0.6 4.3 0.3 3.1 0.0 0.4 1.6 4.6 0.9 2.8 0.4 0.1 0.5 0.1 0.0 0.0 3.1 0.0 2.4 2.5 0.1 0.0 0.3 0.1 2.5 3.7 0.6 0.7 0.2 3.3 20.1 2.2 0.2 0.3 9.6 1.5 0.8 0.1 1.4 0.1 0.3 1.0 0.5 0.1 1.4 2.2 0.0 0.1 0.1 0.0 0.2 0.1 2.1 0.0 0.8 116.9 0.0 4.6 5.9 0.0 43.2 16.1 23.3 85.3 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 142.5 0.0 1.1 0.0 17.7 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 8.1 0.0 0.1 0.0 7.4 0.0 15.2 0.0 0.1 0.0 0.0 0.1 0.0 60.5 0.0 0.1 0.0 0.6 27.0 0.0 4.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.1 1.6 4.6 2.4 2.5 2.5 3.7 2.2 1.0 2.2 2.1 0.0 0.0 2.2 83.9 0.0 1.8 0.0 0.0 0.0 9.4 0.1 4.2 0.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 21.0 0.1 0.9 2.2 0.0 0.0 99.5 0.0 0.8 18.7 0.0 0.0 2.5 8.3 0.0 0.0 0.3 0.0 32.9 0.0 0.0 0.0 1.3 4.0 1.2 0.2 10.6 29.0 0.0 29.8 0.0 557.4 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.9 2.6 0.5 0.8 0.0 1.1 0.3 0.2 139.6 0.0 0.0 COL11A2 "DFNA13, DFNB53, HKE5" ENSG00000204248 "Collagen type XI alpha 2 chain" P13942 6 33162681-33192499 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "pituitary gland: 23.5;testis: 8.1" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Early spermatids: 10.8;Muller glia cells: 5.2;Oligodendrocytes: 6.7" "Cancer enriched" "Detected in many" 8 "melanoma: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.62e-1)" "unprognostic (8.69e-2)" "unprognostic (1.65e-4)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (1.04e-2)" "unprognostic (9.67e-2)" "unprognostic (2.05e-2)" "unprognostic (4.47e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-3)" "unprognostic (2.26e-6)" "unprognostic (8.27e-2)" "unprognostic (2.17e-1)" "unprognostic (1.88e-1)" "unprognostic (5.96e-2)" 1.0 0.3 0.3 0.0 0.6 0.0 0.9 0.5 0.6 1.6 0.0 0.7 0.2 1.2 0.2 0.5 0.9 0.1 1.8 0.3 0.3 1.3 0.8 1.0 0.0 0.5 0.4 1.1 0.6 0.1 23.5 0.0 0.5 1.3 0.0 0.1 0.8 0.1 1.3 0.6 0.7 0.1 0.5 1.2 0.7 8.1 0.5 0.3 3.5 0.7 0.0 0.6 0.9 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.2 0.2 0.0 0.0 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.6 0.3 0.3 0.5 0.4 0.5 0.5 0.5 0.8 2.6 0.0 0.0 8.5 0.1 1.5 0.2 0.1 1.8 2.8 1.2 1.8 2.3 0.0 0.1 0.0 4.2 0.0 0.6 0.3 0.0 0.1 10.8 0.2 0.6 1.5 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.5 0.0 0.6 4.6 0.2 0.2 0.0 3.7 0.1 0.0 0.6 0.4 1.9 0.0 0.3 1.8 1.0 0.0 5.2 0.0 3.5 6.7 0.1 0.6 0.4 0.8 0.2 0.0 0.1 0.0 1.1 0.0 0.7 1.8 0.9 2.1 0.7 1.1 0.0 0.4 0.2 0.5 0.1 COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial stromal cells: 44.3;Excitatory neurons: 52.9;Fibroblasts: 99.7;Leydig cells: 60.3;Sertoli cells: 46.0;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "fHDF/TERT166: 1432.1;SiHa: 846.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 29.1" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 9100000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" 105.1 15.7 2.2 16.0 1.9 0.0 65.4 0.8 2.7 112.8 0.4 74.9 8.7 124.5 5.5 36.2 42.2 20.9 25.5 1.0 1.2 25.9 3.5 24.6 7.2 1.8 4.8 123.2 5.9 5.0 4.8 1.8 0.6 20.8 17.2 0.4 16.1 42.4 14.4 48.9 40.6 72.1 0.6 11.4 18.1 4.6 2.0 5.5 19.3 12.5 4.2 26.3 45.8 0.8 0.2 2.2 11.5 0.2 270.2 162.0 28.3 275.4 229.3 186.2 257.3 27.5 0.7 0.0 27.7 1432.1 3.9 59.2 0.5 28.7 174.6 0.2 1.4 0.2 101.1 0.1 97.9 0.3 0.2 234.9 5.0 42.2 50.6 173.6 32.0 0.1 0.0 0.0 29.4 0.2 0.1 0.2 6.4 0.0 15.3 0.1 23.1 0.2 8.9 14.4 0.0 0.0 846.1 21.2 0.3 15.5 131.8 0.5 0.2 78.5 97.0 41.5 91.4 0.1 0.1 0.4 26.4 0.3 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.8 2.7 1.0 1.2 1.8 4.8 0.6 0.6 2.0 0.8 14.2 76.9 5.1 2.3 0.0 20.6 0.6 12.7 5.2 0.4 4.7 7.1 4.1 0.0 4.7 3.7 0.0 0.6 0.0 0.0 0.0 1.4 24.1 6.3 44.3 11.0 0.0 0.0 52.9 4.6 1.3 99.7 2.6 14.1 1.3 0.1 3.3 0.0 0.8 0.0 32.4 0.0 0.0 0.3 18.4 14.7 60.3 1.8 21.4 38.4 0.0 0.0 0.0 19.6 1.2 6.7 0.0 13.2 0.1 1.7 0.0 0.9 1.7 0.0 46.0 20.0 48.6 0.3 0.6 0.6 13.1 0.7 2.5 1.4 0.1 0.3 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 229.2" "Cell type enhanced" "Detected in many" "Adipocytes: 307.0;Endothelial cells: 190.5;Fibroblasts: 202.3;Leydig cells: 326.8;Peritubular cells: 483.3;Theca cells: 333.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 26.4;BJ hTERT+: 55.6;HDLM-2: 24.5;K-562: 18.8;U-2197: 45.6;U-87 MG: 20.6;WM-115: 31.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 44.3" "HPA017913, HPA017915" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 28000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA017913: AB_1847099, HPA017915: AB_1847100" "unprognostic (4.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.09e-1)" "unprognostic (1.09e-2)" "prognostic favorable (5.47e-4)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (3.66e-3)" "unprognostic (8.98e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (3.08e-4)" 84.7 36.9 0.6 50.6 0.9 0.1 46.7 0.8 1.0 31.2 4.0 44.5 12.9 53.8 19.2 26.9 17.3 42.8 58.0 0.4 0.8 12.9 1.0 11.1 10.4 0.6 0.9 23.2 26.8 11.8 6.0 229.2 0.7 21.6 16.3 0.0 35.9 14.3 56.5 15.1 17.7 108.9 0.6 3.7 27.3 27.0 2.4 13.0 21.1 34.4 8.6 42.1 15.1 0.7 0.0 0.0 0.1 0.0 4.6 2.6 0.1 26.4 55.6 1.4 0.5 0.0 0.0 0.2 0.7 5.8 0.2 0.1 0.0 0.0 0.2 24.5 0.0 0.3 12.9 0.0 1.1 0.4 2.5 7.6 0.0 6.0 0.2 0.0 0.0 0.0 18.8 0.0 2.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 14.7 0.2 0.0 0.0 0.1 0.1 0.8 3.9 7.4 0.3 0.2 0.6 0.0 0.1 0.6 45.6 0.5 0.2 0.0 0.0 20.6 0.2 31.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.8 1.0 0.4 0.8 0.6 0.9 0.7 0.6 2.4 0.7 307.0 0.0 0.0 0.7 0.5 19.5 0.1 0.0 5.2 0.0 2.6 4.1 8.1 0.0 0.0 0.0 0.0 3.8 1.8 0.0 0.0 2.4 5.7 3.9 103.4 190.5 0.0 0.0 0.4 0.8 3.7 202.3 0.5 2.2 0.0 0.3 0.0 0.0 7.6 0.0 2.9 0.0 0.0 0.3 27.2 22.5 326.8 3.1 17.8 46.9 0.6 0.0 1.0 1.0 0.3 0.6 0.0 483.3 0.3 1.2 0.0 0.5 0.0 0.0 13.1 107.8 52.8 1.9 1.2 1.3 16.3 7.7 2.1 333.4 0.0 0.7 COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 122.0;Peritubular cells: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 133.1;ASC TERT1: 102.9;BJ hTERT+: 115.9;fHDF/TERT166: 106.5;HSkMC: 98.7;U-2197: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027237 Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA027237: AB_10600699" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" 33.6 17.3 19.0 14.4 44.7 0.3 41.0 35.9 32.4 169.7 7.6 78.9 14.8 93.6 23.7 22.4 37.4 39.4 33.6 18.9 29.8 11.5 3.2 31.1 8.5 55.5 43.2 177.9 7.8 3.5 28.6 21.1 48.6 102.8 10.9 8.8 35.5 91.3 8.4 69.3 35.8 56.2 34.0 9.9 42.1 40.9 40.3 5.6 46.8 7.4 4.1 106.9 86.8 57.5 0.1 2.0 0.0 0.1 133.1 102.9 14.6 60.5 115.9 15.1 16.1 0.4 11.0 0.0 1.9 106.5 2.3 48.3 0.0 65.8 3.5 0.0 0.2 0.0 8.1 21.3 45.1 0.0 0.3 98.7 44.6 43.2 22.7 3.8 0.1 0.3 0.0 0.2 2.1 0.0 0.1 0.5 0.1 0.4 0.2 0.2 1.3 0.4 0.0 0.4 1.5 2.7 7.3 1.2 9.6 0.5 1.2 0.0 0.2 52.3 52.5 92.1 1.3 0.1 0.2 0.0 36.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 44.7 35.9 32.4 18.9 29.8 55.5 43.2 48.6 34.0 40.3 57.5 4.3 9.6 3.9 109.0 0.1 30.7 14.8 37.5 15.9 2.4 7.9 21.3 8.4 0.0 9.8 18.4 2.1 1.9 0.6 2.0 0.0 4.6 13.6 2.6 11.5 2.8 27.6 0.4 23.9 0.7 3.8 54.3 8.2 2.4 7.0 0.2 5.0 0.0 1.3 0.0 8.2 30.9 8.2 0.6 11.4 26.8 43.8 0.7 14.2 10.3 0.0 31.3 0.0 62.4 122.0 1.2 4.7 91.4 0.3 9.3 16.8 2.1 15.0 2.5 0.0 5.4 25.0 14.9 3.8 1.9 21.2 2.2 2.2 0.5 6.8 15.3 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 COL19A1 ENSG00000082293 "Collagen type XIX alpha 1 chain" Q14993 6 69866556-70212468 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.1;lymphoid tissue: 3.2" "Cell type enhanced" "Detected in some" "B-cells: 33.5;Excitatory neurons: 66.6;Inhibitory neurons: 164.2;Oligodendrocyte precursor cells: 39.7" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Region enhanced" "Detected in many" "cerebellum: 9.1" "Group enriched" "Detected in some" 218 "memory B-cell: 14.6;naive B-cell: 31.9" "Lineage enriched" "Detected in single" 299 "B-cells: 31.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.3;RH-30: 11.4;SCLC-21H: 3.7;SH-SY5Y: 2.9;SK-MEL-30: 9.6;WM-115: 9.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA042422 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042422: AB_10794798" "unprognostic (2.65e-2)" "unprognostic (2.55e-1)" "unprognostic (2.71e-1)" "unprognostic (9.24e-2)" "unprognostic (2.26e-2)" "unprognostic (6.20e-2)" "unprognostic (3.17e-1)" "unprognostic (1.10e-3)" "unprognostic (3.41e-1)" "unprognostic (1.28e-1)" "unprognostic (2.76e-1)" "unprognostic (1.62e-2)" "unprognostic (1.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.20e-1)" "unprognostic (3.35e-1)" "unprognostic (8.91e-2)" 0.0 0.1 1.2 1.5 1.6 0.3 0.0 9.1 1.9 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.1 0.1 0.7 2.3 0.1 1.4 0.1 0.0 2.6 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.3 0.7 0.7 0.6 0.1 0.0 0.7 0.0 0.7 0.0 0.0 1.6 1.1 0.4 0.0 1.1 0.0 0.2 3.2 2.2 0.2 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.4 0.0 0.0 0.0 3.7 2.9 0.0 0.0 9.6 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 31.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 1.6 9.1 1.9 2.3 0.1 0.2 0.2 0.3 0.0 0.0 2.1 0.0 0.0 0.0 11.1 33.5 0.1 0.2 0.0 0.0 4.4 0.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 66.6 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.7 0.1 0.0 0.0 164.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.8 8.4 0.3 0.1 1.0 39.7 10.6 0.0 0.0 0.0 0.9 0.0 0.0 3.8 0.7 0.1 0.0 11.2 0.4 1.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL20A1 KIAA1510 ENSG00000101203 "Collagen type XX alpha 1 chain" Q9P218 20 63293186-63334851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.3;choroid plexus: 2.8;testis: 2.5" "Group enriched" "Detected in some" 11 "Oligodendrocyte precursor cells: 72.9;Spermatocytes: 21.8" "Cancer enriched" "Detected in single" 19 "glioma: 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA072382 Uncertain "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 65: Brain - Ion transport" "Cluster 68: Oligodendrocytes - Mixed function" "Endoplasmic reticulum" "HPA072382: " "unprognostic (6.34e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "unprognostic (2.01e-1)" "unprognostic (5.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "unprognostic (1.70e-2)" "unprognostic (1.71e-1)" "unprognostic (2.89e-1)" "unprognostic (8.41e-7)" "unprognostic (7.85e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (1.16e-1)" 0.0 0.2 3.9 0.0 4.0 0.0 0.0 3.0 8.3 0.5 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.9 2.8 0.1 0.0 0.0 0.0 3.7 3.3 0.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 3.3 0.7 0.0 2.5 3.4 0.0 0.0 0.3 0.0 0.0 0.1 5.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 3.0 8.3 3.9 2.8 3.7 3.3 3.6 3.3 3.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 3.3 0.4 0.0 0.0 0.0 0.0 2.7 0.3 0.0 0.0 0.0 0.0 0.4 0.0 72.9 0.3 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.2 0.1 21.8 4.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Cardiomyocytes: 36.9;Extravillous trophoblasts: 75.3;Inhibitory neurons: 63.3;Respiratory ciliated cells: 51.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 23.4;BEWO: 7.6;HSkMC: 24.0;SuSa: 11.1" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" 2.6 1.4 2.6 0.6 3.2 0.0 1.4 3.3 1.9 24.1 11.4 7.8 0.5 12.4 2.8 2.4 7.4 3.8 4.2 2.4 5.6 1.1 1.2 7.6 0.5 2.7 6.3 3.7 1.9 0.6 1.9 28.3 3.1 3.5 2.0 0.0 5.0 10.7 1.3 6.6 1.3 7.9 1.5 0.5 2.7 2.7 4.0 0.7 1.0 6.6 0.5 6.1 6.0 2.7 0.0 3.4 0.2 0.0 1.3 23.4 7.6 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.2 0.1 0.0 24.0 0.9 0.0 0.3 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.2 3.3 1.9 2.4 5.6 2.7 6.3 3.1 1.5 4.0 2.7 6.4 0.0 1.5 66.6 0.0 5.9 2.2 2.8 2.2 0.0 0.3 0.4 36.9 0.0 8.2 0.0 0.0 27.5 0.1 0.0 0.0 0.0 7.4 24.8 10.6 6.6 0.0 0.0 16.0 0.0 75.3 28.2 0.5 1.2 0.0 0.2 2.9 0.0 6.1 0.0 63.3 0.0 16.2 0.3 3.0 1.7 15.2 0.3 5.4 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 12.4 0.0 0.1 0.1 0.1 51.3 0.0 0.0 7.3 15.0 1.2 2.5 1.0 4.1 23.3 0.4 2.1 0.2 1.3 COL22A1 ENSG00000169436 "Collagen type XXII alpha 1 chain" Q8NFW1 8 138588235-138914041 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 44.0" "Cell type enhanced" "Detected in some" "Early spermatids: 39.6;Excitatory neurons: 13.0;Late spermatids: 33.7;Muller glia cells: 25.5" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 29.5;RT4: 12.2;SCLC-21H: 8.1;U-2 OS: 6.8" "Low region specificity" "Detected in many" HPA024830 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA024830: AB_1847102" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (4.19e-6)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.05e-2)" "unprognostic (5.57e-3)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (5.74e-2)" "unprognostic (3.62e-2)" "unprognostic (3.66e-15)" "unprognostic (2.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (1.09e-1)" 0.1 7.6 0.6 0.6 1.0 0.0 0.0 2.9 0.5 0.8 0.4 1.0 0.3 1.9 0.2 0.1 0.4 0.3 0.2 0.3 1.4 1.9 0.0 0.0 0.5 2.9 1.2 0.2 0.1 1.4 44.0 0.0 0.6 3.0 0.1 5.2 0.9 2.4 0.7 0.0 0.4 1.6 4.3 0.2 2.2 1.1 2.0 2.1 0.2 1.1 1.2 0.9 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.2 8.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.9 0.5 0.3 1.4 2.9 1.2 0.6 4.3 2.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 3.7 2.5 0.0 0.3 0.2 0.3 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 39.6 0.1 0.2 0.8 0.0 0.0 13.0 0.2 0.0 0.2 0.0 0.6 0.0 0.6 0.0 0.0 5.9 0.0 0.8 0.0 8.2 0.0 0.0 33.7 0.3 0.3 0.0 1.0 0.6 25.5 0.0 0.5 0.3 3.0 0.0 0.0 0.0 4.8 0.0 0.1 0.2 1.6 0.0 0.1 0.3 2.1 1.7 0.0 0.0 0.0 0.0 0.0 0.1 1.9 COL24A1 ENSG00000171502 "Collagen type XXIV alpha 1 chain" Q17RW2 1 85729233-86156943 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 167.1" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebral cortex: 9.0;hippocampal formation: 8.2" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 2.7" "Lineage enriched" "Detected in single" 9 "dendritic cells: 2.7" "Cell line enhanced" "Detected in some" "ASC diff: 2.1;Karpas-707: 3.7;NTERA-2: 1.9;RH-30: 2.7;SuSa: 2.8;U-266/70: 6.9" "Secreted to extracellular matrix" NA NA 52000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.00e-1)" "unprognostic (6.19e-2)" "unprognostic (2.21e-2)" "unprognostic (6.76e-3)" "unprognostic (1.82e-3)" "unprognostic (2.45e-2)" "unprognostic (2.44e-5)" "unprognostic (1.37e-1)" "unprognostic (4.08e-2)" "unprognostic (6.59e-2)" "unprognostic (3.89e-2)" "unprognostic (1.46e-1)" "unprognostic (3.48e-6)" "unprognostic (2.79e-5)" "unprognostic (5.07e-1)" "unprognostic (1.19e-1)" "unprognostic (9.90e-2)" 0.7 0.0 0.9 0.8 2.7 0.9 0.3 0.0 9.0 6.8 0.0 6.7 1.5 1.2 0.8 0.7 0.1 1.5 1.9 8.2 0.9 0.8 0.0 0.7 0.3 0.0 0.0 2.4 0.0 0.0 1.2 0.1 0.0 1.1 0.8 5.5 0.4 1.4 0.5 0.6 1.7 0.9 0.1 0.3 1.7 0.8 0.0 0.2 0.4 1.7 0.3 5.0 2.9 1.8 0.0 0.0 0.9 0.0 2.1 0.3 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.9 0.0 0.5 0.0 0.7 0.0 0.1 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.5 0.0 0.0 0.1 1.9 0.0 0.0 0.0 2.7 0.3 0.3 0.7 0.0 0.0 0.0 0.1 0.3 2.8 0.0 0.6 0.0 1.2 0.1 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.0 0.0 0.9 2.7 0.0 9.0 8.2 0.9 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.6 6.8 1.1 0.4 0.0 0.2 0.0 1.9 0.5 0.0 2.1 0.0 0.5 5.5 0.0 0.0 11.1 0.0 0.0 0.0 0.1 0.2 3.7 0.4 0.0 2.5 167.1 0.0 0.0 2.8 0.0 0.1 1.3 0.5 0.0 0.0 2.4 0.0 12.9 0.0 0.0 0.0 0.4 0.2 0.9 0.9 10.6 7.5 0.0 40.4 0.0 11.1 6.5 0.0 0.0 0.7 3.3 0.0 0.0 0.1 2.4 1.7 0.0 0.5 1.3 1.0 0.9 0.0 0.1 0.0 0.3 2.8 0.0 0.0 COL26A1 "EMI6, EMID2, Emu2" ENSG00000160963 "Collagen type XXVI alpha 1 chain" Q96A83 7 101362875-101559024 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;liver: 5.5" "Group enriched" "Detected in some" 7 "Excitatory neurons: 68.4;Inhibitory neurons: 18.5" "Group enriched" "Detected in many" 6 "endometrial cancer: 12.6;ovarian cancer: 5.7;prostate cancer: 4.6;testis cancer: 14.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 45 "plasmacytoid DC: 9.2" "Lineage enriched" "Detected in single" 45 "dendritic cells: 9.2" "Cell line enhanced" "Detected in some" "AF22: 30.0;BEWO: 23.9;HAP1: 10.7;NTERA-2: 25.4;SuSa: 19.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027059 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027059: AB_1848142" "unprognostic (5.94e-3)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.66e-1)" "unprognostic (3.35e-1)" "prognostic favorable (2.32e-5)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.26e-3)" "unprognostic (1.78e-1)" "unprognostic (4.24e-3)" "unprognostic (3.60e-1)" "unprognostic (1.50e-1)" "unprognostic (7.48e-4)" "unprognostic (2.83e-3)" 0.1 4.4 5.2 0.1 7.4 0.2 0.1 0.2 12.8 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.0 9.8 1.2 4.9 5.5 0.4 0.5 1.1 0.9 0.4 2.2 3.9 0.9 0.3 0.9 2.2 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.4 0.2 0.3 1.0 2.0 1.2 0.1 0.0 0.1 0.2 0.1 4.2 0.0 0.8 30.0 1.9 0.0 0.0 23.9 0.0 0.0 0.0 0.0 1.3 0.0 0.1 4.7 0.0 0.1 0.0 10.7 0.0 0.0 1.0 1.3 0.0 0.0 7.9 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 25.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.2 19.2 0.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 5.2 7.4 0.2 12.8 9.8 1.2 1.1 0.9 0.9 0.4 2.0 4.2 0.0 0.0 0.0 3.3 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 5.5 0.0 0.3 0.0 0.0 0.0 0.2 1.5 0.1 1.7 0.1 0.0 0.0 68.4 0.6 0.4 0.5 0.0 0.2 0.0 1.0 0.0 3.6 0.1 0.0 18.5 0.0 0.0 0.0 0.0 3.5 0.0 0.5 0.0 5.6 0.0 0.0 0.0 3.5 2.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 2.0 0.0 0.0 0.4 0.0 0.9 0.0 0.4 COL27A1 "FLJ11895, KIAA1870, MGC11337" ENSG00000196739 "Collagen type XXVII alpha 1 chain" Q8IZC6 9 114155537-114312511 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 93.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 60.1;Extravillous trophoblasts: 75.5;Gastric mucus-secreting cells: 43.8;Hepatocytes: 43.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 29.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 54.8;Hep G2: 48.7" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 19 "cerebellum: 71.0" "HPA021884, HPA048471" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" "HPA021884: AB_2670857, HPA048471: AB_2680407" "unprognostic (4.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (7.11e-4)" "unprognostic (4.13e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (6.25e-2)" "unprognostic (1.71e-1)" "unprognostic (1.09e-3)" "unprognostic (3.31e-1)" "unprognostic (3.41e-2)" "unprognostic (2.97e-2)" "unprognostic (9.48e-2)" "unprognostic (6.21e-3)" "unprognostic (3.50e-3)" 9.2 8.7 4.0 3.5 3.4 0.3 9.1 29.6 4.8 93.7 3.0 11.2 3.9 39.7 16.1 8.1 16.7 7.9 10.9 3.6 4.7 33.1 42.7 7.0 3.1 7.0 7.9 27.6 21.2 1.0 4.1 11.7 6.5 22.5 1.4 1.5 5.4 13.7 5.8 15.7 6.9 10.5 4.9 4.7 11.9 6.4 6.4 9.2 13.5 2.8 2.2 8.1 37.7 4.3 3.8 7.8 17.9 6.6 1.3 1.9 54.8 8.7 5.9 6.3 5.2 8.1 0.2 0.0 2.1 4.3 4.7 9.2 6.2 8.1 3.4 0.0 0.7 0.0 7.5 48.7 1.9 0.0 19.8 4.9 2.3 7.6 3.4 3.6 9.4 7.4 0.0 1.9 3.6 1.8 0.1 3.5 6.5 15.1 2.1 25.9 18.1 3.7 14.6 4.2 0.3 0.2 0.4 0.2 1.1 6.8 1.6 5.8 8.9 5.5 11.1 0.7 13.9 1.0 0.0 0.0 4.5 0.1 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 3.4 29.6 4.8 3.6 4.7 7.0 7.9 6.5 4.9 6.4 4.3 2.9 3.2 23.0 15.0 0.8 27.1 4.9 14.2 18.2 1.2 24.3 22.1 34.4 60.1 6.1 9.2 6.2 1.0 2.0 0.5 3.9 12.8 3.7 3.3 25.3 7.1 4.8 0.0 11.0 5.1 75.5 15.0 43.8 11.5 0.0 6.9 3.6 43.6 6.5 1.7 4.6 1.8 0.0 1.0 4.1 1.6 19.3 0.8 23.2 8.4 0.1 5.6 0.0 25.6 0.8 4.7 2.5 4.5 0.4 10.6 0.3 9.8 0.6 1.4 26.3 4.9 40.1 0.5 2.0 5.8 22.4 2.3 1.4 23.8 2.4 3.2 COL28A1 ENSG00000215018 "Collagen type XXVIII alpha 1 chain" Q2UY09 7 7356203-7535873 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.2" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Cone photoreceptor cells: 18.8;Endometrial ciliated cells: 21.1;Excitatory neurons: 23.4;Inhibitory neurons: 22.6;Oligodendrocyte precursor cells: 12.5;Respiratory ciliated cells: 16.3" "Cancer enhanced" "Detected in many" "glioma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 2.3;U-266/70: 9.8;U-266/84: 2.8;WM-115: 4.9" "Region enriched" "Detected in single" 8 "olfactory bulb: 3.6" "Region enriched" "Detected in some" 31 "spinal cord: 33.5" "HPA043844, HPA060468" Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 51: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA043844: AB_2732508, HPA060468: AB_2684288" "unprognostic (6.28e-2)" "unprognostic (2.90e-2)" "unprognostic (1.28e-1)" "unprognostic (8.71e-3)" "unprognostic (1.89e-2)" "unprognostic (5.63e-3)" "unprognostic (2.61e-2)" "unprognostic (7.58e-2)" "unprognostic (2.72e-2)" "unprognostic (7.69e-2)" "unprognostic (3.90e-3)" "unprognostic (2.33e-2)" "unprognostic (3.45e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (2.48e-3)" "unprognostic (3.09e-2)" 1.0 3.2 0.8 1.6 1.0 0.3 2.8 1.9 2.7 3.3 1.4 11.7 1.2 2.2 14.1 2.1 4.9 1.5 3.7 1.1 0.9 6.3 0.7 1.2 0.2 0.9 3.6 1.2 5.8 0.2 11.2 0.5 1.4 3.9 4.1 6.7 18.2 5.1 5.9 2.1 3.4 1.7 0.2 0.4 6.5 3.7 1.1 0.2 1.2 3.2 0.1 2.9 4.5 1.5 1.5 0.0 0.0 0.0 0.1 0.7 0.2 0.1 0.4 0.0 0.0 1.1 0.4 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.2 1.4 0.1 0.2 0.0 0.7 0.9 0.3 0.0 0.1 0.0 2.3 0.0 0.1 0.0 0.1 0.7 0.0 0.3 0.1 0.5 0.7 0.1 0.5 1.3 0.0 9.8 2.8 0.0 0.2 0.6 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.8 1.0 1.9 2.7 1.1 0.9 0.9 3.6 1.4 0.2 1.1 1.5 0.4 0.0 4.1 39.5 0.0 0.3 0.1 0.2 0.0 5.3 1.6 1.5 0.9 0.0 3.3 3.7 18.8 0.3 0.1 0.8 0.0 0.1 2.0 21.1 0.5 0.1 0.0 0.0 23.4 0.2 0.0 3.1 0.0 3.9 1.3 0.5 1.8 0.0 0.1 5.0 22.6 0.5 0.0 0.3 0.3 1.1 0.9 0.1 0.0 7.5 0.0 2.2 0.0 12.5 9.1 0.4 5.4 0.7 0.0 0.1 0.2 0.5 16.3 5.4 0.0 1.8 0.2 0.9 1.0 0.1 0.1 0.3 0.1 0.2 0.3 0.1 COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 19.1;pituitary gland: 9.2;retina: 5.6;stomach 1: 12.5" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Enteroendocrine cells: 43.9;Late spermatids: 9.7;Muller glia cells: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 156.3;HAP1: 98.9;HEK 293: 36.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" No NA 1400000 "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Nucleoplasm "CAB002214: AB_563666, HPA055753: AB_2682908" "unprognostic (7.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.88e-2)" "unprognostic (3.08e-2)" "unprognostic (8.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.31e-4)" "unprognostic (2.64e-1)" "unprognostic (3.44e-3)" "unprognostic (1.89e-1)" "unprognostic (2.93e-1)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.1 0.0 0.2 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.2 0.2 1.3 0.0 0.0 9.2 0.3 0.3 1.0 0.3 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.5 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.7 0.0 0.0 0.0 98.9 0.0 0.0 0.0 36.3 0.2 0.0 5.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 2.9 0.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 11.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.0 0.6 5.7 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 15.4 0.3 0.1 0.2 43.9 0.0 0.2 0.0 0.3 0.5 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 9.7 0.9 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 1.7 0.0 0.9 0.3 0.6 1.1 0.0 0.0 0.8 0.1 0.1 1.7 0.1 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 401.4;Endometrial stromal cells: 312.2;Endothelial cells: 385.9;Extravillous trophoblasts: 672.4;Sertoli cells: 506.2;Smooth muscle cells: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "ASC diff: 501.6;EFO-21: 915.3;TIME: 331.3" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" 348.4 33.6 10.8 135.9 5.2 0.4 130.4 3.7 9.0 65.7 8.9 108.5 24.8 105.3 14.8 40.8 64.1 116.8 81.9 12.6 5.2 53.4 22.1 137.0 27.7 9.1 7.0 27.0 36.0 36.3 12.8 900.3 7.5 53.6 30.4 1.8 19.0 85.6 40.1 25.2 43.4 312.7 6.8 76.3 50.1 10.7 13.7 10.7 54.7 47.0 11.1 120.8 38.2 6.9 40.0 15.2 195.9 0.3 501.6 148.9 274.9 246.2 59.5 134.0 65.3 4.2 0.8 0.1 915.3 46.2 59.7 26.8 0.0 55.8 30.3 1.3 29.5 0.2 28.2 0.0 142.8 0.0 0.4 49.7 8.9 132.8 59.4 212.8 207.7 0.1 0.3 0.2 31.1 0.1 0.1 0.8 28.1 0.2 3.6 0.4 58.6 0.1 278.8 0.0 1.4 29.8 0.1 0.4 61.0 192.4 0.1 13.9 331.3 39.9 121.4 1.0 97.4 0.3 1.8 3.9 0.4 0.7 297.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 10.8 5.2 3.7 9.0 12.6 5.2 9.1 7.0 7.5 6.8 13.7 6.9 401.4 41.7 8.9 5.2 1.9 14.0 9.7 8.5 2.8 1.0 3.5 16.5 41.1 10.0 0.9 23.9 0.0 49.7 0.5 0.1 1.9 22.6 0.7 19.8 312.2 385.9 0.0 0.0 10.5 0.2 672.4 211.8 1.5 48.7 1.3 215.8 134.6 1.3 27.7 0.0 18.9 0.5 0.0 4.4 19.2 2.8 38.5 4.2 30.2 36.5 0.6 2.5 0.0 1.0 0.9 0.6 0.1 109.4 0.5 6.2 0.5 26.7 2.8 0.4 506.2 142.8 415.1 1.2 5.0 0.8 15.2 45.0 4.2 45.9 0.6 2.2 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 52.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Bipolar cells: 62.1;Cone photoreceptor cells: 398.2;Muller glia cells: 143.1;Oligodendrocyte precursor cells: 84.9" "Group enriched" "Detected in some" 6 "lung cancer: 1.7;renal cancer: 3.0;thyroid cancer: 5.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cell line enhanced" "Detected in some" "HeLa: 18.8;hTERT-RPE1: 14.5;Karpas-707: 9.9;RPTEC TERT1: 11.0;U-266/70: 9.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA042064: AB_10794410" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-6)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (1.84e-2)" "unprognostic (7.07e-3)" "unprognostic (2.30e-1)" "unprognostic (9.09e-3)" "unprognostic (9.30e-2)" "unprognostic (3.02e-2)" "prognostic favorable (2.51e-7)" "unprognostic (1.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" 0.6 11.5 1.9 2.1 1.8 0.3 1.0 1.5 1.7 0.4 21.5 0.8 0.7 1.2 16.3 1.0 2.1 3.2 8.9 1.4 2.0 30.5 0.6 15.0 2.9 3.3 3.1 3.9 5.0 0.2 16.2 0.2 2.7 6.0 1.0 52.9 1.2 9.9 22.2 0.5 6.7 0.8 1.6 7.2 1.8 1.7 6.3 0.4 20.5 15.2 5.6 1.4 1.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.0 0.3 1.1 0.1 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 1.2 0.0 9.9 0.0 0.4 0.0 0.1 1.4 0.0 0.0 0.1 0.0 3.2 11.0 2.3 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 9.0 3.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 1.5 1.7 1.4 2.0 3.3 3.1 2.7 1.6 6.3 2.2 0.5 169.9 31.7 3.9 14.0 0.1 0.1 0.1 0.6 62.1 0.1 0.9 2.6 1.5 9.3 42.3 398.2 0.1 0.1 0.0 0.0 0.1 0.7 0.1 0.2 2.4 0.0 0.0 5.5 1.0 0.0 4.6 0.5 0.3 1.3 22.8 0.4 0.2 0.0 1.7 14.1 0.0 0.0 0.0 0.3 0.3 8.4 0.3 1.8 13.1 0.0 143.1 0.0 84.9 3.6 1.0 0.0 12.0 8.0 0.1 0.0 1.9 0.1 11.9 13.1 11.7 3.6 0.4 0.0 0.3 0.3 0.0 1.2 0.1 0.0 0.0 COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Collecting duct cells: 46.0;Cone photoreceptor cells: 56.3;Granulosa cells: 62.6;Muller glia cells: 78.6;Oligodendrocyte precursor cells: 55.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 34.3;hTERT-RPE1: 27.2;Karpas-707: 8.9;RPTEC TERT1: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" 1.0 6.9 1.3 2.1 1.1 0.1 0.7 0.9 0.9 0.5 14.2 0.9 0.9 2.0 7.2 1.1 2.1 4.4 9.2 1.0 1.3 14.0 1.6 8.3 2.8 3.1 2.2 2.0 5.5 0.6 10.2 0.3 2.6 4.5 0.8 8.4 0.7 8.3 6.9 0.3 2.4 1.6 1.5 1.9 1.2 1.3 4.4 0.9 9.9 5.7 4.5 2.9 0.9 1.3 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.1 0.6 0.0 0.7 0.0 1.7 0.0 0.7 0.1 3.1 1.1 0.2 0.0 3.4 0.0 34.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 27.2 0.0 1.1 0.0 8.9 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 14.5 5.6 0.8 0.0 2.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 2.7 0.0 0.3 6.7 5.3 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.3 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.1 0.9 0.9 1.0 1.3 3.1 2.2 2.6 1.5 4.4 1.3 2.0 73.7 24.1 3.6 11.1 0.5 0.4 0.2 0.0 29.1 0.5 1.3 3.5 8.6 6.2 46.0 56.3 0.0 1.4 0.1 1.9 0.3 0.8 0.3 1.8 5.2 1.2 0.0 2.5 3.8 0.0 8.1 1.5 0.9 0.0 62.6 2.5 0.7 0.1 0.0 10.4 0.1 2.0 0.3 1.5 4.3 25.1 0.8 0.0 12.2 0.0 78.6 0.0 55.3 3.4 4.1 0.1 27.1 14.9 0.2 0.0 3.6 0.0 8.5 0.0 16.8 8.6 0.1 0.6 0.2 0.0 0.0 1.4 0.9 0.3 0.1 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.6;urinary bladder: 40.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 24.5;Basal respiratory cells: 16.0;Cardiomyocytes: 13.1;Prostatic glandular cells: 12.1;Urothelial cells: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.0;HeLa: 40.1;HHSteC: 59.2;hTERT-HME1: 44.1;HUVEC TERT2: 41.7;TIME: 94.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Endoplasmic reticulum" "HPA065393: AB_2685483" "unprognostic (8.47e-3)" "unprognostic (4.50e-3)" "unprognostic (9.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.72e-1)" "unprognostic (9.84e-2)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (8.54e-3)" "unprognostic (3.51e-1)" 3.0 0.5 0.3 0.4 0.3 0.0 2.0 0.2 0.2 12.6 1.3 1.9 1.4 32.6 17.0 5.5 14.9 13.3 5.4 0.3 0.7 4.2 0.1 1.0 0.1 0.9 1.7 9.3 0.1 5.5 7.2 3.2 1.0 12.5 2.1 1.2 1.4 21.5 1.4 6.5 1.5 24.5 0.4 1.4 13.3 1.2 0.3 0.9 0.7 1.2 0.1 40.7 9.2 0.6 0.1 31.1 9.9 0.0 24.2 1.7 0.0 0.0 1.8 0.3 0.2 17.9 0.0 0.0 0.0 0.0 3.9 5.8 10.3 46.0 0.8 0.4 8.8 0.8 40.1 0.3 59.2 0.0 0.0 2.6 27.8 6.5 44.1 0.1 41.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 14.0 0.0 3.8 0.0 0.0 0.0 1.9 3.4 0.0 0.0 2.4 0.0 0.0 18.2 0.9 0.0 94.2 0.0 0.1 5.5 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.2 0.3 0.7 0.9 1.7 1.0 0.4 0.3 0.6 0.1 0.0 0.0 6.2 0.0 6.4 24.5 16.0 3.4 0.2 2.3 6.1 13.1 0.0 2.6 1.8 0.0 0.1 0.0 0.0 1.9 0.0 2.1 0.7 6.0 0.4 0.0 0.0 0.4 0.0 0.0 6.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 2.0 0.0 0.3 0.3 4.1 0.0 0.0 8.4 0.0 5.5 0.0 0.0 0.6 0.1 0.0 9.1 0.0 12.1 0.0 0.0 2.2 0.4 0.0 0.4 7.2 0.2 0.2 0.1 3.7 0.0 0.1 0.8 0.0 15.2 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Astrocytes: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 38.9;BJ: 23.6;BJ hTERT+: 26.2;BJ hTERT+ SV40 Large T+: 14.4;HSkMC: 28.2;WM-115: 26.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" 47.4 5.0 33.2 9.9 33.2 0.1 32.3 30.6 45.9 44.9 43.6 19.3 3.7 27.3 1.9 9.0 22.8 4.1 33.5 33.3 26.4 7.9 13.4 14.2 3.2 35.2 30.2 6.3 5.2 3.0 3.5 32.8 32.3 16.6 2.0 21.1 7.3 8.9 15.3 21.7 11.7 10.3 31.0 1.7 9.9 4.7 30.2 4.5 12.7 6.0 3.9 12.6 26.4 28.4 0.0 0.0 0.5 0.0 12.4 38.9 0.0 23.6 26.2 14.4 5.7 0.0 0.0 0.0 0.2 4.4 0.3 2.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 28.2 0.6 5.2 5.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.1 0.0 0.0 0.0 11.6 5.5 0.5 0.0 0.0 0.0 0.0 1.5 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 33.2 30.6 45.9 33.3 26.4 35.2 30.2 32.3 31.0 30.2 28.4 13.7 0.0 0.0 510.3 0.0 4.2 0.1 0.2 2.2 65.1 0.3 0.9 6.4 0.0 0.1 0.0 6.2 0.1 0.3 1.3 0.0 0.2 6.9 0.4 12.0 8.1 0.0 0.0 15.6 0.0 0.2 17.5 0.5 0.4 0.0 0.0 3.9 22.9 0.6 3.3 3.4 0.0 0.0 0.0 3.2 2.1 17.4 0.4 14.2 36.5 0.1 2.6 0.0 73.9 2.5 0.3 0.1 8.2 0.0 0.3 0.2 0.1 0.9 28.3 92.1 8.5 58.0 0.3 0.3 3.2 7.1 0.1 1.9 0.9 0.0 0.3 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 453.2;Fibroblasts: 1455.4;Leydig cells: 605.5;Peritubular cells: 472.1;Smooth muscle cells: 555.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 1155.7;ASC TERT1: 2116.9;BJ: 1073.7;BJ hTERT+: 982.8;fHDF/TERT166: 775.0;HHSteC: 1129.2;HSkMC: 1524.4;U-138 MG: 1128.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.6" "HPA007029, HPA030920, HPA038799" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 8200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: AB_1078549, HPA030920: AB_2673659, HPA038799: AB_2676214" "unprognostic (3.53e-1)" "unprognostic (3.76e-2)" "unprognostic (3.20e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.11e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.72e-14)" "unprognostic (2.13e-2)" "unprognostic (7.61e-2)" "unprognostic (2.31e-2)" "unprognostic (2.22e-3)" 732.4 96.2 10.1 219.9 10.8 4.5 455.0 8.7 14.4 873.3 21.6 1287.5 97.7 1001.7 36.5 178.8 675.1 283.8 484.3 10.0 14.9 96.5 97.6 394.2 55.7 14.0 19.4 723.6 78.6 24.0 112.2 335.3 11.2 569.9 60.2 0.9 156.2 274.6 123.4 390.6 402.2 275.4 9.8 175.1 441.6 77.0 11.7 35.6 201.3 67.2 25.6 918.6 595.9 12.3 9.4 12.5 34.8 31.2 1155.7 2116.9 10.0 1073.7 982.8 265.5 121.5 2.3 42.4 0.2 79.2 775.0 170.8 0.9 8.1 0.7 21.7 0.8 12.3 0.2 0.2 0.2 1129.2 0.5 4.8 1524.4 0.2 503.6 10.2 0.1 0.6 0.6 0.6 0.8 108.7 5.2 0.4 2.4 19.3 0.0 130.5 0.4 66.9 1.8 0.0 0.1 1.1 54.2 41.6 0.6 0.7 19.4 1.2 6.6 0.2 1128.1 131.5 421.5 270.3 0.7 0.4 0.9 578.1 0.5 164.8 0.0 0.0 0.0 4.5 0.0 3.1 0.0 0.4 2.4 0.0 0.0 0.4 1.2 0.0 0.3 0.0 0.0 0.1 0.5 10.1 10.8 8.7 14.4 10.0 14.9 14.0 19.4 11.2 9.8 11.7 12.3 127.3 3.2 0.6 2.0 3.1 164.4 4.3 0.6 9.1 0.7 12.7 33.5 8.7 4.3 0.6 7.3 0.0 17.6 41.2 0.4 0.0 15.1 4.0 13.2 453.2 101.4 0.0 2.7 0.1 0.4 25.1 1455.4 13.3 10.3 0.0 36.1 123.1 1.4 35.3 0.0 0.8 0.1 0.0 3.1 219.7 23.7 605.5 11.7 181.5 44.0 2.4 3.1 32.0 0.0 0.1 5.9 1.0 472.1 12.1 11.2 0.0 0.4 0.1 0.5 295.9 284.8 555.2 3.7 11.5 4.6 140.4 40.4 32.7 125.3 0.4 3.9 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL6A5 "COL29A1, FLJ35880, VWA4" ENSG00000172752 "Collagen type VI alpha 5 chain" 3 130345516-130484844 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lung: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 6 "Basal keratinocytes: 3.4;Early spermatids: 5.6;Erythroid cells: 3.8;Fibroblasts: 5.5;Langerhans cells: 5.2;Late spermatids: 3.0;Suprabasal keratinocytes: 3.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 64 "HDLM-2: 15.8" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043138 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA043138: AB_10796687" "unprognostic (3.45e-2)" "unprognostic (4.08e-2)" "unprognostic (6.01e-3)" "unprognostic (2.32e-1)" "unprognostic (3.42e-2)" "unprognostic (1.46e-6)" "unprognostic (8.44e-2)" "unprognostic (2.07e-3)" "unprognostic (2.47e-1)" "unprognostic (1.71e-1)" "unprognostic (7.58e-8)" "unprognostic (3.85e-2)" "unprognostic (4.51e-1)" "unprognostic (1.54e-1)" "unprognostic (2.79e-2)" 0.0 0.0 0.0 0.1 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.7 0.0 0.0 0.0 1.0 0.8 0.1 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.3 0.0 3.8 0.2 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.2 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 3.4 0.0 0.2 0.0 0.0 0.0 COL6A6 ENSG00000206384 "Collagen type VI alpha 6 chain" A6NMZ7 3 130560334-130678155 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "parathyroid gland: 97.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Fibroblasts: 20.6;Inhibitory neurons: 5.3;Oligodendrocytes: 4.6;Skeletal myocytes: 3.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SuSa: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "spinal cord: 10.0" HPA045239 Uncertain "Secreted to extracellular matrix" NA NA 700000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA045239: AB_2679268" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (9.91e-2)" "unprognostic (2.08e-4)" "unprognostic (2.79e-1)" "unprognostic (1.11e-5)" "unprognostic (3.74e-3)" "unprognostic (5.59e-2)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (8.90e-2)" "unprognostic (2.70e-1)" "unprognostic (2.96e-4)" "unprognostic (5.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (1.07e-1)" 1.8 0.0 0.0 0.0 0.2 0.2 2.5 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.3 0.9 0.3 0.1 3.3 0.0 0.0 0.0 0.8 7.3 0.0 0.0 0.0 0.2 0.0 97.8 3.6 0.7 0.0 0.0 0.0 0.3 1.5 0.0 0.1 0.4 0.0 0.5 0.0 1.2 0.1 0.4 0.1 1.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 1.1 1.3 0.0 0.9 0.0 0.0 0.0 1.1 0.2 0.4 2.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 2.9 0.1 0.0 0.0 4.6 0.0 0.0 20.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 0.0 0.0 0.0 1.5 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 3.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 3.3 0.8 0.0 0.4 0.0 0.9 0.1 0.2 0.0 0.0 0.0 COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 72.5;Basal respiratory cells: 59.3;Basal squamous epithelial cells: 67.2;Endometrial stromal cells: 45.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 65.7;HaCaT: 63.5;HBEC3-KT: 100.6;HDLM-2: 97.8;HeLa: 146.2;SiHa: 82.8" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" 0.8 1.1 1.4 3.8 1.0 0.1 4.9 2.8 2.1 24.3 0.4 2.9 1.7 12.1 6.7 21.8 6.4 4.0 3.2 0.3 6.5 7.4 1.3 1.7 1.2 7.0 3.2 3.4 0.4 0.0 2.5 1.6 3.0 34.2 0.9 1.4 11.5 12.2 3.5 98.2 4.1 2.5 2.6 6.5 2.1 3.6 6.5 1.2 0.5 0.6 1.3 6.6 29.2 0.6 0.2 25.4 1.2 0.5 9.2 12.3 31.0 65.7 40.8 16.9 10.0 0.4 0.5 0.1 2.0 15.0 15.4 63.5 0.0 100.6 3.1 97.8 0.5 0.2 146.2 4.3 25.6 0.0 0.4 19.9 58.8 34.4 26.8 23.1 0.0 0.7 0.5 0.7 2.0 0.3 0.0 0.9 3.1 1.3 1.3 0.5 2.2 0.2 9.2 0.2 0.2 0.2 82.8 0.1 0.8 3.7 1.3 0.3 0.0 5.6 3.2 3.2 50.1 1.8 1.8 0.1 49.0 0.4 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 2.8 2.1 0.3 6.5 7.0 3.2 3.0 2.6 6.5 0.6 0.4 0.0 0.0 10.7 0.2 72.5 24.1 59.3 67.2 17.7 1.0 10.2 6.6 0.0 10.6 11.0 10.4 1.4 0.1 0.6 0.0 0.9 11.8 3.1 45.3 1.4 1.8 0.0 6.8 0.7 1.0 8.3 1.1 4.0 0.0 0.8 0.4 0.7 1.6 8.4 11.6 0.7 0.0 0.3 4.2 6.3 5.0 0.8 8.8 8.4 0.1 2.6 0.0 4.0 4.4 15.6 0.1 5.7 0.0 5.7 0.2 0.3 2.5 12.9 0.0 2.0 13.4 2.6 1.5 11.3 24.2 1.2 0.8 5.0 0.2 5.8 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.2;Cardiomyocytes: 13.5;Fibroblasts: 13.4;Macrophages: 6.8;Melanocytes: 7.2;Microglial cells: 8.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.8;fHDF/TERT166: 4.3;HHSteC: 14.1;hTERT-RPE1: 18.2;THP-1: 4.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.6" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" 5.2 1.2 2.5 4.4 2.2 0.5 5.6 6.1 2.4 9.0 18.3 5.9 1.4 5.7 1.6 5.8 4.2 4.8 5.4 2.3 2.9 1.1 0.6 4.6 3.1 9.0 4.2 3.3 0.8 0.7 4.0 12.8 7.1 6.1 2.0 0.4 7.4 11.4 0.6 5.5 2.4 3.7 6.1 8.5 9.1 0.9 4.2 4.9 7.5 2.1 3.5 13.3 5.9 5.7 0.0 0.0 0.0 0.0 0.5 1.0 0.1 5.8 1.7 1.6 0.9 0.2 0.1 0.0 0.8 4.3 0.0 0.3 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 14.1 0.0 0.0 1.7 0.1 0.7 0.0 18.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.1 0.1 0.0 0.5 0.5 0.5 0.0 0.2 0.4 0.0 4.7 0.1 2.3 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.5 2.2 6.1 2.4 2.3 2.9 9.0 4.2 7.1 6.1 4.2 5.7 0.6 0.0 1.8 0.3 0.0 2.2 2.2 1.8 0.0 0.1 1.3 10.2 13.5 0.0 0.7 0.0 0.0 0.4 1.4 0.0 0.0 0.4 0.1 0.2 0.2 0.7 0.0 0.0 0.2 0.2 0.3 13.4 0.5 0.3 2.5 0.5 1.1 0.0 6.2 0.0 0.4 0.0 0.0 2.0 2.7 0.2 3.1 6.8 7.2 8.4 1.2 0.3 0.0 0.5 0.1 0.6 0.0 6.0 0.1 5.3 0.0 0.0 0.2 0.2 6.6 0.7 1.4 0.0 0.3 0.1 1.3 0.8 1.2 0.3 0.0 0.4 COL9A1 ENSG00000112280 "Collagen type IX alpha 1 chain" P20849 6 70216040-70303084 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 68.8" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 310.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 25.7;NTERA-2: 8.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA074749 Enhanced "Secreted to extracellular matrix" NA NA 120000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA074749: AB_2732266" "unprognostic (2.18e-2)" "unprognostic (2.16e-1)" "unprognostic (2.25e-2)" "unprognostic (3.48e-3)" "unprognostic (5.72e-2)" "unprognostic (5.32e-4)" "unprognostic (3.24e-3)" "unprognostic (8.79e-2)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "unprognostic (1.54e-1)" "unprognostic (2.09e-1)" "unprognostic (2.78e-1)" "unprognostic (3.62e-2)" 0.2 0.0 5.1 0.1 5.3 0.0 0.1 4.5 5.6 0.8 68.8 1.3 0.8 0.3 0.1 0.1 0.2 0.3 9.1 5.6 5.7 1.2 0.0 0.0 0.0 7.1 5.8 0.0 0.3 0.1 5.1 0.0 6.0 15.2 0.5 9.5 1.5 0.3 0.0 0.1 0.9 0.2 5.1 0.0 1.5 4.1 5.3 0.1 0.4 0.3 0.0 1.3 2.9 6.3 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 5.3 4.5 5.6 5.6 5.7 7.1 5.8 6.0 5.1 5.3 6.3 0.6 0.0 0.0 2.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.1 3.7 0.0 0.0 0.0 4.2 0.0 0.0 1.0 1.9 0.0 21.4 1.2 0.1 0.8 1.2 0.0 1.4 0.2 0.0 0.5 0.0 1.7 0.0 1.0 0.0 0.0 0.1 35.3 6.7 0.5 0.0 0.0 0.0 11.6 0.0 0.1 0.0 2.8 0.1 68.5 0.0 310.1 0.6 0.0 0.8 0.4 0.0 2.3 0.0 0.1 0.0 3.2 0.0 0.3 4.2 0.6 2.3 0.1 0.0 0.0 0.0 0.1 0.8 0.1 COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300489-40317813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.2;pituitary gland: 108.1" "Cell type enhanced" "Detected in many" "Muller glia cells: 295.4;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 128.1" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 3.2;myeloid DC: 1.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.2;granulocytes: 3.2" "Group enriched" "Detected in many" 4 "HDLM-2: 98.6;Hep G2: 27.6;HMC-1: 90.3;THP-1: 105.0" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 510000 "Cluster 52: Eosinophils - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles Nucleoplasm "HPA056316: AB_2683099, HPA075286: AB_2732288" "unprognostic (1.42e-2)" "unprognostic (3.54e-2)" "unprognostic (8.94e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.46e-2)" "unprognostic (1.83e-3)" "unprognostic (2.06e-2)" "unprognostic (9.00e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (2.26e-1)" "unprognostic (1.16e-3)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (5.89e-2)" "unprognostic (1.71e-2)" 2.2 3.4 42.6 3.7 71.5 10.9 5.9 58.9 51.1 12.1 21.6 6.5 5.8 5.0 1.7 1.6 11.4 8.5 2.2 38.2 49.7 24.6 0.9 4.3 5.9 65.9 74.1 1.3 2.3 21.0 108.1 1.1 66.2 13.7 3.1 23.1 16.3 24.2 0.2 4.6 10.4 1.4 52.0 9.8 16.5 2.6 58.6 1.8 12.2 0.3 3.1 12.1 2.0 86.2 12.0 0.3 1.8 0.8 2.6 1.3 7.8 0.0 0.0 0.6 1.3 0.4 6.8 3.4 10.0 0.3 0.0 2.0 0.1 0.0 0.3 98.6 1.4 2.0 0.8 27.6 1.5 0.9 90.3 4.8 0.0 0.1 0.0 0.7 0.0 1.5 0.1 19.8 0.0 2.7 1.2 2.1 2.2 0.0 1.2 2.3 0.0 6.9 0.0 14.3 1.4 2.3 0.1 11.8 1.3 6.6 15.0 105.0 0.1 0.0 11.6 0.2 0.4 1.4 0.2 3.4 1.0 12.3 0.6 0.0 0.1 3.2 0.0 0.2 0.0 0.2 0.1 0.0 1.2 0.2 0.0 0.0 0.5 0.2 0.3 0.1 0.1 0.0 42.6 71.5 58.9 51.1 38.2 49.7 65.9 74.1 66.2 52.0 58.6 86.2 0.5 0.0 3.3 26.1 10.8 1.0 3.0 8.5 0.0 2.0 7.1 9.7 1.0 7.2 10.0 25.8 0.0 3.2 2.5 7.2 0.0 11.7 0.2 13.6 0.9 0.6 12.7 0.4 0.3 0.8 0.6 2.1 26.0 20.0 26.1 1.6 1.1 0.0 3.4 0.0 0.3 6.6 2.0 0.3 22.4 0.9 2.1 6.4 1.8 3.7 22.1 295.4 1.0 62.4 128.1 4.9 9.6 0.0 4.0 6.1 5.0 0.3 12.9 10.9 0.0 1.3 1.8 3.4 6.2 0.2 0.6 1.4 2.7 1.8 13.4 13.4 COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7;choroid plexus: 34.4;thyroid gland: 25.4" "Cell type enhanced" "Detected in many" "Early spermatids: 116.6;Late spermatids: 401.9;Muller glia cells: 95.8;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 68.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 143.4;Hep G2: 59.6;SK-MEL-30: 51.1;WM-115: 57.8" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Intermediate filaments" "HPA040125: AB_10805604, HPA058323: AB_2683679" "unprognostic (1.14e-3)" "unprognostic (2.14e-2)" "unprognostic (3.93e-1)" "unprognostic (1.21e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.24e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-1)" 1.6 1.5 17.5 0.7 35.7 0.0 2.8 22.4 21.6 3.3 34.4 12.1 0.7 1.2 0.2 1.3 1.7 0.1 6.3 13.0 16.5 2.9 0.6 0.4 0.2 37.4 31.0 1.7 7.6 0.1 14.0 0.5 24.2 3.2 0.1 1.6 23.6 1.2 0.5 1.9 3.1 0.1 20.5 0.3 2.7 20.7 31.6 0.1 25.4 0.0 0.0 2.8 3.8 39.7 0.2 0.3 0.3 0.2 0.0 0.8 143.4 0.1 0.0 0.1 0.0 1.6 0.2 0.0 13.1 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.9 0.0 8.2 59.6 0.3 0.0 0.5 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.0 0.0 1.0 0.7 6.4 8.2 0.0 2.5 0.0 1.8 0.0 0.1 0.0 1.5 0.2 0.1 51.1 4.6 0.2 5.4 0.0 0.0 0.7 0.1 1.0 0.2 0.1 0.0 0.2 0.0 57.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 35.7 22.4 21.6 13.0 16.5 37.4 31.0 24.2 20.5 31.6 39.7 1.6 3.2 0.0 1.0 26.1 3.2 2.2 1.2 1.8 0.9 2.1 2.5 1.6 0.0 0.2 5.5 10.4 5.1 0.4 0.7 1.9 3.6 116.6 2.7 0.4 3.7 4.2 1.3 2.5 0.0 46.4 15.3 6.1 0.7 0.0 0.6 2.5 6.8 2.2 0.0 2.0 3.3 0.0 2.2 0.9 401.9 4.1 1.7 3.6 0.0 0.5 95.8 0.0 84.9 68.9 0.1 7.3 1.5 44.0 1.2 2.3 23.7 2.5 3.7 0.0 0.8 1.0 2.9 7.8 0.9 7.0 4.0 1.4 3.7 2.0 1.0 COLEC10 CL-L1 ENSG00000184374 "Collectin subfamily member 10" Q9Y6Z7 8 118995452-119108455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 65.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.9;Hepatic stellate cells: 10.4;Inhibitory neurons: 5.4;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 4.8" "Cancer enhanced" "Detected in some" "liver cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 3.4;SK-BR-3: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 30000000 "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (3.79e-4)" "unprognostic (6.25e-3)" "unprognostic (1.80e-3)" "unprognostic (7.73e-2)" "prognostic favorable (5.79e-4)" "unprognostic (1.05e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.25e-2)" "unprognostic (9.02e-5)" "unprognostic (2.47e-1)" "unprognostic (1.82e-1)" "unprognostic (5.85e-5)" "unprognostic (7.12e-2)" 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.6 0.1 0.4 0.4 65.7 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 10.9 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 6.9 0.0 0.2 1.0 0.0 0.0 0.0 0.0 10.4 0.4 0.3 0.0 5.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.8 0.1 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 COLEC11 "CL-K1, MGC3279" ENSG00000118004 "Collectin subfamily member 11" Q9BWP8 2 3594832-3644644 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.2;liver: 143.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 37.4;Hepatic stellate cells: 89.3;Peritubular cells: 52.3;Proximal tubular cells: 127.1;Sertoli cells: 72.3" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HHSteC: 135.7;SH-SY5Y: 111.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA035241 Uncertain "Secreted to blood" NA NA 130000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035241: AB_10600701" "unprognostic (3.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" "unprognostic (1.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.95e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.96e-2)" "unprognostic (2.26e-1)" "unprognostic (9.27e-3)" "unprognostic (7.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.60e-1)" 13.8 40.6 1.0 0.9 1.0 1.9 3.3 4.8 1.9 1.8 6.9 2.8 3.5 1.2 0.4 1.6 4.4 54.2 46.6 1.4 0.9 24.8 143.1 2.4 1.9 1.3 0.5 46.4 13.8 1.2 5.8 2.4 1.3 3.3 0.6 0.5 0.6 1.1 0.6 1.4 3.8 1.1 0.4 3.8 3.1 7.4 1.1 4.0 17.0 0.8 0.2 7.1 1.0 1.3 0.2 1.4 0.7 2.5 0.0 0.0 11.7 0.7 0.0 0.3 0.2 0.7 0.2 0.3 4.0 0.1 0.4 0.4 0.1 0.4 0.3 0.2 0.8 0.6 1.4 5.0 135.7 0.2 1.0 1.6 0.1 0.2 0.0 0.4 0.1 0.8 11.1 0.8 0.0 0.1 0.0 0.8 0.6 0.2 0.9 0.0 0.0 0.5 0.0 0.3 2.1 111.7 1.6 1.1 0.8 0.3 0.5 1.0 0.0 0.0 0.7 0.6 0.5 3.2 26.2 1.5 0.3 1.3 0.6 0.7 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.2 0.9 0.3 0.1 0.2 0.1 0.0 1.0 1.0 4.8 1.9 1.4 0.9 1.3 0.5 1.3 0.4 1.1 1.3 7.3 0.0 0.0 0.7 0.6 1.0 0.0 0.0 2.8 0.5 0.1 0.3 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.1 17.6 0.0 0.3 1.1 22.0 4.2 0.0 0.0 2.2 0.0 1.4 37.4 0.0 0.6 0.0 1.3 89.3 7.9 2.5 0.0 0.9 0.1 0.0 1.9 0.3 0.5 7.5 0.8 3.6 1.0 0.0 1.4 0.0 0.5 0.2 0.1 0.0 52.3 0.0 0.2 0.0 127.1 0.0 0.1 72.3 0.3 18.0 1.3 11.6 0.6 0.9 1.2 0.7 27.0 0.0 0.1 COLQ EAD ENSG00000206561 "Collagen like tail subunit of asymmetric acetylcholinesterase" Q9Y215 3 15450133-15521751 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Neurotransmitter degradation" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 17.3;Excitatory neurons: 45.1;Inhibitory neurons: 46.3;Late spermatids: 16.6;NK-cells: 15.5;Oligodendrocyte precursor cells: 18.1;Oligodendrocytes: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 60.9" "Lineage enriched" "Detected in many" 34 "T-cells: 60.9" "Group enriched" "Detected in some" 6 "BEWO: 11.5;HDLM-2: 3.8;U-937: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045876 Approved "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA045876: AB_2679479" "unprognostic (4.08e-3)" "unprognostic (2.61e-2)" "unprognostic (2.13e-3)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (4.62e-2)" "unprognostic (1.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (1.28e-3)" "unprognostic (4.68e-1)" "unprognostic (7.00e-5)" "unprognostic (6.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-4)" 2.5 2.3 3.1 0.7 3.2 0.8 2.2 3.9 4.6 4.6 11.9 3.7 1.0 3.4 1.6 0.9 8.8 1.1 17.9 3.7 2.7 2.9 3.4 2.5 3.9 4.8 3.2 3.6 1.7 3.6 5.7 0.3 2.8 4.6 0.5 0.6 1.5 0.8 10.8 1.6 2.6 0.7 2.6 7.2 2.4 5.0 2.3 2.6 2.6 5.1 3.0 2.2 2.4 2.9 0.1 0.0 0.7 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 3.8 0.4 0.2 0.5 0.0 0.0 0.1 0.3 0.4 0.0 0.3 0.1 0.2 0.3 0.5 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.0 0.2 1.0 0.0 0.0 0.2 0.5 0.6 0.0 0.0 0.1 0.2 0.2 0.1 0.8 0.4 0.0 0.0 5.2 0.1 0.0 0.6 0.0 9.9 0.0 60.9 0.0 5.3 7.4 0.0 0.0 0.5 0.6 0.0 1.8 0.0 0.4 0.3 3.5 3.1 3.2 3.9 4.6 3.7 2.7 4.8 3.2 2.8 2.6 2.3 2.9 0.6 0.0 0.6 17.3 0.5 0.3 0.2 0.1 0.0 0.3 0.4 0.6 0.7 0.0 1.4 0.0 0.0 0.3 7.7 0.0 0.0 0.1 4.1 6.5 1.4 0.4 1.2 0.4 45.1 0.0 0.2 0.6 1.1 0.8 0.0 3.3 1.8 0.8 0.2 6.7 46.3 0.2 2.0 0.6 0.0 16.6 1.8 0.4 0.0 7.5 0.4 0.3 15.5 18.1 18.3 0.2 0.1 4.5 2.0 0.2 0.0 0.2 4.3 0.7 0.0 0.5 0.7 1.5 0.5 0.0 0.1 2.3 4.1 1.4 0.3 0.1 COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 77.6;heart muscle: 65.3;skin 1: 80.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 19.3;Early spermatids: 37.0;Fibroblasts: 32.0;Glandular and luminal cells: 32.0;Late spermatids: 75.3;Spermatocytes: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 859.6" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA077555: " "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (9.08e-5)" "prognostic unfavorable (2.04e-4)" "unprognostic (8.05e-2)" "unprognostic (8.45e-2)" "unprognostic (3.62e-2)" "unprognostic (5.12e-2)" "unprognostic (1.65e-1)" "unprognostic (1.55e-2)" "unprognostic (2.18e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (1.52e-6)" "unprognostic (5.96e-3)" "unprognostic (1.44e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (6.95e-4)" 77.6 0.2 0.0 1.1 0.2 0.0 11.0 1.3 0.2 7.5 0.0 2.3 0.0 4.6 7.6 9.5 1.2 16.1 65.3 0.0 0.0 5.2 0.3 8.0 3.6 0.3 0.1 0.4 2.8 2.2 0.4 8.2 0.1 10.2 0.0 0.0 14.1 6.7 18.0 80.6 0.9 12.1 0.3 0.3 2.5 14.9 0.0 0.1 10.3 0.6 0.3 6.5 22.7 0.1 0.0 0.0 0.0 0.0 178.4 0.4 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 859.6 0.0 0.2 1.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.3 0.0 0.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.2 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 3.2 0.5 0.0 0.0 11.5 0.6 19.3 0.0 1.4 0.3 0.3 0.8 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 37.0 2.8 3.7 1.0 0.0 0.0 0.1 0.2 0.2 32.0 0.0 32.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 1.3 0.0 0.0 10.7 75.3 0.9 0.7 10.6 0.0 0.1 1.6 0.0 0.0 0.1 0.2 0.0 0.7 0.0 0.3 0.0 0.0 0.7 0.4 6.6 2.4 4.2 16.8 1.6 0.0 7.1 0.5 1.0 0.0 0.2 0.3 COPA HEP-COP ENSG00000122218 "COPI coat complex subunit alpha" P53621 1 160288594-160343273 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028024 Supported Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA NA 150000 "Cluster 18: Basophils - Vesicular transport" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA028024: AB_10603787" "unprognostic (1.59e-2)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.77e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.42e-2)" "unprognostic (3.14e-1)" "unprognostic (2.21e-1)" "unprognostic (5.03e-2)" "unprognostic (3.10e-1)" "unprognostic (2.05e-2)" "unprognostic (8.70e-2)" "unprognostic (2.03e-1)" "unprognostic (4.94e-2)" "unprognostic (1.39e-1)" 47.7 43.1 46.6 38.5 48.9 30.0 42.0 57.2 57.1 52.9 67.4 42.3 53.7 46.7 55.1 38.3 41.2 38.6 55.1 48.6 53.7 48.6 55.0 47.0 36.1 57.9 51.0 46.9 49.9 51.8 59.8 48.3 60.0 43.5 47.9 26.2 57.6 39.4 59.1 40.0 49.0 50.0 53.9 42.7 43.5 24.4 51.1 37.6 60.1 38.2 38.9 41.3 37.9 66.4 91.0 68.5 70.1 66.9 164.9 154.7 78.6 116.5 144.3 103.1 138.7 72.0 60.5 64.4 73.3 194.0 57.7 86.0 92.0 81.3 126.5 68.6 64.3 76.8 95.2 79.0 115.1 94.1 74.5 134.8 49.1 140.0 128.9 126.3 126.4 64.4 71.9 69.7 124.4 43.6 49.3 53.3 80.1 97.3 79.0 49.2 89.2 118.9 94.3 94.7 62.1 84.3 157.3 109.2 148.0 115.0 140.4 133.9 162.8 84.3 54.1 108.2 80.2 106.8 76.3 106.6 104.2 51.3 122.8 48.1 39.0 25.4 18.6 36.7 25.5 17.8 16.7 21.3 40.4 14.2 14.3 17.9 10.9 26.7 36.2 17.8 22.9 35.5 46.6 48.9 57.2 57.1 48.6 53.7 57.9 51.0 60.0 53.9 51.1 66.4 53.6 76.9 54.7 44.7 66.4 28.2 35.5 41.6 29.6 52.4 53.0 41.3 51.8 42.9 49.7 40.5 81.3 41.0 83.2 66.8 13.7 49.9 14.7 50.7 68.1 50.4 55.3 37.0 77.6 49.6 63.3 66.2 65.2 64.3 45.6 63.0 52.8 71.1 51.2 45.4 73.8 83.8 30.5 93.7 58.0 6.4 71.1 84.3 26.6 67.5 75.0 41.0 38.1 65.9 178.9 55.5 48.1 56.8 115.9 52.9 98.9 41.4 66.2 53.7 39.5 57.6 52.4 37.6 25.7 35.8 31.8 69.2 58.3 58.1 66.6 61.2 CORT MGC32686 ENSG00000241563 Cortistatin O00230 1 10450031-10451998 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 12.9" "Cell type enhanced" "Detected in some" "Adipocytes: 2.3;Early spermatids: 4.9;Late spermatids: 5.1;Spermatocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted in brain" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.25e-2)" "unprognostic (1.79e-2)" "unprognostic (1.65e-1)" "unprognostic (3.70e-3)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.94e-3)" "unprognostic (7.08e-7)" "unprognostic (2.01e-1)" "unprognostic (9.01e-4)" "unprognostic (1.62e-1)" "unprognostic (1.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.14e-4)" 0.5 0.5 5.4 0.1 12.9 0.3 0.4 2.3 6.2 0.7 1.8 0.8 0.8 0.4 0.3 0.4 0.5 0.3 0.4 4.8 3.4 1.4 1.0 0.4 0.1 1.7 1.8 0.6 0.5 0.2 1.8 0.9 1.6 0.9 0.2 1.0 0.4 0.1 0.2 0.4 0.8 0.1 1.6 0.4 0.6 1.9 4.1 0.2 0.8 0.1 0.0 0.4 0.4 3.7 0.7 1.7 0.5 0.7 0.2 0.0 0.4 0.6 0.1 0.1 0.1 1.4 0.2 0.6 0.4 0.0 0.2 0.5 0.0 0.0 0.0 1.2 1.3 0.8 1.5 1.5 0.0 0.9 0.4 0.1 0.2 0.2 0.1 0.2 0.0 0.6 0.6 0.4 0.0 1.5 0.2 1.5 0.1 0.0 2.2 0.5 0.9 0.2 0.1 0.5 0.6 0.4 0.3 0.5 0.5 0.3 0.3 0.0 0.6 0.0 1.0 0.9 0.2 0.3 1.5 0.5 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.4 12.9 2.3 6.2 4.8 3.4 1.7 1.8 1.6 1.6 4.1 3.7 2.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 4.9 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.1 1.8 0.4 0.3 0.3 0.0 0.0 0.0 0.1 0.2 CP ENSG00000047457 Ceruloplasmin P00450 3 149162410-149221829 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 1871.4" "Cell type enhanced" "Detected in many" "Club cells: 558.1;Glandular and luminal cells: 406.0;Hepatocytes: 1687.2;Muller glia cells: 720.5;Respiratory ciliated cells: 318.4" "Cancer enhanced" "Detected in many" "liver cancer: 98.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "EFO-21: 318.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001834, CAB008591" Supported "Secreted to blood" NA NA 160000000000 440000000000 "Cluster 62: Liver - Hemostasis" "Cluster 38: EFO-21 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB008591: AB_1613734, HPA001834: AB_1078502" "unprognostic (3.58e-1)" "unprognostic (4.24e-1)" "unprognostic (9.61e-2)" "unprognostic (1.80e-2)" "unprognostic (4.14e-2)" "unprognostic (1.02e-2)" "unprognostic (1.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "unprognostic (6.03e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (1.14e-7)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (2.70e-1)" 13.0 2.3 17.9 2.2 18.1 0.9 20.8 18.7 29.8 70.2 129.2 13.0 9.8 14.8 0.0 5.6 8.3 1.1 39.2 17.5 33.0 9.5 1871.4 13.4 18.9 28.1 20.3 0.8 6.5 3.9 28.6 3.4 24.9 7.9 16.4 246.5 39.9 0.9 2.6 13.0 20.8 2.4 19.2 23.1 3.0 1.5 20.1 0.5 16.1 8.3 20.0 23.9 2.3 29.0 0.2 18.8 15.6 0.0 3.3 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 318.8 0.0 29.4 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.4 32.7 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 2.5 5.4 0.0 0.0 0.0 0.4 6.7 16.2 0.0 0.2 0.3 1.0 0.1 0.4 0.0 0.4 0.0 0.2 1.7 0.2 0.2 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.1 18.7 29.8 17.5 33.0 28.1 20.3 24.9 19.2 20.1 29.0 2.3 19.2 76.6 3.3 10.6 3.3 8.3 28.6 0.6 6.9 14.0 0.6 0.6 65.8 558.1 9.2 6.2 0.1 0.3 0.1 0.0 83.4 0.9 190.5 51.0 12.6 0.0 34.7 1.5 21.4 0.2 16.3 0.0 406.0 2.5 0.1 34.6 1687.2 0.6 5.0 1.4 0.2 8.2 44.6 6.9 1.2 0.3 4.0 0.0 6.5 1.6 720.5 1.0 0.5 2.0 69.3 0.0 0.4 0.3 19.5 0.0 0.3 318.4 24.8 0.0 0.8 15.3 0.0 0.1 0.8 2.6 0.3 4.9 0.1 0.1 79.0 CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2326 "pancreas: 237498.3" "Cell type enriched" "Detected in some" 19 "Exocrine glandular cells: 10133.0" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AN3-CA: 11.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" NA NA 110000000 "Cluster 25: Pancreas - Digestion" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "CAB025197: , HPA021836: AB_1846005, HPA052215: AB_2681764" "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" 27.9 4.8 0.2 5.6 0.2 4.7 13.6 0.1 0.2 11.9 1.2 4.5 33.6 5.0 0.1 6.9 3.7 0.2 43.5 0.2 0.3 4.6 12.9 3.3 8.7 0.1 0.1 102.1 237498.3 0.0 5.0 18.4 0.1 6.9 0.0 0.2 39.5 0.1 4.7 6.6 20.8 0.4 0.2 7.7 21.3 5.4 0.2 0.1 3.0 0.4 0.0 2.8 4.0 0.4 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 1.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.2 0.3 0.1 0.1 0.1 0.2 0.2 0.4 0.1 3.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.9 12.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 10133.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.9 1.2 0.0 1.0 44.5 2.1 0.0 0.0 0.0 527.2 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.1 0.0 16.2 2.7 0.9 5.5 0.0 0.0 1.6 0.0 2.5 0.0 0.1 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266863-130289798 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 416 "pancreas: 45360.2" "Cell type enriched" "Detected in some" 10 "Exocrine glandular cells: 4973.8" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.2;CACO-2: 3.8;RH-30: 3.0;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" NA NA 1500000 "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 5.5 1.0 0.3 0.7 0.8 0.4 2.6 1.0 0.9 1.9 0.2 1.3 17.4 0.8 0.1 1.5 0.7 0.0 8.4 0.3 0.6 0.9 2.6 0.7 1.4 2.8 1.3 19.7 45360.2 0.0 1.4 3.2 2.5 1.5 0.4 0.8 7.8 0.0 0.8 1.1 30.6 0.0 1.2 1.2 108.9 2.2 1.1 0.1 0.6 0.0 0.0 0.5 0.8 3.1 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.8 0.0 0.0 0.5 0.0 0.3 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 3.0 0.0 0.0 0.3 1.6 0.0 0.1 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.6 0.4 0.3 0.0 0.4 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 1.0 0.9 0.3 0.6 2.8 1.3 2.5 1.2 1.1 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.6 1.9 8.1 4.3 0.0 0.0 0.9 0.0 0.0 0.1 4973.8 0.0 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 10.5 0.3 0.5 0.0 0.0 13.9 4.6 0.0 0.5 1.0 471.3 52.9 0.0 0.0 0.0 9.9 0.0 0.0 0.3 0.0 0.0 1.3 0.4 2.0 0.0 0.1 0.3 0.0 0.2 1.5 0.2 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865296-148897203 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 112.0;lung: 86.3" "Cell type enriched" "Detected in some" 26 "granulocytes: 4422.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 1534 "basophil: 1115.4" "Lineage enriched" "Detected in single" 5518 "granulocytes: 1115.4" "Cell line enriched" "Detected in some" 45 "HEL: 303.3" "Not detected" "Not detected" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 18.2 2.6 0.0 19.9 0.4 25.7 20.9 0.0 0.0 59.4 0.3 39.2 27.3 26.1 19.3 41.1 6.6 112.0 6.2 0.0 0.0 3.3 2.7 86.3 11.2 0.0 0.0 0.9 21.0 2.8 0.9 1.7 0.0 18.5 56.6 0.0 12.1 15.1 1.6 17.7 45.9 25.7 0.0 1.1 45.3 3.8 0.0 14.9 0.9 10.2 15.1 54.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 303.3 0.0 0.0 0.2 0.2 6.7 0.2 0.0 0.1 0.3 0.5 3.8 0.0 0.1 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1115.4 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.1 163.9 0.0 0.5 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 16.0 0.0 1.6 0.0 3.5 0.5 0.0 4422.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 5.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 6.7 0.3 0.0 0.0 8.7 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.3 0.0 41.7 0.0 0.0 0.3 CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.6;skin 1: 57.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.7;Basal respiratory cells: 23.7;Exocrine glandular cells: 54.1;Fibroblasts: 11.5;Suprabasal keratinocytes: 31.0" "Cancer enhanced" "Detected in many" "cervical cancer: 10.0;head and neck cancer: 9.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 140.1;hTERT-RPE1: 261.0;LHCN-M2: 284.2;U-2 OS: 151.0;U-87 MG: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021030 Approved Nucleoplasm,Centrosome,Cytosol "Secreted in other tissues" NA Yes 390000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Centrosome, Cytosol" "HPA021030: AB_1846010" "unprognostic (7.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.59e-3)" "unprognostic (3.63e-3)" "unprognostic (2.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.78e-2)" "unprognostic (4.36e-3)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (2.37e-3)" "unprognostic (6.49e-2)" "unprognostic (6.21e-10)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (1.31e-4)" 5.0 4.4 0.4 0.4 0.4 0.1 3.5 0.5 1.7 15.3 0.5 0.0 0.0 0.2 0.3 21.6 0.4 0.1 1.1 0.6 2.1 0.6 0.1 0.4 0.2 1.1 0.7 0.1 12.7 0.0 0.5 2.0 1.1 0.2 0.0 0.2 6.7 0.0 0.3 57.1 0.2 0.8 0.6 3.3 0.4 0.3 1.2 0.8 0.0 0.0 0.9 0.0 12.6 1.1 95.3 5.0 0.3 0.3 0.7 1.5 0.1 74.6 140.1 74.9 18.5 0.7 8.1 0.1 14.3 31.9 75.2 5.5 0.0 41.3 76.7 0.4 0.3 0.0 33.3 2.1 1.8 0.3 0.2 1.0 65.2 6.7 9.4 261.0 0.3 0.1 0.0 0.2 284.2 0.2 0.0 0.0 0.8 0.4 11.1 0.3 75.4 0.1 34.5 4.0 0.2 0.0 49.9 23.3 0.5 28.0 0.5 0.4 57.3 18.1 151.0 6.2 7.4 0.2 0.2 0.1 272.7 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.5 1.7 0.6 2.1 1.1 0.7 1.1 0.6 1.2 1.1 0.0 3.2 0.5 0.0 0.0 17.7 0.5 23.7 0.6 0.0 4.2 2.8 0.3 0.0 8.5 0.0 0.0 5.6 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.3 0.0 0.0 0.4 54.1 1.2 11.5 0.0 2.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.2 0.0 0.3 3.6 1.0 0.6 0.0 0.0 0.0 0.5 7.9 0.0 0.0 0.0 0.9 0.0 0.1 2.9 0.0 0.0 1.3 0.4 0.1 0.7 10.0 31.0 9.4 0.1 0.0 0.0 1.6 CPA5 ENSG00000158525 "Carboxypeptidase A5" Q8WXQ8 7 130344816-130368730 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 33.6" "Group enriched" "Detected in some" 23 "Early spermatids: 76.1;Late spermatids: 144.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 16.8;naive CD8 T-cell: 42.5;T-reg: 56.4" "Lineage enriched" "Detected in single" 102 "T-cells: 56.4" "Cell line enhanced" "Detected in some" "RH-30: 7.3;RT4: 3.4;U-266/84: 6.0" "Not detected" "Not detected" HPA020322 Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 83: Testis - Spermatogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA020322: AB_10960562" "unprognostic (2.44e-1)" "unprognostic (3.76e-1)" "unprognostic (1.50e-1)" "unprognostic (5.94e-2)" "unprognostic (4.96e-2)" "unprognostic (7.10e-3)" "unprognostic (1.64e-2)" "unprognostic (1.41e-2)" "unprognostic (3.26e-1)" "unprognostic (5.02e-2)" "unprognostic (5.83e-4)" "unprognostic (1.43e-1)" "unprognostic (8.88e-13)" "unprognostic (5.16e-2)" "unprognostic (1.32e-1)" "unprognostic (8.81e-2)" "unprognostic (3.08e-2)" 0.3 0.2 0.3 0.1 0.2 0.2 0.1 0.2 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 1.9 0.3 0.4 0.0 0.5 0.0 1.2 0.6 0.4 0.1 0.0 0.0 0.0 0.0 0.2 1.0 0.7 0.0 0.2 1.8 0.0 33.6 0.5 2.2 0.3 0.0 0.9 0.6 0.0 0.4 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.3 2.1 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.0 0.0 1.2 0.5 0.5 0.8 0.3 0.0 0.0 0.0 0.7 0.0 0.9 0.9 0.0 0.6 0.0 1.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 7.3 0.2 1.0 3.4 0.9 0.1 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 6.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.6 0.0 16.8 8.6 0.0 0.0 4.2 42.5 0.0 0.0 0.0 0.0 56.4 5.8 0.3 0.2 0.2 1.0 0.4 0.5 0.3 0.4 0.4 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.0 0.0 1.8 0.0 3.1 0.0 0.0 0.0 0.1 76.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 144.1 0.9 0.1 0.0 0.0 0.9 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 3.8 2.6 0.0 0.0 4.7 4.0 0.0 0.0 0.1 CPA6 CPAH ENSG00000165078 "Carboxypeptidase A6" Q8N4T0 8 67422038-67746378 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.3;prostate: 2.7;retina: 2.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 31.7;Early spermatids: 21.7;Microglial cells: 12.2;Muller glia cells: 22.5;Pancreatic endocrine cells: 21.5;Paneth cells: 12.8;Prostatic glandular cells: 11.3;Urothelial cells: 36.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.5;EFO-21: 1.5;Hep G2: 3.4;OE19: 1.5" "Region enriched" "Detected in some" 9 "olfactory bulb: 12.6" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.85e-2)" "unprognostic (1.95e-1)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (2.58e-1)" "unprognostic (2.24e-1)" "unprognostic (2.08e-1)" "unprognostic (2.88e-1)" "unprognostic (9.35e-2)" "unprognostic (1.65e-1)" "unprognostic (5.23e-2)" "unprognostic (6.99e-2)" "unprognostic (3.57e-4)" "unprognostic (9.61e-5)" "unprognostic (1.75e-1)" "unprognostic (9.09e-2)" "unprognostic (1.41e-2)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.3 2.2 0.0 0.2 0.0 0.0 0.2 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 31.7 0.0 5.7 0.2 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 21.7 0.1 0.0 0.1 2.4 0.0 1.6 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.7 1.3 2.2 0.0 0.0 0.0 3.2 1.8 0.2 0.0 12.2 0.1 22.5 0.0 3.0 1.3 21.5 12.8 0.0 0.0 11.3 0.0 0.0 0.0 1.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.6 0.0 5.7 36.6 CPAMD8 "K-CAP, KIAA1283, VIP" ENSG00000160111 "C3 and PZP like alpha-2-macroglobulin domain containing 8" Q8IZJ3 19 16892951-17026815 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.7;prostate: 34.1;seminal vesicle: 36.1" "Cell type enhanced" "Detected in many" "Adipocytes: 19.5;Alveolar cells type 1: 22.4;Alveolar cells type 2: 29.8;Collecting duct cells: 27.6;Leydig cells: 31.4;Prostatic glandular cells: 19.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 19.5;EFO-21: 12.6;T-47d: 34.4" "Region enriched" "Detected in single" 8 "spinal cord: 5.6" "HPA031327, HPA031328, HPA031329, HPA031330" Uncertain Uncertain "Focal adhesion sites" "Secreted to blood" NA NA 2700000 "Cluster 21: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 43: Cardiomyocytes - Nuclear processes" "Focal adhesion sites" "HPA031327: AB_2673829, HPA031328: AB_2673830, HPA031329: , HPA031330: AB_10603788" "unprognostic (4.71e-3)" "unprognostic (1.07e-2)" "unprognostic (4.20e-2)" "unprognostic (2.76e-2)" "unprognostic (4.32e-2)" "unprognostic (4.06e-3)" "unprognostic (7.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-2)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" "unprognostic (8.69e-2)" "unprognostic (1.01e-3)" "unprognostic (2.08e-1)" "unprognostic (8.45e-2)" "unprognostic (1.80e-2)" 6.8 2.5 7.9 0.5 15.6 0.5 6.2 35.7 3.7 7.7 4.3 1.0 0.3 2.2 10.5 0.5 1.8 0.3 23.8 2.4 7.2 19.0 0.8 15.0 0.2 23.5 26.2 1.6 0.4 3.2 4.1 4.2 21.3 34.1 0.1 0.5 2.8 36.1 2.8 1.6 1.2 0.4 25.5 1.7 0.8 2.3 17.8 1.2 21.0 2.9 0.3 1.6 3.1 32.0 0.0 0.0 0.8 0.0 0.0 0.0 19.5 0.0 0.1 0.0 0.0 0.0 0.0 0.5 12.6 0.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 1.1 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 3.2 0.7 0.0 0.0 1.9 0.0 0.1 0.5 2.8 0.1 0.0 0.0 0.6 0.0 0.1 34.4 0.2 0.0 0.1 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 15.6 35.7 3.7 2.4 7.2 23.5 26.2 21.3 25.5 17.8 32.0 19.5 22.4 29.8 3.6 0.5 0.9 10.1 5.8 1.2 2.3 7.5 9.0 6.1 1.5 10.7 27.6 0.0 9.1 0.4 1.0 0.0 0.9 1.8 3.1 3.2 15.1 0.0 0.0 0.8 0.0 6.1 2.8 2.0 6.1 2.5 1.8 11.7 0.3 3.1 0.0 0.8 0.7 0.0 6.3 1.4 4.3 31.4 5.8 0.0 1.9 3.3 0.1 2.1 1.5 1.0 1.2 1.4 6.4 3.4 19.3 0.0 0.1 4.7 0.1 0.0 1.6 2.1 6.2 1.2 0.4 0.6 6.0 0.4 1.7 0.2 6.0 CPB1 ENSG00000153002 "Carboxypeptidase B1" P15086 3 148791102-148860187 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1970 "pancreas: 226925.8" "Cell type enriched" "Detected in some" 12 "Exocrine glandular cells: 7306.0" "Group enriched" "Detected in some" 312 "breast cancer: 293.8;pancreatic cancer: 641.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 1.0;U-2 OS: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026158, HPA038069, HPA046340" Enhanced "Secreted to digestive system" NA NA 88000000 "Cluster 17: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB026158: , HPA038069: AB_2675816, HPA046340: AB_2679628" "unprognostic (6.90e-2)" "unprognostic (3.79e-2)" "unprognostic (3.34e-2)" "unprognostic (2.64e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (6.26e-4)" "unprognostic (1.90e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (7.59e-2)" "unprognostic (4.51e-2)" "unprognostic (5.50e-8)" "unprognostic (3.08e-1)" "unprognostic (1.60e-1)" "unprognostic (4.93e-2)" 15.7 83.0 0.4 5.1 1.7 2.5 78.3 0.6 1.4 6.0 0.1 2.6 31.2 4.7 0.3 3.5 1.8 0.1 40.8 0.6 0.8 2.0 7.1 1.7 8.1 1.0 1.2 115.1 226925.8 0.0 2.1 13.7 1.1 4.7 4.5 0.0 36.3 0.0 2.2 2.8 17.2 0.0 0.4 19.2 28.3 2.9 1.2 0.1 1.6 0.0 0.0 1.4 2.0 3.3 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.5 0.0 0.9 0.2 0.0 0.0 0.0 4.0 0.3 0.5 1.3 0.4 0.9 0.4 0.5 1.1 0.1 0.7 0.3 1.4 1.9 1.4 0.5 0.5 0.3 0.4 0.4 1.7 0.6 1.4 0.6 0.8 1.0 1.2 1.1 0.4 1.2 3.3 2.2 0.0 0.0 1.0 0.0 0.6 0.5 0.0 0.0 0.0 8.7 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 11.6 11.2 0.0 0.1 1.1 164.9 1.3 0.3 7306.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.2 0.0 0.0 1.0 2.5 0.6 1.5 0.0 0.0 18.1 0.0 0.0 0.0 29.8 590.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 4.2 2.5 0.0 1.1 0.1 0.3 0.3 0.3 1.1 0.2 0.2 CPB2 "CPU, PCPB, TAFI" ENSG00000080618 "Carboxypeptidase B2" Q96IY4 13 46053186-46105033 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "liver: 1484.1" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1332.7" "Cancer enriched" "Detected in some" 112 "liver cancer: 268.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 86 "Hep G2: 173.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA004146 Approved "Secreted to blood" NA NA 8500000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA004146: AB_1078397" "unprognostic (3.44e-2)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.89e-2)" "unprognostic (7.69e-2)" "unprognostic (1.17e-2)" "prognostic favorable (2.06e-4)" "unprognostic (1.89e-1)" "unprognostic (2.74e-1)" "unprognostic (2.48e-1)" "unprognostic (3.17e-2)" "unprognostic (4.83e-2)" "unprognostic (3.20e-3)" "unprognostic (1.34e-1)" "unprognostic (7.10e-2)" "unprognostic (3.34e-2)" "unprognostic (9.61e-2)" 0.1 0.0 0.5 0.1 3.1 0.7 0.1 0.6 1.8 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 4.8 0.0 0.5 1.4 0.4 1484.1 17.6 0.1 1.7 2.0 0.0 0.5 0.0 0.0 0.0 2.5 0.1 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.0 0.3 0.4 0.1 0.2 2.2 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.6 0.3 173.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.1 0.0 2.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.5 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 3.1 0.6 1.8 0.5 1.4 1.7 2.0 2.5 0.3 2.2 5.1 0.0 3.2 27.0 3.9 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 190.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 1.0 0.0 10.7 4.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 15.7 1332.7 0.1 0.0 5.3 0.0 0.0 22.7 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 13.0 36.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081869 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 81.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 37.2" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "SK-MEL-30: 141.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 81.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 141.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 37.2 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.6 4.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 CPN2 ACBP ENSG00000178772 "Carboxypeptidase N subunit 2" P22792 3 194339768-194351328 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 218.6" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 171.8" "Cancer enriched" "Detected in some" 32 "liver cancer: 72.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "Hep G2: 61.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA004732 Uncertain "Secreted to blood" NA NA 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA004732: AB_1078561" "unprognostic (4.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.42e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.27e-1)" "unprognostic (8.65e-2)" "unprognostic (8.56e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.91e-2)" "unprognostic (2.40e-1)" "unprognostic (6.90e-5)" "unprognostic (8.42e-2)" 0.4 3.0 0.7 0.4 0.6 1.5 0.2 0.6 1.1 0.2 0.0 0.2 0.0 0.4 0.4 0.1 0.2 0.4 1.0 0.7 0.8 14.7 218.6 0.2 0.3 0.2 0.2 0.3 0.1 0.1 0.0 0.4 0.2 0.2 0.2 1.1 0.2 0.1 0.1 0.6 0.2 0.2 0.0 1.2 0.4 0.7 0.4 0.1 0.3 0.0 0.2 0.1 0.0 1.1 0.2 0.1 0.3 0.3 0.1 0.8 0.2 0.3 0.1 0.0 0.0 0.4 0.2 0.2 0.3 0.8 0.4 0.5 0.1 0.0 0.2 0.1 0.2 0.3 0.6 61.8 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.3 0.5 0.6 0.0 0.3 0.2 0.3 0.3 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.3 0.2 0.3 0.2 0.4 0.3 0.2 1.4 1.6 0.2 2.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.6 1.1 0.7 0.8 0.2 0.2 0.2 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 171.8 0.2 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 CPXM1 "CPX-1, CPX1, CPXM" ENSG00000088882 "Carboxypeptidase X, M14 family member 1" Q96SM3 20 2794074-2800627 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 162.7;Fibroblasts: 60.1;Theca cells: 28.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebral cortex: 6.9" "Immune cell enhanced" "Detected in single" "NK-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 161.7;HSkMC: 85.7;NB-4: 148.1;REH: 150.8;SH-SY5Y: 108.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 8.7" "Secreted in other tissues" NA NA 490000 "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (7.48e-2)" "unprognostic (3.61e-1)" "unprognostic (6.70e-2)" "unprognostic (1.47e-2)" "unprognostic (3.41e-1)" "unprognostic (5.24e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (9.32e-2)" "unprognostic (7.02e-2)" "unprognostic (3.23e-2)" "prognostic unfavorable (4.62e-10)" "unprognostic (1.30e-1)" "unprognostic (1.49e-1)" "unprognostic (5.55e-3)" "unprognostic (1.27e-2)" 59.0 4.8 0.9 9.7 1.2 19.0 31.2 0.7 6.9 72.4 2.5 4.1 1.4 76.8 8.4 4.2 27.1 86.0 4.5 0.9 0.9 6.5 0.3 5.4 6.5 0.9 0.7 41.9 3.1 3.8 5.3 51.5 1.1 7.1 1.5 0.0 4.8 2.3 1.2 12.7 3.3 38.8 1.1 0.9 2.2 3.6 1.4 9.6 24.5 0.0 2.8 55.5 29.4 1.0 0.0 0.0 161.7 0.0 0.0 4.9 0.2 0.4 0.7 2.0 0.6 0.0 0.0 0.0 0.5 0.3 0.1 0.0 12.1 0.0 0.5 0.7 8.5 22.1 0.0 0.0 2.2 0.1 3.2 85.7 0.0 7.7 0.0 0.0 0.0 31.1 9.3 0.0 0.1 0.1 0.6 148.1 34.5 0.0 0.0 150.8 0.0 4.2 0.0 0.0 0.2 108.2 0.0 0.2 0.0 25.8 0.0 1.9 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.9 1.2 0.7 6.9 0.9 0.9 0.9 0.7 1.1 1.1 1.4 1.0 3.9 0.0 0.5 0.0 0.3 2.7 5.8 0.7 4.0 0.0 1.1 3.8 0.7 0.0 0.8 3.7 0.0 2.9 1.7 0.5 0.0 3.0 2.3 5.8 162.7 3.1 0.0 7.6 0.0 0.0 3.3 60.1 0.0 4.2 2.5 17.7 0.7 0.0 6.5 0.0 0.0 0.0 0.0 0.0 2.6 2.8 17.4 0.9 1.8 0.0 0.7 0.0 0.0 0.5 0.0 0.3 0.0 0.7 0.5 2.5 0.0 0.1 3.1 0.0 0.0 0.4 10.2 0.0 1.5 0.1 2.0 3.3 1.4 28.2 0.6 0.8 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 144.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.5;Fibroblasts: 8.5;Microglial cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 73.6;BJ: 39.7;BJ hTERT+: 51.7;hTERT-RPE1: 30.6;RH-30: 57.6;U-2197: 46.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" 11.1 1.8 0.3 2.7 1.0 0.0 11.8 0.5 2.9 33.3 2.3 4.6 0.8 14.6 9.1 7.4 19.9 30.7 2.8 0.8 0.4 2.0 1.4 7.1 2.8 0.7 0.5 144.3 3.2 1.8 5.2 42.1 0.8 5.9 1.8 0.1 1.5 24.2 0.2 13.8 2.6 8.4 1.2 1.4 3.3 3.1 0.3 1.5 7.8 0.0 1.0 23.0 25.1 0.9 26.1 0.4 0.0 1.6 5.0 0.5 73.6 39.7 51.7 14.5 5.8 1.7 0.7 0.0 3.7 21.3 0.3 0.0 0.0 0.0 5.4 0.0 2.9 0.0 0.3 0.7 4.4 0.0 0.0 9.2 0.0 0.0 0.0 30.6 0.0 0.0 1.2 0.0 0.9 6.1 0.0 0.1 9.2 0.2 22.0 0.1 57.6 0.0 0.0 1.1 0.1 0.1 1.4 0.5 0.1 8.3 0.3 0.0 0.0 2.0 2.6 46.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.5 2.9 0.8 0.4 0.7 0.5 0.8 1.2 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.0 0.6 8.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 CR1L ENSG00000197721 "Complement C3b/C4b receptor 1 like" Q2VPA4 1 207645113-207738416 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "bone marrow: 1.5" "Cell type enriched" "Detected in some" 18 "Erythroid cells: 128.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HEL: 1.3;HMC-1: 2.9;K-562: 1.6" HPA049348 Approved "Secreted in other tissues" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "HPA049348: AB_2680723" "unprognostic (2.35e-2)" "unprognostic (8.27e-2)" "unprognostic (1.99e-1)" "unprognostic (8.89e-2)" "unprognostic (1.31e-2)" "unprognostic (5.50e-2)" "unprognostic (2.01e-1)" "unprognostic (7.45e-2)" "unprognostic (5.27e-2)" "unprognostic (8.21e-3)" "unprognostic (7.94e-2)" "unprognostic (3.02e-1)" "unprognostic (6.33e-2)" "unprognostic (2.02e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (9.68e-2)" 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.5 0.5 0.0 0.3 1.8 0.0 0.1 0.0 0.0 5.9 0.4 0.2 6.9 0.2 1.8 0.0 128.6 0.4 0.0 0.1 0.2 0.0 1.0 0.0 0.0 3.6 0.2 1.2 0.0 0.4 0.0 2.0 0.3 0.3 0.4 0.0 0.5 0.0 1.0 1.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.2 3.3 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.3 0.3 0.1 0.1 0.0 0.2 CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.3;retina: 74.7" "Cell type enhanced" "Detected in some" "Astrocytes: 469.5;Cone photoreceptor cells: 164.7;Inhibitory neurons: 130.1;Muller glia cells: 79.7;Oligodendrocyte precursor cells: 280.0;Oligodendrocytes: 105.6;Rod photoreceptor cells: 149.3" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 8 "HeLa: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" 0.1 0.1 15.7 0.0 17.6 0.4 0.1 19.8 20.5 0.0 9.6 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.2 15.8 14.2 0.1 0.0 0.1 0.1 18.7 18.4 0.7 0.4 0.0 2.2 0.0 17.5 0.0 0.0 74.7 0.0 0.0 0.7 0.0 0.0 0.0 18.9 0.0 0.2 2.9 16.1 0.0 0.2 0.5 0.0 0.0 0.0 21.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 15.7 17.6 19.8 20.5 15.8 14.2 18.7 18.4 17.5 18.9 16.1 21.3 0.0 0.0 0.0 469.5 0.0 0.3 0.2 0.3 0.0 15.0 0.2 0.1 1.1 0.0 0.2 0.0 164.7 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.7 0.0 11.6 53.2 0.0 0.0 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 1.7 130.1 0.0 2.0 0.0 0.5 1.6 1.8 0.0 0.0 24.4 0.0 79.7 0.0 280.0 105.6 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.9 149.3 0.0 0.2 0.1 1.8 0.3 0.0 0.3 0.0 0.1 0.2 0.0 0.0 CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 545.7;Kupffer cells: 559.7;monocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Cell line enhanced" "Detected in all" "RPMI-8226: 1237.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" 130.5 127.7 37.5 79.0 41.1 125.9 109.7 39.0 45.9 76.8 47.8 77.1 60.3 61.8 109.7 91.7 70.9 128.2 82.2 36.5 40.4 132.1 295.2 99.1 98.9 46.0 39.1 84.2 70.7 75.4 64.8 110.8 44.4 62.9 82.7 80.0 104.5 74.6 71.4 109.8 63.0 77.9 45.7 136.9 61.4 50.1 49.3 35.5 125.8 78.2 63.5 116.3 63.3 61.2 93.5 41.5 21.1 43.5 325.8 89.8 53.0 39.2 17.8 30.7 39.8 67.8 104.4 101.7 112.2 43.6 57.2 143.3 24.3 84.9 20.9 140.3 82.3 41.5 31.1 37.9 111.5 93.6 295.2 94.5 250.5 35.6 38.7 42.7 10.3 35.9 218.5 405.0 42.6 39.2 19.6 95.9 22.8 214.0 63.9 32.5 58.8 1237.2 54.7 64.9 14.0 25.7 98.1 132.8 112.8 70.1 175.5 252.7 19.1 8.0 39.6 126.2 25.9 79.4 168.4 67.7 131.6 96.0 16.3 55.4 128.4 75.7 5.1 75.7 8.0 4.3 7.5 6.5 89.9 2.1 16.6 8.8 43.7 11.0 72.3 6.2 3.9 57.6 37.5 41.1 39.0 45.9 36.5 40.4 46.0 39.1 44.4 45.7 49.3 61.2 44.7 35.3 90.1 5.9 15.3 44.1 49.1 23.1 56.9 17.9 61.7 63.8 55.7 65.8 32.2 55.2 89.6 91.5 18.3 15.6 23.5 36.0 27.6 33.9 19.3 34.2 29.3 124.8 24.7 39.7 41.7 78.4 21.9 64.1 29.9 62.0 48.2 90.3 545.7 15.2 22.1 44.5 14.2 559.7 57.6 27.4 43.5 213.8 24.9 26.2 322.8 30.5 6.2 10.1 14.6 21.0 31.5 28.6 27.8 34.0 46.3 60.6 18.5 31.5 13.1 43.2 40.8 65.5 42.0 86.3 51.1 126.7 17.3 38.9 50.4 44.0 CREG2 ENSG00000175874 "Cellular repressor of E1A stimulated genes 2" Q8IUH2 2 101345550-101387503 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "brain: 27.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 66.0;Inhibitory neurons: 27.6;Oligodendrocytes: 12.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 12 "amygdala: 8.7;basal ganglia: 17.2;cerebral cortex: 26.3;hippocampal formation: 27.8;white matter: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.5;HaCaT: 6.3;HeLa: 2.5;OE19: 7.1;PC-3: 2.4;RT4: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038224 Enhanced "Secreted in brain" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038224: AB_10673167" "unprognostic (5.09e-2)" "unprognostic (3.78e-3)" "unprognostic (4.10e-3)" "unprognostic (8.15e-3)" "unprognostic (5.63e-3)" "unprognostic (9.68e-3)" "unprognostic (4.52e-8)" "unprognostic (3.86e-4)" "unprognostic (1.39e-1)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (7.69e-2)" "unprognostic (5.41e-3)" "unprognostic (4.44e-2)" "unprognostic (2.91e-1)" "unprognostic (8.26e-3)" "unprognostic (7.77e-2)" 0.0 0.1 8.7 0.0 17.2 0.1 0.0 0.0 26.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 27.8 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.7 9.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.1 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.7 17.2 0.0 26.3 27.8 0.0 1.3 0.0 0.6 0.0 1.4 9.0 0.0 0.0 0.0 2.9 0.0 0.0 0.6 0.5 0.0 0.8 0.1 0.1 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.2 0.0 0.5 0.0 0.0 66.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 27.6 0.1 2.0 0.0 0.0 6.5 0.0 0.2 0.0 6.5 0.0 0.8 0.0 2.5 12.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.5 0.0 0.2 0.1 1.5 5.6 0.5 0.0 0.1 0.0 0.2 0.0 1.5 CRH "CRF, CRH1" ENSG00000147571 "Corticotropin releasing hormone" P06850 8 66176376-66178464 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 137.2" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 160.6" "Cancer enriched" "Detected in some" 28 "urothelial cancer: 34.5" "Region enriched" "Detected in many" 6 "medulla oblongata: 137.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "pons: 25.1" "Secreted to blood" NA NA 10000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.62e-1)" "unprognostic (9.68e-2)" "unprognostic (1.00e-1)" "unprognostic (9.55e-2)" "unprognostic (7.22e-3)" 1.5 0.2 5.6 0.0 2.2 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 9.6 0.0 0.0 0.0 0.0 137.2 9.8 0.0 1.6 0.7 0.2 6.6 16.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.8 23.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 2.2 0.0 5.4 1.3 9.6 137.2 9.8 16.9 0.2 23.0 1.5 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 31.5 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 160.6 0.0 0.0 0.0 0.1 CRHBP "CRF-BP, CRFBP" ENSG00000145708 "Corticotropin releasing hormone binding protein" P24387 5 76953045-76981158 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 166.5" "Group enriched" "Detected in some" 6 "Granulosa cells: 480.8;Hepatic stellate cells: 1319.7" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 4.4;BJ hTERT+ SV40 Large T+ RasG12V: 4.4;HBF TERT88: 7.7;hTEC/SVTERT24-B: 2.6;RPMI-8226: 2.5;U-698: 7.6;U-87 MG: 4.3;WM-115: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036234, HPA046120" Approved Supported "Secreted to blood" NA NA 69000000 "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA036234: , HPA046120: AB_10959760" "unprognostic (1.41e-1)" "unprognostic (2.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.36e-3)" "unprognostic (4.44e-5)" "unprognostic (2.16e-1)" "unprognostic (7.08e-2)" "unprognostic (4.98e-4)" "unprognostic (1.09e-1)" "unprognostic (6.63e-5)" "unprognostic (2.76e-2)" "unprognostic (4.64e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-2)" 22.2 13.7 4.1 0.7 5.6 3.2 6.2 3.2 7.5 3.7 2.2 0.4 0.6 2.6 0.9 0.2 1.8 0.8 7.4 5.8 15.8 36.5 166.5 0.5 0.9 7.0 9.1 1.3 0.1 0.6 0.1 10.2 11.9 1.1 0.4 0.1 1.1 4.1 0.9 0.5 0.7 1.5 3.7 37.2 0.3 0.8 20.1 0.5 4.1 1.3 0.6 0.9 0.8 7.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 4.4 4.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 7.6 4.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.1 5.6 3.2 7.5 5.8 15.8 7.0 9.1 11.9 3.7 20.1 7.0 134.9 0.0 0.0 1.3 8.8 0.4 0.0 0.0 0.0 0.0 0.4 1.1 0.7 17.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 45.9 0.0 39.4 0.8 0.2 0.2 0.3 0.0 0.0 0.0 480.8 1319.7 9.9 1.8 0.0 32.4 0.0 0.0 75.0 2.1 1.0 0.3 3.8 0.0 4.7 0.3 0.0 0.0 0.5 11.1 0.0 0.0 0.0 0.9 0.0 0.0 3.6 0.0 0.0 0.0 0.1 2.3 0.5 1.9 0.1 0.0 0.0 1.7 0.0 0.0 0.1 CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;choroid plexus: 21.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.0;Excitatory neurons: 8.2;Horizontal cells: 13.5;Inhibitory neurons: 4.9;Smooth muscle cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" 0.6 0.0 1.5 0.0 1.0 0.0 0.6 0.4 6.0 0.3 21.7 0.2 0.3 0.3 0.0 0.2 0.5 0.1 2.1 2.3 1.0 0.8 0.0 0.1 0.0 1.4 1.0 0.4 1.7 0.1 4.2 0.0 0.4 0.2 0.1 2.5 0.3 1.3 1.2 0.2 0.3 0.1 0.4 0.0 0.2 0.8 2.8 0.0 0.7 2.2 0.0 0.3 0.2 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.4 6.0 2.3 1.0 1.4 1.0 0.4 0.4 2.8 2.4 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 4.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRISP1 "AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP" ENSG00000124812 "Cysteine rich secretory protein 1" P54107 6 49834257-49877096 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "epididymis: 1573.9" "Group enriched" "Detected in some" 29 "Early spermatids: 45.5;Late spermatids: 71.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.0;NB-4: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028445, HPA030534" Enhanced "Secreted in male reproductive system" NA NA 35000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA028445: AB_10670428, HPA030534: AB_2732459" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1573.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 66.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.5 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 71.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CRISP2 "CRISP-2, CT36, GAPDL5, TPX1" ENSG00000124490 "Cysteine rich secretory protein 2" P16562 6 49692358-49713590 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "testis: 505.0" "Group enriched" "Detected in some" 33 "Early spermatids: 5765.5;Late spermatids: 21517.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031248 Enhanced "Secreted in male reproductive system" NA NA 820000 "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA031248: AB_10602211" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.35e-2)" "unprognostic (9.23e-3)" "unprognostic (4.05e-2)" 0.1 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 1.9 0.7 0.0 0.1 0.2 0.9 3.6 17.6 7.7 0.1 0.0 0.2 0.8 0.2 1.2 0.0 0.1 0.1 0.1 0.6 0.0 2.0 0.0 0.0 1.2 0.0 0.1 15.6 2.5 0.2 0.5 0.3 0.0 0.0 0.5 0.1 505.0 0.1 0.0 0.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5765.5 17.8 0.5 6.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21517.6 133.9 6.1 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 83.8 0.0 2.8 0.2 0.1 24.1 0.0 65.7 0.0 0.0 409.8 65.1 0.0 0.0 0.0 0.0 0.0 0.3 2.3 CRISP3 "Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28" ENSG00000096006 "Cysteine rich secretory protein 3" P54108 6 49727376-49744437 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 1203.8;salivary gland: 2310.0" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 182.2;Glandular and luminal cells: 551.5" "Group enriched" "Detected in many" 7 "breast cancer: 31.9;pancreatic cancer: 59.8;prostate cancer: 85.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "neutrophil: 2.5;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 19 "granulocytes: 2.5;monocytes: 1.2" "Group enriched" "Detected in some" 20 "HEL: 12.3;RT4: 4.1;SK-BR-3: 9.3;T-47d: 4.4" "Not detected" "Not detected" HPA054392 Supported "Secreted in other tissues" NA NA 420000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" "HPA054392: AB_2682472" "unprognostic (1.28e-2)" "unprognostic (7.01e-2)" "unprognostic (8.93e-2)" "unprognostic (5.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.22e-4)" "unprognostic (5.30e-2)" "unprognostic (6.70e-2)" "unprognostic (9.16e-2)" "unprognostic (4.34e-3)" "unprognostic (1.91e-1)" "unprognostic (1.93e-1)" 0.3 0.6 0.0 0.0 0.0 381.8 3.9 0.0 0.0 61.0 0.0 0.1 0.4 1.7 0.1 266.8 1203.8 23.1 0.8 0.0 0.0 0.1 0.9 1.3 0.0 0.0 0.0 0.5 5.5 0.0 0.5 0.6 0.0 2.9 0.0 0.0 2310.0 111.9 0.3 3.9 0.2 0.0 0.0 2.5 0.3 0.2 0.0 0.3 0.2 0.0 4.0 4.7 140.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 9.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.0 2.1 5.6 0.0 21.5 13.1 3.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 182.2 47.2 0.8 0.0 0.4 0.0 3.7 0.0 0.2 0.0 551.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 26.8 CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 29.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 36.1;Endometrial ciliated cells: 62.2;Oligodendrocyte precursor cells: 81.4" "Cancer enhanced" "Detected in many" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 134.4;SH-SY5Y: 72.0;SuSa: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" NA NA 8200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA024725: AB_1847238" "unprognostic (2.16e-1)" "unprognostic (5.88e-2)" "unprognostic (4.01e-2)" "unprognostic (3.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (5.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (7.39e-3)" "unprognostic (2.38e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" 2.7 1.3 3.9 2.5 4.0 1.5 29.4 3.4 3.1 6.3 3.4 2.7 0.7 8.6 4.9 5.0 7.4 10.0 8.8 4.3 8.0 2.1 2.1 2.3 2.8 5.8 10.4 5.7 2.4 19.3 1.2 7.8 8.3 24.6 1.6 3.1 19.3 2.6 0.5 2.3 1.2 7.0 6.3 2.0 0.9 3.8 4.1 9.4 15.1 1.2 1.1 2.5 1.1 10.7 0.0 1.7 134.4 0.0 0.0 0.0 4.5 0.0 0.0 1.6 1.9 0.8 0.0 0.0 19.0 0.0 2.2 0.1 11.3 0.1 0.0 0.1 5.2 0.2 5.1 0.0 3.0 0.0 1.0 7.2 0.3 0.1 1.0 16.6 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.2 13.9 0.0 5.0 0.0 18.5 0.2 0.0 0.0 0.8 72.0 0.0 0.1 8.0 27.5 10.4 6.4 0.0 3.8 19.6 0.2 0.5 2.4 0.9 0.0 4.6 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.9 4.0 3.4 3.1 4.3 8.0 5.8 10.4 8.3 6.3 4.1 10.7 1.0 3.2 0.0 12.7 0.0 0.8 6.1 1.4 17.6 1.6 10.3 36.1 0.4 0.0 5.4 1.8 0.0 22.7 0.3 0.0 0.0 0.0 15.3 62.2 4.9 3.2 0.0 3.0 15.7 0.0 3.8 9.2 0.0 22.4 3.8 1.8 23.6 0.1 2.0 0.0 11.1 0.0 0.0 0.9 0.0 1.5 4.1 0.4 7.2 1.9 0.0 8.8 0.0 81.4 0.9 0.0 0.0 1.5 0.0 9.4 0.0 0.2 22.5 0.9 0.0 0.4 1.5 1.3 6.0 2.5 1.0 12.0 0.4 6.3 0.0 2.3 CRISPLD2 "DKFZP434B044, LCRISP2, LGL1" ENSG00000103196 "Cysteine rich secretory protein LCCL domain containing 2" Q9H0B8 16 84819985-84920768 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 137.3;Fibroblasts: 185.5;Leydig cells: 271.5;Peritubular cells: 265.9;Skeletal myocytes: 146.2;Smooth muscle cells: 341.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 87.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 87.2" "Cell line enhanced" "Detected in many" "ASC diff: 43.7;BEWO: 69.2;HHSteC: 161.4;HSkMC: 68.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 15.6" "HPA030054, HPA030055" Approved Approved Nucleoplasm,Nucleoli "Secreted to blood" No No 219000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "HPA030054: AB_2732452, HPA030055: AB_10611821" "unprognostic (8.91e-3)" "unprognostic (3.05e-1)" "unprognostic (2.63e-2)" "unprognostic (2.02e-2)" "unprognostic (7.12e-2)" "unprognostic (2.30e-1)" "unprognostic (2.11e-2)" "unprognostic (5.58e-3)" "unprognostic (1.48e-1)" "unprognostic (5.50e-2)" "unprognostic (2.67e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (7.35e-3)" "unprognostic (3.38e-2)" "unprognostic (2.99e-3)" "unprognostic (5.15e-3)" 113.4 29.0 3.3 46.6 4.9 8.1 64.2 3.9 4.6 112.9 2.6 88.9 10.8 115.7 20.3 39.9 129.0 104.0 36.6 3.7 5.2 40.9 17.1 92.7 7.3 5.9 5.5 80.7 23.5 2.5 19.3 122.7 5.9 98.9 18.1 2.4 18.1 27.7 15.0 36.7 58.5 95.0 4.4 24.9 65.9 21.5 4.3 8.2 47.9 12.2 3.7 119.9 69.8 5.7 0.9 2.2 0.6 6.0 43.7 16.2 69.2 34.5 30.4 27.2 19.1 4.7 2.9 0.1 3.0 30.5 8.0 1.0 0.1 0.1 27.3 0.0 0.2 0.5 0.9 0.1 161.4 0.0 0.3 68.0 0.1 8.0 0.1 9.0 0.2 0.0 0.3 0.3 3.1 1.4 0.3 1.7 2.0 4.6 2.0 0.1 0.3 0.4 0.2 5.5 6.7 0.5 8.1 3.5 0.7 9.4 13.7 0.9 3.8 0.4 1.8 28.3 1.0 0.4 0.1 5.8 0.2 0.5 4.1 14.8 20.2 0.7 0.0 1.2 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.0 87.2 0.0 0.0 0.1 0.0 4.2 3.3 4.9 3.9 4.6 3.7 5.2 5.9 5.5 5.9 4.4 4.3 5.7 5.9 3.2 2.3 0.7 0.7 46.1 8.6 0.6 9.6 0.5 3.9 7.6 8.6 2.8 1.6 0.0 0.0 7.4 0.8 1.8 0.0 1.4 12.6 7.0 137.3 21.7 3.0 0.0 2.2 0.5 42.4 185.5 27.0 6.3 7.0 11.5 38.6 0.8 4.7 1.7 1.5 4.1 0.0 36.6 39.6 19.6 271.5 14.8 48.0 9.4 41.5 5.1 3.1 54.3 0.6 0.9 0.3 265.9 0.9 17.1 0.2 0.1 0.9 0.7 92.1 146.2 341.2 1.0 1.9 3.7 42.8 9.0 5.4 5.7 2.2 6.5 CRLF1 "CISS, CISS1, CLF, CLF-1" ENSG00000006016 "Cytokine receptor like factor 1" O75462 19 18572220-18607741 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 88.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Basal keratinocytes: 9.7;Fibroblasts: 16.0;Respiratory ciliated cells: 11.9;Skeletal myocytes: 19.9;Smooth muscle cells: 10.5" "Group enriched" "Detected in all" 4 "lung cancer: 27.4;thyroid cancer: 36.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "ASC diff: 1048.7;Hep G2: 458.8" "Region enriched" "Detected in many" 7 "hippocampal formation: 21.1" "Group enriched" "Detected in some" 6 "cerebellum: 2.3;spinal cord: 8.6" "HPA041493, HPA041793" Approved "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041493: AB_10795637, HPA041793: AB_10804117" "unprognostic (1.97e-1)" "unprognostic (2.29e-1)" "unprognostic (2.34e-3)" "unprognostic (9.31e-3)" "unprognostic (1.58e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (4.95e-2)" "unprognostic (7.92e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (5.27e-3)" 40.1 14.5 18.7 0.9 24.6 0.0 18.7 22.4 51.7 25.7 11.2 8.9 0.5 12.8 0.9 17.4 11.3 1.4 88.5 22.0 13.5 7.7 1.5 16.0 0.4 24.3 28.0 4.5 8.9 0.5 8.9 11.3 17.8 8.9 0.4 0.1 14.9 6.2 21.4 27.3 5.0 1.5 18.7 2.4 7.5 1.3 13.4 0.3 50.3 0.9 0.2 9.3 15.5 25.5 0.0 0.0 0.0 10.7 1048.7 15.3 5.2 5.4 0.0 0.0 0.0 0.1 0.0 0.0 66.5 33.2 1.9 0.4 10.8 0.2 0.0 0.0 1.4 0.0 18.1 458.8 7.5 0.1 0.5 12.0 1.0 0.2 0.3 1.6 0.3 0.0 0.1 0.2 0.3 16.6 0.0 0.0 1.2 0.1 0.3 0.0 9.1 0.1 0.0 0.5 0.0 0.1 14.2 0.0 0.0 2.0 13.0 0.6 1.3 0.1 11.1 0.8 0.4 0.1 0.0 0.5 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 24.6 22.4 51.7 22.0 13.5 24.3 28.0 17.8 18.7 13.4 25.5 0.4 0.0 0.0 15.3 0.3 9.7 0.6 6.8 0.0 0.2 0.7 4.2 2.5 0.0 2.6 0.0 0.0 0.1 0.3 0.1 5.9 0.3 6.9 2.6 1.9 0.5 0.0 0.0 7.8 0.2 1.3 16.0 0.5 0.5 0.0 0.2 0.4 0.1 0.3 0.0 1.0 0.0 2.0 0.0 1.0 0.4 0.0 0.4 0.0 0.0 0.1 0.9 1.0 0.5 0.8 0.2 0.0 0.0 0.0 0.3 0.0 0.3 11.9 1.3 0.0 19.9 10.5 0.2 2.2 0.6 4.5 0.3 0.6 0.2 0.1 0.3 CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "liver: 9388.5" "Group enriched" "Detected in some" 16 "Ductal cells: 1087.7;Hepatocytes: 4142.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 1010.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 6.3;U-2 OS: 4.5;U-266/84: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" NA NA 2920000000 5200000000 "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: AB_562362, HPA027367: AB_1847216, HPA027396: AB_1847217" "unprognostic (3.74e-1)" "unprognostic (5.31e-2)" "unprognostic (2.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (4.17e-10)" "unprognostic (3.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.60e-2)" "unprognostic (6.61e-2)" 3.4 0.7 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.3 0.0 3.1 0.0 0.5 0.4 111.7 0.7 0.0 0.0 0.7 9388.5 0.5 0.1 0.0 0.0 0.4 118.5 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.3 0.6 0.5 0.0 0.0 6.1 0.4 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.8 0.0 11.7 1.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 118.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1087.7 1.4 0.0 0.1 6.3 0.0 163.2 0.0 63.2 0.0 0.0 0.0 0.2 0.0 0.0 89.6 4142.7 0.1 0.0 0.0 0.0 0.0 98.8 0.3 0.7 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 60.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.6;fallopian tube: 38.2;lung: 50.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 119.5;Club cells: 36.4;Inhibitory neurons: 63.6;Oligodendrocyte precursor cells: 54.8" "Cancer enhanced" "Detected in many" "melanoma: 43.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 3.0;HMC-1: 2.5;HUVEC TERT2: 7.1;SCLC-21H: 4.7;SK-MEL-30: 7.7;TIME: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" NA NA 550000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "HPA008175: AB_1847254" "unprognostic (2.55e-1)" "unprognostic (6.41e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.54e-1)" "unprognostic (6.96e-3)" "unprognostic (9.30e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (1.69e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.70e-4)" "unprognostic (1.05e-2)" "unprognostic (3.29e-3)" "prognostic favorable (1.51e-4)" 4.4 0.8 8.7 1.1 23.7 0.0 2.4 10.9 20.1 6.4 0.9 11.5 0.5 1.3 3.8 8.3 38.2 0.3 10.6 9.1 8.1 4.3 0.4 50.0 0.4 45.1 10.2 0.7 1.3 0.8 5.3 0.0 45.6 2.3 0.4 11.3 3.4 33.6 1.1 4.1 2.3 0.8 12.6 0.1 1.8 3.9 18.5 0.2 4.7 1.5 0.3 30.2 4.9 15.5 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 3.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 4.7 1.1 0.5 0.0 7.7 0.3 0.0 0.0 9.4 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 23.7 10.9 20.1 9.1 8.1 45.1 10.2 45.6 12.6 18.5 15.5 1.9 22.4 119.5 2.9 0.0 1.5 2.7 1.3 5.7 10.1 2.6 2.8 7.1 1.5 36.4 9.2 0.0 0.0 0.1 0.0 0.0 4.6 0.1 0.5 0.1 8.8 1.8 0.0 22.9 0.7 0.0 2.3 0.0 0.6 5.1 0.0 5.7 0.1 0.0 0.0 63.6 0.0 0.0 0.6 0.9 0.6 0.0 0.2 8.8 2.8 0.0 14.1 0.0 54.8 6.2 0.6 0.0 0.4 1.2 1.3 0.0 0.0 0.9 5.3 0.0 3.5 0.3 1.5 1.9 13.1 0.4 0.0 0.4 0.0 0.0 1.7 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 2.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 11.4;Basal respiratory cells: 11.3;dendritic cells: 17.7;Ductal cells: 18.3;Pancreatic endocrine cells: 24.9;T-cells: 28.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.2" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.2" "Cell line enriched" "Detected in some" 4 "BJ hTERT+: 91.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" NA NA 23900 "Cluster 15: NK-cells - Transcription" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA057404: AB_2683428, HPA062006: AB_2684654" "unprognostic (7.29e-2)" "unprognostic (2.49e-3)" "unprognostic (8.77e-2)" "unprognostic (2.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (1.47e-2)" "unprognostic (2.64e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-8)" "unprognostic (4.81e-2)" "unprognostic (1.22e-1)" "unprognostic (9.07e-2)" "unprognostic (2.06e-2)" 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 2.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 9.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 91.3 0.1 5.1 0.0 7.4 0.0 1.5 0.0 5.3 0.2 0.0 6.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 20.8 13.8 2.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.3 3.8 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 11.4 0.0 0.3 1.5 0.1 11.3 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 17.7 0.1 0.0 18.3 0.0 0.3 0.2 4.8 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.7 1.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.6 0.0 28.6 0.0 0.0 1.1 CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 64.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 248.5;Extravillous trophoblasts: 124.6;Langerhans cells: 365.1;Macrophages: 114.5;monocytes: 575.2;Syncytiotrophoblasts: 312.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 320.2" "Group enriched" "Detected in all" 30 "dendritic cells: 170.7;granulocytes: 320.2;monocytes: 161.1" "Group enriched" "Detected in some" 7 "BEWO: 194.0;HMC-1: 58.3;SK-MEL-30: 142.0" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" NA NA 13000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "CAB016148: AB_626868" "unprognostic (4.19e-2)" "prognostic favorable (2.38e-5)" "unprognostic (5.47e-2)" "unprognostic (4.33e-2)" "unprognostic (4.88e-2)" "prognostic favorable (2.81e-4)" "unprognostic (8.24e-2)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (8.48e-2)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (5.53e-4)" "unprognostic (3.60e-1)" "unprognostic (9.44e-2)" 10.0 5.5 4.2 25.4 4.4 21.7 6.8 5.2 4.8 5.1 5.4 5.8 5.8 2.5 1.7 5.3 4.1 12.6 2.5 4.0 5.4 2.3 4.6 14.2 20.9 8.5 6.6 1.8 3.3 3.1 1.4 64.4 8.3 2.5 7.4 0.7 3.0 3.0 0.6 4.0 6.6 7.1 7.2 14.9 5.0 1.1 9.0 9.4 1.6 2.0 23.5 12.7 1.5 11.9 0.3 11.5 0.5 0.0 0.0 0.0 194.0 0.3 0.5 0.4 0.1 4.2 1.0 0.2 12.6 0.0 10.3 0.2 0.1 0.0 0.0 3.9 0.1 0.2 8.0 0.1 0.0 4.6 58.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.2 0.4 18.8 1.6 1.8 0.4 0.2 0.5 0.3 0.0 0.5 0.1 0.3 3.7 0.1 142.0 15.1 9.4 16.8 0.0 0.2 5.5 0.1 0.0 0.1 0.1 0.6 0.0 18.5 0.1 17.4 161.1 200.3 0.4 94.9 1.0 2.3 0.3 0.3 170.7 0.6 0.4 0.3 320.2 7.3 48.7 164.0 1.1 65.5 4.2 4.4 5.2 4.8 4.0 5.4 8.5 6.6 8.3 7.2 9.0 11.9 1.2 0.0 7.3 1.3 5.5 7.8 0.9 0.1 0.6 0.6 6.3 2.5 1.2 2.8 3.6 1.8 0.0 248.5 38.3 0.0 0.0 0.3 0.6 7.8 1.2 5.3 0.0 1.3 1.4 1.8 124.6 3.4 0.0 14.7 10.1 0.5 0.7 0.1 75.5 0.0 1.7 0.0 2.0 74.8 365.1 0.3 0.9 114.5 8.8 66.5 575.2 0.3 0.0 1.5 0.9 0.2 0.0 0.4 1.0 0.5 0.0 0.1 2.7 1.5 6.6 1.8 1.4 0.2 0.4 0.0 5.3 312.5 3.3 0.1 0.0 2.5 CSF3 "C17orf33, G-CSF, GCSF, MGC45931" ENSG00000108342 "Colony stimulating factor 3" P09919 17 40015361-40017813 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 123.0;urinary bladder: 57.5" "Cell type enhanced" "Detected in some" "Adipocytes: 57.0;Alveolar cells type 2: 121.2;Basal respiratory cells: 155.9;Club cells: 85.8;Endothelial cells: 192.1;Fibroblasts: 101.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 74.8;U-87 MG: 286.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 6170 "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.59e-3)" "unprognostic (1.57e-2)" "unprognostic (1.73e-1)" "prognostic favorable (8.45e-4)" "unprognostic (1.06e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-2)" "unprognostic (1.74e-1)" "unprognostic (2.26e-1)" "unprognostic (2.82e-2)" "unprognostic (7.40e-4)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (4.10e-2)" "unprognostic (4.80e-3)" 41.7 5.9 1.3 14.2 1.2 3.5 7.3 0.9 1.5 25.2 0.7 8.5 0.0 4.1 0.0 6.2 7.2 2.3 16.5 1.1 1.0 3.1 0.5 123.0 0.3 2.0 1.2 1.9 3.8 0.3 10.2 2.5 1.6 16.1 0.5 0.3 3.0 0.1 21.7 1.8 4.3 1.6 2.0 0.9 8.0 1.3 1.3 0.3 3.9 10.5 0.4 57.5 5.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 74.8 0.0 2.8 0.2 0.0 0.0 1.0 0.0 3.2 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 36.0 11.6 0.0 9.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 286.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.9 1.5 1.1 1.0 2.0 1.2 1.6 2.0 1.3 1.1 57.0 22.4 121.2 0.0 0.0 34.5 5.3 155.9 0.0 0.0 0.1 0.1 0.1 0.0 85.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 11.4 0.8 192.1 0.0 0.0 0.0 0.2 0.0 101.5 5.6 23.6 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 18.3 0.0 36.5 0.0 0.0 2.2 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 14.0 0.0 0.0 34.9 0.0 0.0 37.3 6.4 0.2 0.9 0.9 33.5 0.0 3.2 0.0 0.8 17.3 CSH1 "CSA, CSMT, FLJ75407, hCS-A, PL" ENSG00000136488 "Chorionic somatomammotropin hormone 1" P0DML2 17 63894909-63896661 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 247 "placenta: 9786.7" "Group enriched" "Detected in some" 24 "Extravillous trophoblasts: 542.0;Syncytiotrophoblasts: 1092.3" "Cancer enriched" "Detected in single" 8 "testis cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 11.8;SuSa: 17.0" "CAB026374, HPA043715" Enhanced "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB026374: , HPA043715: AB_2678632" "unprognostic (6.99e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 6.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.7 3.9 0.0 0.2 9786.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 39.6 0.0 26.1 19.9 0.1 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 542.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1092.3 0.0 0.0 0.0 0.0 CSH2 "CS-2, CSB, hCS-B" ENSG00000213218 "Chorionic somatomammotropin hormone 2" P0DML3 17 63872012-63873766 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 218 "placenta: 3289.0" "Cell type enriched" "Detected in some" 12 "Syncytiotrophoblasts: 275.5" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "BEWO: 9.3;SuSa: 13.1" HPA043715 Supported "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA043715: AB_2678632" "unprognostic (1.68e-1)" "unprognostic (1.85e-1)" "unprognostic (1.86e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 1.1 0.0 1.9 3289.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 15.0 0.0 8.6 5.2 0.2 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 275.5 0.0 0.0 0.0 0.0 CSHL1 "CS-5, CSHP1, CSL, hCS-L, MGC149868" ENSG00000204414 "Chorionic somatomammotropin hormone like 1" Q14406 17 63909597-63918838 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "placenta: 150.0" "Cell type enriched" "Detected in some" 12 "Syncytiotrophoblasts: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025646, HPA043715" Enhanced "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB025646: , HPA043715: AB_2678632" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.4 150.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 21.6 0.0 0.0 0.0 0.0 CSN1S1 "CASA, CSN1" ENSG00000126545 "Casein alpha s1" P47710 4 69931068-69946574 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "breast: 1391.5" "Cell type enriched" "Detected in some" 47 "Breast glandular cells: 8261.0" "Cancer enriched" "Detected in some" 10 "breast cancer: 17.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035659, HPA057031" Enhanced "Secreted in female reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA035659: AB_10696356, HPA057031: AB_2683315" "unprognostic (1.52e-2)" "unprognostic (1.01e-1)" 16.0 0.0 0.1 0.5 0.0 0.0 1391.5 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.4 1.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.2 0.0 0.1 0.0 0.4 0.1 28.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 8261.0 172.2 2.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.1 0.3 0.0 2.1 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.0 0.0 CSN2 CASB ENSG00000135222 "Casein beta" P05814 4 69955256-69961007 "Predicted secreted proteins" "Milk protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 94 "breast: 307.2" "Cell type enriched" "Detected in some" 97 "Breast glandular cells: 33136.9" "Cancer enriched" "Detected in single" 156 "breast cancer: 75.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041036 Supported "Secreted in female reproductive system" NA NA "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA041036: AB_10793865" 0.0 0.0 0.0 0.0 0.0 0.0 307.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.1 0.0 0.0 0.0 29.8 0.0 0.0 0.0 0.0 0.0 33136.9 340.4 0.0 0.0 0.0 0.0 0.0 0.0 72.4 0.0 0.0 0.0 0.8 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 CSN3 CSN10 ENSG00000171209 "Casein kappa" P07498 4 70242588-70251428 "Predicted secreted proteins" "Milk protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 378.1" "Cell type enriched" "Detected in some" 48 "Breast glandular cells: 2554.0" "Cancer enriched" "Detected in some" 5 "breast cancer: 35.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035953, HPA035954" Enhanced "Secreted in female reproductive system" NA NA "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA035953: AB_10673226, HPA035954: AB_2674884" 0.0 0.0 0.0 0.0 0.0 0.0 378.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 10.3 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 2554.0 52.2 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.1 3.7 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.9 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 CST1 ENSG00000170373 "Cystatin SN" P01037 20 23747562-23751268 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 119 "salivary gland: 28401.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 14.3;Collecting duct cells: 79.1;Glandular and luminal cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 1142.2" "CAB026769, HPA043706, HPA044763" Enhanced "Secreted to digestive system" NA NA 6300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB026769: , HPA043706: AB_2678627, HPA044763: AB_2679080" "prognostic favorable (4.00e-4)" "unprognostic (2.47e-1)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (1.99e-1)" "unprognostic (5.27e-2)" "unprognostic (1.99e-1)" "unprognostic (1.56e-1)" "unprognostic (1.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (8.26e-2)" "unprognostic (9.58e-2)" "unprognostic (2.58e-1)" "unprognostic (9.00e-2)" "unprognostic (9.91e-3)" 0.1 0.3 0.1 1.1 0.1 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.0 3.7 0.4 0.1 0.2 238.8 8.0 0.1 0.1 0.0 0.0 0.1 0.0 0.8 0.7 7.1 37.3 0.0 0.1 4.1 1.4 13.0 0.2 0.0 28401.8 0.6 0.0 3.2 0.0 0.0 0.4 0.0 0.8 0.2 0.1 2.1 0.0 0.0 0.7 0.7 0.0 0.4 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 172.6 0.3 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.4 0.0 0.1 0.0 0.1 0.0 51.2 0.0 4.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 45.3 0.1 0.0 0.0 0.0 4.4 1142.2 0.7 0.0 0.1 0.0 0.3 5.6 0.0 0.0 223.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.8 0.7 1.4 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 14.3 0.0 79.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 5.7 2.2 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 31.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.5 0.0 0.1 0.0 0.4 0.0 0.0 0.5 CST11 "CST8L, CTES2, dJ322G13.6" ENSG00000125831 "Cystatin 11" Q9H112 20 23450403-23452876 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 473 "epididymis: 210.7" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Endometrial stromal cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053399 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 36: Stromal cells - Cell proliferation" "HPA053399: AB_2682136" "unprognostic (9.42e-2)" "unprognostic (2.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 210.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.3 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CST2 ENSG00000170369 "Cystatin SA" P09228 20 23823769-23826729 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 637 "salivary gland: 5987.1" "Group enriched" "Detected in some" 4 "Granulosa cells: 5.2;Melanocytes: 16.0" "Cancer enhanced" "Detected in many" "prostate cancer: 24.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "RT4: 67.7" "CAB024963, HPA043706, HPA044763" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "CAB024963: , HPA043706: AB_2678627, HPA044763: AB_2679080" "unprognostic (1.57e-2)" "unprognostic (3.23e-2)" "unprognostic (1.04e-1)" "unprognostic (3.10e-1)" "unprognostic (1.64e-2)" "unprognostic (5.17e-3)" "unprognostic (1.28e-2)" "unprognostic (2.75e-3)" "unprognostic (2.73e-1)" "unprognostic (4.82e-3)" "unprognostic (6.43e-3)" "unprognostic (2.51e-1)" "unprognostic (4.58e-11)" "unprognostic (1.29e-3)" "unprognostic (3.22e-1)" "unprognostic (4.30e-1)" "unprognostic (1.71e-1)" 1.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.1 0.2 0.1 0.0 0.2 4.8 2.4 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 1.6 9.3 0.1 2.0 1.0 0.0 2.5 0.0 0.0 5987.1 1.3 0.0 0.4 0.2 3.8 0.0 0.1 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 1.8 67.7 0.0 0.0 0.0 0.0 5.4 0.9 0.0 0.0 4.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.4 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 16.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CST4 ENSG00000101441 "Cystatin S" P01036 20 23685640-23689038 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 514 "salivary gland: 29036.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.7;Collecting duct cells: 9.2;Glandular and luminal cells: 3.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CACO-2: 5.5;RT4: 13.6" "HPA043706, HPA044763" Supported "Secreted to digestive system" NA NA 2800000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA043706: AB_2678627, HPA044763: AB_2679080" "unprognostic (2.80e-1)" "unprognostic (7.88e-2)" "unprognostic (2.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (4.98e-5)" "unprognostic (1.00e-2)" "unprognostic (9.52e-2)" "unprognostic (2.11e-2)" "unprognostic (2.31e-1)" "unprognostic (7.95e-2)" "prognostic favorable (2.88e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 56.4 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 29.9 0.0 0.0 3.8 0.0 2.4 0.0 0.0 29036.2 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 13.6 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 CST5 ENSG00000170367 "Cystatin D" P28325 20 23875934-23879748 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 959 "salivary gland: 2156.1" "Group enriched" "Detected in some" 8 "Alveolar cells type 1: 9.6;Langerhans cells: 3.4" "Cancer enriched" "Detected in many" 5 "breast cancer: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB024944, HPA061449" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: Alveolar cells - Smell perception" "CAB024944: , HPA061449: AB_2684523" "unprognostic (2.43e-1)" "unprognostic (8.83e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-1)" "unprognostic (1.51e-2)" "unprognostic (4.73e-1)" "unprognostic (4.31e-2)" "unprognostic (1.76e-2)" "unprognostic (2.32e-1)" "unprognostic (1.35e-1)" "unprognostic (4.83e-3)" "unprognostic (5.14e-2)" "unprognostic (2.31e-1)" 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.3 0.4 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2156.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 761.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Club cells: 115.2;Pancreatic endocrine cells: 368.1;Respiratory ciliated cells: 404.0" "Group enriched" "Detected in many" 5 "thyroid cancer: 171.0;urothelial cancer: 43.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 130.2;CAPAN-2: 364.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 82000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "CAB019316: , HPA044963: AB_2679158" "unprognostic (3.01e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (5.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (5.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.29e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (5.89e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-2)" "unprognostic (2.59e-2)" 3.2 0.3 0.1 0.3 0.1 0.2 28.5 0.8 0.4 7.4 0.8 0.4 0.0 0.3 0.6 34.6 14.9 0.5 2.8 0.1 0.3 2.6 0.3 18.3 0.0 0.2 0.2 0.7 0.7 2.1 1.6 8.1 0.1 0.9 0.0 0.0 7.4 4.9 2.0 761.4 0.3 0.1 0.1 0.2 0.6 1.8 0.4 2.7 21.4 0.0 2.2 1.2 22.5 0.2 130.2 0.0 0.0 0.6 0.0 0.0 37.6 1.4 0.0 0.3 0.2 1.0 364.6 0.0 1.8 5.1 0.1 4.5 0.0 32.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.5 0.8 0.2 0.7 0.0 0.0 35.8 0.4 0.1 0.8 0.1 0.0 0.2 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.4 0.1 0.3 0.2 0.2 0.1 0.1 0.4 0.2 0.1 93.0 6.1 0.0 0.6 1.1 1.7 41.4 0.6 0.0 5.3 7.1 1.2 0.0 115.2 58.8 0.0 33.3 0.0 0.1 0.0 57.4 0.2 7.7 0.1 0.9 0.0 0.0 0.0 21.6 24.4 2.0 0.0 0.6 21.6 0.1 0.4 0.1 41.1 0.0 0.0 0.0 24.4 1.4 10.0 0.8 0.0 5.3 5.4 0.0 1.1 1.3 0.0 0.0 0.0 368.1 1.1 0.4 9.8 1.9 0.0 0.5 404.0 0.1 0.0 0.3 16.0 5.2 17.6 1.0 27.6 64.2 0.7 0.0 0.4 6.1 CST7 ENSG00000077984 "Cystatin F" O76096 20 24949269-24959928 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 1095.6" "Group enriched" "Detected in many" 9 "dendritic cells: 1094.4;Langerhans cells: 541.7;monocytes: 659.7;NK-cells: 1385.2;T-cells: 544.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 1287.0" "Group enriched" "Detected in all" 27 "granulocytes: 342.2;NK-cells: 655.3;T-cells: 1287.0" "Cell line enhanced" "Detected in some" "HL-60: 77.8;HMC-1: 204.6;NB-4: 212.1;U-937: 380.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Low region specificity" "Detected in all" HPA040442 Enhanced "Secreted to blood" NA NA 26000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA040442: AB_2676988" "prognostic favorable (6.55e-4)" "prognostic favorable (7.90e-4)" "unprognostic (9.37e-2)" "prognostic favorable (9.17e-6)" "unprognostic (2.38e-2)" "prognostic favorable (5.85e-5)" "unprognostic (1.00e-2)" "unprognostic (8.66e-2)" "unprognostic (2.84e-3)" "unprognostic (7.93e-2)" "unprognostic (5.05e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (4.37e-6)" "unprognostic (7.64e-2)" "unprognostic (3.38e-1)" "unprognostic (4.45e-1)" "unprognostic (7.62e-2)" 18.0 3.6 1.3 24.2 1.6 1095.6 5.7 2.8 5.1 4.5 1.7 5.7 5.9 4.6 4.8 5.4 10.4 17.7 5.6 1.5 1.4 5.4 12.7 49.3 73.4 2.4 1.4 2.5 3.9 1.0 2.2 4.4 2.0 4.3 5.1 0.2 6.6 2.0 1.9 4.5 13.9 5.0 1.6 148.1 8.7 1.7 1.6 17.3 5.6 4.4 16.4 19.2 5.2 1.4 0.3 0.6 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.3 1.7 0.0 0.4 0.0 77.8 204.6 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 2.8 0.0 0.2 2.0 212.1 0.1 0.0 0.2 0.5 7.7 0.1 0.0 0.1 0.3 0.2 0.0 0.1 1.0 0.1 0.0 13.3 0.2 0.1 0.8 0.2 0.5 0.1 0.1 0.2 0.1 380.4 0.1 74.3 3.0 10.4 1287.0 3.4 720.2 3.7 186.8 904.7 28.4 3.9 38.8 531.2 342.2 655.3 3.5 7.2 123.0 600.8 1.3 1.6 2.8 5.1 1.5 1.4 2.4 1.4 2.0 1.6 1.6 1.4 8.1 9.6 14.1 0.0 14.5 22.8 0.3 0.0 0.0 0.0 2.5 2.4 1.4 4.3 0.6 0.0 0.0 0.2 1094.4 0.3 0.0 1.3 0.0 1.3 0.7 3.2 0.0 46.7 0.0 3.7 0.1 5.2 11.2 1.2 60.0 0.0 11.0 3.8 1.4 0.0 0.0 0.1 0.0 16.2 541.7 0.0 0.0 61.9 24.9 1.9 659.7 0.0 1385.2 0.0 0.1 0.2 0.1 0.0 90.9 0.1 0.4 2.3 2.2 0.0 0.0 2.2 3.6 0.0 0.2 0.5 23.9 1.1 544.5 0.0 0.6 0.6 CST8 "CRES, CTES5" ENSG00000125815 "Cystatin 8" O60676 20 23491101-23496010 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 203 "testis: 22.3" "Group enriched" "Detected in some" 128 "Early spermatids: 188.7;Late spermatids: 119.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 119.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CST9 "CLM, CTES7A" ENSG00000173335 "Cystatin 9" Q5W186 20 23602410-23605917 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "breast: 1.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 37 "breast cancer: 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA029190 Uncertain "Secreted in female reproductive system" NA NA "Cluster 5: Breast - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA029190: AB_10602804" "unprognostic (2.06e-2)" "unprognostic (2.21e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CST9L "bA218C14.1, CTES7B" ENSG00000101435 "Cystatin 9 like" Q9H4G1 20 23564732-23568484 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 337 "epididymis: 26.4;testis: 87.9" "Cell type enhanced" "Detected in some" "Early spermatids: 4.0;Late spermatids: 13.2;Leydig cells: 2.5;Peritubular cells: 1.5;Spermatocytes: 1.6" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 20 "HEL: 2.1" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (2.10e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CSTL1 "CTES1, dJ322G13.4" ENSG00000125823 "Cystatin like 1" Q9H114 20 23439685-23444930 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "testis: 4.4" "Group enriched" "Detected in some" 631 "Early spermatids: 51.3;Late spermatids: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.14e-1)" "unprognostic (1.54e-1)" "unprognostic (3.25e-3)" "unprognostic (2.04e-1)" "unprognostic (6.58e-2)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (3.63e-1)" "unprognostic (2.97e-1)" "unprognostic (6.87e-2)" "unprognostic (2.35e-1)" "unprognostic (5.36e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CT55 "CXorf48, FLJ20527" ENSG00000169551 "Cancer/testis antigen 55" Q8WUE5 X 135156540-135171398 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 3.8" "Group enriched" "Detected in some" 46 "Spermatocytes: 43.8;Spermatogonia: 57.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "K-562: 7.6" HPA059575 Approved Vesicles "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA059575: " "unprognostic (6.20e-2)" "unprognostic (1.39e-1)" "unprognostic (8.36e-2)" "unprognostic (5.86e-3)" "unprognostic (3.47e-1)" "unprognostic (2.67e-1)" "unprognostic (4.44e-2)" "unprognostic (1.49e-1)" 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.8 57.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CTF1 "CT-1, CT1" ENSG00000150281 "Cardiotrophin 1" Q16619 16 30896614-30903547 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 16.4;Cardiomyocytes: 11.4;Distal tubular cells: 31.3;Muller glia cells: 21.1;Proximal tubular cells: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.6;ASC TERT1: 14.7;fHDF/TERT166: 11.9;HHSteC: 13.0;HSkMC: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025853 Uncertain "Secreted to blood" NA NA 11900 "Cluster 6: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "CAB025853: " "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (6.81e-3)" "unprognostic (1.06e-3)" "prognostic unfavorable (7.22e-5)" "unprognostic (2.12e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.87e-4)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (6.75e-2)" "unprognostic (2.76e-2)" "unprognostic (1.76e-3)" "unprognostic (5.07e-3)" "unprognostic (2.06e-1)" "unprognostic (2.16e-2)" "unprognostic (1.79e-1)" 6.4 8.1 4.8 1.3 4.7 1.5 6.7 4.1 5.2 14.7 5.3 13.4 0.8 17.3 4.2 5.3 12.1 3.8 16.0 4.5 4.5 10.2 1.2 7.4 1.3 5.3 5.8 18.4 3.6 10.0 5.2 2.0 4.7 12.2 1.0 2.1 5.7 12.7 14.1 2.7 4.6 7.6 5.5 1.7 7.6 3.4 5.0 2.1 8.5 10.9 1.1 14.0 9.6 5.0 2.0 0.3 2.6 5.7 13.6 14.7 4.5 4.3 8.5 4.4 5.6 2.4 0.4 0.1 8.3 11.9 0.4 1.5 0.0 3.0 4.4 0.1 0.2 0.1 0.2 0.9 13.0 0.2 0.8 13.9 3.8 3.3 8.0 4.9 1.2 0.2 3.7 0.4 7.9 0.3 0.3 0.4 0.8 1.2 0.8 1.6 3.9 0.0 0.7 0.9 0.2 1.4 0.0 0.1 0.0 4.0 6.9 0.3 0.9 4.2 5.2 0.2 0.1 0.1 0.1 0.2 3.3 0.5 0.0 0.6 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.1 0.3 0.0 0.0 4.8 4.7 4.1 5.2 4.5 4.5 5.3 5.8 4.7 5.5 5.0 5.0 0.8 3.2 6.4 2.6 0.8 0.4 16.4 1.8 2.2 0.3 6.2 7.1 11.4 2.8 1.8 7.3 0.0 0.3 1.2 0.0 31.3 1.0 0.6 7.1 2.9 1.1 0.0 0.4 0.3 0.4 0.2 3.9 0.0 2.4 0.0 3.8 0.0 0.4 0.6 0.0 0.6 0.2 0.0 0.6 0.8 0.7 2.1 1.1 0.0 1.0 0.4 21.1 0.0 1.0 0.4 0.4 0.0 2.6 0.6 2.7 0.2 14.4 2.5 0.9 0.0 4.6 3.0 0.8 0.4 1.9 0.3 0.4 0.7 3.9 0.2 7.4 CTHRC1 ENSG00000164932 "Collagen triple helix repeat containing 1" Q96CG8 8 103371538-103382989 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.1;gallbladder: 87.8;placenta: 90.1;urinary bladder: 84.6" "Cell type enhanced" "Detected in many" "Endothelial cells: 95.2;Fibroblasts: 181.6;Langerhans cells: 45.9;Melanocytes: 49.8;Smooth muscle cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 294.6;fHDF/TERT166: 138.1;HHSteC: 197.1;HSkMC: 406.6;WM-115: 386.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059806, HPA061896" Approved Approved Nucleoplasm "Secreted in other tissues" NA NA 420000 "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA059806: AB_2684130, HPA061896: AB_2684633" "unprognostic (2.04e-2)" "unprognostic (4.58e-1)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.17e-2)" "unprognostic (3.64e-2)" "unprognostic (8.63e-2)" "unprognostic (1.12e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.22e-14)" "unprognostic (2.33e-3)" "unprognostic (3.21e-2)" "unprognostic (7.96e-3)" "unprognostic (2.37e-3)" 69.1 2.8 1.6 15.4 1.8 0.5 39.0 5.7 6.3 12.8 0.4 6.6 6.3 18.7 3.3 9.7 5.3 87.8 8.9 1.5 2.3 2.3 0.8 8.9 13.8 2.0 1.6 4.2 3.7 2.2 3.7 90.1 2.5 4.7 6.2 2.4 17.0 5.6 3.6 32.5 3.5 19.7 1.8 2.6 3.6 3.6 1.5 6.2 9.1 4.1 16.0 84.6 6.6 3.3 12.1 0.9 3.3 0.8 90.6 294.6 0.2 34.8 9.3 3.7 5.0 1.1 8.3 1.5 36.6 138.1 0.2 0.4 0.1 0.2 17.7 0.5 0.0 0.5 0.6 19.2 197.1 0.9 0.7 406.6 0.5 30.7 0.4 1.4 60.2 2.3 0.5 91.6 18.7 1.7 17.2 41.1 11.0 0.4 58.0 35.8 30.9 1.1 2.9 0.2 5.7 4.3 0.1 0.2 110.8 12.6 0.1 0.2 49.0 4.6 1.8 4.8 0.4 3.0 0.8 0.6 2.2 0.2 386.9 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.1 1.6 1.8 5.7 6.3 1.5 2.3 2.0 1.6 2.5 1.8 1.5 3.3 36.9 3.2 2.3 1.0 6.7 32.0 0.2 12.1 0.0 0.3 0.9 1.4 0.8 1.5 3.6 3.7 0.0 5.6 0.9 0.0 0.0 4.1 0.5 6.4 9.8 95.2 1.2 0.8 2.3 0.6 11.3 181.6 0.0 11.5 0.0 0.5 17.5 0.1 8.0 0.0 2.0 0.0 4.1 0.3 45.9 0.8 12.5 0.9 49.8 3.7 0.6 5.5 1.0 4.5 1.8 1.8 0.0 0.4 24.2 0.8 0.0 0.5 0.8 1.2 0.0 4.7 77.4 4.3 16.5 0.3 27.3 16.6 3.5 1.2 0.2 0.5 CTRB1 CTRB ENSG00000168925 "Chymotrypsinogen B1" P17538 16 75218988-75226338 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2384 "pancreas: 133851.7" "Cell type enriched" "Detected in some" 21 "Exocrine glandular cells: 31269.6" "Cancer enriched" "Detected in some" 1905 "pancreatic cancer: 962.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.2;HDLM-2: 1.6" "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (5.22e-2)" "unprognostic (4.43e-3)" "unprognostic (2.96e-1)" "unprognostic (1.17e-2)" 25.5 5.1 0.2 2.1 0.2 1.0 9.5 0.5 0.3 10.4 0.0 4.3 16.6 4.2 0.5 6.8 3.0 0.0 22.3 0.0 0.0 4.4 13.2 2.9 2.6 0.1 0.1 56.1 133851.7 0.0 7.2 6.5 0.1 5.6 0.0 0.0 22.3 0.2 3.8 5.8 8.9 0.0 0.0 11.7 7.6 3.4 0.1 0.0 2.8 0.1 0.0 2.4 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.1 0.1 2.0 0.0 0.0 0.1 31269.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 151.9 0.0 0.0 0.0 0.1 1430.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204103-75207161 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2443 "pancreas: 98661.0" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 53114.3" "Cancer enriched" "Detected in single" 1696 "pancreatic cancer: 540.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.4;U-2 OS: 5.8;U-251 MG: 1.6;U-266/84: 1.8;U-698: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (9.41e-4)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "unprognostic (2.77e-1)" "unprognostic (5.95e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-3)" "unprognostic (7.06e-2)" "unprognostic (2.17e-1)" "unprognostic (7.57e-2)" 27.8 4.8 0.2 1.5 0.2 1.8 9.1 0.4 0.3 8.2 0.0 4.4 9.1 4.7 0.1 6.6 3.7 0.2 13.7 0.1 0.2 4.5 12.8 3.1 2.8 0.2 0.1 40.3 98661.0 0.0 5.7 5.6 0.2 11.8 0.0 0.0 16.7 0.1 3.7 5.2 6.6 0.0 0.1 7.2 8.1 3.7 0.2 0.0 3.1 0.0 0.0 2.8 4.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 0.0 1.6 0.0 1.8 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 108.8 2.0 0.3 0.0 1.5 0.0 0.0 0.0 53114.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.3 6.0 0.0 0.0 215.5 0.0 0.0 0.0 0.0 5324.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 30.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438442-15449242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3927 "pancreas: 25708.5" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 6566.4" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046920 Enhanced "Secreted to digestive system" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA046920: AB_2679865" "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" 6.5 1.2 0.2 0.2 0.2 0.7 2.9 0.7 0.3 2.7 0.2 1.2 1.1 1.3 0.1 1.9 0.8 0.0 2.3 0.3 0.1 1.2 3.5 1.0 0.3 0.1 0.1 5.6 25708.5 0.0 1.5 0.7 0.2 1.8 0.0 0.1 2.1 0.0 1.0 2.1 1.7 0.0 0.0 2.0 2.3 1.0 0.2 0.0 1.0 0.0 0.0 0.6 1.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.0 0.2 0.2 0.7 0.3 0.3 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 17.3 0.0 0.6 1.0 0.7 0.0 0.0 0.2 6566.4 0.1 0.2 0.0 2.1 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.9 0.0 0.0 1.1 1.8 0.0 24.3 0.0 1.0 0.0 0.0 673.8 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.0 0.0 1.3 3.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.3 CTRL ENSG00000141086 "Chymotrypsin like" P40313 16 67927640-67932365 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1154 "pancreas: 7481.6" "Group enriched" "Detected in some" 20 "Exocrine glandular cells: 224.2;Pancreatic endocrine cells: 58.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034504, HPA034505" Enhanced "Secreted to digestive system" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "HPA034504: AB_2674196, HPA034505: AB_10602212" "unprognostic (3.03e-5)" "unprognostic (3.53e-3)" "unprognostic (3.46e-2)" "unprognostic (1.37e-1)" "unprognostic (9.66e-2)" "unprognostic (2.00e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (6.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.88e-1)" "unprognostic (3.20e-4)" "unprognostic (6.69e-2)" "unprognostic (2.79e-1)" "unprognostic (2.63e-1)" "unprognostic (1.29e-3)" 1.2 0.7 2.9 1.1 3.1 6.1 0.9 3.8 4.2 1.1 2.1 0.8 1.8 0.6 0.2 0.5 0.7 0.7 1.7 3.0 2.8 0.8 1.0 1.7 2.5 3.5 3.0 6.4 7481.6 0.0 1.7 0.7 3.7 1.2 0.5 0.3 1.1 0.2 0.6 1.0 1.7 0.4 2.8 3.5 1.0 0.6 3.3 1.9 0.7 0.7 1.0 0.7 0.7 3.5 0.4 2.1 0.6 0.2 0.1 0.0 0.9 0.3 0.4 0.7 1.0 1.9 1.0 0.5 0.3 0.4 0.6 0.7 4.1 0.7 2.0 0.8 4.6 0.5 0.9 1.9 0.2 0.3 1.4 0.7 0.1 2.5 0.7 0.3 0.0 1.0 1.0 1.1 0.3 0.7 0.4 2.2 4.1 1.1 1.9 2.0 0.3 3.1 0.0 0.8 1.9 1.1 0.7 0.7 0.4 0.4 0.9 2.5 0.9 0.1 1.4 0.2 1.0 3.8 1.7 2.2 0.1 0.7 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.0 2.9 3.1 3.8 4.2 3.0 2.8 3.5 3.0 3.7 2.8 3.3 3.5 0.6 0.0 0.0 1.6 0.2 0.5 0.0 0.0 2.2 0.0 0.2 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.3 0.8 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.3 224.2 0.0 0.5 1.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 1.7 0.4 2.0 1.2 0.3 0.0 0.0 0.5 0.0 1.0 2.1 0.0 0.0 0.5 1.6 58.5 1.4 0.0 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 0.6 6.9 0.5 0.1 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1475.9;Hofbauer cells: 3763.5;Macrophages: 1512.6;Proximal enterocytes: 1699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 2596.6;hTERT-RPE1: 2780.1;SK-BR-3: 2488.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 318.6 734.6 147.0 204.9 181.9 499.0 244.0 186.0 156.5 270.8 672.7 298.0 387.6 170.7 82.8 319.4 171.6 438.4 444.1 187.8 223.6 691.6 464.8 539.6 241.0 247.6 206.6 130.7 284.8 137.3 131.5 180.7 228.6 138.2 153.4 48.3 422.1 231.7 590.3 340.9 398.3 105.0 188.9 442.0 287.2 88.9 334.4 78.1 182.1 178.2 123.1 296.4 307.5 367.1 204.6 578.9 51.4 246.2 586.5 206.3 112.1 149.4 362.2 161.8 182.8 147.5 2596.6 49.2 376.8 285.8 1265.6 1072.2 63.7 142.6 35.8 206.7 222.9 70.4 92.5 196.5 736.2 171.4 787.7 350.9 621.6 82.5 136.9 2780.1 128.2 62.1 89.2 267.6 263.3 832.6 47.0 110.9 153.1 719.7 247.9 62.5 72.5 191.2 586.6 610.8 84.2 94.8 173.3 2488.5 535.0 68.6 1022.8 232.6 170.3 556.8 92.9 79.0 216.7 432.0 382.3 26.8 867.7 468.6 509.6 211.2 578.7 170.1 156.5 309.9 90.6 28.8 72.1 110.3 144.5 18.8 82.5 107.4 319.5 192.3 265.2 120.3 89.2 489.1 147.0 181.9 186.0 156.5 187.8 223.6 247.6 206.6 228.6 188.9 334.4 367.1 139.3 112.2 228.6 48.3 62.8 72.0 223.5 473.2 71.7 168.6 108.9 113.8 251.9 314.5 459.5 548.1 110.5 211.7 156.1 1475.9 109.5 911.4 3.3 118.1 67.4 128.3 159.6 132.6 18.3 370.1 165.0 157.0 237.5 203.4 474.3 119.4 695.7 678.9 3763.5 264.2 25.2 418.2 498.5 1187.8 67.5 14.6 108.4 1512.6 227.7 20.6 382.6 179.0 256.4 27.2 42.2 392.3 832.5 128.2 122.5 111.7 1699.4 311.8 270.3 102.1 111.7 70.7 135.2 26.6 63.5 141.2 82.1 471.3 155.0 96.0 399.1 357.8 CUTA "ACHAP, C6orf82" ENSG00000112514 "CutA divalent cation tolerance homolog" O60888 6 33416442-33418317 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016787, HPA064369" Uncertain Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 26000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 32: Non-specific - Translation" "Plasma membrane, Focal adhesion sites" "CAB016787: , HPA064369: AB_2685248" "unprognostic (7.03e-2)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (8.91e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.98e-2)" "prognostic favorable (8.50e-4)" "unprognostic (1.87e-1)" "unprognostic (2.78e-2)" "unprognostic (1.27e-3)" "unprognostic (1.91e-1)" "unprognostic (5.55e-2)" "unprognostic (9.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (2.74e-1)" 129.0 268.0 155.3 60.3 165.9 93.9 132.4 166.2 177.1 159.6 196.0 156.7 104.5 158.7 184.8 106.4 144.4 95.1 151.1 159.6 169.9 200.3 217.8 118.3 99.0 166.1 158.3 193.8 186.3 177.2 346.6 81.5 169.6 153.8 71.2 60.3 179.2 113.0 142.8 149.5 129.1 80.1 161.9 147.1 177.5 74.2 160.9 82.7 201.6 89.2 82.5 128.2 121.9 173.0 244.5 142.0 242.7 293.8 177.6 173.9 109.7 224.0 430.1 433.1 462.7 147.5 154.1 166.1 162.2 269.1 316.0 152.4 154.5 231.3 248.9 153.2 295.1 171.8 228.9 397.0 226.3 134.2 135.9 224.7 195.8 209.8 179.8 303.7 118.8 180.9 212.9 348.7 325.1 187.2 222.0 305.1 213.8 222.6 187.5 235.9 141.8 456.4 310.1 112.3 451.7 225.4 136.2 231.3 425.8 135.5 170.8 308.7 121.3 222.6 190.0 166.5 229.8 341.7 363.9 189.5 202.9 304.9 189.3 207.8 179.2 103.6 225.8 138.1 335.1 315.7 360.7 274.6 163.6 266.5 366.5 279.2 25.6 306.9 97.2 120.0 421.9 400.4 155.3 165.9 166.2 177.1 159.6 169.9 166.1 158.3 169.6 161.9 160.9 173.0 109.5 131.4 119.3 14.0 209.5 230.6 287.9 424.5 266.9 92.6 401.0 488.6 138.2 237.4 239.7 316.3 68.8 361.6 186.2 154.0 283.7 188.3 85.4 181.8 177.9 114.7 292.1 111.7 13.0 141.0 235.5 181.4 105.5 156.8 169.9 122.6 134.2 340.1 328.6 77.4 17.4 320.1 360.1 167.1 197.1 345.2 200.0 139.2 316.6 10.3 140.0 179.7 216.3 14.1 31.2 113.3 223.9 191.5 375.7 243.3 306.6 559.1 229.5 85.9 92.1 131.1 226.7 111.0 106.4 203.5 230.4 242.9 242.4 217.8 341.3 268.4 CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 104.8" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal prostatic cells: 50.8;Basal respiratory cells: 51.8;Breast glandular cells: 62.3;Breast myoepithelial cells: 51.1;Club cells: 54.8;Endothelial cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "EFO-21: 30.1;HDLM-2: 86.0;Hep G2: 63.8;RPTEC TERT1: 36.5;SK-BR-3: 21.5" "Low region specificity" "Detected in all" "CAB026192, HPA040361" Approved Supported "Plasma membrane" "Secreted to blood" NA NA 1870000 370000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB026192: , HPA040361: AB_10796453" "unprognostic (6.89e-3)" "prognostic favorable (9.46e-4)" "unprognostic (1.52e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (4.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-2)" "prognostic favorable (8.52e-7)" "unprognostic (5.19e-2)" "unprognostic (2.72e-1)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" 68.3 4.8 36.4 5.7 39.5 0.1 104.8 11.9 44.8 17.6 19.8 14.3 5.1 13.7 8.7 14.4 18.2 21.0 43.0 46.9 26.4 41.9 14.9 98.8 8.5 25.1 24.8 8.3 13.1 7.1 11.2 3.9 23.6 42.2 5.4 4.3 70.8 45.3 15.0 27.3 12.8 10.6 21.8 1.4 14.5 5.7 30.5 5.2 29.7 19.2 6.2 33.0 17.3 31.2 0.0 0.8 8.0 6.8 0.3 0.1 2.0 0.1 0.0 0.0 0.1 3.1 0.0 0.0 30.1 0.1 4.3 0.3 0.0 0.1 0.0 86.0 0.4 0.0 0.0 63.8 0.9 0.0 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 2.8 0.1 0.0 0.1 1.1 0.2 36.5 0.2 0.2 7.1 0.0 21.5 1.9 5.1 0.1 0.2 0.1 0.3 4.7 0.2 2.1 0.1 0.0 0.0 0.1 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 36.4 39.5 11.9 44.8 46.9 26.4 25.1 24.8 23.6 21.8 30.5 31.2 115.4 3.2 4.6 3.3 1.2 4.5 50.8 51.8 31.9 9.8 62.3 51.1 8.3 21.5 54.8 3.7 4.2 0.0 0.8 0.5 0.0 35.1 0.4 12.9 3.3 50.7 1.8 0.0 28.1 1.8 0.1 9.0 0.5 27.3 1.3 0.2 6.1 11.7 0.0 5.0 20.5 0.3 20.3 0.8 4.7 0.5 4.7 0.6 0.0 16.9 0.6 0.8 0.0 13.0 3.2 4.3 0.6 27.8 0.0 29.7 0.2 11.8 28.8 2.2 13.1 2.8 15.7 0.1 0.1 10.3 2.6 0.3 0.8 0.3 1.0 32.6 CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 323.4;Proximal enterocytes: 263.0;Suprabasal keratinocytes: 343.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 93.4;Hep G2: 63.0;NTERA-2: 109.1;RT4: 104.4" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted - unknown location" NA NA 18000 "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" 3.6 2.9 7.0 2.8 8.7 2.6 9.8 6.6 10.8 7.7 22.8 22.5 42.3 5.3 15.2 14.5 10.6 18.3 9.3 8.9 7.1 8.3 49.3 13.6 0.7 10.4 6.8 0.4 15.8 6.8 4.7 0.3 9.3 15.1 25.6 4.9 15.4 14.2 0.4 53.4 42.6 3.3 9.7 2.4 30.9 12.5 7.3 1.5 22.1 0.0 4.1 25.6 10.9 17.7 16.8 9.0 44.6 0.1 0.0 0.0 26.7 0.2 0.2 0.7 2.7 93.4 14.6 6.2 19.7 0.0 13.3 28.1 22.8 6.2 1.0 9.3 19.0 0.1 24.1 63.0 2.9 1.8 0.1 0.0 24.6 1.3 0.4 10.8 9.0 5.5 0.3 0.4 0.0 1.1 3.7 0.1 109.1 15.2 0.0 0.1 15.2 12.5 38.7 104.4 18.5 12.3 10.9 12.6 6.7 45.8 25.4 0.3 0.5 0.2 25.8 0.4 6.6 4.5 7.7 0.4 3.6 0.1 0.6 1.0 0.1 0.1 0.1 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.6 0.2 0.3 0.2 0.0 0.0 0.1 0.2 7.0 8.7 6.6 10.8 8.9 7.1 10.4 6.8 9.3 9.7 7.3 17.7 0.2 141.1 79.0 2.6 1.0 323.4 172.7 110.6 132.6 16.9 58.6 28.2 29.8 161.5 106.6 103.0 27.1 0.8 0.3 238.4 5.9 130.0 5.3 118.9 8.3 4.8 80.8 9.9 60.4 93.7 0.2 8.6 94.3 128.9 5.7 1.1 47.8 127.7 0.6 0.0 43.0 107.5 81.4 22.9 13.1 7.7 2.1 3.3 23.2 40.3 0.7 13.4 0.0 78.9 161.4 93.4 155.3 0.0 1.6 125.1 263.0 4.0 85.6 11.2 6.6 0.2 5.3 6.4 24.5 117.0 343.8 0.7 4.3 0.5 107.0 202.7 CXCL1 "FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1" ENSG00000163739 "C-X-C motif chemokine ligand 1" P09341 4 73869393-73871308 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 102.2;lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16674.3;Club cells: 7384.0;Ionocytes: 4146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 243 "neutrophil: 47.3" "Lineage enriched" "Detected in single" 243 "granulocytes: 47.3" "Group enriched" "Detected in many" 6 "BJ hTERT+: 748.4;EFO-21: 1906.7;RPTEC TERT1: 682.0" "Secreted to blood" NA NA 384000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "prognostic favorable (7.83e-4)" "prognostic unfavorable (7.23e-4)" "unprognostic (5.24e-3)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (5.45e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.17e-1)" "unprognostic (5.30e-2)" "unprognostic (7.41e-2)" "unprognostic (9.41e-2)" 38.0 6.2 4.3 49.0 4.9 41.6 3.8 3.6 8.1 102.2 4.8 14.6 10.6 2.3 0.1 38.7 14.9 25.7 28.3 3.5 3.7 18.7 10.2 45.2 2.4 4.0 3.7 2.4 25.7 0.4 2.0 5.1 4.3 18.7 16.0 0.4 23.7 9.5 1.7 2.2 26.9 3.0 4.1 196.6 9.1 0.2 5.4 2.9 1.9 1.9 23.6 75.5 25.5 4.2 3.7 4.4 0.0 0.0 4.4 11.7 0.0 20.6 748.4 17.7 18.8 0.2 13.4 0.0 1906.7 1.3 72.5 38.6 0.0 3.5 94.2 2.8 0.0 0.0 1.3 0.0 4.4 0.0 0.0 9.7 1.3 133.2 10.6 1.4 144.7 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 7.7 5.4 0.0 0.0 0.0 682.0 16.7 0.1 0.0 1.5 0.3 40.4 2.0 0.5 1.9 173.9 0.0 6.6 37.8 1.5 0.0 1.6 3.7 1.9 0.1 26.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 4.3 4.9 3.6 8.1 3.5 3.7 4.0 3.7 4.3 4.1 5.4 4.2 7.9 44.8 273.3 0.0 2.9 126.6 991.1 16674.3 131.5 0.0 61.3 42.9 4.1 413.2 7384.0 5.5 0.0 0.3 1.4 40.3 0.0 1073.2 0.0 152.2 21.5 106.7 635.7 0.0 0.0 42.5 0.7 449.0 20.9 199.0 15.8 1.4 3.9 2.1 26.7 0.0 0.0 31.1 4146.2 10.4 467.3 0.0 0.0 110.8 124.5 0.0 56.9 0.0 0.0 0.0 0.0 232.8 7.6 0.0 0.1 2062.0 19.6 3.1 1219.7 0.0 0.0 152.9 217.7 0.4 0.2 48.7 105.1 0.4 27.8 0.1 66.0 1251.3 CXCL10 "C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10" ENSG00000169245 "C-X-C motif chemokine ligand 10" P02778 4 76021118-76023497 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.7;Glandular and luminal cells: 23.5;Kupffer cells: 41.1;Langerhans cells: 21.4;Macrophages: 45.7;Plasma cells: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 21.5;intermediate monocyte: 52.4;non-classical monocyte: 36.9" "Lineage enriched" "Detected in many" 15 "monocytes: 52.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.1;BJ hTERT+ SV40 Large T+: 2.2;BJ hTERT+ SV40 Large T+ RasG12V: 2.2;GAMG: 5.1;RPMI-8226: 4.3;RT4: 2.4;THP-1: 3.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 253000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.94e-1)" "unprognostic (5.32e-2)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (7.59e-2)" "prognostic favorable (1.12e-5)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-2)" 4.0 5.9 1.4 95.5 1.5 1.2 20.7 0.9 2.6 13.2 1.2 10.7 11.2 7.1 0.7 8.0 4.1 10.6 4.4 1.2 1.0 7.8 29.0 35.1 68.0 7.4 1.2 3.0 0.9 17.1 2.1 10.3 10.8 43.9 15.9 0.4 20.1 1.8 1.2 2.0 11.2 15.8 3.4 20.3 19.2 3.0 2.6 35.2 3.7 1.1 17.3 45.1 3.7 1.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.1 2.2 2.2 0.2 0.1 2.0 0.2 0.0 5.1 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.3 0.1 2.4 0.0 0.0 0.0 0.4 1.3 0.0 0.1 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.6 0.0 0.0 21.5 0.0 0.0 52.4 0.0 1.4 0.3 0.0 3.5 0.1 0.0 0.0 1.1 0.0 36.9 0.0 0.0 7.6 1.4 1.5 0.9 2.6 1.2 1.0 7.4 1.2 10.8 3.4 2.6 1.5 3.8 0.0 2.2 0.0 2.2 0.9 9.4 52.7 0.6 0.0 2.6 7.0 0.3 1.5 2.8 0.0 0.0 0.1 0.0 2.7 0.0 5.9 2.6 12.5 10.9 8.0 0.0 0.0 0.0 0.0 0.0 6.9 3.1 23.5 1.3 0.0 0.0 0.1 17.3 0.0 0.0 1.0 10.2 41.1 21.4 4.0 0.3 45.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 11.4 6.4 2.6 1.3 0.0 0.0 1.3 12.4 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.9 1.4 CXCL11 "b-R1, H174, I-TAC, IP-9, SCYB11, SCYB9B" ENSG00000169248 "C-X-C motif chemokine ligand 11" O14625 4 76033682-76041415 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Basal prostatic cells: 2.6;Basal respiratory cells: 2.9;Distal enterocytes: 2.7;Exocrine glandular cells: 3.6;Macrophages: 4.3;Prostatic glandular cells: 3.7;Proximal enterocytes: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 3.4;BJ hTERT+ SV40 Large T+: 5.1;BJ hTERT+ SV40 Large T+ RasG12V: 5.3;GAMG: 1.4" "Region enhanced" "Detected in single" "spinal cord: 1.2" CAB009921 Uncertain "Secreted to blood" NA NA 187000 "Cluster 3: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB009921: AB_2088137" "unprognostic (2.00e-1)" "unprognostic (3.62e-1)" "unprognostic (6.94e-3)" "unprognostic (1.87e-2)" "unprognostic (9.95e-2)" "unprognostic (5.85e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.31e-7)" "prognostic unfavorable (8.18e-5)" "unprognostic (2.90e-1)" "prognostic unfavorable (3.29e-6)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (4.48e-2)" "unprognostic (5.32e-2)" 1.6 0.4 1.5 11.1 1.3 0.3 3.7 1.1 3.5 2.5 1.0 1.7 0.8 1.5 0.2 1.0 1.6 1.2 1.2 1.2 1.2 1.3 2.4 6.0 11.9 2.3 1.4 0.5 8.9 0.1 0.3 3.6 2.2 5.2 4.3 0.0 3.1 0.3 0.3 0.3 1.2 1.7 1.6 5.8 6.3 0.9 2.0 6.3 1.2 0.0 1.4 4.6 0.6 1.3 0.8 0.2 0.0 0.0 0.0 0.1 0.0 0.0 3.4 5.1 5.3 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 1.1 3.5 1.2 1.2 2.3 1.4 2.2 1.6 2.0 1.3 0.5 3.2 0.0 0.0 0.2 0.1 2.6 2.9 0.0 0.0 0.2 0.3 0.2 1.5 0.2 0.0 0.0 0.0 0.0 2.7 0.0 2.0 0.0 0.7 0.9 2.2 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.6 0.0 0.0 0.4 0.2 1.8 0.0 0.0 0.1 0.0 2.1 0.3 0.0 0.0 4.3 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.7 2.8 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.2 0.0 1.2 1.4 CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 347.2;Distal tubular cells: 172.1;Fibroblasts: 566.4;Kupffer cells: 191.8;Smooth muscle cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 509.6;BJ hTERT+: 303.5;BJ hTERT+ SV40 Large T+: 294.9;BJ hTERT+ SV40 Large T+ RasG12V: 441.2;fHDF/TERT166: 501.8;HSkMC: 1293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" 366.8 82.6 19.4 143.8 20.2 35.1 237.4 19.1 28.1 268.4 24.5 124.3 53.6 360.7 54.3 138.5 122.1 263.3 190.3 19.4 18.6 124.8 252.8 71.0 215.8 22.3 21.1 112.3 131.2 126.7 21.3 8.5 19.1 47.8 115.5 2.1 116.3 66.2 158.9 99.4 96.5 343.5 19.9 356.6 45.4 19.4 21.0 142.6 103.4 181.3 119.7 107.0 174.3 17.7 0.0 0.0 0.4 0.6 509.6 78.9 0.4 187.7 303.5 294.9 441.2 0.0 0.1 0.2 1.9 501.8 0.0 0.1 0.8 0.2 97.1 187.2 2.4 0.0 0.0 0.0 172.8 0.4 0.9 1293.8 0.0 63.8 0.1 0.0 0.2 0.1 0.1 0.0 1.0 0.4 0.7 0.6 32.2 0.0 0.6 0.8 0.3 224.3 0.2 0.0 0.6 0.6 0.3 0.7 0.0 63.6 272.2 0.4 0.4 0.4 0.5 205.0 0.2 0.2 0.1 0.1 0.6 0.3 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 20.2 19.1 28.1 19.4 18.6 22.3 21.1 19.1 19.9 21.0 17.7 347.2 0.0 1.1 1.3 1.4 76.3 0.3 0.0 9.6 1.5 8.1 14.0 25.0 10.0 0.6 5.5 0.0 0.3 2.1 0.0 172.1 0.8 2.2 1.7 46.8 134.1 0.0 0.0 0.6 20.5 0.3 566.4 1.5 1.0 0.0 0.4 55.6 2.5 2.6 0.0 6.6 3.9 0.0 191.8 110.1 3.7 70.2 27.9 135.2 74.0 0.0 1.9 0.0 12.1 0.1 3.0 0.0 8.6 1.0 1.0 0.1 25.5 0.0 0.8 85.5 43.7 146.1 1.8 5.9 6.3 62.7 0.7 9.6 33.2 0.5 0.5 CXCL13 "ANGIE, ANGIE2, BCA-1, BLC, BLR1L, SCYB13" ENSG00000156234 "C-X-C motif chemokine ligand 13" O43927 4 77511753-77611834 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 523.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 242.2;Breast myoepithelial cells: 72.4;Endometrial stromal cells: 101.0;monocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA052613 Uncertain "Secreted to blood" NA NA 93700 "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" "HPA052613: AB_2681885" "unprognostic (5.25e-3)" "unprognostic (1.19e-2)" "prognostic favorable (9.12e-4)" "prognostic favorable (5.52e-4)" "unprognostic (1.53e-2)" "unprognostic (1.17e-3)" "unprognostic (1.49e-1)" "unprognostic (6.41e-3)" "unprognostic (9.82e-3)" "prognostic favorable (5.41e-4)" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (1.16e-10)" "unprognostic (2.04e-2)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (6.68e-3)" 2.6 0.4 0.1 127.7 0.4 0.1 15.4 0.4 0.3 1.4 0.1 13.3 1.9 3.6 1.6 2.4 0.8 5.8 1.2 0.1 0.1 0.6 28.5 2.9 523.1 1.1 0.1 0.7 0.3 0.2 3.1 0.6 0.1 27.3 16.5 0.2 8.5 1.4 0.0 0.6 68.5 1.2 0.4 338.6 34.9 1.5 0.1 16.2 2.4 0.0 441.3 30.6 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.1 0.1 1.1 0.1 0.1 0.4 0.1 0.2 0.9 0.0 0.5 1.3 0.3 0.1 15.8 3.9 0.0 0.0 242.2 72.4 0.0 1.5 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.6 101.0 1.7 0.0 10.7 1.9 0.2 0.3 6.3 0.5 1.8 1.3 0.0 3.6 21.3 10.2 0.0 3.9 0.0 0.0 3.4 0.0 0.0 0.0 0.9 0.0 1.9 38.8 0.0 0.0 1.0 0.4 0.1 0.0 0.0 0.2 3.8 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.3 7.8 0.0 0.1 4.5 CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3435.4;Basal squamous epithelial cells: 3284.9;Breast myoepithelial cells: 1544.3;Fibroblasts: 2220.8;Glandular and luminal cells: 1201.1;Proximal tubular cells: 3662.8;Suprabasal keratinocytes: 2115.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HAP1: 61.6;hTCEpi: 79.9;RPTEC TERT1: 222.2;SuSa: 115.2;U-2 OS: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 33: Fibroblasts - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" 366.1 5.2 77.6 76.2 84.5 0.6 229.1 70.6 102.7 166.3 74.8 152.4 214.0 6.9 66.6 92.9 32.9 19.8 14.0 83.7 73.8 345.6 58.5 7.4 90.7 72.4 91.0 5.5 11.6 1.9 122.0 170.7 72.4 10.1 181.3 17.5 293.5 17.6 81.1 780.3 247.0 6.3 68.7 87.5 107.3 3.7 90.2 26.6 55.2 36.5 128.5 76.6 96.3 77.9 0.0 0.0 2.7 0.0 0.2 0.2 0.7 2.9 0.8 0.2 0.0 0.0 9.1 0.0 2.7 0.1 3.8 0.2 61.6 1.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 79.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 4.0 0.0 0.0 0.2 0.0 1.1 222.2 0.0 1.1 0.7 0.2 0.2 0.0 115.2 0.1 0.0 0.0 0.1 84.9 0.4 0.1 0.3 0.0 0.0 1.4 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 77.6 84.5 70.6 102.7 83.7 73.8 72.4 91.0 72.4 68.7 90.2 77.9 123.8 0.0 1.1 32.7 13.1 3435.4 14.4 276.9 3284.9 245.7 47.5 1544.3 4.1 0.0 5.1 283.3 0.0 35.9 6.1 0.0 563.4 0.0 0.8 45.0 140.8 45.9 0.0 0.0 1.0 0.0 25.4 2220.8 0.5 1201.1 0.0 0.0 43.5 0.2 63.6 6.7 150.8 0.0 240.1 0.9 887.9 1.3 20.8 35.3 439.4 8.4 0.0 6.7 0.0 4.5 4.2 0.1 0.0 0.4 13.3 10.6 0.0 3662.8 2.1 19.0 0.0 889.8 99.2 0.4 5.2 69.3 2115.0 77.2 43.4 0.3 0.1 9.3 CXCL16 "CXCLG16, SR-PSOX, SRPSOX" ENSG00000161921 "C-X-C motif chemokine ligand 16" Q9H2A7 17 4733533-4739928 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 4051.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 63.3;intermediate monocyte: 107.5;myeloid DC: 38.2;neutrophil: 103.2;non-classical monocyte: 141.6" "Group enriched" "Detected in many" 7 "dendritic cells: 38.2;granulocytes: 103.2;monocytes: 141.6" "Cell line enhanced" "Detected in many" "A-431: 86.5;CACO-2: 63.5;CAPAN-2: 58.4;HaCaT: 97.9;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053253, HPA066315" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1100000 6800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "HPA053253: AB_2682091, HPA066315: AB_2685657" "unprognostic (4.64e-3)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (4.05e-1)" "unprognostic (4.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.78e-2)" "unprognostic (4.74e-2)" "unprognostic (2.37e-2)" "unprognostic (2.48e-2)" "unprognostic (2.60e-1)" 27.6 18.1 18.7 56.0 19.4 70.4 29.3 20.0 30.7 19.8 20.8 21.9 45.7 11.7 15.3 24.6 24.0 54.0 7.8 17.4 23.0 19.6 52.6 106.0 23.7 32.5 22.7 10.5 20.8 61.8 14.4 31.1 27.9 16.3 25.8 10.2 47.1 14.4 2.6 21.8 39.3 17.6 25.2 43.8 41.2 112.6 28.7 12.5 10.5 3.3 17.9 60.6 14.3 34.2 86.5 12.4 0.4 44.7 0.7 3.1 11.5 1.1 8.9 11.2 15.6 63.5 58.4 0.1 10.0 1.5 8.6 97.9 20.0 14.1 5.3 8.9 14.8 0.4 1.7 29.5 8.5 0.1 15.8 0.7 26.6 5.9 1.3 7.4 3.1 0.9 0.4 0.7 0.8 20.9 0.3 1.8 0.4 42.1 7.2 1.2 0.0 13.2 30.4 15.8 0.4 1.4 17.6 11.3 5.5 2.3 57.4 1.4 0.4 1.5 6.8 2.2 5.3 3.0 3.9 0.1 0.5 2.9 2.4 0.6 63.3 16.7 0.5 107.5 0.7 9.5 1.1 0.8 38.2 13.0 0.8 1.2 103.2 0.6 141.6 16.0 0.1 29.2 18.7 19.4 20.0 30.7 17.4 23.0 32.5 22.7 27.9 25.2 28.7 34.2 9.7 73.7 46.6 1.6 17.4 70.1 130.4 133.4 40.5 2.6 64.8 50.3 0.8 58.6 132.4 40.5 2.1 3.4 11.1 28.1 3.9 151.0 795.4 22.1 4.1 25.4 30.9 2.7 0.1 145.9 2.5 14.2 36.7 32.7 74.1 2.3 132.1 9.0 196.4 3.3 0.3 32.2 44.7 231.6 406.3 4051.5 24.5 270.6 26.6 15.0 556.1 13.2 1.0 5.0 1.2 188.1 44.5 30.1 2.2 277.2 51.3 17.4 62.4 1.3 19.7 3.4 14.4 22.7 11.5 33.7 76.4 2.9 11.7 1.6 23.7 272.7 CXCL17 "Dcip1, DMC, UNQ473, VCC1" ENSG00000189377 "C-X-C motif chemokine ligand 17" Q6UXB2 19 42428278-42442946 "Predicted secreted proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 120.5;lung: 149.0;salivary gland: 145.6;stomach 1: 358.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 513.8;Basal respiratory cells: 988.1;Club cells: 1743.3;Respiratory ciliated cells: 383.0;Urothelial cells: 1584.1" "Cancer enhanced" "Detected in many" "cervical cancer: 170.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "OE19: 8.7;RT4: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.74e-1)" "unprognostic (3.96e-2)" "unprognostic (2.78e-1)" "unprognostic (1.03e-2)" "unprognostic (4.46e-3)" "unprognostic (3.77e-1)" "prognostic favorable (4.92e-5)" "unprognostic (6.68e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.70e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-1)" "unprognostic (1.88e-1)" "unprognostic (8.13e-3)" "unprognostic (2.29e-1)" 0.2 0.1 0.1 0.1 0.0 0.0 2.3 0.2 0.1 19.2 0.0 0.8 0.7 0.9 22.3 120.5 27.1 6.5 0.1 0.1 0.0 0.2 0.1 149.0 0.0 0.0 0.0 0.3 42.9 0.0 0.6 0.0 0.0 8.2 0.0 0.0 145.6 0.4 0.0 0.3 0.0 0.1 0.0 0.2 358.6 0.1 0.0 1.1 0.5 0.0 24.2 47.6 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 8.7 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 35.3 513.8 0.3 0.1 0.0 225.5 988.1 1.2 0.4 21.5 10.3 0.0 4.3 1743.3 5.5 0.0 0.0 0.2 0.2 0.0 8.7 0.4 3.0 0.6 3.5 0.0 0.0 1.5 187.4 0.0 4.3 302.2 8.4 16.4 0.1 0.0 0.0 0.0 0.0 1.2 0.0 227.9 0.0 0.0 1.5 0.0 3.9 0.0 0.0 2.6 0.2 0.0 0.5 0.5 339.6 0.0 0.0 0.5 221.2 0.0 0.2 383.0 0.6 0.0 0.0 67.6 0.1 0.6 91.6 0.0 0.0 2.4 0.0 0.2 1584.1 CXCL2 "CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2" ENSG00000081041 "C-X-C motif chemokine ligand 2" P19875 4 74097040-74099196 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 509.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1668.3;Basal respiratory cells: 3166.0;Basal squamous epithelial cells: 1671.5;Langerhans cells: 2390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 1.1;non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 10 "monocytes: 1.1" "Cell line enriched" "Detected in many" 8 "GAMG: 430.9" "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "prognostic favorable (5.93e-5)" "prognostic unfavorable (1.41e-4)" "unprognostic (5.28e-3)" "unprognostic (1.36e-1)" "unprognostic (2.64e-3)" "unprognostic (1.27e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (6.72e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.07e-6)" "unprognostic (1.05e-2)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" 95.6 12.5 4.7 28.2 3.7 88.7 39.6 3.3 6.1 61.0 4.0 9.6 3.5 15.1 0.3 12.2 17.4 52.2 49.8 4.3 10.1 14.7 509.9 87.6 12.6 5.8 4.7 9.1 88.3 2.7 7.2 3.8 4.0 13.4 21.1 1.7 20.7 10.0 21.5 3.2 11.0 14.8 4.4 7.8 26.6 1.3 9.7 3.8 6.6 35.6 1.3 82.1 3.4 4.2 1.3 3.8 0.2 0.0 1.3 4.4 0.1 4.2 52.9 2.1 6.2 0.3 8.0 0.0 7.0 0.3 430.9 0.1 0.3 11.2 8.4 0.1 0.2 3.3 5.0 0.0 35.6 1.4 0.0 4.0 38.5 27.2 37.0 1.4 4.6 0.1 0.1 0.0 1.1 0.0 0.5 0.5 0.0 4.6 1.1 0.0 0.0 0.0 26.2 0.0 0.0 0.1 2.5 0.4 1.1 0.4 0.1 0.1 7.1 1.9 0.7 7.7 4.0 0.1 0.1 0.1 30.8 8.9 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 4.7 3.7 3.3 6.1 4.3 10.1 5.8 4.7 4.0 4.4 9.7 4.2 620.7 477.5 1668.3 1.0 15.0 415.5 336.3 3166.0 1671.5 0.0 762.9 283.3 22.9 469.0 957.6 9.2 0.0 3.3 17.9 91.4 0.0 858.1 1.1 489.8 149.1 677.8 132.1 34.7 0.0 603.6 3.1 488.7 206.9 1223.1 85.2 0.1 365.1 325.8 117.3 0.0 0.0 131.6 498.5 291.4 2390.3 0.8 15.8 926.0 277.5 0.0 50.7 0.6 0.0 0.0 0.0 282.5 14.6 0.0 35.3 342.6 57.8 1.1 194.1 0.3 72.3 131.8 288.7 1.1 5.0 440.3 227.7 2.2 36.3 0.6 128.5 119.1 CXCL3 "CINC-2b, GRO3, GROg, MIP-2b, SCYB3" ENSG00000163734 "C-X-C motif chemokine ligand 3" P19876 4 74036589-74038807 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 20.8;cervix: 20.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2244.7;Club cells: 738.5;Ionocytes: 724.2;Langerhans cells: 2366.2;Macrophages: 718.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.4;stomach cancer: 18.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 48.5;hTEC/SVTERT24-B: 75.0;RPTEC TERT1: 43.8" "Secreted to blood" NA NA 28700 "Cluster 82: Adipose tissue - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.12e-3)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.08e-3)" "unprognostic (6.97e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-4)" "unprognostic (2.45e-2)" "unprognostic (2.24e-1)" "unprognostic (2.68e-1)" "unprognostic (9.69e-2)" "unprognostic (1.81e-1)" "unprognostic (2.89e-6)" "unprognostic (2.61e-3)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (1.20e-1)" 20.8 1.0 0.7 14.4 0.4 15.8 1.6 0.4 2.2 20.7 0.6 4.1 0.7 0.7 0.0 1.0 1.3 6.9 6.4 0.5 0.6 1.4 3.9 15.8 0.7 0.6 0.6 1.0 1.8 0.1 0.5 0.6 0.5 1.7 9.2 0.1 5.9 0.3 0.5 0.5 2.5 1.6 0.5 2.0 8.9 0.3 2.7 2.0 0.7 1.0 0.7 15.9 0.6 0.7 0.5 3.7 1.5 0.0 0.8 1.4 0.0 5.3 48.5 1.3 2.9 0.1 5.9 0.0 5.2 0.0 17.6 0.2 0.3 1.7 10.5 0.0 0.0 4.1 0.6 0.0 5.7 0.5 0.0 1.1 1.2 75.0 7.3 1.2 1.1 0.8 0.9 0.0 2.1 0.0 1.1 0.2 0.7 7.0 1.5 0.1 1.7 0.0 43.8 1.3 0.0 0.0 0.5 0.0 1.1 0.7 0.2 0.0 2.0 10.5 0.6 5.3 13.7 0.0 0.0 0.0 11.9 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.7 0.4 0.4 2.2 0.5 0.6 0.6 0.6 0.5 0.5 2.7 0.7 34.2 99.3 244.9 1.6 10.1 228.4 205.6 2244.7 340.9 0.0 123.0 79.9 14.8 125.8 738.5 5.5 0.0 0.7 5.9 137.1 0.0 217.6 1.7 103.4 24.3 113.7 52.9 0.0 0.0 96.7 1.1 161.0 408.7 157.2 27.3 0.2 15.7 1.4 72.2 0.0 0.0 168.3 724.2 162.9 2366.2 5.6 14.0 718.0 188.5 1.0 28.1 0.0 0.0 0.0 0.0 186.1 33.5 0.4 5.1 225.9 95.7 0.2 144.2 0.0 39.5 78.5 92.6 1.7 8.3 50.3 148.6 8.1 14.0 0.1 197.5 79.7 CXCL5 "ENA-78, SCYB5" ENSG00000163735 "C-X-C motif chemokine ligand 5" P42830 4 73995642-73998677 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 35.9;salivary gland: 50.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 64.6;Ductal cells: 94.0;Macrophages: 222.6;Pancreatic endocrine cells: 245.4" "Group enriched" "Detected in many" 4 "pancreatic cancer: 56.2;stomach cancer: 74.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 191.9;EFO-21: 157.0;HSkMC: 111.4;hTEC/SVTERT24-B: 81.6;RPTEC TERT1: 603.6" HPA065474 Approved Approved Vesicles "Secreted to blood" NA NA 1110000 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA065474: AB_2685494" "unprognostic (5.56e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.43e-2)" "unprognostic (2.04e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.06e-2)" "unprognostic (3.04e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (7.99e-2)" "prognostic unfavorable (2.45e-5)" "unprognostic (3.72e-1)" "unprognostic (3.07e-1)" "unprognostic (2.72e-2)" "unprognostic (9.30e-2)" 2.1 0.2 1.5 35.9 0.9 1.2 3.2 0.6 8.8 7.7 0.4 0.7 0.8 0.2 0.0 0.1 0.2 4.8 0.6 0.8 2.6 0.2 1.3 10.0 6.3 1.4 2.1 0.0 0.5 0.0 0.1 0.2 3.1 1.3 0.3 0.0 50.2 0.5 0.1 0.0 2.1 0.2 1.1 2.1 8.5 0.4 5.7 0.6 0.0 0.2 0.6 8.4 0.0 0.7 0.1 191.9 0.7 0.0 0.3 6.9 0.0 3.5 2.9 1.5 3.0 0.6 1.6 0.0 157.0 0.1 34.0 0.4 0.0 0.0 17.6 0.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 111.4 0.0 81.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 603.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.5 0.0 1.0 0.0 0.1 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.0 1.5 0.9 0.6 8.8 0.8 2.6 1.4 2.1 3.1 1.1 5.7 0.7 0.2 3.2 0.0 0.0 0.0 0.9 0.7 64.6 0.0 0.0 8.0 4.4 1.2 15.7 33.2 0.0 0.0 0.0 0.1 1.3 0.0 94.0 0.7 0.7 0.1 1.8 0.0 0.0 0.3 1.4 0.1 3.6 15.3 1.2 0.0 0.0 0.7 0.0 0.5 0.0 0.3 0.7 4.1 0.3 30.4 0.3 0.0 222.6 0.0 1.0 2.1 0.0 0.0 0.0 0.1 245.4 0.0 0.0 0.3 3.1 0.0 0.1 4.3 0.0 0.0 0.6 4.0 0.1 0.6 0.0 0.3 0.0 0.3 0.0 1.1 2.0 CXCL6 "CKA-3, GCP-2, SCYB6" ENSG00000124875 "C-X-C motif chemokine ligand 6" P80162 4 73836640-73849064 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 36.0;lymphoid tissue: 100.8;urinary bladder: 26.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 241.2;Basal respiratory cells: 509.4;Cholangiocytes: 317.4;Club cells: 361.3;Ductal cells: 1120.6;Prostatic glandular cells: 245.5;Urothelial cells: 328.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "cerebral cortex: 5.3" "Immune cell enriched" "Detected in single" 104 "neutrophil: 10.4" "Lineage enriched" "Detected in single" 104 "granulocytes: 10.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 53.2;EFO-21: 136.5;hTEC/SVTERT24-B: 28.8;HUVEC TERT2: 84.5;RPTEC TERT1: 98.4" "Region enhanced" "Detected in many" "basal ganglia: 9.6" "Not detected" "Not detected" "Secreted to blood" NA NA 108000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (4.35e-4)" "unprognostic (4.47e-2)" "unprognostic (6.09e-2)" "unprognostic (4.60e-2)" "unprognostic (1.98e-2)" "unprognostic (1.17e-1)" "unprognostic (3.49e-3)" "unprognostic (2.62e-1)" "unprognostic (2.05e-1)" "unprognostic (2.02e-2)" "unprognostic (3.75e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.47e-1)" "unprognostic (4.88e-1)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" 6.0 0.1 0.5 14.1 0.8 2.1 0.6 0.2 5.3 4.6 2.7 0.9 8.0 0.0 0.1 2.5 2.4 36.0 3.2 0.3 0.6 3.7 6.6 2.7 0.3 0.4 0.4 0.1 5.3 0.0 0.2 0.1 0.6 3.5 0.6 0.0 3.8 10.8 0.0 0.0 10.3 0.3 0.2 100.8 1.2 0.3 0.9 2.6 0.0 0.3 2.8 26.5 5.6 0.3 0.0 0.0 0.5 0.0 4.4 16.6 0.0 3.3 53.2 0.4 0.7 0.0 0.0 0.0 136.5 0.2 5.3 11.8 0.0 0.0 8.1 1.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 10.1 0.3 28.8 0.0 0.4 84.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 3.9 0.0 0.0 0.0 98.4 1.9 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.0 1.4 0.9 0.5 0.0 0.6 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.2 5.3 0.3 0.6 0.4 0.4 0.6 0.2 0.9 0.3 0.0 3.2 2.0 0.0 0.1 0.4 241.2 509.4 0.0 0.0 2.9 1.3 0.2 317.4 361.3 0.0 0.0 0.0 0.0 0.2 0.0 1120.6 0.0 0.7 0.1 2.0 78.1 0.0 0.0 3.9 0.0 13.2 0.0 1.3 0.0 0.3 0.0 0.6 0.2 0.0 0.0 0.2 97.6 0.3 0.8 0.1 0.0 1.1 0.0 0.0 7.8 0.0 0.0 0.0 0.0 43.5 0.0 0.0 0.0 245.5 0.0 0.3 75.7 0.0 0.0 1.5 18.4 0.0 1.2 0.3 0.1 0.0 0.1 0.0 0.1 328.4 CXCL8 "3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1" ENSG00000169429 "C-X-C motif chemokine ligand 8" P10145 4 73740541-73743716 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3301.3" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13262.1;Macrophages: 3685.4;Prostatic glandular cells: 8869.1;Urothelial cells: 13149.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 9 "cerebral cortex: 136.1" "Immune cell enriched" "Detected in some" 451 "neutrophil: 483.0" "Lineage enriched" "Detected in single" 788 "granulocytes: 483.0" "Group enriched" "Detected in many" 5 "BJ hTERT+: 4072.6;GAMG: 1080.2" "Not detected" "Not detected" HPA057179 Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 7260 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA057179: AB_2683362" "unprognostic (3.42e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (3.91e-3)" "unprognostic (8.49e-2)" "unprognostic (3.29e-2)" "unprognostic (3.03e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.37e-3)" "unprognostic (3.19e-1)" "unprognostic (4.46e-1)" "unprognostic (7.19e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.13e-6)" "unprognostic (4.73e-2)" "unprognostic (8.57e-2)" "unprognostic (1.64e-2)" "unprognostic (6.15e-2)" 67.9 13.5 1.8 209.9 2.8 3301.3 3.6 1.7 136.1 54.5 7.6 10.6 3.6 41.0 0.2 3.7 8.9 177.2 33.8 1.7 1.6 10.8 77.7 91.2 1.2 2.1 1.6 6.0 16.1 1.8 3.2 41.1 15.1 9.6 7.3 0.9 25.4 1.5 1.3 3.2 4.9 12.7 1.9 10.3 8.8 0.7 4.9 15.2 3.4 8.1 8.7 456.7 4.0 1.9 2.7 1.4 0.0 0.1 3.9 19.4 0.2 25.7 4072.6 35.9 117.0 0.2 13.0 0.2 547.6 1.3 1080.2 48.2 0.0 1.0 562.3 1.8 0.2 0.9 0.4 6.5 6.8 41.0 2.5 12.4 1.7 119.0 2.9 12.9 124.9 0.0 1.4 0.8 0.7 0.0 0.0 55.7 0.0 14.7 20.3 0.3 0.5 0.9 317.3 17.2 0.1 0.0 1.9 0.1 61.1 0.8 0.1 5.6 308.3 56.8 5.1 15.1 55.0 0.4 0.7 1.7 252.5 30.9 88.2 1.0 0.6 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 483.0 0.0 0.0 0.0 0.0 0.1 1.8 2.8 1.7 136.1 1.7 1.6 2.1 1.6 15.1 1.9 4.9 1.9 28.6 51.3 254.1 0.0 26.4 0.0 13262.1 0.0 164.4 0.5 40.2 15.4 23.8 127.2 426.5 0.0 0.0 4.3 17.7 14.4 0.0 1695.0 3.2 717.6 257.1 712.2 19.1 8.0 0.0 260.7 5.2 1475.1 54.0 1708.7 51.2 0.5 15.7 3.6 367.1 0.0 0.0 26.4 0.0 543.0 0.0 1.9 0.6 3685.4 0.0 0.0 1178.5 0.5 0.0 0.0 0.0 584.9 0.3 0.4 27.3 8869.1 0.9 1.0 178.6 1.1 39.5 44.3 263.0 0.3 2.5 124.9 0.0 21.3 138.8 0.0 18.5 13149.4 CXCL9 "CMK, crg-10, Humig, MIG, SCYB9" ENSG00000138755 "C-X-C motif chemokine ligand 9" Q07325 4 76001275-76007509 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 309.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.0;Hofbauer cells: 6.2;Kupffer cells: 10.3;Macrophages: 12.6;Spermatogonia: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "RPMI-8226: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 902000 "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "prognostic favorable (6.36e-4)" "unprognostic (6.86e-3)" "unprognostic (1.25e-2)" "prognostic favorable (2.07e-4)" "unprognostic (2.97e-1)" "unprognostic (3.78e-3)" "unprognostic (8.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.46e-2)" "prognostic favorable (8.06e-4)" "unprognostic (2.18e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.15e-6)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (1.57e-2)" "unprognostic (6.54e-2)" 5.5 2.0 0.1 65.1 0.2 0.2 17.5 0.1 0.6 4.9 0.3 10.2 3.0 4.8 0.7 5.3 2.8 8.5 5.9 0.1 0.1 8.7 19.1 31.8 309.9 1.8 0.2 3.8 1.4 1.5 1.0 1.7 1.6 3.7 25.3 0.0 19.0 0.7 1.5 2.9 6.0 3.2 0.3 31.2 17.5 6.0 0.2 32.8 7.1 2.5 30.6 11.1 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 1.8 0.2 1.6 0.3 0.2 0.3 3.4 0.0 1.7 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.2 0.4 0.0 0.2 1.3 0.1 1.1 2.1 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 5.0 1.8 6.2 0.0 0.0 0.0 0.0 10.3 3.6 1.3 0.6 12.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 3.5 1.7 8.0 0.0 0.3 0.1 0.5 0.0 0.1 0.4 CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" 19.0 21.7 17.4 6.1 17.3 4.3 18.2 17.4 20.1 15.9 14.2 10.7 15.2 15.6 28.5 10.9 18.7 16.3 14.0 16.7 19.6 25.5 29.0 9.7 9.3 18.1 17.6 20.8 19.7 30.9 24.1 10.8 17.8 13.5 7.4 9.2 20.0 17.6 16.2 14.4 12.1 8.4 17.6 9.6 16.0 29.3 17.9 10.2 22.7 14.9 7.2 12.9 11.7 18.7 16.2 21.6 11.8 12.7 74.7 22.5 5.2 15.7 31.5 11.0 10.9 6.3 10.3 5.3 13.6 17.4 9.2 22.5 4.9 7.1 4.4 17.9 25.7 5.0 13.5 10.5 13.7 2.1 9.5 28.8 17.0 6.2 11.7 22.3 20.1 11.5 5.1 31.2 8.3 20.6 7.8 3.4 4.3 13.7 11.5 9.2 10.6 12.5 25.1 8.5 9.3 8.1 17.2 9.9 23.5 13.1 25.6 3.2 28.5 15.7 4.0 14.5 8.0 5.8 4.9 3.9 19.9 4.5 6.2 0.6 10.8 13.6 5.9 9.2 6.7 8.1 9.3 7.4 10.5 7.1 8.6 8.0 9.5 5.5 8.7 11.3 11.2 8.2 17.4 17.3 17.4 20.1 16.7 19.6 18.1 17.6 17.8 17.6 17.9 18.7 57.4 12.8 10.3 9.1 17.2 53.7 18.4 36.0 12.5 26.9 35.4 36.7 9.8 45.8 21.8 31.3 58.4 55.7 11.4 18.5 52.8 34.3 28.5 36.6 20.0 34.4 13.8 33.3 7.6 27.0 29.1 23.8 19.4 23.4 11.4 22.3 41.0 32.9 21.4 40.4 10.4 16.0 36.7 24.0 23.8 30.6 28.9 17.3 14.2 4.7 15.4 37.6 15.5 8.5 10.0 26.9 18.9 28.6 17.6 8.3 39.7 55.7 38.5 30.4 0.0 15.2 20.1 130.3 29.2 9.5 42.9 38.6 15.8 39.3 16.6 15.8 CYTL1 "C17, C4orf4" ENSG00000170891 "Cytokine like 1" Q9NRR1 4 5014586-5019458 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.0" "Cell type enhanced" "Detected in some" "Adipocytes: 14.1;Endothelial cells: 32.0;Erythroid cells: 86.6;Fibroblasts: 16.8;Hofbauer cells: 15.5;Microglial cells: 23.4" "Group enriched" "Detected in many" 5 "glioma: 21.0;melanoma: 20.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "NK-cell: 27.0" "Lineage enriched" "Detected in many" 11 "NK-cells: 27.0" "Cell line enhanced" "Detected in some" "HEL: 194.1;HUVEC TERT2: 152.3;NB-4: 382.2;WM-115: 89.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067201 Supported "Nuclear membrane,Endoplasmic reticulum" "Secreted in other tissues" NA NA 270000 "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear membrane, Endoplasmic reticulum" "HPA067201: AB_2732760" "unprognostic (2.35e-2)" "unprognostic (9.01e-3)" "unprognostic (3.56e-1)" "unprognostic (3.76e-2)" "unprognostic (1.14e-1)" "unprognostic (2.71e-1)" "unprognostic (2.09e-2)" "unprognostic (1.44e-1)" "unprognostic (7.10e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (7.43e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.18e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.25e-4)" 5.8 1.9 2.1 1.8 2.5 13.9 6.9 2.8 3.9 12.9 3.1 5.5 0.6 9.5 1.3 4.8 7.9 4.6 1.5 2.6 2.7 1.0 0.3 4.9 4.5 4.2 3.0 1.7 1.2 1.2 1.6 46.0 3.9 10.8 1.4 0.2 4.3 14.4 0.5 3.2 2.4 4.0 3.3 1.2 4.7 0.3 3.4 4.5 5.8 0.2 4.9 12.0 7.3 4.8 0.1 0.0 0.1 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.1 0.1 0.0 0.9 0.0 0.0 5.0 0.0 2.7 0.0 0.0 152.3 0.0 0.0 7.5 0.0 0.0 0.0 382.2 0.7 0.0 0.0 5.7 7.7 0.2 0.0 0.0 0.1 8.8 0.3 0.0 24.5 0.2 0.0 0.0 52.7 0.0 34.6 0.1 0.0 1.0 0.2 0.4 0.0 4.8 89.6 2.5 1.2 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.7 0.1 27.0 0.0 0.4 0.0 0.9 2.1 2.5 2.8 3.9 2.6 2.7 4.2 3.0 3.9 3.3 3.4 4.8 14.1 0.0 0.5 0.0 1.2 2.8 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.2 0.4 0.3 0.3 32.0 0.0 86.6 0.0 0.0 0.4 16.8 0.0 0.3 8.9 0.2 0.7 0.0 15.5 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 4.7 8.8 23.4 0.6 0.0 3.1 0.5 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 2.3 0.8 0.1 0.0 0.3 1.6 0.5 0.5 8.6 0.0 0.6 DAND5 "CER2, CKTSF1B3, Coco, DANTE, DTE, FLJ38607, GREM3" ENSG00000179284 "DAN domain BMP antagonist family member 5" Q8N907 19 12965159-12974760 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "heart muscle: 8.5" "Cell type enriched" "Detected in some" 7 "Cardiomyocytes: 17.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 16 "SH-SY5Y: 19.8" "Not detected" "Not detected" "HPA043493, HPA049472" Uncertain Approved Mitochondria "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043493: AB_2732505, HPA049472: AB_2680781" "unprognostic (1.18e-2)" "unprognostic (4.63e-2)" "unprognostic (7.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.82e-2)" "unprognostic (8.71e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-1)" "unprognostic (5.95e-3)" "unprognostic (7.27e-3)" "unprognostic (8.17e-2)" "unprognostic (2.15e-1)" "unprognostic (2.48e-10)" "unprognostic (4.43e-1)" "unprognostic (2.48e-2)" "unprognostic (6.77e-2)" "unprognostic (1.37e-1)" 0.1 0.9 0.4 0.1 0.4 0.7 0.3 0.9 0.4 0.1 1.6 2.0 0.2 0.1 0.2 0.1 0.1 0.3 8.5 0.4 0.3 0.1 0.0 0.1 0.1 0.5 0.2 0.1 0.2 0.8 0.1 0.0 0.7 0.1 0.3 0.7 0.4 0.0 0.1 0.3 0.3 0.3 0.2 0.0 0.3 0.3 0.5 0.1 0.2 0.2 0.0 0.1 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.8 0.3 0.0 0.0 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.7 0.4 1.2 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.1 0.0 1.0 19.8 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.1 1.2 0.1 0.4 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.4 1.5 0.4 0.1 0.4 0.0 0.1 0.4 0.4 0.9 0.4 0.4 0.3 0.5 0.2 0.7 0.2 0.5 0.8 0.5 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.7 1.3 17.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.5 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.3 0.3 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.6 0.0 2.1 0.5 0.1 0.2 0.3 0.3 0.0 0.1 0.1 0.5 0.1 DCD "AIDD, DCD-1, DSEP, HCAP, PIF" ENSG00000161634 Dermcidin P81605 12 54644589-54648493 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 2476.8" "Cell type enriched" "Detected in some" 355 "Melanocytes: 8167.8" "Cancer enriched" "Detected in some" 9 "breast cancer: 91.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA063967 Enhanced "Secreted in other tissues" NA NA 410000000 "Cluster 42: Non-specific - Transcription" "Cluster 61: Skin - Cornification" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA063967: AB_2685163" "unprognostic (3.55e-2)" "unprognostic (1.61e-1)" 100.2 0.4 3.5 0.3 3.3 1.1 354.3 3.4 5.4 0.3 3.8 0.7 0.2 0.7 0.9 0.5 0.2 0.8 1.3 3.5 3.3 0.2 0.9 0.6 0.2 3.3 3.6 0.4 1.0 0.0 0.5 0.1 3.5 0.4 0.2 0.5 0.5 0.1 14.0 2476.8 0.7 0.1 3.0 0.4 0.7 1.1 3.2 0.3 0.5 0.0 0.2 0.2 0.7 4.1 0.2 0.3 0.4 0.4 0.3 0.4 0.4 0.5 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.4 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.2 0.1 0.3 0.2 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 1.9 0.4 0.5 0.4 0.3 0.6 0.5 0.4 0.3 0.2 0.4 0.5 0.5 1.1 0.9 0.7 0.5 0.6 0.2 3.5 3.3 3.4 5.4 3.5 3.3 3.3 3.6 3.5 3.0 3.2 4.1 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.1 0.0 0.0 8167.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.4 0.2 0.0 23.0 0.0 1.0 0.0 0.0 0.0 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DEFA1 "DEF1, DEFA2, HNP-1, MRS" ENSG00000206047 "Defensin alpha 1" P59665 8 6977649-6980080 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 18020.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "NB-4: 2.1" "CAB032548, HPA052517" Enhanced "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "CAB032548: AB_2277258, HPA052517: AB_2681860" 31.6 4.3 0.7 0.6 0.8 18020.9 16.8 0.5 3.0 4.0 0.6 4.1 0.0 11.3 0.0 3.2 2.2 1.3 62.5 0.5 0.6 15.0 91.6 560.5 3.5 0.7 0.7 4.1 5.5 0.1 20.6 11.4 0.7 2.7 0.0 0.3 14.5 0.0 16.8 40.3 2.3 0.0 0.8 1803.8 6.4 3.1 0.8 37.0 15.8 0.0 0.8 3.4 5.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.5 3.0 0.5 0.6 0.7 0.7 0.7 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 DEFA1B ENSG00000240247 "Defensin alpha 1B" P59665 8 6996766-6999195 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 872.0" "Cell type enriched" "Detected in single" 37 "T-cells: 3.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052517 Supported "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA052517: AB_2681860" 2.3 0.3 0.1 0.8 0.1 872.0 1.1 0.1 2.0 0.0 0.1 0.2 0.0 0.9 0.0 0.1 0.1 0.0 3.8 0.2 0.1 0.9 9.1 52.1 0.0 0.2 0.1 0.3 0.1 0.0 1.4 7.2 0.4 0.1 0.0 0.1 9.4 0.0 0.8 0.2 0.2 0.0 0.1 150.4 0.6 0.1 0.4 27.8 1.2 5.8 1.4 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.0 0.2 0.1 0.2 0.1 0.4 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 DEFA3 "DEF3, HNP-3" ENSG00000239839 "Defensin alpha 3" P59666 8 7015869-7018297 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "bone marrow: 37615.2" "Cell type enhanced" "Detected in some" "B-cells: 17.9;Erythroid cells: 10.1;Hepatocytes: 17.0;Macrophages: 5.7;Plasma cells: 4.0;T-cells: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 19 "neutrophil: 854.3" "Lineage enriched" "Detected in many" 19 "granulocytes: 854.3" "Cell line enriched" "Detected in single" 8 "NB-4: 1.5" HPA052517 Supported "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA052517: AB_2681860" "unprognostic (8.21e-2)" 8.8 1.2 0.5 1.0 0.3 37615.2 5.0 0.2 1.2 2.0 0.3 1.3 0.0 5.6 0.0 1.0 0.7 0.2 16.1 0.2 0.3 4.4 26.1 180.2 5.3 0.4 0.6 1.3 1.6 0.0 7.6 18.8 0.5 0.8 0.0 0.2 24.2 0.0 5.0 42.1 0.7 0.0 0.5 589.4 1.8 0.6 0.6 147.9 4.5 1.1 1.3 1.1 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 24.4 3.6 44.3 1.2 1.6 2.3 1.0 0.8 1.0 1.1 6.9 0.3 854.3 0.4 2.6 1.4 0.3 6033.6 0.5 0.3 0.2 1.2 0.2 0.3 0.4 0.6 0.5 0.5 0.6 0.2 0.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.8 17.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 DEFA4 "DEF4, HP-4" ENSG00000164821 "Defensin alpha 4" P12838 8 6935820-6938306 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "bone marrow: 2702.9" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Hepatocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "neutrophil: 13.1" "Lineage enriched" "Detected in many" 13 "granulocytes: 13.1" "Cell line enriched" "Detected in single" 8 "THP-1: 6.8" HPA051266 Enhanced "Secreted to blood" NA NA 98000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA051266: AB_2681414" 0.7 0.1 0.0 0.2 0.0 2702.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 2.7 14.2 0.6 0.0 0.0 0.0 0.1 0.0 0.7 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.4 2.0 0.1 0.0 0.0 46.4 0.1 0.1 0.0 8.9 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 768 "intestine: 9759.8" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 1740.2;Undifferentiated cells: 1753.0" "Cancer enhanced" "Detected in many" "cervical cancer: 181.1;colorectal cancer: 147.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BEWO: 28.3;NB-4: 24.2;RPMI-8226: 26.6;SH-SY5Y: 19.6;U-2197: 8.5" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Yes NA 110000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles Midbody "CAB069919: AB_905358, HPA015309: , HPA015775: AB_1847594" "prognostic favorable (9.44e-5)" "unprognostic (3.91e-2)" 0.3 0.4 0.1 12.7 0.1 0.2 0.5 0.1 0.5 0.0 0.1 56.6 5185.1 3.9 0.1 0.8 0.0 0.0 0.4 0.1 0.2 0.2 1.1 0.4 6.0 0.1 0.2 0.4 0.8 0.0 1.1 0.0 0.2 0.7 0.2 0.1 0.7 0.0 0.3 0.3 9759.8 0.1 0.1 0.4 0.9 0.8 0.2 0.4 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 2.5 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.5 0.1 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 325.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 399.9 0.0 0.0 0.0 1740.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.0 1753.0 0.0 DEFA6 "DEF6, HD-6" ENSG00000164822 "Defensin alpha 6" Q01524 8 6924697-6926076 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 863 "intestine: 4819.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 448.9;Undifferentiated cells: 904.1" "Group enriched" "Detected in many" 5 "cervical cancer: 21.2;colorectal cancer: 75.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 14.7;NB-4: 15.9;RPMI-8226: 19.7;SH-SY5Y: 12.2;U-2197: 5.7" HPA019462 Enhanced "Secreted to digestive system" NA NA 260000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019462: AB_1847595" "unprognostic (7.48e-3)" "unprognostic (1.63e-1)" "unprognostic (1.34e-1)" 0.1 0.2 0.0 5.5 0.0 0.3 0.2 0.0 0.0 0.0 0.0 25.7 2862.9 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.2 3.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.1 0.3 3.3 0.0 0.3 0.0 0.2 0.6 4819.9 0.0 0.0 0.2 0.4 0.6 0.0 2.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 1.1 12.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.4 0.0 0.0 0.0 448.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 904.1 0.0 DEFB1 "BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822" ENSG00000164825 "Defensin beta 1" P60022 8 6870592-6877936 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 1746.1;pancreas: 747.8;salivary gland: 1975.0" "Cell type enriched" "Detected in many" 6 "Distal tubular cells: 13300.4" "Cancer enhanced" "Detected in many" "renal cancer: 522.9" "Group enriched" "Detected in many" 4 "amygdala: 1.2;cerebellum: 1.5;hypothalamus: 1.0;midbrain: 2.4;thalamus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 43.3" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.31e-2)" "unprognostic (8.35e-3)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-3)" "unprognostic (4.41e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.77e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (5.94e-4)" "unprognostic (3.24e-1)" "prognostic favorable (1.90e-5)" "unprognostic (9.62e-2)" "unprognostic (2.86e-2)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" 11.1 0.7 1.2 1.5 0.0 5.3 41.5 1.5 0.4 305.4 0.3 20.7 5.1 6.2 16.4 190.6 21.2 54.9 1.3 0.0 1.0 1746.1 248.4 5.7 0.0 0.0 2.4 0.5 747.8 6.9 12.7 2.1 0.2 37.9 11.5 1.9 1975.0 24.5 2.9 217.6 8.7 0.3 0.0 0.3 33.3 0.4 3.0 3.0 3.6 0.0 9.0 11.6 152.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.0 0.5 0.0 2.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 4.2 0.0 0.1 0.3 0.0 2.7 1.2 43.3 0.3 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.5 0.4 0.0 1.0 0.0 2.4 0.2 0.0 3.0 0.2 0.7 3.2 4.5 0.0 6.8 90.1 641.5 210.5 134.9 0.4 46.9 26.9 0.1 1976.0 57.2 982.1 0.0 11.8 0.4 117.6 13300.4 1860.0 0.0 339.5 223.6 8.8 15.7 0.0 0.0 295.4 0.9 19.0 1.5 1529.3 0.0 0.0 3.3 319.3 3.6 0.0 0.0 8.6 46.8 4.4 7.3 0.1 17.4 17.0 7.2 0.0 15.3 0.6 0.0 0.0 0.0 156.9 91.2 0.0 1.2 537.6 59.1 218.9 9.5 0.7 0.0 1.4 14.3 0.0 0.0 237.0 537.6 3.7 13.8 0.0 15.4 257.0 DEFB103A "DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3" ENSG00000176797 "Defensin beta 103A" P81534 8 7881392-7882663 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.6;salivary gland: 3.2;vagina: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 5.8;LHCN-M2: 1.7;U-2197: 3.0" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.6 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB103B ENSG00000177243 "Defensin beta 103B" P81534 8 7428888-7430348 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB104A "DEFB-4, DEFB104, DEFB4" ENSG00000176782 "Defensin beta 104A" Q8WTQ1 8 7836436-7841242 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 763 "epididymis: 1308.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045292: AB_2679288" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1308.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB104B ENSG00000177023 "Defensin beta 104B" Q8WTQ1 8 7470308-7475082 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" NA NA "HPA045292: AB_2679288" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB105A "DEFB-5, DEFB105" ENSG00000186562 "Defensin beta 105A" Q8NG35 8 7821966-7823889 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB105B ENSG00000186599 "Defensin beta 105B" Q8NG35 8 7487679-7489593 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12966 "epididymis: 2383.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "NB-4: 4.2" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2383.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB106A "DEFB-6, DEFB106" ENSG00000186579 "Defensin beta 106A" Q8N104 8 7825139-7829053 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16935 "epididymis: 3003.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "NB-4: 2.2" HPA045592 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "HPA045592: AB_2679378" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3003.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB106B ENSG00000187082 "Defensin beta 106B" Q8N104 8 7482504-7486400 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 685 "epididymis: 68.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045592 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045592: AB_2679378" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB107A "DEFB-7, DEFB107" ENSG00000186572 "Defensin beta 107A" Q8IZN7 8 7811720-7815716 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 1392 "epididymis: 139.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045626: AB_2679396" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB107B HsT21816 ENSG00000198129 "Defensin beta 107B" Q8IZN7 8 7495911-7509311 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5377 "epididymis: 537.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045626: AB_2679396" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 537.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB108B ENSG00000184276 "Defensin beta 108B" Q8NET1 11 71833200-71837710 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "epididymis: 12.8" "Cell type enriched" "Detected in single" 18 "Collecting duct cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 67: Proximal tubular cells - Tubular reabsorption" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB110 "DEFB-10, DEFB-11, DEFB111" ENSG00000203970 "Defensin beta 110" Q30KQ9 6 50009138-50021994 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4674 "epididymis: 871.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "NB-4: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 871.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB113 DEFB-13 ENSG00000214642 "Defensin beta 113" Q30KQ7 6 49968677-49969625 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 465 "epididymis: 46.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB114 DEFB-14 ENSG00000177684 "Defensin beta 114" Q30KQ6 6 49960249-49964164 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 496 "epididymis: 49.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB115 DEFB-15 ENSG00000215547 "Defensin beta 115" Q30KQ5 20 31257664-31259632 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "epididymis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "U-2 OS: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA053160 Uncertain "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "HPA053160: AB_2682062" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB116 DEFB-16 ENSG00000215545 "Defensin beta 116" Q30KQ4 20 31303212-31308585 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047430 Uncertain "Secreted in male reproductive system" NA NA "HPA047430: AB_10964749" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB118 "C20orf63, DEFB-18, dJ1018D12.3, ESC42" ENSG00000131068 "Defensin beta 118" Q96PH6 20 31368601-31373923 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9912 "epididymis: 991.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" HPA042634 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA042634: AB_10797505" "unprognostic (3.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 991.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB119 "DEFB-19, DEFB-20, DEFB120" ENSG00000180483 "Defensin beta 119" Q8N690 20 31377164-31390590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 1925.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.6;Cone photoreceptor cells: 39.6;Early spermatids: 61.9;Late spermatids: 99.8;Rod photoreceptor cells: 150.2" "Cancer enriched" "Detected in single" 67 "testis cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.5" HPA043059 Supported "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA043059: AB_10797025" "unprognostic (2.03e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 1925.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 155.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 331.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 61.9 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 99.8 12.5 0.8 0.0 0.0 0.0 22.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 150.2 13.1 0.0 0.0 17.4 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB121 DEFB-21 ENSG00000204548 "Defensin beta 121" Q5J5C9 20 31404845-31412838 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11866 "epididymis: 2605.3" "Group enriched" "Detected in some" 22 "Early spermatids: 14.5;Late spermatids: 5.4;Spermatocytes: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "NB-4: 3.1" "Not detected" "Not detected" HPA079460 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA079460: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2605.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB123 DEFB-23 ENSG00000180424 "Defensin beta 123" Q8N688 20 31440632-31450257 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 370 "epididymis: 158.8;testis: 148.1" "Group enriched" "Detected in some" 4 "Early spermatids: 14.0;Late spermatids: 50.4" "Cancer enriched" "Detected in single" 17 "testis cancer: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (9.16e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 148.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 50.4 5.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 5.2 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB124 DEFB-24 ENSG00000180383 "Defensin beta 124" Q8NES8 20 31465506-31476757 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 5.9;testis: 7.1" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Endometrial stromal cells: 6.4;Respiratory ciliated cells: 4.0;Smooth muscle cells: 2.1" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.9" "Region enriched" "Detected in single" 6 "cerebral cortex: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 2.7;HMC-1: 1.5;U-2 OS: 1.1;WM-115: 5.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (1.24e-2)" "unprognostic (9.76e-3)" "unprognostic (1.27e-1)" "unprognostic (3.23e-3)" "unprognostic (6.92e-3)" "unprognostic (3.69e-2)" "unprognostic (3.37e-2)" "unprognostic (1.78e-1)" "unprognostic (9.07e-2)" "unprognostic (4.43e-1)" "unprognostic (3.32e-7)" "unprognostic (1.56e-2)" "unprognostic (1.29e-1)" "unprognostic (4.42e-2)" "unprognostic (4.28e-1)" 3.1 0.4 0.2 0.2 0.1 0.0 1.7 0.1 1.5 3.7 1.7 2.1 0.0 3.2 2.7 0.6 5.9 0.0 0.9 0.2 0.2 0.4 0.1 0.7 0.5 0.2 0.2 0.6 0.2 0.8 0.9 0.1 0.2 1.2 0.6 0.0 0.6 3.0 1.0 0.4 0.9 0.5 0.1 0.8 0.7 7.1 0.1 0.2 1.0 0.8 0.5 1.4 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 1.5 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 6.4 0.2 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 2.1 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DEFB125 DEFB-25 ENSG00000178591 "Defensin beta 125" Q8N687 20 87250-97094 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "epididymis: 1.5;seminal vesicle: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB126 "bA530N10.1, C20orf8, DEFB-26" ENSG00000125788 "Defensin beta 126" Q9BYW3 20 142590-145751 "Disease related genes, Predicted secreted proteins" Fertilization "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 297 "epididymis: 1285.4" "Cell type enhanced" "Detected in single" "Prostatic glandular cells: 1.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.0;OE19: 3.4" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.16e-1)" "unprognostic (1.21e-1)" "unprognostic (3.16e-2)" "unprognostic (2.41e-2)" "unprognostic (2.32e-1)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1285.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 3.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.6 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.1 0.1 DEFB127 "bA530N10.2, C20orf73, DEF-27" ENSG00000088782 "Defensin beta 127" Q9H1M4 20 157454-159163 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1158 "epididymis: 1077.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1077.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB128 DEFB-28 ENSG00000185982 "Defensin beta 128" Q7Z7B8 20 187853-189711 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11940 "epididymis: 1193.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1193.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB129 "bA530N10.3, C20orf87, DEFB-29" ENSG00000125903 "Defensin beta 129" Q9H1M3 20 227258-229886 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 585 "epididymis: 1943.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 2.6;SH-SY5Y: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014581 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "HPA014581: AB_2732410" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1943.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB130A "DEFB-30, DEFB130, DEFB30" ENSG00000232948 "Defensin beta 130A" P0DP74 8 12310962-12318316 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "epididymis: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB130B ENSG00000233050 "Defensin beta 130B" P0DP73 8 12064389-12071747 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "epididymis: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB131A "DEFB-31, DEFB131" ENSG00000186146 "Defensin beta 131A" P59861 4 9444534-9450514 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "epididymis: 167.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "thyroid cancer: 1.3" "Group enriched" "Detected in some" 4 "medulla oblongata: 1.2;pons: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "TIME: 2.1" "Secreted in other tissues" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "unprognostic (2.11e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 14.9 0.0 167.4 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 14.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 1.2 0.2 1.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB131B ENSG00000225805 "Defensin beta 131B" A0A096LNP1 11 71878453-71884561 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "epididymis: 68.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 15.6" "Secreted in male reproductive system" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "unprognostic (5.87e-2)" "unprognostic (1.44e-1)" "unprognostic (4.78e-2)" "unprognostic (7.44e-2)" "unprognostic (3.57e-2)" "unprognostic (3.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (7.45e-2)" "unprognostic (1.41e-1)" "unprognostic (1.43e-1)" "unprognostic (5.21e-2)" "unprognostic (3.39e-1)" "unprognostic (1.05e-2)" "unprognostic (3.62e-1)" 0.2 0.6 0.7 1.1 0.5 0.4 0.0 0.7 1.3 0.0 0.0 0.7 1.8 0.4 68.9 0.1 0.0 2.5 0.4 0.4 0.2 0.5 0.0 0.2 1.8 0.5 0.5 1.2 0.0 0.0 0.0 0.2 1.7 0.4 0.0 3.6 0.7 0.1 0.4 0.8 1.0 0.0 0.2 0.7 0.6 0.8 0.7 0.0 3.2 0.0 0.0 1.0 0.0 1.3 0.5 0.0 3.1 1.4 0.0 0.0 0.4 3.6 0.0 0.0 0.0 4.4 2.8 3.0 1.1 0.0 1.5 3.4 0.0 0.0 0.0 2.8 2.8 3.8 0.0 2.5 0.0 4.8 1.6 0.0 0.0 0.0 0.0 1.1 0.0 6.2 7.3 5.9 0.0 3.2 2.1 0.9 0.5 3.7 3.7 3.0 15.6 1.0 0.0 1.1 2.9 1.6 2.5 1.4 2.6 2.5 3.0 0.4 2.1 1.2 3.4 2.0 0.3 2.5 1.1 4.4 2.0 2.8 0.8 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.7 0.2 0.0 0.7 0.5 0.7 1.3 0.4 0.2 0.5 0.5 1.7 0.2 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB132 "DEFB32, RP5-1103G7.6" ENSG00000186458 "Defensin beta 132" Q7Z7B7 20 257724-261096 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 271.2" "Cell type enriched" "Detected in some" 7 "Collecting duct cells: 11.0" "Group enriched" "Detected in some" 4 "liver cancer: 0.8;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046399 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA046399: AB_10960992" "unprognostic (9.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.54e-2)" 25.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 271.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 1.5 0.0 11.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 DEFB133 ENSG00000214643 "Defensin beta 133" Q30KQ1 6 49946021-49950265 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 130 "epididymis: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB134 ENSG00000205882 "Defensin beta 134" Q4QY38 8 11993174-11996312 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "epididymis: 13.0" "Group enriched" "Detected in some" 21 "Early spermatids: 48.3;Late spermatids: 33.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (3.80e-2)" "unprognostic (2.20e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 0.0 13.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB135 ENSG00000205883 "Defensin beta 135" Q30KP9 8 11982321-11984590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 50 "epididymis: 34.8" "Group enriched" "Detected in some" 9 "Early spermatids: 2.8;Late spermatids: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 2.2" "Region enhanced" "Detected in single" "white matter: 1.5" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.6 0.0 0.5 0.0 0.0 0.0 34.8 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.6 0.3 0.3 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB136 DEFB137 ENSG00000205884 "Defensin beta 136" Q30KP8 8 11973937-11974599 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "epididymis: 1.2" "Cell type enhanced" "Detected in single" "Late spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA068255 Enhanced "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 34: Spermatids - Unknown function" "HPA068255: AB_2732780" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB4A "DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1" ENSG00000171711 "Defensin beta 4A" O15263 8 7894677-7896716 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 124.1" "Group enriched" "Detected in some" 8 "Basal respiratory cells: 79.5;Club cells: 38.3;Exocrine glandular cells: 37.4;Pancreatic endocrine cells: 41.0" "Group enriched" "Detected in many" 6 "head and neck cancer: 32.2;melanoma: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "EFO-21: 1.4" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (6.96e-2)" "unprognostic (1.17e-2)" "unprognostic (2.72e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 124.1 0.1 3.6 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.0 0.0 3.2 0.4 0.0 0.0 0.0 7.3 0.0 0.0 5.0 0.0 0.0 7.6 0.2 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.5 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.1 0.0 5.6 0.0 4.3 0.0 5.3 0.2 0.0 0.0 0.0 0.0 37.4 0.0 0.0 3.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.0 1.1 0.0 0.0 0.1 0.0 0.1 3.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 DEFB4B DEFB4P ENSG00000177257 "Defensin beta 4B" O15263 8 7414855-7416863 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.0;lymphoid tissue: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DHH "HHG-3, MGC35145" ENSG00000139549 "Desert hedgehog signaling molecule" O43323 12 49086656-49094801 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 16.7" "Cell type enriched" "Detected in some" 7 "Granulosa cells: 17.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AN3-CA: 1.8;EFO-21: 2.3;HUVEC TERT2: 1.5;K-562: 5.6;TIME: 2.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "spinal cord: 8.2" "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.56e-2)" "unprognostic (2.05e-3)" "unprognostic (1.14e-1)" "unprognostic (2.93e-3)" "unprognostic (2.36e-4)" "unprognostic (1.29e-1)" "unprognostic (7.22e-3)" "unprognostic (8.21e-2)" "unprognostic (5.92e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (8.00e-2)" "unprognostic (1.00e-1)" "unprognostic (6.97e-2)" 0.8 0.2 0.2 0.5 0.3 0.0 0.7 0.7 0.5 0.5 0.1 0.4 0.0 0.6 0.2 0.3 0.4 0.3 0.6 0.2 0.1 0.7 0.1 0.5 0.1 0.5 0.4 0.3 0.1 0.0 0.6 0.6 0.4 0.4 0.1 0.0 0.3 0.3 0.1 0.3 0.4 0.4 0.6 0.2 0.3 16.7 0.4 0.0 0.3 0.4 0.0 0.7 0.5 0.8 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.5 0.2 0.1 0.5 0.4 0.4 0.6 0.4 0.8 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 17.1 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.7 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "intestine: 216.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 317.3;Paneth cells: 154.2;Proximal enterocytes: 527.9;Undifferentiated cells: 148.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" NA NA 42000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 56: Intestine - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Golgi apparatus" "HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209" "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" 10.0 10.5 6.9 5.4 7.9 4.4 10.9 6.7 9.8 9.5 9.0 74.3 216.0 5.7 1.9 14.6 7.3 2.4 17.2 8.6 9.0 21.9 14.8 4.3 2.4 7.4 7.5 5.1 15.4 9.5 13.3 2.0 7.9 8.0 57.1 22.4 10.3 4.5 16.7 14.4 177.0 6.3 6.6 4.7 11.7 17.0 8.2 2.1 11.9 9.9 3.6 6.8 10.5 7.7 13.9 10.0 3.6 13.8 1.2 2.5 10.6 3.8 2.6 11.9 10.7 22.2 10.1 0.8 1.9 4.0 4.8 13.9 11.5 6.7 10.5 7.1 15.2 3.7 10.1 35.6 5.5 3.0 1.2 2.2 7.3 8.6 6.5 1.9 8.8 11.2 36.1 9.3 5.9 12.5 12.6 5.5 4.5 14.2 0.4 15.2 12.8 22.0 9.9 11.4 10.4 4.9 16.0 12.9 33.3 6.6 19.1 3.6 4.8 1.6 18.2 7.6 10.0 14.1 16.7 4.4 6.5 9.3 5.5 0.1 0.1 0.4 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.0 6.9 7.9 6.7 9.8 8.6 9.0 7.4 7.5 7.9 6.6 8.2 7.7 9.1 0.0 1.5 4.2 3.3 4.2 8.9 2.8 4.0 20.7 14.6 13.3 9.6 2.8 2.4 7.3 129.3 7.9 1.4 317.3 58.7 10.7 22.9 10.2 5.0 6.7 12.1 31.5 8.2 11.4 4.7 3.4 8.6 6.8 0.0 5.3 5.3 12.7 3.5 16.8 9.6 72.2 2.0 1.9 4.2 30.5 4.1 2.6 19.6 2.8 3.6 15.8 1.0 4.0 2.0 7.5 154.2 5.3 9.1 11.7 527.9 43.1 3.8 71.0 0.0 5.9 5.9 27.7 6.5 12.0 6.0 7.0 3.1 9.3 148.5 15.2 DHRS13 "MGC23280, SDR7C5" ENSG00000167536 "Dehydrogenase/reductase 13" Q6UX07 17 28897781-28903079 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 55.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA022991 Uncertain Approved Vesicles "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA022991: AB_1853865" "unprognostic (8.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.35e-1)" "unprognostic (1.21e-2)" "unprognostic (6.37e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (2.38e-1)" "unprognostic (4.74e-2)" "unprognostic (5.65e-2)" "unprognostic (1.20e-2)" "unprognostic (7.57e-2)" "unprognostic (1.73e-2)" "unprognostic (3.72e-2)" "unprognostic (2.63e-1)" "unprognostic (7.22e-3)" "unprognostic (2.55e-1)" 3.1 7.0 9.9 5.7 8.6 41.8 5.4 17.1 9.6 6.4 11.8 4.8 4.4 3.0 6.6 8.8 4.1 2.9 2.8 8.6 15.3 12.2 23.6 4.7 6.6 13.0 14.9 3.5 6.6 7.9 6.3 4.5 14.0 19.4 3.6 8.3 12.7 10.6 1.3 7.4 4.0 2.2 10.1 10.2 5.9 3.0 13.0 4.6 4.7 2.3 6.9 9.5 6.3 9.5 12.1 7.6 17.4 22.2 2.6 3.8 16.8 6.4 8.3 11.6 17.7 23.5 7.1 32.8 10.7 1.4 13.4 10.5 24.8 7.1 4.9 33.5 23.9 18.4 13.9 13.0 6.5 9.5 2.1 2.8 6.3 7.3 7.7 8.1 3.6 22.7 42.3 11.0 2.3 21.7 20.9 15.9 10.7 31.4 1.0 32.8 16.4 25.5 21.8 20.2 24.8 20.8 10.1 69.5 13.9 9.1 46.4 15.2 1.2 3.7 11.1 9.0 8.9 25.5 25.7 20.7 11.0 11.9 9.4 0.9 4.4 3.1 8.5 6.9 10.4 7.1 10.8 10.7 5.9 8.6 10.9 8.1 55.3 9.4 6.8 3.2 11.4 5.8 9.9 8.6 17.1 9.6 8.6 15.3 13.0 14.9 14.0 10.1 13.0 9.5 2.4 3.2 4.2 2.3 6.7 1.5 10.2 12.3 12.0 6.1 7.1 5.7 0.4 8.6 5.4 7.3 2.1 27.7 4.4 4.3 9.8 10.6 11.9 3.4 1.1 4.5 3.0 106.1 0.7 2.7 22.2 2.1 7.7 6.3 1.3 1.2 6.4 5.5 6.2 5.0 4.4 4.2 2.0 0.8 3.0 5.2 1.2 2.1 5.4 1.0 15.5 8.2 10.3 3.0 1.0 2.5 2.4 0.4 12.8 11.5 2.8 3.2 2.2 5.0 6.6 0.9 1.1 6.1 22.5 9.4 1.7 13.5 7.0 0.5 6.4 5.8 DHRS4L2 SDR25C3 ENSG00000187630 "Dehydrogenase/reductase 4 like 2" Q6PKH6 14 23969874-24006408 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 204.2;Proximal enterocytes: 326.4;Proximal tubular cells: 581.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.41e-2)" "unprognostic (2.83e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (6.02e-2)" "unprognostic (3.97e-3)" "unprognostic (7.34e-2)" "prognostic favorable (3.21e-4)" "unprognostic (1.57e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-3)" "unprognostic (6.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (3.65e-2)" 27.2 39.5 28.8 14.6 29.6 11.5 30.5 28.3 38.4 26.9 30.8 34.7 34.4 19.7 12.8 38.4 18.6 10.6 45.9 28.5 27.8 122.5 136.2 22.5 14.6 29.3 28.7 25.2 34.0 24.5 16.7 10.0 28.7 32.5 26.6 6.7 24.7 20.7 50.7 37.1 42.0 18.4 28.6 29.3 27.9 41.4 29.4 16.9 21.5 28.5 16.5 26.0 26.1 29.9 18.7 29.0 4.9 24.4 46.2 47.9 0.6 17.3 34.3 24.8 18.4 8.4 22.5 12.6 11.5 35.3 16.0 20.6 22.3 29.1 20.6 43.3 13.3 3.1 24.8 52.4 34.0 15.3 47.9 50.0 36.4 16.3 23.7 17.0 29.5 40.0 10.1 44.9 26.7 61.5 40.4 16.5 9.7 45.9 31.8 64.9 19.9 38.2 35.6 23.7 26.0 15.7 24.5 21.5 15.0 10.3 25.2 24.5 20.8 12.9 13.4 15.4 8.8 25.5 21.1 3.8 11.1 23.7 18.8 4.8 56.3 6.9 19.4 47.2 20.1 21.9 20.9 22.2 45.4 17.4 21.0 19.1 2.6 17.2 29.3 37.4 21.8 33.6 28.8 29.6 28.3 38.4 28.5 27.8 29.3 28.7 28.7 28.6 29.4 29.9 39.3 16.0 29.6 10.4 17.8 27.8 46.1 56.8 27.9 9.9 45.5 54.4 17.2 47.1 34.3 25.8 2.1 21.2 22.9 37.9 127.2 40.0 20.7 20.6 20.1 32.0 37.3 24.2 7.3 55.7 7.3 36.4 13.3 16.5 17.7 31.8 50.0 204.2 146.1 11.8 6.7 61.7 42.7 55.9 42.8 35.4 43.8 41.9 51.6 10.3 65.0 79.5 35.0 10.1 8.5 30.4 54.9 37.2 10.8 32.5 326.4 581.7 28.6 8.3 32.9 24.2 32.7 17.2 1.7 42.1 40.2 13.0 21.3 37.5 78.1 42.4 DHRS7C SDR32C2 ENSG00000184544 "Dehydrogenase/reductase 7C" A6NNS2 17 9771434-9791592 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 66 "heart muscle: 125.0;skeletal muscle: 308.1;tongue: 367.4" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 87.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (6.83e-2)" 0.1 0.1 0.4 0.0 0.5 0.0 0.1 0.3 1.1 0.0 0.3 0.4 0.2 0.0 0.0 4.0 0.0 0.0 125.0 0.5 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.1 0.0 0.2 0.0 0.3 0.5 1.1 0.0 2.9 0.0 308.1 0.0 0.2 0.0 0.4 0.0 0.0 0.6 0.3 0.0 0.0 367.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 1.1 0.5 0.3 0.3 0.3 0.3 0.4 0.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DHRSX "DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6" ENSG00000169084 "Dehydrogenase/reductase X-linked" Q8N5I4 X 2219506-2502805 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA003035, HPA075955" Approved Uncertain "Mitotic spindle,Cytosol" "Secreted to blood" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "Mitotic spindle" "HPA003035: AB_1080631, HPA075955: " "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-2)" "unprognostic (4.65e-3)" "unprognostic (8.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.29e-1)" "unprognostic (4.59e-3)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.08e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.69e-2)" 13.1 16.2 7.0 4.8 8.2 5.2 12.2 6.7 7.7 13.3 11.9 12.7 6.5 13.0 8.0 6.0 11.0 8.8 19.9 6.1 6.8 14.7 30.6 10.3 5.6 11.5 10.1 12.6 21.9 11.5 10.6 8.2 8.4 13.2 8.3 2.2 14.7 7.0 12.4 9.0 10.8 6.9 8.5 10.1 16.5 6.4 10.9 6.1 13.3 7.0 3.9 11.2 9.3 8.2 8.1 35.7 23.9 11.0 28.8 18.0 18.5 17.8 29.9 13.3 17.9 26.9 16.8 12.6 22.6 21.5 31.4 3.9 16.4 14.3 9.4 24.1 26.1 12.2 17.9 21.2 33.8 6.6 9.5 22.3 17.7 11.6 11.4 22.7 10.9 13.9 14.0 6.1 21.7 9.2 28.5 9.7 6.9 10.6 9.9 10.4 12.4 3.5 14.5 19.3 24.3 22.9 17.0 20.3 14.2 14.8 8.7 10.8 15.6 14.5 3.6 8.4 10.6 7.1 0.1 33.2 9.7 8.7 6.7 14.9 38.3 34.6 15.1 30.6 16.0 25.0 13.5 12.7 35.1 20.1 12.3 10.6 56.4 17.7 19.5 28.3 18.2 21.0 7.0 8.2 6.7 7.7 6.1 6.8 11.5 10.1 8.4 8.5 10.9 8.2 8.7 19.2 9.3 64.3 19.2 10.6 22.9 58.0 20.5 9.5 19.3 16.9 23.4 25.8 24.4 25.8 10.4 42.9 17.0 32.9 13.7 52.3 0.6 16.1 15.9 14.8 19.2 13.7 41.2 81.2 43.5 26.9 21.4 14.4 17.8 27.1 15.0 50.6 38.4 3.3 42.7 21.4 32.6 20.8 30.7 3.0 24.2 26.3 12.4 61.8 35.9 9.4 14.4 46.3 31.9 71.0 28.8 25.2 29.1 65.3 49.2 43.7 14.8 6.2 19.7 12.0 18.3 12.0 21.2 11.3 6.5 107.3 14.0 14.6 24.1 29.2 DIPK2A "C3orf58, DIA1, HASF, MGC33365" ENSG00000181744 "Divergent protein kinase domain 2A" Q8NDZ4 3 143971823-144048719 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.5;Cardiomyocytes: 19.6;dendritic cells: 11.3;Fibroblasts: 22.6;Hofbauer cells: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 147.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048992 Approved "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" "HPA048992: AB_2680591" "unprognostic (5.96e-2)" "unprognostic (8.54e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-1)" "unprognostic (2.43e-1)" "unprognostic (2.85e-2)" "unprognostic (3.74e-2)" "unprognostic (2.31e-2)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (3.44e-1)" "unprognostic (3.98e-1)" "prognostic unfavorable (2.92e-7)" "unprognostic (4.82e-3)" "unprognostic (2.87e-1)" "unprognostic (1.70e-1)" "unprognostic (1.50e-2)" 9.8 7.4 10.3 10.5 14.5 32.4 15.7 24.5 17.9 13.6 3.8 8.2 6.8 14.2 6.0 14.1 12.7 14.2 7.0 9.1 10.9 6.8 18.9 12.9 11.3 12.6 11.0 20.2 4.5 15.0 3.4 38.1 11.9 11.5 8.8 5.8 9.0 12.6 4.6 24.4 5.9 15.1 9.7 10.7 8.4 8.0 10.6 16.6 12.7 7.2 11.0 11.5 9.7 23.9 24.9 9.9 24.8 147.9 22.6 20.4 13.5 17.7 17.2 16.6 17.6 6.7 9.8 15.5 13.6 6.8 11.9 13.9 37.2 14.3 25.9 7.3 13.5 23.0 9.4 10.1 9.8 21.3 10.3 17.0 7.5 10.2 15.4 16.7 26.1 7.0 4.1 43.9 21.2 6.7 7.7 10.4 15.7 10.3 6.2 11.3 12.8 17.2 10.3 29.1 16.5 0.0 12.7 5.8 5.8 6.7 15.5 11.5 12.5 14.6 7.0 22.9 20.6 17.4 6.5 22.1 23.6 10.0 19.3 24.9 11.9 20.1 3.5 7.8 5.8 8.2 4.2 3.7 14.9 7.1 3.6 3.6 3.3 9.5 10.6 9.3 3.9 6.0 10.3 14.5 24.5 17.9 9.1 10.9 12.6 11.0 11.9 9.7 10.6 23.9 23.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 1.6 11.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.1 22.6 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 3.4 2.6 0.0 0.0 0.0 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DKK1 "DKK-1, SK" ENSG00000107984 "Dickkopf WNT signaling pathway inhibitor 1" O94907 10 52314281-52318042 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.0;placenta: 48.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 486.2;Endometrial stromal cells: 337.6;Pancreatic endocrine cells: 194.6;Prostatic glandular cells: 992.9;Urothelial cells: 320.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1141.1;BJ hTERT+: 620.0;CACO-2: 1011.3;fHDF/TERT166: 1590.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.65e-2)" "unprognostic (4.21e-2)" "unprognostic (7.09e-2)" "unprognostic (7.99e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.35e-8)" "unprognostic (7.93e-2)" "prognostic unfavorable (7.80e-6)" "unprognostic (1.54e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (7.47e-3)" "unprognostic (4.05e-1)" "unprognostic (1.19e-1)" "unprognostic (2.06e-2)" 22.0 0.3 0.6 0.3 0.8 0.0 5.6 1.1 0.9 34.0 0.4 0.3 0.1 1.8 0.0 7.9 0.4 3.9 0.7 0.5 1.5 0.6 0.2 1.2 0.4 0.6 1.6 1.0 0.2 0.1 0.1 48.9 0.8 4.8 0.1 7.0 2.3 1.9 0.3 16.5 0.2 0.2 0.7 0.8 1.2 0.2 1.7 0.0 0.3 0.0 0.5 21.9 10.6 0.6 315.3 215.8 0.1 32.4 149.6 30.4 0.1 1141.1 620.0 383.8 202.5 1011.3 64.2 0.0 1.6 1590.5 93.5 245.1 0.3 130.7 361.3 0.1 0.7 0.0 4.4 26.2 31.8 0.0 0.1 30.3 16.0 83.0 488.3 19.8 35.8 0.0 0.0 0.1 255.8 135.7 0.0 0.1 0.2 13.7 543.9 0.2 34.8 0.0 148.6 25.6 0.2 342.4 102.8 1.1 17.7 0.4 1.1 0.9 78.9 0.2 0.2 338.5 211.9 0.1 0.3 0.1 4.6 0.1 37.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.1 0.9 0.5 1.5 0.6 1.6 0.8 0.7 1.7 0.6 1.9 25.6 0.0 0.0 1.0 5.4 486.2 28.5 0.0 0.2 0.8 6.9 1.1 0.0 15.2 0.0 0.0 4.6 0.0 0.9 0.0 10.7 1.2 11.0 337.6 8.5 0.0 0.0 1.2 4.1 4.0 91.5 2.6 8.1 4.5 0.0 1.1 0.0 9.3 0.0 2.2 2.4 6.1 0.0 1.6 0.6 0.0 4.9 0.0 1.0 0.0 6.1 0.0 1.5 0.2 194.6 5.0 0.0 1.3 992.9 0.4 0.0 9.8 0.4 0.0 0.0 10.6 0.4 2.2 1.4 3.1 8.3 2.8 0.0 1.0 320.0 DKK2 ENSG00000155011 "Dickkopf WNT signaling pathway inhibitor 2" Q9UBU2 4 106921802-107283806 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 15.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.6;Fibroblasts: 18.7;Hofbauer cells: 16.8;Inhibitory neurons: 32.5;Langerhans cells: 11.8;Suprabasal keratinocytes: 7.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 22.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebral cortex: 1.5;midbrain: 5.0;pons: 6.3;thalamus: 5.7" "CAB009727, HPA052611" Uncertain Supported "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "CAB009727: AB_2091492, HPA052611: AB_2732576" "unprognostic (3.14e-3)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (3.21e-2)" "unprognostic (9.75e-2)" "unprognostic (3.68e-1)" "unprognostic (1.04e-3)" "unprognostic (2.47e-2)" "unprognostic (5.11e-1)" "unprognostic (5.21e-2)" "unprognostic (3.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (6.86e-2)" "unprognostic (3.22e-1)" "unprognostic (4.58e-2)" 1.4 0.8 0.4 0.4 1.4 0.0 3.0 0.0 1.5 15.2 1.2 1.7 0.0 1.0 0.4 1.2 0.5 0.7 2.2 0.7 0.6 0.2 0.2 5.3 0.7 0.9 4.5 4.4 0.2 0.6 1.5 2.8 0.3 2.3 0.5 0.4 1.3 1.7 1.9 4.7 0.3 0.6 0.2 1.3 0.1 0.1 2.3 1.0 0.9 1.2 3.0 0.2 0.8 0.8 0.0 0.0 3.6 0.0 0.6 0.3 0.0 0.1 0.3 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 1.5 0.7 0.6 0.9 4.5 0.3 0.2 2.3 0.8 2.6 0.0 0.0 0.3 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.1 5.4 0.0 0.0 5.2 0.0 0.2 18.7 0.0 0.1 0.0 0.0 3.3 0.0 16.8 0.0 32.5 0.0 0.0 0.3 11.8 0.0 4.1 0.3 7.2 2.8 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 7.4 0.0 0.8 2.0 0.0 0.0 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DKK4 ENSG00000104371 "Dickkopf WNT signaling pathway inhibitor 4" Q9UBT3 8 42374063-42377229 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;esophagus: 4.9" "Group enriched" "Detected in some" 5 "Basal prostatic cells: 5.2;Early spermatids: 2.1;Pancreatic endocrine cells: 4.4;Prostatic glandular cells: 3.7;Spermatocytes: 2.2;Urothelial cells: 5.3" "Cancer enriched" "Detected in many" 20 "endometrial cancer: 174.4" "Group enriched" "Detected in some" 4 "cerebellum: 3.7;midbrain: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "OE19: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA052916 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA052916: AB_2681987" "unprognostic (1.64e-1)" "unprognostic (5.84e-2)" "unprognostic (1.97e-1)" "unprognostic (5.37e-3)" "unprognostic (3.23e-1)" "unprognostic (2.91e-2)" "unprognostic (2.13e-2)" "unprognostic (1.99e-1)" "unprognostic (6.80e-2)" "unprognostic (2.71e-2)" "unprognostic (1.63e-2)" "unprognostic (6.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (8.11e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 0.8 3.7 0.1 1.0 0.0 0.0 2.4 0.0 0.7 4.9 0.3 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 3.1 0.0 0.0 0.0 0.9 0.0 0.6 0.1 0.0 0.1 0.9 0.1 0.1 0.1 0.4 0.3 0.0 0.0 0.8 1.4 0.5 0.3 0.0 0.0 0.4 1.1 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.1 0.7 3.1 0.6 0.0 0.5 0.1 0.6 0.0 0.0 0.0 0.0 0.3 5.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.1 0.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 5.3 DKKL1 "CT34, SGY-1" ENSG00000104901 "Dickkopf like acrosomal protein 1" Q9UK85 19 49361783-49375116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 277 "testis: 344.8" "Group enriched" "Detected in some" 4 "Early spermatids: 2188.8;Late spermatids: 2340.4" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 17 "B-cells: 1.7" "Cell line enhanced" "Detected in some" "AF22: 5.1;AN3-CA: 9.8;HeLa: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025410, HPA047194" Enhanced Approved Vesicles "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 36: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB025410: , HPA047194: AB_2679979" "unprognostic (1.64e-1)" "unprognostic (5.30e-1)" "unprognostic (5.39e-4)" "unprognostic (1.85e-4)" "unprognostic (3.79e-2)" "unprognostic (4.30e-2)" "unprognostic (5.52e-4)" "unprognostic (1.00e-1)" "unprognostic (6.76e-2)" "unprognostic (4.08e-1)" "unprognostic (1.90e-1)" "unprognostic (5.65e-2)" "unprognostic (2.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.13e-1)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" 0.7 0.5 0.3 0.5 0.3 0.0 0.5 0.2 0.5 0.7 0.4 0.5 0.3 1.1 0.3 0.2 1.2 0.7 0.4 0.2 0.1 0.6 0.3 0.3 0.5 0.4 0.3 0.8 1.0 0.1 0.1 0.3 0.2 0.6 0.1 0.3 0.9 0.6 0.2 0.2 0.3 0.4 0.3 0.4 0.3 344.8 0.2 0.0 0.2 0.4 0.2 0.4 0.4 0.3 0.0 1.2 5.1 9.8 0.0 0.3 0.4 0.9 0.0 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.7 0.0 2.9 0.2 0.0 0.0 0.9 0.7 0.3 0.2 0.3 0.9 0.8 0.0 1.2 0.3 0.1 0.4 0.0 0.0 2.0 0.5 1.1 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.9 0.0 0.5 1.0 1.0 2.0 1.2 1.0 0.6 0.6 0.0 0.4 0.6 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.2 0.1 0.4 0.3 0.2 0.3 0.2 0.3 1.3 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.6 0.6 1.2 2.2 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.4 2188.8 0.5 1.0 1.9 0.0 0.0 0.2 0.5 0.2 0.7 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 2340.4 16.8 1.4 1.8 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 12.0 0.0 0.2 0.0 0.0 0.0 0.4 6.6 0.7 0.9 491.0 15.2 0.2 0.0 0.0 0.1 0.5 0.2 0.2 DMBT1 "Gp-340, GP340, hensin, muclin, SALSA, vomeroglandin" ENSG00000187908 "Deleted in malignant brain tumors 1" Q9UGM3 10 122560665-122643736 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Differentiation, Host-virus interaction, Protein transport, Transport" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 19 "intestine: 1651.4;salivary gland: 519.1" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 192.9;Intestinal goblet cells: 113.4;Paneth cells: 388.2;Proximal enterocytes: 167.8;Undifferentiated cells: 314.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 47.6;stomach cancer: 76.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 9.9;LHCN-M2: 16.4;RH-30: 40.3" "Not detected" "Not detected" HPA040778 Enhanced Approved "Centriolar satellite" "Secreted in other tissues" NA NA 5200000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Centriolar satellite" "HPA040778: AB_2677132" "unprognostic (3.32e-2)" "unprognostic (2.17e-2)" "unprognostic (3.47e-2)" "prognostic favorable (1.43e-4)" "unprognostic (8.77e-2)" "unprognostic (2.56e-2)" "unprognostic (3.70e-1)" "unprognostic (7.97e-2)" "unprognostic (1.31e-1)" "unprognostic (4.51e-1)" "unprognostic (2.22e-1)" "unprognostic (2.20e-1)" "unprognostic (1.08e-9)" "unprognostic (2.26e-1)" "unprognostic (2.92e-4)" "unprognostic (2.00e-3)" "unprognostic (2.22e-1)" 0.5 0.2 0.6 45.3 2.9 0.1 0.3 4.4 1.5 12.8 0.0 55.6 1651.4 1.7 0.0 1.6 3.9 45.7 0.1 0.5 2.3 0.1 0.1 58.4 1.0 6.1 5.2 0.1 1.8 0.0 0.2 0.0 7.2 1.7 17.0 0.0 519.1 0.0 0.3 0.1 518.7 15.3 2.3 0.0 3.8 1.5 4.2 0.1 0.0 0.2 0.2 15.4 0.0 7.8 0.2 0.2 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.5 0.2 1.1 0.0 0.4 0.0 0.2 0.0 0.0 3.2 0.5 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.0 1.3 0.5 9.9 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 40.3 6.0 0.0 0.0 0.1 3.0 0.3 0.0 0.1 0.0 0.0 0.0 1.7 0.1 0.8 0.5 2.3 5.7 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 4.4 1.5 0.5 2.3 6.1 5.2 7.2 2.3 4.2 7.8 0.0 6.4 192.9 0.7 1.1 0.0 7.0 0.4 0.0 0.0 1.5 0.9 0.7 0.0 3.8 0.0 0.0 0.0 0.0 52.4 0.0 2.1 2.9 1.1 0.2 7.3 0.0 0.0 0.0 15.1 0.0 0.4 0.0 3.5 10.1 0.0 0.0 0.0 0.0 0.0 0.1 113.4 0.0 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.7 388.2 0.0 0.0 1.7 167.8 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.8 0.0 0.0 0.0 1.8 0.0 314.4 20.3 DMKN ZD52F10 ENSG00000161249 Dermokine Q6E0U4 19 35497220-35513658 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "skin 1: 4799.0" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 8514.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.7" "Group enriched" "Detected in many" 5 "NK-cells: 11.7;T-cells: 6.4" "Cell line enhanced" "Detected in many" "A-431: 150.1;CACO-2: 182.0;CAPAN-2: 153.9;HBEC3-KT: 236.4;RPTEC TERT1: 232.2" "Region enhanced" "Detected in all" "basal ganglia: 51.9" "Low region specificity" "Detected in all" HPA029406 Enhanced Approved Nucleoplasm,Cytosol "Secreted in other tissues" NA NA 47000000 "Cluster 22: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" "HPA029406: AB_10603661" "unprognostic (5.70e-2)" "unprognostic (2.36e-2)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-2)" "unprognostic (3.82e-2)" "unprognostic (3.23e-1)" "unprognostic (1.03e-1)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.37e-6)" "unprognostic (3.50e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" 13.8 9.3 6.5 1.1 11.7 1.7 195.4 7.3 7.0 262.7 16.1 11.0 5.6 16.1 14.4 221.3 73.9 1.8 11.9 5.9 7.0 50.3 4.7 22.3 1.2 18.4 7.2 35.0 59.7 87.1 58.1 2.2 17.8 19.3 4.9 1.9 69.5 14.6 20.1 4799.0 8.4 4.2 6.6 2.9 19.9 4.1 6.6 12.2 60.0 0.2 50.6 14.1 378.5 6.2 150.1 24.0 0.0 0.1 5.7 8.7 40.5 0.5 19.6 1.0 1.4 182.0 153.9 0.0 57.5 1.4 7.3 81.8 44.5 236.4 1.9 0.7 43.0 0.0 0.0 41.3 6.8 0.0 0.5 77.6 62.3 4.2 133.2 13.4 0.0 0.0 0.8 0.2 0.5 130.2 0.1 0.0 129.2 107.9 9.7 0.2 0.0 6.2 232.2 97.4 0.4 0.0 35.6 0.1 14.9 36.7 58.5 0.0 0.3 22.3 67.1 0.8 0.6 0.9 0.3 1.1 18.8 0.3 1.4 0.0 0.0 0.0 6.4 0.0 5.5 1.7 0.5 3.1 0.0 0.1 0.1 2.0 0.0 11.7 0.0 0.2 0.0 1.3 6.5 11.7 7.3 7.0 5.9 7.0 18.4 7.2 17.8 6.6 6.6 6.2 13.9 105.8 115.3 1.0 5.9 1623.7 143.2 169.9 39.3 1.7 71.8 164.3 20.4 100.1 107.6 204.1 0.0 1.0 6.7 6.0 230.9 138.0 15.9 181.5 9.0 27.7 49.3 2.7 6.9 140.2 1.5 47.1 27.0 107.8 7.6 2.4 12.1 4.0 1.0 0.0 5.3 8.0 46.8 0.3 287.0 98.0 13.1 2.8 305.9 0.0 2.6 15.1 28.8 0.0 0.4 146.1 9.3 15.8 3.4 94.0 0.2 7.6 270.2 0.8 0.0 0.9 22.9 7.6 31.4 34.0 8514.1 2.3 15.0 0.2 14.2 77.4 DMP1 ENSG00000152592 "Dentin matrix acidic phosphoprotein 1" Q13316 4 87650280-87664361 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037465 Approved "Secreted to extracellular matrix" NA NA 64000 "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA037465: AB_10672492" "unprognostic (6.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-3)" "unprognostic (1.80e-1)" "unprognostic (4.96e-3)" "unprognostic (7.73e-2)" "unprognostic (3.88e-1)" "unprognostic (1.11e-1)" "unprognostic (1.35e-2)" "unprognostic (8.50e-9)" "unprognostic (5.82e-2)" "unprognostic (1.49e-2)" "unprognostic (2.77e-1)" "unprognostic (1.74e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 34.5;kidney: 34.2" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 715.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" NA NA 420000 "Cluster 49: Eosinophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" 4.6 5.0 5.1 6.6 5.6 4.3 4.6 13.4 6.4 9.8 6.9 6.1 29.7 5.2 5.0 7.1 6.8 2.7 5.5 5.8 4.9 34.2 5.9 4.9 10.0 6.0 5.2 7.5 23.6 2.7 16.3 4.2 6.6 11.6 5.0 4.4 4.9 2.5 3.7 7.8 34.5 2.7 3.2 9.2 11.2 9.2 5.8 9.4 7.4 1.3 8.7 6.0 8.5 9.7 2.9 6.5 11.4 5.9 3.3 2.8 5.2 4.7 0.8 3.7 5.3 8.0 6.9 12.3 3.6 0.7 7.8 4.8 4.2 1.3 3.9 5.5 6.4 4.4 11.3 5.4 1.7 2.9 9.6 2.3 4.8 5.0 1.2 5.8 2.5 10.3 11.2 5.0 3.2 12.3 6.3 13.6 6.9 8.7 3.6 14.9 5.3 5.7 3.1 2.5 8.1 7.6 3.5 10.5 1.9 5.7 10.4 7.7 3.4 6.8 5.0 4.3 2.5 4.8 7.5 21.4 1.7 5.7 6.6 2.7 1.1 3.2 1.5 0.7 1.0 1.4 1.2 1.3 0.6 2.1 1.3 1.8 5.0 1.0 0.7 1.1 1.4 0.5 5.1 5.6 13.4 6.4 5.8 4.9 6.0 5.2 6.6 3.2 5.8 9.7 4.9 9.6 10.3 27.1 9.1 2.7 8.6 3.1 10.8 27.3 5.5 4.8 6.0 4.3 9.7 16.5 22.9 8.6 9.3 11.8 56.7 5.3 19.3 9.8 10.0 7.7 14.3 7.6 20.5 11.0 4.1 7.4 13.3 8.4 2.5 23.3 7.5 1.8 3.9 25.2 22.0 38.6 20.3 5.0 4.2 52.4 8.4 4.4 1.8 15.9 13.2 8.6 30.9 22.1 20.6 5.3 61.4 7.9 7.2 12.4 715.5 2.4 9.1 17.9 0.0 13.6 6.3 28.5 24.5 5.8 3.8 6.2 12.2 10.4 33.4 6.3 DNASE1L2 DNAS1L2 ENSG00000167968 "Deoxyribonuclease 1 like 2" Q92874 16 2235816-2238711 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 45.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Excitatory neurons: 2.5;Inhibitory neurons: 2.6;Ionocytes: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044714 Uncertain Mitochondria "Secreted in other tissues" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA044714: AB_10962870" "unprognostic (9.88e-2)" "unprognostic (1.11e-3)" "unprognostic (6.80e-4)" "unprognostic (4.29e-2)" "unprognostic (2.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (2.50e-1)" "unprognostic (2.72e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-3)" "unprognostic (2.17e-2)" "unprognostic (4.67e-4)" "unprognostic (1.40e-4)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.94e-4)" 0.9 1.1 4.8 0.4 5.2 0.5 1.2 7.3 8.4 1.8 2.0 1.0 0.5 1.1 0.2 0.9 1.2 0.3 0.9 4.2 4.5 4.6 1.7 0.9 0.4 6.1 4.5 2.0 1.9 0.1 4.7 0.7 6.4 2.3 0.1 1.1 0.8 0.1 0.7 45.8 1.0 0.1 3.7 2.6 1.0 1.5 4.9 0.6 6.0 0.1 0.8 0.9 1.6 7.6 1.4 2.9 1.2 1.3 1.0 0.5 5.0 0.5 0.3 1.1 0.6 3.2 3.0 1.9 1.5 0.1 0.4 0.5 0.4 0.2 0.1 3.8 2.8 0.8 5.6 0.7 0.1 0.9 3.0 0.6 1.0 0.8 0.2 1.1 0.2 2.1 2.7 2.8 0.4 3.4 2.7 5.6 1.2 0.4 1.9 5.0 1.4 2.7 0.6 0.6 2.5 1.3 0.7 1.1 2.1 0.3 4.5 2.0 0.1 2.4 3.1 1.4 1.0 6.8 3.5 1.8 0.8 1.8 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.8 5.2 7.3 8.4 4.2 4.5 6.1 4.5 6.4 3.7 4.9 7.6 0.2 0.0 0.6 2.9 0.1 0.1 0.1 0.4 0.0 0.7 0.7 0.5 0.7 1.5 0.1 0.0 0.0 0.1 0.2 0.5 0.0 0.1 0.1 0.2 1.0 0.3 0.0 0.0 2.5 0.0 0.1 0.1 1.1 0.4 0.0 0.6 0.4 0.4 0.1 1.7 2.6 0.1 4.1 0.0 0.0 0.1 0.6 0.1 0.0 1.0 0.1 0.9 0.0 1.0 1.8 0.0 0.1 0.0 0.5 0.2 0.8 0.1 0.1 1.8 0.0 0.0 0.2 0.1 0.5 0.0 0.1 0.0 0.2 0.3 0.3 0.1 DNASE1L3 "DNAS1L3, LSD" ENSG00000163687 "Deoxyribonuclease 1 like 3" Q13609 3 58192257-58214697 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Necrosis" "Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "liver: 271.4;lymphoid tissue: 263.5" "Cell type enriched" "Detected in many" 6 "Hepatic stellate cells: 1670.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 424.7" "Lineage enriched" "Detected in many" 20 "dendritic cells: 424.7" "Cell line enhanced" "Detected in some" "BEWO: 1.9;Karpas-707: 1.1;RPMI-8226: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019955 Approved "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA019955: AB_1847805" "unprognostic (7.49e-3)" "unprognostic (3.08e-3)" "unprognostic (9.75e-3)" "unprognostic (3.92e-3)" "unprognostic (2.93e-3)" "unprognostic (1.01e-2)" "prognostic favorable (1.20e-6)" "unprognostic (4.74e-4)" "unprognostic (2.10e-1)" "unprognostic (9.71e-2)" "unprognostic (1.91e-3)" "unprognostic (6.95e-2)" "prognostic favorable (1.06e-7)" "unprognostic (7.57e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (5.64e-3)" 20.6 41.0 0.6 38.0 0.5 2.9 10.3 1.5 0.7 4.4 5.4 31.4 29.7 1.7 1.5 16.9 2.8 7.9 14.7 0.6 0.5 47.7 271.4 18.0 38.7 0.6 0.5 1.1 1.1 1.7 20.3 7.1 0.8 1.8 42.2 0.5 8.7 1.4 1.0 4.5 42.5 3.5 0.5 263.5 5.9 3.8 0.8 22.6 16.5 0.3 54.0 12.0 9.4 1.2 0.0 0.2 0.1 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.3 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.0 0.2 1.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 2.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.3 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 20.4 0.1 0.1 40.4 20.7 0.1 0.0 0.6 0.5 0.2 424.7 0.0 3.4 0.6 0.5 1.5 0.7 0.6 0.5 0.6 0.5 0.8 0.5 0.8 1.2 126.6 0.0 9.8 0.3 25.7 9.2 0.3 1.1 12.0 0.1 0.9 1.4 1.2 35.8 2.0 0.0 0.0 0.1 76.3 0.5 3.9 0.0 1.9 0.4 0.2 239.9 0.0 85.5 0.1 0.4 1.2 6.1 0.0 0.8 1.3 0.1 1670.9 27.1 0.5 1.7 0.1 0.2 0.0 127.1 144.3 3.2 4.1 18.6 3.6 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.2 0.3 0.1 3.3 0.0 0.2 0.0 0.3 1.3 0.3 0.2 59.3 16.3 0.3 3.8 2.6 0.0 1.0 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 137.9;parathyroid gland: 155.7;placenta: 134.1;prostate: 107.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.3;Proximal enterocytes: 291.1;Proximal tubular cells: 101.4;Syncytiotrophoblasts: 172.0" "Cancer enhanced" "Detected in all" "prostate cancer: 55.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.3" "Lineage enriched" "Detected in many" 10 "T-cells: 52.3" "Cell line enhanced" "Detected in many" "ASC diff: 194.4;ASC TERT1: 212.6;BJ hTERT+: 207.0;RPTEC TERT1: 263.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" NA NA 190000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" 13.3 3.1 0.2 5.3 0.2 0.6 8.4 0.1 0.6 10.9 0.1 14.6 107.0 3.6 4.0 3.0 7.4 6.7 3.4 0.2 0.1 94.9 57.2 16.0 5.8 0.2 0.2 3.5 3.5 155.7 0.1 134.1 0.3 107.3 16.9 0.1 84.5 23.5 1.5 5.7 137.9 3.0 0.1 11.2 7.6 1.3 0.8 12.4 5.0 3.9 4.4 5.7 3.5 0.4 0.2 0.2 1.0 0.0 194.4 212.6 0.6 37.7 207.0 10.9 37.2 38.0 1.0 0.0 13.6 71.0 30.2 1.1 0.4 0.0 6.2 12.3 0.0 0.0 0.0 57.1 77.0 0.0 0.0 22.0 0.1 66.3 0.5 9.1 6.6 0.7 0.0 0.0 3.6 0.0 3.6 0.5 2.0 1.3 72.7 0.0 0.0 0.6 263.3 0.0 0.1 0.4 0.0 0.0 0.0 4.4 0.0 0.3 37.0 21.8 1.1 0.7 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 6.6 0.0 52.3 0.2 16.2 10.7 1.2 0.0 15.7 6.6 0.4 5.3 0.0 4.0 2.0 4.7 0.2 0.2 0.1 0.6 0.2 0.1 0.2 0.2 0.3 0.1 0.8 0.4 10.8 6.4 26.0 0.3 2.1 4.1 0.4 0.1 0.0 1.8 0.2 0.8 3.3 12.8 2.8 14.7 10.4 140.3 10.4 27.4 1.9 3.0 15.0 2.3 7.1 9.4 55.2 0.4 31.6 0.0 59.1 35.3 2.0 68.0 13.9 5.3 9.3 34.5 14.5 0.0 6.3 16.4 0.0 0.9 7.6 7.9 0.0 4.8 5.4 3.7 1.1 0.0 1.0 2.5 0.7 1.4 23.8 0.0 2.1 32.7 291.1 101.4 2.2 0.1 0.0 2.1 1.5 4.0 1.1 0.1 4.1 172.0 25.8 29.2 29.1 0.3 DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110546-137115177 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 997.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 232.0;THP-1: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted - unknown location" NA NA 1600000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "CAB025541: , HPA021282: AB_1847673, HPA059381: AB_2683999" "unprognostic (1.15e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (6.07e-6)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (8.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.10e-2)" "unprognostic (2.28e-2)" "unprognostic (5.71e-3)" "prognostic favorable (8.31e-5)" "unprognostic (7.99e-2)" "unprognostic (1.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" 60.2 98.8 42.1 28.0 43.2 45.8 56.8 43.4 64.9 45.4 83.6 65.3 28.4 46.3 16.7 46.0 53.6 31.3 116.4 43.8 52.0 58.7 70.0 57.3 41.7 53.4 48.0 37.7 82.8 54.3 112.3 26.7 45.7 81.1 7.3 8.0 92.3 46.2 52.8 56.6 51.7 12.8 45.6 79.0 69.4 75.3 48.3 19.8 83.7 21.4 14.4 59.3 48.0 49.2 28.0 43.1 3.5 3.6 51.1 40.5 5.7 42.2 66.2 26.6 17.4 41.0 22.2 56.2 44.4 27.2 1.2 60.3 30.7 8.2 1.3 54.8 2.1 26.4 63.6 1.3 113.5 69.1 135.5 50.0 31.7 11.6 24.1 38.3 35.1 65.8 57.5 41.2 18.0 76.4 35.7 65.7 14.8 99.9 42.8 52.8 0.5 232.0 43.3 30.5 67.7 46.7 47.8 122.6 118.9 0.8 43.5 218.1 44.1 67.4 23.5 43.4 29.5 51.7 31.8 14.9 80.9 41.1 31.1 40.2 194.8 59.2 148.8 176.2 151.8 86.6 131.4 127.9 190.6 83.4 117.1 106.2 12.0 95.0 110.6 276.6 173.6 204.1 42.1 43.2 43.4 64.9 43.8 52.0 53.4 48.0 45.7 45.6 48.3 49.2 80.5 54.5 80.9 54.9 96.8 67.0 103.2 109.2 59.7 74.5 90.3 82.2 66.5 94.4 76.8 53.3 35.5 55.2 129.2 28.2 37.2 121.0 288.7 35.9 40.7 58.2 88.1 35.9 31.4 68.1 115.3 97.2 33.6 47.3 74.3 178.7 64.6 77.1 315.7 121.1 27.9 32.3 107.8 171.7 106.2 997.8 155.4 150.1 167.2 9.4 165.5 123.9 122.6 16.6 26.4 58.2 54.3 169.2 190.2 108.5 97.3 84.9 75.4 83.6 52.6 57.4 58.4 106.2 46.2 47.3 64.9 51.4 115.4 19.0 43.1 90.4 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DRAXIN "C1orf187, FLJ34999, Neucrin" ENSG00000162490 "Dorsal inhibitory axon guidance protein" Q8NBI3 1 11691710-11725857 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 3.9" "Cell type enhanced" "Detected in some" "dendritic cells: 5.5;NK-cells: 3.1;T-cells: 4.6" "Group enriched" "Detected in some" 6 "glioma: 5.1;testis cancer: 2.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.5" "Cell line enriched" "Detected in some" 4 "NTERA-2: 27.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA014302 Uncertain "Secreted in brain" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 63: NK-cells & T-cells - Immune response" "HPA014302: AB_1853084" "unprognostic (5.28e-2)" "unprognostic (2.73e-1)" "unprognostic (6.58e-2)" "unprognostic (4.95e-2)" "unprognostic (2.51e-1)" "unprognostic (1.85e-1)" "unprognostic (1.37e-2)" "unprognostic (1.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.51e-2)" "unprognostic (7.47e-2)" "unprognostic (5.16e-6)" "unprognostic (4.65e-2)" "unprognostic (1.15e-1)" "unprognostic (8.52e-2)" "unprognostic (5.08e-1)" 0.0 0.0 1.6 0.2 1.4 0.5 0.0 1.1 1.3 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 1.2 1.0 0.0 0.0 0.1 0.2 2.7 0.6 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.7 0.0 0.1 0.2 0.1 0.0 0.4 0.1 0.0 0.3 3.9 0.0 0.1 0.0 0.1 0.0 0.0 1.3 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.6 0.0 0.9 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 5.7 0.0 0.2 0.0 0.1 0.0 0.2 2.1 0.3 27.9 0.0 0.1 6.4 0.2 0.0 0.0 0.0 1.8 0.7 0.1 0.0 0.1 4.6 0.0 0.2 0.2 0.1 1.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.4 2.5 0.3 0.1 0.5 0.1 0.2 0.1 0.1 0.3 0.0 0.2 0.2 0.2 0.8 0.2 0.2 0.1 0.2 0.1 1.6 1.4 1.1 1.3 1.2 1.0 2.7 0.6 0.5 0.4 3.9 1.3 0.1 0.0 0.5 0.0 1.2 0.5 2.9 0.6 0.0 0.7 0.4 0.4 1.1 1.5 0.1 0.0 2.1 0.1 5.5 0.1 0.0 0.1 0.7 0.4 0.4 0.6 0.0 0.0 0.4 0.2 0.2 0.6 0.0 0.4 1.3 0.1 1.1 0.2 0.4 0.0 0.5 0.7 0.0 0.8 1.9 2.1 0.6 1.2 1.8 0.0 0.3 0.2 3.1 1.5 0.4 0.2 0.2 0.0 1.5 2.1 0.0 0.1 0.0 0.7 0.0 2.3 0.7 0.6 1.7 0.0 0.3 0.0 4.6 0.1 0.1 2.2 DSPP "DFNA39, DGI1, DMP3" ENSG00000152591 "Dentin sialophosphoprotein" Q9NZW4 4 87608529-87616873 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Deafness, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036230 Uncertain "Secreted in other tissues" NA NA 27000 "HPA036230: AB_10672239" "unprognostic (2.34e-1)" "unprognostic (1.08e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 ECRG4 "augurin, C2orf40" ENSG00000119147 "ECRG4 augurin precursor" Q9H1Z8 2 106063246-106078155 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 225.3" "Cell type enhanced" "Detected in some" "Adipocytes: 87.6;Fibroblasts: 25.3;Smooth muscle cells: 19.1" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 72.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 8.5;naive CD8 T-cell: 7.2" "Lineage enriched" "Detected in single" 83 "T-cells: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008546 Uncertain "Secreted to blood" NA NA 330000 "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: Fibroblasts - ECM organization" "HPA008546: AB_2066524" "prognostic favorable (4.58e-4)" "unprognostic (3.91e-1)" "unprognostic (2.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.61e-3)" "unprognostic (6.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (1.36e-2)" "unprognostic (1.06e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (9.11e-3)" "unprognostic (1.30e-4)" 66.7 27.6 5.3 1.1 6.0 0.0 49.6 9.6 5.3 73.8 225.3 47.6 5.3 24.6 28.4 20.2 47.5 9.4 25.7 12.0 13.0 47.1 3.2 27.6 1.7 14.9 21.5 13.2 5.9 0.7 96.2 8.5 15.4 55.1 5.6 0.1 20.4 101.8 10.3 14.1 19.2 9.0 19.4 25.8 165.8 27.0 12.2 2.8 101.1 6.9 0.3 79.6 58.2 11.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 2.0 1.3 0.0 0.0 8.5 7.2 0.0 0.0 0.0 0.0 0.8 1.4 5.3 6.0 9.6 5.3 12.0 13.0 14.9 21.5 15.4 19.4 12.2 11.7 87.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 84.3;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cell line enhanced" "Detected in many" "EFO-21: 5.2;Hep G2: 17.9;OE19: 5.1;RPMI-8226: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Lipid droplets" "HPA037972: AB_2675761, HPA037973: AB_2675762" "unprognostic (3.76e-2)" "unprognostic (8.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.59e-3)" "unprognostic (7.85e-2)" "unprognostic (1.25e-4)" "unprognostic (4.33e-4)" "unprognostic (5.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "prognostic favorable (1.04e-9)" "unprognostic (8.63e-4)" "unprognostic (7.64e-2)" "unprognostic (9.85e-2)" "unprognostic (2.79e-1)" 4.2 8.5 2.4 0.7 3.0 0.1 2.8 2.2 2.6 4.9 5.2 2.6 0.5 3.0 3.2 1.5 3.8 2.0 10.4 2.1 2.4 3.7 2.1 3.2 0.8 3.2 2.8 4.9 4.2 9.7 1.3 1.8 3.0 3.4 1.1 0.3 2.2 2.2 1.7 4.2 1.1 2.1 2.3 1.4 3.8 1.2 3.1 1.2 6.0 2.0 0.6 2.3 3.9 4.6 0.0 0.6 0.3 2.8 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 5.2 0.2 0.2 0.5 3.8 1.4 0.0 0.0 4.5 0.0 0.0 17.9 1.0 0.0 1.1 1.8 1.3 0.0 0.9 0.0 0.5 3.5 0.0 4.9 0.0 1.2 0.0 0.0 2.8 5.1 0.3 0.0 1.2 6.0 0.1 0.0 1.5 0.0 0.1 0.3 0.1 2.0 0.3 0.1 0.5 1.7 2.2 2.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.8 0.0 0.0 0.1 2.4 3.0 2.2 2.6 2.1 2.4 3.2 2.8 3.0 2.3 3.1 4.6 3.3 3.2 0.5 21.2 0.3 3.8 2.6 2.0 6.8 0.2 0.9 1.5 12.1 0.0 1.1 5.5 0.0 0.2 0.1 1.0 0.0 1.3 21.3 4.6 1.2 2.2 1.8 0.0 17.9 1.3 0.2 6.0 5.6 12.2 0.0 0.5 11.0 1.2 4.1 0.0 9.6 0.6 0.0 4.8 1.2 9.2 4.7 2.8 1.8 84.3 0.1 1.3 0.0 30.2 45.9 1.1 0.1 2.2 0.2 2.3 0.4 3.1 1.3 0.1 6.6 10.7 5.4 1.7 3.5 3.2 4.1 0.0 2.1 0.4 0.9 1.5 EDDM13 ENSG00000267710 "Epididymal protein 13" A0A1B0GTR0 19 56272748-56310454 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 63 "epididymis: 98.8" "Cell type enhanced" "Detected in some" "Adipocytes: 1.5;Alveolar cells type 2: 1.3;Breast myoepithelial cells: 2.2;dendritic cells: 1.1;Endothelial cells: 2.2;granulocytes: 1.3;Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.08e-4)" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (1.40e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (3.22e-3)" "unprognostic (1.33e-1)" "unprognostic (5.23e-3)" "unprognostic (2.93e-2)" "unprognostic (9.16e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (3.84e-2)" "unprognostic (4.20e-1)" 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 98.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.1 0.1 0.1 0.2 0.0 0.1 0.1 1.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.7 0.6 2.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.4 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 EDDM3A "FAM12A, HE3-ALPHA" ENSG00000181562 "Epididymal protein 3A" Q14507 14 20745887-20748380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "epididymis: 636.1" "Cell type enriched" "Detected in some" 26 "Collecting duct cells: 29.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049952 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA049952: AB_2680970" "unprognostic (1.42e-1)" "unprognostic (9.88e-2)" "unprognostic (8.56e-3)" "unprognostic (2.10e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 636.1 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 35.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 29.5 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 EDDM3B "FAM12B, HE3-BETA" ENSG00000181552 "Epididymal protein 3B" P56851 14 20768404-20770948 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 279 "epididymis: 2563.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;NB-4: 2.6" "Not detected" "Not detected" HPA001323 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA001323: AB_1848377" "unprognostic (2.40e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2563.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EDIL3 DEL1 ENSG00000164176 "EGF like repeats and discoidin domains 3" O43854 5 83940554-84384880 "Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 256.8" "Group enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 561.4;Oligodendrocytes: 2119.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 547.0;LHCN-M2: 169.8;TIME: 203.3;U-2 OS: 163.2;U-87 MG: 112.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020415 Approved "Secreted to blood" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA020415: AB_2670434" "unprognostic (9.93e-3)" "unprognostic (2.38e-1)" "unprognostic (2.71e-2)" "unprognostic (8.63e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (9.19e-2)" "unprognostic (6.64e-3)" "unprognostic (2.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.52e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.28e-3)" 13.9 21.7 55.3 13.6 126.6 0.2 6.2 93.9 105.1 17.5 7.6 37.0 17.0 26.8 44.9 17.0 10.9 34.0 20.6 68.1 90.1 10.7 0.7 20.9 0.8 118.1 89.3 10.1 3.4 4.2 2.9 4.6 121.0 13.5 38.4 40.2 3.9 22.1 0.8 9.7 26.2 25.8 99.1 3.2 19.7 2.3 82.3 0.3 4.0 0.7 3.6 15.7 9.5 256.8 0.1 1.5 1.4 0.0 3.7 0.2 0.1 4.8 0.0 12.6 16.9 0.0 21.2 0.0 0.1 0.1 8.8 19.6 0.0 0.8 9.3 0.1 9.2 0.0 54.5 0.0 99.9 1.0 0.2 25.6 2.6 61.0 8.5 547.0 21.7 0.0 0.0 0.3 169.8 0.1 0.1 0.3 8.7 0.0 39.4 0.1 41.4 0.1 28.2 0.0 4.5 0.5 0.0 0.3 0.1 26.1 0.2 0.2 203.3 60.8 163.2 2.1 56.6 1.6 0.0 0.1 112.6 0.1 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 126.6 93.9 105.1 68.1 90.1 118.1 89.3 121.0 99.1 82.3 256.8 3.1 9.6 6.0 14.0 0.1 12.1 1.7 13.7 14.8 179.2 0.3 11.7 13.3 0.0 4.5 3.7 2.1 0.3 0.1 5.9 0.0 0.1 32.8 0.4 7.2 10.4 22.9 0.0 219.9 0.0 0.0 34.8 0.0 0.3 5.7 1.3 1.4 0.1 0.3 5.0 216.5 9.2 2.0 0.0 3.3 19.8 2.5 0.3 3.6 32.8 0.0 5.4 0.0 561.4 2119.7 0.4 8.1 3.8 0.0 0.9 0.0 0.9 1.2 11.6 6.6 0.2 40.2 1.9 1.5 9.3 16.1 0.4 0.6 16.2 8.4 0.7 EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 749.7;Ductal cells: 316.3;Glandular and luminal cells: 289.7;Pancreatic endocrine cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cell line enhanced" "Detected in many" "EFO-21: 660.4;HUVEC TERT2: 446.8;T-47d: 137.5;TIME: 334.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" 44.6 1.8 14.7 7.3 13.8 4.7 23.6 13.6 18.2 6.2 9.7 10.6 10.4 7.0 6.3 12.1 9.4 13.5 7.8 12.6 12.2 7.7 3.1 36.6 5.6 15.1 13.6 2.6 9.6 1.4 1.1 18.5 15.2 5.5 14.5 1.0 12.1 8.9 7.6 11.8 9.8 11.3 13.1 12.3 10.4 4.7 15.7 1.7 3.4 6.4 2.4 9.9 5.9 14.2 10.3 57.6 1.1 0.1 0.3 0.2 0.2 18.2 16.0 15.0 12.4 74.6 8.6 0.0 660.4 7.2 9.2 5.4 0.0 10.6 11.0 0.8 0.0 0.0 2.1 2.3 0.8 0.0 0.0 0.4 6.2 3.0 2.1 4.7 446.8 0.0 0.0 0.0 56.8 1.6 0.2 0.3 0.6 10.4 0.7 0.2 5.1 0.1 35.3 9.4 0.6 0.0 1.8 53.1 0.1 117.2 137.5 0.8 334.3 37.1 30.1 0.7 23.5 0.3 0.4 1.3 0.3 0.0 1.6 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.0 0.0 14.7 13.8 13.6 18.2 12.6 12.2 15.1 13.6 15.2 13.1 15.7 14.2 190.7 173.1 23.8 2.9 0.8 189.9 749.7 99.9 151.4 0.2 68.7 26.8 2.2 8.6 110.6 38.6 0.0 1.8 0.8 189.7 3.9 316.3 13.3 187.2 16.3 236.8 15.6 2.7 3.6 218.9 0.4 9.0 22.4 289.7 1.3 0.8 169.2 1.8 1.8 1.7 3.0 43.8 12.2 5.0 6.7 19.8 5.6 5.3 8.8 6.5 10.9 0.3 0.0 3.5 0.6 268.5 145.7 0.4 0.4 185.8 119.6 8.3 27.4 0.4 6.6 1.8 21.8 1.0 0.6 53.7 64.5 0.8 9.7 0.1 196.6 141.8 EDN2 ET2 ENSG00000127129 "Endothelin 2" P20800 1 41478775-41484683 "Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.1;esophagus: 20.8;vagina: 32.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 239.7;Basal respiratory cells: 137.3;Club cells: 146.1;Collecting duct cells: 69.9;Prostatic glandular cells: 62.5;Proximal enterocytes: 91.7" "Cancer enhanced" "Detected in many" "cervical cancer: 24.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;EFO-21: 35.9;HeLa: 13.0;SCLC-21H: 16.8;SK-BR-3: 41.2;U-2 OS: 15.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA028459 Uncertain Approved Cytosol "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA028459: AB_10602490" "unprognostic (2.71e-2)" "unprognostic (5.64e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.47e-2)" "unprognostic (3.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-1)" "unprognostic (5.44e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.81e-4)" "unprognostic (5.59e-2)" "unprognostic (1.28e-2)" "unprognostic (8.47e-2)" "unprognostic (1.76e-1)" "unprognostic (6.14e-2)" "unprognostic (3.85e-1)" 0.3 0.1 0.0 0.0 0.0 0.1 3.1 0.0 0.0 26.1 1.0 1.9 3.9 3.1 4.7 20.8 1.6 0.2 1.4 0.1 0.0 7.4 1.2 3.7 0.0 0.1 0.1 0.1 2.4 0.0 2.1 0.0 0.1 7.5 0.9 0.2 8.0 0.5 0.2 15.0 17.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.5 0.0 0.3 2.4 32.7 0.1 0.2 0.8 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.8 13.8 0.0 35.9 0.0 0.0 1.7 0.0 0.1 0.0 4.2 0.0 0.0 13.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 0.8 0.4 0.0 0.0 1.3 8.4 9.4 0.9 16.8 0.0 0.3 41.2 0.0 0.9 0.8 0.0 0.0 0.0 15.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 6.4 1.5 0.0 0.0 30.3 239.7 137.3 8.6 0.1 2.5 1.3 0.7 2.8 146.1 69.9 0.0 0.2 0.1 23.3 0.0 8.8 0.0 36.9 0.5 0.6 1.8 0.0 0.0 1.0 0.0 1.8 3.1 6.5 0.0 0.3 0.0 0.2 0.0 0.0 0.0 4.2 38.7 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 10.9 2.7 0.0 0.1 62.5 91.7 1.6 20.9 0.0 0.0 0.4 3.5 0.0 0.2 2.4 29.1 0.0 0.7 0.8 8.2 45.2 EDN3 ET3 ENSG00000124205 "Endothelin 3" P14138 20 59300443-59325992 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Deafness, Disease variant, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 53.1;salivary gland: 68.3;vagina: 106.5" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 99.6;Distal enterocytes: 86.6;Paneth cells: 72.4;Proximal enterocytes: 93.0;Skeletal myocytes: 110.0;Squamous epithelial cells: 69.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 30900 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 37: Intestine - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (4.64e-3)" "unprognostic (7.87e-2)" "unprognostic (7.49e-2)" "unprognostic (2.88e-3)" "prognostic favorable (1.73e-4)" "unprognostic (1.58e-1)" "unprognostic (1.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.01e-2)" "unprognostic (4.08e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-2)" "unprognostic (1.55e-1)" "unprognostic (6.40e-2)" 0.1 2.3 4.9 2.0 5.1 0.0 7.8 4.8 5.9 53.1 3.3 20.2 42.0 5.2 6.1 20.6 0.2 0.4 0.1 4.9 4.5 0.2 0.0 0.4 0.2 5.5 7.3 1.3 8.8 0.3 44.7 0.2 8.6 5.6 18.8 2.0 68.3 0.5 1.5 1.9 40.6 3.0 5.0 7.9 1.7 1.2 11.2 3.2 24.2 2.4 0.1 0.1 106.5 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.9 5.1 4.8 5.9 4.9 4.5 5.5 7.3 8.6 5.0 11.2 3.9 0.1 9.6 0.5 0.0 0.0 0.4 5.1 0.0 99.6 0.1 1.7 21.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 86.6 0.0 0.3 0.0 1.6 11.2 0.4 1.2 0.0 0.8 0.0 0.3 2.6 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.6 0.0 0.0 0.4 0.0 0.0 0.5 0.0 20.6 0.0 0.4 0.0 0.0 0.0 0.2 72.4 1.9 1.2 0.2 93.0 0.0 0.0 0.4 0.0 110.0 0.4 0.1 0.8 69.2 0.3 0.0 0.3 0.1 15.9 0.3 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 122.8;Leydig cells: 93.5;Muller glia cells: 84.8;Peritubular cells: 107.2;Smooth muscle cells: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 159.7;fHDF/TERT166: 232.6;HSkMC: 155.3;hTERT-RPE1: 159.1;LHCN-M2: 134.5;U-138 MG: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" 38.4 18.0 19.8 13.8 21.1 2.8 29.5 18.8 26.7 46.6 22.1 39.6 9.3 55.2 8.3 12.8 35.8 33.5 61.6 19.1 20.4 26.8 7.0 32.1 9.1 24.9 20.0 47.0 19.9 26.8 15.2 22.4 21.4 31.1 6.5 5.9 17.4 35.2 21.2 14.9 16.2 32.3 20.3 16.1 20.6 8.2 21.4 5.6 39.1 22.0 5.0 33.1 30.7 19.1 0.5 0.2 2.1 47.3 54.3 108.0 0.8 125.8 159.7 48.1 44.8 0.0 4.3 0.7 9.3 232.6 0.7 0.9 0.0 1.3 12.1 5.4 0.1 1.1 3.2 8.0 89.1 0.0 0.4 155.3 0.4 18.9 1.0 159.1 28.5 1.0 0.3 8.0 134.5 0.4 0.2 20.7 1.6 0.2 0.6 0.4 0.3 3.2 1.6 0.6 0.7 14.1 0.2 1.3 1.5 6.6 1.5 10.0 64.6 114.2 24.7 52.6 0.6 10.9 0.7 0.3 42.6 0.8 19.7 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.2 19.8 21.1 18.8 26.7 19.1 20.4 24.9 20.0 21.4 20.3 21.4 19.1 30.8 35.3 7.4 29.0 1.5 13.5 38.9 33.9 8.6 7.7 10.2 27.6 46.0 15.7 11.4 18.4 0.0 2.4 2.3 0.3 7.9 28.7 15.6 3.4 57.1 27.9 0.0 0.4 1.1 0.2 3.9 122.8 2.6 4.1 0.0 74.3 42.8 1.8 9.8 6.7 2.9 0.3 4.1 3.5 19.1 33.3 93.5 3.0 24.9 9.4 0.7 84.8 2.1 9.5 1.6 2.6 0.1 107.2 1.4 30.1 0.2 21.2 9.0 4.8 39.5 41.1 113.2 35.9 3.3 1.1 10.1 5.9 2.4 78.5 0.3 14.2 EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 472.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 942.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.4;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 266.5;HaCaT: 95.5;SiHa: 156.9;SK-BR-3: 227.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" NA Yes 2800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" 43.2 24.0 25.6 4.9 30.0 1.3 64.7 27.2 33.9 31.7 21.8 42.5 57.9 23.7 28.5 54.7 23.2 24.5 47.1 25.5 25.9 73.8 472.8 86.7 8.1 31.0 29.0 17.5 53.6 29.7 19.5 109.9 29.8 79.5 51.6 7.8 66.6 22.1 18.5 123.1 69.3 13.4 27.8 8.6 40.7 4.1 27.6 21.0 79.9 38.6 12.5 36.9 55.5 35.2 15.1 5.9 0.9 11.5 2.1 0.1 266.5 0.0 0.5 0.2 0.3 13.9 32.0 0.0 26.3 0.0 9.0 95.5 6.6 35.3 0.2 9.8 2.2 0.1 19.0 76.1 0.9 0.2 1.5 4.9 84.5 0.0 30.2 7.3 53.6 0.9 2.8 0.3 0.0 52.2 0.3 1.1 1.7 52.3 17.7 6.1 1.5 9.3 66.4 22.4 9.8 14.2 156.9 227.1 6.0 48.8 51.1 0.0 6.7 0.1 9.1 0.6 1.5 2.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 1.0 0.7 0.0 0.3 11.4 5.9 0.4 0.4 0.0 0.0 0.0 1.6 25.6 30.0 27.2 33.9 25.5 25.9 31.0 29.0 29.8 27.8 27.6 35.2 116.8 198.7 113.1 0.7 2.3 127.7 103.7 91.6 327.8 3.0 198.3 151.9 47.8 95.8 101.2 18.4 0.0 195.6 4.4 265.0 13.7 130.1 0.3 100.4 19.1 148.9 18.6 4.0 0.7 63.9 942.6 23.2 124.9 163.5 6.3 0.1 106.4 133.2 28.2 5.0 0.8 114.1 101.7 4.3 19.5 0.7 4.7 4.2 62.2 2.8 0.6 5.7 0.0 3.5 28.7 73.9 205.5 0.4 4.1 197.8 238.6 34.5 54.5 1.1 0.0 6.5 35.9 0.8 2.6 253.2 217.8 254.2 7.5 1.3 95.9 135.9 EFNA4 "EPLG4, LERK4" ENSG00000243364 "Ephrin A4" P52798 1 155063737-155069553 "Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 30.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.1;Theca cells: 73.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB021350 Uncertain "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB021350: " "unprognostic (4.65e-2)" "unprognostic (8.07e-2)" "unprognostic (3.43e-2)" "unprognostic (7.04e-2)" "unprognostic (7.91e-2)" "unprognostic (4.81e-1)" "prognostic unfavorable (1.00e-5)" "unprognostic (1.37e-2)" "unprognostic (3.89e-2)" "unprognostic (6.17e-2)" "unprognostic (2.87e-2)" "unprognostic (7.97e-3)" "prognostic unfavorable (3.14e-4)" "prognostic favorable (3.60e-5)" "unprognostic (3.35e-2)" "unprognostic (1.97e-1)" "unprognostic (6.29e-2)" 3.7 12.0 3.2 4.5 3.3 1.3 9.4 3.3 3.4 11.1 4.5 11.7 10.5 6.5 12.4 18.6 4.9 5.2 3.5 3.3 3.0 6.9 8.3 4.5 5.1 3.6 3.4 9.9 5.7 7.9 2.5 4.5 3.5 9.1 12.1 0.9 13.1 4.3 1.3 30.2 10.7 4.3 3.4 6.5 5.9 2.3 3.3 3.8 6.2 1.8 7.3 4.8 14.2 3.5 11.4 8.5 20.4 30.4 11.8 7.5 17.0 5.1 9.6 9.7 9.0 12.5 18.5 14.6 28.2 5.1 7.7 26.2 12.3 7.6 3.9 6.9 3.7 1.4 7.7 17.8 4.3 3.3 22.0 4.5 23.2 4.9 5.7 8.4 19.7 11.9 6.2 9.5 5.5 25.2 7.5 8.3 37.6 43.3 17.5 26.0 8.1 14.3 15.2 9.6 4.9 22.3 10.1 37.1 4.5 14.7 24.3 10.2 10.2 5.8 17.0 11.7 7.8 9.7 11.0 14.6 5.5 7.8 5.9 0.1 10.1 7.3 7.7 9.2 8.0 22.9 8.5 8.8 8.3 17.3 11.8 8.1 10.9 3.9 13.7 25.2 8.9 6.6 3.2 3.3 3.3 3.4 3.3 3.0 3.6 3.4 3.5 3.4 3.3 3.5 2.5 0.0 6.3 2.0 9.0 25.1 8.6 21.2 19.4 0.2 20.7 15.6 1.3 8.6 12.1 16.5 0.0 9.2 12.3 23.9 1.9 32.4 0.1 4.9 4.5 6.8 3.0 2.1 0.2 14.0 86.1 8.4 3.6 6.6 1.3 15.6 5.7 3.6 12.8 0.0 0.2 18.7 8.2 6.3 6.8 0.4 7.8 5.3 17.8 1.0 5.9 5.6 4.1 0.0 0.8 21.5 37.0 5.7 2.2 21.2 38.3 4.4 6.5 0.2 0.0 1.7 6.0 0.5 4.1 15.4 32.7 9.9 7.2 73.3 28.3 10.8 EGFL6 MAEG ENSG00000198759 "EGF like domain multiple 6" Q8IUX8 X 13569601-13633575 "Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "placenta: 645.2" "Cell type enriched" "Detected in many" 8 "Fibroblasts: 214.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 4.3;NTERA-2: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001838 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA001838: AB_2666457" "unprognostic (1.66e-1)" "unprognostic (1.32e-2)" "unprognostic (9.15e-3)" "unprognostic (3.76e-3)" "unprognostic (1.77e-2)" "prognostic favorable (9.73e-4)" "unprognostic (4.13e-3)" "unprognostic (1.37e-1)" "unprognostic (5.19e-3)" "prognostic favorable (4.95e-4)" "unprognostic (2.39e-3)" "unprognostic (1.81e-1)" "unprognostic (1.14e-9)" "unprognostic (7.10e-2)" "unprognostic (3.21e-2)" "unprognostic (1.70e-1)" "unprognostic (1.82e-3)" 20.1 0.0 0.4 0.6 0.5 0.0 3.2 0.1 0.3 1.0 0.1 0.2 0.5 1.8 0.0 4.3 2.2 1.1 0.3 0.3 1.2 0.7 0.0 25.6 0.3 0.9 1.3 0.3 1.2 0.6 2.6 645.2 0.4 1.1 0.3 2.3 0.4 0.1 0.0 0.5 0.4 0.5 1.6 0.3 1.3 0.3 0.4 0.2 0.3 1.6 1.6 10.7 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.1 0.3 0.3 1.2 0.9 1.3 0.4 1.6 0.4 0.2 1.3 0.0 2.0 0.0 0.0 1.0 1.2 22.0 1.2 6.3 0.1 0.5 0.4 0.0 11.9 0.0 0.0 12.4 0.0 0.5 0.0 0.0 0.3 4.2 5.6 6.0 0.0 0.0 0.3 0.0 9.8 214.7 0.0 3.7 0.0 0.0 0.0 0.0 17.3 0.0 2.0 0.1 4.1 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.4 1.0 0.0 0.0 23.9 0.1 1.1 14.9 0.4 26.4 0.9 4.9 0.1 3.7 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164595-32168281 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Granulosa cells: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 3.2;SK-MEL-30: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nuclear speckles" "HPA061173: AB_2684443" "unprognostic (7.13e-2)" "unprognostic (1.86e-1)" "unprognostic (6.79e-3)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (7.60e-4)" "unprognostic (3.42e-2)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (1.97e-1)" "unprognostic (7.60e-3)" "unprognostic (8.11e-3)" "unprognostic (1.07e-4)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" 13.3 7.2 3.8 0.5 3.5 1.1 13.6 3.6 5.7 23.4 4.1 19.8 0.6 10.0 0.8 12.3 16.3 3.0 14.2 3.9 3.9 16.3 7.4 9.4 0.3 3.8 3.9 31.2 5.1 0.4 8.2 2.9 3.7 16.9 0.5 0.0 7.9 1.4 3.8 12.8 8.8 0.3 3.8 7.9 10.2 4.4 4.1 0.6 8.7 2.5 0.2 13.5 17.2 3.8 0.2 0.1 0.4 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.5 0.0 0.3 3.2 0.0 0.0 0.3 0.0 0.4 0.2 0.1 0.0 0.2 0.7 0.5 0.0 0.0 0.6 1.0 1.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 3.4 0.0 1.0 0.7 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.5 3.6 5.7 3.9 3.9 3.8 3.9 3.7 3.8 4.1 3.8 1.2 6.4 4.1 0.0 0.3 1.5 0.6 0.3 4.6 1.5 0.5 0.3 0.1 0.0 1.6 1.8 2.1 0.8 0.6 0.2 0.0 0.4 0.1 1.0 1.9 1.7 0.0 1.7 0.0 0.2 0.4 1.5 4.6 1.3 0.0 10.4 3.3 0.3 0.2 0.0 0.0 1.1 0.0 0.6 1.6 0.2 3.7 0.7 0.0 0.0 0.0 0.9 3.1 0.0 0.0 0.3 0.2 1.2 2.1 0.7 0.4 0.1 1.6 1.5 0.0 2.0 1.5 0.5 0.4 4.0 2.3 0.8 0.9 1.5 1.3 0.5 EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 121.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 120.9;Early spermatids: 50.7;Late spermatids: 49.1;Leydig cells: 155.4;Sertoli cells: 85.5;Smooth muscle cells: 70.9" "Cancer enhanced" "Detected in all" "testis cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 10.2;HBEC3-KT: 12.6;hTERT-HME1: 16.4;HUVEC TERT2: 16.1;LHCN-M2: 37.0;U-2 OS: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA066577: " "unprognostic (2.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-3)" "unprognostic (1.08e-2)" "unprognostic (3.63e-3)" "unprognostic (6.31e-2)" "unprognostic (2.83e-1)" "unprognostic (2.08e-2)" "unprognostic (1.71e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "prognostic unfavorable (4.47e-5)" "unprognostic (7.02e-6)" "unprognostic (2.60e-1)" "unprognostic (9.90e-2)" "unprognostic (1.04e-2)" 41.7 19.8 2.0 2.8 2.5 0.2 47.1 1.9 2.3 15.6 3.5 6.1 1.9 5.6 6.8 4.0 8.2 4.9 26.2 1.5 2.4 6.9 4.7 2.9 14.2 3.2 4.2 23.7 3.1 4.0 5.8 51.6 3.6 14.2 3.2 66.7 6.9 20.6 72.0 5.9 4.7 6.7 1.6 9.8 3.4 15.0 3.6 20.4 9.0 121.2 9.1 7.7 13.0 2.5 3.2 0.0 6.5 0.2 0.8 0.2 0.0 2.9 0.0 0.5 0.1 0.0 0.0 0.1 10.2 0.1 0.1 0.0 0.0 12.6 0.0 0.0 1.6 0.0 6.1 0.0 2.8 0.0 0.1 5.4 0.0 0.1 16.4 0.0 16.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.3 3.9 0.0 3.7 0.1 1.3 0.0 0.2 0.0 0.1 15.6 0.6 0.2 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.5 1.9 2.3 1.5 2.4 3.2 4.2 3.6 1.6 3.6 2.5 11.4 0.0 0.0 0.3 0.0 2.7 0.3 0.0 0.0 1.3 2.4 9.8 2.6 0.0 0.0 0.0 120.9 0.3 0.4 0.0 3.9 0.5 50.7 0.2 3.2 5.4 0.0 0.0 0.6 1.0 0.5 17.8 0.0 0.3 0.0 1.6 1.4 0.0 0.7 0.0 0.9 0.0 0.0 0.0 4.2 49.1 155.4 0.6 5.4 1.9 0.0 3.4 0.0 1.0 0.1 1.3 0.0 30.9 0.0 0.2 0.0 6.5 0.0 33.1 85.5 22.0 70.9 9.8 3.3 0.3 2.0 0.5 0.4 23.5 0.0 0.3 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "bone marrow: 3894.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.7;Fibroblasts: 16.2;Langerhans cells: 11.1;Leydig cells: 6.2;Melanocytes: 7.2;Suprabasal keratinocytes: 7.4" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 4.0;neutrophil: 12.1" "Group enriched" "Detected in many" 9 "granulocytes: 12.1;monocytes: 4.0" "Cell line enriched" "Detected in some" 91 "THP-1: 3105.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015409, HPA066836, HPA073774" Enhanced "Secreted to blood" NA NA 370000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015409: AB_831596, HPA066836: AB_2685733, HPA073774: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 3.4 1.0 0.3 0.0 0.3 3894.9 3.4 0.1 0.7 0.5 0.2 2.0 0.4 1.0 0.0 1.1 1.4 0.1 4.0 0.3 0.2 0.7 3.3 19.4 0.6 0.1 0.2 0.5 0.5 0.0 1.2 0.8 0.1 2.9 0.0 0.0 2.4 0.1 1.5 5.4 1.8 0.1 0.1 42.6 1.4 0.4 0.2 6.3 3.1 0.0 0.0 2.1 1.0 0.2 2.0 0.1 0.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3105.0 0.0 0.0 0.1 0.0 1.3 0.0 0.2 0.8 0.0 34.0 0.0 0.0 4.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 27.2 0.3 0.3 0.1 0.7 0.3 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.9 0.0 0.0 0.0 0.3 8.7 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 0.0 4.2 0.1 0.0 1.3 16.2 0.0 0.1 0.0 0.0 0.7 0.9 0.2 0.0 0.1 0.0 0.0 3.4 11.1 0.0 6.2 1.1 7.2 0.0 0.9 0.0 1.0 0.0 0.1 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.2 0.0 0.0 7.4 0.0 0.7 0.2 0.0 0.0 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ELSPBP1 "E12, EDDM12, HE12" ENSG00000169393 "Epididymal sperm binding protein 1" Q96BH3 19 47994632-48025154 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "epididymis: 2828.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 22.0;Cone photoreceptor cells: 16.7;Early spermatids: 32.0;Horizontal cells: 18.5;Late spermatids: 28.8;Muller glia cells: 20.4;Rod photoreceptor cells: 120.5" "Cancer enhanced" "Detected in single" "melanoma: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HMC-1: 10.1;NB-4: 5.5" "Not detected" "Not detected" "HPA044256, HPA050341" Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA044256: AB_2678879, HPA050341: AB_2681097" "unprognostic (1.51e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2828.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 18.5 0.1 0.0 0.0 0.0 0.0 28.8 0.6 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 120.5 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EMC10 "C19orf63, HSM1, HSS1, INM02" ENSG00000161671 "ER membrane protein complex subunit 10" Q5UCC4 19 50476400-50490871 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 185.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 193.0;PC-3: 137.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053905, HPA062723" Approved "Secreted to blood" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA053905: AB_2682303, HPA062723: " "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (9.86e-3)" "unprognostic (1.65e-1)" "unprognostic (6.94e-2)" "unprognostic (8.38e-3)" "unprognostic (3.23e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-1)" "unprognostic (2.99e-1)" "prognostic favorable (4.39e-4)" "unprognostic (5.01e-2)" "prognostic favorable (6.64e-6)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" 24.3 63.9 29.1 11.4 41.5 19.7 27.6 38.4 38.2 34.1 46.7 36.1 23.8 38.8 15.3 36.0 32.0 13.5 50.7 27.2 29.4 76.3 63.0 32.1 9.7 38.8 35.0 49.6 55.2 44.3 106.4 9.5 36.0 38.3 7.1 8.7 55.7 16.9 185.8 31.7 36.0 6.6 32.7 27.8 47.8 45.6 36.0 6.9 82.4 9.0 6.8 31.0 27.3 49.5 66.2 80.1 3.0 30.8 8.8 10.8 0.8 62.9 11.4 5.4 5.9 0.7 44.4 21.6 0.8 11.3 9.9 55.1 3.7 10.3 2.0 84.2 193.0 4.6 33.9 0.0 14.7 19.1 123.2 13.3 11.3 5.6 4.3 5.2 13.5 18.5 42.7 44.9 11.3 46.0 30.3 0.6 0.3 26.0 137.6 51.7 9.7 71.7 25.0 59.2 48.5 107.9 92.5 29.6 36.1 3.6 31.0 34.8 26.2 3.8 83.1 23.0 34.4 49.5 132.7 17.9 24.8 13.2 30.8 6.2 6.9 8.1 5.0 5.6 4.3 6.4 5.3 5.3 5.3 8.5 6.2 6.0 3.0 3.1 4.3 7.0 4.7 5.2 29.1 41.5 38.4 38.2 27.2 29.4 38.8 35.0 36.0 32.7 36.0 49.5 30.3 64.1 111.1 15.7 65.6 29.7 53.4 60.9 31.3 82.3 72.5 53.8 11.3 81.5 64.0 69.9 81.3 129.5 71.0 103.6 23.5 181.8 177.7 52.1 49.4 46.0 212.2 21.7 7.9 112.3 155.0 46.6 71.9 79.8 53.2 80.3 55.6 79.4 133.8 37.0 11.8 117.7 59.0 109.2 36.7 39.1 69.0 67.7 83.6 9.4 103.1 101.2 90.6 44.2 78.3 114.4 144.9 115.1 80.2 66.4 158.2 66.8 28.6 71.7 6.6 93.3 43.7 18.0 56.2 50.3 31.3 151.0 67.4 78.5 130.5 66.5 EMID1 "EMI5, EMU1, hEmu1" ENSG00000186998 "EMI domain containing 1" Q96A84 22 29205896-29259597 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.5;lymphoid tissue: 54.8" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Granulosa cells: 32.7;Oligodendrocyte precursor cells: 51.8;Theca cells: 151.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 23.1;glioma: 7.8;ovarian cancer: 10.9;thyroid cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HEL: 28.8;NB-4: 102.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000592 Uncertain "Secreted in other tissues" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA000592: AB_1078737" "unprognostic (2.20e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-2)" "unprognostic (7.80e-3)" "unprognostic (2.40e-2)" "unprognostic (1.42e-1)" "unprognostic (3.46e-1)" "unprognostic (6.25e-3)" "unprognostic (3.75e-2)" "unprognostic (2.33e-1)" "unprognostic (5.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-1)" 2.6 29.0 34.5 4.2 35.0 14.8 2.5 27.7 49.5 6.5 24.4 5.7 5.1 10.0 1.7 1.3 10.4 4.8 2.3 36.8 29.4 15.0 3.3 13.0 7.5 30.1 30.4 7.0 14.0 12.4 2.0 4.9 28.3 6.1 3.4 0.3 3.6 3.9 0.8 6.3 8.3 2.3 27.0 54.8 7.7 2.3 27.8 4.8 13.2 0.3 2.3 4.9 2.2 32.4 0.0 0.2 4.9 10.5 0.0 0.0 0.7 0.0 0.0 0.4 0.3 5.7 0.7 0.0 4.7 0.1 0.0 0.0 2.5 0.1 0.0 11.5 8.6 28.8 0.1 1.1 0.7 4.1 2.2 0.3 0.2 0.2 0.0 0.0 0.0 6.4 2.5 0.0 0.0 8.0 0.2 102.0 1.1 0.1 0.4 0.0 0.2 11.3 0.0 0.1 13.2 6.3 0.4 0.1 0.2 0.8 4.2 5.4 0.0 0.0 8.0 0.0 0.1 0.5 0.0 0.0 0.0 14.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 34.5 35.0 27.7 49.5 36.8 29.4 30.1 30.4 28.3 27.0 27.8 32.4 0.4 0.0 2.5 92.1 0.1 2.8 1.0 0.1 0.0 1.7 5.3 3.9 0.7 4.3 0.6 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.2 10.8 22.6 6.2 0.0 18.5 5.6 1.3 0.1 11.8 0.5 20.0 11.4 32.7 11.4 2.1 0.3 0.0 6.2 0.4 0.0 0.3 5.2 0.5 3.1 0.6 0.0 10.3 0.6 1.1 0.0 51.8 1.0 0.4 0.0 1.9 1.0 1.9 0.1 1.9 0.0 0.4 0.0 17.5 4.0 0.1 1.5 0.0 2.0 0.3 1.1 151.0 0.3 0.4 EMILIN1 "DKFZp586M121, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 64.5;Fibroblasts: 111.3;Hepatic stellate cells: 45.0;Leydig cells: 85.1;Peritubular cells: 167.3;Sertoli cells: 72.3;Smooth muscle cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.2;BJ hTERT+: 65.0;HHSteC: 99.0;HSkMC: 109.6;SH-SY5Y: 129.4;U-138 MG: 63.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" NA NA 4300000 "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA002822: AB_1078738" "unprognostic (3.14e-1)" "unprognostic (2.44e-2)" "unprognostic (3.92e-2)" "unprognostic (3.42e-2)" "unprognostic (3.26e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (4.10e-3)" "unprognostic (3.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.97e-2)" "prognostic unfavorable (8.13e-9)" "unprognostic (8.96e-3)" "unprognostic (3.77e-2)" "unprognostic (1.20e-2)" "unprognostic (5.70e-3)" 55.5 55.7 6.9 47.0 7.1 1.9 43.6 6.4 7.1 139.8 4.6 223.5 24.9 206.3 7.4 23.3 129.2 35.4 68.9 5.9 7.5 55.5 42.4 100.7 11.7 13.0 7.6 172.4 21.2 1.4 26.9 16.2 9.5 96.4 7.9 0.3 17.5 52.1 10.3 19.1 72.0 50.3 8.3 118.1 87.6 16.9 10.4 2.4 29.7 2.6 2.2 142.9 70.2 8.6 0.9 0.7 5.9 0.9 35.8 49.0 1.1 98.2 65.0 20.7 29.7 0.5 0.8 0.6 0.9 56.6 0.1 0.9 0.2 0.2 3.8 3.1 1.3 1.8 0.5 43.9 99.0 1.5 27.0 109.6 0.1 14.2 0.0 0.2 0.2 1.3 1.0 0.9 4.3 1.1 0.9 28.8 3.2 0.5 0.7 15.6 1.3 1.2 0.0 0.4 1.6 129.4 0.3 0.5 1.1 0.4 0.4 2.5 11.9 63.6 2.0 7.6 0.4 1.7 1.8 1.1 0.7 1.3 17.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 6.9 7.1 6.4 7.1 5.9 7.5 13.0 7.6 9.5 8.3 10.4 8.6 5.2 0.0 0.5 6.5 0.4 3.3 0.2 0.0 0.0 0.6 0.8 7.1 2.9 1.5 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.4 0.6 1.9 64.5 6.3 0.0 4.0 0.2 0.4 1.5 111.3 0.5 1.3 4.5 0.2 45.0 1.0 6.4 0.0 0.3 0.3 0.0 2.5 5.8 10.0 85.1 4.1 10.6 8.4 0.5 3.6 0.0 0.5 0.3 0.8 0.1 167.3 0.8 0.2 0.5 1.0 0.0 1.1 72.3 35.3 52.4 0.6 0.4 0.4 3.1 2.9 1.3 10.7 0.1 0.1 EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 76.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 98.0;Hofbauer cells: 61.1;Kupffer cells: 52.9;Langerhans cells: 99.7;Macrophages: 97.5;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.2;BEWO: 37.8;HL-60: 37.8;HMC-1: 60.6;HSkMC: 26.1;SuSa: 25.7;THP-1: 36.7;U-2197: 46.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 25.7" HPA064576 Supported "Secreted to extracellular matrix" NA NA 840000 "Cluster 41: Basophils - Cellular respiration" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA064576: AB_2732717" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (7.91e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-3)" "unprognostic (9.91e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (3.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.96e-1)" 13.0 1.3 1.2 17.2 2.2 11.3 5.1 4.8 1.7 5.3 2.2 2.8 1.6 6.4 0.8 2.4 4.7 5.9 6.8 0.7 1.2 1.1 1.5 11.9 2.4 8.1 4.4 5.9 1.4 76.0 0.4 21.9 5.8 1.0 3.3 0.1 2.3 1.2 0.8 2.7 2.2 8.4 6.6 3.9 1.6 1.8 7.4 2.9 1.6 2.4 2.0 8.0 4.0 10.6 0.2 0.4 2.9 0.0 48.2 19.9 37.8 7.9 0.0 1.4 2.4 5.6 0.1 0.0 0.6 19.3 0.5 0.1 1.0 0.0 2.6 0.0 2.6 0.5 0.2 0.4 1.6 37.8 60.6 26.1 0.0 1.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.1 10.4 4.9 0.4 0.1 0.1 2.5 0.0 0.1 0.2 0.4 0.2 0.2 0.3 1.4 25.7 0.0 36.7 0.4 0.0 5.2 46.7 0.4 0.0 0.0 0.0 3.1 9.1 1.0 5.5 1.1 0.3 0.4 0.8 0.3 0.2 0.4 0.3 1.1 0.3 0.2 0.4 1.1 1.5 0.7 0.7 0.3 0.4 1.2 2.2 4.8 1.7 0.7 1.2 8.1 4.4 5.8 6.6 7.4 10.6 6.8 3.2 6.7 0.0 13.7 5.7 3.3 0.5 0.6 0.1 2.8 3.0 15.7 1.5 5.3 3.7 0.0 4.7 14.5 2.8 1.9 2.7 2.3 19.3 98.0 8.8 3.0 6.7 0.5 1.1 11.9 31.4 5.6 46.0 46.3 5.7 2.9 0.5 61.1 0.0 1.2 4.9 0.0 52.9 99.7 2.3 15.2 97.5 5.4 2.8 51.0 0.0 7.2 11.1 9.1 2.4 7.9 1.2 2.7 3.5 1.5 1.7 4.0 0.2 0.0 2.3 8.7 4.9 5.5 0.4 4.0 2.9 9.6 14.7 5.1 2.8 EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 53.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 17.7;Granulosa cells: 7.6;Microglial cells: 4.7;Oligodendrocyte precursor cells: 3.5;Peritubular cells: 4.9;Skeletal myocytes: 3.2" "Group enriched" "Detected in many" 5 "glioma: 10.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;HAP1: 11.1;NTERA-2: 7.0;SCLC-21H: 13.0" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in single" 4 "spinal cord: 4.1" "HPA044034, HPA059912, HPA078559" Enhanced Approved "Golgi apparatus,Microtubules,Cytokinetic bridge" "Secreted to extracellular matrix" Yes NA 1200000 "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" "Microtubules, Cytokinetic bridge" "HPA044034: AB_2678783, HPA059912: AB_2684158, HPA078559: " "unprognostic (1.66e-4)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (7.66e-2)" "unprognostic (2.18e-3)" "unprognostic (2.57e-1)" "unprognostic (6.54e-2)" "unprognostic (7.66e-2)" "unprognostic (3.13e-7)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (9.62e-2)" 0.6 1.4 2.5 0.1 2.4 0.0 3.5 2.3 3.8 8.6 1.8 4.9 0.6 2.3 53.6 0.8 4.2 0.3 7.8 2.1 2.2 1.0 0.6 0.3 0.1 3.7 2.7 8.9 0.2 0.1 1.8 0.0 3.0 6.7 0.3 0.0 1.0 9.9 0.9 3.9 1.7 0.9 2.5 0.1 2.0 1.7 2.6 0.5 0.3 2.6 0.2 2.3 4.7 3.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 11.1 0.0 0.2 0.0 1.3 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 1.3 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.4 2.3 3.8 2.1 2.2 3.7 2.7 3.0 2.5 2.6 3.0 0.6 0.0 0.0 0.7 0.0 0.9 0.2 0.0 0.0 0.3 1.2 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 17.7 0.4 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.7 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 1.8 0.1 0.0 4.7 0.0 0.1 0.0 3.5 0.1 0.0 1.2 4.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 3.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 ENAM AIH2 ENSG00000132464 Enamelin Q9NRM1 4 70628744-70646824 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.5;heart muscle: 6.5;kidney: 9.0;skeletal muscle: 4.9" "Group enriched" "Detected in some" 4 "Melanocytes: 33.8;Plasma cells: 13.4" "Group enriched" "Detected in some" 5 "pancreatic cancer: 0.6;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA 23000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.52e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.02e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (7.94e-3)" "unprognostic (4.73e-2)" "unprognostic (2.06e-1)" "unprognostic (9.06e-4)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.81e-14)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (2.12e-1)" "unprognostic (1.45e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 7.5 0.0 0.3 2.4 6.5 0.0 0.0 9.0 0.5 0.3 0.0 0.0 0.0 0.0 3.6 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 0.0 0.2 0.2 0.0 0.1 1.7 0.6 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.1 2.8 0.0 3.7 0.0 0.0 0.0 0.0 3.9 1.0 4.4 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.6 0.3 0.1 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 13.4 0.0 0.0 4.1 0.0 0.2 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.1 0.0 ENDOD1 KIAA0830 ENSG00000149218 "Endonuclease domain containing 1" O94919 11 95089846-95132645 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.5;Granulosa cells: 93.4;Oligodendrocytes: 122.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 194.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008932, HPA010517" Enhanced Approved "Nuclear membrane" "Secreted - unknown location" NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane" "HPA008932: AB_2262252, HPA010517: AB_1852351" "unprognostic (8.81e-3)" "unprognostic (1.92e-2)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (6.34e-2)" "unprognostic (2.78e-2)" "unprognostic (4.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.65e-1)" "prognostic unfavorable (8.86e-4)" "unprognostic (2.84e-1)" "prognostic favorable (6.64e-7)" "unprognostic (5.92e-2)" "unprognostic (2.35e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (3.27e-4)" 21.9 17.3 32.6 10.7 56.4 5.8 16.7 48.0 38.5 22.2 12.8 34.7 10.8 17.6 15.1 24.7 18.5 15.8 13.1 30.3 43.2 24.3 5.9 13.9 10.2 48.2 49.9 14.6 5.7 36.3 14.9 15.9 55.8 47.5 38.6 3.4 17.1 28.3 52.3 30.1 19.4 20.8 43.4 32.5 10.3 10.3 47.4 4.0 16.2 34.7 8.8 13.6 23.4 77.9 3.7 5.8 7.0 4.3 194.4 61.9 29.3 27.2 6.0 7.2 7.4 28.3 48.8 26.4 32.7 21.7 16.0 36.0 6.9 37.3 2.8 21.3 5.2 57.4 2.6 12.1 21.3 10.7 71.0 56.3 47.6 4.1 13.3 48.5 24.9 24.8 11.8 16.7 26.8 9.9 4.5 0.4 1.6 41.2 18.2 19.5 0.0 11.1 21.0 30.6 3.7 2.9 11.5 11.4 21.2 9.6 11.6 2.9 17.9 38.6 11.3 26.1 11.7 13.8 11.0 2.2 11.7 5.6 87.8 1.2 0.8 0.6 3.6 2.2 3.4 4.6 2.3 3.1 1.9 4.7 1.9 2.3 0.4 2.2 3.9 0.8 1.5 4.2 32.6 56.4 48.0 38.5 30.3 43.2 48.2 49.9 55.8 43.4 47.4 77.9 34.1 9.6 19.4 22.9 15.6 8.0 18.9 14.9 7.4 2.4 8.4 15.9 10.9 20.0 16.2 11.0 0.0 3.6 9.9 99.5 1.9 5.5 2.7 7.1 13.8 32.4 16.2 29.9 24.9 8.9 7.8 16.9 10.2 22.9 14.5 93.4 43.2 3.9 3.1 0.0 30.2 22.2 8.2 3.4 4.9 4.4 10.2 15.6 28.4 16.9 4.3 2.2 23.7 19.1 122.9 7.9 44.5 15.1 3.3 17.7 26.9 9.2 5.8 0.8 39.5 15.9 34.5 0.4 2.5 27.8 12.5 12.4 8.8 18.5 21.0 8.8 ENDOU "P11, PP11, PRSS26" ENSG00000111405 "Endonuclease, poly(U) specific" P21128 12 47709734-47725567 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.9;vagina: 31.0" "Cell type enhanced" "Detected in some" "Adipocytes: 6.9;Glandular and luminal cells: 9.6;Squamous epithelial cells: 5.2;Suprabasal keratinocytes: 9.1;Syncytiotrophoblasts: 34.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.2;SK-BR-3: 4.9;SuSa: 4.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012388, HPA067448" Enhanced "Secreted in other tissues" NA NA 14000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA012388: AB_1854860, HPA067448: AB_2685843" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "prognostic favorable (6.29e-4)" "unprognostic (6.50e-2)" "unprognostic (5.49e-2)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" 1.8 0.1 2.5 0.1 2.8 0.2 1.7 2.6 3.1 19.5 1.8 0.7 0.1 0.5 1.0 82.9 0.9 0.5 0.6 2.8 2.1 1.1 0.1 0.7 0.3 2.5 2.6 1.8 0.2 0.0 0.5 2.5 2.7 0.4 0.1 0.1 23.2 0.2 0.5 21.1 0.4 0.5 2.2 0.3 0.6 0.3 2.7 0.1 0.9 0.1 8.8 0.7 31.0 2.3 0.0 0.0 0.0 0.0 0.3 1.1 0.7 0.2 0.9 0.8 0.7 0.1 0.0 2.2 0.5 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.9 0.0 4.6 0.1 0.0 0.1 0.2 0.0 0.6 0.1 1.2 1.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.8 2.6 3.1 2.8 2.1 2.5 2.6 2.7 2.2 2.7 2.3 6.9 0.0 0.0 2.0 0.1 1.7 0.2 0.0 0.0 0.2 0.4 0.4 1.2 0.0 0.7 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.1 2.4 0.8 3.5 0.0 0.0 0.1 0.0 1.0 0.8 0.0 9.6 0.0 0.0 2.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.1 1.5 0.1 3.6 1.0 0.1 0.1 0.0 0.5 0.5 0.1 0.0 1.2 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.2 0.0 0.0 5.2 9.1 34.3 0.0 0.2 0.0 0.1 ENHO "C9orf165, UNQ470" ENSG00000168913 "Energy homeostasis associated" Q6UWT2 9 34521043-34522990 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 16 "brain: 475.8;choroid plexus: 256.0" "Cell type enhanced" "Detected in many" "Astrocytes: 71.2;Muller glia cells: 145.1;Oligodendrocyte precursor cells: 28.6" "Cancer enhanced" "Detected in many" "glioma: 44.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "myeloid DC: 28.1" "Lineage enriched" "Detected in many" 8 "dendritic cells: 28.1" "Cell line enhanced" "Detected in many" "AN3-CA: 16.7;NTERA-2: 22.9;SCLC-21H: 11.6;SH-SY5Y: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042575 Approved "Secreted in brain" NA NA 4240000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "HPA042575: AB_10794914" "unprognostic (2.63e-2)" "unprognostic (9.53e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.30e-1)" "unprognostic (7.51e-2)" "unprognostic (9.93e-2)" "unprognostic (1.34e-2)" "unprognostic (5.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.78e-4)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.47e-2)" "unprognostic (1.87e-1)" "unprognostic (5.50e-2)" "unprognostic (8.76e-2)" 1.5 0.8 385.2 0.9 422.3 0.8 4.4 360.6 475.8 2.0 256.0 5.9 2.2 0.4 0.2 0.4 2.8 0.7 2.1 344.8 364.6 1.0 23.5 1.5 0.3 400.8 408.7 0.6 1.6 2.3 11.4 0.1 373.1 8.9 2.3 5.7 1.7 0.5 1.0 5.5 4.7 0.2 380.4 0.6 5.5 16.0 459.9 0.2 0.5 0.5 0.2 1.3 1.5 321.5 0.2 1.2 6.5 16.7 0.2 0.0 0.4 0.0 0.0 2.6 2.7 0.7 0.3 2.9 4.5 0.0 5.3 0.2 7.6 0.5 0.6 0.4 7.4 0.0 0.1 1.6 0.2 0.0 3.6 0.0 0.1 0.0 0.3 0.0 0.0 5.4 0.0 2.4 0.6 0.4 0.0 0.0 22.9 1.2 4.7 0.1 0.1 0.4 0.6 0.0 11.6 11.0 0.9 5.2 0.6 0.8 0.3 2.2 0.0 0.5 2.4 0.1 0.1 1.4 1.7 0.1 0.6 0.0 3.9 0.0 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 3.6 1.0 1.5 0.0 0.7 385.2 422.3 360.6 475.8 344.8 364.6 400.8 408.7 373.1 380.4 459.9 321.5 0.2 0.0 0.5 71.2 0.3 2.8 2.3 0.0 0.0 4.6 12.0 11.7 0.7 1.5 0.1 0.0 2.1 0.2 0.3 0.0 0.0 0.8 1.0 0.2 7.0 0.7 1.8 1.7 6.4 0.2 0.4 15.5 1.1 0.1 0.0 2.3 1.1 4.8 2.9 5.0 13.6 0.0 0.0 1.0 9.3 5.4 0.3 8.3 1.8 3.7 7.8 145.1 0.0 28.6 7.2 0.0 15.0 0.4 0.0 8.4 0.3 0.5 0.0 4.1 0.0 0.4 0.8 0.7 14.9 0.1 3.1 0.0 0.7 0.1 0.4 0.7 ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 80.2;Fibroblasts: 56.9;Hepatocytes: 111.6;Peritubular cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 34.1;LHCN-M2: 21.1;U-138 MG: 27.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" NA NA 4400000 "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032904: AB_2099635, HPA062066: AB_2684674" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (7.22e-3)" "unprognostic (8.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-1)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-3)" 8.4 3.1 0.4 1.4 0.5 0.1 7.1 0.7 0.4 7.1 0.4 2.3 1.8 22.1 7.4 2.3 6.9 1.2 1.6 0.4 0.7 4.2 31.9 0.8 1.4 1.2 1.4 8.3 28.5 27.8 10.9 44.0 0.9 3.4 2.0 0.5 4.2 5.8 2.7 1.7 1.3 10.2 0.8 1.9 1.7 1.6 1.0 2.2 20.1 3.2 0.8 2.7 4.9 0.8 0.0 1.3 1.2 0.1 34.1 5.3 0.0 9.2 9.4 3.5 9.5 4.1 1.1 0.0 0.8 5.9 7.2 0.0 1.3 0.2 14.8 0.3 1.8 0.0 1.1 12.0 1.0 0.0 4.2 8.8 0.4 9.6 0.4 4.1 4.3 0.7 0.0 1.8 21.1 2.6 0.0 0.0 7.9 1.6 1.3 0.0 10.2 0.3 0.2 0.4 3.4 0.0 0.2 1.3 4.2 5.7 3.9 0.0 2.9 27.6 1.0 1.9 9.1 3.4 0.0 0.0 12.6 0.0 3.5 0.6 0.0 0.1 0.1 0.0 0.5 0.1 0.1 0.1 0.7 0.2 0.0 0.0 0.3 1.6 0.1 0.1 0.0 0.0 0.4 0.5 0.7 0.4 0.4 0.7 1.2 1.4 0.9 0.8 1.0 0.8 2.6 0.0 1.7 0.3 1.5 1.5 9.9 0.0 0.6 4.5 28.7 19.9 6.4 5.7 0.1 1.8 0.0 3.0 1.2 16.7 5.9 0.3 4.8 3.9 80.2 4.1 0.0 8.0 3.5 10.6 2.1 56.9 6.1 3.2 0.0 9.4 3.3 111.6 4.6 1.7 10.5 12.7 0.0 2.9 5.9 6.7 25.1 3.9 1.8 12.2 0.2 3.6 0.0 21.6 1.6 5.2 3.9 70.0 0.4 2.3 6.7 25.2 0.1 0.5 13.1 12.6 18.8 4.1 2.2 0.1 1.3 6.2 2.6 1.9 2.5 1.7 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.1;intestine: 44.5" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 160.0;Glandular and luminal cells: 387.2" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Group enriched" "Detected in some" 18 "HEL: 4.4;Hep G2: 14.6;HMC-1: 6.2" "Low region specificity" "Detected in some" "Region enriched" "Detected in single" 4 "spinal cord: 2.6" HPA043772 Enhanced "Secreted - unknown location" NA NA 1100000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" 1.2 6.2 0.4 1.1 0.4 0.1 6.6 0.9 0.5 32.1 0.2 9.3 16.2 3.8 1.2 0.5 2.3 1.3 0.1 0.3 0.5 10.0 5.0 0.9 0.5 0.5 0.6 0.5 0.1 0.3 0.1 0.1 0.5 2.4 8.4 0.3 18.1 15.6 0.1 0.6 44.5 0.8 0.4 0.3 0.5 0.8 0.5 9.6 0.3 0.2 0.4 0.4 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.4 0.0 14.6 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.4 0.9 0.5 0.3 0.5 0.5 0.6 0.5 0.4 0.5 0.4 0.4 0.0 1.1 5.2 0.2 0.0 2.6 0.7 1.2 0.2 1.0 0.6 0.3 0.0 2.5 0.0 0.0 0.0 0.2 9.2 1.9 0.0 1.6 160.0 46.3 1.4 0.0 2.1 2.1 0.0 0.1 0.5 0.0 387.2 36.0 0.1 0.7 1.7 0.1 0.0 4.1 1.5 0.0 0.6 1.1 0.4 1.2 1.5 1.8 2.8 0.0 0.1 1.0 3.5 0.9 0.0 1.9 0.7 0.3 2.7 53.3 9.1 5.4 0.1 0.0 0.2 1.0 2.5 0.8 0.0 0.6 0.1 2.2 0.1 4.9 1.1 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 107.2;kidney: 95.2;liver: 263.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 209.3;Hepatocytes: 134.8;Intestinal goblet cells: 77.1;Proximal enterocytes: 87.0" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.3" "Cell line enhanced" "Detected in all" "RT4: 57.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" NA NA 5900000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 8.2 7.7 5.0 11.4 7.3 8.0 12.4 7.1 6.7 7.3 7.1 94.6 72.1 6.3 7.7 11.3 5.7 12.1 7.7 5.1 6.3 95.2 263.7 6.5 5.5 7.6 7.3 6.7 4.9 7.7 5.0 5.6 7.8 37.7 107.2 9.4 10.7 4.4 15.0 8.1 68.4 9.7 6.5 6.0 42.3 8.6 7.3 4.6 6.1 9.1 5.6 16.9 7.2 9.0 9.5 7.8 8.2 15.1 16.5 15.5 9.4 9.6 7.9 6.4 7.1 5.6 10.9 10.6 4.7 12.8 6.0 10.8 8.5 14.1 7.2 8.8 4.0 7.9 5.7 30.9 15.5 4.7 8.8 12.9 14.0 8.7 18.2 8.8 13.1 17.1 8.8 15.4 9.7 13.6 5.4 5.6 2.5 8.5 15.7 6.0 8.0 5.2 11.4 57.1 5.8 6.0 16.6 12.9 9.2 6.4 18.7 4.1 10.8 12.6 12.7 7.5 7.2 10.1 16.9 8.3 8.0 8.8 11.5 18.3 1.2 9.4 2.5 2.3 1.3 1.4 1.3 1.8 1.7 1.5 2.1 2.1 0.1 0.5 1.4 0.9 1.6 1.3 5.0 7.3 7.1 6.7 5.1 6.3 7.6 7.3 7.8 6.5 7.3 9.0 8.0 16.0 6.7 8.1 4.9 3.7 6.2 8.9 5.2 6.6 15.0 7.9 5.2 10.0 11.3 7.3 4.2 8.2 4.3 209.3 25.4 6.9 19.5 10.0 13.6 7.0 16.2 36.6 5.9 12.9 6.7 7.9 23.0 25.8 1.3 9.6 9.7 134.8 6.2 10.1 8.2 77.1 14.2 9.7 1.9 12.7 2.8 5.2 5.4 11.2 5.4 4.9 8.2 2.0 11.3 9.1 58.4 5.7 3.6 28.5 87.0 63.1 6.4 12.2 13.1 6.0 5.9 27.2 19.1 8.5 3.4 3.3 4.9 10.3 60.9 39.0 ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6" O75354 20 25195693-25228075 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 289.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 41000 "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA015491: AB_2669200, HPA069555: AB_2686152" "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" 24.8 55.4 54.3 22.8 64.0 15.2 27.7 39.7 65.9 22.9 26.5 61.0 60.0 21.8 18.4 25.3 23.2 26.5 75.9 56.0 49.8 40.4 38.9 25.4 16.1 29.6 32.2 36.2 49.6 23.5 60.0 25.2 45.2 55.7 44.9 15.7 71.2 17.2 38.7 19.4 63.0 18.6 25.7 19.8 47.2 36.3 48.5 29.8 28.8 21.9 13.0 24.5 21.8 38.9 78.8 122.8 32.9 64.0 41.0 50.8 70.8 63.0 45.0 54.0 48.3 65.5 60.0 47.6 91.4 60.9 104.7 100.3 40.1 96.2 35.5 29.2 36.2 38.3 18.2 150.4 60.7 52.7 57.3 47.4 53.1 67.7 51.4 39.4 43.7 46.1 51.5 78.8 40.0 75.6 49.2 32.6 20.8 63.9 96.0 27.1 102.9 108.4 67.8 46.3 52.0 26.7 17.7 105.1 289.4 29.6 75.3 43.4 48.6 61.9 63.7 51.6 75.7 50.5 43.8 21.0 44.5 34.1 116.3 0.1 25.2 4.9 18.8 17.0 25.6 8.7 16.5 15.0 26.4 11.0 16.9 15.5 1.1 14.1 7.6 18.5 17.2 22.1 54.3 64.0 39.7 65.9 56.0 49.8 29.6 32.2 45.2 25.7 48.5 38.9 6.4 19.2 28.5 12.4 9.9 9.8 16.2 23.6 6.2 19.2 25.8 21.8 5.8 25.8 14.8 18.4 10.4 63.2 11.0 81.4 9.8 42.5 22.1 10.5 7.6 7.6 34.0 4.2 18.6 40.1 21.7 12.8 52.5 15.4 3.8 65.2 14.3 15.0 26.7 25.2 19.4 57.5 26.4 17.7 17.4 65.2 20.5 17.6 10.6 11.2 16.0 4.2 10.3 13.0 9.2 33.8 59.8 42.2 16.5 27.9 68.4 13.5 10.7 9.1 6.6 6.3 9.6 3.0 8.8 8.6 6.0 59.8 12.0 25.8 72.6 12.1 EPDR1 "EPDR, MERP-1, MERP1, UCC1" ENSG00000086289 "Ependymin related 1" Q9UM22 7 37683843-37951936 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.5;Peritubular cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-937: 122.2;WM-115: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026298, HPA072321" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB026298: AB_425991, HPA072321: " "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (4.44e-3)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic unfavorable (6.97e-4)" "unprognostic (2.53e-2)" "unprognostic (2.75e-1)" "unprognostic (3.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.85e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (4.13e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.00e-4)" 23.1 40.3 46.3 4.2 41.4 4.5 11.3 38.4 82.3 38.5 27.3 10.5 13.4 41.7 13.6 8.4 28.1 10.1 27.4 45.4 67.5 16.4 10.9 27.1 4.9 81.9 50.4 34.0 9.4 8.0 9.4 4.9 83.2 34.5 8.4 14.3 13.8 41.0 122.9 3.2 13.2 29.9 50.9 17.2 5.7 13.0 58.5 11.4 31.0 72.1 3.0 8.8 17.0 38.9 0.2 77.9 6.4 0.1 57.9 20.8 0.1 5.9 0.0 3.0 9.1 7.7 5.1 0.0 84.2 86.0 88.7 0.2 1.8 0.7 0.0 0.1 9.8 34.9 10.2 49.5 0.5 29.1 0.2 35.1 0.0 21.1 0.4 20.0 0.0 34.3 0.0 25.2 51.6 5.1 11.3 25.1 24.0 0.0 11.6 35.2 22.3 30.6 47.3 19.3 8.4 29.3 0.0 3.8 28.2 15.3 0.1 20.4 0.0 16.6 27.8 46.6 36.7 33.8 15.4 0.5 75.5 122.2 114.7 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.4 0.0 0.8 0.0 2.2 0.0 0.1 46.3 41.4 38.4 82.3 45.4 67.5 81.9 50.4 83.2 50.9 58.5 38.9 6.4 32.1 46.2 12.7 1.4 1.3 7.8 3.5 1.2 5.7 1.1 10.5 20.7 7.2 12.7 1.8 0.0 0.5 6.8 5.1 17.6 10.0 0.3 5.5 31.8 2.4 3.6 25.6 36.9 8.0 0.2 15.0 1.5 5.9 2.5 95.5 7.5 10.7 3.1 11.8 39.3 5.1 0.0 1.6 2.0 2.1 28.3 3.1 28.4 14.0 14.2 13.3 2.1 24.6 13.0 19.7 6.9 98.9 0.2 14.6 19.3 14.8 5.7 7.2 6.6 46.4 23.9 0.3 1.8 0.5 0.3 0.1 1.2 28.7 6.4 2.6 EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 49.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.0;Basal prostatic cells: 7.3;Basal squamous epithelial cells: 25.6;Urothelial cells: 5.1" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTCEpi: 157.9;U-2197: 74.8" "Not detected" "Not detected" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Vesicles "HPA014420: AB_10601551" "unprognostic (7.51e-2)" "unprognostic (8.08e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.38e-4)" "unprognostic (2.20e-1)" "unprognostic (2.01e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (4.06e-4)" "unprognostic (3.84e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.40e-4)" 1.6 0.1 0.2 1.6 0.1 0.3 1.4 0.4 0.6 5.2 0.1 0.1 0.1 0.0 1.1 49.0 1.5 0.1 0.8 0.2 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.1 0.1 2.2 0.1 0.5 0.1 0.2 0.0 0.2 3.6 3.1 0.1 3.5 0.1 0.0 0.1 0.3 0.0 1.1 0.1 0.9 0.0 0.0 3.4 1.3 9.6 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.0 0.0 0.4 0.0 0.8 0.0 0.1 1.8 0.2 3.6 0.0 2.8 0.0 0.0 0.0 0.5 20.2 0.0 0.2 0.0 0.7 0.0 157.9 2.9 11.7 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.0 0.0 0.3 0.0 3.6 0.4 0.0 0.0 0.3 0.3 0.1 0.0 8.3 3.3 0.0 0.0 0.5 0.0 0.2 0.4 0.1 74.8 0.2 0.0 0.0 0.1 0.7 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.3 0.3 0.1 0.7 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.4 0.0 0.0 1.5 0.0 0.0 6.0 7.3 0.9 25.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 3.1 0.0 0.1 1.8 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 3.0 1.6 0.1 0.2 0.0 0.0 5.1 EPO EP ENSG00000130427 Erythropoietin P01588 7 100720468-100723700 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Erythrocyte maturation" Hormone "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 47.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.9;Exocrine glandular cells: 4.2;Extravillous trophoblasts: 14.0;Hepatocytes: 19.5;Pancreatic endocrine cells: 3.7;Syncytiotrophoblasts: 2.9" "Group enriched" "Detected in many" 5 "liver cancer: 2.7;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 1.6;Hep G2: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB010336 Supported "Secreted to blood" NA NA 12300 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB010336: AB_2098408" "unprognostic (2.93e-1)" "unprognostic (1.57e-2)" "unprognostic (1.08e-3)" "unprognostic (7.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.52e-2)" "unprognostic (5.16e-2)" "unprognostic (9.70e-2)" "unprognostic (2.44e-3)" "unprognostic (3.31e-1)" "prognostic unfavorable (2.18e-6)" "unprognostic (4.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (3.34e-1)" 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.3 2.9 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.1 0.4 3.1 47.2 0.1 0.0 0.2 0.1 0.2 8.3 0.0 0.0 0.0 0.2 0.5 0.0 0.2 1.4 0.5 0.0 0.4 0.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 4.2 14.0 0.0 0.0 0.0 0.0 0.1 1.4 19.5 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 2.9 0.0 0.0 0.0 0.0 EPPIN "CT71, dJ461P17.2, EPPIN1, EPPIN2, EPPIN3, SPINLW1, WAP7, WFDC7" ENSG00000101448 "Epididymal peptidase inhibitor" O95925 20 45540626-45547752 "Predicted intracellular proteins, Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 83 "epididymis: 327.9;testis: 84.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 30.0;Granulosa cells: 13.6;Late spermatids: 29.2;Respiratory ciliated cells: 32.5;Sertoli cells: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.8;U-87 MG: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA067335 Supported "Secreted in male reproductive system" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA067335: " "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (3.08e-3)" "unprognostic (1.06e-2)" "unprognostic (3.75e-2)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (2.00e-2)" 0.3 0.3 0.7 0.3 1.1 2.4 0.2 1.9 2.4 0.5 0.1 0.4 0.7 0.7 327.9 0.3 1.3 0.2 0.1 0.9 0.0 0.2 2.3 0.4 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.6 0.2 0.4 1.2 0.3 0.8 0.2 0.8 0.7 0.1 0.0 0.4 0.2 84.2 0.4 0.0 0.7 0.0 0.2 0.1 0.0 2.0 0.8 0.1 0.3 0.3 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.5 0.3 0.6 0.3 0.0 0.6 0.3 0.1 0.0 0.0 0.5 0.1 0.3 0.5 0.4 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.6 1.8 0.0 0.4 0.2 0.7 0.8 0.1 0.2 0.7 0.2 0.5 0.1 0.2 0.3 0.5 0.3 0.1 0.3 0.3 0.4 0.4 0.7 0.7 0.6 0.9 0.5 0.6 0.8 0.3 2.6 0.2 0.8 0.8 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.7 1.1 1.9 2.4 0.9 0.0 0.1 0.0 0.6 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.1 0.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 30.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 29.2 4.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 32.5 0.0 13.1 0.0 0.4 5.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 EPPIN-WFDC6 SPINLW1-WFDC6 ENSG00000249139 "EPPIN-WFDC6 readthrough" O95925 20 45534196-45547662 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 78 "epididymis: 63.6;testis: 53.6" "Cell type enriched" "Detected in single" 6 "Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA067335 Supported "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "HPA067335: " "unprognostic (1.46e-3)" "unprognostic (6.38e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 63.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EPYC "DSPG3, Pg-Lb, SLRR3B" ENSG00000083782 Epiphycan Q99645 12 90963682-91005026 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "placenta: 6.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 2.4;ovarian cancer: 7.7;pancreatic cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-RPE1: 3.0" "Region enhanced" "Detected in single" "midbrain: 1.4" "Group enriched" "Detected in some" 5 "amygdala: 1.7;basal ganglia: 2.9;cerebral cortex: 2.7;hippocampal formation: 2.2" "HPA038212, HPA045455" Approved "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA038212: AB_10672739, HPA045455: AB_2679330" "unprognostic (2.25e-1)" "unprognostic (2.08e-1)" "unprognostic (2.79e-1)" "unprognostic (4.28e-2)" "unprognostic (1.81e-2)" "unprognostic (4.07e-2)" "unprognostic (9.20e-2)" "unprognostic (3.23e-1)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.77e-2)" "unprognostic (6.44e-9)" "unprognostic (2.83e-2)" "unprognostic (3.08e-1)" "unprognostic (8.68e-2)" "unprognostic (1.20e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 EQTN "AFAF, C9orf11, equatorin, SPACA8" ENSG00000120160 Equatorin Q9NQ60 9 27284654-27297150 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 37.8" "Cell type enriched" "Detected in some" 10 "Early spermatids: 739.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015089, HPA015504" Enhanced Approved "Plasma membrane,Actin filaments" "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane, Actin filaments" "HPA015089: AB_1845795, HPA015504: AB_2067598" "unprognostic (7.83e-2)" "unprognostic (1.55e-1)" "unprognostic (5.64e-2)" "unprognostic (8.12e-3)" "unprognostic (1.34e-3)" "unprognostic (4.41e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.32e-1)" "unprognostic (1.89e-1)" "unprognostic (5.67e-2)" "unprognostic (1.14e-1)" "unprognostic (4.59e-2)" "unprognostic (8.46e-2)" "unprognostic (3.90e-2)" "unprognostic (1.42e-1)" 0.2 0.0 0.4 0.0 1.2 0.0 0.2 0.8 0.6 0.2 0.2 0.3 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.2 0.0 0.3 0.2 1.5 0.9 0.5 0.4 0.0 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.1 0.1 0.2 0.3 0.0 0.8 0.2 0.2 37.8 1.6 0.0 0.2 0.1 0.0 0.1 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.8 0.6 0.2 0.4 1.5 0.9 1.3 0.8 1.6 2.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 739.3 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 67.8 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.7 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.2 16.2 2.4 0.0 0.3 0.1 0.0 0.1 0.2 0.1 ERAP1 "A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP" ENSG00000164307 "Endoplasmic reticulum aminopeptidase 1" Q9NZ08 5 96760810-96808100 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 72.8;Inhibitory neurons: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025095, HPA042317" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 30000000 "Cluster 34: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB025095: , HPA042317: AB_2677946" "unprognostic (2.33e-3)" "unprognostic (3.45e-1)" "unprognostic (1.84e-3)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.38e-1)" "unprognostic (1.88e-3)" "unprognostic (5.37e-2)" "unprognostic (1.45e-1)" "unprognostic (7.94e-2)" "unprognostic (4.52e-2)" "unprognostic (3.23e-1)" "unprognostic (7.09e-2)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (5.14e-2)" 51.5 15.8 3.7 37.0 4.3 27.9 25.5 3.1 5.6 21.8 2.3 37.9 63.4 22.0 14.4 13.2 25.5 23.7 17.1 3.4 5.2 16.4 32.9 31.2 38.2 8.4 5.7 20.7 13.7 19.1 8.2 47.0 7.0 18.6 43.7 12.4 19.3 22.0 20.9 36.5 55.1 21.7 5.0 30.8 33.7 9.1 6.6 63.7 17.5 19.6 36.8 27.3 11.7 6.8 25.9 14.1 21.3 20.0 114.7 111.5 61.4 18.3 59.6 44.0 76.2 17.6 91.1 75.3 37.6 36.0 61.8 25.7 17.8 38.1 27.3 139.8 7.5 24.7 10.0 13.9 130.9 12.0 44.1 46.8 16.2 50.6 15.5 64.3 61.1 48.8 12.9 74.7 26.7 11.6 113.2 12.4 10.6 3.1 10.4 82.4 28.8 38.4 32.8 39.0 7.8 5.5 29.6 19.8 28.6 14.6 17.1 57.0 48.8 37.4 12.6 6.2 31.1 26.9 53.9 57.8 40.2 40.2 22.5 28.8 15.2 18.0 22.6 12.3 20.2 14.8 19.2 19.1 10.5 18.3 22.3 18.1 15.8 23.1 20.6 16.7 13.9 13.7 3.7 4.3 3.1 5.6 3.4 5.2 8.4 5.7 7.0 5.0 6.6 6.8 11.1 9.6 16.3 34.0 15.3 25.0 14.2 19.2 8.6 13.6 6.6 3.9 10.6 10.0 16.9 9.2 2.1 9.6 21.1 24.4 0.0 12.4 27.0 12.7 15.0 16.3 10.3 14.1 72.8 15.5 11.9 18.4 16.3 19.8 15.2 13.9 16.8 28.0 17.6 3.3 79.3 23.9 4.1 29.9 16.1 7.3 9.9 22.9 7.2 24.4 32.5 9.0 20.6 32.6 70.1 12.3 14.1 16.1 32.3 13.5 47.3 6.9 23.1 7.6 0.0 10.3 22.6 1.4 1.8 9.8 11.1 9.2 21.8 5.7 27.3 14.9 ERAP2 "L-RAP, LRAP" ENSG00000164308 "Endoplasmic reticulum aminopeptidase 2" Q6P179 5 96875986-96919703 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 176.1;GAMG: 105.0;hTEC/SVTERT24-B: 83.2;MOLT-4: 98.8;TIME: 188.7" "Low region specificity" "Detected in all" "CAB025618, HPA034498, HPA064360" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 11000000 "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB025618: , HPA034498: AB_2674191, HPA064360: " "unprognostic (4.62e-2)" "unprognostic (1.60e-1)" "unprognostic (4.98e-2)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (8.71e-2)" "unprognostic (2.60e-2)" "unprognostic (1.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.01e-1)" "unprognostic (9.54e-3)" "unprognostic (6.59e-2)" "unprognostic (8.48e-2)" "unprognostic (4.65e-2)" "unprognostic (3.05e-1)" 7.8 7.1 3.0 31.5 3.0 7.5 11.9 2.3 4.3 12.2 3.0 16.2 32.6 8.4 17.5 10.5 7.0 11.0 7.5 2.9 2.5 11.3 14.5 18.1 46.4 4.3 3.3 8.5 2.9 3.7 3.6 11.0 3.5 10.3 6.2 2.3 6.6 7.0 8.9 10.1 21.5 3.4 2.7 36.7 19.0 1.7 3.8 49.9 5.6 9.9 29.7 14.7 6.8 3.5 2.1 2.4 1.7 0.9 1.9 3.8 0.6 8.1 13.8 7.3 12.3 7.9 176.1 12.2 35.1 11.5 105.0 2.9 0.9 65.4 5.8 4.3 7.9 0.6 3.0 8.5 2.7 43.2 19.2 25.3 12.8 83.2 0.6 1.2 4.9 27.4 0.2 25.8 20.8 1.4 98.8 22.5 0.2 0.0 3.7 45.7 16.2 29.3 55.2 15.4 3.5 0.2 1.1 0.9 16.5 0.4 6.5 1.7 188.7 3.9 1.1 10.0 24.6 26.2 23.2 4.2 50.8 5.8 0.9 23.0 12.1 15.4 24.8 27.5 31.3 28.5 34.6 30.6 19.8 17.7 37.4 28.9 4.2 45.4 28.5 6.9 34.6 27.6 3.0 3.0 2.3 4.3 2.9 2.5 4.3 3.3 3.5 2.7 3.8 3.5 46.7 32.1 20.0 11.8 62.6 5.7 11.2 24.4 12.0 1.5 3.1 5.8 4.4 8.6 15.9 44.1 0.0 11.5 35.6 48.1 0.0 5.3 0.3 7.0 10.6 34.1 1.8 15.8 2.5 25.5 17.0 23.4 17.3 7.4 7.0 33.4 31.4 16.3 12.3 0.0 2.1 23.3 8.2 29.4 14.2 0.7 10.5 33.0 7.2 21.5 19.4 6.5 20.6 7.1 4.9 22.1 27.6 7.9 56.0 4.3 52.4 6.2 15.7 2.8 0.0 12.2 12.2 0.9 0.8 10.0 3.0 6.7 54.2 9.3 34.2 10.5 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 129.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 179.1;Kupffer cells: 133.9;Langerhans cells: 171.1;Macrophages: 570.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 270.0;CAPAN-2: 76.7;hTEC/SVTERT24-B: 83.7;U-2197: 181.4;U-87 MG: 307.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054373 Approved Vesicles "Secreted to blood" NA NA 46000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" 4.5 0.0 0.3 10.3 0.3 129.0 2.5 0.2 0.5 1.9 0.2 2.0 0.2 0.2 0.2 12.6 0.8 5.7 0.7 0.3 0.1 0.1 0.2 2.7 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.6 0.4 0.1 3.4 0.1 1.3 0.0 0.2 9.3 1.6 3.0 0.0 0.5 0.2 0.1 0.6 0.1 0.1 0.0 1.0 4.9 4.0 0.3 1.4 41.1 0.0 0.0 3.8 6.6 0.1 9.2 270.0 2.6 1.6 32.5 76.7 0.0 44.1 0.0 20.1 2.4 0.0 59.3 2.7 0.0 0.0 1.2 1.6 1.2 1.1 0.1 0.1 3.9 20.2 83.7 43.5 0.0 0.0 0.0 0.1 0.5 0.2 0.4 0.1 0.1 0.1 0.2 0.6 0.1 0.0 0.1 0.6 1.6 0.0 0.0 27.0 0.2 0.0 0.0 0.1 0.0 0.0 1.6 0.6 181.4 0.0 0.0 0.0 0.2 307.0 0.0 0.2 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.3 0.1 0.2 0.1 0.4 0.0 0.6 0.3 4.9 6.4 7.2 0.0 5.7 5.4 5.6 179.1 4.0 0.0 24.4 2.3 18.2 5.7 82.4 0.0 0.0 0.4 2.2 56.3 0.0 1.8 3.7 2.4 0.7 2.5 3.6 17.0 0.1 0.2 0.7 4.4 0.5 3.9 7.0 0.1 0.4 1.9 26.8 0.0 1.8 38.2 16.2 133.9 171.1 1.0 0.3 570.7 7.2 0.0 23.2 0.0 0.0 0.0 0.0 0.8 27.1 0.0 11.7 2.5 32.4 0.2 41.9 0.0 0.0 2.5 3.1 0.5 0.3 3.8 9.2 0.7 3.3 0.2 33.1 7.4 ERFE "C1QTNF15, CTRP15, FAM132B, FLJ37034" ENSG00000178752 Erythroferrone Q4G0M1 2 238158970-238168900 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 11.8;skeletal muscle: 14.9;testis: 12.8;thyroid gland: 24.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 6.3;Club cells: 2.5;Collecting duct cells: 1.8;Distal tubular cells: 3.9;Glandular and luminal cells: 1.8;granulocytes: 5.1;Respiratory ciliated cells: 2.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 20.3;RH-30: 25.6" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 277000 "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (1.66e-1)" "unprognostic (9.14e-2)" "unprognostic (3.64e-4)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.84e-1)" "unprognostic (9.61e-4)" "unprognostic (4.68e-3)" "unprognostic (3.16e-3)" "unprognostic (9.63e-2)" "unprognostic (9.11e-2)" "unprognostic (1.31e-4)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (4.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.33e-2)" 0.7 0.1 3.3 2.2 4.0 4.1 0.4 4.6 6.7 0.7 2.2 0.5 0.6 0.4 0.0 0.4 0.5 0.3 0.9 3.9 2.4 11.8 0.5 0.9 0.1 2.4 2.5 0.1 0.4 0.0 0.1 1.2 2.5 0.7 0.2 0.0 0.3 0.4 14.9 0.1 0.9 0.4 2.2 0.8 0.5 12.8 2.7 0.1 24.9 0.6 0.1 2.3 0.3 2.7 3.1 0.8 1.4 3.0 0.2 4.9 0.3 2.0 3.2 4.9 8.7 0.2 7.7 0.0 5.4 0.5 10.0 0.3 13.7 0.7 4.5 0.0 15.2 0.0 0.3 0.2 1.8 0.1 1.1 10.5 1.5 20.3 14.3 0.6 0.1 6.5 4.6 0.0 13.6 3.8 0.0 8.9 2.1 0.9 1.5 17.3 25.6 0.8 10.7 0.1 0.4 7.7 3.1 0.5 9.7 2.5 0.4 15.5 1.0 8.2 7.1 3.2 10.7 0.0 0.0 1.1 12.2 4.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.0 4.6 6.7 3.9 2.4 2.4 2.5 2.5 2.2 2.7 2.7 0.2 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.5 1.8 0.0 0.2 0.7 0.0 3.9 0.1 0.0 1.2 0.2 0.5 0.0 0.0 0.0 0.0 0.2 1.2 0.0 1.8 5.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 ERVH48-1 "C21orf105, NDUFV3-AS1, SUPYN" ENSG00000233056 "Endogenous retrovirus group 48 member 1" M5A8F1 21 42916803-42925646 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "placenta: 152.2" "Group enriched" "Detected in some" 8 "Cytotrophoblasts: 130.7;Extravillous trophoblasts: 258.3;Syncytiotrophoblasts: 88.8" "Cancer enriched" "Detected in some" 18 "testis cancer: 74.5" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 7 "BEWO: 296.4" "Secreted in female reproductive system" NA NA 57000 "Cluster 1: Neutrophils - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (5.28e-2)" "unprognostic (5.92e-2)" "unprognostic (5.66e-2)" "unprognostic (9.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.92e-2)" "unprognostic (3.48e-1)" "unprognostic (1.52e-2)" "unprognostic (7.74e-2)" "unprognostic (3.12e-3)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" 0.1 0.4 0.5 0.2 0.8 0.7 0.1 2.3 1.3 0.0 0.7 0.1 0.3 0.2 0.2 0.1 0.1 0.3 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.6 0.0 0.2 0.7 0.0 152.2 0.7 0.7 0.0 1.5 0.4 0.0 0.4 0.8 0.5 0.0 0.0 0.4 0.3 1.4 0.4 1.3 0.4 0.0 0.0 0.0 0.5 0.0 0.3 0.7 0.1 0.0 0.0 296.4 0.1 0.0 0.0 0.0 11.9 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 2.8 1.4 0.4 0.1 1.2 0.2 0.0 0.0 0.2 0.0 0.1 11.1 1.0 0.7 0.6 0.0 0.2 8.2 5.0 0.9 0.0 0.3 6.4 0.3 0.1 0.0 0.2 0.4 0.3 0.1 0.0 0.0 44.6 0.3 0.2 0.3 0.2 0.6 0.4 0.1 0.9 2.9 0.5 0.4 3.0 0.2 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.6 7.7 0.0 0.0 0.0 0.0 0.0 0.5 0.8 2.3 1.3 0.6 0.0 0.6 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 130.7 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.4 0.0 0.0 0.0 0.0 258.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 19.2 3.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.0 88.8 0.0 0.0 0.0 0.0 ERVMER34-1 envMER34 ENSG00000226887 "Endogenous retrovirus group MER34 member 1, envelope" Q9H9K5 4 52722618-52751586 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 12.9;placenta: 10.8" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 74.4;Extravillous trophoblasts: 102.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 46.9;hTCEpi: 32.5;RPTEC TERT1: 24.2" "HPA011423, HPA024053" Approved Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 6000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA011423: AB_2668510, HPA024053: " "unprognostic (5.34e-2)" "unprognostic (1.29e-1)" "unprognostic (1.91e-3)" "unprognostic (5.86e-2)" "unprognostic (4.08e-4)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.88e-4)" "unprognostic (5.28e-2)" "unprognostic (2.99e-2)" "unprognostic (2.39e-3)" "unprognostic (2.62e-3)" "unprognostic (4.23e-2)" "unprognostic (1.03e-2)" "unprognostic (1.32e-2)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" "unprognostic (1.82e-1)" 0.1 0.5 1.0 0.2 0.7 0.0 0.9 0.7 1.2 0.8 0.7 0.2 0.2 0.6 0.6 1.2 0.5 0.2 2.6 0.8 0.8 3.5 0.1 0.6 0.2 0.9 0.7 1.3 0.5 12.9 0.0 10.8 1.0 0.4 0.4 0.0 0.4 0.8 0.0 0.3 0.1 0.2 0.9 0.5 0.4 0.7 0.8 0.0 0.4 0.0 0.4 0.5 0.6 1.0 7.6 0.3 1.5 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 46.9 9.9 0.0 1.0 0.1 0.7 0.5 0.0 3.4 0.0 0.0 0.4 0.0 0.1 0.5 0.6 0.0 0.0 2.1 32.5 0.0 4.8 0.0 0.0 0.0 2.7 0.0 0.1 0.5 0.0 0.0 3.1 3.0 1.4 0.0 0.0 0.0 24.2 0.7 2.0 0.4 3.1 1.3 0.0 4.7 4.1 0.7 0.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.7 1.2 0.8 0.8 0.9 0.7 1.0 0.9 0.8 1.0 0.1 0.0 0.0 0.0 0.5 0.5 1.8 2.3 2.2 0.0 2.2 1.9 2.9 0.0 0.6 7.3 0.0 74.4 0.0 0.1 0.0 2.5 4.2 0.6 0.9 1.3 0.0 0.0 0.4 0.8 102.9 1.5 0.0 1.7 0.0 2.6 0.0 0.0 7.4 0.0 0.2 0.3 2.0 0.0 0.0 3.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.0 0.0 3.7 0.0 3.0 0.1 0.0 0.0 0.2 0.5 0.2 0.4 2.8 0.1 17.4 0.0 0.2 0.4 1.4 ESM1 ENSG00000164283 "Endothelial cell specific molecule 1" Q9NQ30 5 54977867-55022671 "Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 19.9;thyroid gland: 17.3" "Cell type enriched" "Detected in some" 8 "Endothelial cells: 142.4" "Cancer enriched" "Detected in all" 8 "renal cancer: 65.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 302.2;TIME: 568.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB047364 Approved "Secreted to blood" NA NA 1540000 340000 "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB047364: " "unprognostic (4.70e-2)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.63e-3)" "unprognostic (2.31e-3)" "unprognostic (4.68e-2)" "unprognostic (1.55e-1)" "unprognostic (6.85e-3)" "unprognostic (1.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (4.00e-4)" "unprognostic (7.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-2)" "unprognostic (2.94e-1)" 1.3 4.2 0.4 0.7 0.7 0.6 0.5 0.2 1.1 2.0 0.8 0.2 0.7 3.6 0.4 0.2 0.2 1.3 3.6 0.3 1.3 19.9 2.6 11.3 1.2 0.5 0.5 0.7 2.3 6.0 2.2 0.4 0.3 3.5 0.0 0.1 6.3 3.7 0.2 0.1 0.8 0.7 0.8 0.9 0.3 0.6 1.6 0.2 17.3 0.2 0.6 1.3 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 79.8 9.5 4.1 1.0 0.0 0.0 0.1 7.4 5.7 2.3 0.0 0.0 1.0 14.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.7 0.4 8.5 302.2 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 568.0 4.7 13.7 39.2 21.3 0.1 0.0 0.0 1.7 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.1 0.4 0.7 0.2 1.1 0.3 1.3 0.5 0.5 0.3 0.8 1.6 0.4 6.3 0.0 0.6 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 16.1 0.0 0.1 0.1 142.4 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.0 0.7 0.0 2.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.5 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 1.5 1.7 0.1 0.3 0.0 0.1 0.1 0.6 1.1 0.0 0.7 EYS "bA166P24.2, bA307F22.3, bA74E24.1, C6orf178, C6orf179, C6orf180, dJ1018A4.2, dJ303F19.1, EGFL10, EGFL11, RP25, SPAM" ENSG00000188107 "Eyes shut homolog" Q5T1H1 6 63719980-65707226 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "retina: 24.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 316.9;Early spermatids: 87.3;Inhibitory neurons: 83.8;Late spermatids: 45.7;Rod photoreceptor cells: 140.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "Karpas-707: 1.5;SCLC-21H: 1.1" "Secreted in other tissues" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (2.92e-2)" "unprognostic (1.90e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-2)" "unprognostic (2.16e-3)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (6.38e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (2.04e-1)" "unprognostic (2.18e-1)" "unprognostic (2.61e-4)" "unprognostic (1.89e-1)" "unprognostic (8.41e-2)" "unprognostic (6.38e-3)" "unprognostic (1.11e-1)" 0.6 0.0 0.3 0.0 0.4 0.3 0.2 0.6 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.5 0.1 0.6 24.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.3 0.3 0.4 0.6 0.6 0.4 0.0 0.4 0.1 0.5 0.0 0.1 0.3 0.1 0.0 1.8 3.9 0.5 0.3 0.7 0.1 0.6 8.3 0.1 0.0 2.1 0.0 0.7 1.8 316.9 0.8 0.2 0.0 0.0 0.4 87.3 1.0 1.0 0.7 20.3 0.0 22.0 0.4 0.4 0.7 0.0 2.1 2.5 0.0 0.0 0.3 0.1 10.1 83.8 0.4 0.0 0.0 0.6 45.7 0.9 0.2 0.0 3.7 0.1 4.0 0.0 5.5 12.9 0.3 0.0 0.7 0.1 0.2 0.1 0.3 0.1 140.2 0.0 1.5 0.3 2.6 1.3 0.4 0.1 1.1 0.6 0.3 0.2 0.2 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 27.6;Hepatocytes: 75.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.2 17.1 0.2 0.1 0.0 0.0 13.1 0.0 0.2 0.0 27.6 243.2 8.4 0.0 0.0 0.3 0.3 58.9 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.7 0.0 8.7 0.0 0.0 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 27.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 2.5 1.8 0.0 0.0 0.2 0.3 11.7 2.3 0.0 0.0 0.0 0.1 0.0 5.3 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.7 0.0 0.0 0.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 1.1 5.5 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402141-177409564 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 226 "liver: 604.6" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 523.0" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "classical monocyte: 1.2;eosinophil: 3.6" "Group enriched" "Detected in many" 5 "granulocytes: 3.6;monocytes: 1.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.1;MCF7: 9.0;PC-3: 6.4;SH-SY5Y: 4.3;U-937: 4.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA003825 Approved "Secreted to blood" NA NA 1040000 7000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favorable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" 0.4 0.1 1.4 0.1 1.2 2.6 0.3 0.1 1.3 0.4 0.1 0.5 0.5 0.2 0.0 1.9 0.3 0.1 0.4 1.5 0.8 0.8 604.6 0.6 0.0 0.8 0.6 0.0 0.6 0.1 0.6 0.1 0.9 0.3 0.1 0.0 0.4 0.0 0.0 0.9 0.5 0.0 0.4 1.0 0.1 1.2 0.8 0.0 0.2 0.0 0.1 0.2 0.8 0.8 0.7 1.6 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 1.0 0.0 0.3 0.0 0.2 1.1 0.5 0.3 0.0 7.1 1.4 1.1 0.3 0.7 0.2 0.6 2.4 0.2 1.0 0.0 0.3 0.1 0.2 1.6 0.3 2.5 0.0 9.0 0.1 2.1 0.0 2.1 6.4 0.5 0.2 1.5 0.9 0.0 2.0 4.3 0.2 0.7 0.6 0.0 0.3 0.0 0.0 0.1 0.8 0.0 0.2 0.4 0.0 0.0 0.0 4.6 0.5 0.0 1.2 3.6 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.5 0.0 0.5 1.4 1.2 0.1 1.3 1.5 0.8 0.8 0.6 0.9 0.4 0.8 0.8 0.5 0.0 0.0 0.3 5.3 33.1 7.7 15.3 35.9 0.6 12.7 17.5 1.0 17.2 3.9 1.8 4.2 0.0 4.0 27.6 0.0 6.5 23.3 2.2 0.9 2.2 10.3 19.6 2.6 4.2 0.4 1.1 3.6 1.7 0.0 0.2 16.8 523.0 0.5 0.0 0.8 12.3 8.2 16.7 6.1 42.1 0.6 1.0 8.8 0.0 1.2 0.7 2.1 1.5 0.6 11.1 22.0 0.0 8.5 7.2 60.7 16.1 3.6 0.9 0.0 0.5 1.1 12.0 23.6 57.5 54.3 0.1 4.0 0.1 34.8 7.6 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 232.8;placenta: 489.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 863.3;Langerhans cells: 205.1;Macrophages: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.1;myeloid DC: 179.6" "Group enriched" "Detected in many" 184 "dendritic cells: 179.6;granulocytes: 50.2;monocytes: 141.1" "Cell line enhanced" "Detected in some" "AF22: 24.0;LHCN-M2: 8.9;RH-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 4: Macrophages - Innate immune response" "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 232.8 57.9 2.6 52.3 4.2 16.1 46.9 1.3 13.0 50.4 28.5 45.9 9.7 18.5 5.6 51.2 29.1 52.7 39.2 2.1 3.6 21.0 3.0 38.7 30.0 8.3 4.6 10.7 10.0 13.3 8.1 489.2 6.9 8.8 63.9 21.6 18.8 13.4 10.3 22.7 22.0 89.6 2.6 8.8 25.4 17.8 3.7 20.9 17.1 32.8 12.5 144.5 12.1 4.0 0.0 0.1 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 43.8 0.8 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 50.2 141.1 1.4 0.5 25.4 0.6 0.4 0.3 0.4 179.6 0.4 0.4 0.2 32.9 0.3 0.7 12.5 0.3 364.9 2.6 4.2 1.3 13.0 2.1 3.6 8.3 4.6 6.9 2.6 3.7 4.0 2.0 0.0 1.9 0.3 1.8 18.7 0.0 0.0 0.6 0.1 0.3 0.4 10.6 5.7 0.0 0.0 0.0 5.0 4.5 0.0 0.0 0.0 5.1 0.6 10.6 3.8 0.0 1.3 3.9 0.0 5.6 13.7 0.0 0.4 1.3 0.0 2.9 0.9 863.3 0.0 1.4 0.0 0.0 92.4 205.1 5.8 4.4 232.0 19.6 64.6 53.1 0.9 6.2 0.5 0.7 0.1 0.0 0.7 1.2 0.0 0.0 11.0 2.2 6.5 59.2 2.5 3.3 1.6 0.9 1.2 15.2 10.1 2.6 0.4 0.0 0.1 F13B FXIIIB ENSG00000143278 "Coagulation factor XIII B chain" P05160 1 197038741-197067260 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 211 "liver: 200.2" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 54.9" "Cancer enriched" "Detected in single" 816 "liver cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003827, HPA052139" Supported "Secreted to blood" NA NA 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "HPA003827: AB_1078794, HPA052139: AB_2681744" "unprognostic (1.46e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 200.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 54.9 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719196-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1518 "liver: 1217.3" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 991.0" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 281.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" NA NA 108000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016780: , HPA051476: AB_2681498, HPA054698: AB_2682578" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.2 1217.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.9 0.0 0.2 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.2 281.0 0.0 1.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 0.0 37.5 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 21.8 991.0 0.0 0.0 0.2 0.2 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.0 0.0 0.0 0.1 F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 902.0;Exocrine glandular cells: 464.1;Pancreatic endocrine cells: 1755.7;Peritubular cells: 530.7;Urothelial cells: 497.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1062.0;HaCaT: 490.7;HBEC3-KT: 1270.5;U-2197: 473.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" 118.2 21.3 53.1 28.8 69.9 4.1 70.1 53.2 74.4 48.0 44.1 52.2 36.8 61.1 44.2 41.3 89.9 59.6 36.8 54.0 62.7 18.0 5.1 59.8 12.9 77.7 62.6 114.8 96.5 17.2 81.2 133.4 57.1 56.8 42.1 72.6 93.3 60.4 7.6 56.0 47.3 10.7 60.8 7.2 42.6 34.6 62.0 5.6 62.6 9.9 14.9 65.4 73.0 55.4 1062.0 1.8 2.2 0.5 108.0 53.1 57.2 147.0 87.6 155.4 167.9 18.6 220.6 0.0 73.3 183.5 33.4 490.7 13.2 1270.5 254.4 0.9 1.6 0.0 35.0 3.3 35.9 0.7 0.6 91.9 28.2 73.8 356.5 293.7 1.1 1.1 0.9 0.8 110.0 1.8 1.5 22.3 9.8 6.8 2.2 1.2 10.3 0.5 19.8 3.2 1.3 2.6 117.4 48.3 3.6 29.6 1.3 13.9 0.3 93.7 2.5 473.0 44.6 0.9 1.3 0.9 71.9 5.7 3.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 53.1 69.9 53.2 74.4 54.0 62.7 77.7 62.6 57.1 60.8 62.0 55.4 9.4 131.4 243.3 196.6 0.7 16.3 902.0 359.6 2.2 3.6 29.6 20.4 26.4 18.6 380.3 14.7 0.0 16.5 0.6 20.9 0.0 133.5 8.6 61.3 125.0 13.2 13.1 0.0 0.4 464.1 6.0 125.3 23.0 123.0 2.5 38.1 7.5 0.4 6.1 3.3 4.6 70.3 65.1 2.8 5.2 14.5 281.1 9.1 3.6 45.9 2.1 340.6 0.0 15.6 1.2 1755.7 15.5 530.7 1.2 121.6 10.1 0.4 92.0 16.1 6.6 39.3 76.7 1.7 4.4 6.4 7.5 7.7 7.3 7.9 14.3 497.9 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120685 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "liver: 160.2" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 149.3" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "CACO-2: 11.5;Hep G2: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" NA NA 351000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.2 0.0 0.4 0.1 0.3 0.0 0.2 0.5 0.7 1.1 0.2 0.1 0.5 0.1 0.6 0.1 0.5 0.0 0.2 0.3 0.7 0.4 160.2 0.1 0.0 0.3 0.5 0.4 0.1 0.2 0.4 0.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.4 0.8 0.0 0.2 0.1 0.1 1.5 0.6 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.7 0.3 0.7 0.3 0.5 0.3 0.2 0.6 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.6 0.3 0.5 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.0 8.0 0.3 0.2 0.0 0.4 0.0 0.2 0.0 0.3 2.2 149.3 0.1 0.0 0.5 0.4 0.0 2.8 0.7 0.2 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 1.1 0.3 0.0 0.2 0.0 0.5 0.1 3.2 4.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 F8 "DXS1253E, F8C, FVIII, HEMA" ENSG00000185010 "Coagulation factor VIII" P00451 X 154835788-155026940 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Hemophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.2" "Group enriched" "Detected in many" 10 "Adipocytes: 118.6;Endothelial cells: 120.4;Hepatic stellate cells: 371.2" "Cancer enhanced" "Detected in all" "renal cancer: 7.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB018777 Enhanced "Secreted to blood" NA NA 25000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB018777: AB_640320" "unprognostic (2.09e-1)" "unprognostic (5.66e-4)" "unprognostic (4.94e-2)" "unprognostic (8.32e-5)" "unprognostic (1.26e-1)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" "unprognostic (8.27e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (5.58e-2)" "unprognostic (1.24e-2)" "unprognostic (2.16e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (4.44e-2)" 29.4 15.2 7.8 2.5 8.6 2.1 19.3 7.4 11.2 7.5 9.9 9.6 2.9 10.9 9.1 4.0 7.9 5.0 53.2 8.2 8.5 14.1 20.1 16.7 4.7 8.6 8.4 14.5 11.6 5.6 6.4 3.3 8.6 9.0 3.8 6.2 4.7 7.5 20.6 3.6 5.0 6.3 7.8 17.9 5.7 6.1 8.9 3.2 10.9 28.1 3.7 8.1 3.7 7.8 6.1 4.5 0.9 2.1 6.5 10.1 0.7 2.9 1.8 2.0 3.4 0.3 6.8 12.0 9.5 3.0 4.7 0.8 1.0 1.0 1.8 5.1 1.9 2.4 2.8 0.2 3.0 2.1 5.6 7.2 0.6 1.8 2.4 3.5 1.2 5.7 1.1 9.0 10.0 2.7 1.7 1.9 1.6 1.8 4.5 1.4 1.5 1.8 1.8 1.3 3.7 2.8 7.0 0.8 3.9 1.0 2.1 4.9 1.5 10.3 5.5 16.6 3.7 5.3 5.1 6.0 9.4 12.3 5.5 4.6 2.8 0.9 5.2 2.4 10.3 2.1 3.1 5.5 2.7 1.9 1.6 4.1 4.4 3.3 2.4 0.4 4.6 2.7 7.8 8.6 7.4 11.2 8.2 8.5 8.6 8.4 8.6 7.8 8.9 7.8 118.6 0.0 6.3 13.1 2.3 1.8 2.5 1.6 4.0 8.1 3.7 4.2 17.7 7.2 1.9 3.7 2.1 0.9 2.0 0.6 7.9 3.1 1.4 1.5 1.5 120.4 0.0 8.4 7.2 0.7 0.7 6.8 0.0 1.5 1.3 8.2 371.2 11.8 3.2 6.7 5.0 0.6 0.0 19.9 1.1 3.3 11.5 3.0 0.0 8.4 2.4 6.8 2.1 7.5 6.0 4.5 0.1 5.3 2.0 1.4 0.9 11.4 2.4 3.5 6.6 11.1 13.0 2.3 3.4 1.5 1.1 0.1 4.0 4.3 0.4 2.1 F9 FIX ENSG00000101981 "Coagulation factor IX" P00740 X 139530739-139563459 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2467 "liver: 704.9" "Cell type enriched" "Detected in some" 32 "Hepatocytes: 609.1" "Cancer enriched" "Detected in single" 1354 "liver cancer: 67.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 8200000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: Hepatocytes - Hemostasis" "prognostic favorable (6.69e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 704.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 609.1 0.0 0.0 0.1 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 FAM177A1 C14orf24 ENSG00000151327 "Family with sequence similarity 177 member A1" Q8N128 14 35044907-35113130 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 637.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053222, HPA055440" Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Vesicles Nucleoplasm "HPA053222: AB_2682083, HPA055440: AB_2682817" "unprognostic (6.86e-2)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (4.64e-3)" "unprognostic (6.28e-2)" "unprognostic (7.79e-2)" "prognostic favorable (8.51e-5)" "unprognostic (1.12e-2)" "unprognostic (7.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (1.69e-1)" "unprognostic (8.28e-2)" "unprognostic (1.91e-1)" 45.3 43.2 36.8 30.0 50.1 49.6 38.2 45.3 46.5 44.2 36.9 81.5 57.2 29.4 29.6 49.7 26.8 37.7 78.1 39.0 51.3 61.3 77.0 68.6 20.2 52.4 50.6 28.2 49.4 30.6 47.4 27.3 49.1 63.1 71.5 31.3 43.4 36.1 48.3 41.3 54.6 42.3 45.0 23.6 42.5 86.2 47.0 21.6 48.0 32.8 23.2 46.7 37.7 57.0 63.4 51.2 38.0 31.3 64.6 64.6 46.7 101.3 55.8 52.4 57.1 52.2 82.6 25.1 68.1 98.9 71.1 65.8 47.1 58.5 66.7 73.5 28.8 19.5 63.8 179.5 79.4 30.7 44.9 58.5 75.3 63.5 49.5 76.7 60.6 46.7 47.7 79.8 102.5 91.5 38.0 28.1 30.9 100.9 65.2 21.9 52.7 35.9 95.2 68.7 52.1 45.9 119.3 94.2 81.3 75.2 87.2 23.9 71.3 67.5 59.2 76.6 53.2 59.3 79.8 31.2 42.3 20.5 68.0 79.9 43.9 79.2 31.0 36.7 36.5 45.0 40.3 35.7 34.8 35.8 31.7 31.4 167.5 32.6 31.9 50.8 60.0 30.4 36.8 50.1 45.3 46.5 39.0 51.3 52.4 50.6 49.1 45.0 47.0 57.0 126.7 240.4 176.3 6.5 87.4 160.7 199.4 200.4 83.6 35.8 119.0 118.4 147.8 67.2 168.1 104.8 27.1 71.0 322.2 329.3 119.3 121.9 637.1 235.5 86.6 116.4 133.8 36.0 10.7 249.6 118.0 80.5 107.0 426.4 82.3 43.1 82.5 235.6 75.5 23.5 13.4 189.5 144.5 61.1 130.9 505.9 54.0 85.4 149.4 8.4 125.1 45.3 48.4 9.0 28.4 364.6 220.1 53.0 133.3 211.4 273.7 347.2 177.8 45.5 46.0 65.2 106.2 189.3 106.8 93.1 171.5 123.3 215.7 30.4 224.2 229.5 FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Cardiomyocytes: 6.6;Fibroblasts: 19.7;Hepatic stellate cells: 4.6;Langerhans cells: 9.5;Melanocytes: 7.2;Suprabasal keratinocytes: 4.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2197: 259.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" 3.1 2.7 0.0 0.5 0.1 0.1 3.4 0.1 0.3 2.6 4.2 1.8 0.8 4.7 0.4 4.0 2.0 16.1 15.9 0.3 0.0 4.1 10.2 2.5 0.1 0.0 0.0 7.9 1.3 0.2 0.1 0.2 0.0 0.6 2.0 0.0 1.2 0.2 0.3 3.4 1.3 4.7 0.0 0.6 1.0 0.4 0.0 0.2 2.7 1.3 0.5 4.4 1.3 0.1 0.0 0.1 0.0 0.0 27.8 28.4 0.0 14.9 56.2 0.3 0.2 0.0 0.0 0.0 0.0 57.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.6 0.0 35.6 4.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 57.1 0.0 259.7 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.8 6.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.8 0.0 0.0 0.3 0.0 0.0 19.7 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 0.0 2.8 0.1 7.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 1.8 0.0 0.0 0.1 4.8 0.7 0.2 0.0 0.0 0.0 FAM180B LOC399888 ENSG00000196666 "Family with sequence similarity 180 member B" Q6P0A1 11 47586678-47589194 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.5;brain: 5.9;breast: 5.2;choroid plexus: 5.1;skin 1: 6.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.4;Fibroblasts: 20.4;Langerhans cells: 11.9;Melanocytes: 5.4;Peritubular cells: 4.1;Suprabasal keratinocytes: 6.3" "Cancer enhanced" "Detected in some" "melanoma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029408 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA029408: AB_10601319" "unprognostic (1.28e-2)" "unprognostic (4.99e-3)" "unprognostic (7.48e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.64e-2)" "unprognostic (1.21e-3)" "unprognostic (1.04e-1)" "unprognostic (2.69e-1)" "unprognostic (3.87e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-5)" "unprognostic (5.65e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" 6.5 0.1 0.8 0.0 2.0 0.1 5.2 5.9 1.7 0.4 5.1 0.6 0.0 0.2 0.0 0.1 0.4 0.4 0.7 0.6 0.8 0.0 0.0 0.2 0.0 1.9 1.3 0.1 0.1 0.0 0.2 0.0 1.5 0.0 0.0 0.1 1.1 0.0 1.0 6.3 0.2 0.1 1.3 0.1 0.5 0.5 1.6 0.7 4.3 2.9 0.1 0.4 0.2 2.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.0 5.9 1.7 0.6 0.8 1.9 1.3 1.5 1.3 1.6 2.6 0.8 0.0 0.0 1.0 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 20.4 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.6 11.9 0.3 2.5 0.3 5.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.0 6.3 0.1 0.3 0.0 0.0 0.0 FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 50.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 82.4;Early spermatids: 69.0;Hepatocytes: 66.8;Hofbauer cells: 94.0;Late spermatids: 189.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;BJ hTERT+: 27.3;HSkMC: 21.8;U-2197: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" NA NA 13000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "HPA048964: AB_2680575" "unprognostic (3.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-3)" "unprognostic (2.39e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (9.16e-10)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (2.39e-2)" 7.5 1.6 0.4 2.7 0.3 0.6 5.4 0.3 0.6 17.5 2.6 1.6 0.6 12.5 0.1 3.1 6.0 1.3 3.1 0.1 1.1 12.9 50.2 12.6 1.6 0.8 1.7 8.1 1.0 0.3 6.3 2.2 0.7 2.5 0.4 0.1 11.6 0.6 1.6 2.5 2.0 2.3 0.1 4.5 7.8 6.5 3.6 0.4 6.8 0.1 0.5 2.2 5.7 0.7 0.0 0.2 0.0 0.2 1.1 10.1 0.0 0.5 27.3 0.0 0.0 0.0 0.1 0.0 2.0 2.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.0 21.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.1 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.3 0.3 0.6 0.1 1.1 0.8 1.7 0.7 0.1 3.6 0.7 1.4 16.0 82.4 0.7 1.1 2.3 0.1 5.2 0.0 3.2 5.3 0.9 5.2 7.2 21.3 44.1 0.0 0.6 0.4 0.0 0.0 1.2 69.0 6.1 44.4 3.6 0.0 2.7 3.8 0.5 2.2 18.1 42.3 9.7 1.3 2.9 7.5 66.8 94.0 42.1 8.2 0.0 2.0 27.4 3.5 189.3 11.1 26.8 1.8 16.9 1.3 0.2 0.0 4.0 2.1 0.8 0.0 14.7 0.2 0.0 0.0 15.3 0.8 2.8 6.6 3.4 3.0 1.2 0.6 1.2 1.8 2.7 1.0 13.6 0.0 0.1 FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C golgi associated secretory pathway kinase" Q8IXL6 7 192571-260772 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 55.2;Hepatocytes: 94.0;Hofbauer cells: 54.9;Peritubular cells: 56.4;Proximal tubular cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 55.3;hTERT-RPE1: 39.9;U-87 MG: 36.0;WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Approved "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" NA NA 240000000 "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.94e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (3.15e-2)" "unprognostic (1.03e-2)" "unprognostic (3.33e-3)" "unprognostic (2.47e-2)" "unprognostic (7.86e-2)" "unprognostic (2.45e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (9.40e-6)" "unprognostic (1.97e-3)" "unprognostic (2.49e-1)" "unprognostic (3.08e-3)" "unprognostic (1.94e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (3.83e-3)" 32.5 14.8 7.0 7.3 5.7 1.5 32.8 5.0 7.0 19.4 0.8 44.3 4.5 19.4 2.1 14.3 20.2 5.9 30.2 4.3 5.0 34.9 56.5 27.9 1.1 12.5 9.7 20.3 13.4 1.6 18.3 2.6 6.7 29.9 1.4 1.1 20.3 3.6 30.7 14.7 23.3 6.8 6.4 8.9 38.9 7.8 12.6 0.6 19.6 6.3 0.6 36.8 15.1 6.2 19.6 6.4 0.3 10.3 11.8 20.3 0.0 17.4 23.2 7.9 5.9 0.9 10.1 0.0 9.3 21.8 10.4 14.9 1.1 0.6 1.6 4.5 0.6 0.0 3.1 3.4 8.8 0.0 1.0 55.3 1.6 0.3 0.7 39.9 5.0 0.0 0.0 0.0 1.8 1.9 0.0 0.7 8.9 0.1 0.3 2.3 0.5 0.0 4.9 0.0 4.4 0.2 17.2 0.0 2.3 1.1 9.7 6.5 14.6 10.3 5.3 7.7 5.3 0.0 0.0 0.0 36.0 1.0 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 5.7 5.0 7.0 4.3 5.0 12.5 9.7 6.7 6.4 12.6 6.2 5.0 6.4 5.1 11.8 1.2 10.1 2.3 4.5 1.8 26.9 27.6 18.7 9.9 21.5 1.0 55.2 0.0 0.5 4.6 3.4 5.9 1.8 0.0 4.1 19.0 4.5 11.9 0.4 7.4 4.8 0.5 22.6 13.7 9.5 3.8 3.1 9.3 94.0 54.9 1.7 17.0 5.3 2.0 24.4 9.8 2.6 16.1 34.5 1.8 5.6 10.8 17.1 0.0 8.5 15.3 6.3 3.7 56.4 0.1 6.6 33.7 48.7 3.4 9.0 13.1 8.7 17.3 0.3 1.0 3.5 8.1 0.5 0.9 0.6 9.0 1.9 FAM24A AC073585.4 ENSG00000203795 "Family with sequence similarity 24 member A" A6NFZ4 10 122910610-122913111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 118 "testis: 17.6" "Cell type enriched" "Detected in some" 10 "Early spermatids: 303.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052490 Supported "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA052490: AB_2681851" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 303.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FAM3A "2-19, DXS560S, XAP-7" ENSG00000071889 "FAM3 metabolism regulating signaling molecule A" P98173 X 154506159-154516242 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025016, HPA035268, HPA056991" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" "Secreted to blood" Yes No 15000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB025016: , HPA035268: , HPA056991: AB_2683303" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.19e-2)" "unprognostic (4.73e-2)" "unprognostic (5.19e-2)" "unprognostic (2.54e-2)" "unprognostic (2.57e-2)" "unprognostic (2.53e-1)" "unprognostic (6.27e-2)" "unprognostic (3.42e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (2.74e-1)" "unprognostic (1.41e-1)" "unprognostic (4.04e-1)" "unprognostic (9.71e-2)" 28.4 37.3 43.5 11.3 49.1 11.3 27.6 50.8 51.3 44.6 38.8 35.3 28.0 36.0 7.7 41.3 38.9 8.4 58.7 40.6 45.8 38.6 63.1 26.8 9.4 52.2 47.6 51.5 52.0 14.8 40.9 10.1 47.8 39.1 6.8 6.1 28.5 12.7 36.8 31.1 33.8 7.4 46.9 28.2 36.1 10.0 46.4 12.1 39.9 13.7 5.5 35.8 35.3 58.1 44.4 41.1 10.3 34.5 30.3 15.4 28.8 22.3 15.1 14.8 17.6 19.1 26.2 28.5 109.2 36.8 29.0 31.6 16.2 19.3 3.6 23.4 21.7 11.2 36.9 13.8 47.2 7.6 17.6 19.0 17.5 30.7 21.4 17.7 10.5 18.1 21.6 20.5 17.3 46.3 14.2 32.7 4.6 47.8 52.4 17.3 10.4 79.6 16.6 18.0 20.4 15.6 10.3 24.4 37.3 7.4 18.7 11.8 12.0 19.9 12.0 54.7 30.6 77.6 46.5 36.0 36.4 19.6 20.8 23.4 10.8 15.2 13.4 12.7 13.2 6.1 8.6 9.6 11.0 8.7 10.0 12.0 5.8 10.6 11.3 14.6 9.1 10.1 43.5 49.1 50.8 51.3 40.6 45.8 52.2 47.6 47.8 46.9 46.4 58.1 23.5 12.8 16.7 13.1 16.9 16.3 23.4 29.2 22.8 25.4 21.9 24.9 21.9 22.8 16.3 22.0 14.6 47.0 19.3 60.2 27.4 27.6 1.0 13.4 18.3 18.3 17.5 29.9 7.1 42.5 50.0 28.4 50.0 15.0 5.7 34.8 23.6 30.3 29.8 21.9 9.4 58.9 18.3 16.4 15.3 2.8 33.5 18.0 33.8 6.5 17.6 28.9 24.7 11.1 14.3 28.2 57.5 29.3 32.5 28.7 116.2 33.1 12.7 20.4 6.6 26.7 24.5 5.2 10.1 32.1 21.2 71.3 19.3 23.7 39.7 22.9 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 142.6;pancreas: 212.3;salivary gland: 119.4;stomach 1: 114.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 304.6;Exocrine glandular cells: 399.9;Proximal enterocytes: 831.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in some" "CACO-2: 19.5;CAPAN-2: 11.7;Hep G2: 32.1;OE19: 27.3;RPMI-8226: 80.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" NA NA 2080000 250000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 1.5 0.1 0.0 2.5 0.1 0.8 17.7 0.1 0.3 4.9 1.3 5.9 142.6 0.3 22.1 56.2 17.2 16.2 0.6 0.1 0.1 17.9 2.6 9.3 1.5 0.1 0.1 0.2 212.3 0.5 5.4 15.2 0.1 37.9 0.1 0.0 119.4 8.7 0.1 2.3 135.0 0.5 0.1 0.6 114.9 6.9 0.1 3.1 8.0 0.0 16.8 34.4 16.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 19.5 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.9 27.3 0.0 0.2 0.0 80.6 0.0 5.8 0.4 0.4 0.0 0.7 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 1.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 22.4 25.7 0.0 0.8 1.3 17.0 2.9 1.2 0.0 101.3 123.1 0.2 102.9 36.5 66.2 0.0 304.6 1.4 2.7 25.4 172.1 25.2 0.2 0.1 2.5 0.0 0.0 0.1 399.9 11.1 3.4 147.3 0.7 1.3 0.6 0.4 0.3 27.0 0.0 0.1 120.9 42.7 5.0 15.8 11.5 0.6 3.9 5.4 1.9 2.1 0.0 0.0 0.0 0.1 144.6 169.0 0.4 0.2 64.9 831.6 0.7 22.4 0.0 0.0 0.4 1.8 28.0 8.1 29.1 1.3 161.3 0.9 0.0 125.2 130.5 FAM3C "GS3876, ILEI" ENSG00000196937 "FAM3 metabolism regulating signaling molecule C" Q92520 7 121348878-121396364 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 415.8;Urothelial cells: 425.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "memory B-cell: 22.5;naive B-cell: 19.9" "Lineage enriched" "Detected in many" 7 "B-cells: 22.5" "Cell line enhanced" "Detected in all" "CAPAN-2: 1257.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043376, HPA050548" Enhanced Enhanced "Golgi apparatus" "Secreted in other tissues" NA NA 48000000 "Cluster 37: B-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus" "HPA043376: AB_2678452, HPA050548: AB_2681169" "unprognostic (9.44e-2)" "unprognostic (3.91e-1)" "unprognostic (1.75e-1)" "unprognostic (8.11e-3)" "unprognostic (1.26e-2)" "unprognostic (3.09e-3)" "unprognostic (3.38e-3)" "unprognostic (2.44e-1)" "unprognostic (2.95e-1)" "unprognostic (1.22e-2)" "unprognostic (2.15e-3)" "unprognostic (1.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.48e-1)" "unprognostic (9.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" 40.4 45.9 23.8 38.5 26.8 9.6 42.1 20.4 46.5 96.5 15.9 46.5 177.0 51.4 57.5 32.0 34.5 35.3 64.0 33.8 22.6 62.9 49.5 34.5 44.6 29.3 20.7 36.7 74.0 57.3 29.6 44.5 30.4 31.7 54.0 47.8 38.1 32.3 19.0 32.2 158.2 44.3 19.1 47.4 61.8 24.5 21.8 17.1 111.1 24.5 44.8 56.6 31.3 25.4 133.1 33.2 60.7 64.9 100.3 164.2 55.6 139.7 61.5 41.2 52.1 26.4 1257.1 125.4 65.4 72.5 116.7 85.2 35.1 77.7 87.3 15.3 72.5 35.6 19.3 27.4 73.5 59.0 65.3 165.7 52.1 58.9 57.1 110.4 74.8 24.6 23.3 152.3 326.6 22.3 24.6 45.2 108.1 45.4 45.3 34.2 63.8 51.1 256.7 75.1 38.6 38.1 41.4 167.4 80.6 126.2 24.0 32.5 178.8 105.1 37.7 236.1 96.9 148.0 71.3 48.7 114.0 60.6 192.5 0.0 1.1 0.8 2.1 1.2 2.0 22.5 0.9 1.7 1.0 19.9 1.3 0.9 0.2 3.0 0.9 1.5 0.7 0.8 23.8 26.8 20.4 46.5 33.8 22.6 29.3 20.7 30.4 19.1 21.8 25.4 49.8 9.6 33.3 17.3 103.0 71.8 257.1 183.0 61.5 137.3 47.5 28.8 65.7 71.4 134.4 55.2 22.9 88.1 44.8 66.8 60.7 182.2 3.5 76.0 81.8 58.9 52.3 10.3 64.6 191.0 188.6 104.3 46.4 170.1 19.7 33.3 50.0 37.0 43.6 45.4 64.3 49.1 101.7 29.6 88.4 6.7 96.0 30.9 99.6 24.4 31.7 49.4 58.7 42.3 24.7 415.8 71.9 95.9 129.8 325.0 327.0 66.8 63.9 67.1 72.3 93.6 68.7 23.8 22.4 61.7 66.3 120.4 44.3 35.6 86.7 425.8 FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 264.8;intestine: 488.7;salivary gland: 468.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 794.8;Intestinal goblet cells: 1150.1;Paneth cells: 776.7;Proximal enterocytes: 353.1;Undifferentiated cells: 760.0" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 151.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Cell line enriched" "Detected in some" 65 "OE19: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" NA NA 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA013844: AB_2668897" "prognostic favorable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" 0.9 0.1 0.2 29.6 0.1 0.0 18.5 0.0 0.5 31.3 0.1 362.0 89.2 0.6 0.2 264.8 0.8 81.6 0.2 0.2 0.1 1.1 0.2 4.8 0.6 0.1 0.2 0.1 1.7 0.0 0.4 1.0 0.1 14.8 488.7 0.0 468.4 68.4 0.1 2.6 90.4 8.3 0.1 0.2 78.2 0.3 0.3 0.4 1.5 0.0 41.1 12.7 59.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.1 0.4 0.2 68.5 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.2 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.7 0.0 0.3 0.0 0.0 0.4 0.2 0.1 0.0 0.5 0.2 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.6 0.0 1.1 0.3 3.4 0.0 9.9 223.1 0.0 0.0 29.5 53.8 0.2 47.1 133.4 14.7 0.0 0.0 1.3 794.8 0.0 1.3 0.5 0.0 0.0 2.5 152.1 0.0 0.1 0.0 0.0 0.8 114.2 0.2 8.9 0.0 0.4 0.2 0.3 0.0 0.1 1150.1 18.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 776.7 0.0 0.2 68.2 353.1 1.2 43.1 0.0 0.0 0.0 4.9 0.1 0.6 7.9 0.1 0.4 2.0 0.0 760.0 245.0 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 14 "dendritic cells: 43.4;NK-cells: 79.3;T-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" 0.3 0.8 0.1 1.0 0.2 2.8 0.6 0.1 0.2 0.4 0.1 0.8 1.9 0.5 0.7 0.3 0.3 1.1 0.3 0.2 0.1 0.3 1.1 2.0 5.7 0.3 0.2 0.3 0.1 0.0 0.1 0.2 0.2 0.5 0.9 0.0 0.9 0.3 0.1 0.4 1.4 0.3 0.0 4.1 1.5 0.2 0.1 0.6 0.2 0.0 1.8 0.8 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 58.1 0.2 35.5 0.0 11.5 31.4 0.1 0.0 2.2 25.0 1.9 41.5 0.1 0.0 0.2 14.9 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.4 0.4 0.0 2.5 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 43.4 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.6 1.8 0.0 0.9 0.0 79.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 28.8 0.0 0.0 0.1 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FBN2 "CCA, DA9" ENSG00000138829 "Fibrillin 2" P35556 5 128257909-128659185 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 81.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 298.1;Syncytiotrophoblasts: 163.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 5 "monocytes: 2.2" "Cell line enhanced" "Detected in many" "HHSteC: 134.1;HSkMC: 94.3;hTERT-HME1: 215.2;HUVEC TERT2: 122.3" "Region enhanced" "Detected in single" "olfactory bulb: 2.0" "Low region specificity" "Detected in many" "HPA012853, CAB026401" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 11000000 "Cluster 14: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "CAB026401: , HPA012853: AB_1848588" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (7.29e-3)" "unprognostic (1.79e-3)" "unprognostic (6.74e-2)" "unprognostic (2.33e-1)" "unprognostic (4.92e-3)" "unprognostic (9.41e-2)" "unprognostic (1.06e-2)" "unprognostic (4.66e-1)" "unprognostic (1.12e-1)" "unprognostic (8.69e-2)" "unprognostic (8.60e-5)" "unprognostic (1.04e-2)" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (7.41e-5)" 0.1 5.1 0.4 0.8 0.5 3.1 0.2 0.0 0.3 2.2 3.0 0.8 0.3 1.7 0.1 0.1 0.4 0.3 5.5 0.2 0.6 0.1 0.1 0.2 0.5 1.1 1.9 0.5 0.2 0.0 0.8 81.9 0.5 0.8 1.2 0.9 0.3 0.4 0.2 0.2 0.4 1.3 0.5 0.4 0.8 7.4 0.8 0.2 0.5 0.4 0.9 0.5 0.7 0.3 0.0 16.4 58.2 0.0 9.4 16.6 11.8 62.8 0.0 56.0 41.8 0.2 0.0 0.0 0.1 85.5 0.0 9.2 37.6 9.8 52.7 0.1 13.8 0.0 27.3 0.2 134.1 8.4 0.0 94.3 5.3 24.1 215.2 17.9 122.3 0.0 0.0 0.0 35.8 0.1 0.0 3.4 24.5 0.0 18.2 19.2 18.1 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.6 48.0 0.0 18.7 0.0 22.1 41.9 66.8 0.3 0.0 0.0 0.0 6.9 0.0 23.8 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.2 0.6 1.1 1.9 0.5 0.5 0.8 0.3 0.1 0.0 0.5 1.6 0.2 0.0 0.1 1.2 0.6 0.0 0.3 0.3 12.7 0.0 1.4 0.0 0.0 298.1 0.0 0.0 0.0 0.3 3.8 10.0 3.9 1.0 0.0 0.0 1.1 0.0 24.3 8.8 0.0 4.7 0.0 0.1 0.0 0.0 34.0 0.0 50.5 0.0 0.0 10.7 0.4 7.2 1.2 2.7 1.8 1.9 6.2 3.8 0.0 17.6 1.5 0.1 0.0 2.2 0.0 2.0 0.0 0.2 1.6 0.1 6.6 0.1 3.5 10.7 3.5 0.1 0.4 163.5 0.1 8.4 0.1 0.1 FBN3 KIAA1776 ENSG00000142449 "Fibrillin 3" Q75N90 19 8065402-8149592 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.4;salivary gland: 4.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Cardiomyocytes: 2.4;Inhibitory neurons: 3.4;Oligodendrocyte precursor cells: 17.1" "Cancer enhanced" "Detected in many" "testis cancer: 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;CACO-2: 3.7;NTERA-2: 12.3;REH: 18.6;SuSa: 4.5" "Not detected" "Not detected" HPA049482 Uncertain "Secreted to extracellular matrix" NA NA 2400000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA049482: AB_2680786" "unprognostic (9.66e-3)" "unprognostic (5.15e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (4.14e-2)" "unprognostic (5.14e-3)" "unprognostic (6.26e-2)" "unprognostic (4.10e-3)" "unprognostic (3.17e-2)" "unprognostic (8.94e-2)" "unprognostic (4.61e-2)" "unprognostic (1.53e-1)" "unprognostic (2.76e-2)" "unprognostic (1.34e-2)" "unprognostic (2.57e-1)" "unprognostic (1.17e-2)" "unprognostic (3.17e-1)" 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.5 0.0 0.1 0.3 0.6 2.4 0.1 1.4 0.0 0.5 0.6 0.1 0.0 0.0 0.7 0.0 0.6 0.9 0.1 0.0 4.0 0.0 0.3 0.2 0.1 0.1 0.5 0.0 0.1 0.5 0.6 0.5 1.9 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 3.7 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 12.3 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.5 0.3 0.6 0.5 0.6 0.6 0.5 0.6 0.6 0.0 6.4 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 17.1 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 FCER2 "CD23, CD23A, CLEC4J, FCE2" ENSG00000104921 "Fc fragment of IgE receptor II" P06734 19 7688758-7702146 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgE-binding protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 42.2" "Cell type enriched" "Detected in some" 16 "B-cells: 157.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in many" 24 "memory B-cell: 200.9;naive B-cell: 496.2" "Lineage enriched" "Detected in many" 34 "B-cells: 496.2" "Cell line enriched" "Detected in some" 14 "HDLM-2: 449.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002624, HPA008928, HPA067430" Enhanced "Secreted to blood" NA NA 240000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "CAB002624: , HPA008928: AB_1846285, HPA067430: " "unprognostic (3.20e-4)" "unprognostic (1.87e-3)" "unprognostic (1.95e-2)" "unprognostic (2.44e-2)" "unprognostic (4.77e-2)" "unprognostic (1.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.89e-3)" "unprognostic (2.71e-1)" "unprognostic (1.88e-1)" "unprognostic (2.04e-2)" "unprognostic (8.55e-2)" "unprognostic (2.46e-4)" "unprognostic (2.99e-1)" "unprognostic (1.80e-1)" "unprognostic (4.89e-2)" "unprognostic (5.17e-2)" 4.8 0.1 0.0 17.4 0.0 5.2 1.2 0.2 1.3 0.4 0.0 1.8 2.8 0.1 0.1 0.4 0.3 1.1 0.5 0.3 0.0 0.3 0.5 0.6 39.5 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.1 1.9 0.0 1.8 0.1 0.3 0.4 9.7 0.2 0.0 38.4 2.2 0.4 0.0 6.3 0.6 0.1 42.2 1.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 449.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 0.1 32.7 0.0 0.5 4.2 0.3 0.0 14.7 0.1 200.9 0.2 0.0 4.4 496.2 0.3 0.1 1.5 0.3 4.4 0.6 0.2 21.6 0.0 0.0 0.2 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 157.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.1 0.0 1.2 0.0 0.1 0.0 0.0 1.3 1.7 0.0 0.0 9.4 1.8 1.0 0.9 0.0 2.1 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 1.2 1.2 0.0 0.0 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCGR3B "CD16, CD16b, FCG3, FCGR3" ENSG00000162747 "Fc fragment of IgG receptor IIIb" O75015 1 161623196-161631963 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.6;lymphoid tissue: 82.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Club cells: 3.1;dendritic cells: 2.2;Fibroblasts: 2.2;Kupffer cells: 2.2;Macrophages: 4.3;NK-cells: 2.1;Respiratory ciliated cells: 2.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.7" "Immune cell enriched" "Detected in many" 79 "neutrophil: 7208.7" "Lineage enriched" "Detected in many" 79 "granulocytes: 7208.7" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (1.60e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-3)" "unprognostic (4.16e-2)" "unprognostic (1.15e-1)" "unprognostic (6.52e-2)" "unprognostic (3.97e-2)" "unprognostic (6.96e-3)" "unprognostic (2.53e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (8.67e-2)" "unprognostic (5.16e-2)" "unprognostic (1.35e-1)" "unprognostic (8.37e-3)" "unprognostic (2.28e-1)" "unprognostic (9.24e-2)" 23.0 2.8 0.6 76.4 1.2 36.6 1.3 0.7 6.7 2.8 1.1 2.1 0.5 0.9 0.0 5.0 5.2 16.4 3.5 0.6 0.7 1.9 7.9 22.0 1.3 1.0 0.8 0.4 4.0 1.4 0.7 9.1 2.7 0.8 0.9 0.0 1.3 0.4 0.8 4.0 2.4 5.6 0.7 82.0 1.8 0.2 1.1 6.1 1.3 23.0 1.5 18.3 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.1 12.5 17.2 30.4 0.6 0.3 0.9 6.9 3.0 0.6 0.5 6.2 7208.7 3.6 90.8 0.4 0.6 18.5 0.6 1.2 0.7 6.7 0.6 0.7 1.0 0.8 2.7 0.7 1.1 1.1 0.0 3.2 7.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 1.5 3.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.3 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 2.2 0.0 0.9 0.0 4.3 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 FCMR "FAIM3, TOSO" ENSG00000162894 "Fc fragment of IgM receptor" O60667 1 206903317-206923247 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 65.5;lymphoid tissue: 180.6" "Cell type enhanced" "Detected in many" "B-cells: 262.3;dendritic cells: 43.5;NK-cells: 108.1;T-cells: 74.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "RPMI-8226: 171.4;U-266/70: 73.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003910 Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 5500000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA003910: AB_1078798" "prognostic favorable (4.23e-4)" "unprognostic (1.16e-3)" "unprognostic (7.48e-2)" "unprognostic (3.06e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-3)" "unprognostic (1.15e-1)" "unprognostic (4.85e-3)" "unprognostic (1.03e-1)" "unprognostic (3.97e-1)" "unprognostic (3.23e-2)" "unprognostic (2.01e-1)" "unprognostic (8.15e-3)" "unprognostic (8.06e-2)" "unprognostic (2.12e-2)" "unprognostic (3.74e-2)" "unprognostic (5.05e-3)" 4.9 1.5 0.3 74.8 0.3 12.6 2.4 0.3 0.8 1.5 0.4 8.0 6.1 2.4 2.6 3.0 1.9 11.3 2.6 0.1 0.4 2.3 5.9 6.0 152.1 0.4 0.1 0.8 1.1 0.5 1.0 1.8 0.2 3.4 9.9 0.2 3.5 1.2 3.6 0.4 65.5 2.3 0.0 115.0 14.2 0.5 0.5 77.2 3.3 1.4 180.6 19.1 1.6 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 3.4 0.3 0.3 0.0 0.0 11.6 0.0 0.4 0.7 0.3 0.0 0.6 0.5 0.0 0.2 0.2 0.9 0.0 1.6 0.1 0.0 0.1 0.7 0.3 1.2 0.0 0.0 7.0 0.2 23.5 0.0 0.2 3.5 0.3 0.1 0.0 0.2 4.9 0.6 171.4 0.1 0.3 0.1 0.0 2.8 0.6 13.0 0.0 0.3 0.0 0.5 0.0 0.5 0.2 0.1 73.8 5.9 23.2 0.8 0.1 0.6 7.9 2.8 3.6 209.3 4.3 276.9 882.3 280.1 266.3 3.2 1057.5 483.2 336.0 56.0 218.8 4.3 13.7 687.7 416.6 0.3 0.3 0.3 0.8 0.1 0.4 0.4 0.1 0.2 0.0 0.5 0.6 1.3 0.0 3.9 0.0 262.3 0.0 4.9 0.0 1.2 0.0 3.5 3.0 3.6 5.7 1.3 0.0 0.0 0.1 43.5 0.9 0.0 1.7 0.2 0.8 0.7 1.7 0.0 8.4 0.0 2.9 0.1 3.4 4.1 0.9 0.0 0.6 4.6 1.4 4.4 0.0 0.0 0.6 0.0 5.7 0.0 0.4 0.3 8.1 0.0 0.0 3.6 0.0 108.1 0.0 0.0 1.2 0.3 0.0 30.5 2.9 0.1 1.0 0.7 0.0 0.0 0.2 2.9 0.1 2.3 1.7 0.0 0.0 74.9 0.0 1.9 6.8 FCN1 FCNM ENSG00000085265 "Ficolin 1" O00602 9 134903232-134917912 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 158.9;lung: 46.2;lymphoid tissue: 96.3" "Group enriched" "Detected in many" 10 "Kupffer cells: 504.4;Macrophages: 542.4;monocytes: 1017.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "classical monocyte: 1699.8;intermediate monocyte: 1195.1" "Lineage enhanced" "Detected in all" "monocytes: 1699.8" "Group enriched" "Detected in some" 5 "NB-4: 4.7;U-937: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000685, HPA001295, CAB016760" Enhanced "Secreted to blood" NA NA 1060000000 36000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB016760: , HPA000685: AB_1078840, HPA001295: AB_1078842" "unprognostic (1.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.14e-3)" "unprognostic (1.34e-1)" "unprognostic (9.91e-2)" "unprognostic (1.62e-3)" "unprognostic (3.66e-3)" "unprognostic (2.21e-1)" "unprognostic (1.14e-1)" "unprognostic (5.59e-2)" "unprognostic (2.49e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.73e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.28e-1)" 15.9 1.4 0.6 47.7 0.5 158.9 5.1 0.8 0.7 2.0 0.5 3.2 0.5 1.5 0.0 1.6 6.4 3.9 5.1 0.5 0.3 4.1 7.2 46.2 3.2 0.5 0.5 1.0 2.5 0.1 1.0 2.4 0.6 2.3 1.6 0.1 2.8 0.5 1.6 1.2 2.8 12.1 0.2 96.3 3.7 0.7 0.7 2.4 2.2 1.1 1.3 10.1 2.3 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.1 0.0 0.1 0.0 7.2 0.1 9.3 1699.8 18.0 2.9 1195.1 3.5 5.9 1.4 1.6 492.6 1.5 1.7 1.6 277.1 2.8 582.2 13.0 2.1 1796.8 0.6 0.5 0.8 0.7 0.5 0.3 0.5 0.5 0.6 0.2 0.7 0.5 2.1 6.4 17.1 0.0 6.6 1.9 0.2 0.0 0.0 0.0 0.3 0.0 2.6 1.5 5.0 1.8 0.0 0.8 6.0 0.1 0.0 0.0 0.1 0.2 0.2 2.7 0.0 5.2 0.0 0.0 1.5 3.6 1.5 0.1 12.6 0.1 3.9 2.6 68.4 0.0 0.0 0.0 0.0 504.4 68.3 0.0 0.0 542.4 0.0 0.0 1017.8 0.0 27.8 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 2.1 0.7 0.0 0.0 1.0 0.5 0.0 0.1 0.2 0.4 1.1 6.1 0.3 0.0 0.2 FCN2 "EBP-37, FCNL, ficolin-2, P35" ENSG00000160339 "Ficolin 2" Q15485 9 134880810-134887523 "Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 99.7" "Cell type enriched" "Detected in some" 18 "Hepatic stellate cells: 1192.6" "Group enriched" "Detected in some" 8 "breast cancer: 1.0;liver cancer: 2.0;prostate cancer: 1.1;renal cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5;intermediate monocyte: 4.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in some" 23 "spinal cord: 38.6" "Secreted to blood" NA NA 8100000000 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-4)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.81e-1)" "unprognostic (2.82e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.07e-1)" 4.7 24.6 0.4 0.0 0.4 0.1 7.6 0.3 0.5 0.3 0.5 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.3 0.6 0.4 6.4 99.7 0.1 0.1 0.3 0.5 0.5 0.5 0.2 3.1 0.0 0.4 3.2 0.0 0.0 3.2 0.4 0.1 0.2 0.1 0.0 0.2 3.1 0.2 0.2 0.4 0.0 2.1 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.5 0.0 0.0 4.6 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.1 0.0 2.2 0.0 0.0 9.0 0.4 0.4 0.3 0.5 0.6 0.4 0.3 0.5 0.4 0.2 0.4 0.3 0.1 0.0 0.0 0.7 3.8 0.0 0.1 0.0 0.0 0.0 3.8 0.4 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 34.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1192.6 12.6 0.0 0.0 0.1 0.0 0.0 64.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 278.3;lung: 724.6" "Cell type enriched" "Detected in some" 16 "Hepatic stellate cells: 2828.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025945 Approved "Secreted to blood" NA NA 22800000000 14000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025945: " "unprognostic (1.59e-1)" "unprognostic (5.25e-2)" "unprognostic (1.55e-2)" "unprognostic (8.27e-2)" "unprognostic (1.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.87e-3)" "unprognostic (1.21e-1)" "unprognostic (6.28e-4)" "unprognostic (7.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-2)" 62.6 35.9 1.1 5.7 1.0 0.0 40.8 1.1 1.6 2.7 10.0 4.1 0.8 3.9 0.1 2.8 3.0 1.6 62.1 1.4 1.1 55.2 278.3 724.6 4.3 1.2 1.2 2.4 12.5 2.7 6.6 22.6 1.2 5.3 0.5 0.0 2.5 0.5 9.0 1.9 6.7 1.8 1.2 11.3 8.4 2.4 1.2 0.4 20.4 7.5 0.3 3.0 1.9 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 1.1 1.6 1.4 1.1 1.2 1.2 1.2 1.2 1.2 1.0 94.1 0.0 9.3 0.0 16.6 0.8 0.6 0.5 0.6 0.0 0.8 2.8 2.4 52.9 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.5 0.4 0.2 155.1 0.0 136.4 0.1 0.0 0.0 3.8 0.5 0.2 3.8 0.0 2828.6 31.8 0.3 0.0 0.1 0.0 2.0 168.6 0.3 2.7 3.4 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.1 5.1 0.0 0.0 1.0 2.7 0.5 0.5 1.0 1.1 0.0 4.9 0.5 0.0 0.3 FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 5 "B-cells: 102.6;Early spermatids: 63.6;Plasma cells: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 5 "U-266/70: 3.4;U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" 0.4 0.4 0.0 13.8 0.0 2.3 2.4 0.0 0.1 0.6 0.0 5.5 5.8 0.1 0.3 0.8 0.4 1.2 0.3 0.0 0.0 0.4 0.3 1.1 24.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 4.4 0.0 3.8 0.3 0.0 0.0 5.0 0.1 0.1 15.1 4.5 0.6 0.0 4.1 0.6 0.0 36.3 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 102.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.1 2.9 0.1 0.0 0.0 63.6 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.3 1.1 0.0 1.3 0.0 0.4 1.8 0.3 0.0 0.1 0.0 0.0 0.3 0.3 10.1 0.3 0.2 23.2 0.0 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 190.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.3 1.2 0.1 0.1 0.0 0.7 5.7 0.0 0.6 0.0 FDCSP "C4orf7, FDC-SP" ENSG00000181617 "Follicular dendritic cell secreted protein" Q8NFU4 4 70226124-70235252 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "lymphoid tissue: 3257.5;salivary gland: 6608.7" "Group enriched" "Detected in some" 25 "Breast glandular cells: 90.8;Breast myoepithelial cells: 87.9;Ductal cells: 75.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 336.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.6;GAMG: 7.5;HL-60: 1.5;K-562: 1.4;RH-30: 2.1;U-87 MG: 5.4" "Not detected" "Not detected" "HPA014326, CAB014890" Enhanced "Secreted in other tissues" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" "CAB014890: , HPA014326: AB_1845719" "unprognostic (1.26e-3)" "unprognostic (2.32e-1)" "unprognostic (8.73e-3)" "unprognostic (9.62e-2)" "prognostic favorable (2.38e-4)" "unprognostic (5.99e-3)" "prognostic favorable (1.32e-4)" "unprognostic (2.04e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.79e-1)" "unprognostic (1.96e-1)" "unprognostic (3.68e-2)" "unprognostic (2.80e-1)" "unprognostic (7.83e-2)" 4.8 1.8 0.0 313.8 0.0 0.0 183.5 0.0 0.0 0.2 0.2 24.6 1.8 4.8 0.1 13.4 0.9 2.7 1.6 0.0 0.1 0.3 1.9 1.4 1052.7 0.1 0.6 0.5 2.7 0.0 0.5 0.7 0.0 1.6 18.3 0.0 6608.7 0.1 1.4 0.5 49.5 4.2 0.0 33.2 10.1 0.3 0.3 17.2 3.3 0.0 3257.5 11.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.1 5.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 90.8 87.9 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 75.6 0.0 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 234.6" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 47.2" "Cancer enriched" "Detected in some" 12 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" NA NA 47500000000 3600000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA035132: AB_10601650, HPA035133: " "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.62e-1)" "unprognostic (8.74e-2)" "unprognostic (6.28e-3)" "unprognostic (1.24e-2)" "unprognostic (7.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (9.18e-2)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.6 0.0 0.1 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.4 234.6 0.0 0.0 0.1 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.8 0.0 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.9 0.0 5.3 0.2 0.2 0.1 0.0 2.7 0.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.7 47.2 0.0 0.0 0.0 0.2 0.0 2.9 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583128-154590745 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 388 "liver: 18396.9" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 17365.8" "Cancer enriched" "Detected in many" 43 "liver cancer: 2431.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 429.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 407000000 140000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB016776: , HPA051370: AB_2681458, HPA064755: AB_2685345" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.29e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.23e-6)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" 2.1 1.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.5 0.0 0.6 0.6 0.7 0.9 13.2 1.2 0.0 0.0 18.8 18396.9 5.3 0.1 0.0 0.0 0.7 18.8 0.0 0.5 0.9 0.0 0.4 0.0 0.0 0.5 0.0 0.5 0.6 0.9 0.0 0.0 9.9 47.4 3.7 0.0 0.1 0.4 0.0 0.1 0.6 0.7 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 2.7 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.4 0.1 429.3 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.5 6.1 0.0 0.0 0.5 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 1.0 0.0 1.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 414.6 3.2 0.0 0.0 0.0 0.0 0.0 1.9 38.6 28.3 0.1 0.2 8.1 0.0 205.9 0.0 1.8 0.1 0.1 1.1 1.3 0.0 0.0 238.8 17365.8 0.1 0.0 0.0 0.0 0.0 328.3 0.0 46.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 1.2 0.0 0.0 0.0 2.3 9.5 0.0 0.0 0.0 0.1 17.4 0.7 0.0 0.0 0.1 17.6 0.0 0.0 0.0 FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 373 "liver: 17944.9" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 17273.6" "Cancer enriched" "Detected in many" 42 "liver cancer: 2262.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 249.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 110000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB008624: AB_1615610, HPA001900: AB_1078865, HPA001901: AB_1078864" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (4.65e-2)" "unprognostic (3.44e-1)" "unprognostic (2.20e-3)" "unprognostic (1.42e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.48e-2)" "unprognostic (7.91e-2)" 2.0 0.8 0.0 0.0 0.0 0.1 2.8 0.0 0.0 1.3 0.0 0.5 0.0 0.6 0.3 0.6 0.8 0.4 1.4 0.0 0.0 48.0 17944.9 0.5 0.1 0.0 0.0 0.6 3.3 0.0 0.5 1.0 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.5 1.2 0.0 0.0 12.1 6.8 0.5 0.0 0.3 0.4 0.0 0.1 0.5 0.7 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.2 0.1 249.9 0.0 5.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.8 0.0 0.9 0.0 2.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 39.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 251.6 0.0 3.7 0.0 0.0 0.0 0.0 1.9 10.6 0.5 0.6 0.8 13.1 1.8 302.1 0.0 3.8 0.2 0.0 0.0 5.9 0.0 0.0 318.1 17273.6 0.3 0.0 0.0 0.0 0.0 421.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.7 0.0 0.0 0.0 FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 295.2;choroid plexus: 125.8" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Cardiomyocytes: 62.4;Muller glia cells: 69.4;Oligodendrocytes: 119.8" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.6;BJ hTERT+: 33.0;BJ hTERT+ SV40 Large T+: 35.9;BJ hTERT+ SV40 Large T+ RasG12V: 45.0;HBF TERT88: 64.3;hTEC/SVTERT24-B: 45.4;LHCN-M2: 30.6;U-2 OS: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" 17.9 3.3 206.3 1.6 259.3 1.1 12.5 213.9 295.2 1.3 125.8 2.4 1.0 3.1 7.9 2.0 1.7 2.5 50.2 183.5 245.5 66.5 1.7 2.8 1.2 236.2 237.7 0.9 0.8 4.3 6.5 2.1 259.9 1.8 1.3 18.8 7.3 2.3 2.2 1.7 1.2 2.5 225.4 6.9 0.8 2.0 244.3 1.5 5.6 7.8 2.0 1.2 1.0 272.8 5.6 0.3 0.3 1.5 1.1 3.3 1.8 44.6 33.0 35.9 45.0 0.2 0.2 1.3 3.1 15.4 2.1 0.7 0.0 3.5 64.3 0.2 0.0 0.0 0.8 0.4 0.6 0.0 0.4 1.6 1.1 45.4 2.7 9.7 0.0 0.2 0.0 1.6 30.6 0.7 0.1 0.9 1.4 0.1 1.4 0.2 1.5 0.6 1.5 0.2 1.1 2.3 0.1 0.9 0.6 8.0 0.0 0.2 1.1 5.8 33.0 0.8 21.3 0.8 0.4 0.3 8.2 0.3 1.6 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.2 0.1 0.0 206.3 259.3 213.9 295.2 183.5 245.5 236.2 237.7 259.9 225.4 244.3 272.8 1.4 0.0 0.0 75.1 0.1 0.4 5.0 5.7 7.4 3.5 1.2 25.4 62.4 0.0 2.1 20.2 16.7 1.1 0.1 0.0 0.0 1.1 0.4 0.0 0.7 4.8 0.0 0.0 13.0 0.0 0.5 4.7 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 14.6 0.0 12.2 0.0 0.0 1.4 0.0 0.2 3.6 29.0 0.0 69.4 0.0 15.1 119.8 0.6 0.0 0.4 0.0 5.3 0.0 0.3 0.1 11.6 6.6 0.5 23.4 0.1 0.1 0.6 0.0 0.8 0.4 0.0 0.0 0.7 FGF10 ENSG00000070193 "Fibroblast growth factor 10" O15520 5 44300247-44389706 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant, Ectodermal dysplasia, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 21.6;Fibroblasts: 14.6;Leydig cells: 8.4;Muller glia cells: 4.3;Peritubular cells: 10.5" "Cancer enriched" "Detected in some" 6 "breast cancer: 5.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "AF22: 27.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB010315 Uncertain "Secreted in other tissues" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "CAB010315: AB_2262731" "unprognostic (1.40e-1)" "unprognostic (1.25e-1)" "unprognostic (8.54e-2)" "unprognostic (1.08e-1)" "unprognostic (3.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.54e-2)" "unprognostic (4.06e-3)" "unprognostic (2.72e-2)" "unprognostic (6.73e-2)" "unprognostic (5.59e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.14e-2)" "unprognostic (5.23e-4)" 13.9 1.6 0.3 2.6 0.9 0.0 15.2 0.5 0.7 14.6 1.1 7.0 0.4 2.4 4.4 1.4 8.5 2.8 0.7 0.6 0.7 0.7 0.1 2.6 0.6 1.3 1.9 17.3 4.8 0.0 2.1 5.5 1.1 4.6 1.5 0.3 5.4 3.0 0.7 0.9 2.9 1.3 1.6 0.0 4.3 0.8 1.7 1.1 5.3 3.8 0.2 5.0 12.0 0.4 0.0 0.0 27.9 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.5 0.7 0.6 0.7 1.3 1.9 1.1 1.6 1.7 0.4 1.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 21.6 0.9 0.0 0.0 3.0 0.5 0.0 14.6 0.0 0.3 0.0 1.6 0.4 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.5 8.4 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.3 0.3 0.0 10.5 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 FGF16 MF4 ENSG00000196468 "Fibroblast growth factor 16" O43320 X 77447389-77457278 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.8" "Cell type enhanced" "Detected in some" "Fibroblasts: 1.5;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 22.5" "Group enriched" "Detected in some" 6 "basal ganglia: 3.6;hippocampal formation: 2.0;olfactory bulb: 6.7" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.01e-2)" "unprognostic (5.30e-2)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.31e-1)" "unprognostic (6.57e-2)" "unprognostic (1.49e-2)" 0.6 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.3 0.1 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FGF17 FGF-13 ENSG00000158815 "Fibroblast growth factor 17" O60258 8 22042398-22048809 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7;choroid plexus: 10.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 9.3;Cone photoreceptor cells: 14.6;Excitatory neurons: 10.6;Inhibitory neurons: 13.1" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6;testis cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.1;RPMI-8226: 1.8" "Region enriched" "Detected in single" 4 "basal ganglia: 2.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" HPA052600 Uncertain "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA052600: AB_2681881" "unprognostic (3.45e-2)" "unprognostic (1.64e-2)" "unprognostic (3.03e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (3.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (7.92e-5)" "unprognostic (6.85e-2)" "unprognostic (2.58e-4)" "unprognostic (6.55e-3)" "unprognostic (7.18e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-3)" 0.5 3.9 15.1 0.0 14.9 0.1 0.4 22.0 25.7 3.0 10.6 0.4 0.0 1.1 0.1 0.2 1.5 0.2 0.5 14.3 14.2 1.4 0.4 0.7 0.0 11.9 12.2 1.5 1.2 0.8 5.1 0.1 12.2 2.7 0.0 1.1 0.7 0.1 0.0 0.5 0.4 0.3 10.9 3.6 0.5 0.7 14.2 0.4 4.8 0.0 0.0 0.6 1.3 14.4 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 14.9 22.0 25.7 14.3 14.2 11.9 12.2 12.2 10.9 14.2 14.4 0.2 0.0 0.0 2.3 0.0 0.0 0.3 0.1 0.0 9.3 0.2 0.4 1.1 0.0 0.2 0.0 14.6 0.1 0.0 0.1 0.0 0.1 1.8 0.0 0.1 0.1 0.0 0.0 10.6 0.2 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 1.7 13.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.8 1.0 0.0 0.6 0.0 2.0 2.4 0.1 0.0 1.2 0.1 0.2 0.0 0.0 0.2 1.3 0.0 0.3 0.2 0.2 0.5 0.0 0.0 0.3 0.1 0.4 0.0 0.1 FGF18 "FGF-18, ZFGF5" ENSG00000156427 "Fibroblast growth factor 18" O76093 5 171419647-171457626 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 16.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 19.8;Cardiomyocytes: 24.4;Endometrial ciliated cells: 13.0;Glandular and luminal cells: 24.9" "Group enriched" "Detected in many" 6 "endometrial cancer: 19.0;ovarian cancer: 21.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "EFO-21: 188.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 2.3" HPA018795 Uncertain "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA018795: AB_1848523" "unprognostic (3.01e-1)" "unprognostic (2.38e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-3)" "unprognostic (6.62e-3)" "unprognostic (1.50e-1)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-3)" "unprognostic (3.65e-2)" "unprognostic (3.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.37e-8)" "unprognostic (7.33e-2)" "unprognostic (2.58e-1)" "unprognostic (3.19e-1)" "unprognostic (2.76e-2)" 4.2 0.3 1.1 0.3 1.2 0.0 2.1 1.1 2.1 1.0 1.1 0.9 0.6 0.9 0.1 0.3 1.5 0.7 16.1 1.1 1.2 0.7 0.1 2.6 0.3 1.4 1.3 0.4 0.5 0.1 1.6 0.5 1.6 1.2 0.1 0.1 1.1 0.3 3.8 1.6 0.7 0.4 1.1 0.5 0.6 0.8 1.5 0.3 1.9 0.4 0.2 0.8 0.5 1.2 0.0 0.3 0.3 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.1 3.4 0.4 0.2 188.2 0.0 0.2 0.2 0.0 0.1 0.0 3.1 0.3 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.9 0.1 3.4 0.0 0.1 0.0 0.3 2.1 0.1 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 1.5 0.1 0.5 0.0 0.2 0.6 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 1.1 2.1 1.1 1.2 1.4 1.3 1.6 1.1 1.5 1.2 6.9 6.4 0.0 0.0 2.0 2.4 2.6 0.5 6.2 0.1 6.6 19.8 24.4 1.5 1.3 1.8 0.0 0.1 3.4 0.5 0.0 0.0 6.2 13.0 3.1 4.2 1.8 0.0 0.8 0.0 0.3 9.4 0.5 24.9 0.0 0.0 2.9 0.0 0.1 0.0 2.1 1.0 0.0 0.0 2.1 0.7 0.3 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.4 0.4 3.2 1.1 0.0 0.0 0.0 0.0 5.4 4.6 0.7 1.6 5.6 3.1 0.0 2.4 0.5 1.8 0.9 FGF19 ENSG00000162344 "Fibroblast growth factor 19" O95750 11 69698238-69704022 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "gallbladder: 237.1" "Group enriched" "Detected in some" 4 "Cholangiocytes: 24.3;Ductal cells: 15.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "CAPAN-2: 138.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA036082 Approved "Secreted to blood" NA NA 133000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "HPA036082: AB_10669665" "unprognostic (7.46e-3)" "unprognostic (2.43e-3)" "unprognostic (5.52e-3)" "unprognostic (1.22e-1)" "unprognostic (4.68e-3)" "unprognostic (6.45e-2)" "unprognostic (5.72e-3)" "unprognostic (2.26e-1)" "unprognostic (6.39e-3)" "unprognostic (1.66e-2)" "unprognostic (8.82e-3)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.4 0.1 0.0 237.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 138.2 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.2 0.0 0.0 0.7 1.4 0.6 24.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.1 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.0 1.3 0.0 0.0 0.0 0.3 1.8 FGF2 FGFB ENSG00000138685 "Fibroblast growth factor 2" P09038 4 122826708-122898236 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 33.7;Astrocytes: 111.0;Endometrial stromal cells: 40.6;Fibroblasts: 77.1;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 243.8;BJ hTERT+: 148.4;fHDF/TERT166: 278.2;hTERT-HME1: 147.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000125, HPA065502" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Secreted in other tissues" NA NA 92500 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear bodies" "CAB000125: , HPA065502: " "unprognostic (1.53e-2)" "unprognostic (3.12e-1)" "unprognostic (1.08e-1)" "unprognostic (7.42e-2)" "unprognostic (2.10e-1)" "unprognostic (3.33e-1)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (2.82e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (9.85e-4)" "unprognostic (3.37e-1)" "unprognostic (4.61e-3)" "unprognostic (2.36e-1)" "unprognostic (1.81e-1)" "unprognostic (4.45e-2)" "unprognostic (3.45e-3)" 24.3 2.6 14.8 5.3 16.1 0.1 9.5 12.2 14.7 8.7 14.2 14.1 1.7 14.2 4.5 4.7 8.0 7.1 5.0 12.2 18.8 4.0 2.0 8.3 1.8 18.6 20.5 12.6 1.5 4.7 3.2 6.4 15.6 7.6 4.0 3.4 3.5 8.7 1.4 1.9 3.7 12.6 16.8 1.1 6.2 1.9 18.3 1.6 2.4 4.8 1.8 14.8 6.1 13.3 4.7 14.1 7.8 30.5 18.8 31.1 0.0 243.8 148.4 104.3 60.2 0.2 0.4 0.0 20.5 278.2 81.8 0.7 8.1 0.5 104.3 12.3 3.3 0.0 28.7 0.2 55.3 1.4 0.1 16.8 1.7 103.6 147.6 52.0 11.8 0.0 6.9 8.4 27.4 0.1 0.1 0.2 21.6 0.1 5.4 0.0 3.9 0.1 33.0 0.0 4.4 4.0 48.4 0.1 2.0 44.7 0.1 0.5 10.6 85.7 12.2 32.0 20.0 8.6 10.3 0.0 24.7 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 16.1 12.2 14.7 12.2 18.8 18.6 20.5 15.6 16.8 18.3 13.3 33.7 6.4 0.0 111.0 0.3 1.7 1.6 0.8 2.8 4.6 4.5 8.9 4.7 0.0 1.3 7.3 0.0 2.7 0.4 0.0 3.9 8.2 10.9 1.5 40.6 11.5 1.8 0.4 1.8 1.0 0.1 77.1 0.0 1.6 0.0 5.7 17.2 1.3 0.5 0.0 6.6 0.0 0.0 0.0 2.4 3.8 9.9 1.7 5.4 15.9 0.6 9.3 0.0 42.3 5.8 11.0 0.0 8.2 1.6 16.0 0.0 0.6 0.0 2.0 0.0 15.2 14.2 4.7 1.1 0.3 1.3 4.8 0.5 0.1 0.0 2.0 FGF20 ENSG00000078579 "Fibroblast growth factor 20" Q9NP95 8 16992181-17002345 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5" "Cell type enriched" "Detected in some" 7 "Microglial cells: 8.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;CAPAN-2: 5.3;OE19: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Secreted in other tissues" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (5.57e-3)" "unprognostic (3.95e-2)" "unprognostic (1.59e-3)" "unprognostic (1.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.65e-2)" "unprognostic (9.32e-2)" "unprognostic (9.95e-2)" "unprognostic (3.92e-1)" "unprognostic (4.08e-2)" 0.1 0.6 0.8 0.0 0.8 0.0 0.2 2.5 1.4 0.9 0.5 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.1 0.8 1.2 0.0 0.0 0.1 0.1 1.1 1.2 0.6 0.1 0.0 0.4 0.1 1.4 0.2 0.0 0.1 1.1 0.1 0.0 0.0 0.1 0.0 1.1 1.0 0.6 0.2 1.4 0.2 0.2 0.0 0.4 0.1 0.1 1.6 0.0 0.0 0.1 0.0 0.4 0.6 0.0 0.6 1.6 0.2 0.8 0.0 5.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 2.5 1.4 0.8 1.2 1.1 1.2 1.4 1.1 1.4 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 1.0 0.0 0.0 0.0 1.2 0.0 8.4 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 FGF21 ENSG00000105550 "Fibroblast growth factor 21" Q9NSA1 19 48755524-48758333 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 106 "liver: 84.1" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 116.4" "Cancer enriched" "Detected in single" 315 "liver cancer: 33.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HHSteC: 1.4;U-2 OS: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061286 Supported "Secreted to blood" NA NA 254000 73000 "Cluster 62: Liver - Hemostasis" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA061286: AB_2684466" "unprognostic (1.64e-2)" "unprognostic (3.62e-1)" "unprognostic (3.21e-2)" "unprognostic (3.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FGF22 ENSG00000070388 "Fibroblast growth factor 22" Q9HCT0 19 639879-644371 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 13.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.4;Horizontal cells: 13.5;Muller glia cells: 4.7;Rod photoreceptor cells: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-3)" "unprognostic (1.04e-2)" "unprognostic (1.17e-1)" "unprognostic (5.25e-4)" "unprognostic (1.16e-1)" "unprognostic (3.66e-3)" "unprognostic (2.85e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-4)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (3.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.31e-1)" "unprognostic (8.36e-2)" 0.5 0.3 2.6 0.0 2.8 0.0 0.6 2.4 4.9 0.7 1.3 0.6 0.2 0.6 0.0 0.5 1.0 0.0 0.3 2.5 2.1 0.4 0.2 0.3 0.0 2.6 2.6 2.9 0.2 0.0 0.6 0.0 2.7 1.1 0.0 0.1 0.6 0.1 0.7 13.5 0.4 0.0 1.8 0.2 0.6 1.1 2.9 0.0 0.2 0.0 0.0 0.9 0.9 3.0 0.2 0.3 0.1 1.9 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.1 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.7 0.0 0.0 0.3 0.1 0.2 0.4 0.7 0.5 0.0 0.1 0.0 0.3 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.1 0.1 0.2 0.1 0.0 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.8 2.4 4.9 2.5 2.1 2.6 2.6 2.7 1.8 2.9 3.0 0.6 3.2 0.0 1.0 0.6 0.8 1.3 0.0 0.0 8.4 0.5 0.6 1.4 1.5 0.1 0.0 0.0 0.4 1.2 0.6 0.0 0.1 0.6 0.6 0.6 0.5 0.0 0.4 1.6 0.0 0.4 1.1 0.0 1.0 0.0 0.5 0.7 0.4 0.2 13.5 0.9 0.5 0.0 0.0 1.0 0.2 0.3 0.1 1.8 0.0 0.2 4.7 0.0 0.0 1.6 0.4 0.1 0.0 0.7 1.5 0.8 0.5 0.2 6.4 0.0 1.9 0.9 1.1 2.0 0.0 1.0 3.4 1.6 0.2 0.5 0.6 FGF23 ENSG00000118972 "Fibroblast growth factor 23" Q9GZV9 12 4368227-4379712 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" Differentiation "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 126.3;choroid plexus: 104.9" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 10.4;Early spermatids: 6.6;Hepatic stellate cells: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 10.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 10.8" "Cell line enhanced" "Detected in some" "AF22: 1.9;HBEC3-KT: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 56800 "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.31e-1)" "unprognostic (2.18e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" 0.2 0.1 74.8 0.1 73.5 0.5 0.2 73.8 126.3 0.0 104.9 0.2 0.3 0.3 1.2 0.2 0.3 0.1 5.0 74.1 74.1 0.2 4.1 0.2 0.2 73.8 86.6 0.2 0.1 0.1 0.0 0.2 77.8 0.1 0.6 2.3 0.5 0.0 1.2 0.3 0.1 0.3 72.9 0.5 0.2 0.5 73.3 0.1 0.1 0.3 0.6 0.1 0.0 78.6 0.0 0.0 1.9 0.6 0.9 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.7 0.1 0.0 0.3 0.1 0.4 0.2 1.4 0.0 0.0 0.2 0.0 0.3 0.2 0.5 0.4 0.1 0.5 0.0 0.9 1.1 0.1 0.1 0.0 0.1 0.8 0.0 0.0 0.2 0.5 0.5 0.1 0.0 0.3 0.0 0.3 0.2 0.4 0.4 0.3 0.0 0.6 0.1 0.3 0.4 0.3 0.0 0.7 0.1 0.5 0.1 0.0 0.0 0.1 0.4 0.1 0.4 10.8 1.4 2.0 1.6 1.5 1.9 1.8 1.5 1.2 1.2 1.9 1.7 1.7 4.8 2.2 2.5 1.9 1.6 1.1 74.8 73.5 73.8 126.3 74.1 74.1 73.8 86.6 77.8 72.9 73.3 78.6 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.9 1.5 0.0 0.0 10.4 0.1 0.3 0.0 0.0 0.0 6.6 0.0 0.2 0.5 0.0 0.0 0.8 0.0 0.1 0.4 0.0 0.1 0.0 0.0 13.6 0.0 0.2 1.7 0.3 0.0 0.0 0.6 0.3 1.8 0.3 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.2 FGF3 "HBGF-3, INT2" ENSG00000186895 "Fibroblast growth factor 3" P11487 11 69809968-69819416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "brain: 3.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.4" "Region enriched" "Detected in single" 5 "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 3.1" "Not detected" "Not detected" HPA012692 Enhanced "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA012692: AB_1848526" "unprognostic (6.42e-3)" "unprognostic (7.82e-2)" "unprognostic (1.89e-1)" "unprognostic (3.61e-1)" "unprognostic (7.75e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.1 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF4 "HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF" ENSG00000075388 "Fibroblast growth factor 4" P08620 11 69771022-69775341 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 1.1;Early spermatids: 3.1;Late spermatids: 1.4;Spermatocytes: 1.5" "Cancer enriched" "Detected in some" 5 "testis cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "NTERA-2: 16.1;SuSa: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA011209 Uncertain "Secreted in other tissues" NA NA 326000 "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA011209: AB_1848527" "unprognostic (1.47e-2)" "unprognostic (6.22e-2)" "unprognostic (7.77e-2)" "unprognostic (8.56e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF5 ENSG00000138675 "Fibroblast growth factor 5" P12034 4 80266599-80336680 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.7;gallbladder: 3.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Excitatory neurons: 9.4;Microglial cells: 1.9;Proximal tubular cells: 4.1" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 11.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.1;BJ hTERT+: 120.0;fHDF/TERT166: 88.0;HBF TERT88: 88.0;LHCN-M2: 81.1;U-138 MG: 109.5;U-251 MG: 55.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB010313, HPA042442" Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010313: AB_2102677, HPA042442: AB_2678001" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (8.49e-4)" "unprognostic (1.10e-1)" "unprognostic (2.91e-1)" "unprognostic (2.80e-3)" "unprognostic (6.87e-4)" "unprognostic (2.53e-1)" "unprognostic (1.69e-1)" "unprognostic (3.57e-3)" "unprognostic (1.17e-2)" "unprognostic (3.33e-16)" "unprognostic (3.02e-3)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" 0.0 0.0 0.2 0.6 0.0 0.1 0.0 11.7 1.2 0.0 0.0 1.4 0.1 0.1 0.0 0.1 0.0 3.4 0.1 0.6 0.0 0.8 0.0 0.0 0.0 2.7 0.2 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 1.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.1 6.1 21.8 0.0 64.1 120.0 16.5 12.2 0.0 0.1 0.0 0.0 88.0 1.2 0.1 0.1 22.5 88.0 0.0 1.1 0.2 0.1 0.0 1.7 0.6 0.0 6.3 0.0 48.6 23.0 27.9 5.7 0.0 0.0 0.2 81.1 0.0 0.1 0.3 0.1 0.0 2.1 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.8 0.0 0.0 0.2 20.9 109.5 4.6 5.4 55.0 0.0 0.0 0.1 6.3 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.7 1.2 0.6 0.0 2.7 0.2 3.0 0.0 0.5 0.5 0.0 0.0 1.1 0.3 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.6 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 FGF6 ENSG00000111241 "Fibroblast growth factor 6" P10767 12 4428155-4445614 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "skeletal muscle: 16.0;tongue: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 2.4;REH: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "unprognostic (4.29e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 2.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FGF8 AIGF ENSG00000107831 "Fibroblast growth factor 8" P55075 10 101770130-101780369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "skeletal muscle: 48.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.1;testis cancer: 3.3" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 17 "RH-30: 37.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.56e-1)" "unprognostic (3.90e-3)" "unprognostic (1.12e-2)" "unprognostic (4.88e-1)" "unprognostic (2.47e-2)" "unprognostic (9.09e-2)" "unprognostic (8.75e-3)" "unprognostic (8.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.95e-2)" "unprognostic (1.17e-2)" "unprognostic (2.35e-9)" "unprognostic (6.17e-3)" "unprognostic (9.01e-2)" "unprognostic (1.97e-1)" 0.5 0.0 0.7 0.0 0.7 0.2 0.2 0.6 1.2 0.1 0.8 0.2 0.3 0.2 0.2 0.9 0.1 0.3 0.3 0.9 1.1 0.1 0.1 0.3 0.3 0.5 0.7 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.1 0.5 0.0 0.1 48.7 0.2 0.0 0.0 0.4 0.6 0.1 1.1 0.7 0.0 0.2 0.0 0.0 0.2 0.0 1.0 0.6 0.1 0.3 1.4 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.6 0.7 0.4 0.6 0.0 0.0 0.5 0.3 0.0 0.0 1.1 1.0 0.4 0.3 0.5 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.1 0.0 1.0 0.3 0.9 0.0 0.4 0.6 2.2 0.2 0.0 0.1 0.6 37.8 0.8 0.0 0.2 0.9 0.9 0.0 0.6 0.5 0.0 0.6 0.1 0.6 0.6 1.1 0.8 0.2 0.2 0.8 1.3 0.8 0.7 0.8 1.9 0.4 0.5 0.3 0.5 0.6 0.4 0.4 0.4 0.4 0.5 0.6 0.5 1.1 0.7 0.9 0.4 0.5 0.3 0.7 0.7 0.6 1.2 0.9 1.1 0.5 0.7 0.6 0.4 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 FGF9 ENSG00000102678 "Fibroblast growth factor 9" P31371 13 21671073-21704498 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 10.7;retina: 8.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 39.2;Excitatory neurons: 36.7;Horizontal cells: 40.4;Inhibitory neurons: 54.7;Muller glia cells: 138.8" "Group enriched" "Detected in some" 5 "endometrial cancer: 3.7;ovarian cancer: 1.2;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.4;HEK 293: 1.4;JURKAT: 2.1;RPMI-8226: 2.1;RPTEC TERT1: 3.0;SCLC-21H: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067007 Enhanced Approved "Secreted in other tissues" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" "HPA067007: AB_2732755" "unprognostic (6.59e-3)" "unprognostic (9.09e-3)" "unprognostic (2.15e-2)" "unprognostic (9.24e-2)" "unprognostic (2.19e-1)" "unprognostic (2.37e-2)" "unprognostic (7.42e-4)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (3.86e-1)" "unprognostic (2.38e-3)" "unprognostic (7.93e-2)" "prognostic favorable (1.70e-6)" "unprognostic (5.38e-2)" "unprognostic (1.27e-1)" "unprognostic (3.49e-1)" "unprognostic (6.92e-2)" 2.4 4.0 1.1 0.1 1.4 0.2 0.2 5.8 4.7 1.5 0.2 0.8 0.7 1.6 0.2 0.2 0.4 0.4 2.7 1.3 1.9 10.7 0.0 0.9 0.1 3.7 1.6 1.0 0.5 0.1 2.2 0.1 4.3 0.3 1.2 8.2 0.3 0.5 0.5 0.1 1.8 0.3 1.2 0.1 0.8 0.5 3.0 0.1 0.1 0.5 0.0 1.2 0.8 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.9 0.5 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.6 2.1 3.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.4 5.8 4.7 1.3 1.9 3.7 1.6 4.3 1.2 3.0 2.1 0.9 9.6 5.6 12.1 1.8 1.7 0.2 0.6 0.0 14.4 0.7 2.7 25.7 0.0 1.3 3.7 0.0 0.1 3.2 1.7 39.2 0.4 9.4 13.1 2.6 1.6 18.6 0.0 36.7 0.0 0.0 3.9 0.0 26.6 0.0 1.2 0.0 0.0 0.1 40.4 54.7 2.7 0.0 0.0 1.6 2.9 0.6 0.5 1.8 1.9 1.6 138.8 3.1 9.5 1.7 0.2 0.5 0.0 1.9 0.1 10.9 1.1 0.0 5.9 0.0 1.0 0.7 6.3 6.2 0.1 1.4 0.3 3.2 0.1 7.5 0.1 FGFBP1 "FGFBP, HBP17" ENSG00000137440 "Fibroblast growth factor binding protein 1" Q14512 4 15935577-15938740 "Cancer-related genes, Predicted secreted proteins" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 117.1;esophagus: 421.8;vagina: 172.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1044.3;Basal respiratory cells: 596.2;Squamous epithelial cells: 528.5;Suprabasal keratinocytes: 786.2;Urothelial cells: 303.6" "Group enriched" "Detected in many" 5 "cervical cancer: 117.5;head and neck cancer: 246.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 556.3;HBEC3-KT: 968.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004332 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA004332: AB_1078856" "unprognostic (2.87e-3)" "unprognostic (3.55e-1)" "unprognostic (5.03e-2)" "unprognostic (6.99e-2)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (5.03e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-2)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (3.31e-3)" 0.6 0.1 0.0 1.7 0.0 0.1 13.5 0.0 0.0 117.1 0.0 22.1 1.8 0.5 0.1 421.8 1.2 0.3 0.2 0.0 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.1 0.4 0.0 0.2 1.1 0.0 1.7 15.6 0.0 59.7 0.1 0.1 91.2 7.0 1.1 0.0 0.1 2.0 0.0 0.0 0.3 0.7 0.0 38.4 14.9 172.3 0.0 150.7 10.5 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 189.0 0.0 10.9 0.0 0.2 556.3 0.0 968.2 0.0 0.0 1.2 0.0 2.0 0.0 0.2 0.0 0.4 0.1 141.0 0.0 17.7 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 7.9 75.2 0.0 0.0 0.0 93.4 6.7 0.0 0.0 0.2 0.0 0.2 0.0 0.9 0.5 0.1 0.2 0.3 0.0 0.3 0.0 0.1 0.2 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 8.4 0.0 0.3 1044.3 182.5 596.2 217.4 0.0 11.8 3.2 0.1 0.0 223.2 0.0 0.0 0.2 0.2 49.6 0.0 49.7 0.0 52.8 3.3 6.3 0.0 0.0 0.0 7.5 2.4 6.2 0.0 65.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.1 42.7 0.0 60.6 0.0 0.0 0.9 74.7 0.0 0.6 0.0 1.0 0.0 0.0 139.1 50.8 0.0 0.0 90.8 0.7 0.0 56.8 0.0 0.0 0.0 10.4 0.0 0.0 528.5 786.2 2.3 2.1 0.0 26.1 303.6 FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 29.0;bone marrow: 54.6" "Group enriched" "Detected in many" 6 "dendritic cells: 486.6;NK-cells: 1627.2" "Group enriched" "Detected in many" 9 "glioma: 4.8;head and neck cancer: 13.1;lung cancer: 16.7;melanoma: 16.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 551.3;memory CD8 T-cell: 332.1" "Lineage enriched" "Detected in many" 8 "T-cells: 551.3" "Cell line enhanced" "Detected in some" "SK-MEL-30: 6.9;T-47d: 3.2;WM-115: 1.3" "Secreted to blood" NA NA 346000000 36000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.51e-3)" "unprognostic (8.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (1.35e-2)" "unprognostic (9.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (3.51e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (9.61e-2)" "unprognostic (1.49e-2)" 29.0 1.5 0.9 0.4 1.0 54.6 12.7 0.8 1.5 0.6 0.8 11.8 0.1 0.5 7.2 0.6 0.7 0.9 23.6 1.0 1.1 0.5 1.2 8.5 2.9 0.9 0.8 0.4 0.2 0.3 0.2 0.5 0.9 1.4 0.9 1.1 8.6 0.9 1.1 21.0 2.0 0.3 0.8 14.0 1.7 8.6 0.9 5.3 1.1 3.6 1.0 2.8 1.8 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 6.9 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 3.5 0.8 2.4 551.3 1.3 5.2 0.8 128.6 332.1 0.9 0.4 47.3 314.1 8.4 64.9 1.6 2.1 0.9 371.2 0.9 1.0 0.8 1.5 1.0 1.1 0.9 0.8 0.9 0.8 0.9 0.9 2.6 0.0 5.3 0.0 2.6 9.6 0.0 0.2 0.0 0.0 1.5 1.7 1.5 5.7 1.4 5.5 8.4 0.6 486.6 0.1 0.0 0.7 1.3 0.9 0.1 2.2 0.0 3.6 0.0 0.0 0.0 19.9 0.5 0.3 3.8 60.3 6.1 0.6 0.0 0.0 0.0 0.4 0.0 4.9 12.0 3.0 0.0 2.2 46.2 0.0 5.8 1.4 1627.2 0.0 0.1 0.2 0.0 0.4 17.5 0.0 0.0 1.3 1.3 0.4 0.0 1.8 2.5 0.7 0.1 0.1 7.7 1.0 167.2 0.2 0.1 0.0 FGFBP3 "C10orf13, MGC39320" ENSG00000174721 "Fibroblast growth factor binding protein 3" Q8TAT2 10 91906584-91909486 "Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 19.6;Enteroendocrine cells: 46.2;Muller glia cells: 28.2" "Cancer enhanced" "Detected in many" "glioma: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 9 "AF22: 315.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA053943 Uncertain "Secreted in brain" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA053943: AB_2682318" "unprognostic (8.66e-2)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (2.88e-1)" "unprognostic (9.98e-3)" "unprognostic (7.76e-2)" "unprognostic (1.43e-1)" "unprognostic (1.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.39e-3)" "unprognostic (2.61e-1)" "unprognostic (3.90e-1)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "unprognostic (2.63e-1)" "unprognostic (6.76e-3)" 1.0 1.4 3.9 0.8 3.6 0.6 1.1 3.0 4.4 1.5 2.0 1.0 0.6 1.4 1.5 0.9 1.1 0.2 0.9 3.3 4.3 1.6 0.6 0.7 0.8 4.1 3.7 1.4 1.9 0.9 2.2 0.4 3.7 1.7 1.0 4.5 1.5 0.6 2.0 1.3 1.1 0.4 3.3 1.3 1.2 0.5 4.0 0.8 2.3 0.6 0.6 1.5 1.1 4.0 0.3 2.5 315.8 4.7 1.3 0.4 1.1 0.2 0.2 0.6 1.0 0.8 1.2 0.4 0.4 0.6 0.1 1.3 2.2 0.3 0.8 1.2 3.4 6.5 2.6 3.8 0.7 35.5 0.9 0.9 0.4 1.6 1.5 1.0 0.2 4.1 3.4 1.2 0.1 2.7 4.1 14.2 23.4 1.3 1.1 10.5 2.0 0.5 0.5 0.8 3.3 4.3 0.8 0.1 5.7 1.8 1.3 0.7 0.3 0.3 2.3 0.4 1.1 0.8 2.0 1.3 0.3 4.1 0.6 0.6 0.1 0.0 0.5 0.0 0.1 0.8 0.3 0.2 0.1 1.7 0.5 0.4 0.0 0.3 0.0 0.1 0.0 0.0 3.9 3.6 3.0 4.4 3.3 4.3 4.1 3.7 3.7 3.3 4.0 4.0 2.8 0.0 2.0 2.6 2.9 1.3 5.1 0.3 1.2 13.0 5.4 5.1 3.2 4.3 2.9 5.5 2.1 2.9 4.4 1.7 19.6 2.0 0.3 1.4 1.9 2.6 46.2 2.1 1.9 3.4 1.1 3.8 5.1 1.3 0.0 3.2 3.3 1.5 1.4 6.7 2.7 7.6 0.0 3.4 2.6 0.5 5.9 2.5 3.6 1.0 2.5 28.2 10.3 5.5 2.6 0.6 2.4 3.8 3.1 3.2 1.0 3.2 4.9 15.9 0.0 4.6 3.1 0.3 1.0 4.7 2.7 1.0 6.4 2.6 3.8 4.3 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.3;esophagus: 139.7;skin 1: 271.5" "Cell type enhanced" "Detected in many" "Astrocytes: 410.4;Basal keratinocytes: 103.8;Cholangiocytes: 91.5;Suprabasal keratinocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 48.2;HaCaT: 34.9;Hep G2: 80.6;NTERA-2: 36.1;RT4: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" NA NA 2500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.6 1.6 118.0 1.5 140.6 1.4 5.5 115.6 104.0 23.7 37.4 12.2 19.5 1.5 2.8 139.7 2.2 7.9 4.8 100.8 107.6 39.3 40.7 7.4 0.4 144.7 129.2 0.5 76.4 0.2 16.1 9.3 109.8 13.8 5.2 0.2 20.2 15.0 1.3 271.5 14.7 0.4 108.9 4.0 7.8 17.6 148.3 1.7 1.5 0.9 11.1 23.1 60.9 81.2 0.0 3.8 19.5 5.6 0.0 0.3 22.1 2.4 0.3 0.8 0.4 48.2 1.0 0.0 17.8 0.7 0.7 34.9 5.5 0.3 0.3 0.2 19.3 14.2 3.9 80.6 0.1 0.0 0.6 0.0 10.9 0.2 0.1 0.1 0.1 2.3 16.7 0.1 0.0 23.9 0.8 0.5 36.1 19.5 0.1 1.2 1.0 0.3 2.8 64.1 5.7 1.6 1.9 4.0 0.0 22.2 20.4 2.5 1.0 0.0 2.1 0.5 1.6 0.1 0.0 0.0 0.2 1.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.0 140.6 115.6 104.0 100.8 107.6 144.7 129.2 109.8 108.9 148.3 81.2 2.2 0.0 32.5 410.4 1.1 103.8 4.1 29.8 23.9 0.0 4.8 1.5 3.1 91.5 37.6 14.7 0.0 0.5 1.6 36.1 0.0 5.0 7.9 3.0 1.7 3.4 4.2 0.0 0.5 0.7 12.0 3.2 3.6 4.0 0.0 0.1 16.1 30.4 0.6 0.0 1.3 20.7 4.1 1.2 6.5 1.3 0.6 0.6 12.4 14.0 0.6 0.1 0.0 34.2 2.2 0.4 18.0 0.4 0.0 4.2 21.2 9.9 9.8 0.6 0.0 0.7 2.9 0.4 25.9 55.0 88.7 0.8 0.7 0.1 17.0 12.8 FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 330 "liver: 16556.3" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 10221.7" "Cancer enriched" "Detected in many" 19 "liver cancer: 1503.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "Hep G2: 735.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 267000000000 73000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB033120: AB_2103818, HPA027529: AB_10601322, HPA074638: " "unprognostic (1.26e-2)" "unprognostic (4.77e-3)" "unprognostic (6.33e-3)" "unprognostic (3.69e-3)" "unprognostic (2.18e-3)" "unprognostic (9.63e-2)" "unprognostic (7.57e-3)" "prognostic unfavorable (1.00e-6)" "unprognostic (1.75e-3)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" 1.7 34.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.3 0.0 0.4 0.0 0.4 0.2 0.6 0.7 25.0 1.2 0.0 0.0 8.8 16556.3 50.2 0.1 0.0 0.0 1.4 15.8 0.0 0.4 6.3 0.0 0.4 0.0 0.0 0.4 0.3 0.4 0.5 0.6 0.0 0.0 9.1 8.7 3.0 0.1 0.3 0.4 0.0 0.0 0.5 0.6 0.1 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 1.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.5 0.4 735.3 0.2 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.3 0.0 0.6 0.0 0.0 0.3 6.4 0.0 0.0 0.6 0.0 0.0 5.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.1 0.1 1.7 0.0 3.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 19.2 214.4 0.0 31.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 633.4 2.5 0.0 0.0 0.0 0.0 0.1 0.0 21.9 4.3 0.0 0.1 9.2 0.0 157.7 0.0 48.5 0.2 0.5 0.0 0.1 11.4 1.1 202.4 10221.7 0.2 0.0 0.0 0.0 0.0 289.5 0.0 0.5 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 161.8 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.0 0.4 17.3 0.2 0.0 0.0 FGL1 "HFREP-1, HPS" ENSG00000104760 "Fibrinogen like 1" Q08830 8 17864380-17910365 "Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 4163.9" "Cell type enriched" "Detected in many" 27 "Hepatocytes: 8261.7" "Cancer enriched" "Detected in some" 40 "liver cancer: 399.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "A549: 55.4;Hep G2: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 57000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (3.62e-2)" "unprognostic (1.14e-2)" "unprognostic (1.75e-5)" "unprognostic (3.00e-1)" "unprognostic (3.54e-2)" "unprognostic (7.89e-2)" "unprognostic (2.15e-1)" "unprognostic (2.62e-1)" "unprognostic (2.71e-1)" "unprognostic (1.09e-2)" "unprognostic (2.86e-7)" "prognostic unfavorable (5.38e-4)" "unprognostic (3.62e-1)" "unprognostic (2.58e-2)" "unprognostic (1.35e-1)" 0.9 0.4 1.2 0.0 1.4 0.0 1.0 1.0 1.8 0.4 0.9 0.2 0.0 0.7 0.7 0.2 0.2 0.1 0.3 1.3 1.7 0.5 4163.9 1.2 0.0 1.3 1.6 0.3 660.1 0.0 0.2 6.3 1.3 3.8 0.1 0.2 0.2 0.0 0.1 0.1 0.3 0.2 1.1 3.8 0.6 4.3 1.5 0.0 0.3 0.0 0.0 0.1 0.1 1.2 0.0 55.4 0.0 6.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 131.9 0.0 1.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 1.3 0.8 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 1.0 1.8 1.3 1.7 1.3 1.6 1.3 1.1 1.5 1.2 0.0 0.0 1.9 12.4 24.6 0.0 0.2 0.0 0.0 0.0 1.3 0.9 2.1 301.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 8.3 42.9 5.4 1.0 7.6 0.0 176.4 0.1 71.2 0.4 0.1 0.0 7.8 0.0 0.0 173.8 8261.7 20.4 0.0 0.3 0.0 0.0 231.6 0.0 32.7 0.6 0.2 0.0 14.0 1.6 0.0 0.0 2.5 0.0 74.1 0.0 0.4 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.7 0.0 0.0 1.0 12.8 0.1 0.3 0.2 FGL2 "pT49, T49" ENSG00000127951 "Fibrinogen like 2" Q14314 7 77193369-77199848 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 162.5" "Group enriched" "Detected in many" 4 "Kupffer cells: 466.3;Langerhans cells: 571.0;Macrophages: 430.3;monocytes: 463.1;Skeletal myocytes: 166.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 45 "classical monocyte: 256.5;eosinophil: 226.3;intermediate monocyte: 380.6;myeloid DC: 160.0;neutrophil: 294.7;non-classical monocyte: 379.8" "Group enriched" "Detected in all" 59 "dendritic cells: 160.0;granulocytes: 294.7;monocytes: 380.6" "Cell line enhanced" "Detected in some" "Karpas-707: 2.0;LHCN-M2: 2.9;NB-4: 2.9;RPTEC TERT1: 5.0;THP-1: 2.1;U-937: 5.0;WM-115: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021011, HPA026682" Enhanced "Secreted to blood" NA NA 38800000 7800000 "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "HPA021011: AB_1848532, HPA026682: AB_1848533" "unprognostic (9.80e-3)" "unprognostic (4.70e-3)" "unprognostic (1.19e-1)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-2)" "unprognostic (3.49e-1)" "unprognostic (2.70e-1)" "unprognostic (3.19e-1)" "unprognostic (1.27e-1)" "unprognostic (1.19e-1)" "unprognostic (5.00e-2)" "unprognostic (1.91e-2)" "unprognostic (2.33e-1)" "unprognostic (7.01e-2)" 48.5 24.4 3.3 89.4 2.7 5.8 35.1 5.3 3.5 17.2 6.1 44.9 43.7 17.8 7.6 38.5 22.1 45.4 21.6 2.4 5.4 44.9 43.5 32.7 56.5 7.7 5.9 10.9 8.3 5.2 7.9 21.6 6.7 10.5 57.2 0.8 14.8 11.7 8.8 13.9 69.8 45.7 6.2 162.5 23.5 6.2 3.9 30.1 18.8 24.6 27.5 73.3 7.1 9.8 0.0 0.0 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.9 0.0 0.0 2.9 0.1 0.0 0.0 0.1 0.2 0.3 5.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.0 5.7 2.8 256.5 226.3 3.9 380.6 1.2 4.3 2.5 3.4 160.0 2.0 1.8 3.0 294.7 2.5 379.8 6.2 4.7 174.0 3.3 2.7 5.3 3.5 2.4 5.4 7.7 5.9 6.7 6.2 3.9 9.8 102.0 6.4 12.1 0.0 26.2 38.1 1.1 0.1 3.4 1.1 1.4 3.0 4.4 0.0 5.0 88.3 10.4 1.3 60.3 17.3 5.9 1.9 7.5 2.6 0.7 50.6 0.0 7.0 0.3 0.0 1.4 102.8 2.0 5.0 10.1 0.6 45.3 5.2 36.2 1.7 0.4 0.3 0.0 466.3 571.0 9.4 27.7 430.3 49.8 33.7 463.1 13.6 39.1 0.0 0.9 0.1 10.9 19.5 82.6 1.1 42.5 5.9 2.2 7.4 0.0 166.2 8.2 0.4 0.4 2.1 31.3 3.7 24.1 0.2 0.8 1.5 FKRP "FKTR, LGMD2I, MDC1C" ENSG00000181027 "Fukutin related protein" Q9H9S5 19 46746046-46776988 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transferase "Cardiomyopathy, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043115, HPA060454" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA043115: AB_2678324, HPA060454: AB_2684281" "unprognostic (4.44e-2)" "unprognostic (5.20e-2)" "unprognostic (2.19e-2)" "unprognostic (8.37e-3)" "unprognostic (1.83e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "unprognostic (2.99e-2)" "unprognostic (4.59e-3)" "prognostic favorable (8.98e-4)" "unprognostic (3.53e-1)" "unprognostic (2.30e-2)" "unprognostic (2.53e-1)" "unprognostic (2.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.53e-2)" 10.5 9.1 8.5 8.1 8.2 8.8 9.9 3.7 11.5 11.4 4.5 13.3 4.8 15.2 5.0 8.8 12.6 6.0 15.8 8.5 10.4 12.0 11.9 10.4 7.4 10.1 7.3 12.7 11.1 7.5 16.8 10.1 8.8 13.5 4.3 5.7 11.1 7.4 19.6 7.2 10.5 5.8 6.1 14.7 10.9 9.3 9.4 5.6 13.6 9.8 4.9 13.0 10.5 8.7 12.7 26.5 17.8 12.5 15.4 16.9 15.8 31.7 21.0 12.6 19.9 17.0 21.4 11.7 17.0 18.2 20.9 13.0 6.6 14.8 11.5 21.9 22.2 11.7 14.4 10.7 13.3 9.3 19.8 19.4 12.5 15.6 15.2 14.6 16.7 6.0 12.2 11.0 12.7 5.8 6.8 22.8 17.2 7.8 6.5 18.3 11.1 4.0 8.0 26.4 12.0 23.1 15.8 7.6 10.6 11.7 8.9 7.3 16.8 18.4 19.8 6.7 25.7 11.6 15.4 11.0 15.0 7.5 25.6 1.3 1.8 0.8 1.5 1.0 0.9 1.7 1.1 1.7 1.1 2.4 1.2 1.6 2.2 2.0 1.1 1.9 0.6 1.2 8.5 8.2 3.7 11.5 8.5 10.4 10.1 7.3 8.8 6.1 9.4 8.7 4.7 9.6 7.4 6.8 3.9 0.8 4.8 3.0 1.2 9.8 5.3 5.2 15.5 4.3 5.6 5.5 6.2 9.6 9.1 4.5 5.9 4.2 12.0 7.9 7.3 6.0 7.8 7.8 6.8 2.4 5.9 6.6 3.6 5.1 1.3 6.7 11.4 16.6 7.6 3.3 8.2 4.2 2.0 10.0 1.2 13.2 5.6 4.3 5.4 3.7 6.1 7.8 2.1 8.0 6.2 4.1 4.7 4.1 3.6 4.3 4.2 8.2 9.7 11.0 6.6 7.2 7.0 12.2 4.0 2.4 1.6 18.7 4.3 4.5 4.0 4.3 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FLT3LG ENSG00000090554 "Fms related receptor tyrosine kinase 3 ligand" P49771 19 49474207-49486231 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 22.6;T-cells: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 77.8;MAIT T-cell: 144.4;memory CD4 T-cell: 158.2;memory CD8 T-cell: 102.0;naive CD4 T-cell: 169.7;naive CD8 T-cell: 137.8;T-reg: 171.1" "Lineage enriched" "Detected in all" 6 "T-cells: 171.1" "Cell line enhanced" "Detected in many" "HDLM-2: 26.1;U-266/70: 25.0" "Low region specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.29e-3)" "prognostic favorable (2.17e-5)" "unprognostic (2.12e-3)" "unprognostic (9.16e-2)" "unprognostic (3.05e-1)" "unprognostic (3.81e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (1.16e-2)" "unprognostic (2.88e-1)" "unprognostic (7.78e-6)" "unprognostic (2.17e-1)" "unprognostic (5.25e-2)" "unprognostic (8.22e-3)" "unprognostic (5.68e-2)" 21.4 9.5 7.0 18.7 7.1 16.5 17.8 6.1 7.8 27.0 7.1 21.5 9.4 18.2 3.6 11.3 18.0 7.2 11.1 6.2 6.7 12.5 8.0 14.9 24.1 8.7 6.8 18.6 4.7 2.7 8.6 3.5 7.5 20.6 3.3 1.9 10.1 7.0 7.9 13.9 18.2 5.0 6.5 21.0 11.9 3.2 7.4 22.0 13.1 4.5 10.5 18.9 24.4 7.7 6.1 0.5 0.8 2.2 9.8 16.2 0.6 4.5 9.6 9.7 16.2 0.4 6.3 6.1 2.4 6.8 3.0 6.5 1.6 5.0 2.4 26.1 2.5 4.2 3.3 2.5 16.9 4.0 14.6 11.2 0.7 7.1 1.3 6.4 3.3 8.2 1.9 19.4 2.9 5.0 4.0 6.5 0.2 1.0 1.2 3.2 3.2 6.9 1.4 3.8 0.5 2.0 1.4 1.8 2.8 0.2 2.6 3.2 2.4 12.0 2.4 7.0 6.5 25.0 8.2 2.6 5.7 8.1 3.4 5.8 7.6 24.0 77.8 21.7 144.4 14.1 158.2 102.0 6.2 11.5 169.7 137.8 7.7 29.8 29.5 2.6 171.1 46.2 7.0 7.1 6.1 7.8 6.2 6.7 8.7 6.8 7.5 6.5 7.4 7.7 10.6 0.0 3.7 3.9 10.5 5.1 6.1 5.7 16.5 1.7 4.3 5.8 0.4 1.5 6.5 3.7 6.2 0.6 17.9 0.4 0.0 1.9 0.4 0.9 5.6 7.9 1.8 2.5 0.5 1.8 0.8 15.5 10.2 0.8 5.7 2.6 8.6 1.4 1.9 8.4 0.7 1.3 0.0 5.1 9.4 0.2 16.4 5.8 8.8 3.7 6.4 5.1 22.6 1.5 1.4 1.5 4.1 7.9 6.5 2.9 0.4 3.7 1.4 2.2 6.6 5.8 9.1 0.8 3.1 7.3 4.7 0.3 73.6 1.5 0.8 5.3 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.7;Fibroblasts: 52.5;Intestinal goblet cells: 80.2;Leydig cells: 28.0;Peritubular cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.6;CACO-2: 38.6;HHSteC: 11.8;HSkMC: 22.1;OE19: 45.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 71.7" "Secreted to extracellular matrix" NA NA 2600000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (9.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.17e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-1)" "unprognostic (5.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (9.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (2.67e-4)" 122.7 13.6 1.3 31.1 2.3 0.1 64.4 1.5 3.9 100.1 9.0 39.4 49.6 105.8 17.2 19.1 85.8 123.6 149.0 1.0 1.5 24.3 11.0 60.2 28.6 2.4 0.9 125.1 33.1 28.0 21.7 81.2 1.5 58.4 62.1 9.9 49.6 49.2 12.6 25.9 21.2 106.5 2.1 18.2 135.6 6.3 1.5 9.6 71.3 25.6 33.8 45.4 60.0 1.4 0.0 0.1 0.0 0.0 10.6 0.7 0.2 7.1 8.1 0.0 1.1 38.6 0.0 0.0 0.8 7.7 0.0 0.3 0.0 0.6 0.5 0.0 0.0 0.0 0.9 0.0 11.8 0.0 0.0 22.1 0.1 0.0 0.4 5.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.3 0.0 45.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 1.0 0.3 2.0 0.0 0.3 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.3 1.5 3.9 1.0 1.5 2.4 0.9 1.5 2.1 1.5 1.4 9.3 0.0 6.3 0.0 0.0 6.9 5.0 1.5 6.2 0.2 10.3 26.7 1.6 2.8 2.1 7.3 0.0 1.1 0.4 2.9 0.0 1.9 0.1 1.1 12.1 8.3 6.1 0.0 0.1 0.7 0.7 52.5 12.8 1.6 0.0 0.5 19.2 0.1 1.2 0.0 0.0 80.2 0.0 0.3 9.3 0.4 28.0 0.6 12.4 7.5 0.6 11.9 0.0 0.0 0.0 1.5 2.2 28.6 0.0 11.7 0.7 0.2 0.7 1.0 6.6 1.3 15.5 0.0 0.3 0.6 4.3 3.1 1.2 2.0 8.6 1.6 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 14.2;thyroid gland: 20.3" "Group enriched" "Detected in some" 4 "Fibroblasts: 28.7;Smooth muscle cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 5.4;hippocampal formation: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;fHDF/TERT166: 2.9;SuSa: 3.1" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" NA NA 14000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" 5.4 0.5 0.5 1.9 0.3 0.0 2.1 0.1 5.4 6.5 0.2 12.9 2.5 2.2 0.0 1.1 0.6 14.2 3.9 8.7 0.3 0.6 0.7 1.6 2.8 0.1 1.0 1.2 1.1 0.3 0.2 0.9 0.0 0.4 1.8 0.1 0.9 0.8 2.1 0.9 4.2 11.7 0.3 0.5 0.4 0.4 0.4 0.1 20.3 9.6 2.4 1.0 1.6 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 5.4 8.7 0.3 0.1 1.0 0.0 0.3 0.4 1.2 2.6 0.0 0.6 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.1 0.5 2.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.3 0.4 4.7 0.7 0.0 0.0 0.2 0.0 0.2 28.7 0.0 0.3 0.0 0.1 1.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 3.1 0.0 0.3 0.2 1.8 2.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 3.0 11.5 1.1 1.4 0.0 1.4 0.1 0.5 0.1 0.0 0.0 FNDC7 FLJ35838 ENSG00000143107 "Fibronectin type III domain containing 7" Q5VTL7 1 108712908-108742749 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;testis: 1.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 4.6;Late spermatids: 1.5;Oligodendrocyte precursor cells: 3.5;Oligodendrocytes: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028079, HPA054297" Enhanced Approved "Nucleoplasm,Actin filaments" "Secreted in male reproductive system" NA NA "Cluster 77: Retina - Visual perception" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Actin filaments" Nucleoplasm "HPA028079: AB_10602501, HPA054297: AB_2682441" "unprognostic (2.35e-2)" "unprognostic (2.65e-2)" "unprognostic (3.74e-1)" "unprognostic (8.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-4)" "unprognostic (1.90e-10)" "unprognostic (1.59e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" 0.0 0.0 0.4 0.0 0.4 0.1 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.8 0.4 1.1 1.3 0.6 0.7 0.4 0.5 0.2 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.6 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.8 0.0 3.5 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 FOLR1 "FOLR, FRα" ENSG00000110195 "Folate receptor alpha" P15328 11 72189558-72196323 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Transport Receptor Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 480.2;fallopian tube: 187.2;lung: 193.5;salivary gland: 219.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 496.8;Alveolar cells type 2: 213.3;Breast glandular cells: 211.3;Club cells: 276.3;Collecting duct cells: 318.2;Cytotrophoblasts: 462.2;Proximal tubular cells: 366.0;Syncytiotrophoblasts: 259.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 259.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HeLa: 444.2;RPTEC TERT1: 476.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077030 Approved "Nuclear membrane" "Secreted to blood" NA NA 448000 140000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear membrane" "HPA077030: " "unprognostic (3.30e-1)" "unprognostic (2.19e-1)" "unprognostic (6.55e-2)" "unprognostic (3.49e-2)" "unprognostic (7.67e-3)" "unprognostic (1.98e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.18e-2)" "unprognostic (8.13e-2)" "unprognostic (2.47e-2)" "unprognostic (2.58e-2)" "unprognostic (2.87e-3)" "unprognostic (1.67e-1)" "unprognostic (2.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.20e-1)" "unprognostic (2.69e-1)" 0.1 1.7 2.7 0.2 1.8 0.1 28.3 11.8 1.8 123.5 480.2 0.5 0.3 1.9 7.6 3.4 187.2 2.4 0.6 14.1 4.1 153.0 0.2 193.5 0.0 5.7 7.8 0.7 7.1 17.5 8.1 36.2 3.8 1.5 0.4 0.5 219.5 15.2 0.1 2.5 0.4 0.2 3.2 0.2 33.0 0.2 7.7 0.2 45.9 0.0 0.4 0.1 0.1 2.7 0.2 0.2 0.0 0.2 0.0 0.0 64.7 0.1 0.1 0.1 0.1 44.5 46.0 0.0 45.5 0.8 0.0 0.9 2.4 2.1 0.2 0.1 1.4 1.0 444.2 1.3 0.0 0.0 0.1 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.5 0.1 0.1 2.2 0.7 0.0 0.5 15.1 0.0 476.5 0.0 0.1 3.0 1.4 7.1 0.1 38.5 65.7 0.5 0.0 0.0 8.4 0.3 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1.8 11.8 1.8 14.1 4.1 5.7 7.8 3.8 3.2 7.7 2.7 1.0 496.8 213.3 0.0 1.3 0.9 7.9 80.3 0.0 0.0 211.3 62.9 0.2 34.3 276.3 318.2 0.0 462.2 1.1 0.0 133.1 14.3 0.1 33.6 2.3 3.4 1.8 0.0 0.0 1.4 110.9 4.3 9.7 33.7 5.1 0.0 0.0 0.0 29.5 0.0 0.0 0.1 87.5 0.0 0.4 0.0 0.6 3.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.3 0.0 366.0 149.1 0.1 0.0 0.1 6.3 0.0 0.5 3.2 0.1 259.0 2.2 0.3 0.3 10.4 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FOLR3 "FR-G, FRγ" ENSG00000110203 "Folate receptor gamma" P41439 11 72114869-72139892 "Metabolic proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 98.7;lymphoid tissue: 28.4" "Group enriched" "Detected in some" 10 "Distal tubular cells: 406.9;monocytes: 103.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 5.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "classical monocyte: 330.8;neutrophil: 492.8" "Group enriched" "Detected in many" 11 "granulocytes: 492.8;monocytes: 330.8" "Group enriched" "Detected in some" 5 "hTERT-HME1: 72.4;U-2197: 64.7" "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.47e-2)" "unprognostic (6.26e-3)" "unprognostic (1.94e-2)" "unprognostic (8.72e-3)" "unprognostic (6.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "unprognostic (3.72e-1)" "unprognostic (1.72e-1)" "unprognostic (1.54e-1)" "unprognostic (7.35e-2)" "unprognostic (7.90e-2)" "unprognostic (8.39e-2)" "unprognostic (9.99e-4)" "unprognostic (1.96e-1)" "unprognostic (2.03e-6)" "unprognostic (4.17e-1)" 5.7 0.4 0.3 10.6 0.2 98.7 0.2 0.2 0.5 0.2 0.3 0.2 0.4 0.0 0.0 1.0 0.9 0.3 0.5 0.2 0.3 8.6 0.8 5.9 0.1 0.3 0.3 0.0 0.2 0.0 0.1 0.7 0.3 0.2 0.1 0.0 0.6 0.1 0.1 0.6 0.5 0.6 0.2 28.4 0.4 0.9 0.6 1.3 1.7 0.5 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.3 10.4 13.1 3.7 9.2 0.0 0.0 0.0 1.3 2.0 0.2 1.1 0.0 6.9 8.4 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 8.8 5.4 72.4 1.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.6 0.3 64.7 0.0 0.1 0.0 0.0 2.7 0.0 0.0 15.1 330.8 30.9 0.5 26.1 1.8 0.3 0.1 0.2 36.2 0.1 0.1 0.0 492.8 0.5 1.4 6.3 0.4 294.4 0.3 0.2 0.2 0.5 0.2 0.3 0.3 0.3 0.3 0.2 0.6 0.3 0.1 0.0 7.9 0.0 1.1 0.3 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 1.9 23.9 0.0 0.1 1.3 0.0 406.9 0.1 3.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 3.8 0.0 1.1 0.0 1.6 0.0 0.0 0.0 0.0 22.4 1.7 10.9 0.0 17.4 0.0 0.0 103.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 18.1 1.5 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 1.0 0.1 0.0 0.1 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FREM3 ENSG00000183090 "FRAS1 related extracellular matrix 3" P0C091 4 143577302-143700675 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.3" "Cell type enhanced" "Detected in some" "Astrocytes: 1.6;Excitatory neurons: 9.7;Inhibitory neurons: 3.6;Oligodendrocyte precursor cells: 4.5;Oligodendrocytes: 2.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 3.1;hypothalamus: 2.8;thalamus: 4.4" HPA041641 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA041641: AB_2677592" "unprognostic (1.19e-2)" "unprognostic (4.09e-9)" "unprognostic (3.09e-3)" "unprognostic (2.74e-1)" "unprognostic (1.66e-1)" "unprognostic (4.74e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-1)" "unprognostic (2.68e-1)" "unprognostic (2.17e-1)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" "unprognostic (7.11e-3)" "unprognostic (3.24e-1)" 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 1.3 0.6 0.0 0.0 0.2 0.2 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.2 0.6 0.3 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 1.0 0.0 0.0 0.0 4.5 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.2;ASC diff: 9.4;NTERA-2: 7.4;SH-SY5Y: 6.5" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" 10.4 5.7 10.4 6.1 12.8 0.7 12.6 11.0 18.6 20.3 52.2 16.2 14.4 17.2 11.4 12.4 7.1 39.0 19.9 10.3 11.2 16.3 3.3 9.1 18.7 14.1 10.9 13.5 7.1 6.7 18.6 30.5 15.4 12.9 19.9 336.9 4.7 16.6 26.6 10.4 14.5 31.1 11.9 88.9 21.9 14.2 11.3 4.9 10.8 116.2 11.9 10.3 12.3 10.3 0.0 0.0 19.2 0.2 9.4 0.2 0.2 0.0 0.9 3.2 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 7.4 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.0 6.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 12.8 11.0 18.6 10.3 11.2 14.1 10.9 15.4 11.9 11.3 10.3 13.8 0.0 0.5 1.0 0.8 8.2 0.4 0.2 0.6 39.8 7.8 18.7 2.9 0.0 1.4 0.0 33.3 5.3 0.5 2.1 0.0 0.1 0.3 0.5 1.4 18.5 1.2 0.0 2.7 8.2 3.8 97.8 9.7 0.9 0.0 0.5 3.6 1.0 7.8 26.9 7.7 137.4 0.0 0.8 3.7 2.8 3.7 0.5 245.5 25.3 0.0 3633.8 0.0 8.5 1.7 0.2 0.8 14.7 5.8 1.8 1.3 0.2 0.2 124.4 276.1 41.9 157.1 0.2 0.1 0.6 3.1 12.4 1.5 22.9 3.4 0.6 FSHB ENSG00000131808 "Follicle stimulating hormone subunit beta" P01225 11 30231014-30235261 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 436 "pituitary gland: 239.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB023410, HPA069703" Enhanced "Secreted to blood" NA NA 78000 "Cluster 26: Pituitary gland - Hormone signaling" "CAB023410: AB_324983, HPA069703: AB_2686176" "unprognostic (1.04e-1)" 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 239.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.7" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 700.1" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 351.1;HaCaT: 292.3;HBEC3-KT: 191.3;HMC-1: 206.5;PC-3: 558.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" 26.1 6.2 0.8 3.0 0.5 0.4 15.2 0.4 0.7 7.7 0.7 9.8 1.8 4.2 3.7 6.5 11.8 7.2 9.4 2.0 2.0 2.9 68.7 8.2 1.6 1.8 1.0 9.9 2.6 0.5 5.9 24.1 0.9 15.5 3.0 0.3 11.3 10.8 9.2 18.0 8.8 4.7 0.5 0.3 11.1 5.0 1.1 2.3 4.0 7.7 12.9 40.4 7.5 0.7 20.0 1.8 33.7 0.0 38.6 13.5 55.4 76.3 351.1 46.4 45.4 0.3 0.2 0.0 0.6 19.9 2.3 292.3 0.0 191.3 32.7 0.8 0.2 4.0 1.7 31.3 20.4 0.3 206.5 31.0 0.5 84.5 55.0 31.3 40.0 0.0 0.0 0.6 29.7 0.1 0.1 1.6 52.1 0.0 558.2 4.2 43.6 0.0 0.0 31.9 0.5 0.1 3.1 0.2 2.0 83.9 0.3 0.3 0.2 124.1 35.3 13.2 11.1 0.4 0.1 0.1 14.8 4.1 116.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.4 0.7 2.0 2.0 1.8 1.0 0.9 0.5 1.1 0.7 5.2 0.0 1.1 0.0 1.0 20.0 31.5 64.4 13.1 0.0 0.9 23.4 11.4 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.4 0.1 3.4 2.9 0.0 0.0 0.1 4.6 14.8 107.7 3.6 0.1 0.0 700.1 1.1 57.2 1.8 0.0 0.7 0.0 2.0 0.8 16.4 1.5 3.1 1.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 11.3 0.2 37.1 0.0 0.1 1.6 0.0 13.1 29.6 33.3 0.3 12.2 4.0 4.7 6.0 2.0 0.3 0.0 51.8 FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.1;Fibroblasts: 521.9;Leydig cells: 327.4;Peritubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 1782.4;BJ: 2156.3;fHDF/TERT166: 2692.9;HBF TERT88: 1741.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" 432.4 134.3 20.5 116.3 18.1 2.2 166.1 22.8 22.7 279.9 83.0 156.4 37.1 157.5 50.8 126.1 150.6 257.0 242.7 20.6 22.8 45.4 35.7 120.7 50.3 28.5 44.6 90.3 37.3 35.5 25.7 442.0 23.1 188.3 90.4 29.8 59.3 184.4 31.8 64.2 69.1 409.6 22.7 63.1 68.6 33.5 22.7 24.2 78.8 89.8 38.8 260.4 104.3 20.6 81.0 21.2 222.9 91.8 1304.4 1782.4 1.3 2156.3 1208.9 1374.5 1211.0 0.1 178.5 0.8 178.8 2692.9 112.8 20.5 68.6 270.0 1741.5 1.1 32.5 0.4 159.8 0.3 286.0 1.2 0.9 1362.7 8.5 884.5 192.7 612.1 811.6 11.2 0.5 0.3 227.6 0.5 22.6 2.0 181.3 0.4 181.9 0.7 92.7 1.0 150.4 1.7 39.2 93.5 764.6 13.6 76.5 462.6 23.5 6.2 986.8 507.4 479.8 268.0 323.8 1.0 1.1 2.3 177.4 0.9 67.0 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 2.6 20.5 18.1 22.8 22.7 20.6 22.8 28.5 44.6 23.1 22.7 22.7 20.6 76.9 64.1 9.4 56.5 1.1 64.1 31.9 36.4 10.2 2.3 25.6 24.6 127.5 8.6 42.5 23.9 0.0 114.4 2.5 0.9 0.0 62.6 2.3 44.4 176.7 111.4 3.0 3.6 9.6 5.8 352.1 521.9 3.1 23.0 1.3 66.5 142.5 17.4 20.6 1.7 16.2 0.2 8.2 10.8 91.6 9.8 327.4 11.5 110.3 30.0 9.9 116.1 0.0 9.5 0.9 117.8 0.7 270.8 0.9 108.4 0.0 5.5 74.9 4.3 59.2 62.5 129.3 1.5 4.4 2.2 48.2 54.7 7.1 47.5 0.9 65.3 FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 3647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 164.7;hTCEpi: 181.2;SiHa: 341.5;U-2197: 173.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" 82.9 163.3 16.6 24.1 15.3 13.3 62.4 13.3 19.8 75.6 16.0 82.7 7.7 62.0 6.1 22.0 70.2 16.5 124.1 16.4 17.3 55.9 26.2 132.7 5.5 22.6 16.0 63.8 49.3 3.2 28.9 179.4 17.9 74.9 5.9 2.4 21.1 22.1 11.7 32.3 36.5 42.4 16.7 22.6 43.2 75.2 18.1 2.3 37.9 4.9 1.6 70.5 63.1 18.9 9.5 74.0 5.1 3.7 22.3 56.4 164.7 126.1 18.5 30.7 11.3 27.1 14.4 4.1 49.4 84.7 17.6 65.2 4.1 106.4 10.1 7.8 8.7 3.5 110.2 22.4 95.6 6.7 12.0 70.7 181.2 34.0 140.2 79.3 5.5 3.9 8.2 5.3 46.7 33.1 2.4 4.0 6.2 62.0 26.2 7.2 3.4 8.7 43.1 1.7 3.3 5.7 341.5 6.9 4.3 6.4 6.2 3.5 75.5 30.6 106.6 173.4 46.9 8.5 4.4 2.3 4.7 20.0 14.2 0.0 1.9 0.0 0.4 1.8 0.0 0.1 0.6 0.4 0.9 0.3 1.0 0.6 0.0 0.2 1.4 0.3 0.0 0.9 16.6 15.3 13.3 19.8 16.4 17.3 22.6 16.0 17.9 16.7 18.1 18.9 4.6 19.2 1.9 40.5 1.5 14.5 31.0 11.7 1.8 1.3 11.3 7.9 16.7 32.9 4.4 9.2 0.0 53.9 1.0 1.1 7.9 86.1 8.8 6.4 14.8 8.7 1.2 1.7 9.8 64.3 3647.6 59.6 2.0 18.3 0.0 5.7 16.4 1.9 77.1 3.3 8.4 1.0 0.0 3.7 4.8 7.6 61.2 7.4 5.4 2.8 10.6 6.6 1.0 6.0 5.5 306.5 0.2 26.7 1.0 78.0 1.2 17.7 3.1 1.1 46.0 22.4 57.0 4.6 5.6 4.3 7.7 792.0 2.0 3.6 2.5 30.7 FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 390.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SCLC-21H: 57.2;U-266/70: 19.3;U-266/84: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045920 Uncertain Uncertain Mitochondria "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA045920: AB_10965844" "unprognostic (5.52e-2)" "unprognostic (2.54e-1)" "unprognostic (5.74e-2)" "unprognostic (8.14e-2)" "unprognostic (1.87e-1)" "unprognostic (3.97e-2)" "unprognostic (6.35e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (4.74e-2)" "unprognostic (8.66e-2)" "unprognostic (3.73e-4)" "unprognostic (2.02e-2)" "unprognostic (9.91e-3)" "unprognostic (1.03e-2)" "unprognostic (4.25e-2)" 0.1 1.3 5.5 0.6 5.5 1.9 0.6 8.5 11.2 0.3 0.0 1.1 0.7 0.2 1.5 1.9 0.9 0.5 0.3 3.1 3.2 2.8 0.1 1.2 0.3 0.0 6.2 0.4 1.9 3.1 2.3 3.8 0.0 1.6 1.1 3.9 0.7 0.0 0.9 3.4 0.8 0.2 0.0 0.4 1.4 1.7 21.4 1.3 0.8 0.5 1.1 6.0 0.9 7.8 7.5 13.1 1.4 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 12.5 1.7 0.7 10.5 0.0 1.3 0.2 1.7 0.5 0.0 0.9 0.6 0.6 13.9 1.1 0.0 0.0 0.7 0.3 1.8 0.0 0.1 0.3 0.0 0.5 5.9 7.0 0.0 12.7 1.5 0.6 14.4 14.2 1.6 0.6 1.3 14.1 0.0 15.0 57.2 1.6 2.9 2.4 0.3 12.2 4.6 0.5 0.3 0.6 2.4 0.8 0.4 19.3 20.7 0.5 0.2 0.1 0.4 1.1 0.2 0.1 0.2 0.0 0.5 0.6 0.4 0.3 0.1 0.5 0.4 0.2 0.5 0.2 0.2 0.3 0.3 0.3 5.5 5.5 8.5 11.2 3.1 3.2 0.0 6.2 0.0 0.0 21.4 7.8 0.0 0.0 3.1 21.5 1.0 1.7 2.5 0.2 4.0 10.1 0.6 0.3 9.6 0.0 4.4 0.0 14.6 0.4 0.1 0.0 0.0 0.2 35.9 1.2 0.2 0.6 9.0 0.0 390.3 0.0 0.0 0.4 0.0 0.1 0.0 1.4 0.0 0.0 0.1 1.7 57.9 0.4 0.0 0.0 0.0 20.4 0.3 1.2 10.6 8.4 0.0 3.0 0.0 21.1 4.5 0.6 0.0 0.7 0.0 0.4 0.2 2.5 3.7 2.6 6.6 0.0 1.1 0.5 0.7 3.3 1.6 0.0 0.4 0.9 0.1 2.9 FSTL5 "DKFZp566D234, KIAA1263" ENSG00000168843 "Follistatin like 5" Q8N475 4 161383897-162164004 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 68.6;retina: 94.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 306.0;Cone photoreceptor cells: 462.9;Excitatory neurons: 184.7;Inhibitory neurons: 517.7;Rod photoreceptor cells: 139.6" "Cancer enriched" "Detected in single" 6 "melanoma: 1.7" "Region enriched" "Detected in all" 5 "cerebellum: 68.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 75.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 57.3" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.90e-2)" "unprognostic (4.46e-1)" "unprognostic (1.52e-2)" "unprognostic (2.03e-1)" "unprognostic (3.66e-2)" "unprognostic (2.99e-2)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (1.10e-1)" "unprognostic (3.39e-2)" "unprognostic (1.61e-1)" "unprognostic (1.08e-10)" "unprognostic (8.45e-4)" "unprognostic (1.53e-1)" "unprognostic (1.52e-1)" "unprognostic (6.60e-3)" 0.0 6.0 7.4 0.0 6.9 0.0 0.0 68.6 3.7 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.1 15.2 0.0 0.0 0.0 0.0 12.7 9.9 0.0 0.3 0.0 1.2 0.1 14.4 0.0 0.1 94.8 0.0 0.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.6 9.6 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.1 0.0 0.9 0.0 0.0 0.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 75.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 10.8 0.0 0.0 0.7 0.1 0.0 0.3 0.1 0.0 0.0 16.2 0.0 6.2 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 6.9 68.6 3.7 3.1 15.2 12.7 9.9 14.4 6.2 9.6 5.1 0.0 0.0 0.0 47.7 0.0 0.3 0.0 0.0 0.0 306.0 0.0 0.0 0.1 0.0 0.0 0.0 462.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.8 0.0 0.0 184.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 28.6 517.7 0.0 0.0 0.3 0.3 4.5 0.6 0.0 1.8 7.5 0.0 20.7 0.0 8.0 75.3 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.0 139.6 0.0 0.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Excitatory neurons: 43.5;Oligodendrocytes: 115.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065748 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA065748: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" 2.4 4.9 4.4 0.9 7.9 2.3 2.1 5.4 5.5 0.6 1.8 1.1 1.0 0.4 1.8 1.3 1.9 0.9 2.9 4.5 4.8 4.2 10.0 1.4 2.0 6.1 6.7 1.0 2.2 1.5 0.9 0.6 5.7 1.2 1.1 1.4 2.4 0.6 8.1 1.2 0.8 1.1 6.1 4.6 0.9 1.0 6.0 0.7 5.7 8.4 0.8 0.7 0.9 7.6 0.6 1.9 0.1 0.0 1.9 1.1 1.4 0.7 0.7 1.0 0.4 0.0 3.5 2.0 0.2 0.8 5.7 0.0 0.9 5.3 1.2 2.3 0.5 1.5 0.8 1.7 0.7 5.5 6.5 0.8 0.2 0.4 0.1 0.7 0.0 4.9 2.7 0.1 0.7 6.0 1.9 2.1 1.6 0.5 4.0 0.3 0.2 0.0 0.4 0.0 2.3 0.0 3.4 3.2 3.2 1.3 4.8 7.1 0.6 2.7 0.0 1.8 1.1 4.7 2.9 1.1 5.2 2.7 1.3 0.0 4.1 1.7 0.4 5.5 1.7 3.4 1.7 0.6 5.8 2.1 1.1 1.8 0.0 1.1 5.1 8.7 0.0 1.4 4.4 7.9 5.4 5.5 4.5 4.8 6.1 6.7 5.7 6.1 6.0 7.6 0.8 0.0 0.0 39.8 3.2 2.7 2.9 0.0 13.6 3.3 6.2 5.5 5.7 4.3 1.3 3.7 4.2 1.5 3.3 0.3 1.9 0.2 2.4 8.4 0.8 1.5 0.0 5.9 43.5 0.7 1.4 1.4 4.6 3.3 0.0 5.9 2.2 6.9 7.4 1.7 23.5 1.2 0.0 8.1 4.7 1.0 0.3 8.2 7.2 17.8 2.1 1.7 0.0 24.6 115.4 0.3 0.1 0.4 1.4 2.6 1.0 10.6 0.0 6.5 0.0 2.4 3.4 0.4 2.0 6.9 2.3 0.3 1.5 10.3 1.1 1.2 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494812-143511720 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 165.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" NA NA 56000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 28.9 41.4 13.5 25.4 16.4 25.8 26.3 16.0 15.3 29.2 30.2 41.5 42.6 25.6 44.9 14.2 23.7 27.8 27.9 12.4 16.5 54.8 52.3 28.9 17.2 17.1 14.2 30.4 34.6 165.8 15.8 50.5 17.8 21.9 52.8 6.1 25.4 25.8 6.9 12.3 39.3 27.6 16.4 24.6 38.3 12.6 15.9 6.6 32.0 11.6 17.0 33.5 20.4 20.9 97.4 55.7 47.6 86.9 69.0 134.4 90.1 89.9 95.4 108.1 182.0 107.1 94.8 0.2 66.1 120.8 33.9 0.6 24.1 11.7 148.9 87.2 92.6 32.6 100.1 163.2 99.3 0.3 15.8 72.3 69.4 96.6 41.5 91.6 111.4 0.2 117.6 49.3 123.2 114.6 0.2 75.9 62.1 44.2 76.0 0.2 99.7 72.1 129.0 59.5 36.0 23.6 98.7 65.3 82.3 36.3 32.1 79.6 65.9 64.1 54.0 161.6 175.4 18.3 21.3 0.7 74.1 59.1 22.5 38.8 84.9 26.2 13.2 84.0 15.0 11.3 9.8 11.3 65.4 8.3 4.4 7.9 5.5 29.6 62.0 10.3 19.8 51.9 13.5 16.4 16.0 15.3 12.4 16.5 17.1 14.2 17.8 16.4 15.9 20.9 27.3 41.7 35.9 9.1 13.5 11.2 12.6 30.3 9.1 3.7 19.2 12.6 28.0 38.6 37.9 25.8 0.0 52.5 10.3 47.6 11.7 81.9 2.0 26.8 55.2 25.0 9.6 18.7 8.7 124.9 109.8 62.6 34.7 28.9 37.4 38.1 23.6 35.2 110.3 1.7 11.8 38.1 46.8 57.5 29.2 2.6 66.8 51.7 42.7 9.4 49.1 11.1 13.4 5.5 14.5 74.6 38.2 45.5 47.7 13.8 60.3 51.4 34.8 1.1 6.6 33.8 35.0 4.8 4.6 13.2 8.0 46.4 11.5 78.8 50.4 18.4 FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.4;kidney: 36.1;salivary gland: 45.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 35.6;Intestinal goblet cells: 39.4;Paneth cells: 21.5;Proximal enterocytes: 101.4;Proximal tubular cells: 45.3;Undifferentiated cells: 29.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 6 "Hep G2: 10.5;RPMI-8226: 4.0" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 51000 "Cluster 10: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA043707: AB_2678628, HPA046966: AB_2679879" "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favorable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" 0.1 0.0 0.1 2.6 0.1 0.4 1.7 0.2 0.1 17.3 0.4 17.3 28.6 0.3 0.0 79.4 0.6 9.3 0.0 0.1 0.1 36.1 12.4 0.2 0.1 0.1 0.1 0.0 3.7 0.0 0.0 0.0 0.1 0.2 11.6 2.0 45.7 2.5 0.0 0.1 27.0 0.4 0.1 0.1 4.8 0.2 0.1 0.0 0.0 0.0 6.7 0.0 26.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.2 10.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.7 4.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.5 0.0 0.7 0.0 0.4 3.5 0.0 0.4 3.7 1.9 0.3 18.6 15.7 1.8 0.0 0.2 0.3 35.6 3.9 6.8 0.3 0.6 0.7 0.3 4.9 0.0 0.1 0.4 0.1 0.3 0.0 0.7 0.0 0.2 0.7 5.1 0.1 0.0 0.1 39.4 8.2 0.0 0.8 0.0 0.3 0.4 0.0 0.0 0.0 0.9 0.0 0.5 0.1 2.7 21.5 0.0 0.0 0.2 101.4 45.3 6.4 11.5 0.0 0.3 0.7 1.0 0.6 3.6 0.1 0.0 0.5 0.1 29.0 1.7 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "brain: 645.9;pituitary gland: 885.8" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 22.2;Ductal cells: 38.9;Endometrial ciliated cells: 64.2;Endometrial stromal cells: 50.8;Exocrine glandular cells: 52.1;Extravillous trophoblasts: 48.7;Glandular and luminal cells: 26.4;Pancreatic endocrine cells: 39.5;Prostatic glandular cells: 82.5;Urothelial cells: 24.3" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in many" 13 "hypothalamus: 645.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 267.2;HEK 293: 119.3;K-562: 139.5;NB-4: 493.5;SH-SY5Y: 189.6" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 60000 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 24: NB-4 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 3.2 0.9 2.8 14.9 2.1 0.7 4.4 1.1 5.2 1.0 0.8 17.6 1.8 0.2 0.0 0.8 1.0 0.2 1.0 2.2 645.9 1.5 0.3 0.5 0.1 48.5 5.1 0.2 2.1 0.1 885.8 0.3 13.8 4.4 4.0 0.0 0.9 0.2 0.4 33.3 4.1 9.9 0.6 0.3 9.7 1.0 19.5 0.7 0.4 0.0 0.0 0.7 2.9 2.6 0.0 11.0 1.1 0.3 0.0 0.0 24.0 36.7 0.0 0.7 0.0 267.2 9.9 0.0 12.7 1.3 0.4 0.1 0.0 0.2 0.0 0.0 119.3 6.4 74.6 0.0 1.3 3.7 0.0 1.7 4.0 0.0 0.1 0.0 6.3 0.0 139.5 0.0 0.2 77.2 0.0 493.5 60.3 2.9 23.7 0.0 0.1 51.1 0.6 0.0 49.8 189.6 25.8 1.5 0.0 26.8 1.5 57.6 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.1 1.1 5.2 2.2 645.9 48.5 5.1 13.8 0.6 19.5 2.6 0.6 0.0 0.0 0.0 0.2 2.0 22.2 0.1 0.0 0.0 3.2 5.8 1.4 0.0 0.0 0.0 0.0 0.6 0.1 0.7 0.0 38.9 0.1 64.2 50.8 3.4 1.8 4.2 2.1 52.1 48.7 6.6 2.0 26.4 4.5 0.4 0.0 0.0 2.0 0.0 0.2 1.1 4.1 0.0 1.2 0.2 0.0 0.7 1.8 0.0 0.6 0.0 0.0 0.0 0.3 39.5 0.1 0.0 1.0 82.5 0.0 0.4 0.0 0.0 0.0 1.6 6.7 2.2 10.9 1.1 3.4 1.9 0.8 0.0 1.3 24.3 GALP ENSG00000197487 "Galanin like peptide" Q9UBC7 19 56176008-56185775 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Hormone, Neuropeptide" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 1.8;Glandular and luminal cells: 1.0" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053938 Uncertain "Secreted in brain" NA NA "Cluster 49: Ciliated cells - Cilium organization" "HPA053938: AB_2682315" "unprognostic (8.51e-3)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (7.02e-2)" 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 348.3;Sertoli cells: 322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.7" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.7" "Cell line enhanced" "Detected in many" "BJ: 347.0;BJ hTERT+: 494.0;HSkMC: 281.3;RPMI-8226: 493.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" NA NA 8900000 3600000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Centriolar satellite" "HPA008275: AB_1849497, HPA056080: AB_2683032" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-3)" "unprognostic (1.37e-1)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (4.81e-3)" "unprognostic (1.97e-1)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "prognostic unfavorable (8.93e-6)" 124.2 32.5 26.7 18.8 28.7 3.6 77.4 33.9 32.0 244.4 59.3 67.8 48.7 171.7 13.8 63.2 161.3 58.9 169.1 24.1 34.6 72.7 37.1 97.3 22.5 37.4 36.1 118.0 49.9 58.5 58.4 51.6 38.5 100.9 25.2 6.3 84.4 63.8 99.2 101.4 47.8 57.9 30.8 29.4 70.0 60.1 34.1 39.6 101.2 67.5 10.6 127.0 172.0 25.2 151.3 6.6 4.4 3.8 169.5 94.0 18.4 347.0 494.0 141.3 168.4 9.6 71.0 1.4 11.4 157.2 24.9 139.1 2.4 77.7 35.6 0.2 20.1 1.1 11.1 1.0 120.8 1.0 2.1 281.3 44.9 39.1 39.0 243.2 5.3 2.3 2.6 79.9 231.9 7.4 0.8 1.5 9.5 24.0 9.9 4.5 0.1 493.5 51.9 1.9 23.5 21.3 38.3 1.3 0.4 23.8 45.9 119.4 81.7 36.9 45.0 4.4 100.5 0.1 8.0 1.5 41.9 3.6 5.8 0.0 1.4 0.0 0.0 1.1 0.0 0.1 0.2 0.0 11.3 0.1 0.0 0.0 0.0 0.1 0.3 70.7 0.0 1.4 26.7 28.7 33.9 32.0 24.1 34.6 37.4 36.1 38.5 30.8 34.1 25.2 133.2 198.7 25.9 23.2 20.8 84.4 94.7 18.5 70.0 38.0 17.9 114.3 86.8 50.1 23.4 31.3 0.0 1.8 59.1 92.4 27.4 45.7 5.1 35.2 33.1 71.9 10.3 5.3 26.2 6.7 1.9 152.7 19.9 32.3 8.2 154.7 159.9 21.6 101.6 348.3 31.9 69.5 8.2 22.3 100.4 8.9 92.2 48.6 122.7 41.2 9.8 32.7 0.0 3.0 7.5 24.1 58.6 59.5 147.4 30.5 84.1 0.6 15.5 12.5 322.1 22.9 121.1 5.3 17.6 27.6 71.9 2.9 4.7 214.8 151.4 31.1 GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.4;Extravillous trophoblasts: 2.6;Fibroblasts: 1.8;Hofbauer cells: 3.9;Syncytiotrophoblasts: 2.7" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;RPMI-8226: 3.4;SK-BR-3: 2.6;T-47d: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" 5.5 2.1 4.9 2.5 6.4 0.0 4.2 6.3 3.8 10.6 4.9 3.4 0.7 9.8 2.2 1.8 11.3 5.3 1.7 4.1 5.9 1.0 13.1 3.1 0.7 8.8 7.7 6.8 2.0 0.1 3.0 2.0 7.6 2.6 1.0 3.9 2.6 2.2 1.4 1.7 2.1 6.0 6.3 0.9 3.4 2.9 10.0 0.6 2.1 0.8 0.3 3.2 3.9 5.2 0.0 0.0 0.0 3.1 0.1 0.0 1.1 0.2 0.3 0.0 0.0 0.1 0.9 0.0 1.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.6 0.4 1.2 0.8 0.0 0.4 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 0.0 3.4 0.0 0.5 0.1 0.3 0.0 2.6 0.0 0.1 6.7 0.9 0.0 0.4 0.6 1.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 6.4 6.3 3.8 4.1 5.9 8.8 7.7 7.6 6.3 10.0 5.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 GAST GAS ENSG00000184502 Gastrin P01350 17 41712331-41715969 "Cancer-related genes, FDA approved drug targets, Predicted secreted proteins" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "stomach 1: 9556.1" "Cell type enriched" "Detected in some" 5 "Glandular and luminal cells: 103.7" "Group enriched" "Detected in many" 6 "pancreatic cancer: 38.8;stomach cancer: 23.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 34.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" CAB000038 Enhanced "Secreted to digestive system" NA NA 87000 "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "CAB000038: " "unprognostic (1.27e-1)" "unprognostic (4.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.75e-2)" "unprognostic (5.68e-2)" "unprognostic (2.11e-1)" "unprognostic (2.85e-1)" "unprognostic (3.17e-1)" "unprognostic (9.07e-2)" 0.0 0.0 0.9 0.0 0.6 0.0 0.7 0.4 0.9 0.2 0.4 0.0 57.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.3 0.0 3.7 0.0 0.8 1.0 0.0 0.0 0.0 0.1 4.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 9.3 9556.1 0.3 2.5 4.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 5.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.8 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.4 0.9 0.5 2.5 0.8 1.0 1.0 0.6 2.5 0.6 0.8 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.3 0.9 0.4 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.1 2.2 13.5 18.7 0.7 0.0 0.0 0.0 0.0 0.1 1.0 0.5 103.7 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.8 0.2 0.2 0.0 0.0 8.8 1.0 0.0 0.0 0.4 GATD1 "FLJ34283, PDDC1" ENSG00000177225 "Glutamine amidotransferase like class 1 domain containing 1" Q8NB37 11 767220-777488 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Alveolar cells type 2: 22.1;Collecting duct cells: 22.0;Theca cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 120.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008812 Uncertain Supported Nucleoplasm "Secreted to blood" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA008812: AB_10962724" "unprognostic (3.39e-1)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (3.50e-2)" "unprognostic (2.19e-1)" "unprognostic (5.67e-2)" "unprognostic (5.23e-3)" "unprognostic (4.89e-3)" "prognostic favorable (3.79e-5)" "unprognostic (2.84e-2)" "unprognostic (8.40e-2)" "unprognostic (6.11e-2)" "unprognostic (6.61e-3)" 15.9 37.5 37.7 11.3 35.8 7.9 16.7 35.1 37.8 22.7 36.6 23.3 15.4 24.9 12.6 23.7 22.7 7.3 16.3 37.4 36.5 24.0 19.3 15.4 11.2 46.4 41.8 25.9 15.9 10.5 30.1 9.2 35.8 23.0 6.5 9.7 17.5 12.2 14.4 21.0 18.2 7.9 38.4 19.6 17.8 18.6 45.3 8.8 22.0 6.5 6.8 19.7 20.4 37.5 41.3 22.3 22.2 23.9 10.2 15.6 20.9 24.2 10.5 22.0 19.3 15.8 62.5 22.1 8.6 16.0 23.2 42.7 16.7 21.6 11.0 28.1 120.5 13.0 38.8 36.0 17.5 25.4 27.8 22.4 23.2 9.3 14.2 19.9 17.1 25.8 34.2 20.0 12.4 11.0 29.3 27.5 21.3 13.4 42.8 31.4 15.1 28.0 19.2 9.1 56.9 22.3 22.9 32.0 16.6 5.7 28.5 16.8 31.3 23.2 17.5 12.7 18.8 23.4 12.9 28.4 35.4 33.9 19.6 1.0 5.2 0.9 2.9 6.6 2.1 2.7 3.0 2.9 6.9 2.3 2.4 1.7 0.5 1.2 2.6 4.0 1.4 2.0 37.7 35.8 35.1 37.8 37.4 36.5 46.4 41.8 35.8 38.4 45.3 37.5 8.7 44.8 22.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 11.9 10.4 0.0 0.0 7.4 22.0 0.0 13.8 5.2 0.0 5.9 10.3 0.0 11.8 15.2 3.8 0.0 0.0 0.0 7.6 7.9 8.5 0.0 9.6 6.3 19.2 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 16.6 0.0 0.0 1.3 0.0 0.0 14.7 7.3 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 9.6 3.9 25.8 0.0 0.0 GC "DBP, hDBP, VDBP" ENSG00000145321 "GC vitamin D binding protein" P02774 4 71741696-71804041 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" Transport Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 8260.1" "Group enriched" "Detected in some" 27 "Cholangiocytes: 1552.8;Hepatocytes: 3017.1" "Cancer enriched" "Detected in many" 18 "liver cancer: 1016.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 2.0;RH-30: 3.0;SiHa: 1.8;U-698: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001526, CAB008596, HPA019855" Supported "Secreted to blood" NA NA 143000000000 73000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "CAB008596: AB_1622398, HPA001526: AB_1078959, HPA019855: AB_1849545" "prognostic favorable (8.08e-4)" "unprognostic (1.06e-3)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.55e-1)" "unprognostic (2.15e-1)" 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 60.3 0.0 0.6 0.1 0.0 495.5 0.1 0.0 0.0 46.1 8260.1 0.0 0.2 0.1 0.1 0.0 44.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.0 0.0 0.0 1.8 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.4 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.3 0.0 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 7.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 1552.8 0.0 0.0 0.0 0.0 0.0 0.0 5.9 39.5 0.5 0.1 0.0 2.0 0.0 37.5 0.1 16.2 0.2 0.0 0.0 0.0 0.0 0.0 58.5 3017.1 0.1 0.0 0.1 0.7 0.0 83.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 GCG "GLP-1, GLP1, GLP2, GRPP" ENSG00000115263 Glucagon P01275 2 162142882-162152404 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 1943.6" "Cell type enriched" "Detected in some" 23 "Enteroendocrine cells: 5457.0" "Cancer enriched" "Detected in some" 209 "pancreatic cancer: 428.4" "Region enriched" "Detected in single" 55 "medulla oblongata: 6.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 133.4;U-2 OS: 186.8;U-698: 44.5" "Region enriched" "Detected in single" 10 "pons and medulla: 3.5" "Region enriched" "Detected in some" 5 "spinal cord: 13.7" "CAB000040, HPA036760, HPA036761" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 127000 420000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Endoplasmic reticulum" Vesicles "CAB000040: AB_10013726, HPA036760: AB_2675296, HPA036761: AB_2675297" "unprognostic (3.13e-3)" "unprognostic (9.99e-2)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" 20.3 0.1 0.0 3.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 84.4 3.4 0.6 0.0 5.3 0.0 4.1 2.5 0.0 0.0 41.9 0.0 0.2 3.5 6.2 0.0 0.1 1943.6 0.0 0.0 0.1 0.1 0.8 151.9 0.0 0.3 0.0 0.0 37.2 130.2 0.8 0.0 0.2 41.2 0.0 0.0 0.4 0.6 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 186.8 0.2 12.1 0.0 5.6 44.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.2 0.0 0.0 0.3 0.1 5457.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 230.9 8.5 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 22.9 0.0 GDF1 ENSG00000130283 "Growth differentiation factor 1" P27539 19 18868545-18896158 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.7;pituitary gland: 1.5;skeletal muscle: 3.9;testis: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.8;SH-SY5Y: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 38: EFO-21 - Unknown function" 0.0 0.1 1.5 0.0 2.1 0.0 0.1 1.4 3.6 0.3 0.5 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.6 1.7 1.1 0.0 0.0 0.0 0.0 3.0 2.0 0.4 0.1 0.0 1.5 0.0 2.3 0.2 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 1.9 0.0 0.2 4.9 3.7 0.0 0.1 0.0 0.0 0.3 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.1 1.4 3.6 1.7 1.1 3.0 2.0 2.3 1.9 3.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GDF11 "BMP-11, BMP11" ENSG00000135414 "Growth differentiation factor 11" O95390 12 55743122-55757264 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 76.6;Cone photoreceptor cells: 77.2;Horizontal cells: 57.2;Rod photoreceptor cells: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 127.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060985, HPA069609" Approved Approved Vesicles "Secreted to blood" No No 46400 340000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA060985: AB_2684403, HPA069609: AB_2686159" "unprognostic (5.21e-2)" "unprognostic (1.62e-1)" "unprognostic (3.20e-2)" "unprognostic (2.41e-2)" "unprognostic (2.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (8.96e-3)" "unprognostic (1.23e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.69e-1)" "unprognostic (1.62e-2)" "unprognostic (1.27e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" "unprognostic (9.48e-2)" 3.6 4.0 22.5 3.7 17.5 1.8 2.3 16.4 17.8 6.8 15.9 5.4 1.6 7.6 2.0 2.4 5.0 4.6 7.5 18.1 18.5 3.0 1.3 3.6 2.8 22.0 26.6 5.7 2.9 2.9 4.7 2.0 20.9 6.0 1.6 21.6 4.8 9.4 1.8 1.5 3.7 4.6 18.3 5.6 2.7 1.1 22.3 4.6 3.6 2.0 1.8 5.9 3.4 17.7 4.9 7.6 32.8 18.6 24.4 17.8 8.2 10.1 9.5 12.5 10.7 26.0 2.1 9.5 13.0 10.5 5.9 4.6 25.0 18.0 4.3 18.2 22.7 11.7 12.3 4.1 4.9 9.8 127.7 17.2 1.0 18.3 5.2 14.0 16.4 12.7 13.2 30.1 16.0 9.2 16.0 8.5 26.4 0.3 18.9 25.1 8.9 5.9 7.7 6.6 22.2 13.6 6.2 2.8 2.6 13.3 10.7 10.7 10.1 15.0 22.9 11.9 7.4 8.1 2.6 4.9 8.0 9.7 10.8 0.2 0.2 0.5 1.2 0.1 1.0 0.7 0.7 0.7 0.2 0.7 0.6 0.8 0.3 0.2 0.4 0.7 0.5 0.1 22.5 17.5 16.4 17.8 18.1 18.5 22.0 26.6 20.9 18.3 22.3 17.7 8.4 0.0 1.1 19.2 10.9 0.5 9.8 0.6 4.0 76.6 6.3 6.6 25.6 1.5 0.9 0.0 77.2 3.6 16.6 1.5 0.0 5.0 0.6 9.9 35.2 8.0 10.7 11.1 4.3 1.4 5.3 13.3 3.1 18.0 5.7 7.6 6.4 0.2 1.6 57.2 10.8 1.9 0.0 1.9 0.7 0.8 9.0 4.4 3.6 1.9 4.1 30.6 22.6 17.1 3.2 3.3 4.1 5.7 4.1 9.8 3.4 0.5 0.1 53.1 13.1 31.1 18.1 2.9 4.1 3.0 0.9 4.7 18.9 7.2 2.2 6.2 GDF15 "MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB" ENSG00000130513 "Growth differentiation factor 15" Q99988 19 18374731-18389176 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 371.8;urinary bladder: 175.4" "Cell type enhanced" "Detected in many" "Club cells: 1160.8;Syncytiotrophoblasts: 4304.7;Urothelial cells: 3294.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Group enriched" "Detected in many" 5 "granulocytes: 2.7;monocytes: 1.2" "Cell line enhanced" "Detected in many" "BEWO: 416.5;Hep G2: 225.5;HHSteC: 564.9;TIME: 213.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011191, CAB062554, HPA070957" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 1260000 960000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "CAB062554: AB_2665632, HPA011191: AB_1078962, HPA070957: AB_2732168" "unprognostic (1.04e-1)" "unprognostic (1.89e-2)" "unprognostic (3.45e-2)" "unprognostic (3.36e-2)" "unprognostic (2.04e-2)" "unprognostic (2.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.30e-2)" "unprognostic (2.80e-1)" "unprognostic (2.89e-1)" "unprognostic (5.09e-2)" "unprognostic (1.46e-1)" "unprognostic (6.55e-3)" "unprognostic (3.81e-2)" "unprognostic (8.45e-2)" "unprognostic (1.25e-1)" "unprognostic (3.04e-3)" 34.8 11.7 1.3 1.5 1.4 0.4 24.9 1.0 2.3 18.9 40.9 29.2 4.5 13.6 2.2 4.8 5.5 19.9 4.5 4.3 1.3 371.8 88.6 46.9 0.6 2.0 1.7 4.7 112.3 25.9 12.3 86.9 1.5 105.3 24.4 1.2 12.5 4.6 5.5 6.4 12.3 1.9 1.2 11.4 75.5 1.6 2.5 0.3 11.2 0.5 1.7 175.4 19.2 1.6 1.8 95.6 9.4 3.5 22.3 18.5 416.5 33.1 17.9 1.2 18.8 4.2 29.6 0.4 58.8 3.0 97.0 0.7 0.0 12.2 4.7 0.2 2.2 0.9 9.2 225.5 564.9 0.1 35.7 48.8 140.1 90.7 58.6 0.7 99.5 0.0 152.4 0.7 22.9 23.5 0.1 0.8 5.4 34.4 52.5 0.2 3.7 0.2 69.9 94.6 0.9 1.0 0.4 5.5 127.9 35.1 2.6 0.4 213.1 0.0 7.4 1.8 1.5 1.5 4.0 0.4 51.9 0.1 27.8 0.0 0.7 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.7 0.0 1.2 0.0 0.0 0.1 1.3 1.4 1.0 2.3 4.3 1.3 2.0 1.7 1.5 1.2 2.5 1.6 6.6 35.3 62.4 0.0 1.8 1.3 350.6 366.1 0.0 0.1 54.2 15.5 0.7 47.1 1160.8 259.3 0.0 60.6 0.4 176.0 33.2 316.9 0.0 166.8 35.4 31.9 84.8 0.0 0.1 381.9 263.4 52.9 224.8 261.8 29.2 0.2 2.5 7.0 33.8 0.0 0.1 357.6 453.7 1.6 3.7 0.0 0.9 14.1 3.6 0.0 9.9 0.5 1.0 0.0 0.0 440.4 146.6 1.5 1.3 780.2 22.9 85.7 681.4 0.6 0.0 9.5 46.7 0.7 0.5 1.3 1.7 4304.7 5.5 3.4 291.0 3294.2 GDF2 "BMP-9, BMP9" ENSG00000263761 "Growth differentiation factor 2" Q9UK05 10 47322454-47327588 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "liver: 18.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB023357 Uncertain "Secreted to blood" NA NA 2210000 740000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 43: Cardiomyocytes - Nuclear processes" "CAB023357: AB_2111086" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF3 ENSG00000184344 "Growth differentiation factor 3" Q9NR23 12 7689784-7695775 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "kidney: 2.9" "Cell type enriched" "Detected in some" 25 "Granulosa cells: 30.2" "Cancer enriched" "Detected in some" 422 "testis cancer: 383.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "NTERA-2: 452.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA018468 Uncertain "Secreted to blood" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "HPA018468: AB_1849586" "unprognostic (9.48e-2)" "unprognostic (3.90e-2)" "unprognostic (3.30e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-1)" "unprognostic (5.40e-2)" "unprognostic (3.09e-1)" "unprognostic (2.08e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (1.25e-3)" "unprognostic (8.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 2.9 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.9 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.1 0.0 452.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 77.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GDF5 "BMP14, CDMP1" ENSG00000125965 "Growth differentiation factor 5" P43026 20 35433347-35454746 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Chondrogenesis "Cytokine, Growth factor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "salivary gland: 9.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.2;Basal prostatic cells: 1.0;granulocytes: 1.3" "Cancer enriched" "Detected in single" 7 "endometrial cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 17.6;BJ hTERT+: 5.4;GAMG: 9.4;HHSteC: 5.8;HSkMC: 14.4;U-87 MG: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA015648 Uncertain "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "HPA015648: AB_1849589" "unprognostic (4.59e-3)" "unprognostic (3.48e-2)" "unprognostic (5.53e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (4.64e-1)" "unprognostic (2.17e-3)" "unprognostic (4.38e-2)" "unprognostic (1.40e-1)" "unprognostic (8.02e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-3)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (1.38e-1)" "unprognostic (8.96e-3)" 0.9 0.1 0.1 0.0 0.4 0.0 0.6 0.1 0.3 0.3 0.3 1.6 0.0 0.4 0.1 0.0 0.1 0.2 0.4 0.1 0.2 0.3 0.0 2.3 0.0 0.2 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.9 0.1 0.0 9.9 1.2 0.1 0.1 0.1 0.6 0.1 0.0 0.1 0.6 0.4 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.3 17.6 0.1 2.8 5.4 0.4 1.0 0.0 0.0 0.0 0.0 4.5 9.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.8 0.0 0.0 14.4 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.4 0.2 0.1 0.0 2.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.8;seminal vesicle: 22.4" "Group enriched" "Detected in some" 12 "Endometrial stromal cells: 137.0;Granulosa cells: 83.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 4.4;RT4: 8.3;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" 0.4 0.4 0.2 1.0 0.5 0.2 0.1 0.0 2.5 9.8 0.0 0.5 0.2 7.2 3.3 0.9 0.7 0.6 0.8 0.4 0.1 3.6 5.0 0.4 2.3 0.3 0.1 0.3 0.6 0.1 0.3 0.8 0.0 3.8 0.2 0.1 0.1 22.4 0.0 1.3 1.6 1.1 0.0 1.3 0.7 0.2 0.3 0.2 0.2 0.6 1.8 1.1 6.6 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 1.2 8.3 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.5 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.6 0.1 6.4 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.5 0.0 0.0 8.8 2.8 3.1 5.5 0.0 0.0 0.1 0.1 1.9 0.1 0.1 3.5 137.0 1.8 0.0 2.7 0.2 0.0 0.1 1.3 0.0 2.9 0.0 83.7 0.0 8.2 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 4.1 0.7 0.0 0.0 0.3 7.1 0.5 1.0 0.0 0.0 0.0 0.8 0.0 0.0 1.5 GDF9 ENSG00000164404 "Growth differentiation factor 9" O60383 5 132861181-132866884 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.9" "Cell type enhanced" "Detected in some" "Early spermatids: 19.9;Late spermatids: 5.2;Spermatocytes: 15.2" "Cancer enriched" "Detected in some" 5 "breast cancer: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069146 Supported Approved "Golgi apparatus,Cytosol" "Secreted in female reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Cytosol "HPA069146: AB_2686094" "unprognostic (4.64e-1)" "unprognostic (1.22e-1)" "unprognostic (1.25e-2)" "unprognostic (5.11e-2)" "unprognostic (1.58e-2)" "unprognostic (2.39e-2)" "unprognostic (1.55e-1)" "unprognostic (4.61e-2)" "unprognostic (4.88e-2)" "unprognostic (1.68e-1)" "unprognostic (6.70e-3)" "unprognostic (1.04e-1)" "unprognostic (1.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (4.75e-3)" "unprognostic (3.10e-2)" 0.3 0.6 1.3 0.2 1.5 0.3 0.8 1.3 2.0 0.4 0.9 0.3 0.4 0.3 4.1 0.3 0.8 0.2 0.3 1.3 1.4 1.4 0.6 0.3 0.5 1.2 1.4 0.5 1.0 0.7 1.7 0.2 1.4 0.6 0.3 1.3 0.8 0.5 0.7 1.0 0.4 0.2 1.4 0.4 1.0 8.9 1.3 0.7 1.0 0.7 0.4 0.6 0.3 1.4 0.2 0.1 0.5 1.1 0.7 0.3 0.1 0.0 0.1 0.1 0.1 0.3 0.8 0.2 0.6 0.1 0.9 0.2 0.4 0.4 0.1 0.4 0.7 0.5 0.5 0.1 0.1 0.1 0.0 0.3 0.6 0.0 0.3 0.1 0.0 3.9 0.0 1.2 0.2 0.2 0.7 0.8 0.2 0.1 0.0 0.6 0.0 0.2 0.3 0.2 1.0 0.9 0.2 0.1 0.5 0.7 0.5 0.1 0.1 0.9 0.4 0.2 0.1 1.3 1.7 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.3 2.0 1.3 1.4 1.2 1.4 1.4 1.4 1.3 1.4 0.9 0.0 0.0 1.6 0.1 0.1 0.4 0.1 0.0 0.4 1.9 2.2 0.6 0.0 0.1 0.0 4.2 0.4 0.3 0.7 3.9 0.1 19.9 1.4 0.9 0.5 0.0 0.0 0.5 0.2 0.3 0.4 0.0 1.9 0.0 0.5 0.4 0.2 0.1 0.0 0.8 0.9 0.0 0.3 0.0 5.2 0.6 0.5 0.0 0.0 0.0 1.0 0.0 2.0 0.9 0.1 0.1 0.4 0.1 0.6 0.3 0.4 0.6 1.0 0.0 1.6 0.8 15.2 2.5 1.1 0.1 0.7 0.2 0.2 0.5 0.2 GDNF "ATF1, ATF2, HFB1-GDNF" ENSG00000168621 "Glial cell derived neurotrophic factor" P39905 5 37812677-37840041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes, Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8.2;skeletal muscle: 10.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 3.3;Skeletal myocytes: 11.5;Spermatogonia: 3.4;Theca cells: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 41.4;SuSa: 12.6;U-87 MG: 12.6;WM-115: 46.5" "Region enhanced" "Detected in single" "basal ganglia: 2.8" "Low region specificity" "Detected in some" "CAB005210, HPA070283" Supported Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Vesicles Nucleoplasm "CAB005210: AB_2247684, HPA070283: AB_2686246" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (3.54e-2)" "unprognostic (8.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (5.33e-2)" "unprognostic (1.92e-1)" "unprognostic (3.71e-2)" "unprognostic (2.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.10e-1)" "unprognostic (1.16e-4)" "unprognostic (2.04e-1)" "unprognostic (8.86e-2)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" 0.1 0.4 2.3 1.6 1.5 0.1 0.3 5.8 1.4 0.8 0.0 8.2 1.4 1.3 2.5 0.9 0.9 0.9 0.8 0.6 1.6 0.9 0.7 0.0 0.1 0.7 3.1 3.6 0.0 0.0 0.1 5.0 1.0 1.3 2.4 0.3 0.2 4.5 10.1 1.3 2.0 2.1 0.2 0.4 1.6 0.4 6.1 0.1 0.1 4.3 0.0 0.7 0.8 2.9 0.0 0.0 0.1 0.1 1.8 1.0 0.0 5.5 3.4 1.1 1.6 0.0 0.1 0.1 0.0 7.4 0.1 0.2 0.0 0.1 2.2 0.0 0.2 0.0 0.4 0.5 0.2 0.1 0.1 1.8 0.1 41.4 0.0 1.4 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.1 0.4 0.1 0.0 0.1 9.0 0.0 0.0 0.2 0.5 0.0 0.3 0.2 2.7 12.6 0.1 0.0 0.0 5.5 0.0 1.4 6.2 4.0 0.0 0.0 12.6 0.0 46.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 1.5 5.8 1.4 0.6 1.6 0.7 3.1 1.0 0.2 6.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.6 0.6 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 1.5 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.7 0.1 0.0 0.0 11.5 1.8 0.9 3.4 0.0 0.3 0.1 0.0 2.6 0.0 0.5 GFER "ALR, ERV1, HERV1, HPO1, HPO2, HSS" ENSG00000127554 "Growth factor, augmenter of liver regeneration" P55789 16 1984193-1987749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Oxidoreductase" "Cataract, Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 183.7;Early spermatids: 168.7;Proximal enterocytes: 371.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041227, HPA063553" Approved Enhanced Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Mitochondria, Cytosol" "HPA041227: AB_10795538, HPA063553: AB_2685038" "unprognostic (5.35e-2)" "unprognostic (2.11e-2)" "unprognostic (3.08e-1)" "unprognostic (4.42e-2)" "unprognostic (3.15e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (5.93e-2)" "prognostic favorable (4.06e-4)" "unprognostic (4.93e-2)" "unprognostic (3.64e-1)" "unprognostic (3.56e-1)" "unprognostic (1.09e-2)" 17.7 21.2 19.6 13.8 19.0 18.2 17.8 21.6 23.1 14.2 17.9 32.8 42.7 16.6 6.6 17.5 16.0 13.5 29.8 19.0 19.7 21.9 45.9 15.3 20.9 21.5 21.1 11.3 53.7 29.6 18.1 12.2 20.9 19.6 25.4 7.7 28.8 13.1 40.9 14.5 45.2 10.9 18.8 21.9 24.7 38.5 20.6 10.5 15.9 30.4 16.9 19.4 12.8 20.6 27.2 44.1 35.6 29.2 14.7 28.9 43.5 28.6 31.2 44.2 35.6 63.7 46.1 15.2 39.7 24.2 25.7 39.8 27.3 42.4 27.9 44.7 46.6 20.9 44.3 73.4 26.6 32.1 37.9 18.9 32.5 38.8 34.6 27.8 21.1 32.7 33.0 51.3 32.6 66.1 34.9 33.9 54.9 23.9 39.7 74.5 26.8 50.7 45.5 21.9 30.5 28.9 39.3 91.2 34.5 18.2 43.4 33.6 19.1 42.8 45.0 24.0 54.3 79.1 48.3 45.7 14.2 21.5 36.7 3.8 16.2 13.4 11.2 13.9 11.4 23.5 14.9 18.5 11.6 17.8 13.6 9.5 1.4 10.7 17.4 5.1 24.9 10.6 19.6 19.0 21.6 23.1 19.0 19.7 21.5 21.1 20.9 18.8 20.6 20.6 18.0 3.2 6.7 2.3 32.5 15.9 19.9 21.1 17.6 10.8 32.7 27.6 17.4 27.1 16.6 9.2 0.0 43.4 23.0 183.7 35.2 44.0 168.7 24.0 11.4 17.9 27.2 17.0 3.4 80.8 57.8 17.7 16.8 18.7 12.7 22.8 20.7 59.1 45.9 8.4 3.2 60.3 26.4 39.3 24.8 123.7 17.4 24.7 23.2 1.0 39.6 12.6 39.1 1.5 3.3 57.3 100.3 12.4 39.6 21.7 371.7 84.6 33.3 11.5 13.1 15.8 18.5 41.9 26.7 17.3 14.8 37.5 27.4 26.7 68.7 26.0 GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 100.9;Cardiomyocytes: 108.2;Excitatory neurons: 133.2;Inhibitory neurons: 106.2;NK-cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Cell line enhanced" "Detected in many" "HEL: 30.5;HMC-1: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: AB_10602320" "unprognostic (5.00e-2)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.29e-5)" "unprognostic (8.49e-2)" "unprognostic (1.95e-3)" "unprognostic (1.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.34e-2)" "unprognostic (3.11e-2)" "unprognostic (6.49e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.72e-5)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (4.66e-3)" 10.5 2.0 14.3 2.8 21.6 12.7 9.6 11.2 26.1 5.0 0.0 6.2 1.8 3.6 0.8 8.6 4.4 4.3 16.7 24.5 3.7 2.3 7.2 9.7 4.3 3.0 1.5 1.5 1.5 1.7 3.5 3.9 2.3 4.0 2.8 2.1 3.6 1.4 12.0 5.5 6.5 4.9 0.6 8.8 7.9 0.6 2.5 3.0 2.7 9.7 4.2 6.2 5.8 16.9 12.5 1.3 1.0 2.1 1.7 1.8 1.3 1.0 0.5 0.7 0.4 0.4 0.9 16.8 16.6 1.2 1.0 10.9 3.4 5.4 0.7 1.2 6.0 30.5 7.2 6.6 2.4 9.0 46.3 0.9 4.1 1.6 4.5 2.6 9.5 4.5 0.9 1.5 1.3 4.1 2.0 5.2 1.8 4.3 3.3 6.9 2.1 8.8 0.6 2.4 5.5 1.0 4.0 0.7 4.0 2.1 0.9 0.9 12.2 1.6 3.2 3.5 5.6 13.4 8.3 19.8 1.4 5.3 0.4 0.2 0.4 15.5 1.5 0.9 0.2 2.7 0.2 0.7 0.2 1.9 0.1 0.5 0.3 13.1 0.9 0.1 0.1 1.0 14.3 21.6 11.2 26.1 24.5 3.7 3.0 1.5 2.3 0.6 2.5 16.9 100.9 0.0 1.8 33.0 14.3 20.3 4.9 14.5 19.9 43.8 7.4 3.7 108.2 10.0 14.4 0.0 0.0 1.5 46.1 18.2 0.0 5.3 0.1 3.8 1.0 49.0 8.4 31.2 133.2 3.1 34.7 9.1 2.0 8.0 4.5 0.2 51.4 19.5 2.5 1.7 106.2 11.2 8.2 15.7 31.3 0.3 2.5 21.4 12.4 42.2 4.7 2.1 142.2 58.8 56.6 30.5 31.7 1.2 14.5 3.1 10.6 0.3 13.6 2.7 13.1 19.9 17.5 0.0 3.3 34.6 22.4 0.7 23.4 1.0 4.4 4.7 GFOD2 "FLJ23802, MGC11335" ENSG00000141098 "Glucose-fructose oxidoreductase domain containing 2" Q3B7J2 16 67674531-67719339 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040939, HPA041112" Uncertain Supported Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA040939: AB_10796564, HPA041112: AB_10794541" "unprognostic (9.80e-2)" "unprognostic (2.20e-1)" "unprognostic (2.06e-2)" "unprognostic (3.16e-3)" "unprognostic (4.62e-2)" "unprognostic (1.38e-1)" "unprognostic (2.93e-2)" "unprognostic (5.61e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.17e-1)" "prognostic favorable (8.66e-4)" "unprognostic (1.90e-1)" "unprognostic (1.76e-1)" "unprognostic (7.87e-2)" "unprognostic (9.64e-2)" 12.5 12.2 13.4 6.9 13.8 16.6 12.6 27.4 14.8 17.6 13.4 11.8 11.7 10.8 5.5 33.5 13.0 7.9 7.2 13.0 13.9 12.4 40.8 9.3 8.7 11.3 12.9 6.4 8.9 12.0 13.2 14.7 13.6 10.9 9.3 8.1 12.7 7.3 9.2 16.7 9.2 9.2 8.8 18.5 8.0 11.1 12.6 8.1 10.3 7.1 12.9 10.9 26.3 11.5 15.8 25.1 15.1 31.0 14.9 11.3 18.1 12.7 16.5 23.3 23.9 21.5 13.9 26.6 11.8 14.8 12.6 19.4 15.6 14.9 19.3 16.2 20.1 6.7 14.5 30.4 11.4 11.0 12.5 9.1 16.9 31.0 9.2 11.7 34.5 26.9 14.1 4.9 13.2 33.0 18.2 13.4 20.7 9.4 13.8 28.7 8.9 20.8 14.5 21.5 30.4 18.4 31.6 10.5 9.6 8.7 15.9 7.3 26.4 17.8 18.1 16.3 13.0 13.2 19.8 29.0 11.1 15.8 13.3 0.5 4.8 5.2 4.4 2.9 7.2 6.3 7.7 7.9 4.8 7.0 6.6 5.3 9.0 5.9 3.1 5.4 9.2 3.7 13.4 13.8 27.4 14.8 13.0 13.9 11.3 12.9 13.6 8.8 12.6 11.5 36.1 0.0 8.4 8.5 7.7 22.9 15.8 8.1 15.9 13.7 21.7 12.4 5.3 15.7 10.9 11.0 14.6 10.3 10.6 23.8 5.9 21.1 89.6 22.5 10.9 33.8 43.2 56.6 18.3 11.6 24.1 10.4 3.6 8.7 4.5 12.2 31.1 46.7 6.6 21.9 16.8 17.0 16.2 7.5 10.0 29.9 8.7 4.6 8.8 6.5 5.2 12.0 11.3 8.5 7.3 15.8 14.2 11.3 9.1 12.4 20.6 13.0 24.5 11.0 6.6 11.9 11.4 19.9 14.8 10.1 27.3 22.2 10.3 9.3 18.3 21.3 GH1 "GH, GH-N, GHN, hGH-N" ENSG00000259384 "Growth hormone 1" P01241 17 63917200-63918839 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 868 "pituitary gland: 59365.3" "Cell type enhanced" "Detected in single" "Adipocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043715 Supported "Secreted to blood" NA NA 2690000 6400000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 57: B-cells - Immune response" "HPA043715: AB_2678632" "unprognostic (1.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-1)" "unprognostic (9.45e-4)" "unprognostic (2.48e-1)" "unprognostic (2.09e-4)" "unprognostic (2.03e-2)" "unprognostic (6.57e-2)" "unprognostic (2.33e-1)" 14.8 68.3 0.1 0.0 0.1 0.1 2.1 0.1 0.6 1.9 0.1 3.7 0.5 4.1 0.0 9.5 2.8 0.0 7.8 0.1 0.4 4.1 18.4 3.5 0.0 0.1 0.1 6.1 7.7 0.0 59365.3 0.8 0.1 5.5 0.0 0.0 4.8 0.0 3.5 36.2 3.9 0.0 0.1 7.7 11.8 7.2 0.1 0.3 5.4 0.1 0.0 1.5 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 GH2 "GH-V, GHL, GHV, hGH-V" ENSG00000136487 "Growth hormone 2" P01242 17 63880215-63881944 "Cancer-related genes, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 79 "pituitary gland: 102.4;placenta: 127.5" "Group enriched" "Detected in some" 23 "Extravillous trophoblasts: 8.6;Syncytiotrophoblasts: 23.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "BEWO: 8.4" HPA043715 Supported "Secreted to blood" NA NA 4200000 "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA043715: AB_2678632" "unprognostic (1.02e-1)" 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 102.4 127.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 23.7 0.0 0.0 0.0 0.0 GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;liver: 213.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.3;Hepatocytes: 141.3;Inhibitory neurons: 115.7;Oligodendrocyte precursor cells: 181.0" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HSkMC: 21.2;T-47d: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 2200000 24000000 "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" 84.7 5.6 1.8 1.7 2.1 0.2 30.1 1.7 1.7 5.2 2.3 5.8 1.1 4.5 4.6 3.9 5.4 5.2 8.9 1.8 5.6 11.8 213.3 4.0 1.3 1.0 2.0 7.5 2.1 5.5 1.2 4.8 1.4 11.1 5.7 0.4 3.7 4.7 45.7 5.6 4.3 4.0 1.1 4.0 6.1 1.7 3.4 2.3 4.6 11.6 0.9 5.0 5.8 1.4 0.0 0.0 0.6 5.0 3.3 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.3 4.3 0.0 0.0 2.6 0.0 0.1 0.0 0.6 0.0 0.0 21.2 7.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 3.5 0.6 56.0 0.1 3.0 4.8 2.1 2.6 0.5 0.5 0.0 0.0 0.5 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.7 1.7 1.8 5.6 1.0 2.0 1.4 1.1 3.4 1.4 17.2 0.0 0.5 14.7 0.4 4.7 4.5 17.8 10.2 0.6 9.7 16.0 18.6 1.5 1.9 1.8 0.0 17.4 0.5 2.8 1.9 0.0 5.1 0.5 9.4 4.8 3.0 5.3 53.3 0.2 2.2 23.8 0.5 0.3 0.0 1.1 6.1 141.3 1.9 0.0 115.7 1.9 0.0 3.0 1.8 2.8 18.6 0.7 1.8 36.5 0.0 0.7 0.0 181.0 3.6 0.2 1.7 12.0 0.0 5.2 0.0 9.6 0.6 0.4 13.1 18.7 15.1 0.7 0.3 2.9 3.7 40.2 0.5 49.4 2.2 0.9 GHRH GHRF ENSG00000118702 "Growth hormone releasing hormone" P01286 20 37251086-37261814 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 199.5" "Cell type enriched" "Detected in single" 7 "Cardiomyocytes: 5.2" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 8.5" "Region enriched" "Detected in some" 12 "hypothalamus: 199.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 2.1;U-266/84: 7.9" "Region enriched" "Detected in many" 9 "hypothalamus: 32.9" "Region enhanced" "Detected in some" "hypothalamus: 3.7" "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (4.78e-2)" "unprognostic (2.57e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-1)" 0.0 1.0 0.6 0.0 0.3 0.0 0.3 0.4 0.5 0.0 0.2 0.0 3.4 0.0 0.0 0.3 0.0 0.0 12.5 0.4 199.5 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.3 0.0 0.6 0.1 17.1 9.2 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.4 0.5 0.4 199.5 0.3 0.4 0.3 0.3 17.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 GHRL "ghrelin, MTLRP, obestatin" ENSG00000157017 "Ghrelin and obestatin prepropeptide" Q9UBU3 3 10285666-10292947 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "stomach 1: 356.1" "Cell type enriched" "Detected in many" 52 "Gastric mucus-secreting cells: 1123.8" "Cancer enhanced" "Detected in some" "stomach cancer: 3.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 17.5;classical monocyte: 11.0;eosinophil: 12.4;myeloid DC: 41.8;neutrophil: 25.7;plasmacytoid DC: 28.5" "Group enriched" "Detected in many" 6 "dendritic cells: 41.8;granulocytes: 25.7;monocytes: 11.0" "Cell line enhanced" "Detected in many" "Karpas-707: 14.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA014246, CAB022731" Enhanced "Secreted to blood" NA NA 2580000 350000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB022731: , HPA014246: AB_1849659" "unprognostic (1.74e-2)" "unprognostic (3.01e-4)" "unprognostic (3.75e-1)" "unprognostic (1.05e-2)" "unprognostic (2.94e-2)" "unprognostic (1.60e-3)" "unprognostic (2.12e-1)" "unprognostic (1.06e-3)" "unprognostic (3.85e-1)" "unprognostic (5.45e-3)" "unprognostic (1.54e-3)" "unprognostic (2.71e-2)" "unprognostic (1.64e-3)" "unprognostic (4.52e-2)" "unprognostic (8.56e-2)" "unprognostic (2.14e-1)" "unprognostic (1.79e-4)" 0.5 0.5 3.5 3.1 4.1 4.4 1.5 4.0 7.6 0.5 3.0 2.2 19.0 0.7 4.8 1.8 0.7 2.3 1.3 3.3 2.8 0.9 1.4 1.0 7.4 3.2 2.8 1.3 4.1 0.7 0.7 0.5 3.5 1.0 0.6 2.0 1.4 0.3 2.0 2.1 3.1 0.9 2.0 2.5 356.1 1.1 2.7 1.3 1.3 0.2 3.1 1.4 0.5 2.9 0.6 0.2 2.6 2.0 1.8 0.0 4.8 2.4 0.0 0.7 0.2 2.9 0.5 1.5 0.9 0.1 2.1 0.4 0.0 0.6 0.0 0.4 2.9 3.1 2.1 6.3 0.0 3.2 5.3 0.3 0.0 0.0 0.1 0.2 0.5 1.9 1.3 14.4 0.0 0.7 1.2 4.3 1.3 0.5 5.3 0.8 0.2 0.8 0.0 2.4 1.9 0.3 1.6 1.1 0.1 1.7 1.1 3.8 2.6 1.2 0.7 1.1 1.7 1.7 2.6 2.9 0.4 3.5 0.5 17.5 11.0 12.4 0.2 5.5 0.1 2.1 0.2 0.0 41.8 1.0 0.3 0.1 25.7 4.4 0.4 28.5 0.2 3.8 3.5 4.1 4.0 7.6 3.3 2.8 3.2 2.8 3.5 2.0 2.7 2.9 0.6 0.0 1.1 1.3 4.9 1.3 4.6 0.2 0.0 7.8 0.8 0.6 0.3 0.0 0.2 1.8 10.4 1.7 10.5 0.5 0.0 1.0 0.3 0.2 0.7 1.5 0.0 0.0 1.0 1.3 1.5 1.0 1123.8 0.8 0.0 0.6 1.8 0.1 1.8 3.3 0.6 0.1 0.0 3.8 8.8 1.0 0.3 5.7 1.8 2.8 7.4 2.2 21.6 0.0 0.7 0.9 0.1 0.4 0.7 4.9 1.5 0.2 0.2 9.1 6.6 4.0 0.9 1.7 1.3 0.0 0.6 0.3 4.0 0.7 0.8 2.2 GIP ENSG00000159224 "Gastric inhibitory polypeptide" P09681 17 48958554-48968596 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 209 "intestine: 259.5" "Cell type enriched" "Detected in single" 4 "Intestinal goblet cells: 1.9" "Cancer enriched" "Detected in some" 63 "testis cancer: 74.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 6.6;BEWO: 5.9;Hep G2: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021612, HPA064596" Enhanced "Secreted to blood" NA NA 33900 540000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "HPA021612: AB_1849506, HPA064596: " "unprognostic (2.95e-1)" "unprognostic (2.70e-3)" "unprognostic (4.42e-2)" "unprognostic (1.82e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 259.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 93.7 0.0 0.0 0.0 1.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.3 0.5 5.9 0.3 0.0 0.0 0.0 1.7 0.7 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 9.8 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GKN1 "AMP18, BRICD1, CA11" ENSG00000169605 "Gastrokine 1" Q9NS71 2 68974573-68980980 "Plasma proteins, Predicted secreted proteins" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1840 "stomach 1: 37425.0" "Cell type enriched" "Detected in some" 28 "Gastric mucus-secreting cells: 9780.9" "Cancer enriched" "Detected in some" 116 "stomach cancer: 255.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 6.5;HMC-1: 17.2;MOLT-4: 12.4;NTERA-2: 16.0;REH: 7.2;U-2 OS: 10.1;U-266/70: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA047684 Enhanced "Secreted to digestive system" NA NA 18000000 "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA047684: AB_2680120" "unprognostic (5.40e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.54e-1)" "prognostic favorable (4.53e-4)" 3.0 1.8 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 0.0 1.4 0.0 0.3 0.0 3.6 0.4 0.0 1.0 0.0 0.0 1.8 0.8 3.5 0.0 0.0 0.0 0.4 4.8 0.0 0.3 20.3 0.0 0.7 0.3 0.0 0.4 0.1 1.0 0.5 0.4 0.0 0.0 10.4 37425.0 0.4 0.0 1.1 0.2 0.2 0.1 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 6.5 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.4 0.0 16.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 10.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 3.3 9780.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.5 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.5 0.0 0.0 GKN2 "blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465" ENSG00000183607 "Gastrokine 2" Q86XP6 2 68945232-68952893 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "stomach 1: 4612.5" "Cell type enriched" "Detected in some" 22 "Gastric mucus-secreting cells: 2770.2" "Cancer enriched" "Detected in some" 8 "stomach cancer: 43.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;HaCaT: 1.1;HMC-1: 2.0;MOLT-4: 1.6;NTERA-2: 2.3;PC-3: 4.5;U-2 OS: 1.6;U-266/70: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA057765 Enhanced "Secreted to digestive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA057765: AB_2683520" "unprognostic (1.81e-1)" "unprognostic (1.44e-4)" "unprognostic (2.22e-1)" 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.2 0.1 80.8 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 1.4 4612.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 2.3 0.0 4.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.2 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 115.4 109.3 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.9 2770.2 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 121.2 0.0 0.0 10.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 GLB1L MGC10771 ENSG00000163521 "Galactosidase beta 1 like" Q6UWU2 2 219236598-219245478 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 52.3" "Cell type enhanced" "Detected in many" "Early spermatids: 41.5;Spermatocytes: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 19.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043058 Enhanced "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA043058: AB_10806375" "unprognostic (4.30e-2)" "unprognostic (6.93e-2)" "unprognostic (2.68e-2)" "unprognostic (2.08e-3)" "unprognostic (4.35e-2)" "unprognostic (1.51e-1)" "unprognostic (1.67e-3)" "unprognostic (3.32e-2)" "unprognostic (4.77e-1)" "unprognostic (2.39e-1)" "unprognostic (8.48e-3)" "unprognostic (3.27e-1)" "unprognostic (3.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.23e-3)" "unprognostic (1.33e-1)" "unprognostic (8.50e-2)" 4.6 4.8 3.1 4.0 3.4 4.5 5.3 3.3 3.0 5.3 14.7 3.1 3.1 5.9 11.4 2.5 23.1 9.0 2.2 3.0 3.7 13.6 3.1 5.3 3.0 5.5 7.0 7.1 3.1 14.4 6.8 8.5 4.5 5.6 3.7 8.0 4.5 4.8 0.9 4.6 4.1 5.8 4.4 4.9 2.8 52.3 3.7 3.4 8.4 1.0 3.4 5.9 2.1 5.6 2.8 4.8 7.4 5.9 8.0 9.8 3.7 4.6 9.7 5.7 5.3 1.9 7.7 0.9 4.1 4.1 4.3 1.5 1.9 4.6 4.5 2.6 3.6 2.9 6.9 4.5 19.7 1.1 4.4 11.4 2.9 5.4 3.3 13.5 5.3 4.3 1.8 5.3 5.4 4.0 2.5 2.7 1.3 1.0 1.3 2.5 4.1 4.0 11.5 1.6 4.7 4.2 3.9 5.3 4.3 4.9 8.4 2.6 4.1 4.7 5.8 2.8 2.6 5.0 1.7 1.5 8.8 1.2 12.3 1.9 5.1 0.3 0.7 6.4 0.4 0.4 0.5 0.7 2.1 1.0 1.1 0.7 2.1 1.0 5.4 0.9 0.2 1.7 3.1 3.4 3.3 3.0 3.0 3.7 5.5 7.0 4.5 4.4 3.7 5.6 3.2 3.2 5.1 3.3 1.3 1.8 2.6 3.6 0.6 4.7 4.9 5.6 1.9 1.5 6.3 3.7 12.5 3.4 1.9 1.1 3.9 3.8 41.5 15.7 3.9 4.2 4.9 1.3 0.9 1.8 2.2 8.4 1.1 2.2 0.0 2.7 8.6 1.3 14.5 3.3 1.1 3.2 2.0 5.6 2.4 25.6 10.8 4.4 8.8 1.9 2.7 5.0 3.1 1.0 0.5 2.1 3.3 6.4 1.8 2.7 6.5 16.5 23.9 10.2 6.6 3.8 2.2 117.4 9.7 1.8 1.7 1.4 2.0 7.0 2.4 1.7 GLB1L2 ENSG00000149328 "Galactosidase beta 1 like 2" Q8IW92 11 134331874-134378341 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 160.6" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 182.0" "Cancer enhanced" "Detected in many" "prostate cancer: 21.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;NK-cell: 3.1" "Group enriched" "Detected in many" 24 "NK-cells: 3.1;T-cells: 3.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 49.9;HaCaT: 52.6;OE19: 123.6;SCLC-21H: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054808, HPA059955" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA054808: AB_2682608, HPA059955: AB_2684178" "unprognostic (2.63e-2)" "unprognostic (9.77e-3)" "unprognostic (2.32e-2)" "unprognostic (2.20e-2)" "unprognostic (8.07e-2)" "unprognostic (1.54e-1)" "unprognostic (5.98e-2)" "unprognostic (2.08e-2)" "unprognostic (1.51e-1)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (1.48e-1)" "unprognostic (4.73e-2)" "unprognostic (1.22e-2)" "unprognostic (2.64e-1)" "unprognostic (3.88e-3)" "unprognostic (1.01e-1)" 1.5 2.1 3.0 2.6 2.1 0.3 7.0 0.1 7.7 5.9 14.7 27.6 5.7 33.9 2.1 3.5 25.6 2.8 1.2 8.5 0.3 20.7 0.6 3.6 0.6 1.0 0.8 13.7 10.6 25.0 14.1 1.5 1.0 34.5 11.7 160.6 9.1 25.2 1.0 9.4 4.0 4.4 0.1 0.6 9.0 8.3 0.7 0.5 22.7 0.2 0.6 6.7 5.0 1.3 16.0 1.6 8.2 4.7 0.0 0.0 5.5 0.0 0.0 0.0 0.0 13.3 49.9 0.0 16.3 0.0 6.8 52.6 25.2 0.4 0.0 0.0 23.9 0.0 6.7 0.6 2.2 0.0 28.4 0.3 0.7 0.0 0.0 0.0 0.1 7.6 26.3 0.0 0.0 15.3 4.4 3.0 4.7 123.6 18.2 0.0 0.0 1.5 14.1 11.0 34.9 13.1 11.4 14.2 0.0 1.2 18.4 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.1 0.0 3.1 0.0 0.0 0.0 3.2 0.0 1.2 0.0 0.6 1.2 0.0 0.1 0.9 1.4 0.0 3.1 0.0 0.0 0.0 0.5 3.0 2.1 0.1 7.7 8.5 0.3 1.0 0.8 1.0 0.1 0.7 1.3 0.2 0.0 1.8 0.3 0.4 2.2 5.2 1.0 1.8 6.2 7.2 7.9 1.6 1.5 2.5 0.0 41.7 0.2 3.4 19.5 0.0 2.5 2.1 7.9 22.1 1.2 9.0 0.0 1.6 2.4 1.0 3.6 4.1 2.2 0.0 41.9 0.0 0.2 0.2 5.0 1.2 5.9 0.0 0.0 0.3 6.8 1.2 0.3 5.4 1.0 0.0 10.8 1.0 1.0 0.3 2.2 6.3 0.7 2.2 8.1 3.0 8.4 10.1 182.0 0.0 3.7 2.3 2.6 4.6 1.9 0.9 0.1 2.5 3.4 11.5 2.7 GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 84.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 510.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.7;MCF7: 1.3;SuSa: 1.8;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 410000 "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: AB_2684018" "unprognostic (5.04e-2)" "unprognostic (2.57e-2)" "unprognostic (5.15e-5)" "unprognostic (3.21e-3)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (2.07e-4)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.30e-2)" "unprognostic (3.15e-1)" "unprognostic (2.14e-2)" "unprognostic (9.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (3.80e-3)" "unprognostic (1.37e-1)" 18.5 2.3 18.1 1.6 51.1 0.7 9.7 35.0 28.6 1.8 0.0 3.5 0.2 0.5 0.5 0.5 1.2 3.4 5.0 15.5 31.2 0.4 0.1 8.7 0.2 47.6 48.9 0.5 0.5 0.4 0.6 3.9 56.4 2.4 6.4 1.3 1.4 0.7 1.0 5.0 0.6 0.6 26.0 2.9 2.1 0.2 41.7 0.1 0.8 0.9 0.2 1.5 1.5 84.8 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 1.0 0.0 1.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.3 2.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 18.1 51.1 35.0 28.6 15.5 31.2 47.6 48.9 56.4 26.0 41.7 84.8 40.1 0.0 2.6 2.0 0.0 6.2 0.0 0.3 0.0 9.2 0.2 0.3 8.4 0.0 0.1 0.0 0.0 5.2 0.0 47.0 0.0 0.0 0.0 0.0 0.1 3.7 1.2 0.0 7.4 0.0 0.6 7.9 4.6 0.2 0.0 4.5 0.0 0.2 4.9 0.0 17.2 1.7 0.0 14.9 9.5 0.0 0.3 16.1 3.6 42.2 0.0 0.3 0.0 2.0 510.8 0.1 28.6 0.0 0.0 0.1 0.0 0.1 0.9 0.8 0.0 4.7 9.8 0.1 0.1 0.0 4.0 100.4 0.6 0.4 5.1 1.6 GLIPR1L1 MGC26856 ENSG00000173401 "GLIPR1 like 1" Q6UWM5 12 75334670-75370560 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 33.6" "Group enriched" "Detected in some" 7 "Early spermatids: 226.7;Spermatocytes: 179.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "NTERA-2: 109.1" "Low region specificity" "Detected in many" HPA042095 Enhanced "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA042095: AB_10796898" "unprognostic (2.45e-3)" "unprognostic (1.56e-1)" "unprognostic (4.40e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (3.04e-1)" "unprognostic (2.70e-1)" "unprognostic (4.79e-2)" "unprognostic (3.01e-1)" "unprognostic (2.89e-1)" "unprognostic (7.90e-3)" "unprognostic (1.08e-1)" "unprognostic (9.13e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "unprognostic (2.00e-1)" "unprognostic (2.11e-2)" 0.2 0.8 0.6 0.1 2.0 0.3 0.1 3.9 1.0 0.2 0.5 0.1 0.2 0.5 0.0 0.8 0.2 0.8 1.3 0.5 1.9 0.6 0.1 0.4 0.4 1.8 1.6 0.6 0.2 0.0 0.5 0.0 1.7 0.3 0.0 1.1 0.6 0.0 0.5 1.1 0.3 0.0 0.9 0.4 0.3 33.6 2.2 0.0 0.3 0.0 0.0 0.2 0.1 2.0 0.5 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.9 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.2 109.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.7 0.3 0.0 0.0 0.2 14.5 0.1 0.2 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.6 2.0 3.9 1.0 0.5 1.9 1.8 1.6 1.7 0.9 2.2 2.0 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.6 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 226.7 0.1 0.3 0.5 0.0 0.0 4.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 28.3 5.3 0.3 0.0 1.9 0.0 0.3 0.0 5.0 5.1 0.0 0.0 2.6 0.0 0.0 0.0 0.3 0.0 0.3 6.6 0.2 0.2 179.3 2.2 0.1 0.0 0.0 0.2 0.2 0.0 0.0 GLT1D1 FLJ31978 ENSG00000151948 "Glycosyltransferase 1 domain containing 1" Q96MS3 12 128853427-128984968 "Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.1;liver: 27.6" "Cell type enhanced" "Detected in some" "Early spermatids: 14.6;Excitatory neurons: 37.6;Inhibitory neurons: 30.2;Late spermatids: 41.7;Oligodendrocyte precursor cells: 34.7" "Group enriched" "Detected in some" 6 "liver cancer: 6.2;testis cancer: 2.6;thyroid cancer: 4.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.4" "Group enriched" "Detected in some" 7 "MOLT-4: 13.0;NTERA-2: 17.9;SCLC-21H: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039051, HPA039052" Enhanced Cytosol "Secreted to blood" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA039051: AB_10673299, HPA039052: AB_10672839" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (3.60e-2)" "unprognostic (3.47e-3)" "unprognostic (2.88e-1)" "unprognostic (2.53e-1)" "unprognostic (4.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (3.93e-5)" "unprognostic (2.39e-2)" "unprognostic (2.20e-1)" "unprognostic (1.55e-3)" "unprognostic (2.41e-1)" 2.5 0.2 7.0 6.8 7.3 28.1 0.2 1.5 9.8 2.4 5.6 0.4 0.1 3.6 1.0 0.5 3.0 1.7 0.8 7.1 11.1 0.8 27.6 2.8 0.3 2.9 2.6 0.2 0.8 0.6 1.4 0.7 3.1 0.8 0.3 5.7 0.2 1.5 9.0 1.1 0.3 3.1 1.2 12.7 0.3 15.5 4.3 0.9 1.7 9.6 0.4 1.4 0.5 6.8 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.3 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.5 3.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 36.4 0.0 2.0 2.3 0.0 1.6 7.0 7.3 1.5 9.8 7.1 11.1 2.9 2.6 3.1 1.2 4.3 6.8 0.0 0.0 0.0 1.6 0.4 0.9 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.0 0.0 0.0 2.1 0.0 4.7 0.0 0.0 0.1 14.6 0.6 2.3 0.1 0.0 0.0 37.6 0.0 0.0 0.4 0.0 4.8 0.0 0.1 1.1 10.4 1.4 0.0 30.2 0.0 0.0 8.5 0.0 41.7 0.3 9.4 1.8 6.5 12.4 10.4 1.0 34.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.3 0.0 0.2 0.2 4.0 0.6 0.0 0.3 0.1 0.2 0.0 0.0 0.0 GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 73.8" "Group enriched" "Detected in some" 5 "Hepatocytes: 83.7;Proximal tubular cells: 135.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 25.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 3.4;CACO-2: 9.2;Hep G2: 13.7;MCF7: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 150000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA058295: AB_2683671, HPA065267: AB_2685451" "unprognostic (4.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.95e-3)" "unprognostic (1.70e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-4)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.33e-2)" "unprognostic (5.62e-4)" "unprognostic (7.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.79e-1)" "unprognostic (1.71e-4)" "unprognostic (7.59e-3)" 0.5 0.5 1.3 0.5 1.1 1.5 0.3 2.3 2.7 0.4 0.0 0.5 10.1 0.5 0.0 0.8 0.4 0.3 0.2 1.0 2.1 12.0 73.8 0.4 0.1 3.1 2.8 0.3 0.7 0.2 0.8 0.1 2.0 0.4 0.0 0.3 1.0 0.0 1.3 1.7 6.2 0.0 0.4 1.1 1.1 0.1 1.5 0.0 0.2 0.0 0.0 0.5 0.5 1.4 0.5 1.8 0.1 1.5 0.0 0.0 3.4 0.4 0.0 0.0 0.0 9.2 0.6 0.8 0.9 0.0 0.3 1.7 0.0 0.0 0.0 1.7 1.2 0.1 0.7 13.7 0.1 0.2 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.5 0.4 0.0 4.1 0.1 0.1 0.2 0.6 0.7 0.7 0.5 0.2 0.0 0.7 1.1 0.7 1.6 0.3 0.4 0.0 1.0 0.1 1.7 0.5 0.7 0.4 0.3 0.1 0.5 0.1 0.2 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.3 1.1 2.3 2.7 1.0 2.1 3.1 2.8 2.0 0.4 1.5 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.3 0.2 1.5 0.5 0.0 0.0 0.0 0.1 0.4 17.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.2 0.0 0.2 0.0 0.0 2.2 83.7 0.1 0.0 0.2 0.6 0.0 1.3 0.4 0.2 0.6 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.6 0.3 21.1 135.8 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.1 0.3 0.3 0.1 0.3 0.4 GNLY "D2S69E, LAG-2, LAG2, NKG5, TLA519" ENSG00000115523 Granulysin P22749 2 85685175-85698852 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 288.7;endometrium 1: 71.9;lymphoid tissue: 86.3" "Group enriched" "Detected in many" 5 "dendritic cells: 5070.6;NK-cells: 8318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 17623.2" "Group enriched" "Detected in all" 63 "NK-cells: 17623.2;T-cells: 7874.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025186, HPA058021" Enhanced "Secreted to blood" NA NA 2920000 17000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025186: , HPA058021: AB_2683581" "unprognostic (5.80e-2)" "unprognostic (5.64e-3)" "unprognostic (6.68e-2)" "prognostic favorable (3.48e-5)" "unprognostic (4.34e-2)" "unprognostic (9.22e-2)" "unprognostic (2.60e-1)" "unprognostic (2.79e-2)" "prognostic favorable (6.60e-5)" "unprognostic (2.61e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.46e-2)" "unprognostic (3.37e-1)" "unprognostic (1.86e-1)" "prognostic favorable (8.07e-4)" 6.9 2.7 8.1 11.6 7.8 288.7 5.2 8.1 18.7 4.3 7.1 5.7 4.0 71.9 3.9 2.6 6.1 6.5 4.3 7.8 9.8 2.9 10.4 36.8 21.9 12.7 11.6 1.5 1.2 0.8 1.8 17.0 10.6 2.0 6.1 0.5 2.0 5.3 9.2 1.5 10.3 4.3 8.8 86.3 5.0 0.9 9.8 3.5 3.6 3.5 17.6 6.4 2.5 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.1 0.0 177.1 26.2 17.7 7874.6 26.3 2145.8 34.2 837.4 3344.7 22.4 23.0 231.3 2928.7 202.5 17623.2 32.3 58.2 40.3 8118.6 8.1 7.8 8.1 18.7 7.8 9.8 12.7 11.6 10.6 8.8 9.8 9.8 26.8 12.8 78.9 0.0 23.3 7.0 0.2 0.0 0.0 0.1 7.2 3.7 3.0 10.0 6.2 0.0 2.1 2.3 5070.6 1.3 1.9 1.9 0.0 7.5 12.0 13.0 1.8 47.2 0.2 0.0 3.4 29.3 0.5 10.6 52.4 0.1 23.2 5.3 6.0 0.0 0.1 3.3 0.0 22.4 7.2 0.2 0.3 28.4 80.0 9.4 48.6 0.1 8318.3 0.0 0.1 0.0 1.2 0.0 247.4 0.1 2.4 9.5 3.6 0.2 0.0 7.0 5.4 0.2 0.6 0.6 7.7 1.1 1230.0 1.0 1.6 0.6 GNRH1 "GNRH, GRH, LHRH" ENSG00000147437 "Gonadotropin releasing hormone 1" P01148 8 25419258-25424654 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 9.9;Peritubular cells: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 21.1" "Group enriched" "Detected in many" 4 "basal ganglia: 19.7;hypothalamus: 12.1;olfactory bulb: 6.7" "Group enriched" "Detected in some" 23 "basal ganglia: 14.1;hypothalamus: 32.3" HPA027532 Supported "Secreted to blood" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA027532: AB_10612111" "unprognostic (6.49e-3)" "unprognostic (7.62e-2)" "unprognostic (2.90e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.53e-4)" "unprognostic (7.80e-3)" "unprognostic (2.97e-2)" "unprognostic (1.39e-1)" "unprognostic (7.99e-2)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.08e-9)" "unprognostic (7.98e-3)" "unprognostic (5.11e-2)" "unprognostic (3.49e-1)" "unprognostic (3.68e-2)" 5.1 2.3 5.4 1.4 8.8 3.0 4.9 7.7 7.2 9.0 6.4 6.7 1.9 4.2 4.7 5.7 6.2 1.8 7.7 5.4 15.8 6.0 3.2 6.8 2.2 6.5 6.2 8.6 4.0 0.6 4.7 1.4 6.8 8.3 1.7 9.2 5.4 1.7 3.1 8.6 5.9 1.0 5.2 7.0 4.3 4.6 6.7 1.9 4.4 1.0 1.7 5.7 8.5 8.1 1.0 1.5 4.0 2.2 1.4 4.7 1.7 3.7 1.4 1.1 1.7 1.5 1.1 1.3 0.8 2.1 2.6 3.8 1.2 0.3 2.7 1.7 3.3 1.4 5.9 1.5 1.1 0.2 1.4 2.6 2.1 0.8 0.7 3.6 0.9 1.3 1.5 1.1 1.8 0.6 1.4 3.2 1.4 1.2 0.5 0.9 0.6 0.6 1.0 0.7 21.1 0.7 1.1 0.7 1.4 1.5 0.7 1.8 3.4 3.1 1.5 3.8 1.5 0.3 0.2 1.8 1.5 1.0 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 5.4 8.8 7.7 7.2 5.4 15.8 6.5 6.2 6.8 5.2 6.7 8.1 2.4 0.0 0.5 3.3 1.1 5.0 1.9 1.7 5.2 3.6 2.5 1.3 1.8 1.5 1.4 3.7 4.2 0.1 1.0 2.3 0.0 0.2 0.3 0.7 0.6 2.1 1.8 0.0 3.0 0.6 0.4 3.1 0.0 1.0 0.0 1.0 1.4 0.3 0.5 0.0 2.8 0.5 0.0 0.8 2.2 0.5 9.9 0.4 3.6 2.8 0.8 0.6 4.1 1.5 1.7 0.6 0.6 9.8 1.8 3.7 1.8 0.2 0.9 3.9 0.0 2.4 1.9 1.8 1.2 3.4 2.4 0.1 1.4 0.5 1.4 1.8 GNRH2 ENSG00000125787 "Gonadotropin releasing hormone 2" O43555 20 3043622-3045747 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Early spermatids: 1.2;Excitatory neurons: 2.0;Inhibitory neurons: 2.0;Late spermatids: 1.8;Oligodendrocytes: 1.3;Sertoli cells: 6.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-266/84: 3.8" "Low region specificity" "Detected in many" HPA004338 Uncertain "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA004338: AB_1079012" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (1.20e-2)" "unprognostic (2.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.87e-2)" "unprognostic (1.36e-2)" "unprognostic (4.04e-3)" "unprognostic (7.00e-2)" "unprognostic (1.93e-2)" "unprognostic (2.47e-4)" "unprognostic (2.69e-1)" "unprognostic (2.98e-2)" "unprognostic (1.72e-1)" "unprognostic (3.29e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" 0.5 0.5 1.7 0.6 1.3 0.3 0.3 3.8 2.0 0.4 0.6 0.2 0.2 0.5 0.6 0.3 0.9 0.5 0.5 2.0 1.3 0.7 2.0 0.3 0.4 1.0 0.6 2.2 0.1 0.2 0.9 0.2 0.7 1.9 0.1 0.3 0.8 0.8 0.1 0.1 0.2 0.0 0.1 0.3 1.0 1.4 1.2 0.1 1.1 0.0 0.0 0.3 0.3 0.8 0.5 0.5 1.4 1.8 0.8 0.2 0.2 0.3 0.0 0.2 0.3 0.9 0.3 0.7 0.0 0.1 0.5 1.5 0.5 0.5 0.4 0.5 1.6 0.6 0.6 1.1 0.0 0.0 0.9 1.1 1.1 1.1 0.0 0.2 0.4 1.2 0.7 0.2 0.6 0.5 0.3 1.2 0.6 0.0 0.0 0.4 0.2 0.4 0.2 1.3 2.1 0.9 0.1 1.2 0.7 0.6 1.3 0.6 0.0 0.8 0.3 0.7 0.8 0.5 3.8 0.4 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.3 3.8 2.0 2.0 1.3 1.0 0.6 0.7 0.1 1.2 0.8 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GP2 ZAP75 ENSG00000169347 "Glycoprotein 2" P55259 16 20309574-20327808 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 966 "pancreas: 35381.6" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 504.1" "Cancer enriched" "Detected in many" 14 "pancreatic cancer: 320.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015739, HPA016668" Enhanced "Secreted to digestive system" NA NA 41000 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" "HPA015739: AB_1849905, HPA016668: AB_1849907" "unprognostic (2.14e-2)" "unprognostic (1.97e-2)" "unprognostic (5.68e-2)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.84e-1)" "unprognostic (6.35e-2)" "unprognostic (8.17e-3)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" 7.1 1.9 0.2 0.9 0.2 0.7 3.8 0.6 0.4 2.5 0.4 3.9 36.6 2.1 0.2 3.9 1.4 18.7 6.5 0.3 0.2 33.4 5.0 1.5 2.1 0.2 0.6 15.4 35381.6 0.0 2.9 2.4 0.3 33.4 6.2 0.1 7.5 0.0 1.6 1.8 10.1 0.1 0.1 2.5 27.4 1.9 0.2 0.1 1.3 0.0 0.2 1.0 1.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.4 0.3 0.2 0.2 0.6 0.3 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.2 1.1 0.1 0.1 87.2 0.0 0.0 0.0 0.0 0.0 1.7 9.8 1.3 7.5 0.3 0.5 0.2 0.0 0.0 0.0 504.1 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.1 0.0 0.0 0.3 15.6 0.3 0.4 0.0 0.0 4.2 0.2 0.0 0.0 0.0 20.7 13.9 0.4 0.0 69.7 2.0 0.0 0.0 0.3 0.0 0.5 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.1 19.9 2.1 GPHA2 "A2, GPA2, MGC126572, ZSIG51" ENSG00000149735 "Glycoprotein hormone subunit alpha 2" Q96T91 11 64934471-64935893 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pancreas: 360.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.5;Exocrine glandular cells: 17.4;Pancreatic endocrine cells: 2.4;Spermatocytes: 7.7;Spermatogonia: 3.2" "Cancer enriched" "Detected in some" 7 "testis cancer: 15.8" "Region enhanced" "Detected in single" "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "Hep G2: 21.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067068 Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA067068: " "unprognostic (1.13e-1)" "unprognostic (8.31e-3)" "unprognostic (1.51e-2)" "unprognostic (9.22e-4)" "unprognostic (7.88e-3)" "unprognostic (2.62e-1)" "unprognostic (1.45e-1)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.75e-1)" "unprognostic (5.03e-2)" "unprognostic (9.86e-3)" "unprognostic (1.70e-1)" 0.0 0.1 0.3 0.2 0.6 0.1 0.1 3.6 0.6 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.4 16.9 0.0 0.3 0.3 0.8 0.7 0.3 0.6 0.4 0.3 2.7 360.5 0.0 28.0 0.0 0.6 0.7 0.0 0.1 0.3 0.5 0.0 0.5 0.5 0.0 0.2 0.6 1.1 10.8 0.4 0.1 0.3 0.0 0.5 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 21.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.6 0.6 0.3 0.3 0.4 0.3 0.6 0.2 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.0 0.0 7.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 GPHB5 "GPB5, ZLUT1" ENSG00000179600 "Glycoprotein hormone subunit beta 5" Q86YW7 14 63312835-63318935 "Predicted secreted proteins" Hormone "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 46.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Excitatory neurons: 62.4;Hepatocytes: 66.8;Inhibitory neurons: 78.3;Oligodendrocyte precursor cells: 33.2" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 7.6;U-698: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" NA NA 103000000000 3100000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" 4.2 0.9 2.0 0.6 1.7 0.9 1.3 7.6 4.7 1.1 0.1 1.0 0.5 1.6 1.7 1.1 0.9 0.6 0.5 1.3 2.4 0.6 46.1 0.9 0.9 1.8 1.9 1.2 0.6 2.5 1.7 0.2 1.9 1.8 0.6 6.2 0.4 4.8 1.7 8.6 0.4 1.4 0.6 0.6 0.7 1.4 1.4 5.1 2.4 0.6 1.3 1.1 1.5 2.1 0.5 0.7 0.8 1.2 0.0 0.0 2.0 0.1 0.2 0.2 0.1 3.5 0.1 7.6 0.8 0.1 0.2 0.1 1.2 0.2 0.1 0.9 2.1 1.1 0.9 3.2 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.8 0.0 1.8 0.5 0.3 0.1 0.5 0.7 0.5 2.9 0.5 0.3 1.4 0.2 0.1 0.4 3.4 2.0 2.3 0.9 0.1 0.4 0.6 0.4 0.3 0.1 0.7 0.9 0.1 1.0 2.4 3.4 8.1 0.1 0.3 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 2.0 1.7 7.6 4.7 1.3 2.4 1.8 1.9 1.9 0.6 1.4 2.1 0.4 0.0 3.7 24.8 1.1 0.0 0.7 2.8 0.6 19.6 0.7 0.4 11.6 0.0 1.7 1.8 68.8 0.3 1.6 0.1 0.0 0.4 3.5 0.5 0.6 1.2 1.8 7.4 62.4 0.4 0.3 1.3 0.0 0.3 0.0 2.1 1.4 66.8 0.1 15.2 78.3 0.3 0.0 1.3 0.0 3.4 3.1 0.1 0.0 9.4 0.1 4.0 3.1 33.2 3.1 0.1 0.1 3.4 3.1 0.3 0.1 0.5 1.1 10.9 0.0 3.6 1.4 0.5 5.8 0.3 0.6 0.0 0.5 0.9 0.5 2.6 GPX3 ENSG00000211445 "Glutathione peroxidase 3" P22352 5 151020438-151028992 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 11673.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 20125.9" "Cancer enhanced" "Detected in all" "renal cancer: 605.6;thyroid cancer: 856.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 20.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.7" "Cell line enriched" "Detected in many" 12 "ASC diff: 7677.4" "Region enhanced" "Detected in all" "hypothalamus: 239.5" "Low region specificity" "Detected in all" CAB069456 Approved "Secreted to blood" NA NA 5090000000 6200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB069456: AB_1616682" "unprognostic (4.03e-1)" "unprognostic (7.35e-2)" "unprognostic (5.05e-3)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.13e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (5.75e-3)" "unprognostic (2.70e-3)" "unprognostic (8.17e-3)" "unprognostic (1.14e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (2.14e-1)" "unprognostic (5.11e-2)" "unprognostic (1.26e-1)" 4524.7 443.8 57.8 75.4 68.3 7.9 3188.6 62.7 73.8 917.6 578.2 741.2 88.3 416.0 90.7 568.6 1038.4 136.4 2362.4 68.2 117.5 11673.5 986.3 2471.8 133.2 317.7 104.5 517.8 257.0 112.4 793.7 592.2 136.6 557.5 93.4 4204.9 481.4 140.0 847.9 669.7 720.6 61.0 67.5 555.7 641.1 80.4 135.8 26.8 3627.5 458.9 44.9 1196.7 891.7 70.3 2.2 10.0 8.5 2.7 7677.4 6.7 9.2 3.5 0.8 7.9 2.4 177.5 3.9 1.1 214.1 5.6 3.2 2.8 39.6 433.2 6.0 6.1 2.5 1.9 4.3 195.0 294.7 0.5 4.3 649.1 41.2 0.2 1.0 10.6 11.3 1.2 1.2 0.3 11.0 31.4 0.5 1.2 13.8 0.8 0.2 1.0 5.2 1.7 74.1 4.3 11.3 11.4 1.2 31.6 1.9 33.6 43.5 2.1 2.5 2.3 19.6 3.7 1.0 2.7 15.6 2.5 7.0 3.0 0.6 0.0 4.3 0.1 0.0 1.6 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 20.7 0.0 0.2 0.0 0.0 1.6 57.8 68.3 62.7 73.8 68.2 117.5 317.7 104.5 136.6 67.5 135.8 70.3 353.6 9.6 33.7 1.0 106.8 18.5 86.9 94.8 1.2 26.3 31.7 5.5 639.8 18.6 58.3 649.2 43.8 713.8 2.2 2.3 1772.6 5.5 2.9 48.1 71.1 144.6 45.6 24.0 4.0 48.2 1191.3 514.0 50.0 627.9 11.4 274.9 735.3 228.4 151.5 16.8 0.4 5.9 91.6 47.9 86.7 17.5 446.7 160.2 23.2 3.7 0.7 5019.8 0.0 0.0 0.3 9.9 13.8 41.0 2.2 141.8 0.5 20125.9 39.1 86.8 683.7 131.6 264.6 7.1 10.3 13.9 21.6 1767.7 68.3 1.0 1.3 34.3 GPX5 ENSG00000224586 "Glutathione peroxidase 5" O75715 6 28525881-28534955 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 9.3" "Group enriched" "Detected in some" 46 "Early spermatids: 14.3;Late spermatids: 41.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.34e-2)" "unprognostic (3.74e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPX6 GPXP3 ENSG00000198704 "Glutathione peroxidase 6" P59796 6 28503296-28528215 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 15 "epididymis: 3.3" "Group enriched" "Detected in some" 6 "Early spermatids: 3.3;Late spermatids: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 16 "basal ganglia: 23.8" "Low region specificity" "Detected in single" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.99e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPX7 "FLJ14777, GPX6, NPGPx" ENSG00000116157 "Glutathione peroxidase 7" Q96SL4 1 52602371-52609051 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 68.6;HEL: 63.9;REH: 76.4;RPMI-8226: 130.0;THP-1: 101.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 25: RPMI-8226 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (7.43e-3)" "unprognostic (3.18e-1)" "unprognostic (5.64e-2)" "unprognostic (6.12e-3)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (8.18e-2)" "unprognostic (4.17e-1)" "unprognostic (2.48e-3)" "prognostic unfavorable (2.26e-5)" "unprognostic (1.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.08e-2)" "unprognostic (5.44e-2)" 8.4 7.9 4.8 12.4 5.0 18.3 11.9 5.2 5.4 11.6 9.3 9.4 3.3 13.1 7.3 4.3 9.1 13.4 10.8 4.6 5.9 6.9 5.3 6.8 16.5 5.2 5.1 8.9 11.5 8.5 12.5 29.3 5.0 8.7 5.5 1.7 5.9 9.7 12.1 5.0 6.0 10.8 5.0 8.1 5.0 5.5 5.0 15.9 17.1 11.5 14.0 12.4 6.9 4.9 0.1 0.0 18.1 33.9 6.6 19.1 0.1 12.5 0.7 14.8 15.3 12.2 0.0 0.1 9.8 68.6 0.0 0.0 29.0 0.0 8.1 0.0 0.2 63.9 3.6 11.3 23.9 0.0 0.0 44.4 0.0 2.5 0.0 0.0 22.9 0.4 0.0 0.0 28.2 0.0 3.3 33.5 31.5 0.0 0.0 76.4 0.0 130.0 1.3 0.0 13.7 27.0 33.3 0.0 21.9 3.0 0.0 101.1 1.4 0.0 3.7 3.8 0.1 0.1 0.0 47.9 0.0 0.2 11.3 0.2 1.7 5.4 22.6 0.4 31.8 32.0 34.6 27.1 5.4 35.2 44.5 29.0 0.9 31.6 0.2 73.7 27.6 21.4 4.8 5.0 5.2 5.4 4.6 5.9 5.2 5.1 5.0 5.0 5.0 4.9 8.4 3.2 5.5 1.0 16.1 2.2 9.0 8.3 1.2 1.0 7.1 13.6 3.9 12.8 6.5 3.7 0.0 22.8 9.2 0.2 5.9 11.1 6.9 8.2 43.7 12.4 1.2 6.7 1.6 15.6 19.8 30.5 0.5 6.5 1.3 25.8 15.4 3.8 12.3 5.0 2.7 1.2 2.0 1.9 0.7 6.6 15.2 6.0 7.2 4.7 5.0 8.3 9.2 4.5 2.0 4.7 0.7 13.5 25.2 5.7 0.0 3.0 7.0 0.6 13.1 13.3 14.5 10.8 12.1 1.9 3.3 15.6 10.9 19.3 0.6 4.9 GREM1 "CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS" ENSG00000166923 "Gremlin 1, DAN family BMP antagonist" O60565 15 32718004-32745106 "Disease related genes, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 113.0;smooth muscle: 68.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Granulosa cells: 121.1;Oligodendrocytes: 40.5;Skeletal myocytes: 181.4" "Cancer enhanced" "Detected in many" "stomach cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 294.7;BJ hTERT+: 468.5;BJ hTERT+ SV40 Large T+ RasG12V: 286.8;fHDF/TERT166: 957.0;hTEC/SVTERT24-B: 227.8" "Group enriched" "Detected in many" 5 "hippocampal formation: 3.2;olfactory bulb: 10.9" "Low region specificity" "Detected in many" HPA007526 Uncertain "Secreted to blood" NA NA 242000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA007526: AB_1849971" "unprognostic (4.74e-2)" "unprognostic (2.78e-1)" "unprognostic (4.63e-2)" "unprognostic (6.80e-2)" "unprognostic (3.58e-1)" "unprognostic (1.72e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (5.33e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-3)" "unprognostic (2.79e-1)" "unprognostic (2.13e-11)" "unprognostic (1.77e-2)" "unprognostic (6.60e-2)" "unprognostic (3.29e-2)" "unprognostic (1.16e-3)" 32.7 0.5 1.4 6.5 3.6 0.2 5.5 1.1 2.4 44.7 0.0 36.1 2.6 9.6 0.0 13.6 1.1 113.0 1.3 1.5 1.3 1.2 1.1 2.2 1.1 3.1 3.0 0.3 2.2 0.0 0.2 0.3 1.8 8.2 26.7 0.1 0.6 3.8 0.6 7.6 52.3 68.2 1.1 0.8 36.8 0.5 3.8 0.0 2.3 0.0 1.7 21.7 50.4 6.1 0.0 3.5 0.0 0.0 11.1 12.5 0.0 294.7 468.5 112.5 286.8 0.3 0.0 0.0 0.0 957.0 0.0 0.0 0.0 0.0 109.7 0.0 0.1 0.0 0.1 0.0 3.3 0.0 0.0 3.1 0.0 227.8 0.1 70.6 0.0 0.0 0.0 0.0 143.4 0.1 0.0 0.0 1.2 0.0 0.9 0.0 20.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.0 57.7 0.0 0.1 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.6 1.1 2.4 1.5 1.3 3.1 3.0 1.8 1.1 3.8 6.1 0.7 0.0 0.0 0.3 0.4 6.6 6.5 0.0 0.6 2.1 1.7 0.9 3.4 0.0 0.0 66.2 2.1 0.2 0.7 0.4 0.0 0.4 0.2 0.6 2.3 1.9 0.0 0.0 2.5 0.0 0.1 17.7 0.0 0.7 0.0 121.1 0.7 1.2 1.0 1.7 0.5 0.6 0.0 0.3 12.8 0.0 0.0 2.3 3.6 0.0 2.7 0.3 0.0 1.5 40.5 0.3 0.0 0.4 0.2 9.9 0.1 0.3 0.0 1.3 0.0 181.4 16.1 0.1 1.4 0.3 4.5 0.3 2.1 0.1 0.1 6.5 GREM2 "CKTSF1B2, DAND3, FLJ21195, Prdc" ENSG00000180875 "Gremlin 2, DAN family BMP antagonist" Q9H772 1 240489573-240612155 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Heparin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 31.4;liver: 26.3" "Cell type enriched" "Detected in many" 9 "Syncytiotrophoblasts: 298.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "fHDF/TERT166: 32.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB009920 Approved "Secreted to blood" NA NA 12000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB009920: AB_2279266" "unprognostic (2.01e-1)" "unprognostic (2.49e-1)" "unprognostic (7.41e-2)" "unprognostic (7.58e-3)" "unprognostic (2.82e-3)" "unprognostic (1.34e-1)" "unprognostic (8.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" "unprognostic (6.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (3.07e-8)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.38e-2)" 0.8 1.7 2.1 9.7 2.9 0.1 3.4 0.1 6.1 0.9 0.0 17.1 10.8 9.6 2.2 17.1 1.4 31.4 0.0 1.3 1.8 2.3 26.3 1.2 0.2 2.1 1.7 6.6 0.2 22.9 2.1 4.0 1.9 2.6 20.1 5.8 4.2 1.8 7.3 3.6 14.9 6.4 1.3 3.2 9.3 0.3 2.8 0.3 0.5 0.7 0.2 3.8 0.5 2.0 0.0 0.0 0.1 0.0 1.9 2.4 0.0 6.1 6.5 0.0 0.0 0.0 0.0 0.0 0.0 32.3 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 2.2 0.0 2.8 1.3 0.0 0.0 3.9 0.5 0.8 0.4 1.0 0.0 0.0 3.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 2.9 0.1 6.1 1.3 1.8 2.1 1.7 1.9 1.3 2.8 2.0 0.2 0.0 0.0 0.3 0.2 4.7 0.0 0.0 0.6 20.8 14.0 0.1 0.6 0.0 0.0 0.0 12.5 7.4 0.6 0.6 0.0 0.0 0.0 2.3 1.2 0.6 1.2 0.0 28.6 0.0 1.7 17.4 0.0 13.7 0.0 0.1 0.7 20.4 1.5 0.0 30.5 0.1 0.0 0.3 6.2 0.2 0.0 0.2 1.8 3.7 0.0 0.4 1.0 1.5 1.2 0.1 0.1 4.5 0.1 0.6 0.0 0.0 0.7 6.7 0.0 0.2 1.4 2.4 2.7 0.6 3.7 298.0 1.6 2.3 0.6 0.1 GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1420.7;Kupffer cells: 892.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9" "Group enriched" "Detected in all" 9 "dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" NA NA 138000000 110000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" 158.9 123.2 61.5 160.4 67.2 478.5 120.7 67.7 97.3 156.7 73.9 189.8 130.9 108.3 134.0 534.0 87.1 157.3 153.0 61.0 69.7 167.4 118.9 309.5 183.2 81.0 71.5 73.8 108.9 87.8 84.4 183.2 87.6 111.7 110.3 12.5 262.9 100.6 60.6 189.7 179.0 91.9 71.8 349.8 127.9 59.4 94.3 67.8 127.7 45.9 107.8 150.0 198.3 97.3 119.3 197.5 52.7 159.5 443.2 231.8 181.2 147.3 447.5 231.6 309.8 86.3 294.0 364.0 299.4 217.6 312.9 185.3 68.6 334.5 75.8 55.8 186.8 38.4 93.8 175.2 245.5 61.6 493.6 332.4 450.5 188.1 106.0 391.2 269.8 64.3 75.1 51.3 148.8 183.1 32.8 172.8 44.3 110.5 334.0 97.7 180.8 433.0 248.2 145.9 54.7 74.7 201.0 92.7 360.9 138.0 209.4 229.0 340.7 437.6 104.6 300.5 97.8 116.3 313.9 122.3 268.1 149.6 124.2 215.1 2057.5 176.5 35.1 1122.4 27.8 174.0 37.1 31.1 1534.2 112.2 27.8 26.5 851.2 30.6 548.1 1331.9 55.4 1613.4 61.5 67.2 67.7 97.3 61.0 69.7 81.0 71.5 87.6 71.8 94.3 97.3 113.0 86.6 83.3 12.7 82.8 112.7 151.1 574.2 97.9 23.6 85.7 69.7 90.7 133.0 332.7 218.8 18.8 429.1 195.7 494.8 9.8 447.7 2.1 103.8 83.8 170.9 124.3 38.7 6.8 307.3 324.1 149.4 83.6 372.5 75.5 90.0 207.8 84.7 1420.7 47.1 6.6 214.6 146.5 892.0 360.8 6.8 60.9 699.2 208.1 20.6 501.6 58.9 20.6 11.1 11.8 285.3 581.7 57.2 65.8 70.7 312.1 120.5 70.0 11.8 85.5 45.4 83.3 25.1 72.2 255.5 96.5 640.0 30.8 89.6 274.5 175.6 GRP ENSG00000134443 "Gastrin releasing peptide" P07492 18 59220158-59230774 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;stomach 1: 12.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 24.4;Early spermatids: 15.5;Ionocytes: 6.1;Late spermatids: 12.2;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.6" "Region enriched" "Detected in all" 4 "midbrain: 26.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BJ hTERT+: 5.1;fHDF/TERT166: 6.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 24.9" "Secreted in other tissues" NA NA 340000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.91e-2)" "unprognostic (1.85e-1)" "unprognostic (2.30e-3)" "unprognostic (3.21e-2)" "unprognostic (7.86e-3)" "unprognostic (3.01e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (1.79e-1)" "unprognostic (5.86e-4)" "unprognostic (2.65e-4)" "unprognostic (9.94e-2)" "unprognostic (6.99e-2)" "unprognostic (5.16e-2)" 0.3 0.2 3.2 0.2 2.6 0.0 2.6 1.3 5.0 0.1 2.8 2.1 0.1 0.3 0.3 0.0 0.0 0.3 0.0 6.1 6.0 0.4 0.0 9.0 0.0 3.0 26.1 0.0 1.2 7.0 3.9 0.0 2.4 2.7 0.1 0.5 0.0 0.1 0.0 0.4 0.7 1.2 2.6 0.3 12.3 2.4 3.5 0.1 6.1 0.0 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.0 0.0 0.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.6 1.3 5.0 6.1 6.0 3.0 26.1 2.4 2.6 3.5 1.6 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.2 0.0 0.0 0.4 24.4 0.1 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 2.0 0.5 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.3 12.2 0.3 0.1 0.0 4.7 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.1 6.6 0.0 0.2 1.2 0.9 0.0 0.0 0.0 0.3 0.0 0.0 4.2 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GUCA2A "GUCA2, STARA" ENSG00000197273 "Guanylate cyclase activator 2A" Q02747 1 42162690-42164745 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "intestine: 927.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 3728.7;Paneth cells: 17085.1;Proximal enterocytes: 12113.5" "Group enriched" "Detected in many" 7 "colorectal cancer: 31.6;urothelial cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 52.1" "Not detected" "Not detected" HPA018215 Enhanced "Secreted to blood" NA NA 18000000 "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA018215: AB_1850443" "unprognostic (7.98e-3)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (9.07e-2)" "unprognostic (1.14e-1)" "unprognostic (8.06e-2)" "unprognostic (2.89e-1)" "unprognostic (3.10e-1)" "unprognostic (9.15e-2)" 0.8 0.1 0.0 3.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 716.9 56.5 0.9 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.4 0.2 1.2 0.7 0.0 0.0 0.1 1.2 0.0 0.2 7.3 0.0 0.1 725.9 0.0 0.0 2.0 0.1 0.0 927.5 17.2 0.0 0.2 0.7 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3728.7 0.0 2.6 0.1 0.0 0.0 0.0 47.7 0.0 0.0 1.1 4.4 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 421.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17085.1 0.0 0.0 0.0 12113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 3.8 0.0 206.6 0.2 GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 143.1" "Cell type enriched" "Detected in some" 7 "Paneth cells: 18841.5" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 1.4;CACO-2: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Secreted to blood" NA NA 77700 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (6.22e-2)" "unprognostic (1.86e-1)" 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 89.4 36.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 5.5 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 23.3 0.0 0.0 0.6 0.0 0.1 143.1 0.6 0.0 0.0 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 1098.8 0.0 0.9 1.0 0.0 0.0 0.0 22.8 0.0 0.0 47.9 0.3 0.0 0.0 0.0 22.3 0.0 0.4 3.1 0.1 0.0 0.0 107.2 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 18841.5 0.0 0.0 0.0 2568.9 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 1.3 0.0 55.3 0.9 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.1" "Group enriched" "Detected in many" 24 "dendritic cells: 739.3;NK-cells: 1543.8;T-cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 15 "gdT-cell: 941.4;MAIT T-cell: 926.2;memory CD4 T-cell: 250.0;memory CD8 T-cell: 922.7;naive CD8 T-cell: 494.1;NK-cell: 718.8" "Group enriched" "Detected in all" 42 "NK-cells: 718.8;T-cells: 941.4" "Cell line enhanced" "Detected in some" "HL-60: 4.0;JURKAT: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054134, HPA076751" Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 5.6 6.0 0.9 16.7 0.9 35.3 7.2 0.9 2.5 7.6 1.2 14.7 29.2 14.7 8.8 4.8 4.6 14.0 4.0 0.8 1.0 3.2 15.2 21.9 68.1 1.6 0.9 4.5 1.0 1.3 1.0 3.1 1.1 3.1 17.8 0.0 7.1 3.0 1.7 1.6 27.6 7.2 1.1 51.1 11.7 2.0 1.1 12.4 2.9 1.3 19.2 13.5 2.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 2.5 3.8 941.4 2.3 926.2 3.4 250.0 922.7 3.1 1.3 48.5 494.1 19.9 718.8 4.0 3.2 33.1 712.7 0.9 0.9 0.9 2.5 0.8 1.0 1.6 0.9 1.1 1.1 1.1 1.1 5.1 3.2 18.1 0.0 12.3 0.4 0.1 0.0 2.8 0.0 2.7 2.4 1.6 5.7 3.1 0.0 0.0 0.4 739.3 1.4 0.0 1.6 0.0 1.7 2.7 2.8 0.0 36.2 0.0 0.0 0.2 7.8 20.4 2.1 7.6 0.0 17.9 2.8 0.3 0.0 0.1 1.5 0.0 25.8 2.6 0.0 0.0 12.3 3.6 0.0 12.6 0.0 1543.8 0.0 0.1 0.0 3.9 0.0 40.8 0.1 2.8 3.3 2.9 0.0 0.0 2.6 2.6 0.0 0.1 1.1 1.4 0.7 709.4 0.0 1.8 0.0 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.2;lymphoid tissue: 37.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2050.2;NK-cells: 1704.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6765.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6765.2" "Cell line enriched" "Detected in some" 6 "HMC-1: 22.0" "CAB000376, HPA003418" Enhanced "Secreted to blood" NA NA 2170 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 8.2 1.7 1.2 17.8 1.3 68.2 2.1 1.2 3.9 1.2 1.4 2.5 2.3 7.1 1.6 3.8 1.5 6.5 1.8 1.2 7.9 1.5 4.1 15.3 37.1 1.5 1.5 0.3 1.0 0.7 0.7 3.3 1.6 1.4 2.2 0.0 2.3 1.4 2.0 0.4 4.4 4.3 1.4 28.9 3.5 0.5 1.8 9.7 1.9 1.5 34.6 18.5 1.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.7 2.8 9.9 3.0 5.3 1338.5 4.0 16.0 7.0 95.2 641.6 6.3 3.1 29.1 607.5 43.1 507.8 6.0 6765.2 2.7 1607.1 1.2 1.3 1.2 3.9 1.2 7.9 1.5 1.5 1.6 1.4 1.8 1.3 4.3 6.4 36.0 0.0 15.9 2.8 0.3 0.0 0.0 0.0 0.9 0.8 1.1 4.3 7.4 0.0 0.0 0.4 2050.2 0.6 0.0 1.6 0.0 0.4 0.5 2.7 0.0 11.8 0.0 0.0 0.1 5.1 9.2 0.5 17.7 0.0 4.2 1.2 0.2 0.0 0.0 0.6 0.0 4.8 9.0 0.2 0.0 27.1 42.7 1.0 11.6 0.0 1704.4 0.0 0.1 0.1 2.3 0.0 86.8 0.2 0.6 3.1 4.4 0.0 0.0 1.3 1.3 0.0 0.1 0.4 4.1 0.3 373.8 0.0 0.6 0.1 GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.9;lymphoid tissue: 25.2" "Group enriched" "Detected in many" 10 "dendritic cells: 575.2;NK-cells: 492.3;T-cells: 302.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 1678.5;memory CD4 T-cell: 490.7;memory CD8 T-cell: 1389.6;naive CD8 T-cell: 1214.0" "Lineage enriched" "Detected in all" 7 "T-cells: 1678.5" "Cell line enhanced" "Detected in single" "U-266/70: 1.0" "Low region specificity" "Detected in many" HPA029200 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favorable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" 3.4 5.2 1.2 3.1 1.3 33.9 4.6 1.3 2.4 2.6 1.6 2.7 2.4 2.0 5.0 3.6 3.5 7.0 2.5 1.1 1.3 1.2 6.7 15.9 25.2 2.0 1.2 2.8 0.8 0.7 2.4 1.6 1.5 1.4 2.5 0.0 7.9 2.1 1.9 0.6 2.8 3.4 1.3 24.4 4.7 0.8 1.4 3.8 1.5 0.6 4.5 7.5 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.2 31.6 3.4 1.7 1678.5 3.6 30.2 7.6 490.7 1389.6 3.3 4.6 155.1 1214.0 18.6 250.8 5.4 44.6 4.5 1436.5 1.2 1.3 1.3 2.4 1.1 1.3 2.0 1.2 1.5 1.3 1.4 1.3 2.9 0.0 4.6 0.0 3.3 1.1 0.1 0.0 0.0 0.0 1.7 1.5 1.4 8.6 0.0 0.0 0.0 0.1 575.2 0.0 0.0 0.1 0.1 0.3 0.3 1.5 0.0 8.6 0.0 0.0 0.0 1.2 1.1 0.4 1.3 0.0 7.5 1.2 0.1 0.0 0.0 0.0 0.0 9.3 3.4 0.2 0.0 4.5 3.6 1.9 3.1 0.0 492.3 0.0 0.1 0.0 0.0 0.0 43.7 0.2 0.0 2.6 0.7 0.0 0.0 1.9 1.3 0.1 0.0 0.4 1.8 0.0 302.2 0.0 0.1 0.1 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 4 "dendritic cells: 136.3;T-cells: 301.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Cell line enriched" "Detected in single" 10 "JURKAT: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.0 3.9 0.1 19.4 0.1 10.5 4.9 0.1 0.4 4.3 0.3 3.4 1.6 4.0 4.5 3.0 2.0 11.6 2.0 0.1 0.2 1.7 10.7 5.9 99.6 0.5 0.2 2.7 1.0 0.8 0.5 0.5 0.3 3.2 4.6 0.0 4.6 1.0 0.2 0.6 7.3 2.2 0.2 30.4 6.5 1.2 0.3 11.9 2.3 0.3 27.8 8.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 1.1 164.3 1.0 741.6 0.5 100.2 457.3 0.5 0.5 4.9 77.4 3.1 505.5 0.9 0.9 7.0 95.5 0.1 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.3 0.2 0.3 0.3 3.8 3.2 7.0 0.0 10.7 1.5 0.1 0.0 1.8 0.0 1.5 1.7 0.1 2.8 0.6 0.0 0.0 0.0 136.3 0.1 0.0 0.0 1.3 0.8 0.4 0.8 0.0 4.4 0.0 0.0 0.0 1.2 4.1 0.8 2.5 0.0 8.6 1.5 0.2 0.0 0.0 0.0 0.0 10.3 2.5 1.2 0.0 6.4 1.8 0.0 5.1 0.0 29.9 0.0 0.1 0.0 0.0 0.0 45.1 0.1 0.2 0.8 0.0 0.0 0.0 1.8 1.7 0.0 0.3 0.2 0.6 0.3 301.9 0.0 0.0 0.1 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 13 "dendritic cells: 385.8;NK-cells: 810.5;T-cells: 243.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.7;HMC-1: 2.1;JURKAT: 3.5;MOLT-4: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 2.2 1.1 0.9 10.0 0.9 21.6 1.1 3.6 2.0 1.4 0.3 1.5 2.1 0.8 0.2 0.8 1.3 1.8 0.8 0.9 0.9 1.0 3.3 5.3 19.2 1.0 0.8 0.7 0.4 0.0 0.9 0.4 1.0 1.3 0.3 0.2 2.8 0.4 0.7 0.8 6.2 0.2 0.7 22.7 3.7 1.8 0.9 8.7 1.6 0.1 3.8 1.5 1.4 1.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.1 0.0 0.4 1.3 0.6 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.1 0.5 0.1 0.3 0.1 9.1 1.4 1.3 583.9 1.7 366.5 0.9 189.2 471.3 1.5 4.0 182.8 379.2 11.9 194.9 2.3 3.6 99.1 227.5 0.9 0.9 3.6 2.0 0.9 0.9 1.0 0.8 1.0 0.7 0.9 1.0 3.4 0.0 0.0 0.3 5.7 3.1 0.1 0.0 0.6 0.5 2.4 2.2 0.1 1.5 0.0 0.0 0.0 0.2 385.8 0.1 0.0 0.4 0.9 0.6 1.5 1.4 0.0 12.0 0.3 0.4 0.4 2.2 13.3 1.1 0.0 0.1 3.6 1.4 0.2 0.0 0.2 0.4 0.0 3.7 4.7 1.6 0.0 5.9 1.8 1.0 8.6 1.6 810.5 0.5 0.3 0.3 0.0 0.0 35.8 0.1 0.0 1.2 0.0 1.4 0.0 1.5 1.2 0.5 1.1 0.9 1.4 0.5 243.6 0.2 0.1 0.1 HABP2 "FSAP, HABP, HGFAL, PHBP" ENSG00000148702 "Hyaluronan binding protein 2" Q14520 10 113550837-113589602 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 437.3" "Group enriched" "Detected in some" 5 "Cholangiocytes: 124.4;Hepatocytes: 221.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 92.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "OE19: 64.7;RPTEC TERT1: 50.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA019518 Uncertain "Secreted to blood" NA NA 20200000000 4400000000 "Cluster 62: Liver - Hemostasis" "Cluster 21: OE19 - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" "HPA019518: AB_1850467" "unprognostic (3.89e-2)" "unprognostic (6.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (5.86e-3)" "unprognostic (1.67e-1)" "unprognostic (9.78e-2)" "unprognostic (5.10e-2)" "unprognostic (4.77e-2)" "unprognostic (9.18e-3)" "unprognostic (2.62e-3)" "unprognostic (2.11e-1)" "unprognostic (3.22e-1)" "unprognostic (9.05e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.9 0.0 0.0 3.1 2.9 1.7 0.0 2.2 36.0 3.8 0.1 0.0 14.2 437.3 0.8 0.0 0.0 0.0 0.0 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.1 12.1 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 64.7 0.0 0.0 0.1 0.0 50.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 2.3 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 124.4 0.0 1.8 0.0 0.0 0.0 0.0 3.9 31.4 0.5 10.8 0.8 0.4 0.0 5.3 1.0 3.9 0.0 0.0 17.9 6.5 0.0 0.0 5.3 221.4 1.0 0.0 0.0 0.2 0.0 5.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 12.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.1 HAMP "HEPC, HFE2B, LEAP-1, LEAP1" ENSG00000105697 "Hepcidin antimicrobial peptide" P81172 19 35280716-35285143 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hormone" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2054.8" "Cell type enriched" "Detected in many" 17 "Hepatocytes: 3227.7" "Group enriched" "Detected in many" 12 "glioma: 6.5;liver cancer: 16.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "myeloid DC: 1.5;plasmacytoid DC: 4.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.6" "Cell line enriched" "Detected in some" 440 "Hep G2: 448.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 1900000 10000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.53e-2)" "unprognostic (5.02e-4)" "unprognostic (2.10e-3)" "unprognostic (4.69e-3)" "unprognostic (5.35e-2)" "unprognostic (2.24e-1)" "unprognostic (3.92e-2)" "unprognostic (9.36e-2)" "unprognostic (2.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.61e-1)" "unprognostic (1.86e-1)" "unprognostic (3.68e-7)" "unprognostic (4.11e-2)" "unprognostic (3.93e-2)" "unprognostic (4.08e-2)" "unprognostic (7.77e-2)" 1.0 1.2 17.7 2.0 17.6 5.4 1.5 17.4 30.4 2.3 20.8 0.8 0.9 0.3 0.6 0.5 2.8 0.6 415.0 17.8 20.2 1.1 2054.8 3.2 4.0 48.0 24.9 3.2 88.0 0.4 5.8 2.3 25.8 2.7 0.0 4.2 1.2 1.3 1.2 1.1 0.5 1.0 21.5 1.1 1.1 0.7 18.7 0.1 0.4 0.2 4.4 1.6 0.2 21.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.7 448.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.7 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.4 0.0 4.6 0.0 0.0 17.7 17.6 17.4 30.4 17.8 20.2 48.0 24.9 25.8 21.5 18.7 21.0 0.8 0.0 0.0 0.0 5.7 0.5 1.5 0.0 0.0 0.0 26.2 8.0 1.7 30.0 0.6 0.0 0.0 0.9 0.6 0.1 0.0 0.4 0.0 1.9 1.0 13.7 0.0 89.7 0.2 99.0 1.2 0.4 10.7 1.8 75.7 0.7 45.3 3227.7 187.9 0.0 0.0 0.7 0.0 63.2 1.2 0.0 0.0 28.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 22.6 0.1 0.0 0.1 4.2 0.0 0.1 0.0 0.6 0.0 0.2 0.6 0.0 0.0 0.0 18.6 0.7 4.3 0.5 0.2 2.2 HAPLN1 CRTL1 ENSG00000145681 "Hyaluronan and proteoglycan link protein 1" P10915 5 83637805-83720855 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 75.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 146.7;Granulosa cells: 43.2;Inhibitory neurons: 35.6;Syncytiotrophoblasts: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "PC-3: 152.4;SuSa: 70.1;TIME: 91.8;U-2 OS: 139.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019105, HPA019482, HPA025238" Enhanced Approved Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA019105: AB_1850496, HPA019482: AB_1850498, HPA025238: " "unprognostic (5.74e-4)" "unprognostic (2.94e-2)" "unprognostic (6.58e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (2.76e-3)" "unprognostic (6.01e-4)" "unprognostic (2.52e-2)" "unprognostic (1.70e-1)" "unprognostic (9.04e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "prognostic unfavorable (4.81e-9)" "unprognostic (6.87e-2)" "unprognostic (2.04e-1)" "unprognostic (8.62e-2)" "unprognostic (3.91e-2)" 0.1 0.0 0.3 0.8 0.7 0.0 0.1 1.1 0.9 0.1 0.0 9.0 7.2 0.6 0.3 2.1 0.0 0.8 3.9 0.6 2.7 0.1 0.0 0.5 0.0 0.9 1.0 0.5 0.5 0.2 0.0 75.0 0.6 0.9 11.1 0.1 0.5 0.0 0.0 0.3 10.8 0.5 0.3 0.2 4.8 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.2 0.0 3.4 0.0 152.4 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 70.1 0.1 0.0 91.8 0.0 139.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 1.1 0.9 0.6 2.7 0.9 1.0 0.6 0.3 0.0 0.3 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.1 0.5 6.9 0.0 0.0 0.5 0.0 10.6 146.7 0.0 0.1 0.0 43.2 0.0 0.0 10.6 0.0 35.6 2.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 23.7 0.1 3.8 0.4 0.0 HAPLN2 BRAL1 ENSG00000132702 "Hyaluronan and proteoglycan link protein 2" Q9GZV7 1 156619331-156625725 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 270.8" "Cell type enriched" "Detected in some" 6 "Oligodendrocytes: 202.1" "Cancer enriched" "Detected in some" 10 "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045765 Enhanced "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA045765: AB_10964781" "unprognostic (3.19e-3)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-1)" "unprognostic (2.44e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-3)" "unprognostic (1.31e-1)" "unprognostic (8.25e-2)" "unprognostic (5.54e-3)" "unprognostic (2.72e-2)" "unprognostic (2.70e-2)" "unprognostic (1.08e-1)" "unprognostic (2.25e-1)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 0.7 0.3 52.0 0.0 147.5 0.0 0.5 179.7 74.3 0.8 16.4 0.5 0.8 2.7 0.0 0.1 2.6 0.0 1.7 51.3 84.9 0.5 0.1 0.3 0.0 270.8 149.6 0.6 0.1 0.2 0.4 0.0 215.0 2.5 0.0 0.1 0.2 0.1 0.7 0.3 0.7 0.0 141.7 0.1 0.3 1.3 132.9 0.0 0.3 0.1 0.0 1.3 1.0 255.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 147.5 179.7 74.3 51.3 84.9 270.8 149.6 215.0 141.7 132.9 255.2 1.5 0.0 0.0 5.2 0.0 0.1 0.1 0.0 0.0 1.7 0.9 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 2.3 0.0 0.0 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 12.5 202.1 0.0 5.0 0.0 0.0 0.2 2.8 0.0 0.0 0.5 32.9 0.9 14.4 0.7 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 966.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 50.9" "Lineage enriched" "Detected in all" 5 "T-cells: 50.9" "Cell line enhanced" "Detected in many" "HDLM-2: 34.7;U-2 OS: 31.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 9: U-2 OS - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA039237: AB_10805357" "unprognostic (1.67e-2)" "unprognostic (1.04e-3)" "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (3.27e-1)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (3.82e-1)" "unprognostic (3.37e-3)" "unprognostic (7.37e-3)" "unprognostic (1.13e-3)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.18e-13)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.12e-1)" 10.3 1.9 2.1 11.5 2.0 3.1 8.6 1.9 2.7 5.1 2.1 3.2 0.6 4.3 0.1 6.1 6.2 2.7 4.6 2.1 2.0 6.1 0.9 9.7 11.7 2.4 2.1 2.7 1.4 0.5 2.2 1.4 2.5 5.7 0.4 4.2 6.0 0.7 3.6 6.2 4.6 2.7 2.3 5.7 3.5 1.0 2.4 2.9 4.6 0.6 3.2 6.9 5.6 2.1 2.0 7.0 1.3 15.4 4.4 4.2 4.7 4.4 1.0 1.6 2.0 4.4 6.4 0.0 11.9 5.4 2.5 1.7 14.7 1.9 0.0 34.7 12.9 4.9 0.3 0.0 0.6 0.0 0.1 1.6 0.8 3.0 0.2 0.2 7.1 0.6 0.1 9.3 0.8 0.2 0.1 0.0 11.2 0.0 0.2 0.0 0.6 11.5 2.9 0.1 0.1 4.2 0.9 0.7 6.1 1.9 0.0 0.6 1.3 10.8 31.2 8.1 0.7 1.1 0.1 0.1 3.8 0.0 9.3 1.4 1.1 0.0 1.2 0.8 5.4 0.2 18.3 7.4 2.2 1.5 18.3 8.6 0.3 10.1 0.2 0.8 50.9 5.9 2.1 2.0 1.9 2.7 2.1 2.0 2.4 2.1 2.5 2.3 2.4 2.1 16.0 0.0 3.4 1.3 4.0 32.0 10.8 13.5 4.6 2.5 47.1 42.4 9.3 1.5 10.4 1.8 10.4 5.8 3.2 0.5 0.0 5.3 0.0 6.3 3.7 29.4 0.0 0.0 1.3 2.0 966.2 8.5 1.5 12.1 1.3 2.5 3.3 0.1 19.3 0.0 0.1 0.9 6.1 0.3 22.0 0.2 0.9 3.0 17.8 2.8 9.7 3.8 3.1 0.5 0.1 9.9 0.1 0.7 0.5 10.4 0.0 0.2 2.7 103.8 13.1 7.2 24.5 0.3 2.1 6.3 24.2 20.4 9.4 0.2 0.5 7.8 HAPLN4 "BRAL2, KIAA1926" ENSG00000187664 "Hyaluronan and proteoglycan link protein 4" Q86UW8 19 19254756-19262804 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 107.1" "Group enriched" "Detected in some" 7 "Excitatory neurons: 16.0;Hepatocytes: 6.7;Inhibitory neurons: 19.9;Proximal enterocytes: 15.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 3.5;NTERA-2: 8.3;SCLC-21H: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055856 Enhanced "Secreted in brain" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055856: AB_2682946" "unprognostic (3.36e-4)" 0.1 1.0 5.8 0.1 3.7 0.2 0.2 18.3 107.1 2.0 0.0 0.2 12.4 0.8 0.1 0.0 0.2 0.2 0.1 10.7 20.0 0.5 14.1 0.1 0.1 46.6 9.7 0.6 0.9 0.0 0.7 0.2 43.2 0.6 0.1 2.3 0.1 0.3 0.0 0.2 15.4 0.2 10.9 0.1 0.3 0.1 33.6 0.0 0.0 0.0 0.0 0.1 0.5 35.6 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 3.5 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 1.0 0.0 0.1 0.0 0.4 0.1 0.7 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 3.7 18.3 107.1 10.7 20.0 46.6 9.7 43.2 10.9 33.6 35.6 0.1 0.0 0.0 2.0 0.1 0.1 0.0 0.0 0.0 0.7 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 0.0 0.0 16.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.4 6.7 0.1 0.0 19.9 0.6 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.0 0.0 0.2 0.0 0.5 1.6 0.0 0.0 0.0 0.0 0.0 15.0 0.2 0.0 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 HBEGF "DTR, DTS, HEGFL" ENSG00000113070 "Heparin binding EGF like growth factor" Q99075 5 140332843-140346603 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 128.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 818.1;Squamous epithelial cells: 281.8;Urothelial cells: 548.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 1.6" "Group enriched" "Detected in many" 6 "dendritic cells: 1.6;monocytes: 2.2" "Cell line enhanced" "Detected in many" "HBF TERT88: 61.2;JURKAT: 81.5;TIME: 68.9;U-698: 93.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053243 Uncertain "Secreted to blood" NA NA 118000 "Cluster 7: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "HPA053243: AB_2682086" "unprognostic (3.64e-1)" "unprognostic (3.05e-1)" "unprognostic (4.31e-2)" "unprognostic (5.09e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (8.44e-3)" "unprognostic (3.51e-2)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (7.09e-4)" "prognostic favorable (6.00e-4)" "unprognostic (2.20e-2)" "unprognostic (6.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.87e-2)" 69.5 11.6 11.6 32.3 13.9 36.4 28.7 13.5 14.4 13.1 11.6 19.7 4.6 12.1 2.3 42.3 14.3 56.6 36.3 11.5 12.9 12.8 9.6 44.9 3.2 14.9 13.7 5.2 6.6 5.6 13.1 16.0 14.1 12.8 15.5 12.1 12.0 4.8 28.0 20.1 14.3 36.6 14.7 6.3 31.4 5.4 13.6 4.8 15.9 20.1 4.6 128.6 18.9 16.7 23.2 1.6 3.4 8.1 1.6 0.6 2.7 21.8 8.5 40.5 33.2 13.0 24.4 0.3 16.9 5.4 14.1 7.1 4.2 37.0 61.2 1.3 3.8 0.5 4.9 1.8 1.2 1.5 1.0 0.9 45.7 44.4 17.8 12.0 20.5 81.5 0.2 3.6 8.7 1.6 2.0 10.8 2.9 9.2 6.0 4.0 13.1 0.7 25.0 3.0 1.2 1.3 6.4 0.8 7.8 22.8 1.4 5.9 68.9 23.1 19.5 7.4 49.5 0.5 1.8 93.6 29.1 11.0 30.3 0.0 0.3 0.0 0.0 2.2 0.0 0.3 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 1.6 0.2 0.0 0.2 11.6 13.9 13.5 14.4 11.5 12.9 14.9 13.7 14.1 14.7 13.6 16.7 186.2 221.2 69.3 1.3 5.7 214.6 818.1 161.9 95.6 2.8 37.9 77.8 80.8 24.3 58.0 11.0 0.0 2.5 5.4 199.2 0.0 37.6 0.5 23.6 22.9 94.7 88.3 0.0 2.1 10.7 1.8 35.2 62.7 74.0 21.5 0.6 22.5 3.4 73.2 5.0 2.9 105.1 18.3 39.7 36.2 0.7 0.3 210.2 32.0 4.7 2.1 7.4 0.0 1.0 8.8 89.5 130.6 0.7 3.1 153.2 181.9 1.0 16.4 1.0 0.0 50.5 33.1 2.0 7.4 281.8 125.2 2.6 12.7 1.0 97.7 548.7 HCRT "OX, PPOX" ENSG00000161610 "Hypocretin neuropeptide precursor" O43612 17 42184060-42185452 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1067 "brain: 384.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Enteroendocrine cells: 3.0;Kupffer cells: 1.6;Oligodendrocyte precursor cells: 2.0;Proximal enterocytes: 1.6" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Region enriched" "Detected in many" 7 "hypothalamus: 384.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "hypothalamus: 93.5" "Region enriched" "Detected in some" 21 "hypothalamus: 25.3" "HPA064801, CAB079778" Enhanced Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 58: T-cells - T-cell receptor" "CAB079778: , HPA064801: " "unprognostic (3.34e-2)" "unprognostic (7.76e-5)" "unprognostic (3.21e-2)" "unprognostic (3.01e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" 0.1 0.0 1.8 0.1 1.9 0.1 0.0 0.6 1.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 384.8 0.0 0.0 0.0 0.0 0.6 3.1 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.1 0.5 0.3 0.2 0.3 0.1 0.6 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.8 1.9 0.6 1.2 0.5 384.8 0.6 3.1 1.7 0.3 52.6 0.6 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.0 1.8 0.0 0.0 1.2 0.3 0.0 0.0 0.0 0.5 0.1 0.1 3.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.7 0.2 0.6 0.0 0.4 0.8 0.0 1.6 1.0 0.2 0.0 0.3 0.0 1.0 0.8 0.1 0.0 2.0 0.3 0.4 0.1 0.0 0.4 0.0 1.6 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.9 0.1 0.9 0.1 HDGF HMG1L2 ENSG00000143321 "Heparin binding growth factor" P51858 1 156742109-156766925 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "DNA-binding, Growth factor, Heparin-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026035, HPA048728, HPA053422" Enhanced Enhanced Nucleoplasm "Secreted to blood" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB026035: , HPA048728: AB_2680503, HPA053422: AB_2682146" "unprognostic (2.80e-1)" "unprognostic (9.63e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (9.06e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (2.43e-8)" "unprognostic (9.80e-3)" "unprognostic (2.34e-2)" "prognostic favorable (9.84e-4)" "unprognostic (2.45e-3)" "unprognostic (3.67e-2)" "unprognostic (1.40e-3)" "unprognostic (8.66e-3)" "unprognostic (2.14e-1)" "unprognostic (2.06e-1)" "unprognostic (3.86e-2)" 96.3 89.7 95.9 72.8 98.8 305.3 90.6 98.4 113.4 91.4 98.0 109.2 130.2 77.6 70.0 186.3 112.8 62.5 119.0 92.8 95.1 135.4 222.3 113.5 64.6 106.3 99.7 86.8 93.2 92.8 67.8 71.8 98.8 81.7 118.1 68.9 96.6 56.8 234.9 155.3 128.4 70.5 100.8 77.2 99.1 42.6 99.6 157.2 90.7 132.5 114.9 106.7 102.7 105.7 491.5 249.1 258.2 125.6 150.0 203.0 296.8 158.4 406.3 366.8 234.4 279.4 500.9 335.5 310.6 325.0 158.6 338.8 408.9 365.0 356.0 276.1 299.9 278.1 339.4 241.2 202.0 411.9 227.4 152.4 335.7 292.8 560.4 278.6 272.4 249.6 387.0 260.4 293.7 369.3 345.5 459.2 472.1 755.4 347.7 384.8 156.9 435.1 401.0 162.6 396.9 432.0 380.4 480.3 199.3 319.8 387.6 621.9 242.4 181.1 286.5 230.3 408.9 364.0 486.0 555.6 238.9 318.4 235.2 6.2 9.9 9.2 6.6 8.8 4.9 5.6 5.6 5.9 11.6 6.6 5.0 4.7 5.6 5.2 10.0 11.9 8.2 6.8 95.9 98.8 98.4 113.4 92.8 95.1 106.3 99.7 98.8 100.8 99.6 105.7 51.9 70.5 99.2 12.1 35.3 147.3 185.1 90.5 76.2 66.7 89.9 66.0 91.0 98.7 75.3 71.7 27.1 44.1 72.4 121.4 80.3 112.2 48.4 144.0 79.2 66.1 124.6 217.8 12.0 132.0 107.3 66.7 62.7 91.8 30.4 67.4 35.0 164.5 52.7 53.8 12.4 104.3 48.8 45.6 89.1 47.0 40.7 71.0 39.2 14.0 57.3 71.4 25.7 5.5 16.1 165.7 59.5 45.9 59.0 281.3 138.2 118.1 126.8 34.9 19.7 70.9 57.8 27.7 28.3 108.6 159.4 54.9 50.5 83.2 114.9 228.6 HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 311.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 23.8;Fibroblasts: 95.8;Hepatic stellate cells: 25.0;Muller glia cells: 36.2;Smooth muscle cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.0" "Cell line enhanced" "Detected in some" "ASC TERT1: 171.6;HHSteC: 135.8;HL-60: 82.4;hTEC/SVTERT24-B: 87.4;Karpas-707: 240.7;U-87 MG: 62.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" NA NA 4110000 14000 "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" 7.9 19.8 1.6 6.3 3.3 12.3 5.2 1.5 7.8 7.2 1.8 4.4 2.6 8.1 3.6 2.9 5.4 16.6 4.7 2.9 3.6 11.8 30.3 19.5 2.2 3.6 2.3 1.8 2.1 2.1 2.4 311.9 4.3 7.2 3.4 14.2 2.4 6.4 0.8 0.9 2.3 7.1 1.8 6.5 3.9 2.4 2.9 1.5 5.6 3.9 1.5 10.4 6.3 3.3 0.0 0.0 0.1 0.0 21.6 171.6 0.1 0.7 33.4 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.1 6.0 0.0 0.0 135.8 82.4 0.4 41.4 0.0 87.4 0.3 0.0 2.2 0.0 0.1 240.7 0.6 0.0 0.0 56.4 0.0 0.0 0.2 0.8 0.0 7.5 0.0 0.0 0.2 9.3 0.0 0.1 0.0 0.2 0.0 3.5 0.4 2.0 0.0 0.1 0.0 0.1 0.0 0.0 62.6 16.9 0.1 94.0 15.2 3.9 0.0 18.7 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 3.2 0.0 17.3 1.0 0.0 4.3 1.6 3.3 1.5 7.8 2.9 3.6 3.6 2.3 4.3 1.8 2.9 3.3 6.2 0.0 4.1 16.3 0.0 1.0 0.2 0.0 1.8 0.2 0.3 0.5 1.3 1.5 0.6 0.0 0.0 5.6 0.0 0.0 0.0 0.0 15.2 1.0 23.8 6.2 0.0 2.1 0.3 0.0 4.9 95.8 0.5 0.9 1.3 0.0 25.0 0.5 18.4 0.0 22.4 0.0 0.0 12.5 1.9 2.3 18.3 14.0 1.8 7.5 10.5 36.2 1.0 0.0 0.1 0.0 0.0 10.9 0.3 0.4 0.0 0.0 0.0 0.7 13.1 0.9 26.2 0.2 0.3 0.3 0.1 12.0 0.6 1.3 0.0 0.4 HGFAC "HGFA, HGFAP" ENSG00000109758 "HGF activator" Q04756 4 3441968-3449486 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "liver: 217.1" "Group enriched" "Detected in some" 5 "Early spermatids: 85.6;Hepatocytes: 72.0;Late spermatids: 165.9" "Cancer enriched" "Detected in some" 22 "liver cancer: 26.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA058279, HPA059076" Enhanced "Secreted to blood" NA NA 7590000 9300000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "HPA058279: AB_2683665, HPA059076: AB_2683898" "unprognostic (2.70e-2)" "unprognostic (8.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-2)" "unprognostic (2.85e-3)" "unprognostic (5.37e-3)" "unprognostic (5.90e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-3)" "unprognostic (5.52e-2)" "prognostic unfavorable (9.31e-4)" "unprognostic (2.87e-1)" "unprognostic (2.24e-1)" "unprognostic (9.49e-2)" "unprognostic (3.74e-4)" 0.0 0.0 1.5 0.0 2.3 0.0 0.1 2.2 2.6 0.5 0.7 0.2 0.0 0.2 0.2 0.0 0.3 0.0 0.1 1.3 0.6 0.6 217.1 0.1 0.0 0.9 0.6 0.1 0.1 0.0 0.7 0.0 0.9 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.1 3.8 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 2.2 2.6 1.3 0.6 0.9 0.6 0.9 0.5 0.8 0.6 0.1 0.0 0.0 1.3 0.2 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.5 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 85.6 0.5 0.2 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.4 0.0 4.4 2.2 72.0 0.0 3.3 3.9 0.0 0.0 3.2 0.0 165.9 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 0.3 0.0 0.0 1.2 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 21.5 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;lung: 16.2" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 175.6;Leydig cells: 136.1;Oligodendrocytes: 413.3;Theca cells: 162.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 322.6;TIME: 376.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" 2.3 2.3 10.4 0.4 25.4 0.8 0.3 10.7 19.6 1.3 0.0 3.2 2.6 1.6 3.8 0.0 0.1 1.1 0.2 17.1 11.0 0.8 6.8 16.2 0.0 20.0 20.2 0.6 2.6 0.0 0.3 0.0 13.6 4.7 3.2 0.9 0.3 2.6 0.4 0.2 3.7 0.1 9.4 0.0 5.9 1.5 18.1 2.7 0.6 1.3 0.0 5.0 0.3 37.3 0.0 0.1 4.9 0.1 0.3 1.9 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 3.0 0.2 0.3 0.0 2.2 0.0 2.0 0.1 0.0 0.1 0.1 0.0 0.0 10.4 7.8 17.2 322.6 29.1 0.1 0.0 4.8 0.0 47.7 0.0 4.4 0.0 2.8 0.4 65.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 376.7 0.4 3.9 0.3 2.5 2.2 0.0 10.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.4 25.4 10.7 19.6 17.1 11.0 20.0 20.2 13.6 9.4 18.1 37.3 0.3 12.8 175.6 3.9 0.4 0.0 0.0 0.5 0.0 42.7 0.0 0.0 1.2 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.5 6.0 0.6 0.0 0.0 17.6 0.4 0.0 38.9 0.0 0.4 16.5 0.1 9.3 0.1 0.1 0.0 13.9 0.0 2.0 0.0 0.4 4.5 136.1 1.3 1.8 1.0 0.0 0.3 0.0 8.5 413.3 0.1 0.0 44.0 0.0 0.0 0.0 0.0 4.4 3.3 0.0 1.7 0.9 0.3 0.5 0.0 0.6 0.0 1.0 162.7 0.0 0.0 HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in some" "Astrocytes: 33.3;Bipolar cells: 10.5;Excitatory neurons: 8.3;Inhibitory neurons: 12.2;Muller glia cells: 13.1;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;fHDF/TERT166: 5.6;SiHa: 3.7;THP-1: 3.9" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 120000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (6.16e-2)" "unprognostic (3.44e-2)" "unprognostic (3.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.75e-2)" "unprognostic (4.70e-3)" "unprognostic (6.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.35e-3)" "unprognostic (8.49e-6)" "unprognostic (2.52e-2)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (7.12e-6)" 1.6 0.3 7.0 1.1 8.7 0.1 0.8 4.1 8.4 1.5 3.0 2.0 0.5 2.5 0.4 0.8 1.3 1.2 1.6 7.2 4.6 0.7 0.6 0.7 1.0 4.9 4.7 1.0 0.2 0.3 0.9 0.6 4.5 1.7 0.3 2.1 0.8 0.9 0.3 0.5 0.9 1.8 4.0 0.9 0.8 0.4 6.3 0.1 0.5 0.4 0.6 1.3 1.1 4.2 0.0 0.2 0.4 0.1 0.1 0.0 1.7 1.6 0.4 0.3 0.1 0.1 0.5 0.1 3.1 5.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.9 0.1 1.2 0.2 0.1 1.4 0.1 0.0 0.1 0.9 0.2 0.0 0.2 1.2 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.6 3.7 0.0 0.0 0.6 0.0 3.9 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 8.7 4.1 8.4 7.2 4.6 4.9 4.7 4.5 4.0 6.3 4.2 1.6 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 10.5 0.3 0.8 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 2.0 1.7 0.0 0.0 8.3 0.0 0.1 2.6 0.0 0.0 0.0 0.9 0.7 0.3 1.9 0.0 12.2 0.0 0.0 2.1 0.7 0.2 0.3 0.3 3.6 6.5 0.0 13.1 0.0 13.0 6.2 0.0 1.4 1.9 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.9 0.9 0.3 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.1 HHIPL2 "FLJ13840, KIAA1822L" ENSG00000143512 "HHIP like 2" Q6UWX4 1 222522258-222548104 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.8;thyroid gland: 2.0" "Group enriched" "Detected in some" 9 "Early spermatids: 16.7;Late spermatids: 25.5;Spermatocytes: 13.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 18.7;Hep G2: 5.7;RH-30: 21.3;SuSa: 7.8;U-87 MG: 10.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059673 Enhanced Uncertain Mitochondria,Cytosol "Secreted in other tissues" No NA "Cluster 1: Thyroid gland - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria Cytosol "HPA059673: AB_2684100" "unprognostic (1.35e-2)" "unprognostic (4.62e-3)" "unprognostic (2.91e-1)" "unprognostic (9.21e-2)" "unprognostic (3.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.74e-3)" "prognostic unfavorable (4.64e-4)" "unprognostic (8.07e-2)" "unprognostic (3.64e-1)" "unprognostic (2.29e-2)" "unprognostic (2.14e-2)" "unprognostic (0.00e+0)" "unprognostic (6.52e-2)" "unprognostic (4.21e-4)" "unprognostic (2.30e-3)" "unprognostic (8.38e-2)" 0.2 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.1 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 2.0 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.1 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 18.7 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.9 5.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.1 0.3 0.0 21.3 0.0 0.2 0.0 0.3 0.1 0.1 0.1 0.0 7.8 0.0 0.0 0.0 1.0 0.3 0.0 0.2 0.0 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 1.8 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 25.5 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 13.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 HHLA1 PLA2L ENSG00000132297 "HERV-H LTR-associating 1" C9JL84 8 132061486-132111159 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 2: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 5: NTERA-2 - Transcription" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (5.15e-2)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HLA-G ENSG00000204632 "Major histocompatibility complex, class I, G" P17693 6 29826967-29831125 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 13.8;placenta: 11.1" "Cell type enriched" "Detected in many" 45 "Extravillous trophoblasts: 1850.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" CAB016158 Enhanced "Secreted to blood" NA NA 32800000 67000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016158: AB_627938" "unprognostic (1.13e-2)" "unprognostic (9.95e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (8.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-3)" "unprognostic (2.51e-1)" "prognostic favorable (3.91e-5)" "unprognostic (6.34e-2)" "unprognostic (8.31e-2)" "unprognostic (1.78e-1)" "unprognostic (1.03e-2)" "unprognostic (6.56e-3)" "unprognostic (1.40e-1)" "unprognostic (1.52e-2)" "unprognostic (3.19e-3)" 0.4 0.3 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.0 0.3 0.3 0.1 0.4 0.0 0.0 0.7 0.4 2.7 0.0 0.0 0.0 0.2 1.2 0.0 13.8 11.1 0.0 0.3 0.0 0.0 0.6 0.0 0.2 0.4 0.7 0.0 0.0 1.3 0.7 2.7 0.0 0.4 0.6 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.4 0.8 0.6 1.0 0.7 0.6 0.9 0.4 0.5 0.5 1.3 2.1 0.8 0.6 0.1 1.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.6 0.0 1.2 22.8 7.3 7.1 1.2 0.0 0.2 0.0 0.8 4.3 1.8 0.0 0.0 10.7 2.7 28.1 0.0 4.5 20.1 0.9 1.3 8.8 17.5 2.7 0.0 5.6 1850.2 5.5 1.5 2.6 0.0 0.7 6.4 1.2 25.5 0.0 0.0 34.3 2.0 8.1 27.3 13.0 2.5 4.8 12.4 0.0 1.4 0.0 3.1 0.0 0.0 24.9 19.9 2.6 0.9 14.3 0.2 0.3 0.6 0.0 0.0 4.8 3.8 5.9 2.8 0.1 35.2 40.5 6.8 1.9 18.2 15.0 HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.3" "Cell type enhanced" "Detected in many" "Adipocytes: 33.8;Endothelial cells: 21.4;Fibroblasts: 22.2;Horizontal cells: 26.9;Microglial cells: 45.0" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 22.3;hTERT-RPE1: 20.1;MCF7: 76.5;SK-MEL-30: 50.2;WM-115: 43.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 9.9" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 9200000 "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" 9.7 1.4 1.3 0.6 1.2 0.0 8.4 0.9 1.1 3.7 1.3 9.0 0.9 1.9 2.5 5.4 1.8 6.5 8.4 0.8 1.1 2.5 7.8 20.3 0.4 1.5 1.9 3.9 0.9 0.9 3.2 4.8 1.5 7.5 2.8 0.6 7.7 1.4 4.8 4.1 3.1 4.3 1.4 8.4 1.7 2.6 1.7 0.8 3.2 7.0 2.4 1.8 3.8 0.9 0.2 0.1 1.6 0.0 4.7 4.7 0.0 0.5 0.9 0.3 0.5 0.0 0.1 1.9 0.2 22.3 1.6 5.0 0.1 0.2 0.1 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 4.7 0.0 5.6 0.4 20.1 2.8 0.0 0.2 0.0 0.0 76.5 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 50.2 4.5 0.1 0.0 0.0 13.7 1.3 0.0 5.1 0.2 0.0 0.3 2.7 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.3 1.2 0.9 1.1 0.8 1.1 1.5 1.9 1.5 1.4 1.7 0.9 33.8 3.2 7.0 0.3 0.0 3.2 0.2 4.9 2.2 1.7 1.2 1.8 2.8 0.0 0.8 0.0 0.0 0.1 0.2 0.3 0.0 0.0 8.3 0.6 1.5 21.4 0.0 0.0 1.1 0.0 0.8 22.2 0.0 0.9 0.0 5.2 7.9 1.9 0.1 26.9 3.8 0.0 0.0 0.3 2.8 2.7 3.7 0.4 5.4 45.0 0.0 0.1 0.0 3.0 1.5 0.0 0.0 2.2 1.2 0.1 0.0 0.2 1.0 0.0 0.0 2.5 7.7 0.5 0.1 0.4 1.7 0.0 0.4 0.1 0.0 0.2 HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265882-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 33.9;intestine: 51.1" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 283.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 7.8;RH-30: 18.0;SCLC-21H: 2.6;SH-SY5Y: 4.1;U-138 MG: 2.9;U-87 MG: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 27000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053903: AB_2682301, HPA070647: AB_2686290" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.69e-1)" "unprognostic (5.53e-4)" "unprognostic (1.05e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-1)" "unprognostic (3.97e-4)" "unprognostic (3.36e-2)" "unprognostic (3.93e-1)" "unprognostic (1.04e-3)" "unprognostic (1.53e-2)" "unprognostic (3.62e-2)" "unprognostic (8.96e-3)" "unprognostic (8.63e-2)" 14.4 1.3 0.3 1.5 0.2 0.0 3.9 0.1 0.7 21.4 0.0 51.1 5.2 33.9 0.1 4.8 10.1 0.7 12.4 0.1 0.9 4.0 1.2 3.8 1.2 2.0 0.7 2.6 0.9 0.1 0.3 0.2 4.0 9.2 1.9 0.0 2.2 2.3 25.0 4.1 21.6 4.2 1.2 0.4 4.9 5.7 1.0 1.2 4.8 6.3 0.2 9.2 12.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.2 0.5 0.0 18.0 0.1 0.0 0.1 2.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.7 0.1 0.9 2.0 0.7 4.0 1.2 1.0 0.4 1.2 3.2 7.5 2.3 0.5 0.9 0.4 0.0 0.0 1.1 0.2 0.3 4.8 0.0 3.7 0.0 0.0 0.1 0.1 22.9 1.9 0.0 17.0 0.0 0.2 5.0 0.0 0.0 1.3 0.0 0.1 24.8 0.0 0.1 7.6 0.1 0.7 2.3 0.4 1.7 5.8 3.6 2.0 0.8 0.8 10.6 0.0 2.3 1.8 1.0 0.0 0.0 0.0 0.5 0.7 0.1 8.3 0.0 0.1 0.8 34.1 1.2 4.0 0.7 0.0 283.7 4.5 0.9 1.1 0.0 0.6 0.3 1.6 2.9 5.5 4.7 HMGB1 "DKFZp686A04236, HMG1, HMG3, SBP-1" ENSG00000189403 "High mobility group box 1" P09429 13 30456704-30617597 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Autophagy, Chemotaxis, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB005873, HPA073663" Supported Supported Nucleoplasm "Secreted to blood" NA NA 2800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB005873: AB_444360, HPA003506: AB_1079070, HPA073663: " "unprognostic (9.56e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-1)" "unprognostic (4.44e-2)" "unprognostic (4.29e-2)" "unprognostic (3.16e-2)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" "unprognostic (1.73e-1)" "unprognostic (2.64e-2)" "unprognostic (2.30e-2)" "unprognostic (4.28e-3)" "unprognostic (5.22e-3)" "unprognostic (4.67e-1)" "unprognostic (9.13e-3)" "unprognostic (1.97e-2)" 312.0 224.3 266.2 355.1 282.2 1021.3 318.2 267.6 362.4 319.0 227.0 327.8 281.9 363.6 270.1 297.0 265.5 227.0 242.2 250.1 282.9 243.7 360.8 242.2 664.8 281.5 273.3 254.9 189.3 226.1 163.3 252.1 286.2 265.9 381.2 174.8 224.5 280.1 388.5 244.2 309.2 319.5 277.7 284.9 269.0 153.9 269.9 900.3 267.4 364.7 738.9 282.7 274.1 308.2 816.7 617.4 1402.5 1054.0 384.5 380.1 551.4 1012.6 547.9 957.3 643.5 983.6 1328.6 1639.3 515.5 924.0 880.6 886.5 1484.7 817.4 1639.6 869.6 622.4 1727.4 455.4 913.5 210.3 2513.6 1009.8 253.4 426.0 713.3 656.6 497.8 1302.2 1350.8 1167.9 571.7 855.6 1508.3 3224.3 2682.1 1184.3 1424.3 683.7 2673.3 1927.8 965.8 908.1 792.8 1264.0 1139.8 928.6 682.0 541.0 672.3 668.5 1857.9 814.7 637.2 921.8 689.7 1197.1 513.9 714.8 3508.3 261.1 1634.0 1369.3 1036.6 503.7 926.1 467.3 410.9 522.1 582.6 532.3 530.7 520.1 590.7 477.4 459.7 631.7 615.4 411.0 512.5 702.6 1072.0 266.2 282.2 267.6 362.4 250.1 282.9 281.5 273.3 286.2 277.7 269.9 308.2 948.9 458.3 496.6 188.4 920.7 791.1 986.7 942.7 752.4 414.3 471.9 630.0 172.5 561.9 561.3 603.2 131.3 998.9 759.9 408.1 766.9 941.3 113.4 611.2 1040.2 766.0 423.0 1808.9 58.5 967.2 1441.4 676.5 486.3 728.3 546.8 772.2 589.0 749.5 728.8 196.9 47.2 675.6 710.1 549.9 884.4 107.2 720.1 694.2 674.1 81.5 578.7 609.9 879.5 99.5 149.3 1212.3 554.8 666.9 1252.9 811.2 506.7 827.5 418.7 252.8 650.8 588.9 1005.9 549.1 1211.0 1045.8 691.9 465.7 797.9 515.7 839.1 867.9 HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2347.2;lymphoid tissue: 939.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 1915.4;Extravillous trophoblasts: 872.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 798.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 2454.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli "Secreted to blood" NA Yes 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB037206: AB_1079071, HPA003506: AB_1079070, HPA053314: AB_2682109, HPA073663: " "unprognostic (2.82e-1)" "unprognostic (8.52e-3)" "unprognostic (2.56e-1)" "unprognostic (8.37e-2)" "unprognostic (8.05e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (7.60e-12)" "unprognostic (1.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.68e-2)" "unprognostic (1.21e-2)" 90.3 31.0 36.3 146.1 38.4 2347.2 89.1 35.4 49.9 79.0 33.0 117.1 93.2 92.3 47.3 115.6 78.8 43.5 85.8 33.2 38.3 74.3 37.8 83.8 390.4 37.5 36.8 118.9 27.2 18.3 35.4 111.0 38.0 46.9 122.2 134.1 59.8 35.2 72.4 75.1 108.7 65.5 36.3 159.5 66.0 136.0 36.1 939.2 56.4 57.0 388.9 68.2 86.1 40.1 498.2 114.6 976.8 444.4 118.2 118.2 375.1 366.3 271.3 386.7 345.7 329.0 673.6 1645.5 79.2 203.0 207.4 190.3 645.0 196.1 601.0 1004.0 303.4 1823.2 308.8 487.8 115.7 1642.8 683.4 114.7 59.2 194.2 439.1 211.5 402.8 866.1 703.9 2282.4 358.9 409.9 2454.9 1513.7 355.4 289.4 199.3 1226.7 499.7 620.4 227.0 208.8 838.6 759.0 365.5 209.6 166.6 340.8 291.1 1173.2 236.0 175.5 513.6 219.0 554.9 734.8 437.1 1869.4 149.1 1178.4 464.4 798.0 135.9 407.0 94.1 57.6 86.2 72.5 137.8 131.1 112.8 57.6 88.4 85.3 316.7 83.0 49.1 43.2 266.4 107.6 36.3 38.4 35.4 49.9 33.2 38.3 37.5 36.8 38.0 36.3 36.1 40.1 167.0 28.9 64.1 5.9 153.2 158.8 141.5 131.8 75.1 48.9 75.3 107.8 229.0 38.6 78.3 55.2 35.5 472.6 222.9 116.5 142.8 25.9 30.4 71.2 71.7 128.0 74.7 1915.4 2.7 16.1 872.5 121.5 63.2 76.5 110.6 210.5 171.7 26.5 210.1 45.4 4.7 191.2 109.9 295.0 142.9 33.1 105.3 233.9 67.6 6.5 241.9 81.8 132.8 1.0 4.8 11.3 75.2 57.6 268.6 114.2 65.4 51.0 149.8 143.5 78.9 71.7 134.4 493.6 400.9 233.6 134.0 128.7 289.5 42.3 284.7 89.0 HMSD "ACC-6, ACC6, C18orf53" ENSG00000221887 "Histocompatibility minor serpin domain containing" "A8MTL9, P0C7T4" 18 63949301-63981774 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8" "Group enriched" "Detected in some" 4 "monocytes: 28.4;Oligodendrocytes: 11.1;Spermatogonia: 9.6" "Cancer enhanced" "Detected in single" "cervical cancer: 1.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 18 "dendritic cells: 1.8" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;GAMG: 8.6;HDLM-2: 18.8;Karpas-707: 7.1" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (5.83e-3)" "unprognostic (1.40e-1)" "unprognostic (1.40e-2)" "unprognostic (5.42e-3)" "unprognostic (6.20e-2)" "unprognostic (1.16e-2)" "unprognostic (4.91e-2)" "unprognostic (3.80e-1)" "unprognostic (1.41e-2)" "unprognostic (5.19e-3)" "unprognostic (8.67e-2)" "unprognostic (1.44e-1)" "unprognostic (7.14e-6)" "unprognostic (1.22e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-3)" "unprognostic (3.55e-1)" 1.3 0.4 2.3 0.8 3.3 0.0 0.3 3.8 6.1 0.2 1.3 0.4 0.1 0.0 0.0 0.9 0.7 0.0 0.9 2.2 2.7 0.5 0.7 1.8 1.6 5.7 3.8 0.2 0.2 0.0 0.1 0.0 5.1 0.2 0.4 0.1 0.2 0.0 0.1 0.7 0.9 0.0 3.6 1.1 0.3 0.6 3.5 0.9 0.7 0.1 1.2 0.1 0.5 6.8 3.3 0.0 0.0 0.0 3.2 7.4 0.0 0.6 2.1 0.3 3.9 0.0 0.8 0.0 0.0 0.9 8.6 3.4 1.3 0.2 2.5 18.8 0.0 0.0 0.1 0.0 0.8 0.0 0.0 4.1 0.0 2.7 0.1 1.0 0.0 0.0 0.0 7.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 3.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 2.3 3.3 3.8 6.1 2.2 2.7 5.7 3.8 5.1 3.6 3.5 6.8 0.1 3.2 0.0 0.3 0.0 1.7 0.2 3.6 0.0 0.1 0.1 0.1 0.3 0.0 0.9 0.0 0.0 0.4 2.9 0.0 0.0 0.5 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.5 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 2.0 0.0 2.7 0.4 0.3 0.5 0.0 0.0 28.4 0.9 0.0 0.5 11.1 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.4 1.5 9.6 0.9 0.1 0.1 0.2 0.1 0.6 0.1 HP ENSG00000257017 Haptoglobin P00738 16 72054505-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "liver: 61113.6" "Cell type enriched" "Detected in many" 43 "Hepatocytes: 59512.7" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Region enhanced" "Detected in all" "medulla oblongata: 29.7" "Group enriched" "Detected in many" 5 "classical monocyte: 49.3;eosinophil: 80.2" "Group enriched" "Detected in many" 7 "granulocytes: 80.2;monocytes: 49.3" "Group enriched" "Detected in some" 5 "Hep G2: 232.2;HSkMC: 121.4" "CAB003787, HPA047750, HPA066795" Enhanced Approved Vesicles "Secreted to blood" NA NA 998000000000 100000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB003787: , HPA047750: AB_2680146, HPA066795: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavorable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" 673.1 11.4 1.3 26.9 1.7 231.5 34.2 1.4 2.9 71.9 3.6 3.6 1.5 3.5 2.9 5.3 74.6 1.3 146.7 1.4 1.4 19.8 61113.6 91.3 1.7 29.7 2.0 9.9 7.6 0.2 49.9 2.5 3.7 7.3 0.6 0.7 6.1 0.2 5.0 3.4 4.4 4.5 2.3 72.0 6.2 2.1 8.3 2.7 6.3 0.4 3.0 3.8 3.3 5.9 0.0 0.0 0.0 0.0 6.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 8.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 11.2 0.2 232.2 0.3 33.3 6.2 121.4 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 2.0 0.4 2.6 0.0 0.0 1.1 23.6 0.0 0.0 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 6.8 5.1 0.0 0.8 0.0 0.0 3.9 0.0 14.1 0.0 12.7 0.0 6.2 49.3 80.2 0.0 2.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 14.2 0.0 2.1 0.0 0.0 15.2 1.3 1.7 1.4 2.9 1.4 1.4 29.7 2.0 3.7 2.3 8.3 5.9 0.4 19.2 228.7 1.6 96.1 0.1 0.7 1.9 0.0 0.4 0.4 0.3 66.6 1085.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 56.7 0.0 1128.3 0.0 10.4 0.1 45.5 0.0 1.3 3.8 0.4 1038.7 59512.7 2.3 0.0 0.0 0.2 4.1 1381.4 0.0 0.5 10.2 7.8 1.8 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 1.5 7.5 0.2 0.0 2.6 1.8 0.0 0.0 0.1 0.3 0.1 90.3 0.0 0.3 0.1 HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 811.9" "Group enriched" "Detected in some" 14 "Hepatocytes: 503.0;Smooth muscle cells: 128.8" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 50.6" HPA047750 Supported Approved Vesicles "Secreted to blood" NA NA 49000000000 55000000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA047750: AB_2680146" "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" 5.5 0.5 14.1 0.2 15.3 0.1 2.0 13.9 16.7 1.2 11.3 1.2 0.6 0.3 0.4 0.3 1.3 0.7 137.2 13.7 14.3 4.0 811.9 1.5 0.7 14.4 14.3 2.0 0.6 0.0 0.3 0.0 13.6 1.6 0.1 0.8 0.3 0.3 1.7 0.6 1.1 0.1 12.8 0.3 1.7 1.9 15.2 0.2 1.1 0.2 0.1 0.4 1.9 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.6 2.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.1 0.0 0.6 0.6 0.0 14.1 15.3 13.9 16.7 13.7 14.3 14.4 14.3 13.6 12.8 15.2 13.1 0.0 0.0 7.5 2.3 0.4 0.1 0.0 0.9 0.0 0.1 0.0 0.0 22.4 12.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.8 0.0 5.3 0.2 0.2 0.0 2.6 0.0 0.0 0.0 1.1 10.8 503.0 0.0 0.0 0.2 0.0 2.0 12.8 0.0 2.8 9.9 0.0 0.0 0.0 0.0 4.9 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.0 0.0 13.0 0.2 0.1 0.0 6.1 128.8 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HPSE2 "HPA2, HPR2, UFS" ENSG00000172987 "Heparanase 2 (inactive)" Q8WWQ2 10 98457077-99235862 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.6;cervix: 36.7;vagina: 27.6" "Cell type enriched" "Detected in some" 9 "Astrocytes: 900.7" "Cancer enhanced" "Detected in some" "prostate cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "BJ hTERT+: 10.2;HEL: 20.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044603 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA044603: AB_10794051" "unprognostic (2.44e-1)" "unprognostic (4.28e-3)" "unprognostic (4.83e-3)" "unprognostic (6.00e-2)" "unprognostic (1.15e-1)" "unprognostic (1.59e-1)" "unprognostic (3.05e-2)" "unprognostic (1.82e-2)" "unprognostic (4.03e-2)" "unprognostic (7.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-4)" "unprognostic (5.79e-2)" "unprognostic (2.51e-1)" "unprognostic (9.39e-3)" "unprognostic (6.13e-3)" 2.0 0.0 9.9 2.0 20.9 0.0 5.2 15.4 7.6 36.7 3.6 2.9 2.7 4.5 0.0 14.3 1.8 1.4 0.1 5.8 21.1 3.5 0.0 2.2 0.0 23.2 29.6 0.2 0.0 0.0 0.3 1.5 21.5 11.1 3.0 0.0 2.4 4.2 0.3 3.2 5.2 1.7 16.5 0.0 4.6 2.7 28.5 0.1 0.1 3.0 0.4 18.3 27.6 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 10.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.9 20.9 15.4 7.6 5.8 21.1 23.2 29.6 21.5 16.5 28.5 11.9 0.3 0.0 0.0 900.7 0.0 0.0 4.8 0.0 0.0 0.0 0.2 0.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.4 24.8 0.3 0.0 0.0 6.4 0.0 0.0 4.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 97.3 0.2 0.0 0.0 0.0 48.6 0.3 0.0 0.0 40.3 0.0 0.0 0.0 16.6 4.6 0.0 0.0 0.4 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.9 1.9 11.5 2.1 0.0 0.1 0.0 0.2 0.8 0.0 0.7 HPX ENSG00000110169 Hemopexin P02790 11 6431049-6442617 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 908 "liver: 5440.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 6095.8" "Cancer enriched" "Detected in many" 79 "liver cancer: 571.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "Hep G2: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016725, HPA065318, HPA068847" Approved "Secreted to blood" NA NA 425000000000 190000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016725: , HPA065318: , HPA068847: " "unprognostic (3.39e-2)" "unprognostic (9.26e-2)" "unprognostic (3.88e-1)" "unprognostic (6.19e-4)" "unprognostic (2.05e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.26e-4)" "unprognostic (6.33e-2)" "unprognostic (5.67e-3)" "unprognostic (3.88e-1)" "unprognostic (5.08e-3)" "unprognostic (2.78e-2)" "unprognostic (5.82e-12)" "unprognostic (2.01e-1)" "unprognostic (4.48e-1)" "unprognostic (1.84e-2)" "unprognostic (2.14e-2)" 1.1 0.8 0.8 0.1 0.7 0.1 5.9 1.0 1.0 1.6 0.6 1.2 0.4 1.0 0.2 0.5 1.6 0.3 0.9 0.7 0.7 1.4 5440.6 1.2 0.3 0.7 0.7 1.6 5.5 0.1 1.2 0.3 0.7 2.4 0.6 1.7 1.1 0.6 0.3 1.6 1.1 0.3 0.6 3.8 0.9 1.1 0.8 0.1 0.9 0.0 0.1 1.1 1.2 0.7 0.2 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.3 1.3 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.6 0.2 21.3 0.0 3.0 0.0 0.8 0.6 0.1 0.0 0.5 0.1 0.2 0.4 0.1 0.1 0.4 0.0 0.0 0.3 0.9 0.0 0.1 1.3 0.2 0.0 0.1 0.2 0.0 1.0 3.0 0.2 0.2 1.1 0.0 0.5 0.3 0.2 1.0 0.1 0.4 0.2 0.9 0.2 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 1.0 1.0 0.7 0.7 0.7 0.7 0.7 0.6 0.8 0.7 0.5 3.2 0.5 0.3 15.1 0.6 0.2 0.2 0.0 1.5 19.1 7.7 0.7 80.1 0.2 0.0 2.1 0.1 0.1 0.6 0.0 0.1 2.3 0.2 0.3 6.2 0.0 157.7 0.7 0.6 0.1 0.4 0.0 1.2 0.0 1.1 132.8 6095.8 0.2 0.0 0.8 0.7 0.0 155.3 0.2 2.9 0.3 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.7 0.2 0.0 1.0 2.1 0.0 0.4 0.5 0.6 0.5 0.0 0.3 0.0 11.3 0.2 0.5 0.3 HRG "HPRG, HRGP" ENSG00000113905 "Histidine rich glycoprotein" P04196 3 186660216-186678234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Blood coagulation, Chemotaxis, Fibrinolysis, Hemostasis" Heparin-binding "Disease variant, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "liver: 5433.2" "Cell type enriched" "Detected in some" 29 "Hepatocytes: 479.7" "Cancer enriched" "Detected in some" 262 "liver cancer: 406.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 2.7;RH-30: 3.0;SiHa: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050269, HPA054598" Supported "Secreted to blood" NA NA 120000000000 28000000000 "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 15: Hepatocytes - Hemostasis" "HPA050269: AB_2681068, HPA054598: AB_2682539" "unprognostic (2.67e-1)" "unprognostic (1.74e-2)" "unprognostic (7.58e-5)" "prognostic favorable (9.64e-5)" "unprognostic (1.44e-1)" "unprognostic (2.98e-3)" "unprognostic (2.22e-1)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 31.4 5433.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 3.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.6 0.0 10.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 479.7 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 19.0" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" 3.9 9.8 46.6 1.3 46.7 2.6 5.1 32.0 58.2 5.5 34.0 8.4 1.6 5.4 5.1 3.7 6.7 3.0 5.9 46.1 41.8 12.4 5.4 4.4 1.4 38.4 36.5 6.7 7.0 7.3 21.2 1.5 37.2 6.1 1.0 6.3 5.8 4.1 10.9 9.3 3.4 1.6 32.9 3.2 6.3 8.1 42.4 1.6 8.6 3.3 1.0 6.0 4.3 39.1 3.6 3.0 11.3 2.1 5.0 5.7 2.2 2.7 4.4 1.1 4.8 1.3 3.3 0.8 5.9 2.2 0.9 1.7 1.4 1.8 1.0 3.2 3.6 2.3 3.0 2.2 3.6 0.9 7.9 5.5 3.9 1.6 1.6 10.4 1.8 5.1 2.4 2.9 4.6 0.3 2.1 2.1 3.0 14.2 4.1 3.6 0.5 3.1 9.5 0.8 3.2 19.0 0.5 1.6 12.8 3.8 2.6 0.7 3.2 2.7 5.0 4.9 2.2 7.6 2.8 0.9 7.7 1.2 2.4 1.5 1.0 0.5 0.6 2.7 0.6 0.5 1.4 1.6 1.0 1.1 1.8 1.7 1.9 0.7 1.8 2.2 0.4 0.9 46.6 46.7 32.0 58.2 46.1 41.8 38.4 36.5 37.2 32.9 42.4 39.1 8.2 0.0 2.6 13.7 2.6 8.2 8.6 12.9 9.6 11.3 23.7 23.1 2.3 10.0 8.6 23.9 14.6 4.7 3.0 4.5 15.6 12.4 9.5 21.8 6.0 6.1 25.7 1.3 24.7 4.7 6.5 8.1 4.6 5.4 10.2 12.4 8.9 4.1 5.1 8.4 20.4 4.6 12.2 2.8 6.0 13.9 7.2 2.4 5.4 1.9 3.1 30.5 1.0 14.1 4.6 4.8 4.3 12.8 0.9 8.4 4.1 33.3 31.2 12.9 0.0 8.1 9.5 10.8 12.7 4.8 10.2 2.9 3.1 16.6 3.7 9.7 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HTN1 HIS1 ENSG00000126550 "Histatin 1" P15515 4 70050438-70058848 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2602 "salivary gland: 48372.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077315 Approved "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: Alveolar cells - Smell perception" "HPA077315: " "unprognostic (2.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 18.5 0.0 0.0 5.5 0.0 0.0 0.0 0.0 48372.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 HTN3 HIS2 ENSG00000205649 "Histatin 3" P15516 4 70028455-70036538 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1102 "salivary gland: 136053.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "melanoma: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;HL-60: 1.7" CAB073541 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB073541: " 0.0 0.1 0.7 0.3 1.3 18.9 0.1 2.8 2.3 0.0 0.0 2.4 0.3 0.2 0.4 0.2 0.1 0.1 26.2 0.9 0.0 0.1 0.1 0.2 0.3 0.1 0.0 26.0 123.4 0.1 1.8 13.1 0.2 0.2 3.0 0.7 136053.4 0.1 0.1 10.0 0.1 0.1 0.0 0.2 0.3 0.5 0.1 0.0 0.2 0.0 0.1 0.1 0.0 1.5 0.4 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.6 0.2 0.0 0.2 0.2 0.0 0.1 0.0 1.6 0.2 0.1 0.3 0.1 0.0 1.7 1.1 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.1 0.7 0.2 0.2 0.4 0.9 0.4 0.1 0.4 1.0 0.2 0.1 0.1 0.1 0.6 0.4 0.4 0.2 0.3 0.3 0.7 0.4 0.0 0.3 0.6 0.4 0.3 0.5 0.9 0.2 0.3 0.5 0.8 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.7 1.3 2.8 2.3 0.9 0.0 0.1 0.0 0.2 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 158.8;Leydig cells: 43.5;Peritubular cells: 42.9;Skeletal myocytes: 99.0;Theca cells: 25.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 182.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" 68.0 6.0 0.9 8.7 1.3 13.4 50.4 0.9 1.3 35.4 5.0 33.9 8.7 42.4 10.6 15.1 26.2 35.5 194.9 0.9 1.0 6.2 3.2 38.0 1.2 1.0 1.0 93.0 6.8 0.4 15.7 20.4 1.0 26.3 4.8 0.1 22.8 6.7 32.1 28.1 16.9 11.8 1.0 2.9 21.9 4.3 1.7 2.2 26.0 12.9 0.7 62.4 32.6 0.7 0.0 1.0 1.4 0.0 5.8 10.8 0.3 2.4 0.2 2.8 0.6 0.1 0.1 0.0 13.6 6.4 1.4 0.1 1.2 0.0 0.9 0.0 2.3 1.3 13.9 0.0 6.1 0.0 0.6 1.2 0.0 4.2 0.0 1.7 9.8 0.0 0.3 0.0 10.2 0.0 0.2 36.5 6.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 15.8 0.3 26.4 0.5 0.2 28.8 0.1 1.1 8.1 1.4 4.7 182.1 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.3 0.9 1.3 0.9 1.0 1.0 1.0 1.0 1.0 1.7 0.7 12.6 0.0 0.0 0.0 0.0 5.2 0.5 0.0 0.6 0.0 0.5 0.9 16.5 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 1.2 0.3 8.1 5.3 0.0 0.0 0.0 0.0 4.2 158.8 0.5 0.3 0.0 6.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 8.6 1.4 43.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.4 0.4 0.0 0.1 0.0 0.0 0.0 99.0 10.6 0.4 0.7 0.6 5.3 1.4 0.9 25.2 0.0 0.2 HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974228-38988663 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 67.0" "Cell type enriched" "Detected in some" 10 "Extravillous trophoblasts: 444.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "BEWO: 233.6" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" NA NA 23000 "Cluster 17: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA045402: AB_2679316" "unprognostic (1.20e-1)" "unprognostic (5.83e-4)" "unprognostic (8.02e-2)" "unprognostic (2.13e-2)" "unprognostic (8.20e-2)" "unprognostic (2.42e-2)" "unprognostic (1.80e-1)" "unprognostic (7.40e-3)" "unprognostic (1.40e-1)" "unprognostic (5.14e-4)" "unprognostic (1.01e-1)" "unprognostic (8.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.58e-1)" "unprognostic (5.19e-3)" "unprognostic (2.39e-3)" "unprognostic (1.19e-3)" 0.8 0.5 0.8 0.8 1.2 7.2 1.2 3.5 5.0 0.9 0.0 0.5 0.3 0.9 0.9 0.1 0.3 0.5 0.3 1.3 0.9 0.4 0.5 2.0 2.5 0.6 0.5 0.6 0.8 0.5 0.1 67.0 0.6 0.6 0.7 1.8 0.3 1.1 1.0 0.8 0.4 0.7 0.1 1.2 0.4 0.9 1.4 0.5 0.5 0.1 1.7 0.4 0.1 2.0 0.4 0.3 0.2 0.4 0.8 0.4 233.6 0.6 0.4 0.3 0.4 0.4 0.5 0.5 0.2 0.2 0.4 0.4 0.2 0.2 0.1 0.2 0.4 0.4 0.7 0.3 0.2 0.6 0.6 0.7 0.2 0.2 0.5 0.3 0.2 0.2 0.4 1.3 0.2 0.5 0.4 0.3 0.3 0.1 0.2 0.2 0.2 0.4 0.2 0.7 0.4 0.6 0.5 0.3 0.1 9.6 0.5 0.7 0.0 0.7 0.5 0.3 0.3 0.5 0.2 0.2 0.2 0.7 0.2 0.3 0.1 0.4 0.2 0.1 0.3 0.2 0.2 0.2 0.1 0.5 0.2 0.2 0.5 0.2 0.2 0.5 0.3 0.0 0.8 1.2 3.5 5.0 1.3 0.9 0.6 0.5 0.6 0.1 1.4 2.0 0.1 0.0 0.0 0.0 1.0 0.1 1.7 0.1 1.2 0.5 0.1 0.3 0.7 0.0 0.0 0.0 2.1 2.8 1.1 0.1 0.0 0.0 0.1 0.2 0.7 0.3 0.0 0.0 0.4 0.0 444.0 1.2 0.0 0.5 0.0 0.7 1.4 0.0 11.6 1.7 0.2 0.0 0.0 0.6 0.3 0.0 0.0 3.8 1.8 1.0 0.0 0.4 1.0 1.5 0.2 0.3 0.0 0.0 0.5 1.5 0.0 0.2 0.1 0.2 0.0 3.5 0.2 0.0 0.1 0.0 0.1 40.4 0.7 0.2 0.2 1.1 HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 201.6;lymphoid tissue: 95.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Hepatic stellate cells: 33.2;Hepatocytes: 137.1;Proximal tubular cells: 58.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 100.9;SK-BR-3: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 590000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 11.4 21.5 5.0 2.8 4.5 0.3 9.2 6.4 6.3 10.8 18.3 6.8 3.4 8.2 0.8 5.5 7.3 13.2 68.2 4.5 4.0 49.4 201.6 30.7 1.8 5.4 4.8 3.0 9.4 19.9 3.3 2.4 5.6 4.6 2.9 3.1 7.3 2.9 15.0 21.1 6.0 5.9 3.5 95.1 19.4 1.7 5.8 0.8 8.3 19.0 1.2 4.8 12.3 4.7 2.9 1.8 0.4 0.9 0.6 0.7 0.5 0.1 0.3 0.1 0.4 11.4 3.1 0.0 0.8 0.6 0.6 6.6 0.2 0.4 0.0 0.1 0.0 0.3 8.6 100.9 4.4 0.7 0.7 3.9 13.8 0.1 0.4 0.8 2.9 0.3 0.3 0.5 0.4 0.6 0.1 0.3 0.6 7.1 0.6 0.0 0.2 0.3 5.9 0.4 0.2 2.1 0.2 28.0 0.3 2.4 2.0 0.3 1.9 0.6 0.6 0.6 0.3 0.2 0.3 0.4 0.4 0.6 0.3 1.3 0.4 1.5 0.3 0.1 0.8 0.4 0.3 0.4 0.2 0.5 0.6 0.4 3.1 0.3 0.3 0.5 0.4 0.1 5.0 4.5 6.4 6.3 4.5 4.0 5.4 4.8 5.6 3.5 5.8 4.7 18.1 19.2 18.5 1.6 0.3 2.9 0.4 3.3 0.0 1.0 0.3 0.1 20.8 30.0 2.0 11.0 4.2 0.1 0.0 2.5 23.5 16.5 8.2 0.2 0.9 25.8 1.8 2.7 3.1 14.4 0.1 3.3 19.4 0.2 0.0 0.6 33.2 137.1 0.1 0.0 3.1 1.4 0.0 4.4 0.9 7.7 2.1 0.9 0.0 7.5 0.0 0.4 0.0 1.5 1.6 12.1 0.3 1.2 0.0 0.2 0.4 58.2 0.9 0.5 6.6 1.2 4.3 0.4 1.1 0.9 3.1 0.7 0.9 7.4 0.9 1.7 HYAL3 "LUCA-3, LUCA14, Minna14" ENSG00000186792 "Hyaluronidase 3" O43820 3 50292831-50299405 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.4" "Group enriched" "Detected in many" 17 "Early spermatids: 79.7;Late spermatids: 268.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 33.2;eosinophil: 54.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 54.6" "Cell line enhanced" "Detected in all" "HEL: 58.8;HMC-1: 101.1;THP-1: 107.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA049402 Uncertain "Secreted to blood" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA049402: AB_2680746" "unprognostic (1.21e-3)" "unprognostic (2.55e-2)" "unprognostic (5.45e-2)" "unprognostic (8.19e-2)" "unprognostic (3.07e-1)" "unprognostic (1.65e-2)" "unprognostic (7.98e-3)" "unprognostic (7.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" "unprognostic (5.40e-2)" "unprognostic (5.71e-2)" "unprognostic (2.61e-1)" "unprognostic (8.09e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.12e-5)" 2.1 2.8 5.1 1.3 5.4 36.4 1.8 6.7 8.3 2.0 2.9 1.9 1.7 1.6 1.1 3.9 1.6 1.8 1.8 5.1 4.0 2.6 5.1 2.1 1.2 7.4 4.0 1.5 1.9 0.9 1.9 1.5 7.3 3.2 1.0 1.1 3.5 2.4 1.0 2.1 1.8 2.2 3.9 1.7 4.5 13.9 5.4 1.6 1.7 0.9 1.6 1.8 2.7 5.8 6.0 6.9 3.8 4.3 7.6 3.9 2.3 6.5 5.8 8.0 6.1 9.3 6.2 5.2 3.1 7.5 12.4 6.5 7.0 15.2 3.0 12.3 3.6 58.8 18.8 7.6 5.5 6.4 101.1 8.1 11.5 8.1 5.2 5.8 8.4 5.8 4.6 6.3 3.8 3.6 2.4 37.4 2.9 7.0 17.2 2.6 5.1 9.5 9.5 2.6 4.7 5.4 9.6 7.5 5.1 4.4 4.9 107.2 11.1 6.8 4.9 22.2 3.8 3.0 7.0 4.4 6.0 22.5 5.8 33.2 4.1 54.6 1.3 2.3 2.2 1.6 4.1 1.9 8.2 2.9 1.1 1.5 1.4 2.1 1.4 2.0 2.6 2.4 5.1 5.4 6.7 8.3 5.1 4.0 7.4 4.0 7.3 3.9 5.4 5.8 2.5 3.2 1.1 0.3 0.8 3.1 2.8 8.1 2.8 1.5 2.2 2.8 0.4 1.5 5.0 3.7 4.2 2.8 0.2 0.8 9.8 5.6 79.7 2.0 1.6 3.5 4.2 9.2 2.4 0.7 5.3 1.2 4.1 2.1 7.0 1.1 7.1 2.1 2.1 5.0 1.6 1.9 6.1 1.9 4.4 268.2 1.8 2.0 3.6 1.0 5.9 1.5 0.0 0.5 0.3 3.6 0.4 2.6 1.9 2.2 0.5 2.7 1.8 0.8 6.6 1.2 1.8 4.3 4.6 3.7 3.7 3.0 2.2 1.6 1.8 3.5 IAPP "AMYLIN, DAP, IAP" ENSG00000121351 "Islet amyloid polypeptide" P10997 12 21354959-21379980 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "pancreas: 166.7" "Group enriched" "Detected in some" 5 "Early spermatids: 44.5;Pancreatic endocrine cells: 15.2" "Cancer enriched" "Detected in single" 76 "pancreatic cancer: 21.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000352, HPA053194" Enhanced Approved Vesicles "Secreted to blood" NA NA 11900 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000352: AB_2121635, HPA053194: AB_2682076" "unprognostic (5.52e-3)" "unprognostic (1.00e-1)" "unprognostic (4.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.91e-1)" 0.5 0.0 0.1 0.0 0.2 1.0 0.0 0.5 0.3 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 2.3 0.0 0.2 0.1 0.5 0.0 166.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 3.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.3 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.5 0.3 0.1 0.2 0.1 0.5 0.2 0.0 0.8 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 44.5 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.9 0.3 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 1.5 0.3 0.3 0.2 0.0 0.4 0.3 0.3 0.1 0.0 0.8 IBSP "BSP, BSP-II, SP-II" ENSG00000029559 "Integrin binding sialoprotein" P21815 4 87799554-87812435 "Cancer-related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;pituitary gland: 2.0" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 5.8" "Group enriched" "Detected in many" 4 "breast cancer: 3.8;glioma: 12.2" "Region enhanced" "Detected in single" "thalamus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-138 MG: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.53e-2)" "unprognostic (3.55e-2)" "unprognostic (1.49e-2)" "unprognostic (3.93e-1)" "unprognostic (3.75e-2)" "unprognostic (9.48e-3)" "unprognostic (1.03e-3)" "unprognostic (4.07e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-11)" "unprognostic (6.20e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-3)" "unprognostic (2.11e-1)" 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 2.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.5 0.7 0.7 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" NA NA 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 6.7 10.1 3.4 2.8 3.6 3.5 6.1 3.7 4.2 8.1 5.9 8.6 3.3 7.4 9.7 9.8 6.5 2.9 11.7 3.4 3.7 5.9 11.4 5.9 3.4 3.8 3.7 5.4 12.3 9.5 4.7 2.7 3.9 9.1 3.8 10.3 7.8 4.2 28.8 36.4 6.8 3.7 3.6 6.3 8.2 25.8 3.6 2.4 6.7 9.7 4.1 8.9 7.9 3.8 12.1 22.9 6.2 15.1 10.5 5.8 8.5 10.4 13.3 6.1 5.2 19.4 9.5 12.5 16.4 14.3 7.2 16.3 14.6 10.0 3.9 14.7 8.8 5.1 13.7 25.9 11.5 14.9 6.5 5.4 6.6 9.1 14.0 7.8 8.6 3.3 10.0 8.1 5.4 18.0 6.6 8.8 10.2 10.4 5.2 10.2 10.8 9.0 10.9 19.3 2.2 5.6 14.3 6.4 6.7 6.8 12.6 6.3 15.3 4.4 8.2 5.0 10.4 11.2 12.2 14.5 6.9 10.9 4.4 0.3 3.5 1.4 2.0 4.2 2.2 2.9 2.6 2.9 4.6 2.1 1.9 2.0 0.0 3.7 5.9 1.3 3.9 2.3 3.4 3.6 3.7 4.2 3.4 3.7 3.8 3.7 3.9 3.6 3.6 3.8 12.9 9.6 14.1 20.9 11.1 5.2 6.1 10.5 5.2 15.0 8.7 4.3 45.7 7.2 10.6 7.3 47.9 11.2 10.0 14.0 1.9 14.0 46.4 14.9 19.3 10.8 10.8 19.6 43.3 20.2 5.7 9.1 22.4 16.5 1.3 9.9 11.7 24.1 11.9 6.7 42.6 12.7 18.3 16.6 5.4 12.0 6.5 12.5 8.8 23.4 7.8 7.8 4.1 20.6 24.0 16.5 5.7 10.1 24.2 12.2 9.0 10.7 23.3 26.9 6.6 7.6 13.2 51.5 11.0 19.6 16.3 3.8 8.5 9.8 9.8 9.6 IFI35 IFP35 ENSG00000068079 "Interferon induced protein 35" P80217 17 43006740-43014456 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 122.4;Paneth cells: 116.7;Proximal enterocytes: 128.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 204.5;BJ hTERT+ SV40 Large T+ RasG12V: 299.2;GAMG: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045946, HPA075580" Approved Supported "Nucleoplasm,Intermediate filaments,Cytosol" "Secreted to blood" NA NA 120000 "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "Intermediate filaments" "HPA045946: AB_2679509, HPA075580: " "prognostic favorable (1.41e-4)" "unprognostic (1.14e-2)" "unprognostic (1.82e-1)" "unprognostic (2.16e-1)" "unprognostic (1.32e-1)" "unprognostic (3.26e-1)" "unprognostic (3.90e-3)" "unprognostic (1.14e-1)" "unprognostic (6.92e-2)" "unprognostic (9.78e-3)" "unprognostic (6.51e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (4.03e-5)" "unprognostic (3.55e-1)" "unprognostic (3.62e-2)" "unprognostic (1.34e-2)" "unprognostic (1.49e-1)" 27.5 41.3 15.4 27.2 16.4 24.9 24.2 15.6 18.2 18.4 16.2 27.4 24.6 17.4 11.7 10.2 20.8 20.1 20.9 14.9 16.7 29.7 30.6 25.6 26.4 20.2 16.6 23.8 13.6 10.5 14.2 15.0 17.3 27.8 20.4 1.5 29.4 15.2 6.3 11.3 30.2 21.3 20.3 39.9 22.7 5.0 17.0 23.4 20.8 9.3 19.0 21.1 15.4 17.0 12.7 28.8 0.2 1.5 24.2 29.1 6.1 8.2 84.6 204.5 299.2 10.7 46.2 3.9 16.1 24.7 108.0 7.0 1.6 12.9 16.3 33.5 6.1 9.3 10.5 39.5 59.6 10.5 19.3 40.3 4.9 29.0 3.6 18.6 18.8 8.0 5.4 61.2 8.2 12.5 22.7 8.5 0.1 11.6 13.0 18.4 0.1 23.7 25.7 10.9 5.4 0.2 16.4 6.3 88.2 0.6 26.5 20.3 9.3 15.1 0.3 4.8 13.3 54.1 21.8 1.1 27.1 8.2 14.8 60.7 102.7 61.6 44.3 127.8 40.4 37.8 34.0 41.7 62.0 40.0 26.8 33.6 62.1 56.9 122.0 67.0 51.8 80.5 15.4 16.4 15.6 18.2 14.9 16.7 20.2 16.6 17.3 20.3 17.0 17.0 65.2 16.0 9.7 2.6 28.6 10.5 29.6 31.8 12.5 0.8 16.5 11.3 5.5 11.5 22.7 18.4 2.1 22.7 36.7 83.1 41.1 47.8 9.4 12.3 27.4 32.1 31.7 12.8 0.7 64.0 32.5 32.8 26.5 16.2 7.6 122.4 37.1 31.3 84.8 1.7 0.6 39.4 12.2 36.8 19.2 39.5 28.9 47.8 24.9 5.6 75.5 10.4 64.9 1.0 1.0 41.8 116.7 23.7 54.0 19.1 128.0 93.7 18.0 0.8 6.6 13.2 36.3 0.5 0.4 5.1 9.2 10.4 32.3 25.0 34.6 29.6 IFNA1 "IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA@, IFNA13" ENSG00000197919 "Interferon alpha 1" P01562 9 21440439-21441316 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.2;hTERT-RPE1: 2.2" HPA047557 Uncertain "Secreted to blood" NA NA 10000 "Cluster 20: HeLa - Mitochondria" "HPA047557: AB_2680087" "unprognostic (3.14e-1)" "unprognostic (1.55e-1)" "unprognostic (9.75e-2)" "unprognostic (5.88e-2)" 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.1 0.1 0.4 0.1 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA10 IFN-alphaC ENSG00000186803 "Interferon alpha 10" P01566 9 21206181-21207143 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA13 ENSG00000233816 "Interferon alpha 13" P01562 9 21367424-21368962 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.4" "Cell type enriched" "Detected in single" 17 "Granulosa cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Granulosa cells - Unknown function" "HPA047557: AB_2680087" 0.0 0.0 0.8 0.0 1.4 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.2 1.0 0.6 0.5 0.6 0.7 0.5 0.1 1.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA14 "IFN-alphaH, LEIF2H" ENSG00000228083 "Interferon alpha 14" P01570 9 21239002-21240005 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "Cluster 41: Macrophages - Immune response" "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA16 IFN-alphaO ENSG00000147885 "Interferon alpha 16" P05015 9 21216373-21217311 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA17 "IFN-alphaI, LEIF2C1" ENSG00000234829 "Interferon alpha 17" P01571 9 21227243-21228222 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA2 "IFN-alphaA, IFNA" ENSG00000188379 "Interferon alpha 2" P01563 9 21384255-21385398 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "brain: 1.6" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 2.5;Granulosa cells: 1.7;Oligodendrocytes: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA 253000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA047557: AB_2680087" 0.0 0.0 0.8 0.0 1.6 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.6 0.2 0.8 0.5 0.8 0.7 0.7 0.6 0.2 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA21 IFN-alphaI ENSG00000137080 "Interferon alpha 21" P01568 9 21165637-21166660 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA4 "IFN-alpha4a, MGC142200" ENSG00000236637 "Interferon alpha 4" P05014 9 21186694-21187671 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA5 IFN-alphaG ENSG00000147873 "Interferon alpha 5" P01569 9 21304326-21305312 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA6 IFN-alphaK ENSG00000120235 "Interferon alpha 6" P05013 9 21349835-21351378 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "Cluster 57: B-cells - Immune response" "HPA047557: AB_2680087" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA7 "IFN-alphaJ, IFNA-J" ENSG00000214042 "Interferon alpha 7" P01567 9 21201469-21202205 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA8 IFN-alphaB ENSG00000120242 "Interferon alpha 8" P32881 9 21409117-21410185 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "HPA047557: AB_2680087" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNAR2 IFNABR ENSG00000159110 "Interferon alpha and beta receptor subunit 2" P48551 21 33229901-33265675 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 211.2;U-266/70: 261.6;U-266/84: 145.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.00e-2)" "unprognostic (7.83e-3)" "unprognostic (4.98e-2)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-3)" "unprognostic (8.05e-2)" "unprognostic (4.17e-2)" "unprognostic (2.11e-2)" "unprognostic (7.65e-2)" "unprognostic (4.42e-1)" "prognostic unfavorable (7.54e-7)" "unprognostic (9.70e-3)" "unprognostic (2.39e-1)" "unprognostic (5.12e-3)" "unprognostic (1.85e-2)" 21.3 9.0 13.2 33.2 13.6 29.1 16.4 11.5 14.8 12.7 9.7 16.7 17.4 11.7 8.2 8.0 11.7 21.0 13.4 11.0 14.3 14.3 28.7 22.6 33.5 16.7 14.0 11.8 10.0 12.5 10.1 22.9 15.1 10.1 17.4 8.3 13.7 11.3 9.0 7.0 16.2 18.3 13.6 41.0 14.8 5.3 15.8 33.9 10.7 10.8 36.4 38.2 9.0 14.0 17.0 18.4 9.9 23.7 11.9 27.3 16.2 18.1 45.1 14.2 15.7 24.4 20.8 28.3 12.8 25.4 22.8 10.9 15.2 9.2 15.0 18.3 19.9 100.9 19.1 22.2 17.5 17.5 38.0 20.7 8.7 16.8 18.5 24.8 46.0 41.5 30.2 211.2 13.7 9.1 44.0 19.6 18.3 24.2 11.7 14.9 53.4 50.7 30.8 31.9 26.6 14.2 29.5 28.2 23.9 10.4 4.4 30.5 32.2 15.3 9.3 12.5 10.1 261.6 145.3 64.3 20.5 60.3 37.5 44.5 38.5 63.8 31.2 65.0 32.2 25.7 37.9 29.3 36.6 17.1 27.5 30.8 101.2 35.2 73.4 101.0 65.8 41.3 13.2 13.6 11.5 14.8 11.0 14.3 16.7 14.0 15.1 13.6 15.8 14.0 35.6 60.9 16.1 19.6 49.4 6.8 43.8 41.7 2.8 6.6 11.4 12.4 2.2 20.0 23.6 11.0 6.2 28.9 64.4 6.0 3.9 67.5 3.0 6.7 10.0 39.0 3.0 27.6 44.4 62.7 72.1 15.4 4.6 8.5 31.7 11.8 44.6 19.6 44.9 20.2 42.3 4.4 4.1 73.5 17.1 3.3 7.5 58.5 19.6 74.9 47.9 6.4 89.6 51.3 29.4 73.8 5.9 9.1 188.8 89.5 17.3 10.2 35.2 5.6 0.0 16.8 12.5 4.2 19.9 4.3 5.7 23.5 43.9 2.5 4.9 83.2 IFNB1 "IFB, IFF, IFNB" ENSG00000171855 "Interferon beta 1" P01574 9 21077104-21077942 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "Hofbauer cells: 2.2;Macrophages: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BJ hTERT+ SV40 Large T+ RasG12V: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA073843 Supported "Secreted to blood" NA NA 3750 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "HPA073843: " "unprognostic (2.38e-1)" "unprognostic (2.60e-4)" 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IFNE IFNE1 ENSG00000184995 "Interferon epsilon" Q86WN2 9 21480839-21482313 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 1.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 4.4;Basal respiratory cells: 3.7;Club cells: 1.2;Glandular and luminal cells: 1.5;Prostatic glandular cells: 2.9;Urothelial cells: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 3.2;HeLa: 9.6;hTERT-RPE1: 9.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.52e-3)" "unprognostic (8.36e-2)" "unprognostic (5.44e-2)" "unprognostic (1.56e-5)" "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-1)" "unprognostic (2.68e-2)" "unprognostic (1.14e-2)" "unprognostic (1.43e-2)" "unprognostic (9.63e-3)" "unprognostic (1.04e-1)" "unprognostic (3.27e-2)" "unprognostic (6.58e-3)" "unprognostic (3.34e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.8 0.6 0.0 0.0 0.3 0.1 0.9 1.5 0.4 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.3 0.6 0.0 0.7 0.1 0.2 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.0 0.5 0.0 0.3 0.0 0.2 1.1 0.9 0.3 1.1 1.9 0.0 0.0 0.9 0.9 0.1 3.2 0.2 0.1 0.2 0.0 2.1 0.0 0.6 0.6 0.3 1.1 0.0 2.0 0.3 0.0 0.0 0.0 9.6 0.0 0.5 0.0 0.0 0.8 0.4 1.2 1.8 9.9 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.8 0.0 0.1 0.3 0.2 0.3 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.4 3.7 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.9 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.7 IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159740 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.5;lymphoid tissue: 7.4" "Group enriched" "Detected in many" 12 "dendritic cells: 283.2;T-cells: 200.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "gdT-cell: 5.5;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.6;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010344 Approved "Secreted to blood" NA NA 1470 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 7: Non-specific - Mitochondria" "CAB010344: AB_2123447" "unprognostic (2.16e-4)" "unprognostic (1.93e-3)" "unprognostic (9.21e-2)" "unprognostic (1.04e-4)" "unprognostic (5.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.33e-1)" "unprognostic (3.17e-4)" "unprognostic (7.79e-2)" "unprognostic (7.97e-3)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (7.62e-9)" "unprognostic (3.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.32e-2)" "unprognostic (7.38e-3)" 0.7 0.7 0.1 3.5 0.2 11.5 0.3 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.0 0.0 0.3 1.5 1.8 7.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.9 0.2 0.0 0.0 0.3 0.2 0.0 1.3 0.4 0.1 0.1 0.5 0.3 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.4 6.6 0.0 0.4 0.5 3.7 0.1 0.9 0.0 0.0 0.1 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.0 0.0 0.0 3.1 3.2 1.3 0.0 0.0 0.0 4.8 5.5 0.2 1.5 0.0 0.0 0.0 0.0 283.2 0.1 0.0 0.0 0.2 1.0 1.1 1.3 0.0 0.4 0.0 0.0 0.0 1.5 6.1 1.1 0.0 0.0 1.4 1.2 0.1 0.0 0.0 0.5 0.0 4.4 5.5 0.0 0.0 10.4 7.2 0.0 0.0 0.0 19.6 0.0 0.1 0.0 1.1 0.0 10.9 0.2 0.0 0.3 0.0 0.0 0.0 1.0 2.9 0.0 0.0 0.8 4.0 0.0 200.1 0.0 0.2 0.2 IFNK ENSG00000147896 "Interferon kappa" Q9P0W0 9 27524290-27526498 "Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "brain: 4.1;choroid plexus: 2.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 0.5;head and neck cancer: 0.6;urothelial cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: Endometrium - Transcription" "unprognostic (5.58e-3)" "unprognostic (4.64e-3)" "unprognostic (1.06e-1)" 0.0 0.0 1.0 0.0 3.4 0.0 0.0 1.5 1.7 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.5 0.0 0.0 0.0 0.0 3.2 2.4 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.4 1.5 1.7 0.8 1.5 3.2 2.4 2.6 2.0 3.2 4.1 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNL1 "IL-29, IL29" ENSG00000182393 "Interferon lambda 1" Q8IU54 19 39296407-39298673 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "dendritic cells: 3.0;Langerhans cells: 6.4;NK-cells: 14.4;T-cells: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 2.7;MAIT T-cell: 2.8;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.7;myeloid DC: 2.3;naive CD8 T-cell: 1.4;NK-cell: 4.6" "Group enriched" "Detected in many" 33 "dendritic cells: 2.3;NK-cells: 4.6;T-cells: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 97000 "Cluster 48: NK-cells - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.08e-2)" "unprognostic (8.74e-2)" "unprognostic (2.46e-4)" "unprognostic (5.76e-2)" "unprognostic (6.91e-3)" "unprognostic (5.73e-3)" "unprognostic (3.94e-2)" "unprognostic (4.80e-2)" "unprognostic (2.96e-5)" "unprognostic (7.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 2.8 0.0 1.3 2.7 2.3 0.0 0.1 1.4 0.0 4.6 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.5 0.0 0.0 0.4 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.6 0.0 0.0 0.0 IFNL2 "IL-28A, IL28A" ENSG00000183709 "Interferon lambda 2" Q8IZJ0 19 39268396-39270188 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 15 "Breast myoepithelial cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "HDLM-2: 10.9" CAB025489 Uncertain "Secreted to blood" NA NA "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "CAB025489: " "unprognostic (1.37e-1)" "unprognostic (2.84e-1)" "unprognostic (1.05e-1)" "unprognostic (2.11e-2)" "unprognostic (1.08e-1)" "unprognostic (6.96e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNL3 "IL-28B, IL28B, IL28C" ENSG00000197110 "Interferon lambda 3" Q8IZI9 19 39243553-39245129 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 1700 "unprognostic (2.67e-1)" "unprognostic (9.19e-2)" "unprognostic (4.17e-1)" "unprognostic (6.86e-2)" "unprognostic (1.89e-2)" "unprognostic (1.66e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNW1 ENSG00000177047 "Interferon omega 1" P05000 9 21140214-21142145 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 86.7;cervix: 89.0" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 1279.3;Leydig cells: 1103.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Cell line enhanced" "Detected in some" "ASC diff: 37.9;HDLM-2: 49.6;K-562: 22.4;Karpas-707: 11.3;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048946 Approved "Secreted to blood" NA NA 103000000 330000000 "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" 86.7 5.1 1.2 27.1 1.8 0.9 38.7 0.3 2.3 89.0 1.3 6.9 5.4 46.9 10.6 6.6 13.0 21.5 15.1 2.2 1.0 3.1 83.5 11.6 6.5 2.5 1.1 9.0 3.9 1.4 1.2 24.2 2.0 38.5 6.7 5.4 7.6 33.4 8.5 4.9 5.7 74.3 1.2 9.8 7.7 7.6 2.0 3.1 25.4 5.9 3.7 21.3 22.7 0.9 0.3 0.0 0.0 0.0 37.9 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 22.4 11.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.2 0.2 1.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.4 1.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.8 0.3 2.3 2.2 1.0 2.5 1.1 2.0 1.2 2.0 0.9 11.8 3.2 2.2 1.0 8.5 2.5 0.7 0.0 1.8 168.1 4.0 6.2 0.4 2.8 0.7 0.0 0.0 1.1 0.6 0.2 0.0 0.0 17.5 35.8 1279.3 38.9 0.0 5.3 1.2 0.6 1.5 259.7 2.6 34.5 0.0 0.3 6.4 243.0 122.0 0.0 123.9 0.0 16.2 25.8 12.5 58.0 1103.2 42.0 14.2 27.2 3.6 4.4 0.0 0.5 0.9 0.1 0.0 193.4 66.9 1.2 0.0 1.4 0.1 9.0 0.0 139.3 19.6 1.9 1.2 1.6 2.7 1.2 9.1 69.4 0.2 0.4 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGFALS ALS ENSG00000099769 "Insulin like growth factor binding protein acid labile subunit" P35858 16 1790413-1794971 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 116.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 85.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.9;U-266/70: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040692, HPA040948" Supported "Secreted to blood" NA NA 14700000000 26000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA040692: AB_10794067, HPA040948: AB_10794999" "unprognostic (2.74e-3)" "unprognostic (1.95e-1)" "unprognostic (9.13e-2)" "prognostic unfavorable (6.06e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-2)" "prognostic favorable (5.97e-4)" "unprognostic (5.54e-4)" "unprognostic (3.00e-1)" "unprognostic (1.17e-1)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.39e-1)" "unprognostic (5.51e-2)" 0.3 0.2 0.5 0.3 0.9 0.4 0.4 1.4 0.8 0.5 0.9 0.6 0.3 0.2 0.1 0.1 0.7 1.6 0.2 0.3 0.1 1.0 116.7 0.8 0.0 0.7 0.4 0.7 2.5 0.0 0.7 0.0 0.8 0.5 0.1 0.2 0.8 0.1 0.5 0.9 0.6 0.0 0.4 0.3 11.0 1.9 0.4 0.9 0.9 0.0 0.0 0.4 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.5 0.0 0.0 1.7 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 1.4 0.8 0.3 0.1 0.7 0.4 0.8 0.4 0.4 1.8 0.1 0.0 0.0 1.6 0.1 0.1 0.2 0.2 0.0 0.5 0.9 0.6 1.6 14.3 0.2 0.0 6.2 0.0 0.0 0.6 0.0 2.7 1.1 0.4 0.0 0.2 0.0 0.0 0.5 0.6 0.0 0.4 8.2 0.1 0.0 0.2 2.9 85.2 0.0 0.0 0.6 14.6 0.0 1.3 0.3 1.7 0.0 0.0 1.8 0.0 0.0 0.3 1.0 0.0 0.7 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.2 0.1 0.4 0.4 0.0 0.3 0.0 0.2 0.1 0.7 0.1 IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1198.4" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 994.8" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Hep G2: 54.7;U-2197: 84.9;U-87 MG: 145.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 28100000 25000000 "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" 2.6 0.1 0.2 0.0 0.2 0.0 2.4 0.2 0.3 0.3 0.1 0.0 0.3 79.6 0.1 0.0 4.1 0.3 0.5 0.2 0.3 1.6 1198.4 0.1 0.1 0.8 0.3 46.3 0.5 0.0 0.5 204.5 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.3 1.1 0.3 0.0 0.0 0.0 0.2 0.2 0.2 6.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.6 0.3 1.4 0.1 1.6 0.3 0.0 0.0 0.7 0.0 0.0 0.3 0.5 54.7 0.3 1.1 0.1 0.1 0.7 11.3 0.1 0.6 0.3 0.0 0.2 0.1 1.3 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.3 0.0 2.2 0.0 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 84.9 0.0 0.0 0.0 0.2 145.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.3 0.8 0.3 0.9 0.2 0.3 0.2 0.4 0.0 0.5 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 5.7 1.0 35.8 0.7 0.0 0.0 0.9 0.0 0.0 0.0 11.0 0.1 4.7 94.3 0.9 3.5 10.7 0.1 0.0 1.6 1.8 0.0 15.9 0.0 2.1 6.8 994.8 1.7 0.0 0.1 0.0 0.0 14.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.1 0.5 0.0 0.0 3.4 0.8 0.0 0.0 0.0 IGFBP2 IBP2 ENSG00000115457 "Insulin like growth factor binding protein 2" P18065 2 216632828-216664436 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 956.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1379.1;Granulosa cells: 1649.7;Hepatocytes: 658.6;Theca cells: 2199.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2139.8;HMC-1: 5110.0;NB-4: 1106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077723 Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 303000000 810000000 "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA077723: AB_2686853" "unprognostic (2.58e-1)" "unprognostic (5.95e-2)" "unprognostic (1.94e-1)" "unprognostic (3.32e-3)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (9.11e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (5.04e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.22e-1)" 219.5 58.8 15.9 28.3 14.8 21.4 90.5 15.6 30.2 86.9 123.3 85.5 76.8 232.5 59.9 145.6 157.0 26.9 169.2 15.6 16.3 187.3 607.7 71.0 8.8 15.3 21.7 281.7 956.0 12.4 66.9 81.0 19.3 217.3 35.0 2.4 76.4 196.2 23.3 30.8 44.6 49.7 13.2 398.9 492.2 58.0 16.0 33.6 57.8 21.9 14.5 132.6 97.4 13.2 0.1 52.3 402.1 396.3 2139.8 652.9 8.5 125.2 61.9 6.1 0.6 1.2 1.5 0.1 171.7 0.8 15.2 11.5 145.4 156.9 0.6 0.8 84.9 91.3 0.2 26.3 53.3 38.6 5110.0 219.3 15.8 2.5 7.1 12.5 0.2 184.7 3.9 11.7 2.8 103.1 162.8 1106.5 437.4 98.2 4.8 139.2 9.1 2.0 2.0 117.1 84.1 443.4 0.3 3.4 2.6 362.2 332.4 67.3 0.5 1.6 2.4 1.6 6.2 6.2 0.9 9.7 6.0 177.4 478.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 15.9 14.8 15.6 30.2 15.6 16.3 15.3 21.7 19.3 13.2 16.0 13.2 354.3 3.2 0.6 2.0 3.3 13.8 534.0 238.2 19.4 0.2 79.0 498.0 12.5 11.5 40.1 264.8 2.1 1.8 5.4 86.4 29.4 3.0 1.0 153.2 1379.1 149.2 321.0 31.1 4.5 128.4 7.7 296.7 411.8 176.0 4.5 1649.7 92.1 658.6 5.3 0.0 0.8 191.6 54.9 24.1 5.0 4.9 5.6 21.8 3.6 13.1 1.3 3.6 3.1 1.0 1.0 60.7 51.3 79.4 0.4 255.7 4.2 1.2 195.9 1.7 105.2 17.9 435.7 6.0 35.8 103.3 5.5 2.2 16.0 2199.1 133.8 304.0 IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 1864.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 457.7;Basal respiratory cells: 777.7;Extravillous trophoblasts: 2064.1;Fibroblasts: 463.4;Urothelial cells: 809.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 54.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 54.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 8578.6;U-2197: 3469.4;U-87 MG: 1774.2" "Low region specificity" "Detected in all" CAB010360 Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3250000000 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" 350.6 16.2 15.6 28.5 20.2 1.2 278.2 12.2 24.1 291.8 18.9 96.7 67.8 547.3 43.1 28.2 130.9 44.6 284.6 16.5 22.5 65.9 721.3 37.5 68.3 20.7 13.7 233.1 14.4 28.0 98.1 1864.4 21.0 87.4 58.4 11.9 46.2 81.1 57.9 176.5 77.9 198.1 12.8 191.0 81.7 10.8 16.5 18.2 40.8 73.3 67.4 369.7 165.3 15.9 199.6 59.5 113.1 1.0 83.9 34.7 0.9 850.6 153.8 71.9 38.8 0.2 157.4 0.2 263.2 8578.6 35.6 466.5 1.5 3.4 29.2 0.6 0.1 0.3 20.8 0.2 21.9 0.4 1.6 285.7 12.8 15.1 53.8 112.3 0.7 0.0 0.1 3.2 26.8 1.2 1.3 1.4 7.8 1.8 10.9 0.8 0.4 81.4 53.2 423.6 13.6 32.7 293.9 11.4 15.3 250.6 1.5 0.7 0.5 815.4 1.7 3469.4 49.3 11.6 0.7 1.1 1774.2 0.3 282.1 0.0 0.0 0.0 10.1 0.0 8.0 0.0 10.9 10.7 0.0 0.0 4.9 8.1 0.1 0.0 0.0 54.5 0.8 4.5 15.6 20.2 12.2 24.1 16.5 22.5 20.7 13.7 21.0 12.8 16.5 15.9 260.4 3.2 3.9 0.7 1.9 457.7 148.9 777.7 8.0 2.8 12.6 30.4 12.6 8.6 409.7 228.1 0.0 94.1 10.0 0.7 11.7 145.6 1.3 32.3 220.1 168.0 273.7 5.3 2.5 2.0 2064.1 463.4 1.5 31.3 1.3 12.2 182.0 2.6 80.9 0.0 5.6 8.4 57.0 7.2 21.9 3.5 288.3 3.5 16.0 1.9 7.2 0.6 0.0 0.5 0.2 19.0 2.5 6.8 1.0 212.1 0.8 1.0 136.0 0.5 0.0 12.6 124.6 0.8 1.4 9.3 244.6 154.2 9.3 3.6 2.0 809.9 IGFBP4 "BP-4, HT29-IGFBP, IBP4, IGFBP-4" ENSG00000141753 "Insulin like growth factor binding protein 4" P22692 17 40443450-40457725 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 672.7;Endometrial stromal cells: 542.2;Endothelial cells: 502.3;Fibroblasts: 585.4;Hepatic stellate cells: 566.5;Hepatocytes: 501.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 19.5;NK-cell: 37.0" "Group enriched" "Detected in many" 5 "NK-cells: 37.0;T-cells: 19.5" "Cell line enhanced" "Detected in many" "A549: 1334.8;ASC diff: 961.5;ASC TERT1: 933.8;BJ: 1066.4;BJ hTERT+: 1088.2;HSkMC: 2001.2;U-2197: 882.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066240 Supported "Secreted to blood" NA NA 227000000 410000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA066240: AB_2685643" "unprognostic (1.03e-3)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.44e-3)" "unprognostic (1.00e-1)" "prognostic favorable (5.49e-4)" "unprognostic (4.55e-2)" "unprognostic (1.19e-2)" "unprognostic (2.28e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.36e-1)" "unprognostic (3.81e-2)" 884.7 248.1 26.0 307.7 26.9 2.4 754.6 25.3 46.5 1020.7 65.0 618.0 82.8 795.8 141.9 246.7 791.1 391.4 502.9 25.6 28.2 464.4 1475.9 390.1 60.0 29.5 34.1 1270.4 164.4 44.6 203.7 231.8 28.9 470.0 133.5 13.1 264.4 279.0 107.3 241.7 289.5 645.1 28.3 295.5 369.6 67.7 35.3 38.9 501.4 97.4 44.2 552.1 576.2 25.8 0.2 1334.8 66.8 0.5 961.5 933.8 2.2 1066.4 1088.2 199.7 154.4 59.7 17.3 0.3 563.7 511.0 27.2 11.9 22.6 6.8 90.2 4.8 1.3 4.3 91.3 89.9 601.2 2.9 0.5 2001.2 4.6 267.7 37.7 23.8 350.6 0.1 21.7 0.2 290.5 41.2 0.8 252.5 37.2 58.9 178.2 67.2 1.3 2.1 8.4 42.1 18.3 53.0 482.3 2.0 17.0 63.5 486.6 24.7 534.7 276.0 14.4 882.1 1.1 0.9 0.6 1.7 163.8 9.9 72.4 0.0 0.0 0.0 2.7 0.0 19.5 0.8 5.0 6.7 0.0 5.2 0.3 0.6 0.0 37.0 0.0 0.2 0.0 1.4 26.0 26.9 25.3 46.5 25.6 28.2 29.5 34.1 28.9 28.3 35.3 25.8 672.7 9.6 37.4 1.3 17.6 56.3 97.1 36.7 79.1 3.2 118.9 163.2 16.9 90.1 16.2 7.3 0.0 6.1 10.6 93.3 17.6 4.1 6.7 69.8 542.2 502.3 8.4 37.9 3.8 2.4 7.2 585.4 13.7 59.1 2.5 230.9 566.5 501.2 273.6 1.7 3.4 74.7 4.1 42.8 94.0 16.5 246.4 21.3 72.9 18.7 3.4 3.8 1.0 1.0 0.3 39.1 72.1 118.5 7.4 63.8 71.6 204.7 18.5 1.1 190.7 13.8 299.9 1.9 8.2 26.8 47.7 7.5 20.3 25.9 109.0 73.6 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1104.1;Ionocytes: 980.6;Leydig cells: 1828.2;Peritubular cells: 981.7;Sertoli cells: 1275.3;Skeletal myocytes: 2750.9;Smooth muscle cells: 1376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 831.3;BJ hTERT+: 2192.6;T-47d: 531.7;U-138 MG: 710.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: AB_2732640, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 375.1 221.8 35.6 178.2 35.1 0.7 354.6 21.9 30.9 1492.5 46.9 232.3 35.0 837.7 121.3 166.4 953.0 129.3 155.0 50.4 41.8 479.1 34.2 78.2 71.3 36.3 37.9 1323.4 30.7 30.7 272.8 290.7 31.5 241.4 66.2 105.4 111.0 121.8 470.9 129.0 139.3 621.2 28.1 38.7 323.5 28.8 43.8 95.0 326.2 292.9 45.9 259.2 382.9 62.4 0.0 0.0 210.6 0.9 237.1 7.5 0.8 831.3 2192.6 108.8 10.4 0.0 1.0 0.1 3.3 2.3 0.0 0.1 26.2 0.0 5.6 0.1 8.2 218.1 4.4 0.2 103.1 0.1 1.8 33.1 0.0 14.7 0.1 24.8 0.1 0.2 0.7 0.1 0.5 70.9 0.9 1.2 2.3 0.0 3.4 0.3 0.8 1.2 70.3 249.1 14.5 8.5 14.6 100.4 0.0 12.8 531.7 0.1 80.3 710.2 42.2 109.3 41.0 0.7 0.1 0.1 1.4 0.1 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 35.1 21.9 30.9 50.4 41.8 36.3 37.9 31.5 28.1 43.8 62.4 237.3 3.2 4.4 40.1 20.6 102.5 13.5 211.0 25.0 8.7 73.9 199.9 92.0 5.7 251.6 112.2 6.2 3.9 1.7 0.0 5.9 10.3 8.4 140.2 250.7 120.8 0.0 0.0 6.0 0.0 4.5 1104.1 30.5 128.5 2.5 11.4 49.6 1.4 8.7 3.3 13.7 0.0 980.6 0.6 189.7 39.9 1828.2 18.4 101.4 29.0 0.6 674.4 0.0 5.5 0.4 2.2 0.0 981.7 5.5 17.0 0.0 1.1 120.9 18.7 1275.3 2750.9 1376.0 2.2 3.0 17.7 67.9 5.6 18.4 124.7 0.1 16.8 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 580.8;Fibroblasts: 1360.5;Leydig cells: 1030.8;Peritubular cells: 1495.9;Sertoli cells: 1170.1;Smooth muscle cells: 420.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 1163.6;BJ: 476.9;BJ hTERT+: 683.3;fHDF/TERT166: 1045.9;hTERT-RPE1: 468.5;U-87 MG: 631.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 145.8 90.2 28.1 9.2 32.6 0.4 150.5 31.8 40.8 276.6 71.6 75.5 20.8 117.2 129.5 75.8 237.4 36.8 107.0 28.4 33.1 30.6 7.7 40.4 8.7 32.7 29.2 136.8 15.9 4.8 106.3 15.7 33.2 129.3 28.0 6.6 35.9 122.2 38.5 39.2 52.5 39.0 36.7 45.2 67.6 22.2 41.7 6.8 58.4 102.2 9.2 127.1 214.1 27.2 135.3 219.6 0.2 177.3 313.9 1163.6 0.8 476.9 683.3 126.9 69.0 23.2 294.7 0.0 68.5 1045.9 96.4 453.3 3.0 42.3 26.2 1.2 2.8 4.4 37.1 33.3 111.9 0.8 1.1 325.5 2.3 57.4 11.9 468.5 30.5 7.5 0.6 9.3 53.1 0.5 6.6 1.0 6.8 4.1 150.4 2.3 4.9 5.6 10.1 3.3 1.3 8.7 152.2 0.0 10.9 4.0 6.3 0.5 132.2 87.2 41.2 95.5 18.0 5.3 10.7 0.6 631.6 6.7 49.5 0.0 0.0 31.6 0.6 6.8 3.4 0.1 1.0 5.4 2.1 0.0 0.5 6.8 0.0 0.0 20.1 0.0 0.0 1.5 28.1 32.6 31.8 40.8 28.4 33.1 32.7 29.2 33.2 36.7 41.7 27.2 83.9 6.4 4.2 2.0 3.4 113.6 41.0 580.8 23.9 2.5 5.9 29.0 21.1 10.0 37.6 20.2 0.0 3.0 3.5 0.2 11.7 87.9 9.6 4.9 99.2 71.9 0.0 3.2 3.1 8.0 4.9 1360.5 30.5 2.5 0.0 2.3 116.4 0.8 7.6 0.0 3.6 0.3 50.8 6.8 122.8 32.6 1030.8 15.2 144.1 19.7 2.5 51.1 0.0 1.5 0.9 77.1 0.0 1495.9 9.6 94.9 0.0 15.2 13.9 2.8 1170.1 102.3 420.9 3.8 6.8 8.0 87.8 3.4 14.1 0.4 0.0 34.1 IGFBP7 "FSTL2, IGFBP-7, MAC25, PSF" ENSG00000163453 "Insulin like growth factor binding protein 7" Q16270 4 57030773-57110385 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 11440.4;Peritubular cells: 11731.6;Sertoli cells: 8184.6;Smooth muscle cells: 4434.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 693.6;BJ hTERT+: 643.1;hTERT-RPE1: 1471.3;RPTEC TERT1: 682.7;TIME: 1009.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002196, CAB020668" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 30300000 190000000 "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "CAB020668: , HPA002196: AB_1079107" "unprognostic (2.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.82e-2)" "unprognostic (5.97e-3)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "unprognostic (2.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-2)" "unprognostic (2.57e-1)" "unprognostic (6.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" 833.0 374.9 99.4 151.1 124.0 44.2 583.2 112.7 149.7 640.3 1299.1 473.1 105.6 653.2 260.4 115.3 618.1 405.7 1117.2 132.7 143.8 1298.6 283.2 532.4 133.1 185.2 138.7 359.1 270.1 77.2 246.0 66.6 146.4 506.0 83.2 4.7 193.7 659.0 185.6 193.6 259.6 334.9 136.8 436.9 267.4 259.2 187.9 48.9 995.3 91.8 81.9 546.4 494.0 132.6 1.3 4.8 1.1 0.0 134.8 50.4 4.7 693.6 643.1 59.2 19.0 2.8 0.1 0.3 433.7 33.5 35.3 70.2 0.7 111.1 15.7 1.3 5.4 2.5 78.7 0.5 207.7 17.1 17.9 234.7 55.8 96.8 26.2 1471.3 138.2 0.6 0.5 0.9 142.8 0.0 0.5 74.5 5.9 0.0 1.3 13.4 0.4 2.8 682.7 0.0 1.0 1.8 130.2 9.5 0.0 276.3 1.8 64.6 1009.4 60.5 46.4 7.8 114.8 41.1 0.4 1.4 159.2 58.3 1.8 2.0 3.9 21.7 0.1 4.1 0.1 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.3 10.8 4.5 0.4 0.1 1.7 99.4 124.0 112.7 149.7 132.7 143.8 185.2 138.7 146.4 136.8 187.9 132.6 2254.8 112.2 20.2 164.9 16.2 238.5 127.2 300.5 24.5 5.9 27.7 53.5 148.2 20.0 90.6 2087.4 22.9 6.6 76.9 1.4 516.5 2455.3 75.9 1235.5 702.2 2740.1 1.2 82.7 0.7 15.1 8.3 1435.9 29.0 381.3 15.8 1205.0 3079.4 16.4 26.5 0.0 3.7 1.0 61.1 101.9 375.7 335.4 11440.4 70.4 944.5 151.8 41.8 17.1 345.0 11.6 0.8 84.6 1.5 11731.6 11.0 113.3 0.0 692.2 731.0 12.5 8184.6 155.0 4434.0 36.6 38.6 9.9 179.1 5.7 51.3 759.1 2.5 64.0 IGFBPL1 bA113O24.1 ENSG00000137142 "Insulin like growth factor binding protein like 1" Q8WX77 9 38406528-38424454 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "thyroid gland: 16.5" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;Excitatory neurons: 2.5;Hofbauer cells: 1.9;Inhibitory neurons: 1.6;Oligodendrocyte precursor cells: 2.5;Spermatogonia: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 360.4;NTERA-2: 104.2;RH-30: 97.5;SCLC-21H: 334.3;SH-SY5Y: 332.6;SuSa: 241.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051354 Uncertain Uncertain Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA051354: " "unprognostic (5.63e-2)" "unprognostic (3.33e-1)" "unprognostic (5.22e-2)" "unprognostic (2.42e-1)" "unprognostic (2.56e-2)" "unprognostic (1.92e-1)" "unprognostic (1.30e-1)" "unprognostic (5.66e-2)" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.94e-1)" "unprognostic (3.92e-2)" "unprognostic (1.59e-2)" "unprognostic (6.67e-2)" 0.8 1.5 2.4 0.5 4.2 0.5 0.1 3.4 2.8 0.2 1.4 0.5 0.9 0.7 0.1 0.3 0.3 0.6 1.3 2.6 2.0 0.2 0.3 0.8 0.2 1.5 2.3 0.1 0.9 0.0 1.1 0.6 1.7 0.4 0.3 0.3 0.1 1.6 0.2 0.2 0.6 1.1 1.0 0.1 1.6 2.1 2.8 2.9 16.5 0.0 0.1 0.5 0.1 1.8 0.0 8.6 360.4 0.4 0.0 0.0 0.2 2.4 0.0 0.5 0.3 0.1 0.2 0.1 1.3 0.3 0.0 0.1 44.0 0.0 0.5 0.0 2.7 0.1 1.2 0.2 0.0 1.7 1.2 0.4 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.2 2.5 0.1 0.3 0.2 104.2 0.5 0.7 0.1 97.5 0.9 0.0 0.2 334.3 332.6 6.4 0.5 0.0 241.3 2.3 2.3 0.4 0.1 7.7 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.5 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.0 2.4 4.2 3.4 2.8 2.6 2.0 1.5 2.3 1.7 1.0 2.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.3 0.6 0.1 0.0 1.8 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 IGFL1 UNQ644 ENSG00000188293 "IGF like family member 1" Q6UW32 19 46229742-46231243 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 113.0;salivary gland: 34.5;vagina: 31.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Basal respiratory cells: 12.5;Prostatic glandular cells: 4.4;Squamous epithelial cells: 2.1;Suprabasal keratinocytes: 3.4" "Group enriched" "Detected in many" 7 "cervical cancer: 47.6;head and neck cancer: 60.7;melanoma: 23.3;urothelial cancer: 84.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 6.9;RT4: 25.6;SK-BR-3: 8.6" HPA014001 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA014001: AB_2668919" "unprognostic (1.35e-1)" "unprognostic (9.70e-2)" "unprognostic (2.89e-1)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.67e-2)" "unprognostic (3.06e-1)" "unprognostic (4.50e-3)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (3.23e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 113.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 34.5 0.0 0.0 3.5 0.0 0.0 0.0 0.3 0.1 1.0 0.0 0.8 0.0 0.0 4.8 0.4 31.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 6.9 0.0 1.9 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.2 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 12.5 0.0 0.0 0.5 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.4 0.3 2.1 3.4 0.0 0.0 0.0 0.0 0.2 IGFL2 UNQ645 ENSG00000204866 "IGF like family member 2" Q6UWQ7 19 46143106-46161299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 41.6" "Cell type enhanced" "Detected in some" "Astrocytes: 17.9;Excitatory neurons: 27.1;Inhibitory neurons: 29.3;Oligodendrocytes: 38.5;Spermatocytes: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 65 "CACO-2: 82.4;OE19: 166.9" HPA059137 Uncertain Approved "Nucleoplasm,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Plasma membrane" "HPA059137: AB_2683920" "unprognostic (1.53e-1)" "unprognostic (7.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.69e-2)" "unprognostic (7.30e-2)" "unprognostic (9.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (1.68e-1)" "unprognostic (4.26e-3)" "unprognostic (9.63e-3)" "unprognostic (4.14e-9)" "unprognostic (1.27e-1)" "unprognostic (2.76e-2)" "unprognostic (8.73e-2)" "unprognostic (9.91e-3)" 2.4 0.0 0.2 0.0 0.2 0.0 2.0 0.0 0.8 0.1 0.0 0.5 0.0 0.2 0.5 1.5 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 0.7 0.3 0.0 0.0 1.5 0.3 0.9 0.8 0.0 0.8 0.4 1.0 0.0 0.0 41.6 0.1 0.2 0.2 0.0 0.0 4.1 0.3 1.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 1.7 0.5 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.0 1.6 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 166.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.8 0.2 0.4 0.7 0.3 0.8 0.2 0.3 2.1 0.0 0.0 0.0 17.9 0.0 2.2 0.0 1.1 0.0 1.7 2.0 1.5 0.6 0.0 0.7 0.0 0.0 4.3 0.0 0.7 0.0 0.0 8.7 0.0 0.0 0.2 0.0 0.0 27.1 0.2 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 29.3 0.4 0.0 0.0 0.3 5.4 0.0 0.0 1.8 0.0 0.0 0.2 0.0 6.0 38.5 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 1.9 0.0 0.0 0.7 9.8 8.7 0.0 4.7 2.6 0.2 0.0 1.4 0.0 IGFL3 UNQ483 ENSG00000188624 "IGF like family member 3" Q6UXB1 19 46120067-46124688 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 27.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.1;Basal respiratory cells: 1.7;Exocrine glandular cells: 6.5;Melanocytes: 1.8;Suprabasal keratinocytes: 8.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.7;CACO-2: 1.0;hTEC/SVTERT24-B: 1.2;U-2 OS: 1.3;U-87 MG: 2.4" HPA062776 Uncertain "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 28: Keratinocytes - Keratinization" "HPA062776: AB_2684866" "unprognostic (8.61e-2)" "unprognostic (6.26e-2)" "unprognostic (2.69e-1)" "unprognostic (4.78e-2)" "unprognostic (7.45e-3)" "unprognostic (2.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.90e-1)" "unprognostic (1.86e-4)" "unprognostic (2.86e-2)" "unprognostic (1.90e-1)" "unprognostic (3.69e-2)" 0.0 0.0 0.6 0.0 1.2 0.1 1.5 0.0 1.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.1 0.0 1.1 0.2 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.1 0.5 0.1 0.0 0.3 27.7 0.0 0.1 0.2 0.0 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.2 0.2 1.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.2 1.2 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 1.2 0.5 0.3 1.1 0.2 1.1 0.2 0.4 2.6 0.0 0.0 0.0 0.0 0.0 3.1 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.4 1.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 IGFL4 ENSG00000204869 "IGF like family member 4" Q6B9Z1 19 46039748-46077118 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "retina: 19.5;skin 1: 6.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.2;Cone photoreceptor cells: 14.6;Excitatory neurons: 9.5;Inhibitory neurons: 10.1;Rod photoreceptor cells: 42.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.9;HaCaT: 3.5;OE19: 6.1" HPA047655 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA047655: AB_2680113" "unprognostic (1.22e-2)" "unprognostic (3.37e-2)" "unprognostic (2.57e-1)" "unprognostic (7.96e-2)" "unprognostic (5.48e-2)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" "unprognostic (8.25e-2)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (1.09e-2)" "unprognostic (3.59e-4)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" 0.0 0.3 1.3 0.1 1.1 0.1 0.1 1.0 2.2 0.0 0.0 0.1 0.4 0.3 1.3 1.0 0.2 0.5 1.0 1.2 0.4 0.1 0.1 0.3 0.4 0.0 0.1 0.9 0.0 0.5 1.6 0.1 0.4 0.4 0.2 19.5 0.5 0.0 0.2 6.9 0.3 0.0 0.0 0.2 0.2 0.3 0.3 0.0 0.8 0.0 0.0 0.3 0.0 1.8 0.0 3.9 0.1 0.2 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.9 0.1 0.5 0.0 0.1 0.5 3.5 0.0 0.0 0.0 0.4 0.6 0.0 0.6 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.4 0.0 0.4 0.0 0.3 0.2 6.1 0.2 0.0 1.7 0.9 0.0 0.2 0.2 0.3 0.0 0.1 0.9 0.4 0.2 0.7 0.4 0.3 0.7 0.2 0.2 0.4 0.3 0.1 0.1 0.6 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.3 1.1 1.0 2.2 1.2 0.4 0.0 0.1 0.4 0.0 0.3 1.8 0.0 0.0 0.0 2.6 0.0 1.0 0.0 0.8 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 10.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 3.7 0.0 3.5 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 0.0 0.0 0.1 0.8 2.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 IGHA1 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 7411.2;lymphoid tissue: 6397.6;salivary gland: 8904.9;stomach 1: 6664.9" "Group enriched" "Detected in many" 10 "B-cells: 17763.5;Plasma cells: 34095.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2571.8;naive B-cell: 1114.6" "Lineage enriched" "Detected in many" 284 "B-cells: 2571.8" "Cell line enhanced" "Detected in many" "HDLM-2: 17.4;RPMI-8226: 34.7;SH-SY5Y: 22.3;U-266/70: 78.2;U-266/84: 24.0" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 130000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" 200.6 41.7 1.4 1121.1 1.0 918.5 953.5 0.7 6.5 214.3 4.2 5973.6 7411.2 79.9 3.5 641.9 203.5 662.9 73.8 0.6 1.3 278.5 327.7 1305.3 1420.6 3.5 1.1 40.6 115.1 3.5 38.3 6.7 1.1 202.5 1338.5 0.0 8904.9 69.0 10.8 56.7 3788.8 69.5 1.4 6397.6 6664.9 23.2 1.0 131.0 447.3 0.4 1949.0 1616.2 302.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.8 0.0 0.0 3.6 0.0 0.0 0.0 17.4 0.0 3.7 0.0 0.0 0.0 5.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 4.1 14.4 5.5 0.0 0.0 3.8 4.3 34.7 0.0 0.0 9.7 22.3 2.6 0.0 0.0 0.0 0.0 1.6 5.1 0.0 3.9 4.2 3.2 78.2 24.0 2.2 0.0 2.4 0.0 3.8 3.0 0.6 1.3 0.3 1.0 2571.8 0.7 1.1 1.5 1114.6 0.4 1.0 9.0 0.9 0.9 1.7 1.0 508.3 1.4 1.0 0.7 6.5 0.6 1.3 3.5 1.1 1.1 1.4 1.0 1.9 11.8 131.4 783.5 0.0 17763.5 0.0 26.0 0.0 1.2 0.0 22.4 4.6 4.7 22.8 46.4 0.0 0.0 0.7 55.5 20.8 0.0 0.0 0.0 0.1 0.1 26.5 28.4 167.0 0.0 0.0 0.5 56.5 99.4 0.1 584.8 0.0 353.8 225.1 1.6 0.0 0.0 13.6 0.0 57.8 0.0 0.0 0.0 34.6 0.0 0.0 6.7 0.0 11.3 0.0 0.0 0.0 12.8 0.0 34095.8 33.2 0.0 1.4 16.0 0.0 0.0 2.0 13.6 0.0 0.0 0.8 0.0 6.0 2514.2 0.0 27.9 1.2 IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5017.7;salivary gland: 3728.4" "Group enriched" "Detected in many" 22 "B-cells: 3713.4;Plasma cells: 10918.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 876 "memory B-cell: 279.6;naive B-cell: 123.8" "Lineage enriched" "Detected in single" 1214 "B-cells: 279.6" "Group enriched" "Detected in some" 42 "U-266/70: 181.9;U-266/84: 63.9" "Not detected" "Not detected" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 67000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" 24.3 3.7 0.0 14.2 0.0 12.4 329.7 0.0 0.0 47.6 0.0 5017.7 15.3 8.9 0.0 219.7 35.0 0.9 4.8 0.0 0.0 49.7 35.1 134.2 6.8 0.0 0.0 5.3 30.3 0.0 4.9 0.3 0.0 37.7 8.8 0.0 3728.4 0.1 2.1 17.8 2261.3 1.0 0.0 700.9 670.1 1.1 0.0 22.4 59.8 0.0 13.0 93.4 67.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.9 181.9 63.9 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 279.6 0.0 0.1 0.1 123.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 12.4 0.0 3713.4 0.0 2.4 0.0 2.8 0.0 1.4 0.3 1.2 5.7 0.6 0.0 0.0 0.1 3.2 3.7 0.0 0.0 0.0 0.0 0.0 15.6 8.5 56.2 0.0 0.0 0.0 8.0 10.7 0.0 15.2 0.0 78.9 6.0 0.3 0.0 0.0 2.9 0.0 10.8 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 10918.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 12.3 0.0 0.4 325.4 0.0 4.8 0.2 IGHD "FLJ00382, FLJ46727, MGC29633" ENSG00000211898 "Immunoglobulin heavy constant delta" P01880 14 105836765-105845678 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 330.9" "Group enriched" "Detected in some" 47 "B-cells: 261.8;Plasma cells: 588.1;T-cells: 474.2" "Cancer enhanced" "Detected in many" "lung cancer: 58.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 63 "memory B-cell: 279.1;naive B-cell: 815.9" "Lineage enriched" "Detected in many" 93 "B-cells: 815.9" "Group enriched" "Detected in some" 7 "Daudi: 82.3;U-698: 95.8" CAB012703 Approved "Immunoglobulin genes" NA NA 14000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB012703: AB_10554307" "prognostic favorable (1.49e-6)" "unprognostic (1.84e-2)" "unprognostic (3.99e-2)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (2.08e-3)" "unprognostic (4.63e-2)" "unprognostic (3.28e-1)" "unprognostic (8.18e-2)" "unprognostic (6.16e-2)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-3)" "unprognostic (5.76e-2)" "unprognostic (2.64e-1)" "unprognostic (3.82e-3)" "unprognostic (4.30e-2)" 2.8 0.4 0.0 35.4 0.0 39.2 9.3 0.0 0.4 0.9 0.0 2.2 3.4 5.0 0.2 2.8 0.6 19.0 5.7 0.0 0.0 2.1 3.5 34.1 111.6 0.2 0.0 0.3 0.4 0.2 0.0 0.3 0.0 6.4 1.9 0.0 67.1 1.2 0.4 1.5 17.6 0.9 0.0 146.7 43.3 0.3 0.1 8.3 1.3 0.0 330.9 20.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 82.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 12.4 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 2.7 0.5 0.3 0.4 0.3 0.2 279.1 0.3 0.8 0.7 815.9 1.0 0.3 3.3 0.3 0.5 8.7 0.4 39.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 261.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.3 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.7 0.0 9.2 0.0 0.0 0.0 0.0 0.0 588.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 474.2 0.0 0.0 0.0 IGHD1-1 IGHD11 ENSG00000236170 "Immunoglobulin heavy diversity 1-1" P0DOY5 14 105919502-105919518 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHE ENSG00000211891 "Immunoglobulin heavy constant epsilon" P01854 14 105597691-105601728 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lymphoid tissue: 4.6;thyroid gland: 2.6" "Cell type enriched" "Detected in some" 50 "Plasma cells: 462.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "U-266/70: 3818.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 77000000 "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.18e-2)" "unprognostic (1.28e-2)" "unprognostic (1.54e-3)" "unprognostic (4.99e-1)" "unprognostic (4.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (2.40e-2)" "unprognostic (8.04e-2)" "unprognostic (3.88e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-2)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.63e-1)" 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 1.9 0.0 0.0 4.6 1.4 0.0 0.0 0.2 2.6 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.6 0.0 0.6 3818.2 371.6 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 462.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 16 "B-cells: 3900.5;Plasma cells: 9883.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Group enriched" "Detected in many" 9 "Karpas-707: 157.8;U-698: 392.7" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" 526.0 696.8 0.7 1661.1 0.6 681.1 203.2 0.5 4.5 518.2 2.8 302.1 103.7 210.6 18.4 334.4 661.5 312.9 143.2 0.4 2.2 491.7 356.1 962.4 3281.1 4.7 3.2 407.0 38.5 7.9 35.8 2.3 2.3 209.8 85.1 0.3 391.6 250.8 13.1 28.5 1008.8 27.6 12.7 11451.9 608.9 172.8 1.2 1773.7 1277.9 0.1 5826.8 3998.0 267.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.7 0.0 0.0 2.3 0.0 0.0 0.0 8.4 0.0 5.3 0.0 0.0 0.0 22.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 157.8 0.0 0.0 1.7 2.1 2.6 0.0 0.0 2.9 15.1 3.7 0.0 0.0 18.2 17.0 3.1 0.0 0.0 0.0 0.0 0.2 10.8 0.0 3.2 3.3 4.5 4.9 0.3 392.7 0.1 3.7 0.0 0.2 0.3 0.1 0.3 0.0 0.2 766.8 0.6 0.3 0.4 134.9 0.0 0.1 6.2 0.1 0.1 0.1 0.2 96.2 0.7 0.6 0.5 4.5 0.4 2.2 4.7 3.2 2.3 12.7 1.2 1.8 2.9 73.7 378.5 0.0 3900.5 0.0 8.1 0.0 0.0 0.0 0.5 0.0 2.8 22.8 9.3 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.5 0.0 0.1 8.5 13.9 83.4 0.0 0.0 0.0 13.6 8.2 0.0 209.4 0.0 46.1 52.9 0.1 0.0 0.0 5.0 0.0 62.8 0.0 0.9 0.0 9.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 5.4 0.0 9883.3 9.1 0.0 10.9 1.5 0.1 0.0 0.0 1.5 1.9 1.0 0.0 0.0 0.0 415.6 0.0 13.6 0.1 IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4319.4" "Group enriched" "Detected in some" 8 "B-cells: 2050.1;Plasma cells: 2918.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 447 "memory B-cell: 339.0;naive B-cell: 119.3" "Lineage enriched" "Detected in single" 661 "B-cells: 339.0" "Group enriched" "Detected in some" 4 "RH-30: 9.6;RPMI-8226: 25.1" HPA001245 Approved "Immunoglobulin genes" NA NA 250000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" 109.5 11.0 1.3 170.0 1.4 34.8 56.0 0.2 4.1 59.9 0.8 202.8 7.5 55.8 0.8 90.2 51.5 20.7 15.2 0.2 1.1 157.5 98.2 171.0 65.4 0.9 0.2 16.3 8.0 0.1 8.2 0.0 0.5 64.2 9.4 0.0 201.2 1.2 3.5 13.3 330.7 1.0 1.5 4319.4 87.2 2.3 0.3 16.7 134.4 0.0 226.0 100.4 104.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 25.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 339.0 0.5 0.0 0.3 119.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 34.5 1.3 1.4 0.2 4.1 0.2 1.1 0.9 0.2 0.5 1.5 0.3 1.8 0.2 54.5 305.3 0.0 2050.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 2.8 13.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 4.1 0.0 32.5 0.0 0.0 0.0 3.1 0.0 0.0 126.1 0.0 8.2 5.1 0.1 0.0 0.0 0.9 0.0 12.4 0.0 0.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2918.6 0.7 0.0 3.5 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.1 305.5 0.0 0.7 0.0 IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 7 "B-cells: 2548.4;Plasma cells: 4543.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 5 "HDLM-2: 23.8;Karpas-707: 18.7;U-698: 49.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" 63.6 17.6 0.1 90.8 0.3 65.4 23.8 0.1 1.5 37.9 1.0 30.0 11.6 22.8 0.3 32.2 104.4 8.4 6.7 0.1 0.6 72.8 42.4 194.9 346.3 2.8 0.1 13.4 6.3 0.1 6.8 0.1 0.4 41.4 8.8 0.0 69.9 12.7 1.9 2.3 100.9 1.6 1.2 1289.1 65.4 31.7 0.1 27.1 87.6 0.0 929.0 87.3 29.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 6.0 3.9 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 49.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 211.0 0.0 0.0 0.0 64.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.7 0.1 0.3 0.1 1.5 0.1 0.6 2.8 0.1 0.4 1.2 0.1 1.0 1.9 57.7 363.7 0.0 2548.4 0.0 9.7 0.0 0.0 0.0 0.5 0.1 1.9 18.6 11.2 0.0 0.0 0.0 2.0 7.0 0.0 0.0 6.5 0.1 0.2 5.3 13.2 24.5 0.0 0.0 0.0 9.1 2.6 0.0 195.5 0.0 22.9 64.2 0.1 0.0 0.0 7.4 0.0 62.8 0.0 16.4 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 4543.8 13.3 0.0 0.5 2.2 0.0 0.0 0.0 0.7 4.7 0.7 0.0 0.0 0.0 467.3 0.0 13.5 0.1 IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Group enriched" "Detected in some" 10 "B-cells: 964.5;Plasma cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 339.7" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" 80.0 2.1 0.4 2478.2 0.6 42.2 5.8 0.5 1.0 33.9 0.3 40.6 85.5 10.8 0.2 401.2 28.5 101.3 19.2 0.3 0.4 44.0 43.7 49.4 136.5 0.6 0.4 3.9 4.2 0.5 1.9 0.2 1.3 31.2 44.3 0.1 16.4 4.1 0.8 4.7 186.2 1.8 1.1 831.6 57.4 2.2 0.4 49.9 108.3 0.0 872.5 588.7 29.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 43.2 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.3 0.6 339.7 0.0 0.0 3.5 3.7 0.3 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.9 0.3 1.5 0.6 0.1 57.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 122.7 0.0 0.0 0.1 73.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.6 0.4 0.6 0.5 1.0 0.3 0.4 0.6 0.4 1.3 1.1 0.4 0.3 1.3 6.4 118.8 0.0 964.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.0 8.6 3.7 0.0 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.0 0.4 2.5 27.8 26.7 0.0 0.0 0.0 4.3 0.0 0.0 50.4 0.0 16.4 36.7 0.0 0.0 0.0 10.5 0.0 51.9 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.3 0.0 2099.3 0.2 0.0 10.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 152.3 0.0 12.8 0.1 IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 18 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.7;U-698: 1.8" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" 8.6 5.3 0.1 196.9 0.1 35.6 72.8 0.0 1.9 18.6 0.2 260.2 354.8 3.3 0.0 15.7 5.2 12.6 1.4 0.1 0.1 2.3 6.1 28.5 46.8 1.3 0.0 8.2 3.1 0.4 0.0 0.7 0.5 4.3 182.6 0.0 120.1 0.5 0.0 0.0 171.1 12.0 0.3 100.2 305.5 1.0 0.2 14.6 2.9 0.0 414.0 61.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.2 276.3 0.6 2.5 0.2 180.8 0.3 0.3 0.0 0.1 0.1 99.0 0.2 29.1 0.1 0.1 0.0 1.9 0.1 0.1 1.3 0.0 0.5 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1315.0;lymphoid tissue: 4112.3" "Group enriched" "Detected in many" 14 "B-cells: 3757.1;Plasma cells: 9906.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 16 "memory B-cell: 4278.4;naive B-cell: 6731.2" "Lineage enriched" "Detected in all" 19 "B-cells: 6731.2" "Group enriched" "Detected in many" 9 "Daudi: 4983.6;U-698: 4905.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB008643 Uncertain "Immunoglobulin genes" NA NA 110000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" 52.0 9.0 0.4 373.7 0.4 395.3 56.6 0.2 1.7 67.9 1.8 446.8 1204.9 11.1 10.2 66.8 38.5 141.7 50.5 0.2 0.4 48.4 84.7 180.6 3192.1 1.9 0.3 9.7 44.5 0.6 8.7 3.6 0.7 15.1 201.4 0.0 325.1 6.1 2.7 1.7 1315.0 7.9 1.0 4112.3 528.9 70.9 0.7 117.3 37.0 0.7 497.1 128.0 10.5 0.5 4.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 4983.6 2.9 0.0 0.0 0.8 0.0 0.0 0.0 21.6 0.0 3.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 1.7 28.7 1.2 0.0 0.0 580.2 2.2 6.9 0.0 0.0 4.0 5.8 3.0 0.5 1.2 0.0 0.2 3.8 6.5 0.0 13.8 1.2 2.5 1.5 1.5 4905.9 0.0 2.4 0.0 10.8 5.4 5.6 3.1 1.2 2.3 4278.4 5.5 6.8 5.4 6731.2 4.5 3.8 25.4 11.4 4.5 346.1 11.4 815.2 0.4 0.4 0.2 1.7 0.2 0.4 1.9 0.3 0.7 1.0 0.7 0.5 1.0 38.5 254.5 0.0 3757.1 0.0 0.2 0.0 1.2 0.0 2.2 0.8 0.3 31.5 14.2 0.0 0.0 0.0 63.8 1.8 0.0 0.0 0.0 0.0 0.1 4.2 6.7 474.1 0.0 0.0 0.0 10.8 27.5 0.0 152.6 0.0 56.7 147.9 0.1 0.0 0.0 2.2 0.0 158.1 0.0 0.0 0.0 12.4 0.0 0.0 5.2 0.0 11.3 0.0 0.0 0.0 1.2 0.0 9906.5 0.3 0.0 2.2 1.5 0.0 0.0 0.4 16.8 0.0 0.0 0.2 0.0 0.0 415.0 0.3 4.1 0.1 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 76.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 231.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HL-60: 1.8;JURKAT: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 3100000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" 6.8 1.4 0.1 33.7 0.0 0.0 8.5 0.0 0.3 56.3 0.1 30.5 0.0 5.7 0.0 46.2 6.5 4.6 1.8 0.0 0.1 7.0 6.4 17.7 0.0 1.2 0.1 19.6 1.4 0.1 0.4 0.3 0.0 3.1 14.0 0.0 76.3 0.0 0.1 0.8 24.0 2.1 0.0 186.8 37.0 14.2 0.0 0.4 14.5 0.0 18.4 63.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.8 0.1 0.0 0.0 2.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 3.6 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 19.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 231.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 5.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.9;lymphoid tissue: 30.3;stomach 1: 17.5" "Cell type enriched" "Detected in single" 20 "Plasma cells: 2.0" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "U-266/70: 1.2;U-266/84: 1.3" "Immunoglobulin genes" NA NA 380000000 "Cluster 32: T-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" 0.2 0.1 0.0 3.7 0.0 1.8 18.9 0.0 0.0 0.3 0.0 4.5 1.1 0.5 0.0 6.4 0.2 0.6 0.1 0.0 0.0 0.2 0.2 3.5 7.6 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 6.1 0.0 11.5 0.0 0.0 0.1 2.3 0.7 0.0 6.9 17.5 0.1 0.0 2.9 0.3 0.0 30.3 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 1.1 0.6 0.3 0.0 1.1 0.7 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "urinary bladder: 204.7" "Group enriched" "Detected in some" 17 "B-cells: 2.4;Plasma cells: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.7" "Lineage enriched" "Detected in single" 58 "B-cells: 12.7" "Cell line enhanced" "Detected in single" "MOLT-4: 1.5" "Immunoglobulin genes" NA NA 120000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (9.63e-3)" "unprognostic (6.78e-2)" "unprognostic (5.64e-2)" "unprognostic (4.04e-2)" "prognostic favorable (7.25e-4)" "unprognostic (4.56e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-1)" "unprognostic (1.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "unprognostic (6.79e-2)" "unprognostic (1.36e-1)" 8.1 3.4 0.0 13.8 0.0 5.9 3.8 0.0 0.0 0.8 0.0 19.5 15.7 0.4 0.0 8.3 1.1 4.7 1.0 0.0 0.0 1.5 1.4 5.4 41.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 27.8 0.0 23.5 1.9 0.0 0.2 9.8 0.1 0.0 26.2 13.1 0.5 0.0 10.3 1.1 0.0 51.1 204.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 85 "Plasma cells: 231.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0;MOLT-4: 6.2;SCLC-21H: 1.1;U-698: 1.9" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" 7.7 1.4 0.0 0.0 0.1 0.1 6.5 0.0 0.0 21.4 0.1 56.9 0.0 6.9 0.0 7.0 5.7 77.4 0.7 0.0 0.1 7.0 4.8 18.0 0.0 2.5 0.0 2.0 0.8 1.8 0.5 0.0 3.0 4.6 139.1 0.0 55.9 13.0 0.1 0.5 31.7 6.8 0.0 170.2 31.0 0.1 0.0 0.0 25.2 0.0 0.0 162.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 1.3 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.1;lymphoid tissue: 47.1" "Cell type enriched" "Detected in some" 226 "Plasma cells: 10423.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cell line enriched" "Detected in some" 6 "MOLT-4: 11.2" "Immunoglobulin genes" NA NA 1100000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 6.3 0.3 0.0 5.8 0.0 2.5 3.6 0.0 0.0 1.5 0.0 12.0 22.1 1.1 0.2 2.1 1.2 14.5 1.6 0.0 0.0 2.7 0.9 4.5 13.5 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 14.4 0.0 16.4 0.9 0.0 0.0 18.0 0.2 0.0 47.1 9.9 0.2 0.0 3.7 1.1 0.0 36.5 4.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 6.7 0.5 0.9 0.0 5.5 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 1.4 23.0 0.0 0.0 0.0 1.1 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10423.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 128.8;lymphoid tissue: 98.5;urinary bladder: 227.1" "Group enriched" "Detected in some" 39 "B-cells: 8.3;Plasma cells: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 13.9" "Lineage enriched" "Detected in single" 140 "B-cells: 13.9" "Cell line enhanced" "Detected in some" "HL-60: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 190000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 57: B-cells - Immune response" "unprognostic (9.39e-3)" "unprognostic (4.50e-2)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (4.99e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "unprognostic (2.24e-1)" "unprognostic (8.09e-2)" 6.2 7.7 0.0 59.0 0.0 21.6 14.0 0.0 0.3 15.5 0.2 35.0 61.5 4.2 0.0 31.5 3.8 128.8 5.6 0.0 0.4 2.3 6.0 20.7 3.5 0.2 0.6 0.5 1.6 0.0 0.3 0.0 0.1 6.3 86.5 0.0 44.2 0.9 0.1 0.5 55.1 4.4 0.2 98.5 65.1 0.0 1.1 0.0 6.8 0.0 21.8 227.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.2 1.1 0.2 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 727.6;stomach 1: 502.1" "Cell type enriched" "Detected in single" 5 "Plasma cells: 2.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Group enriched" "Detected in some" 241 "memory B-cell: 24.6;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 247 "B-cells: 24.6" "Cell line enriched" "Detected in some" 8 "U-698: 12.4" "Immunoglobulin genes" NA NA 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.01e-3)" "unprognostic (2.93e-2)" "unprognostic (3.56e-3)" "unprognostic (2.38e-2)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (9.10e-2)" "unprognostic (2.50e-1)" "unprognostic (8.93e-2)" "unprognostic (2.91e-1)" 7.3 25.7 0.0 96.2 0.0 69.2 86.1 0.0 5.2 62.3 0.0 86.7 53.2 4.1 0.0 44.3 8.1 37.5 2.5 0.0 1.4 4.8 13.2 69.9 82.7 0.1 1.1 5.0 1.0 0.9 0.3 0.2 0.1 6.8 82.8 0.0 94.5 14.1 0.1 0.9 42.1 2.5 2.2 156.4 502.1 1.2 0.0 59.5 8.5 0.0 727.6 50.4 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.4 0.8 0.0 0.0 0.8 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.7 0.0 0.1 0.0 12.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 5.2 0.0 1.4 0.1 1.1 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.8;lymphoid tissue: 90.8;stomach 1: 47.0" "Cell type enriched" "Detected in single" 10 "B-cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.7" "Lineage enriched" "Detected in single" 97 "B-cells: 9.7" "Cell line enriched" "Detected in single" 7 "MOLT-4: 1.7" "Immunoglobulin genes" NA NA 110000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.57e-2)" "unprognostic (9.48e-3)" "prognostic favorable (3.34e-4)" "unprognostic (4.34e-2)" "unprognostic (8.37e-3)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.70e-2)" "unprognostic (3.83e-1)" "unprognostic (3.66e-2)" "unprognostic (8.11e-2)" 1.7 0.7 0.0 16.6 0.0 4.1 7.1 0.0 0.0 5.6 0.1 36.8 14.2 1.9 0.0 5.2 4.5 20.9 1.7 0.0 0.0 2.5 2.3 6.2 4.6 0.0 0.0 0.8 0.3 0.1 0.1 0.0 0.0 0.7 33.1 0.0 30.3 0.1 0.0 0.1 21.7 0.6 0.0 41.4 47.0 0.0 0.0 4.5 2.5 0.0 90.8 3.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.5;lymphoid tissue: 137.3;urinary bladder: 90.5" "Group enriched" "Detected in some" 6 "B-cells: 6.7;Plasma cells: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 193 "memory B-cell: 18.8;naive B-cell: 19.6" "Lineage enriched" "Detected in single" 197 "B-cells: 19.6" "Cell line enhanced" "Detected in some" "MOLT-4: 1.8;U-266/70: 1.0" "Immunoglobulin genes" NA NA 33000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (3.24e-4)" "unprognostic (7.42e-2)" "unprognostic (1.96e-2)" "unprognostic (5.03e-2)" "prognostic favorable (6.67e-6)" "unprognostic (5.44e-2)" "unprognostic (1.23e-2)" "unprognostic (1.53e-1)" "unprognostic (5.31e-2)" "unprognostic (8.27e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.21e-5)" "unprognostic (6.79e-2)" "unprognostic (3.21e-1)" "unprognostic (4.45e-1)" "unprognostic (7.87e-2)" 1.3 36.6 0.0 24.1 0.0 6.9 17.2 0.0 0.1 1.9 0.0 67.5 49.5 1.5 0.0 15.4 4.3 9.7 1.8 0.0 0.0 1.1 1.5 7.2 39.5 0.0 0.1 1.5 0.7 0.0 0.1 0.0 0.0 1.1 36.1 0.0 30.9 1.4 0.0 0.1 22.8 5.6 0.1 56.5 42.9 0.9 0.0 9.3 2.8 0.0 137.3 90.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-16 ENSG00000211944 "Immunoglobulin heavy variable 3-16 (non-functional)" A0A0C4DH30 14 106165205-106165730 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 3200000000 "Cluster 43: B-cells - Humoral immune response" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 14.1;lymphoid tissue: 12.8;salivary gland: 7.6;stomach 1: 16.7;urinary bladder: 20.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Cell line enriched" "Detected in single" 6 "MOLT-4: 1.3" "Immunoglobulin genes" NA NA 19000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" 0.1 0.1 0.0 12.8 0.0 3.3 1.1 0.0 0.0 2.8 0.0 10.3 14.1 0.4 0.0 0.5 1.1 1.1 0.5 0.0 0.0 0.1 0.7 2.4 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 11.1 0.0 7.6 0.5 0.0 0.2 6.0 0.6 0.0 5.3 16.7 0.0 0.0 0.0 0.0 0.0 2.2 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-38 ENSG00000211958 "Immunoglobulin heavy variable 3-38 (non-functional)" A0A0C4DH36 14 106410493-106411021 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.9;lymphoid tissue: 10.4;stomach 1: 5.9;urinary bladder: 7.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.4;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 34 "B-cells: 3.4" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "unprognostic (1.03e-5)" "unprognostic (5.11e-2)" "unprognostic (3.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.31e-3)" "unprognostic (8.40e-2)" "unprognostic (3.54e-2)" "unprognostic (2.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.75e-8)" "unprognostic (6.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.99e-1)" "unprognostic (2.52e-1)" 0.3 0.1 0.0 5.9 0.0 1.6 3.3 0.0 0.0 1.4 0.0 7.7 9.9 0.1 0.0 0.9 0.1 0.9 0.2 0.0 0.0 0.1 0.4 1.8 2.2 0.0 0.0 0.6 0.4 0.0 0.0 0.2 0.0 0.2 7.0 0.0 4.1 0.0 0.0 0.2 5.8 0.0 0.0 4.4 5.9 0.7 0.0 0.0 0.0 0.0 10.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-64 ENSG00000223648 "Immunoglobulin heavy variable 3-64" A0A075B6Q5 14 106657725-106658258 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;lymphoid tissue: 32.1;salivary gland: 21.0" "Cell type enriched" "Detected in some" 38 "Plasma cells: 88.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "memory B-cell: 11.1" "Lineage enriched" "Detected in single" 111 "B-cells: 11.1" "Cell line enhanced" "Detected in single" "HL-60: 1.1" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.09e-6)" "unprognostic (6.52e-2)" "unprognostic (2.11e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-3)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (8.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.33e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (3.93e-5)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.07e-2)" 1.7 0.1 0.0 2.0 0.0 8.6 7.2 0.0 0.4 0.7 0.0 17.9 6.9 0.9 0.0 1.2 1.9 4.1 1.2 0.0 0.0 0.8 2.2 4.3 0.0 0.1 0.0 3.3 3.6 0.0 0.1 0.0 0.0 0.5 1.2 0.0 21.0 0.4 0.0 0.1 11.3 1.3 0.0 32.1 6.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: Non-specific - Mitochondria" 8.3 0.5 0.2 140.3 0.1 10.9 84.2 0.0 0.8 12.9 0.3 130.9 20.4 3.3 1.4 35.4 7.8 46.3 4.8 0.5 0.0 1.5 4.2 36.7 48.8 0.1 0.0 5.1 8.1 0.1 0.1 0.1 0.0 4.1 145.2 0.0 28.9 11.5 0.0 3.8 68.8 3.6 0.1 67.4 74.8 0.5 0.0 16.5 2.9 0.0 272.7 40.5 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790691-106791233 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.7;lymphoid tissue: 121.6;urinary bladder: 101.3" "Cell type enriched" "Detected in some" 271 "Plasma cells: 3507.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "memory B-cell: 52.4" "Lineage enriched" "Detected in many" 50 "B-cells: 52.4" "Cell line enhanced" "Detected in some" "NB-4: 1.3;RH-30: 1.3;RPMI-8226: 1.2;TIME: 2.2;U-698: 5.8" "Immunoglobulin genes" NA NA 9600000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" 4.8 2.6 0.1 18.4 0.1 15.5 7.0 0.0 0.6 5.2 0.1 75.7 28.4 3.0 2.9 17.4 3.4 0.3 0.3 0.0 0.0 1.9 5.3 8.6 2.7 0.5 0.0 2.3 3.4 0.1 0.2 0.1 0.1 1.9 47.6 0.0 46.6 0.9 0.1 0.3 58.2 5.4 0.1 121.6 29.4 0.0 0.0 2.6 2.2 0.5 12.1 101.3 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.3 0.2 0.0 0.0 0.1 1.3 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.1 0.0 0.3 0.0 5.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 52.4 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.1 0.0 0.6 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.1 7.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3507.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Cholangiocytes: 1.5;Erythroid cells: 5.3;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cell line enhanced" "Detected in some" "Daudi: 1.4;HEL: 1.1;HL-60: 1.1;K-562: 1.7" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" 4.4 13.3 0.0 9.4 0.0 15.8 10.5 0.0 0.5 4.7 0.3 76.9 141.8 5.1 0.0 4.0 3.9 19.1 10.4 0.0 0.0 3.0 9.8 12.3 0.0 0.1 0.0 1.5 5.9 0.0 0.5 0.1 0.2 4.3 58.0 0.0 30.6 3.9 0.4 0.2 23.6 0.4 0.1 83.0 47.5 0.4 0.0 0.0 4.1 0.0 0.2 81.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 69.9 0.1 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.9;lymphoid tissue: 327.0;salivary gland: 102.6" "Cell type enriched" "Detected in some" 454 "Plasma cells: 19404.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 861 "Daudi: 2948.0" "Immunoglobulin genes" NA NA 27000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.47e-4)" "unprognostic (9.70e-2)" "prognostic favorable (8.33e-4)" "unprognostic (6.96e-3)" "unprognostic (1.42e-1)" "prognostic favorable (7.79e-4)" "unprognostic (1.06e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-1)" "unprognostic (3.07e-2)" "unprognostic (2.42e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (4.70e-6)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" 11.3 1.2 0.1 0.0 0.2 0.0 12.6 0.0 1.5 9.3 0.0 103.9 0.0 2.1 1.9 87.3 2.6 1.3 0.7 0.0 0.3 4.7 6.6 22.2 0.0 0.6 0.0 2.5 1.9 0.6 0.8 0.1 0.2 6.5 0.0 0.0 102.6 0.0 0.5 3.2 74.1 0.0 0.3 327.0 27.5 0.2 0.1 0.0 7.7 0.0 0.0 46.4 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 2948.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.1 1.1 0.2 0.0 0.0 0.1 1.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.7 0.3 0.4 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.5 0.0 0.3 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 42.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 1.4 27.5 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 19404.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 2.3 0.0 0.1 0.3 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in single" 36 "B-cells: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 6 "Daudi: 9.4;U-698: 4.8" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA006014: " 4.5 28.4 0.0 229.8 0.0 38.7 102.0 0.0 0.9 68.9 0.1 274.0 0.9 10.8 0.0 111.5 20.0 92.5 6.2 0.0 0.0 5.5 7.3 128.3 121.2 0.1 0.0 54.0 5.7 0.4 0.3 0.2 0.2 6.9 316.6 0.0 75.5 19.0 0.1 1.6 51.6 10.9 0.0 203.8 148.3 0.1 0.0 39.3 7.3 0.0 568.1 196.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 4.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 66.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGHV7-4-1 ENSG00000282122 "Immunoglobulin heavy variable 7-4-1" A0A0J9YVY3 14 106025145-106025630 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.4;lymphoid tissue: 133.9" "Cell type enriched" "Detected in some" 4 "Plasma cells: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 109 "memory B-cell: 8.3;naive B-cell: 13.5" "Lineage enriched" "Detected in single" 136 "B-cells: 13.5" "Cell line enriched" "Detected in some" 5 "Karpas-707: 5.4" "Immunoglobulin genes" NA NA 560000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" 3.9 2.9 0.3 58.3 0.0 39.0 21.1 0.0 0.6 7.7 0.2 60.8 8.3 0.5 0.0 4.7 0.8 3.1 0.8 0.0 0.0 2.1 2.8 49.1 7.5 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.0 2.6 97.4 0.0 42.2 8.7 0.3 0.2 42.9 0.2 0.1 68.5 24.2 0.2 0.0 45.6 5.9 0.0 133.9 10.4 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV7-81 ENSG00000211979 "Immunoglobulin heavy variable 7-81 (non-functional)" A0A0B4J1V7 14 106874583-106875071 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;lymphoid tissue: 18.3;stomach 1: 12.3" "Group enriched" "Detected in some" 12 "B-cells: 1.5;Plasma cells: 1.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 5.5;naive B-cell: 3.9" "Lineage enriched" "Detected in single" 14 "B-cells: 5.5" "Cell line enhanced" "Detected in some" "A549: 1.1;Daudi: 6.1;OE19: 1.2;U-698: 2.0" "Immunoglobulin genes" NA NA 270000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (5.71e-4)" "unprognostic (3.87e-1)" "unprognostic (1.06e-1)" "unprognostic (6.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.24e-1)" "unprognostic (2.07e-1)" "unprognostic (1.14e-2)" "unprognostic (6.16e-5)" "unprognostic (1.69e-3)" "unprognostic (1.78e-2)" "unprognostic (1.08e-1)" "unprognostic (5.63e-2)" "unprognostic (3.44e-1)" "unprognostic (3.63e-2)" 0.1 0.1 0.0 8.4 0.0 4.6 3.6 0.0 0.0 0.3 0.0 7.6 6.4 0.4 0.0 0.6 0.3 7.9 0.2 0.0 0.0 0.3 0.2 1.8 4.2 0.0 0.0 0.8 0.9 0.0 0.0 0.0 0.0 2.3 12.7 0.0 5.0 0.1 0.0 0.2 6.2 0.4 0.0 2.3 12.3 0.1 0.0 1.4 0.0 0.0 18.3 1.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.5 0.3 0.1 0.0 3.9 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV8-51-1 "IGHV(III)-51-1, IGHVIII-51-1" ENSG00000254167 "Immunoglobulin heavy variable IGHV8-51-1 (non-functional)" 14 106583501-106583807 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "MOLT-4: 10.8" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGIP "C5orf53, LOC492311" ENSG00000182700 "IgA inducing protein" A6NJ69 5 140125937-140129392 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 55.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.7;ASC TERT1: 13.1" "Low region specificity" "Detected in all" "HPA041877, HPA048615" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA041877: AB_2677721, HPA048615: AB_2680462" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" "unprognostic (2.00e-2)" "unprognostic (2.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (2.38e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.94e-1)" "prognostic favorable (6.25e-6)" "unprognostic (2.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.98e-2)" "unprognostic (7.77e-2)" 8.3 8.9 43.6 2.9 41.0 0.1 7.7 38.9 55.4 12.7 29.7 14.1 3.7 9.2 9.0 6.3 8.9 3.7 11.8 38.3 40.9 9.3 10.0 9.4 4.5 41.5 43.8 9.9 8.4 13.7 18.6 4.2 43.9 12.0 3.8 19.5 8.0 8.1 10.4 9.0 8.3 4.6 45.7 7.8 9.2 4.0 45.1 4.2 11.9 9.2 3.9 10.7 11.6 40.8 2.0 0.6 0.9 2.8 13.7 13.1 1.3 5.1 5.0 1.1 1.5 2.0 1.6 3.8 5.3 6.9 0.6 2.1 1.1 3.1 2.3 3.4 1.9 0.8 3.0 1.5 3.2 1.0 1.3 4.5 7.7 2.2 4.2 8.6 1.4 2.8 0.6 1.5 4.4 1.8 1.2 2.6 0.2 1.6 1.5 1.2 2.4 1.7 6.6 1.8 1.0 1.5 2.8 1.8 3.1 1.0 1.4 3.0 8.8 3.5 0.3 1.2 2.8 3.6 2.5 1.3 3.7 2.6 2.6 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 0.0 43.6 41.0 38.9 55.4 38.3 40.9 41.5 43.8 43.9 45.7 45.1 40.8 6.5 12.8 5.1 14.0 2.3 2.0 2.1 3.2 0.0 21.3 4.5 3.7 14.4 8.6 5.4 3.7 14.6 2.5 1.4 5.5 0.0 3.3 1.9 2.4 3.5 5.4 9.0 0.0 22.2 1.8 1.5 4.4 3.6 2.2 8.2 3.0 7.9 5.9 1.0 28.6 19.8 4.2 0.0 2.2 1.3 1.3 6.5 2.2 7.2 14.0 3.9 5.9 3.1 9.5 17.6 2.8 4.4 17.0 1.3 3.7 7.8 4.2 6.1 8.8 0.0 11.2 5.5 2.4 1.3 1.7 4.0 1.8 1.9 2.8 4.0 2.2 IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 12 "B-cells: 72318.1;Plasma cells: 96515.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Group enriched" "Detected in many" 6 "Daudi: 9909.1;U-266/70: 10337.6;U-266/84: 3927.9;U-698: 12154.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" 1025.4 2379.8 13.1 20500.0 13.3 6315.2 11287.7 11.3 33.6 3649.2 26.7 35196.7 24515.5 877.3 474.1 5708.4 1137.6 5995.3 810.4 11.4 16.7 1176.6 1580.5 5824.2 21356.1 25.1 18.2 2214.9 462.9 72.6 101.8 22.2 15.3 843.6 30618.3 4.0 19606.1 2123.2 32.9 250.8 17061.1 1259.7 43.5 26904.1 22740.5 1083.9 13.4 8576.0 2151.1 8.1 63075.6 24817.5 705.0 20.2 17.1 0.0 0.0 0.0 0.0 0.0 103.7 0.0 0.0 0.1 0.0 0.0 0.0 9909.1 15.3 0.0 1.0 22.2 0.0 0.0 0.0 510.2 0.0 30.9 0.0 0.0 0.0 67.8 29.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.8 0.4 0.0 0.0 18.3 83.2 28.8 0.0 0.0 16.7 56.4 1509.5 0.6 0.0 79.6 146.1 19.6 1.5 6.0 0.5 0.5 17.2 66.7 0.0 56.9 24.3 44.0 10337.6 3927.9 12154.4 0.0 28.9 0.0 47.5 55.6 31.6 24.6 11.2 21.7 39143.0 28.3 18.3 46.6 35081.5 15.2 16.8 65.2 24.1 29.1 1735.4 23.7 8567.0 13.1 13.3 11.3 33.6 11.4 16.7 25.1 18.2 15.3 43.5 13.4 20.2 58.6 336.5 1863.8 0.0 72318.1 0.0 189.2 0.0 2.2 0.0 8.8 7.0 5.7 163.0 88.5 0.0 0.0 48.0 452.1 39.8 3.9 0.0 2.8 0.7 0.3 72.8 77.8 1658.9 0.0 0.2 37.3 186.5 64.7 0.4 849.0 15.5 340.2 334.8 8.9 0.0 0.0 35.1 0.0 496.3 0.0 11.0 0.0 64.4 0.0 0.0 26.4 0.0 59.8 0.0 0.0 0.0 25.9 0.4 96515.7 193.2 0.3 45.2 12.4 0.0 0.0 3.7 38.4 0.3 0.2 5.9 0.0 49.4 6505.3 0.1 50.2 1.9 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.2;lymphoid tissue: 17.2;urinary bladder: 5.6" "Cell type enriched" "Detected in some" 24 "Plasma cells: 73.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 247 "memory B-cell: 21.2;naive B-cell: 28.2" "Lineage enriched" "Detected in single" 283 "B-cells: 28.2" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" 0.1 0.2 0.0 2.9 0.0 0.8 2.4 0.0 0.0 0.5 0.0 4.5 3.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.4 1.2 2.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 2.6 0.6 0.0 0.0 2.0 0.2 0.0 3.7 1.5 0.0 0.0 0.9 0.1 0.0 17.2 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 141 "Plasma cells: 6195.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cell line enhanced" "Detected in single" "Daudi: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" 4.8 0.4 0.0 101.2 0.0 34.8 34.3 0.0 0.0 46.6 0.0 85.6 21.7 5.4 0.0 17.9 10.2 2.5 3.5 0.0 0.0 8.1 6.4 39.4 317.6 0.0 0.0 1.0 1.9 0.0 0.4 0.0 0.1 3.1 78.3 0.0 54.2 1.4 0.0 1.1 103.7 6.8 0.0 102.8 20.3 2.7 0.0 29.0 7.2 0.0 223.2 45.9 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.1 0.2 480.8 0.2 0.1 0.5 331.6 0.0 0.0 0.4 0.1 0.1 0.2 0.1 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6195.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 79.1;intestine: 92.0;lymphoid tissue: 165.5" "Cell type enriched" "Detected in some" 249 "Plasma cells: 1994.1" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 327 "memory B-cell: 57.6;naive B-cell: 120.1" "Lineage enriched" "Detected in single" 442 "B-cells: 120.1" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 9000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" 2.4 0.4 0.0 30.2 0.0 15.0 18.9 0.0 0.4 11.0 0.1 92.0 39.0 1.6 0.0 13.8 2.5 79.1 1.3 0.0 0.0 1.7 3.9 10.0 27.5 0.0 0.0 2.5 0.9 0.6 0.1 0.0 0.1 3.6 50.3 0.0 30.3 0.9 0.0 0.2 34.4 1.0 0.3 56.6 26.7 0.4 0.0 9.9 2.7 0.0 165.5 23.5 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 57.6 0.0 0.0 0.1 120.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1994.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGKV1D-17 ENSG00000242766 "Immunoglobulin kappa variable 1D-17" A0A075B6S4 2 90082635-90083291 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 6.8;lymphoid tissue: 12.5;salivary gland: 5.7" "Cell type enriched" "Detected in some" 13 "Plasma cells: 36.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 60 "memory B-cell: 7.7;naive B-cell: 4.1" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 1000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.47e-4)" "unprognostic (4.23e-2)" "unprognostic (2.43e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.19e-1)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-5)" "unprognostic (1.38e-1)" "unprognostic (1.56e-2)" "unprognostic (1.17e-1)" "unprognostic (4.04e-3)" 1.3 0.1 0.1 5.1 0.1 0.9 0.8 0.1 0.2 0.3 0.8 6.8 1.5 0.2 0.0 0.5 0.8 0.6 0.0 0.1 0.1 0.3 0.4 1.5 0.8 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 2.2 0.0 5.7 0.3 0.0 0.4 4.7 0.4 0.1 12.5 2.0 0.0 0.1 0.3 0.5 0.0 4.5 1.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 410 "Plasma cells: 5131.4" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" 2.8 0.5 0.0 3.8 0.1 2.3 8.3 0.0 0.1 3.6 0.1 32.7 1.3 1.4 0.0 4.6 2.7 2.6 0.2 0.2 0.2 4.0 2.2 17.9 6.8 0.0 0.2 0.4 0.5 0.0 0.1 0.0 0.0 1.6 2.0 0.0 73.3 8.6 0.0 0.5 19.1 0.0 0.5 63.0 21.2 0.1 0.0 4.7 3.3 0.2 9.1 16.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5131.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 IGKV1D-37 "IGKV1D37, O4" ENSG00000250036 "Immunoglobulin kappa variable 1D-37 (non-functional)" P0DSN7 2 89884740-89885216 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;stomach 1: 15.0;urinary bladder: 20.1" "Cell type enriched" "Detected in single" 11 "Plasma cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 209 "memory B-cell: 13.6;naive B-cell: 29.1" "Lineage enriched" "Detected in single" 284 "B-cells: 29.1" "Cell line enriched" "Detected in single" 5 "HDLM-2: 2.5" HPA048721 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (2.68e-1)" 0.1 0.0 0.0 4.2 0.0 3.3 2.4 0.0 0.0 0.8 0.0 8.6 12.7 0.1 0.4 2.1 0.2 0.5 0.2 0.4 0.0 0.1 0.4 0.8 4.1 0.0 0.1 0.4 1.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 7.1 0.0 0.2 0.0 6.0 0.2 0.0 6.5 15.0 0.2 0.0 1.1 0.1 0.0 2.5 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV1D-42 ENSG00000211633 "Immunoglobulin kappa variable 1D-42 (non-functional)" A0A075B6H8 2 90190193-90190681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.7;lymphoid tissue: 25.3" "Cell type enriched" "Detected in single" 93 "Plasma cells: 9.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 5.6;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 57 "B-cells: 5.6" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 2.6" HPA048721 Approved "Immunoglobulin genes" NA NA 41000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (8.08e-6)" "unprognostic (4.83e-2)" "unprognostic (2.22e-2)" "unprognostic (2.51e-3)" "unprognostic (1.84e-1)" "unprognostic (2.10e-2)" "unprognostic (1.66e-5)" "unprognostic (1.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (1.39e-1)" 0.1 0.0 0.0 7.6 0.0 6.6 10.8 0.0 0.0 0.8 0.0 18.8 7.5 0.2 0.3 1.4 0.2 1.7 0.1 0.0 0.0 0.0 0.3 2.8 2.6 0.1 0.0 4.1 1.1 0.0 0.0 0.0 0.0 0.1 47.7 0.0 8.5 0.0 0.0 0.1 7.9 0.0 0.0 4.2 13.9 0.0 0.0 0.6 0.3 0.0 25.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.9;lymphoid tissue: 4.8;stomach 1: 3.6" "Cell type enriched" "Detected in some" 86 "Plasma cells: 695.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 152 "memory B-cell: 13.3;naive B-cell: 17.0" "Lineage enriched" "Detected in single" 171 "B-cells: 17.0" "Cell line enriched" "Detected in single" 310 "RPMI-8226: 79.1" HPA048721 Approved "Immunoglobulin genes" NA NA 380000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" 0.2 0.0 0.0 2.8 0.0 1.3 1.4 0.0 0.0 0.0 0.0 2.7 1.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 1.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 2.0 0.2 0.0 0.0 2.9 0.0 0.0 1.8 3.6 0.0 0.0 0.5 0.1 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 79.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 695.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.2;lymphoid tissue: 14.2;salivary gland: 5.6" "Cell type enriched" "Detected in some" 29 "Plasma cells: 338.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 323 "memory B-cell: 32.7;naive B-cell: 31.8" "Lineage enriched" "Detected in single" 328 "B-cells: 32.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 38.3" HPA048721 Approved "Immunoglobulin genes" NA NA 1900000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" 0.5 0.0 0.0 5.3 0.0 0.7 1.2 0.0 0.0 0.6 0.0 4.2 1.6 0.1 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.3 0.3 1.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 2.6 0.0 5.6 0.0 0.0 0.0 2.8 0.0 0.0 8.3 1.9 0.0 0.0 1.2 0.6 0.0 14.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 338.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 272.7;lymphoid tissue: 474.9;urinary bladder: 935.2" "Cell type enriched" "Detected in some" 252 "Plasma cells: 5620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.1" "Lineage enriched" "Detected in single" 482 "B-cells: 48.1" "Cell line enhanced" "Detected in single" "NB-4: 1.3" "Immunoglobulin genes" NA NA 840000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" 13.7 14.6 0.1 65.8 0.1 27.4 91.8 0.0 0.6 11.5 0.4 272.7 250.8 3.2 1.1 82.0 6.6 24.1 14.7 0.2 1.0 7.8 8.6 30.0 131.7 0.6 0.1 6.3 5.6 0.2 0.9 0.2 0.9 5.4 180.6 0.0 219.3 3.3 0.3 3.3 98.5 7.9 1.1 474.9 106.8 1.2 0.2 23.7 11.1 0.0 235.6 935.2 14.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.6 0.2 1.0 0.6 0.1 0.9 1.1 0.2 0.3 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5620.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV2-40 ENSG00000273962 "Immunoglobulin kappa variable 2-40" A0A087WW87 2 89330110-89330429 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8;urinary bladder: 34.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "memory B-cell: 15.4;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 66 "B-cells: 15.4" "Cell line enhanced" "Detected in single" "Daudi: 1.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (3.31e-1)" "unprognostic (1.94e-2)" 0.4 0.1 0.0 9.3 0.0 1.1 6.7 0.0 0.1 10.2 0.0 9.7 42.8 0.9 0.0 10.5 15.5 0.1 0.1 0.0 0.0 0.3 1.4 10.9 0.9 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 1.1 7.1 0.0 5.9 2.0 0.0 0.1 6.2 0.0 0.0 17.8 19.6 0.2 0.0 1.9 1.2 0.1 6.2 34.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.7;lymphoid tissue: 25.5;urinary bladder: 15.3" "Cell type enriched" "Detected in single" 207 "Plasma cells: 165.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Cell line enriched" "Detected in single" 8 "U-937: 1.0" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.21e-4)" "unprognostic (1.78e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.09e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (4.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.74e-5)" "unprognostic (7.60e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (3.47e-1)" 0.6 0.8 0.0 4.3 0.0 2.7 6.1 0.0 0.7 0.5 0.0 16.8 19.7 0.1 0.0 1.5 0.4 3.5 0.1 1.8 0.0 0.6 0.5 1.8 6.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 7.2 0.0 9.6 0.5 0.0 0.3 7.0 0.1 0.1 25.0 5.2 0.1 0.1 1.7 0.4 0.0 25.5 15.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-26 ENSG00000211623 "Immunoglobulin kappa variable 2D-26" A0A0A0MRZ7 2 89985922-89986702 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 245 "memory B-cell: 21.8;naive B-cell: 27.1" "Lineage enriched" "Detected in single" 272 "B-cells: 27.1" "Cell line enriched" "Detected in single" 10 "U-698: 1.0" "Immunoglobulin genes" NA NA 1000000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.11e-1)" "unprognostic (6.09e-2)" 0.0 0.4 0.0 1.5 0.1 0.5 1.0 0.0 0.2 0.1 0.0 4.6 3.5 0.0 0.0 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 0.0 0.0 2.8 0.0 0.0 2.3 1.3 0.0 0.0 0.5 0.0 0.0 6.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960754 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 221.6;lymphoid tissue: 462.7;salivary gland: 259.7" "Cell type enriched" "Detected in some" 98 "Plasma cells: 4332.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 224 "memory B-cell: 3054.0;naive B-cell: 2203.9" "Lineage enriched" "Detected in all" 260 "B-cells: 3054.0" "Cell line enhanced" "Detected in some" "HDLM-2: 5.0;RPMI-8226: 2.0;SCLC-21H: 1.9;SH-SY5Y: 4.3;U-698: 4.4" "Immunoglobulin genes" NA NA 3500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.88e-3)" "unprognostic (2.68e-2)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" 9.9 4.8 0.1 162.1 0.2 23.3 35.2 0.0 1.5 7.6 0.3 203.7 221.6 8.3 1.2 113.5 14.0 26.1 4.8 0.3 0.4 11.5 13.3 40.6 166.6 0.7 0.2 2.8 1.9 0.1 0.9 0.4 0.4 11.1 65.9 0.0 259.7 19.2 0.3 1.4 143.3 8.7 0.2 462.7 186.4 5.7 0.2 40.9 37.8 0.3 192.0 157.9 8.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 5.0 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 0.0 1.9 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.6 1.3 0.0 4.4 0.0 1.1 0.0 11.7 7.8 1.2 1.2 0.5 1.3 3054.0 1.3 0.9 2.0 2203.9 0.2 0.9 2.2 1.0 1.5 1.4 1.3 248.7 0.1 0.2 0.0 1.5 0.3 0.4 0.7 0.2 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.0 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4332.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 31.5 0.0 0.1 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 222 "Plasma cells: 1314.8" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cell line enriched" "Detected in some" 6 "U-698: 51.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" 0.4 0.4 0.0 6.4 0.0 4.3 5.9 0.0 0.1 0.8 0.0 15.3 11.8 0.4 0.0 1.0 0.4 0.8 0.8 0.1 0.1 1.4 0.7 2.8 6.7 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.5 11.2 0.0 13.0 4.6 0.0 1.2 8.5 2.0 0.0 29.3 22.2 0.1 0.0 1.6 0.8 0.0 33.5 5.6 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 51.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 124.9 0.0 0.1 0.1 164.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 19.3 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1314.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852497 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 123.3" "Cell type enriched" "Detected in some" 489 "Plasma cells: 1517.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 30.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 494 "memory B-cell: 134.9;naive B-cell: 96.8" "Lineage enriched" "Detected in single" 575 "B-cells: 134.9" "Cell line enhanced" "Detected in single" "Daudi: 3.7" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-4)" "unprognostic (1.16e-2)" "unprognostic (8.37e-2)" "unprognostic (6.04e-2)" "prognostic favorable (9.78e-7)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (3.59e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" 1.7 1.4 0.0 21.0 0.0 14.8 13.5 0.0 0.1 10.0 0.0 16.6 6.9 3.0 0.0 35.6 14.4 7.7 2.0 0.0 0.0 1.0 2.9 19.5 65.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.6 21.8 0.0 32.3 21.7 0.0 0.0 31.2 1.6 0.0 44.8 38.6 0.4 0.0 26.3 5.7 0.0 123.3 34.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 134.9 0.0 0.0 0.0 96.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1517.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 34 "Plasma cells: 196.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cell line enhanced" "Detected in single" "U-266/70: 2.1" HPA047702 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" 1.3 0.7 0.3 35.9 0.2 8.9 6.4 0.0 0.1 1.7 0.0 38.6 32.2 0.8 0.0 2.4 2.1 2.7 0.5 0.0 0.1 2.1 1.3 12.4 13.0 0.1 0.3 1.5 0.5 0.0 0.1 0.0 0.1 0.7 26.6 0.0 18.8 0.3 0.0 0.1 23.6 0.7 0.2 29.9 27.7 0.2 0.0 4.2 2.3 0.0 58.5 17.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 152.5 0.0 0.0 0.1 146.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 30.2 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 196.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 415 "Plasma cells: 207.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 48.7" HPA047702 Approved "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" 0.1 0.0 0.0 5.5 0.2 1.3 0.1 0.0 0.1 0.2 0.0 4.0 4.6 0.0 0.0 1.9 0.1 1.5 0.0 0.1 0.1 0.0 0.2 0.5 1.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 2.1 0.1 0.0 0.0 4.4 0.0 0.0 3.8 4.4 0.0 0.1 0.2 0.6 0.0 4.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGKV5-2 "B2, IGKV52" ENSG00000211599 "Immunoglobulin kappa variable 5-2" P06315 2 88897232-88897784 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9;lymphoid tissue: 83.1" "Cell type enriched" "Detected in some" 193 "Plasma cells: 1664.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "memory B-cell: 21.4;naive B-cell: 17.2" "Lineage enriched" "Detected in many" 21 "B-cells: 21.4" "Group enriched" "Detected in some" 19 "Daudi: 4.2;HDLM-2: 1.8;RPMI-8226: 2.3" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 4700000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.77e-3)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.37e-1)" "unprognostic (2.26e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.62e-6)" "unprognostic (2.60e-1)" "unprognostic (2.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.85e-2)" 0.9 0.0 0.0 10.3 0.0 6.4 19.6 0.0 0.0 5.3 0.0 23.3 35.9 0.8 0.0 4.0 0.9 0.9 0.1 0.0 0.0 0.9 1.0 6.3 17.3 0.0 0.0 0.4 0.4 0.5 0.0 0.0 0.0 0.6 11.1 0.0 14.9 1.9 0.0 0.5 14.3 0.2 0.0 23.5 15.3 0.0 0.0 3.0 1.0 0.0 83.1 4.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1664.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.3;lymphoid tissue: 141.0" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1715.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 28.8;naive B-cell: 9.8" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cell line enriched" "Detected in some" 6 "U-266/70: 10.5" "Immunoglobulin genes" NA NA 250000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" 2.2 0.4 0.0 41.6 0.0 12.0 37.4 0.0 0.1 3.3 0.0 97.3 38.8 1.8 0.6 8.4 1.9 5.9 0.5 0.0 0.0 2.7 2.6 11.9 64.4 0.2 0.0 2.1 0.8 0.0 0.1 0.0 0.0 1.5 79.3 0.0 43.5 9.0 0.0 0.5 38.5 5.0 0.1 63.8 36.3 0.9 0.0 10.2 3.5 0.0 141.0 37.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1715.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV6D-21 "A10, IGKV6D21" ENSG00000225523 "Immunoglobulin kappa variable 6D-21 (non-functional)" A0A0A0MT36 2 90021567-90022185 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 67.0;lymphoid tissue: 152.7;urinary bladder: 227.3" "Cell type enriched" "Detected in some" 7 "Plasma cells: 234.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 154 "memory B-cell: 14.2;naive B-cell: 16.5" "Lineage enriched" "Detected in single" 166 "B-cells: 16.5" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.95e-4)" "unprognostic (5.47e-3)" "unprognostic (2.85e-3)" "prognostic favorable (5.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (7.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" 1.1 0.4 0.0 17.2 0.0 17.2 11.8 0.0 0.1 5.4 0.0 67.0 38.8 1.6 0.0 22.1 0.8 2.7 2.1 0.2 0.0 1.6 2.4 6.3 19.8 0.6 0.0 1.1 1.1 0.0 0.0 0.0 0.1 0.8 31.8 0.0 21.1 17.3 0.0 1.2 37.8 1.0 0.0 45.3 13.4 3.4 0.0 9.1 1.4 0.0 152.7 227.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 234.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV6D-41 ENSG00000211626 "Immunoglobulin kappa variable 6D-41 (non-functional)" A0A0C4DH26 2 90069662-90070238 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.7;intestine: 3.4;lymphoid tissue: 2.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 3.0;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 49 "B-cells: 4.9" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 32000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.64e-2)" "unprognostic (4.43e-1)" 0.0 1.3 0.0 1.3 0.0 0.0 0.1 0.0 0.0 4.7 0.0 3.4 0.9 0.0 0.0 0.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.2 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 37.3;granulocytes: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cell line enriched" "Detected in many" 5 "U-266/70: 600.3" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" 132.3 163.1 2.2 1208.8 1.9 641.9 903.4 1.7 7.0 190.8 4.4 3038.0 3264.2 63.1 2.1 535.0 113.2 640.0 104.5 1.7 2.2 148.2 114.7 470.6 2372.4 3.9 1.7 135.6 69.8 8.0 13.2 1.9 2.2 71.5 2133.6 0.7 2047.0 124.0 4.9 28.8 1389.9 78.0 2.6 3332.0 2335.3 23.7 2.3 873.2 224.5 0.0 5586.9 1948.8 79.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 1.0 0.0 1.9 0.2 0.0 0.0 6.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 9.1 0.0 0.0 1.1 10.2 2.0 0.0 0.0 2.3 8.9 33.4 0.0 0.0 6.3 11.1 1.4 0.0 0.0 0.0 0.0 0.3 2.5 0.0 1.3 4.3 2.6 600.3 119.9 36.5 0.0 3.5 0.0 4.2 7.7 2.0 3.7 1.7 2.9 5729.2 3.8 2.5 6.0 5821.4 0.9 2.2 7.6 2.8 4.8 5.2 3.4 897.2 2.2 1.9 1.7 7.0 1.7 2.2 3.9 1.7 2.2 2.6 2.3 3.4 0.0 6.4 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Group enriched" "Detected in many" 40 "B-cells: 24632.2;Plasma cells: 18795.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Group enriched" "Detected in many" 190 "RPMI-8226: 62032.1;U-266/70: 102644.1;U-266/84: 83511.6" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" 386.6 782.7 7.7 3871.2 6.2 2741.4 2183.6 4.6 14.9 815.5 11.4 8217.0 9734.6 194.3 207.0 1690.0 231.5 2091.8 318.3 4.6 5.7 301.6 382.3 1442.8 5543.4 11.1 5.0 540.2 112.7 16.8 31.0 7.5 6.6 264.0 5055.4 0.7 5934.2 384.9 8.6 74.2 5290.6 306.2 6.6 7090.0 10849.9 256.0 5.4 2071.4 491.7 0.6 19988.7 6482.1 176.7 10.7 120.6 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 221.4 12.0 0.0 0.0 61.9 0.0 0.0 0.0 30.5 0.0 7.7 0.0 0.0 0.0 19.2 343.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 64.7 0.0 0.0 70.1 27.7 52.3 0.0 0.0 45.3 436.2 62032.1 0.0 0.0 46.7 45.7 5.6 43.0 17.3 0.0 17.7 57.2 11.7 0.0 38.9 23.4 78.2 102644.1 83511.6 298.8 0.7 21.9 0.7 9.9 18.6 5.6 5.8 3.0 5.7 11361.1 5.8 4.5 10.9 10650.3 3.5 4.7 118.0 5.8 8.7 303.3 6.5 2385.6 7.7 6.2 4.6 14.9 4.6 5.7 11.1 5.0 6.6 6.6 5.4 10.7 4.1 32.1 121.0 0.0 24632.2 0.0 0.3 0.0 1.2 0.0 16.1 3.0 3.9 44.3 8.1 0.0 0.0 0.3 8.0 28.0 0.0 0.0 0.0 0.0 0.1 86.3 62.5 222.4 0.0 0.0 0.3 42.5 14.8 0.0 65.6 0.0 222.8 539.9 2.1 0.0 0.0 21.5 0.0 134.5 0.0 0.0 0.0 8.5 0.0 0.0 11.4 0.0 15.5 0.0 0.0 0.0 20.6 0.0 18795.5 0.0 0.0 1.4 1.5 0.0 0.0 0.2 10.2 0.0 0.0 2.8 0.0 0.1 538.6 0.0 23.7 0.0 IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4115.7;lymphoid tissue: 8175.8;stomach 1: 4130.0;urinary bladder: 3726.3" "Group enriched" "Detected in many" 35 "B-cells: 12202.8;Plasma cells: 5357.3;T-cells: 3582.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 34 "memory B-cell: 7254.6;naive B-cell: 6119.2" "Lineage enriched" "Detected in all" 37 "B-cells: 7254.6" "Cell line enriched" "Detected in many" 15 "RPMI-8226: 10741.3" "CAB000050, CAB016533" Supported "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000050: , CAB016533: AB_629719" "prognostic favorable (2.32e-4)" "unprognostic (1.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.54e-2)" "unprognostic (8.41e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.45e-2)" "unprognostic (4.59e-2)" "unprognostic (8.77e-2)" "prognostic favorable (4.58e-4)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.04e-9)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (5.97e-2)" 156.2 550.9 2.6 2377.2 2.7 840.6 1388.6 1.4 9.1 220.4 7.1 4115.7 4046.3 115.2 33.2 508.5 88.0 707.7 63.7 1.3 2.8 178.6 171.7 1081.6 2745.8 7.2 1.4 247.8 47.6 7.0 19.0 3.2 2.0 134.0 2268.4 0.3 2264.0 177.1 5.8 20.7 2373.2 113.9 3.4 4261.5 4130.0 55.4 2.1 426.9 232.0 0.9 8175.8 3726.3 111.5 6.4 0.6 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 60.1 0.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 18.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 338.0 0.0 0.0 10.8 15.0 2.8 0.0 0.0 700.2 9.3 10741.3 0.0 0.0 16.6 25.1 4.4 20.8 0.0 0.0 4.9 0.8 11.1 0.0 6.3 7.2 5.0 88.0 103.4 36.1 1.2 5.3 0.5 6.4 9.1 3.9 6.0 2.0 27.3 7254.6 5.1 3.6 6.9 6119.2 2.6 3.3 60.7 4.3 4.6 195.3 4.7 1415.5 2.6 2.7 1.4 9.1 1.3 2.8 7.2 1.4 2.0 3.4 2.1 6.4 2.0 22.4 97.3 0.0 12202.8 0.0 0.7 0.0 0.0 0.0 5.4 0.5 15.3 8.6 3.7 0.0 0.0 0.2 8.8 5.0 0.0 0.0 0.0 0.0 0.1 7.4 12.2 54.8 0.0 0.0 0.0 22.1 5.6 0.1 47.9 0.0 195.9 127.7 0.2 0.0 0.0 3.5 0.0 23.1 0.0 0.0 0.0 5.6 0.0 0.0 2.0 0.0 2.1 0.0 0.0 0.0 3.1 0.0 5357.3 0.2 0.0 1.1 2.2 0.0 0.0 0.0 4.2 0.0 0.0 0.8 0.0 0.1 3582.0 0.0 6.3 0.9 IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 10 "B-cells: 109.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cell line enriched" "Detected in some" 913 "Karpas-707: 122629.0" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" 5.6 4.7 0.0 27.9 0.0 19.9 15.6 0.0 0.4 5.1 0.0 54.1 88.1 4.4 0.5 8.4 4.3 10.7 1.4 0.0 0.5 2.3 3.5 8.3 40.8 0.3 0.0 2.5 1.7 0.1 0.2 0.0 0.2 4.4 23.1 0.0 70.1 0.6 0.1 0.2 23.1 0.9 0.0 107.7 113.1 0.8 0.1 20.0 5.7 0.0 104.2 19.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 112.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122629.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.7 3.0 0.6 111.2 0.0 47.3 0.3 0.1 0.0 0.0 0.1 0.0 128.8 0.0 0.0 0.1 133.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 25.5 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLL1 "14.1, CD179B, IGL5, IGLL, IGVPB" ENSG00000128322 "Immunoglobulin lambda like polypeptide 1" P15814 22 23573125-23580302 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 70.0;testis: 25.2" "Group enriched" "Detected in some" 6 "Early spermatids: 78.0;Late spermatids: 140.7;Melanocytes: 119.2" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.5;lung cancer: 0.5;stomach cancer: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 12.0;naive B-cell: 14.8" "Lineage enriched" "Detected in many" 11 "B-cells: 14.8" "Cell line enriched" "Detected in some" 32 "REH: 787.7" "HPA051134, HPA071406" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 48000000000 "Cluster 24: B-cells - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA051134: AB_2681356, HPA071406: AB_2686393" "unprognostic (6.21e-2)" "unprognostic (5.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.91e-6)" "unprognostic (1.08e-1)" "unprognostic (5.27e-2)" "unprognostic (6.17e-3)" "unprognostic (5.89e-2)" "unprognostic (9.07e-2)" "unprognostic (1.99e-4)" "unprognostic (2.35e-2)" "unprognostic (5.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.3 0.3 0.3 70.0 0.0 0.3 0.4 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.1 1.4 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.2 25.2 0.2 10.1 0.0 0.0 1.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 14.3 2.6 0.0 0.0 0.0 787.7 0.3 17.3 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.1 6.2 0.0 0.0 0.3 0.3 0.0 0.6 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.8 0.3 0.3 0.3 0.4 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.4 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.9 0.0 78.0 0.2 0.3 0.3 0.0 10.5 0.3 0.0 0.4 0.6 0.0 0.5 0.0 0.2 0.7 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 140.7 1.2 0.4 119.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.0 6.2 0.0 0.0 0.0 1.5 0.3 17.1 0.6 0.0 0.3 0.0 17.9 0.1 0.0 0.2 IGLL5 ENSG00000254709 "Immunoglobulin lambda like polypeptide 5" B9A064 22 22887780-22896111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 408.3;lymphoid tissue: 674.1;stomach 1: 308.1" "Cell type enriched" "Detected in some" 55 "Melanocytes: 93931.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 226 "memory B-cell: 515.9;naive B-cell: 615.5" "Lineage enriched" "Detected in many" 246 "B-cells: 615.5" "Group enriched" "Detected in some" 7 "Daudi: 637.2;U-266/70: 386.4;U-698: 441.1" "Secreted to blood" NA NA 53000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "prognostic favorable (6.10e-4)" "unprognostic (7.64e-3)" "unprognostic (4.33e-2)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "prognostic favorable (3.41e-5)" "unprognostic (1.76e-2)" "unprognostic (2.18e-1)" "unprognostic (7.28e-2)" "unprognostic (1.87e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (5.94e-8)" "unprognostic (1.85e-1)" "unprognostic (4.63e-1)" "unprognostic (8.52e-2)" "unprognostic (6.50e-2)" 16.3 25.1 0.3 164.8 0.2 94.4 139.3 0.1 1.2 32.8 0.4 405.6 408.3 7.8 0.0 50.4 14.7 67.3 11.2 0.1 0.1 17.0 15.9 65.7 308.5 0.4 0.1 18.6 11.0 1.5 1.5 0.2 0.2 8.3 249.4 0.1 279.3 22.2 0.5 2.7 181.5 8.8 0.4 458.8 308.1 4.3 0.2 123.6 26.2 0.2 674.1 223.5 10.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 637.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 3.6 0.9 0.0 0.0 0.6 1.0 0.4 0.0 0.1 0.0 0.0 0.9 1.4 0.0 1.9 0.1 0.2 386.4 68.5 441.1 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.2 515.9 0.2 0.2 0.8 615.5 0.1 0.2 1.0 0.2 0.4 2.5 0.3 68.1 0.3 0.2 0.1 1.2 0.1 0.1 0.4 0.1 0.2 0.4 0.2 0.5 0.0 3.2 30.9 0.0 222.5 108.6 0.0 0.0 0.0 0.0 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 12.7 1.2 5.7 0.0 0.0 0.0 7.7 3.1 0.0 11.4 0.1 1.1 4.2 0.0 0.0 0.0 0.1 0.0 0.8 113.1 3.8 0.0 0.9 93931.2 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 1680.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 93.5 0.0 49.3 0.0 2.4 0.0 IGLON5 LOC402665 ENSG00000142549 "IgLON family member 5" A6NGN9 19 51311848-51330354 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.2;retina: 13.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 24.4;Horizontal cells: 79.1;Inhibitory neurons: 17.6;Spermatogonia: 9.7" "Group enriched" "Detected in many" 5 "glioma: 9.2;ovarian cancer: 3.5;testis cancer: 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 35.0;NTERA-2: 16.0;SH-SY5Y: 23.0;SuSa: 9.9;U-2 OS: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041994 Approved "Secreted in brain" NA NA 15000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA041994: AB_10794641" "unprognostic (2.09e-1)" "unprognostic (5.76e-2)" "unprognostic (1.80e-2)" "unprognostic (8.87e-3)" "unprognostic (2.33e-1)" "unprognostic (2.66e-1)" "unprognostic (3.47e-4)" "unprognostic (6.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.89e-3)" "unprognostic (1.59e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.62e-7)" "unprognostic (1.77e-2)" "unprognostic (9.28e-2)" "unprognostic (1.36e-2)" "unprognostic (1.86e-3)" 1.7 1.7 11.5 0.2 9.0 0.7 0.9 23.4 21.6 0.5 1.1 0.6 0.1 0.1 0.7 4.2 0.1 0.2 0.3 11.7 17.1 0.4 1.9 0.2 0.0 47.2 19.1 1.2 0.2 1.8 1.2 0.4 44.9 0.2 0.0 13.9 0.7 0.7 0.0 0.6 0.3 0.1 16.5 0.1 0.2 8.0 22.2 0.0 0.2 0.0 0.0 0.4 1.2 10.8 0.0 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.6 0.0 0.4 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 16.0 0.2 0.0 0.0 0.0 3.5 0.0 0.1 0.1 23.0 0.0 0.0 0.0 9.9 0.2 2.2 0.0 0.0 6.4 0.1 0.0 0.2 0.3 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.5 9.0 23.4 21.6 11.7 17.1 47.2 19.1 44.9 16.5 22.2 10.8 2.1 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 24.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.9 0.0 0.0 6.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 1.8 0.1 0.3 79.1 17.6 0.0 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.7 0.0 2.5 0.0 5.5 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.9 0.9 9.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV1-50 ENSG00000211645 "Immunoglobulin lambda variable 1-50 (non-functional)" A0A075B6I6 22 22327300-22327814 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.4;lymphoid tissue: 14.7;stomach 1: 20.4" "Cell type enriched" "Detected in single" 2575 "Plasma cells: 1545.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 21 "memory B-cell: 11.0;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 33 "B-cells: 11.0" "Cell line enhanced" "Detected in single" "HEK 293: 1.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-4)" "unprognostic (8.01e-2)" "unprognostic (1.28e-3)" "unprognostic (6.91e-2)" "unprognostic (2.10e-1)" "prognostic favorable (7.08e-4)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (7.38e-2)" "unprognostic (1.58e-4)" "unprognostic (4.89e-3)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" 0.5 0.5 0.1 6.1 0.1 3.3 6.7 1.7 1.9 0.5 0.0 5.4 16.4 0.6 1.2 2.4 0.5 0.8 0.0 0.6 0.0 0.2 0.2 4.4 1.9 0.6 0.0 0.9 0.1 0.1 0.1 0.0 0.6 0.3 4.5 0.7 4.6 0.3 0.4 0.0 9.4 0.2 0.0 3.9 20.4 0.4 0.0 0.6 0.2 0.0 14.7 9.3 0.1 1.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.3 0.5 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.1 0.0 0.3 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 1.7 1.9 0.6 0.0 0.6 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1545.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 17 "Plasma cells: 358.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cell line enhanced" "Detected in single" "TIME: 2.3" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" 3.6 1.9 0.1 96.4 0.3 33.8 121.9 0.1 2.2 2.0 0.8 324.6 294.8 1.5 0.0 22.5 24.3 21.9 12.0 0.1 0.3 2.5 7.0 22.3 64.7 1.4 0.1 2.6 11.6 0.0 0.4 0.4 0.2 6.4 155.1 0.0 253.6 2.3 0.1 1.0 138.9 12.7 0.2 155.3 194.5 0.4 0.1 22.9 2.5 0.0 329.7 21.8 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 60.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 0.3 0.1 2.2 0.1 0.3 1.4 0.1 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV11-55 ENSG00000211641 "Immunoglobulin lambda variable 11-55 (non-functional)" A0A075B6I3 22 22201663-22202161 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Cell type enhanced" "Detected in some" "Late spermatids: 3.5;Plasma cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Daudi: 8.6;U-698: 2.7" "Immunoglobulin genes" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.22e-1)" "unprognostic (6.16e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 210 "Plasma cells: 2488.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Group enriched" "Detected in some" 7 "RPMI-8226: 13.4;U-266/70: 22.3;U-266/84: 7.2" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" 3.4 0.3 0.0 73.0 0.0 23.7 67.1 0.0 0.3 6.7 0.1 271.5 262.0 4.2 0.0 39.6 10.8 36.3 12.5 0.0 0.0 2.0 2.8 12.6 37.6 0.1 0.0 4.1 1.1 2.1 0.2 0.1 0.4 1.7 138.6 0.0 64.3 4.9 0.1 0.3 150.2 6.5 0.0 95.8 72.5 0.5 0.0 22.1 2.8 0.0 224.4 18.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 13.4 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.3 7.2 0.1 0.1 0.1 0.0 0.2 1.8 0.0 1.6 0.0 0.8 321.2 0.3 1.3 0.1 126.9 0.7 0.6 0.5 5.0 0.1 0.2 0.1 69.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2488.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-33 ENSG00000211656 "Immunoglobulin lambda variable 2-33 (non-functional)" A0A075B6J2 22 22588155-22588688 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.3;lymphoid tissue: 2.7;salivary gland: 2.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 2.9;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 30 "B-cells: 2.9" "Group enriched" "Detected in some" 9 "RPMI-8226: 1.5;U-266/70: 5.1;U-266/84: 3.4" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "unprognostic (1.29e-2)" "unprognostic (1.79e-3)" "unprognostic (2.13e-1)" "unprognostic (4.30e-1)" "unprognostic (2.64e-3)" "unprognostic (2.47e-2)" "unprognostic (2.06e-1)" "unprognostic (6.68e-2)" 0.0 0.1 0.0 1.5 0.0 1.3 0.4 0.0 0.0 0.0 0.0 2.2 4.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.6 0.0 0.0 0.0 2.3 0.2 0.0 1.5 1.5 0.0 0.0 0.1 0.0 0.0 2.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 52 "Plasma cells: 1090.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HL-60: 1.0;RH-30: 1.6" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" 33.3 112.9 0.5 144.0 0.4 65.5 111.1 0.1 3.3 41.3 0.6 308.0 176.3 7.6 4.5 56.3 7.9 43.5 20.5 0.1 0.2 12.2 20.8 48.0 230.5 1.8 0.2 14.6 10.8 0.9 0.8 0.4 0.6 11.0 317.0 0.0 139.7 10.8 0.2 8.1 94.9 5.8 0.1 217.1 288.7 97.4 0.2 25.9 8.6 0.0 707.7 140.2 7.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.2 0.0 0.2 548.7 0.1 0.2 0.2 315.0 0.0 0.2 0.3 0.1 0.1 0.3 0.1 43.2 0.5 0.4 0.1 3.3 0.1 0.2 1.8 0.2 0.6 0.1 0.2 0.2 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 7.1 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1090.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.2 0.0 IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.2;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.7;NK-cell: 5.6" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.6;T-cells: 4.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" 0.8 1.2 0.0 3.9 0.0 2.7 1.9 0.0 0.3 0.3 0.1 7.3 5.5 0.5 0.0 1.0 0.6 3.3 0.0 0.0 0.0 0.1 0.5 2.7 15.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 5.1 1.7 0.0 0.2 2.7 0.1 0.0 4.6 8.2 0.9 0.0 3.9 0.2 0.0 30.1 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 1.1 9.2 1.0 4.0 0.0 6.7 0.0 0.2 0.0 5.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 80.3;urinary bladder: 42.9" "Group enriched" "Detected in some" 49 "B-cells: 6.2;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 393 "memory B-cell: 107.2;naive B-cell: 121.2" "Lineage enriched" "Detected in single" 417 "B-cells: 121.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 350000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" 1.5 0.0 0.0 6.9 0.0 6.3 4.9 0.0 0.0 0.7 0.0 10.7 9.9 0.2 0.0 2.5 1.9 1.2 0.6 0.0 0.0 0.7 1.3 4.7 13.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.6 10.8 0.0 10.8 0.0 0.0 0.1 5.2 0.6 0.0 12.8 13.0 0.3 0.0 3.5 0.2 0.0 80.3 42.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 107.2 0.0 0.1 0.1 121.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-22 ENSG00000211661 "Immunoglobulin lambda variable 3-22" A0A075B6J6 22 22704265-22704822 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.6;lymphoid tissue: 9.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 72 "memory B-cell: 6.6;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 1100000000 "Cluster 37: B-cells - Transcription" "Cluster 63: T-cells - Adaptive immune response" "unprognostic (2.00e-1)" "unprognostic (9.93e-3)" "unprognostic (3.73e-1)" 0.0 0.7 0.0 1.0 0.0 1.5 2.6 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.8 0.3 0.0 0.0 1.4 0.0 0.0 1.4 0.8 0.3 0.0 9.5 0.0 0.0 5.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV3-32 ENSG00000211657 "Immunoglobulin lambda variable 3-32 (non-functional)" A0A0A0MS00 22 22594528-22595056 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 14: B-cells - Humoral immune response" "unprognostic (4.68e-2)" "unprognostic (1.31e-1)" "unprognostic (7.93e-2)" 0.0 0.0 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 313.9;stomach 1: 117.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 13.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "memory B-cell: 64.7;naive B-cell: 168.7" "Lineage enriched" "Detected in many" 74 "B-cells: 168.7" "Cell line enriched" "Detected in some" 5 "U-266/70: 41.3" HPA003285 Approved "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" 1.8 23.5 0.1 84.6 0.0 27.8 14.9 0.0 0.1 7.3 0.1 87.1 58.7 2.0 0.0 20.8 1.8 18.6 7.6 0.0 0.0 3.2 6.2 17.1 139.8 0.7 0.0 3.9 2.4 0.2 0.1 0.0 0.1 1.4 64.0 0.0 46.2 3.1 0.1 1.5 60.3 5.2 0.0 64.6 117.3 1.6 0.1 35.0 3.8 0.0 313.9 72.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.1 0.3 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 0.3 0.0 41.3 5.8 0.7 0.0 3.9 0.0 0.0 0.1 0.0 1.2 0.0 2.2 64.7 1.3 1.4 0.0 168.7 0.4 1.8 0.1 0.5 0.1 0.0 0.1 6.5 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 15.7;stomach 1: 28.9" "Cell type enriched" "Detected in some" 23 "Plasma cells: 50.3" "Cancer enhanced" "Detected in many" "lung cancer: 4.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 11.7;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 118 "B-cells: 11.7" "Cell line enriched" "Detected in single" 5 "Daudi: 1.3" "Immunoglobulin genes" NA NA 1600000 "Cluster 37: B-cells - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.22e-2)" "unprognostic (5.51e-3)" "unprognostic (2.71e-1)" "unprognostic (4.37e-4)" "unprognostic (1.87e-1)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" 0.2 0.0 0.0 2.1 0.0 1.4 1.6 0.0 0.0 0.3 0.0 5.1 4.5 0.3 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.1 0.1 1.0 10.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 3.3 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 5.3 28.9 0.2 0.0 1.4 0.4 0.0 15.7 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 152 "Plasma cells: 1125.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 4 "Daudi: 7.8;HEL: 13.3;U-698: 3.9" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" 1.8 1.9 0.0 32.9 0.0 18.1 36.6 0.0 0.2 3.3 0.1 70.7 193.1 1.5 0.0 12.3 1.9 3.4 11.4 0.0 0.0 3.1 3.9 43.5 116.3 0.0 0.0 4.6 1.1 0.4 0.2 0.2 0.1 1.1 73.3 0.0 37.9 0.8 0.1 0.1 86.8 2.1 0.0 80.3 37.7 1.7 0.0 18.3 1.7 0.0 112.0 185.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 3.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.4 0.1 0.0 0.0 48.9 0.0 0.0 0.8 0.0 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1125.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV5-37 ENSG00000211654 "Immunoglobulin lambda variable 5-37" A0A075B6J1 22 22427540-22428035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 24.7;intestine: 10.5;lymphoid tissue: 41.5;salivary gland: 11.5;stomach 1: 16.5" "Group enriched" "Detected in some" 4 "B-cells: 2.5;Late spermatids: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "memory B-cell: 6.1;naive B-cell: 7.0" "Lineage enriched" "Detected in single" 58 "B-cells: 7.0" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 14000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (4.69e-4)" "unprognostic (2.44e-2)" "unprognostic (5.68e-3)" "unprognostic (4.26e-1)" "prognostic favorable (4.71e-4)" "unprognostic (4.97e-2)" "unprognostic (3.56e-2)" "unprognostic (3.15e-1)" "unprognostic (5.34e-6)" "unprognostic (1.66e-1)" "unprognostic (4.32e-1)" "unprognostic (1.25e-1)" 0.7 0.0 0.0 9.5 0.0 1.0 3.2 0.0 0.0 1.8 0.0 10.5 10.1 0.2 0.0 4.2 0.9 24.7 1.1 0.0 0.0 0.9 0.7 3.6 4.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.6 8.0 0.1 11.5 0.0 0.0 0.0 8.8 0.2 0.0 22.7 16.5 1.2 0.0 8.4 0.6 0.0 41.5 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 40.5;intestine: 43.5;lymphoid tissue: 97.5;salivary gland: 49.0" "Cell type enriched" "Detected in some" 116 "Plasma cells: 6697.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 160000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" 2.2 0.3 0.0 0.0 0.0 0.4 5.5 0.0 0.4 3.3 0.0 43.5 0.0 0.7 0.0 40.5 2.0 0.0 0.2 0.0 0.0 2.5 3.1 9.6 0.0 0.1 0.0 0.6 0.6 0.0 0.2 0.0 0.1 1.1 0.2 0.0 49.0 0.0 0.1 0.7 42.1 0.0 0.0 97.5 14.1 0.4 0.0 0.0 4.0 0.0 1.4 14.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 57.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6697.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 IGLV5-48 ENSG00000211647 "Immunoglobulin lambda variable 5-48 (non-functional)" A0A075B6I7 22 22352940-22353433 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 5.5;urinary bladder: 2.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 19.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 5.4;naive B-cell: 6.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.76e-3)" "unprognostic (1.91e-2)" "unprognostic (9.43e-2)" "unprognostic (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-2)" "unprognostic (2.97e-1)" 0.0 0.0 0.0 0.9 0.0 1.3 0.9 0.0 0.6 0.4 0.0 3.3 3.3 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.1 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 1.3 0.2 0.0 5.5 0.7 0.0 0.0 2.5 0.1 0.0 5.3 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV5-52 ENSG00000211643 "Immunoglobulin lambda variable 5-52" A0A0A0MRZ9 22 22318727-22319226 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "B-cells: 1.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 11.7;naive B-cell: 10.3" "Lineage enriched" "Detected in many" 6 "B-cells: 11.7" "Low cell line specificity" "Detected in all" "Immunoglobulin genes" NA NA 1200000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "unprognostic (7.26e-2)" "unprognostic (7.05e-2)" "unprognostic (1.86e-2)" "unprognostic (4.66e-1)" "unprognostic (1.29e-1)" "unprognostic (7.61e-5)" "unprognostic (1.22e-1)" "unprognostic (1.89e-1)" "unprognostic (8.45e-2)" "unprognostic (1.51e-1)" "unprognostic (3.93e-2)" "unprognostic (2.25e-3)" "unprognostic (7.75e-2)" "unprognostic (3.51e-2)" "unprognostic (1.57e-1)" "unprognostic (5.46e-2)" 11.5 10.4 10.7 18.0 11.7 14.6 23.8 16.4 14.1 16.5 13.2 26.6 20.1 28.4 44.2 22.5 22.7 22.5 16.6 11.9 11.1 11.5 9.5 14.9 44.1 9.4 9.4 21.6 8.0 13.9 8.6 11.2 11.0 15.9 23.5 22.5 17.9 15.0 10.1 37.7 15.3 22.3 9.2 21.8 29.2 12.9 10.8 17.7 21.4 15.6 53.5 31.1 6.3 13.9 12.1 7.7 18.8 29.2 22.3 25.1 14.4 7.7 19.0 17.3 22.0 15.6 5.0 38.4 8.5 22.5 10.1 16.9 36.0 25.6 24.0 9.4 27.3 13.4 21.4 14.8 8.7 20.8 22.9 24.0 24.0 19.5 34.5 14.2 35.2 13.9 40.7 3.3 32.3 14.5 7.0 13.9 10.5 22.5 5.7 9.4 9.4 6.4 22.6 16.1 21.2 13.2 9.9 10.6 10.9 15.7 21.0 4.8 21.0 40.9 25.7 4.2 9.0 6.7 21.9 18.2 14.0 15.4 12.2 0.0 1.3 1.9 1.1 0.7 1.3 11.7 1.2 1.3 1.5 10.3 0.8 0.8 0.7 0.7 0.8 1.4 0.6 3.1 10.7 11.7 16.4 14.1 11.9 11.1 9.4 9.4 11.0 9.2 10.8 13.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 57 "Plasma cells: 1304.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Cell line enhanced" "Detected in some" "Daudi: 1.9;RPMI-8226: 1.4;U-698: 1.5" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" 8.0 0.8 0.0 31.2 0.1 15.8 45.7 0.0 0.5 4.9 0.0 161.9 132.8 3.6 0.5 7.9 3.3 22.1 3.5 0.0 0.1 3.1 4.2 13.0 59.0 0.0 0.0 4.1 2.2 0.0 1.0 0.2 0.1 2.3 129.3 0.0 72.5 4.7 0.1 0.5 57.1 17.7 0.0 168.6 115.9 0.5 0.0 31.3 6.4 0.7 238.7 31.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 132.0 0.0 0.0 0.0 54.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.2 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1304.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.2 0.0 IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 180 "Plasma cells: 6758.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cell line enhanced" "Detected in some" "Daudi: 8.0;RPMI-8226: 2.8;U-698: 6.6" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" 15.1 3.8 0.0 59.8 0.3 44.2 171.7 0.1 0.9 4.1 0.1 400.6 162.4 4.4 0.0 43.7 3.0 56.0 5.2 0.0 1.6 5.7 7.7 44.9 82.2 0.4 0.0 9.0 6.2 0.1 0.8 0.1 0.2 2.5 298.6 0.0 107.2 5.2 0.5 0.8 133.1 12.1 0.1 248.1 250.7 0.7 0.2 57.3 8.7 0.0 459.1 444.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.3 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 183.6 0.1 0.0 0.1 82.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 15.2 0.0 0.3 0.1 0.9 0.0 1.6 0.4 0.0 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6758.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 805.8;lymphoid tissue: 984.2" "Cell type enriched" "Detected in some" 4 "B-cells: 25.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Group enriched" "Detected in some" 630 "memory B-cell: 257.8;naive B-cell: 529.3" "Lineage enriched" "Detected in single" 848 "B-cells: 529.3" "Cell line enhanced" "Detected in some" "Daudi: 2.2;RPMI-8226: 3.6;SH-SY5Y: 1.8;U-266/70: 6.6" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 620000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.07e-3)" "unprognostic (2.73e-2)" "prognostic favorable (3.84e-4)" "unprognostic (1.07e-2)" "unprognostic (5.24e-2)" "unprognostic (1.04e-3)" "unprognostic (1.65e-1)" "unprognostic (1.75e-3)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" 9.4 4.9 0.1 125.5 0.2 63.9 78.3 0.1 3.5 43.5 1.0 201.1 805.8 22.7 0.8 10.6 5.6 46.4 11.7 0.1 0.2 5.3 13.7 82.2 257.2 0.2 0.1 9.2 13.4 1.3 0.8 0.0 0.7 10.5 191.0 0.0 108.6 1.0 0.2 4.0 161.6 13.0 0.8 275.7 179.2 3.3 0.1 16.5 11.5 0.0 984.2 247.8 3.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.2 3.6 0.0 0.0 1.0 1.8 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.3 6.6 1.0 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.2 0.1 257.8 0.3 0.0 0.4 529.3 0.0 0.0 0.2 0.1 0.4 0.1 0.2 32.7 0.1 0.2 0.1 3.5 0.1 0.2 0.2 0.1 0.7 0.8 0.1 1.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 20 "Plasma cells: 46.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" 2.4 125.5 0.0 14.7 0.0 9.8 6.1 0.1 0.5 3.3 0.0 33.6 36.5 2.2 0.0 6.0 3.2 1.1 1.2 0.2 0.0 1.2 4.4 43.8 118.0 0.2 0.0 3.3 1.4 0.0 0.1 0.1 0.2 0.9 15.1 0.0 29.7 1.0 0.1 0.1 28.2 0.4 0.0 65.9 46.3 2.0 0.0 14.0 3.4 0.1 97.9 39.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.3 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.1 0.5 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 170.5;Horizontal cells: 60.6;Late spermatids: 34.1;Microglial cells: 61.8;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 44.1;HL-60: 23.3;REH: 17.2;RPMI-8226: 55.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" 3.9 4.0 1.4 0.9 0.7 0.6 6.1 0.3 1.0 0.5 3.2 1.3 0.5 1.4 1.6 2.9 4.3 9.7 4.3 2.8 1.1 0.2 0.3 8.6 1.4 0.1 1.0 17.7 0.7 1.3 1.7 0.7 0.3 0.1 1.3 0.2 5.2 0.2 0.1 1.9 1.2 1.5 0.0 0.9 0.7 0.9 3.6 1.3 1.5 0.5 2.5 2.2 0.3 0.3 0.0 0.1 0.3 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.3 0.3 7.5 44.1 0.0 1.6 23.3 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.2 0.1 55.1 0.1 0.1 1.0 0.0 5.9 0.0 0.0 0.2 0.0 0.2 0.0 0.1 1.1 0.0 0.0 2.4 0.0 0.0 0.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.3 1.0 2.8 1.1 0.1 1.0 0.3 0.0 3.6 0.3 2.0 0.0 0.5 1.0 0.6 2.4 1.2 0.5 2.8 15.8 0.6 0.9 1.6 2.8 6.3 1.8 4.2 21.7 2.7 0.2 0.0 0.1 170.5 11.4 4.0 0.9 6.0 3.4 2.4 1.3 2.9 20.4 0.5 0.5 0.0 0.0 0.0 0.1 1.3 60.6 2.8 0.7 4.1 0.8 3.2 34.1 6.8 2.9 3.6 61.8 1.1 25.6 0.0 0.5 0.7 0.4 0.1 1.2 0.3 0.7 0.0 0.3 12.5 2.4 0.0 0.5 2.2 10.7 7.9 0.8 2.4 30.9 0.6 2.5 0.1 0.2 IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 14.0;intestine: 22.3;stomach 1: 15.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 31.5;Enteroendocrine cells: 49.2;Granulosa cells: 122.4;Intestinal goblet cells: 34.7;Proximal enterocytes: 18.8;Undifferentiated cells: 23.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.8;endometrial cancer: 30.9" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 16.4;OE19: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 23000000 "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.63e-2)" "prognostic favorable (3.67e-6)" "unprognostic (4.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (5.86e-2)" "unprognostic (2.74e-1)" "unprognostic (6.31e-2)" "unprognostic (3.33e-3)" "unprognostic (1.81e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-1)" "unprognostic (1.51e-2)" "unprognostic (2.91e-2)" 0.1 0.0 0.0 2.0 0.0 0.0 0.1 0.1 2.4 4.9 0.0 22.3 12.2 14.0 0.0 0.3 0.9 0.7 0.0 0.0 0.0 2.4 3.5 1.3 0.0 0.3 0.1 0.4 0.0 0.0 0.5 0.1 0.4 2.4 12.4 0.0 0.0 0.7 0.0 0.0 12.9 0.7 0.2 0.0 15.0 0.1 0.1 0.0 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.3 0.1 0.4 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.8 0.0 1.8 0.0 0.0 0.4 31.5 0.0 0.1 0.0 6.0 0.5 0.1 49.2 0.0 0.0 3.3 0.0 0.1 12.2 8.9 0.0 122.4 0.0 0.6 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 14.0 0.0 0.0 1.8 18.8 3.2 0.9 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 23.6 0.3 IL10 "CSIF, IL-10, IL10A, TGIF" ENSG00000136634 "Interleukin 10" P22301 1 206767602-206774541 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.7;lymphoid tissue: 7.7" "Group enriched" "Detected in some" 4 "Hofbauer cells: 28.3;Kupffer cells: 44.4;Langerhans cells: 35.5;Macrophages: 99.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in some" "thalamus: 3.5" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1;intermediate monocyte: 1.8" "Lineage enriched" "Detected in single" 6 "monocytes: 2.1" "Group enriched" "Detected in some" 11 "HMC-1: 14.6;U-266/70: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013120, HPA071391" Approved "Secreted to blood" NA NA 5670 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB013120: , HPA071391: " "unprognostic (3.65e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.63e-3)" "unprognostic (2.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (4.26e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-1)" "unprognostic (4.66e-4)" "unprognostic (7.11e-2)" "unprognostic (1.93e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-2)" 6.7 2.1 0.1 7.7 0.1 3.2 0.7 0.2 0.7 0.8 0.9 1.0 0.8 0.3 0.1 1.5 1.4 3.5 1.1 0.2 0.5 0.2 1.6 1.5 5.7 0.7 0.4 0.4 0.1 0.2 0.4 1.9 0.6 0.4 1.3 0.0 0.2 0.7 0.0 0.1 1.1 3.1 0.5 4.9 0.8 0.8 3.5 2.9 0.2 1.2 2.0 2.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.2 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.1 0.1 0.2 0.7 0.2 0.5 0.7 0.4 0.6 0.5 3.5 1.2 0.5 0.0 1.9 0.0 5.6 1.0 0.4 0.0 0.0 0.2 0.2 0.3 0.3 0.0 1.3 0.0 0.0 0.1 1.3 0.0 0.0 0.0 6.9 0.1 0.2 1.9 0.0 0.4 0.0 0.0 0.1 0.8 1.1 0.2 1.3 0.0 0.7 0.5 28.3 0.0 0.0 0.0 0.0 44.4 35.5 2.9 0.0 99.5 1.8 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.4 0.0 0.9 0.8 0.0 0.2 0.7 1.1 0.1 12.9 0.0 0.0 0.4 IL11 "AGIF, IL-11" ENSG00000095752 "Interleukin 11" P20809 19 55364382-55370463 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Pancreatic endocrine cells: 64.4;Smooth muscle cells: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 50.9;BJ hTERT+: 60.0;HBF TERT88: 39.0;hTEC/SVTERT24-B: 47.9;U-251 MG: 187.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 34800 "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (6.60e-3)" "unprognostic (7.23e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (3.32e-3)" "unprognostic (6.33e-2)" "unprognostic (1.04e-2)" "unprognostic (7.84e-5)" "unprognostic (2.47e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (4.83e-2)" "unprognostic (4.07e-8)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.82e-3)" "unprognostic (3.08e-2)" 0.7 0.2 1.1 3.6 0.6 0.9 0.3 2.2 1.3 0.3 0.3 1.0 0.2 2.9 0.3 1.2 0.2 2.8 0.5 0.6 2.6 4.7 0.2 1.2 0.0 3.3 2.6 0.4 0.3 0.0 4.4 1.1 2.6 2.7 0.1 0.5 0.6 0.6 0.0 1.5 0.5 0.3 1.3 0.3 3.7 1.7 2.9 0.3 0.1 0.0 0.1 2.4 0.5 0.5 2.3 1.4 0.5 0.9 0.0 0.0 0.5 50.9 60.0 26.6 35.2 1.2 1.3 0.7 2.5 5.1 14.4 3.0 0.3 1.4 39.0 2.4 1.7 0.2 4.3 3.8 3.1 0.0 0.3 0.3 1.5 47.9 0.3 12.4 0.0 0.2 0.4 1.8 3.4 1.5 0.1 0.4 1.2 2.1 4.2 0.2 16.9 0.3 0.4 0.5 2.9 2.0 6.8 1.2 1.4 6.8 0.8 0.3 0.7 16.1 20.0 0.2 187.4 1.0 2.5 0.4 33.9 0.4 8.9 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.1 0.6 2.2 1.3 0.6 2.6 3.3 2.6 2.6 1.3 2.9 0.5 0.3 0.0 0.5 0.3 0.3 3.2 0.6 4.4 1.2 1.7 0.4 1.8 1.1 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 12.7 0.9 3.6 1.8 0.5 0.0 0.0 0.6 2.8 1.2 12.7 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.0 0.6 1.8 0.0 1.0 0.2 0.0 0.0 0.1 64.4 1.2 1.5 0.0 1.3 0.0 0.2 0.4 0.6 0.0 0.4 51.8 0.4 1.6 0.5 0.6 0.3 0.2 0.0 0.3 0.9 IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34650702-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 57.8;Late spermatids: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 36.8;HSkMC: 38.2" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652" Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229" "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" 26.6 14.8 20.0 15.5 22.9 13.7 30.2 23.9 23.8 44.6 17.2 58.0 21.7 32.9 12.2 16.3 36.8 19.5 66.4 20.6 20.4 21.9 50.7 22.6 32.0 21.4 21.5 38.0 12.9 29.2 21.8 10.3 20.4 30.3 11.4 18.7 26.1 15.7 30.0 61.3 37.9 19.6 20.8 33.3 26.0 18.3 21.6 16.9 48.0 28.5 21.1 32.2 34.1 22.9 2.5 5.5 11.7 11.7 16.5 28.9 5.5 13.8 19.1 8.8 11.9 2.0 4.6 2.6 3.7 36.8 3.3 5.0 3.4 5.0 3.5 23.8 9.2 7.9 23.4 1.0 8.4 2.7 4.3 38.2 6.1 4.9 1.7 11.9 5.6 16.4 3.3 5.4 11.3 1.6 3.6 18.6 2.5 2.0 3.7 5.6 2.3 2.7 2.9 2.5 3.4 12.3 1.7 3.7 5.3 6.1 10.1 10.2 5.2 4.1 10.0 3.2 0.0 3.7 2.6 1.0 10.9 3.1 20.1 2.1 1.0 0.0 1.4 1.4 2.1 0.8 2.7 2.2 1.3 1.0 2.5 1.8 0.3 1.0 0.3 0.5 1.7 1.7 20.0 22.9 23.9 23.8 20.6 20.4 21.4 21.5 20.4 20.8 21.6 22.9 15.8 3.2 14.3 26.8 2.6 17.5 5.8 3.6 6.2 19.6 6.4 25.1 37.9 1.5 3.6 3.7 14.6 11.3 5.1 3.7 0.0 1.9 18.3 0.7 4.4 15.2 9.1 0.8 4.3 0.7 4.1 42.7 3.1 1.3 0.0 57.8 17.5 32.1 4.6 23.5 9.0 5.0 0.0 3.5 19.6 97.2 11.1 3.6 32.0 4.7 2.6 15.2 6.2 5.0 7.3 0.3 4.3 5.7 2.4 2.9 7.0 2.4 1.4 9.0 0.0 32.9 8.9 4.6 21.6 1.4 14.1 12.4 6.0 12.2 5.2 1.7 IL12A "CLMF, IL-12A, NFSK, NKSF1, p35" ENSG00000168811 "Interleukin 12A" P29459 3 159988835-159996019 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 3.9;Ionocytes: 4.1;Oligodendrocyte precursor cells: 4.0;Respiratory ciliated cells: 6.1;Sertoli cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 8.1;HDLM-2: 13.2;SK-BR-3: 17.6" "Region enhanced" "Detected in single" "cerebral cortex: 2.8" "Not detected" "Not detected" HPA001886 Uncertain "Secreted to blood" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA001886: AB_1079132" "unprognostic (6.23e-2)" "unprognostic (7.82e-5)" "unprognostic (1.25e-1)" "unprognostic (3.10e-2)" "unprognostic (4.22e-1)" "unprognostic (7.18e-2)" "unprognostic (4.18e-5)" "unprognostic (2.22e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (9.57e-10)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (9.61e-2)" 0.3 0.4 0.9 0.6 0.9 1.5 0.7 0.9 2.0 0.2 0.3 0.8 0.5 0.3 0.1 4.1 2.1 0.2 0.8 0.8 0.8 0.4 0.1 2.1 0.8 0.9 1.1 0.5 0.5 0.0 0.5 0.1 1.0 0.3 0.4 0.1 0.3 0.1 0.2 0.1 0.8 0.2 0.7 1.2 0.5 0.3 0.9 0.4 0.2 0.7 0.5 0.7 0.6 1.1 3.1 0.3 0.4 2.6 0.0 0.2 0.2 3.3 2.1 3.9 8.1 1.2 0.1 0.0 0.2 0.5 4.5 0.3 0.8 0.5 3.6 13.2 4.1 0.1 0.2 0.9 2.5 0.7 6.1 0.6 1.0 6.9 2.7 2.7 1.2 0.3 0.0 2.1 2.4 0.1 0.1 0.0 0.4 0.1 1.8 2.4 0.0 0.4 0.4 0.2 0.1 1.2 0.0 17.6 0.5 0.6 0.9 1.4 0.9 0.8 0.8 2.3 6.3 1.4 0.0 0.0 1.5 5.9 0.8 0.0 0.0 0.5 0.3 0.1 0.5 0.5 0.1 0.6 0.0 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.9 0.9 0.9 2.0 0.8 0.8 0.9 1.1 1.0 0.7 0.9 1.1 1.0 0.0 0.6 1.0 3.4 0.1 2.1 1.0 1.2 0.0 1.6 2.2 0.4 0.0 1.1 0.0 0.0 0.1 0.7 0.3 0.0 1.5 0.0 3.9 0.2 1.4 2.4 0.8 0.1 0.0 0.0 0.4 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.0 1.9 0.9 4.1 0.3 0.3 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 4.0 1.3 0.4 0.2 0.0 2.1 2.9 0.1 0.0 6.1 0.0 6.6 1.5 0.3 0.4 2.9 2.6 0.1 0.0 0.7 0.1 0.5 1.3 IL12B "CLMF, CLMF2, IL-12B, NKSF, NKSF2" ENSG00000113302 "Interleukin 12B" P29460 5 159314780-159330487 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in some" 4 "monocytes: 6.7" "Cancer enriched" "Detected in single" 20 "testis cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA040970 Supported "Secreted to blood" NA NA 140000 "Cluster 11: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 3: Monocytes - Immune response regulation" "HPA040970: AB_10796234" "unprognostic (5.96e-5)" "unprognostic (4.59e-5)" "unprognostic (1.05e-1)" "unprognostic (3.40e-1)" "unprognostic (9.13e-4)" "unprognostic (6.89e-2)" "unprognostic (2.58e-4)" "unprognostic (6.69e-3)" "unprognostic (3.83e-2)" "unprognostic (4.50e-2)" "unprognostic (2.53e-1)" "unprognostic (7.15e-3)" "unprognostic (9.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-2)" 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.6 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.4 0.2 0.1 0.1 1.4 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL13 "ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600" ENSG00000169194 "Interleukin 13" P35225 5 132656263-132661110 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 24.3" "Cell type enhanced" "Detected in some" "Early spermatids: 96.7;Late spermatids: 200.7;Spermatocytes: 44.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 187 "HDLM-2: 41.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA042421 Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 40000 "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042421: AB_10795504" "unprognostic (2.17e-1)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.92e-1)" "unprognostic (5.21e-3)" "unprognostic (1.79e-1)" "unprognostic (2.69e-1)" "unprognostic (5.20e-1)" "unprognostic (7.10e-2)" "unprognostic (3.61e-3)" "unprognostic (3.34e-1)" "unprognostic (5.97e-4)" "unprognostic (4.70e-2)" "unprognostic (2.05e-1)" "unprognostic (7.39e-2)" "unprognostic (1.38e-1)" 0.3 0.0 0.1 0.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 96.7 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 200.7 2.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.5 44.4 1.2 0.0 0.6 0.0 14.7 0.0 0.0 0.0 IL15 "IL-15, MGC9721" ENSG00000164136 "Interleukin 15" P40933 4 141636583-141733987 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.0;monocytes: 72.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 17.6;Karpas-707: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004457, HPA037738" Approved Supported "Nucleoplasm,Nuclear speckles" "Secreted to blood" NA NA 182000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear speckles" "CAB004457: AB_2124575, HPA037738: AB_2675640" "unprognostic (1.10e-2)" "unprognostic (1.53e-1)" "unprognostic (1.04e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (5.20e-2)" "unprognostic (1.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.09e-1)" "unprognostic (4.03e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" 7.7 3.4 1.3 7.1 1.4 4.0 6.0 2.1 1.8 5.3 1.4 7.7 6.1 4.5 2.5 4.4 4.5 4.9 5.1 1.2 1.3 7.9 3.6 7.8 9.7 2.3 1.3 1.5 2.7 0.7 3.6 3.1 1.8 4.1 5.3 4.3 3.6 2.7 8.6 3.4 10.0 4.6 1.5 15.4 4.8 2.5 1.8 6.8 15.6 3.4 6.6 4.5 6.4 1.9 2.8 6.3 0.3 0.6 0.9 5.4 1.6 6.7 6.1 6.8 5.5 3.4 8.1 2.5 8.5 6.2 6.0 4.4 0.1 3.4 3.6 17.6 1.7 0.5 16.7 0.5 4.5 1.9 1.3 2.1 1.5 4.4 0.5 13.7 4.3 2.3 4.0 18.8 4.2 0.9 4.2 0.3 3.3 2.3 1.7 1.0 16.0 0.5 9.2 0.8 0.6 1.6 3.1 4.7 3.2 0.8 0.9 0.3 6.6 6.9 4.3 2.0 4.2 13.0 1.8 1.0 7.2 0.8 2.5 10.4 16.1 0.6 2.7 15.1 5.0 4.1 3.3 2.5 5.5 4.0 1.4 1.4 1.2 3.2 16.5 0.2 2.0 6.1 1.3 1.4 2.1 1.8 1.2 1.3 2.3 1.3 1.8 1.5 1.8 1.9 14.8 0.0 2.8 0.3 9.9 6.1 2.5 2.1 2.2 0.6 2.1 1.3 2.9 2.8 5.3 5.5 0.0 1.2 5.0 4.7 0.0 9.4 6.6 6.9 78.0 14.8 0.0 1.3 2.0 14.0 1.6 5.5 4.1 5.9 0.0 0.9 11.4 2.5 4.7 0.0 4.8 5.4 0.0 17.0 22.1 2.5 2.8 16.7 8.8 4.7 72.0 21.1 8.2 3.0 0.2 19.8 8.2 1.2 9.3 6.2 9.9 12.0 3.9 0.9 6.6 7.6 4.0 1.2 0.8 5.6 3.4 0.3 6.0 0.1 2.6 3.0 IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 39.1;Exocrine glandular cells: 55.2;Fibroblasts: 37.6;Hepatic stellate cells: 36.0;monocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 70.8;EFO-21: 41.3;HDLM-2: 78.5;HHSteC: 42.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 8 "cerebellum: 7.1" CAB026215 Approved "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "CAB026215: " "unprognostic (2.86e-2)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (7.87e-2)" "unprognostic (5.49e-2)" "prognostic unfavorable (2.67e-6)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.18e-3)" "prognostic unfavorable (1.27e-12)" "unprognostic (4.43e-2)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (5.75e-2)" 19.3 7.5 3.3 20.4 3.7 11.7 18.3 3.0 4.6 21.5 3.6 12.3 16.2 15.0 4.6 11.5 18.8 23.2 17.8 2.8 4.4 14.1 19.5 44.5 21.3 5.7 3.9 3.7 11.5 2.2 4.6 16.1 4.6 10.4 10.9 0.3 8.0 5.3 7.1 11.2 15.7 12.1 4.8 15.1 16.3 3.2 4.6 5.7 12.1 10.2 11.6 25.7 12.7 3.5 16.8 2.4 0.0 0.7 21.5 4.9 4.3 8.6 18.4 10.7 11.4 0.3 70.8 1.9 41.3 16.0 6.0 15.6 2.0 12.1 2.4 78.5 3.5 2.0 4.9 1.2 42.7 0.9 0.6 4.1 4.2 6.0 0.2 4.4 29.1 1.3 20.5 23.5 0.3 9.3 3.6 8.9 0.4 6.7 6.8 10.0 0.0 13.4 2.8 1.3 0.1 0.1 12.9 1.4 0.6 0.2 6.1 8.0 10.8 0.5 1.3 30.1 11.2 20.5 6.2 0.4 4.9 12.4 0.7 10.2 26.0 6.6 18.9 32.8 29.1 10.8 14.7 19.7 7.1 6.4 6.1 11.0 7.5 11.5 21.0 0.1 17.7 12.8 3.3 3.7 3.0 4.6 2.8 4.4 5.7 3.9 4.6 4.8 4.6 3.5 25.2 6.4 5.0 1.3 6.0 5.7 5.7 9.9 4.6 0.0 4.4 3.0 5.8 22.8 3.3 0.0 0.0 0.6 4.2 5.8 0.0 39.1 1.7 5.1 23.0 21.0 5.4 19.8 3.3 55.2 1.6 37.6 9.7 6.7 3.8 0.1 36.0 8.7 6.6 0.0 0.9 6.8 2.0 14.7 5.5 2.1 5.0 7.3 3.6 12.2 55.0 0.0 4.1 1.0 0.3 35.5 13.3 0.7 22.2 20.1 9.3 0.1 3.4 0.0 0.0 7.1 6.4 0.2 0.4 4.6 6.5 0.1 7.8 0.0 9.3 6.8 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 IL17A "CTLA8, IL-17, IL-17A, IL17" ENSG00000112115 "Interleukin 17A" Q16552 6 52186375-52190638 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in single" 14 "T-cells: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Karpas-707: 2.7;U-266/84: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA052258 Uncertain "Secreted to blood" NA NA 9920 "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA052258: " "unprognostic (5.55e-1)" "unprognostic (2.18e-4)" "unprognostic (3.05e-4)" "unprognostic (1.41e-2)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.2 IL17B "IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7" ENSG00000127743 "Interleukin 17B" Q9UHF5 5 149371324-149404202 "Cancer-related genes, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 44.8;Peritubular cells: 13.2;Sertoli cells: 26.3;Smooth muscle cells: 7.6;Theca cells: 9.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "basophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cell line enhanced" "Detected in some" "HEL: 1.3;Karpas-707: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042441 Uncertain "Secreted to blood" NA NA 75000 "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" "HPA042441: AB_10797014" "unprognostic (2.83e-4)" "unprognostic (2.71e-2)" "unprognostic (4.90e-3)" "unprognostic (9.22e-2)" "unprognostic (7.43e-2)" "unprognostic (5.03e-2)" "unprognostic (9.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (6.54e-2)" "unprognostic (9.30e-3)" "unprognostic (3.22e-1)" "unprognostic (6.98e-8)" "unprognostic (2.66e-1)" "unprognostic (1.53e-1)" "unprognostic (6.47e-2)" "unprognostic (1.10e-1)" 1.4 2.2 0.0 1.0 0.0 0.2 2.9 0.5 0.1 3.2 0.0 3.1 0.3 4.3 0.0 1.5 1.1 0.4 1.1 0.0 0.0 0.7 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 2.4 0.1 0.4 2.8 2.1 0.3 0.9 1.3 2.2 0.0 0.6 0.8 3.7 0.0 0.0 0.1 0.2 0.0 1.4 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.8 44.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.1 0.2 0.6 1.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 1.0 1.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 26.3 0.6 7.6 0.1 0.1 0.0 0.3 0.0 0.0 9.9 0.0 0.1 IL17C "CX2, IL-17C, IL-21, MGC126884, MGC138401" ENSG00000124391 "Interleukin 17C" Q9P0M4 16 88638572-88640468 "Predicted secreted proteins" "Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 2.1;urinary bladder: 1.7" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 210.7;Club cells: 191.2;Ionocytes: 52.9" "Cancer enhanced" "Detected in some" "stomach cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065051 Supported "Secreted to blood" NA NA 30500 "Cluster 71: Testis - DNA repair" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA065051: AB_2685413" "unprognostic (1.60e-1)" "unprognostic (1.69e-1)" "unprognostic (7.31e-2)" "unprognostic (4.45e-1)" "unprognostic (5.58e-2)" "unprognostic (2.93e-2)" "unprognostic (3.50e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-2)" "unprognostic (3.46e-1)" "unprognostic (1.89e-2)" "unprognostic (3.04e-3)" "unprognostic (2.73e-2)" "unprognostic (7.91e-2)" "unprognostic (3.56e-3)" "unprognostic (8.37e-3)" 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 210.7 0.0 0.0 0.1 0.0 0.1 4.3 191.2 0.0 0.0 0.0 1.6 0.7 0.0 0.9 0.0 0.9 0.2 0.1 0.0 0.0 0.0 4.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 52.9 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.3 0.1 21.8 0.0 0.0 0.0 1.3 0.4 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.4 IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 64.0;Early spermatids: 19.3;Excitatory neurons: 17.5;Late spermatids: 35.0;Muller glia cells: 20.2;Oligodendrocyte precursor cells: 20.6" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" 8.4 5.7 71.9 1.6 79.7 0.4 6.4 68.7 58.7 15.2 21.6 5.6 9.4 6.5 1.1 8.9 5.0 5.1 11.6 66.0 70.9 2.6 0.8 6.2 1.2 79.1 62.2 9.3 5.9 0.4 8.9 1.6 61.8 5.5 0.5 10.6 4.3 1.6 131.1 5.4 5.7 1.2 79.6 0.9 4.4 3.9 68.2 0.2 7.6 24.5 0.3 5.4 9.9 79.8 16.5 2.2 3.5 7.6 8.1 4.6 18.3 4.5 1.1 0.4 0.8 7.6 8.7 11.0 0.8 0.4 5.3 8.5 1.5 0.1 0.2 4.0 12.2 0.8 0.7 9.1 1.0 12.2 2.4 6.3 0.1 0.6 0.0 6.9 5.0 15.3 4.5 0.0 3.0 15.9 13.6 10.0 10.7 19.2 2.6 17.8 8.6 1.3 0.2 14.1 20.7 6.7 2.6 3.8 18.3 6.1 9.6 10.4 27.1 1.7 3.0 1.4 5.7 2.0 1.7 2.9 4.0 5.7 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.9 79.7 68.7 58.7 66.0 70.9 79.1 62.2 61.8 79.6 68.2 79.8 0.7 0.0 0.0 64.0 0.2 2.4 0.3 0.0 1.2 1.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 1.1 0.3 0.7 0.0 0.1 19.3 0.2 1.6 0.6 0.0 0.4 17.5 0.2 7.4 7.6 0.0 0.7 0.0 0.9 1.4 0.0 0.4 0.0 12.2 0.1 0.0 0.3 1.9 35.0 11.5 0.2 8.8 2.8 0.0 20.2 0.0 20.6 12.5 0.2 0.1 1.2 0.0 0.5 0.2 0.2 0.0 4.9 0.0 9.4 2.0 8.6 0.6 0.0 2.0 1.1 0.3 0.1 0.3 0.2 IL17F "IL-17F, ML-1, ML1" ENSG00000112116 "Interleukin 17F" Q96PD4 6 52236681-52244500 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 30000 "Cluster 14: B-cells - Humoral immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.40e-1)" "unprognostic (1.20e-1)" "unprognostic (3.02e-1)" "unprognostic (2.52e-1)" 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115694 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.9;Kupffer cells: 81.4;Macrophages: 61.4;monocytes: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HL-60: 59.9;NB-4: 52.5;THP-1: 74.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 62000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" 9.1 5.6 5.5 9.6 11.3 31.8 6.9 5.7 7.5 5.4 6.8 4.7 3.8 5.4 5.0 5.2 6.0 3.6 4.6 6.3 5.5 3.7 5.7 10.0 6.9 9.8 7.3 4.5 5.2 3.9 3.8 3.5 8.9 5.0 3.4 1.5 5.2 2.8 1.8 6.9 6.2 5.3 7.7 16.6 5.6 2.0 7.7 15.4 4.2 2.6 5.6 4.6 4.7 9.6 7.9 4.5 4.1 5.1 8.0 4.6 5.1 11.5 7.4 5.3 6.8 4.4 5.1 7.1 4.6 11.6 6.9 12.4 5.6 5.4 3.7 11.6 6.6 0.0 2.6 2.8 9.2 59.9 17.8 6.8 7.9 4.7 3.7 5.2 5.7 5.6 3.0 7.3 5.5 6.7 7.2 52.5 2.2 10.1 4.3 1.6 0.8 1.3 5.1 5.8 2.8 0.1 8.0 6.7 5.7 4.6 5.3 74.7 15.9 4.1 5.8 6.1 4.3 5.8 3.4 3.3 6.0 28.3 4.5 8.5 7.4 7.2 1.1 3.4 0.9 0.5 1.5 1.2 3.9 0.4 2.4 1.8 16.5 1.5 3.5 1.8 1.0 2.6 5.5 11.3 5.7 7.5 6.3 5.5 9.8 7.3 8.9 7.7 7.7 9.6 14.0 12.8 14.1 2.9 13.8 8.8 6.6 10.2 10.8 3.9 7.2 5.8 6.1 10.0 8.6 5.5 8.4 6.1 18.7 23.6 0.0 8.7 4.0 7.2 8.1 13.7 13.2 9.2 8.3 12.6 11.9 13.6 29.0 9.7 7.6 58.9 17.5 11.1 34.0 3.3 6.4 13.9 6.1 81.4 16.2 2.1 9.0 61.4 8.8 41.2 114.2 4.3 28.8 12.5 11.4 12.2 12.4 4.5 10.3 9.1 14.7 3.4 8.0 2.9 13.1 10.4 10.0 3.0 13.4 9.0 6.8 6.4 25.4 8.1 12.4 9.6 IL18 "IGIF, IL-18, IL-1g, IL1F4" ENSG00000150782 "Interleukin 18" Q14116 11 112143253-112164096 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.5;skin 1: 149.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Basal respiratory cells: 186.4;Basal squamous epithelial cells: 215.1;Kupffer cells: 241.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 117.9;CAPAN-2: 182.3;HaCaT: 167.0;HBEC3-KT: 125.8;hTCEpi: 188.5;PC-3: 110.2;U-2 OS: 208.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003980, CAB007772" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA Yes 196000 16000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Golgi apparatus" Cytosol "CAB007772: AB_562304, HPA003980: AB_1851670" "unprognostic (2.31e-3)" "unprognostic (3.25e-1)" "prognostic favorable (2.78e-4)" "unprognostic (3.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (8.15e-2)" "unprognostic (3.23e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-3)" "unprognostic (4.13e-1)" "unprognostic (3.58e-2)" "unprognostic (1.51e-1)" "unprognostic (3.19e-2)" "unprognostic (3.15e-2)" "unprognostic (9.01e-2)" 19.9 6.1 5.3 18.2 5.4 31.6 12.6 5.9 8.6 38.0 7.0 34.1 22.0 2.4 3.3 124.5 8.0 23.0 3.0 5.3 6.0 23.8 9.1 23.0 67.8 7.5 6.2 1.9 17.9 1.3 2.9 6.7 7.4 6.1 29.1 6.9 15.0 3.0 6.0 149.6 22.0 3.6 6.7 29.3 13.4 1.9 5.7 8.0 3.7 2.1 25.7 25.3 77.0 11.3 117.9 40.0 0.0 0.4 0.0 0.0 0.7 2.0 0.0 0.0 0.1 22.4 182.3 0.1 25.7 0.3 3.2 167.0 0.0 125.8 0.0 0.3 1.2 17.5 35.6 9.9 3.9 9.3 32.6 0.2 188.5 0.3 43.5 0.2 0.1 0.1 0.5 0.3 1.6 0.2 0.2 0.9 0.2 31.9 110.2 0.1 0.1 0.4 79.9 24.8 0.1 0.0 78.4 52.1 0.5 1.0 31.0 25.4 0.3 0.4 208.9 1.2 35.9 0.4 0.3 0.6 0.2 67.1 0.2 6.8 8.7 16.0 0.1 10.9 0.0 0.7 0.1 0.0 25.8 0.7 0.0 0.5 9.5 19.6 6.3 5.6 0.0 2.5 5.3 5.4 5.9 8.6 5.3 6.0 7.5 6.2 7.4 6.7 5.7 11.3 1.0 173.1 38.4 0.7 6.0 122.9 33.5 186.4 215.1 2.6 4.6 7.7 1.0 41.5 66.1 9.2 0.0 2.3 10.8 109.9 80.3 24.7 2.4 94.9 1.4 4.6 14.5 26.3 3.8 143.0 3.7 18.8 20.9 32.5 101.2 2.8 8.2 1.9 68.4 0.0 4.6 30.1 57.0 241.0 37.3 1.9 0.0 123.8 3.6 61.8 38.8 2.7 6.2 2.0 1.1 161.4 104.6 4.5 4.6 23.6 67.5 22.3 69.6 39.1 6.6 0.6 3.9 1.5 1.3 152.6 111.2 1.8 9.6 0.3 47.8 90.5 IL18BP IL18BPa ENSG00000137496 "Interleukin 18 binding protein" O95998 11 71998613-72005715 "Disease related genes, Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Adipocytes: 14.0;Exocrine glandular cells: 13.6;Kupffer cells: 14.2;Langerhans cells: 12.9;Macrophages: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025980, HPA041061" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 3070000 16000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB025980: , HPA041061: AB_2677280" "unprognostic (2.66e-3)" "unprognostic (2.04e-3)" "unprognostic (9.14e-3)" "unprognostic (1.70e-2)" "unprognostic (5.58e-3)" "unprognostic (7.75e-2)" "unprognostic (1.41e-1)" "unprognostic (6.20e-2)" "unprognostic (1.19e-2)" "unprognostic (1.75e-3)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.93e-6)" "unprognostic (1.19e-1)" "unprognostic (4.14e-2)" "unprognostic (6.76e-2)" "unprognostic (1.93e-2)" 14.4 18.4 6.0 25.0 6.3 7.9 13.6 7.1 9.1 12.5 4.9 12.7 8.3 10.4 3.5 6.4 10.1 8.1 10.9 5.8 8.3 24.9 15.0 31.1 26.2 8.7 7.8 11.1 8.4 2.5 10.7 17.1 9.0 16.5 11.0 3.8 8.9 4.2 5.0 7.4 17.2 13.5 6.1 49.2 10.2 6.1 8.5 6.5 12.6 2.4 11.9 12.2 8.5 7.3 1.7 2.3 5.1 2.9 1.0 1.6 5.9 3.3 1.8 3.0 4.0 11.7 2.4 1.2 2.2 1.3 3.4 4.0 2.5 2.4 2.0 2.5 3.8 4.5 7.6 3.7 1.3 2.4 12.3 2.4 2.3 2.4 1.2 3.5 6.3 7.9 7.4 2.0 1.8 3.2 3.8 5.7 3.6 1.9 2.2 6.1 5.4 1.9 2.1 4.4 2.8 5.3 3.0 4.2 3.7 4.8 3.6 2.7 13.6 4.2 3.5 5.1 1.9 3.3 1.8 2.1 1.7 11.5 2.3 7.0 20.2 56.1 52.5 72.9 23.9 31.9 27.5 31.6 36.9 20.2 22.5 32.5 8.6 5.2 60.9 53.7 15.1 39.8 6.0 6.3 7.1 9.1 5.8 8.3 8.7 7.8 9.0 6.1 8.5 7.3 14.0 6.4 3.3 0.7 8.0 2.0 0.4 0.7 0.0 3.3 2.1 1.9 1.8 1.5 1.0 0.0 10.4 1.0 7.2 0.5 0.0 3.0 0.0 1.1 1.9 11.1 0.0 0.8 0.7 13.6 1.4 3.4 1.1 1.8 7.6 2.2 10.4 0.5 11.2 3.3 0.5 0.8 0.0 14.2 12.9 0.0 0.9 15.4 0.0 1.0 4.6 1.1 7.2 0.5 0.0 5.4 0.2 0.7 2.3 1.0 1.1 1.9 1.8 3.7 0.0 1.8 1.6 0.7 0.5 0.6 2.0 0.8 6.4 1.6 0.8 0.2 IL19 "IL-10C, IL-19, MDA1, NG.1, ZMDA1" ENSG00000142224 "Interleukin 19" Q9UHD0 1 206770764-206842979 "Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 20.0;salivary gland: 6.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 11.3;Breast glandular cells: 3.2;Club cells: 9.6;Endometrial ciliated cells: 2.9;Glandular and luminal cells: 5.2;Ionocytes: 4.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "BJ hTERT+: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 172000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (6.21e-2)" "unprognostic (3.84e-2)" "unprognostic (3.55e-1)" "unprognostic (2.17e-2)" "unprognostic (2.48e-5)" "unprognostic (1.07e-1)" "unprognostic (8.72e-3)" "unprognostic (8.42e-2)" "unprognostic (2.04e-3)" "unprognostic (9.17e-2)" "unprognostic (7.20e-2)" "unprognostic (4.91e-2)" "unprognostic (2.78e-1)" 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 20.0 0.0 0.1 0.0 0.3 0.0 1.8 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 6.9 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.2 0.3 0.2 0.1 0.0 0.4 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 11.3 0.0 0.0 3.2 0.0 0.1 0.0 9.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.9 0.7 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 4.1 0.0 1.2 0.2 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 IL1A "IL-1A, IL1, IL1-ALPHA, IL1F1" ENSG00000115008 "Interleukin 1 alpha" P01583 2 112773925-112784493 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.3;testis: 10.4;urinary bladder: 26.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.6;Club cells: 9.8;Endometrial ciliated cells: 11.5;Glandular and luminal cells: 29.4;Macrophages: 30.6;Squamous epithelial cells: 9.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.3;urothelial cancer: 17.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HBEC3-KT: 447.6;hTCEpi: 216.2;hTERT-HME1: 283.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10800 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "unprognostic (3.41e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.99e-2)" "unprognostic (4.28e-2)" "unprognostic (2.08e-1)" "unprognostic (8.03e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-3)" "unprognostic (1.22e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (4.03e-4)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (8.62e-2)" 0.5 0.0 0.3 1.3 0.4 1.0 0.4 0.5 0.4 4.8 0.2 0.3 0.1 2.5 0.8 13.3 0.1 2.3 0.0 0.4 0.5 0.0 0.0 2.3 0.3 0.9 0.8 0.0 0.0 0.4 0.2 1.5 1.0 0.1 0.2 0.1 1.2 0.4 0.0 0.8 0.1 0.0 0.7 0.3 0.1 10.4 0.5 0.3 0.2 0.0 8.7 26.0 1.3 1.2 12.5 0.0 0.5 0.0 0.1 0.0 0.2 0.4 13.5 0.0 0.2 0.5 0.8 0.0 52.5 0.0 65.9 3.6 0.0 447.6 1.7 0.1 0.1 0.1 0.7 0.2 1.0 0.2 0.1 0.0 216.2 3.8 283.4 3.4 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.2 0.2 0.5 0.0 0.0 0.0 0.1 55.0 0.1 0.0 1.6 0.0 0.0 0.6 0.0 0.1 1.7 1.3 0.6 0.3 0.3 0.0 0.1 0.2 5.2 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.4 0.4 0.5 0.9 0.8 1.0 0.7 0.5 1.2 0.9 6.4 1.1 0.0 2.2 1.5 0.7 22.6 1.2 0.0 0.5 0.3 0.2 0.0 9.8 0.0 0.0 0.3 0.3 0.6 0.0 4.6 8.3 11.5 2.8 0.2 0.0 0.0 0.0 0.9 0.1 0.1 0.0 29.4 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.0 0.0 4.8 3.8 0.0 30.6 0.0 5.6 0.0 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.4 0.3 0.0 0.0 1.9 0.0 0.0 0.0 1.1 0.1 0.1 9.4 1.0 0.0 0.4 0.1 0.2 2.4 IL1B "IL-1B, IL1-BETA, IL1F2" ENSG00000125538 "Interleukin 1 beta" P01584 2 112829751-112836816 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 201.7;urinary bladder: 126.2" "Group enriched" "Detected in many" 11 "Langerhans cells: 1451.9;Macrophages: 1510.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 94.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.1" "Cell line enhanced" "Detected in many" "BJ hTERT+: 649.3;HBEC3-KT: 293.3;HMC-1: 235.1;hTEC/SVTERT24-B: 319.1;hTERT-RPE1: 277.0;U-87 MG: 571.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 2330 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "unprognostic (1.55e-3)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.75e-2)" "unprognostic (5.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.12e-2)" "unprognostic (2.63e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-1)" "unprognostic (3.63e-3)" "unprognostic (3.72e-2)" "unprognostic (5.57e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (1.29e-2)" "unprognostic (4.42e-2)" "unprognostic (5.09e-2)" "unprognostic (4.01e-2)" 43.9 7.6 2.5 53.6 2.2 201.7 2.0 3.1 4.6 3.7 4.2 8.1 3.0 7.4 2.0 3.4 4.1 19.0 3.3 2.3 3.4 7.7 9.1 17.4 9.5 4.8 4.6 0.8 4.4 3.0 2.6 7.8 3.8 6.1 6.5 0.3 3.8 1.8 0.1 0.7 3.5 9.2 4.4 17.8 25.5 1.1 2.8 9.4 2.6 7.0 12.8 126.2 1.0 6.6 6.3 0.1 0.2 0.0 0.4 0.0 0.0 2.1 649.3 3.1 6.5 0.0 0.0 0.0 18.0 0.5 11.3 14.7 0.0 293.3 39.2 0.0 0.0 29.5 0.4 0.0 2.2 0.0 235.1 1.1 8.9 319.1 103.5 277.0 0.0 0.1 0.0 0.8 0.6 0.0 0.0 2.9 0.1 1.2 26.2 1.0 0.0 0.0 0.0 48.2 0.0 0.0 1.7 0.0 2.5 0.0 0.0 2.8 0.0 15.3 0.2 0.7 0.5 0.1 0.0 0.2 571.5 14.0 22.7 1.7 12.3 4.4 0.0 19.5 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 94.1 0.2 7.7 0.0 0.0 3.4 2.5 2.2 3.1 4.6 2.3 3.4 4.8 4.6 3.8 4.4 2.8 6.6 23.8 9.6 28.2 0.0 14.1 30.8 5.4 25.4 0.0 0.2 8.2 13.3 4.8 0.0 16.2 1.8 0.0 1.5 7.5 2.8 0.0 33.2 0.3 4.9 5.0 20.0 0.0 58.9 0.0 0.6 2.6 8.1 44.4 8.4 41.7 0.0 1.4 0.4 108.1 0.0 0.0 12.7 14.2 130.5 1451.9 0.7 0.0 1510.7 23.2 1.9 7.9 0.3 0.0 0.0 0.0 2.9 10.0 0.0 9.3 4.7 0.2 0.7 8.6 0.3 0.0 1.5 4.3 0.0 0.4 8.3 20.3 4.4 6.3 0.0 1.9 6.1 IL1F10 "FKSG75, IL-1F10, IL-1HY2, IL1-theta, MGC11983, MGC119832, MGC119833" ENSG00000136697 "Interleukin 1 family member 10" Q8WWZ1 2 113067970-113075843 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skin 1: 12.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 222000 "Cluster 61: Skin - Cornification" "unprognostic (3.89e-1)" "unprognostic (6.25e-2)" "unprognostic (1.48e-1)" "unprognostic (1.18e-1)" "unprognostic (2.42e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 495.7;Kupffer cells: 207.9;Langerhans cells: 1083.3;Macrophages: 210.8;Pancreatic endocrine cells: 211.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 6.4;pons: 1.9" "Immune cell enriched" "Detected in some" 26 "neutrophil: 377.5" "Lineage enriched" "Detected in many" 26 "granulocytes: 377.5" "Cell line enriched" "Detected in some" 8 "HDLM-2: 469.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" NA NA 7130000 27000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" 19.7 5.9 0.2 35.5 0.7 52.8 3.7 0.3 6.4 10.3 1.9 29.7 0.8 2.5 3.5 41.2 17.7 5.3 4.0 0.2 0.5 16.0 11.6 30.8 3.3 0.5 0.4 1.2 3.7 0.3 0.8 20.1 1.9 2.3 43.7 0.1 7.9 2.2 1.2 30.7 4.6 3.4 0.3 90.1 33.0 0.5 0.7 7.4 1.9 2.9 38.5 6.2 20.5 0.3 7.3 0.9 0.0 0.0 0.9 1.2 0.8 0.0 0.2 0.0 0.1 7.7 0.2 0.1 14.7 0.0 0.3 2.9 0.0 0.5 0.0 469.8 0.4 0.1 0.1 4.0 2.5 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 60.4 0.0 0.0 0.0 0.0 24.0 1.7 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.4 0.0 1.1 0.4 7.2 0.2 0.0 0.3 0.0 0.5 0.2 0.0 0.1 4.3 0.0 0.0 2.3 0.0 0.0 0.9 0.0 14.5 0.0 0.0 0.0 377.5 0.2 0.1 0.2 5.9 1.5 0.2 0.7 0.3 6.4 0.2 0.5 0.5 0.4 1.9 0.3 0.7 0.3 1.2 6.4 1.1 0.0 1.7 147.9 13.5 2.0 495.7 0.0 0.5 0.4 0.6 10.0 0.3 1.8 0.0 1.2 1.2 23.8 5.9 15.0 2.8 14.5 1.5 4.4 6.7 2.7 0.0 8.3 36.3 6.1 18.3 8.0 2.5 0.0 3.6 16.2 5.8 0.0 0.0 117.4 0.0 207.9 1083.3 4.0 0.3 210.8 32.0 0.0 3.5 0.0 0.0 0.0 0.0 211.0 26.8 0.0 1.6 20.4 0.0 0.7 2.2 0.0 6.6 0.7 3.8 0.7 2.2 38.1 84.0 27.8 2.7 0.4 26.8 14.4 IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 225.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 109.2;Hepatocytes: 295.8;Oligodendrocyte precursor cells: 298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "eosinophil: 23.8;neutrophil: 95.0" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.0" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 350000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "HPA035293: AB_10671511" "unprognostic (6.48e-2)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "unprognostic (2.35e-2)" "unprognostic (6.60e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.16e-7)" "unprognostic (4.02e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.29e-4)" 6.2 2.9 4.0 11.4 1.1 20.3 4.3 0.0 8.7 4.4 0.5 2.2 1.8 4.0 2.6 13.1 5.4 12.1 3.9 4.6 3.1 3.3 225.8 8.2 2.7 2.4 3.7 3.0 3.9 1.5 1.2 37.0 3.3 3.9 2.2 2.4 5.2 3.4 1.3 11.9 2.2 6.4 1.5 5.4 4.5 1.3 5.5 4.6 4.0 2.1 4.8 9.4 5.5 3.3 13.3 3.0 5.5 0.8 9.5 7.7 10.0 5.8 11.9 13.4 13.2 5.8 29.3 2.2 59.2 16.4 31.1 34.1 3.0 57.6 18.7 2.5 3.6 2.9 5.3 14.5 19.6 20.2 9.5 10.3 23.1 19.7 59.2 27.8 6.0 5.9 0.4 0.2 6.4 6.5 1.7 9.4 8.5 6.0 6.0 9.5 8.2 4.8 5.3 14.8 1.0 0.0 26.3 15.0 247.1 5.2 9.6 14.6 7.9 10.3 10.4 32.1 26.6 5.0 0.2 0.5 17.2 18.0 60.9 11.7 3.8 23.8 1.8 4.3 3.3 2.1 2.1 2.3 3.8 2.1 2.0 1.3 95.0 0.3 6.3 0.6 2.1 1.4 4.0 1.1 0.0 8.7 4.6 3.1 2.4 3.7 3.3 1.5 5.5 3.3 3.5 0.0 14.7 6.5 6.8 44.7 16.5 45.8 68.9 6.5 2.5 4.7 5.5 40.0 22.8 3.7 8.4 8.5 3.6 1.8 0.0 7.7 4.4 8.6 3.8 8.0 5.4 4.4 44.3 7.5 109.2 7.3 7.1 12.3 7.6 0.7 7.5 295.8 7.8 0.0 63.3 1.4 4.1 33.7 17.7 0.6 4.4 28.8 8.8 53.4 5.0 1.0 6.2 298.6 1.5 19.7 0.8 2.6 5.3 11.5 0.7 1.1 8.7 0.6 0.0 18.0 5.1 0.1 0.6 30.9 37.2 24.2 5.2 1.4 1.1 14.3 IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 126.4;lung: 162.0;placenta: 199.8" "Cell type enriched" "Detected in many" 9 "granulocytes: 501.5" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.3;eosinophil: 29.3" "Lineage enriched" "Detected in single" 72 "granulocytes: 38.3" "Group enriched" "Detected in some" 6 "HHSteC: 245.1;HMC-1: 373.7;HUVEC TERT2: 185.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 19100000 3100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" 22.3 30.3 7.5 3.1 9.8 0.7 14.7 7.8 11.0 3.6 12.2 5.2 1.7 2.5 0.6 4.4 2.6 14.7 24.7 7.2 8.2 126.4 16.0 162.0 0.7 7.6 7.7 1.1 4.8 0.8 5.7 199.8 7.7 4.9 3.4 2.8 1.8 4.6 2.5 4.3 8.0 3.7 8.0 1.4 25.1 0.5 9.6 1.3 4.1 0.7 0.8 6.5 3.9 8.9 0.9 0.2 0.7 0.1 15.1 0.6 0.3 0.5 0.7 0.4 0.6 0.3 0.5 0.5 0.7 0.2 0.2 1.4 0.2 6.3 0.4 0.2 0.1 45.7 0.8 0.8 245.1 1.9 373.7 5.1 1.5 6.2 40.0 0.6 185.5 0.2 0.9 0.8 0.7 0.4 0.6 8.7 0.3 0.4 0.7 0.3 0.2 0.2 1.0 0.3 0.6 0.4 0.5 0.3 0.2 0.4 0.3 0.1 15.4 0.5 0.5 3.5 0.5 0.1 0.3 0.4 0.7 0.6 0.5 38.3 0.0 29.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 7.5 9.8 7.8 11.0 7.2 8.2 7.6 7.7 7.7 8.0 9.6 8.9 22.6 9.6 13.1 0.0 0.1 8.5 20.3 0.4 0.0 0.0 0.3 0.1 2.7 0.0 7.7 1.8 0.0 0.0 3.3 0.1 0.0 3.2 0.4 1.1 14.8 49.7 0.0 1.3 0.2 0.5 0.1 54.5 0.0 2.5 501.5 0.0 26.4 0.7 0.0 0.0 0.2 0.0 0.0 0.3 19.1 1.3 0.9 3.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 37.2 0.0 0.0 3.2 15.7 0.0 0.0 6.6 0.3 39.5 1.5 37.7 0.0 0.0 0.0 5.1 0.0 31.5 0.0 0.0 16.4 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IL2 "IL-2, TCGF" ENSG00000109471 "Interleukin 2" P60568 4 122451470-122456725 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Cytokine, Growth factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Melanocytes: 3.6;T-cells: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010310 Uncertain "Secreted to blood" NA NA 20300 "Cluster 7: Non-specific - Mitochondria" "CAB010310: AB_649346" "unprognostic (8.87e-5)" "unprognostic (6.13e-3)" "unprognostic (1.38e-3)" "unprognostic (9.79e-3)" "unprognostic (2.56e-2)" "unprognostic (7.32e-2)" "unprognostic (2.06e-5)" "unprognostic (5.21e-3)" "unprognostic (8.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.4 0.0 0.0 0.0 IL20 "IL-20, IL10D, ZCYTO10" ENSG00000162891 "Interleukin 20" Q9NYY1 1 206865623-206869223 "Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.8;skin 1: 1.1" "Cell type enriched" "Detected in some" 4 "Basal keratinocytes: 69.6" "Cancer enhanced" "Detected in some" "breast cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SiHa: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" CAB025802 Uncertain "Secreted to blood" NA NA 109000 "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "CAB025802: " "unprognostic (3.08e-2)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (1.16e-2)" "unprognostic (6.45e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.46e-1)" "unprognostic (1.60e-1)" "unprognostic (3.38e-2)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" 1.8 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.6 6.6 15.1 0.0 0.0 9.4 3.7 0.1 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 2.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.3 0.0 9.9 0.0 0.1 0.0 0.1 7.3 IL21 "IL-21, Za11" ENSG00000138684 "Interleukin 21" Q9HBE4 4 122610108-122621066 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 5.9" "Group enriched" "Detected in some" 18 "Early spermatids: 13.7;Late spermatids: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 55700 "Cluster 16: Immune cells - Immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.42e-1)" "unprognostic (2.12e-1)" "unprognostic (6.80e-2)" 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.0 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IL22 "IL-21, IL-22, IL-D110, IL-TIF, ILTIF, MGC79382, MGC79384, TIFa, TIFIL-23, zcyto18" ENSG00000127318 "Interleukin 22" Q9GZX6 12 68248242-68253604 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;Langerhans cells: 3.4;T-cells: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 86900 "Cluster 14: B-cells - Humoral immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.57e-1)" "unprognostic (4.24e-2)" 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 2.1 0.0 0.0 0.0 IL22RA2 "CRF2-S1, IL-22BP" ENSG00000164485 "Interleukin 22 receptor subunit alpha 2" Q969J5 6 137143820-137173648 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "breast: 3.6;lymphoid tissue: 3.2" "Group enriched" "Detected in some" 5 "Breast glandular cells: 8.9;Breast myoepithelial cells: 9.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-937: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030582, CAB034906" Uncertain "Secreted to blood" NA NA 40500000 "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" "CAB034906: AB_2124501, HPA030582: AB_10600716" "unprognostic (1.09e-1)" "unprognostic (7.97e-4)" "unprognostic (1.32e-3)" "unprognostic (1.24e-2)" "unprognostic (4.03e-3)" "unprognostic (1.11e-1)" "unprognostic (4.51e-1)" "unprognostic (1.92e-1)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" "unprognostic (7.58e-2)" "unprognostic (1.32e-1)" "unprognostic (1.62e-1)" "unprognostic (6.61e-2)" 0.0 0.0 0.0 1.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 1.1 0.3 0.0 0.0 0.3 0.0 0.0 3.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.1 0.0 0.0 0.0 8.9 9.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 IL23A "IL-23, IL-23A, IL23P19, P19, SGRF" ENSG00000110944 "Interleukin 23 subunit alpha" Q9NPF7 12 56334174-56340410 "FDA approved drug targets, Predicted secreted proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Tissue remodeling" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "urinary bladder: 44.5" "Cell type enhanced" "Detected in many" "Ductal cells: 43.4;Ionocytes: 73.2;Langerhans cells: 151.8;Pancreatic endocrine cells: 70.5;Spermatocytes: 41.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "MAIT T-cell: 14.1;memory B-cell: 18.9;memory CD4 T-cell: 25.7;memory CD8 T-cell: 12.5;naive B-cell: 21.5;naive CD4 T-cell: 28.1;naive CD8 T-cell: 17.6;T-reg: 15.6" "Group enriched" "Detected in many" 12 "B-cells: 21.5;T-cells: 28.1" "Cell line enhanced" "Detected in some" "A-431: 15.3;CAPAN-2: 25.6;U-266/70: 42.1;U-266/84: 20.5" "Region enhanced" "Detected in some" "white matter: 3.9" "Not detected" "Not detected" HPA001554 Approved Approved Cytosol "Secreted to blood" NA NA 11000 "Cluster 30: Non-specific - Translation" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA001554: AB_1079135" "unprognostic (2.34e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.06e-1)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (4.40e-1)" "unprognostic (1.43e-3)" "unprognostic (1.30e-1)" "unprognostic (6.79e-2)" "unprognostic (3.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.03e-10)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (4.50e-3)" 0.6 0.3 0.3 2.1 0.2 3.2 0.3 0.1 0.2 0.4 0.1 0.4 0.2 1.0 0.5 4.5 0.4 0.9 0.3 0.4 0.2 0.6 1.1 1.2 4.2 0.3 0.2 0.3 0.7 0.0 0.6 0.6 0.2 0.5 0.3 0.1 1.3 0.2 0.2 0.7 1.9 0.0 0.2 2.2 0.7 4.4 0.3 7.2 0.4 0.0 8.8 44.5 0.5 0.3 15.3 0.3 0.5 0.5 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.5 25.6 0.9 7.5 0.0 0.8 1.3 0.0 2.5 0.1 1.1 0.5 0.4 0.3 1.2 0.0 0.3 0.9 0.1 0.0 0.0 0.7 3.1 0.0 3.5 0.6 6.2 0.1 0.6 0.6 0.8 2.2 0.3 0.4 0.4 0.2 0.6 8.9 7.4 0.5 0.6 0.3 0.4 1.4 2.1 0.2 7.0 0.5 0.5 0.5 0.4 1.8 42.1 20.5 2.1 0.5 3.7 0.4 0.0 0.4 0.0 2.8 0.0 14.1 18.9 25.7 12.5 0.9 21.5 28.1 17.6 0.2 2.0 0.1 0.1 15.6 10.0 0.3 0.2 0.1 0.2 0.4 0.2 0.3 0.2 0.2 0.2 0.3 0.3 0.5 3.2 2.2 0.0 13.6 3.6 12.1 16.2 0.6 0.0 1.2 1.4 0.4 0.0 23.7 1.8 0.0 0.4 1.5 1.1 1.9 43.4 6.9 11.1 1.0 1.4 0.0 0.0 0.3 7.4 0.5 2.3 1.5 16.6 0.0 0.3 0.0 0.5 2.5 0.0 0.2 1.0 73.2 0.8 151.8 4.2 0.3 14.7 8.8 0.0 34.7 0.5 0.0 0.0 0.3 70.5 0.1 0.7 7.4 6.1 0.4 0.6 15.3 0.5 0.0 0.4 1.4 41.9 6.9 0.6 4.0 0.0 14.4 0.2 2.0 16.3 IL24 "C49A, FISP, IL-24, IL10B, mda-7, Mob-5, ST16" ENSG00000162892 "Interleukin 24" Q13007 1 206897443-206904139 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.2;lymphoid tissue: 25.5;urinary bladder: 14.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.8;Basal prostatic cells: 2.9;Fibroblasts: 11.6;Smooth muscle cells: 7.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 9.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 5.4;T-cells: 3.6" "Cell line enriched" "Detected in some" 9 "BJ hTERT+: 172.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB025972 Uncertain "Secreted to blood" NA NA 140000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB025972: " "prognostic favorable (5.09e-4)" "unprognostic (3.79e-1)" "unprognostic (2.89e-2)" "unprognostic (4.09e-3)" "unprognostic (3.98e-1)" "unprognostic (2.68e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-2)" "unprognostic (3.98e-1)" "unprognostic (3.35e-2)" "unprognostic (8.04e-2)" "unprognostic (7.63e-2)" "unprognostic (3.43e-4)" "unprognostic (5.41e-2)" "unprognostic (1.29e-1)" "unprognostic (7.91e-2)" "unprognostic (3.33e-2)" 3.5 0.1 0.1 3.6 0.1 1.5 0.7 0.1 0.2 0.4 0.2 1.3 0.0 1.0 0.0 0.9 1.0 1.3 0.8 0.1 0.3 0.8 1.2 1.8 5.8 0.2 0.4 0.2 0.2 0.0 0.5 0.9 0.3 1.0 0.0 0.0 1.1 0.0 3.8 0.2 15.2 0.1 0.1 25.5 0.6 0.1 0.3 0.0 1.0 0.0 0.2 14.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 172.7 0.0 0.4 0.0 0.5 0.2 0.1 0.0 3.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.2 2.5 18.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 16.7 0.7 0.0 0.0 0.0 2.3 1.2 7.4 0.5 2.5 0.8 0.3 1.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.9 5.4 1.7 2.7 0.0 5.0 3.6 2.9 0.4 0.4 0.0 0.0 1.9 0.8 0.1 0.1 0.1 0.2 0.1 0.3 0.2 0.4 0.3 0.1 0.3 0.1 0.2 0.0 1.3 0.0 1.8 6.8 2.9 0.5 0.0 0.0 0.4 0.3 1.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.1 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 7.9 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.1 0.7 IL25 "IL-17E, IL-25, IL17E" ENSG00000166090 "Interleukin 25" Q9H293 14 23372809-23376403 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 22 "Cardiomyocytes: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB024864 Uncertain "Secreted to blood" NA NA 4230000 "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB024864: " "unprognostic (1.49e-1)" "unprognostic (6.82e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 IL26 "AK155, IL-26" ENSG00000111536 "Interleukin 26" Q9NPH9 12 68201349-68225810 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.6;T-cells: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HDLM-2: 13.5" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 35700 "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (2.71e-1)" "unprognostic (8.87e-2)" "unprognostic (3.26e-5)" "unprognostic (7.10e-2)" "unprognostic (5.90e-2)" "unprognostic (2.96e-1)" "unprognostic (3.69e-5)" "unprognostic (3.80e-1)" "unprognostic (5.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.79e-2)" 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.8 0.1 0.0 0.0 IL27 "IL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28" ENSG00000197272 "Interleukin 27" Q8NEV9 16 28499362-28512051 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antiviral protein, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 26.7" "Group enriched" "Detected in some" 5 "Hepatocytes: 18.1;Syncytiotrophoblasts: 23.1" "Cancer enriched" "Detected in some" 8 "liver cancer: 4.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;intermediate monocyte: 3.8" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 11 "BEWO: 17.9" "Not detected" "Not detected" "Not detected" "Not detected" CAB024722 Approved "Secreted to blood" NA NA 521000 "Cluster 7: Monocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB024722: " "unprognostic (4.79e-3)" "unprognostic (2.66e-3)" "unprognostic (4.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.09e-1)" "unprognostic (6.55e-3)" "prognostic favorable (1.30e-4)" "unprognostic (3.76e-2)" "unprognostic (8.23e-3)" "unprognostic (1.29e-2)" "unprognostic (6.07e-3)" "unprognostic (4.57e-2)" "unprognostic (2.41e-7)" "unprognostic (6.44e-2)" "unprognostic (1.04e-3)" "unprognostic (2.13e-1)" "unprognostic (2.83e-2)" 0.2 0.2 0.2 1.2 0.1 0.9 0.1 0.3 0.4 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.1 26.7 0.5 0.4 0.4 0.4 0.0 0.1 0.0 0.1 0.7 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 1.7 0.1 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 3.6 0.8 0.0 3.8 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 2.1 1.5 0.1 0.0 0.2 1.0 0.2 0.1 0.3 0.4 0.3 0.2 0.4 0.4 0.2 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 3.1 0.0 0.0 0.1 0.0 0.0 0.0 18.1 0.9 0.0 0.4 0.0 0.0 3.5 1.2 0.1 0.0 2.3 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.1 0.0 0.0 0.0 IL3 "IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF" ENSG00000164399 "Interleukin 3" P08700 5 132060655-132063204 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "HMC-1: 2.8" "Not detected" "Not detected" "Secreted to blood" NA NA 17800 "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (9.74e-2)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IL31 IL-31 ENSG00000204671 "Interleukin 31" Q6EBC2 12 122172029-122174221 "Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Early spermatids: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025657 Uncertain "Secreted to blood" NA NA 37800 "Cluster 34: Spermatids - Unknown function" "CAB025657: " "unprognostic (1.70e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL32 "NK4, TAIF, TAIFb, TAIFd" ENSG00000008517 "Interleukin 32" P24001 16 3065297-3082192 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 829.3;pancreas: 674.4" "Cell type enhanced" "Detected in many" "Ductal cells: 1696.0;Exocrine glandular cells: 1490.0;Pancreatic endocrine cells: 2546.1;Proximal enterocytes: 4916.6;Proximal tubular cells: 4315.8;T-cells: 1711.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 4625.7" "Lineage enriched" "Detected in all" 8 "T-cells: 4625.7" "Cell line enhanced" "Detected in many" "CACO-2: 514.7;CAPAN-2: 328.6;HDLM-2: 707.9;Hep G2: 504.3;Karpas-707: 404.6;MOLT-4: 319.9;RH-30: 348.0;U-937: 314.5" "HPA029397, CAB030029" Uncertain "Secreted to blood" NA NA 46100 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB030029: AB_1089175, HPA029397: AB_10612120" "unprognostic (2.00e-2)" "unprognostic (2.89e-2)" "unprognostic (2.86e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.95e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.73e-3)" "unprognostic (2.19e-2)" "unprognostic (3.32e-3)" "unprognostic (3.51e-1)" "unprognostic (3.30e-2)" "unprognostic (8.08e-2)" "unprognostic (3.86e-2)" "unprognostic (3.16e-2)" "unprognostic (4.29e-3)" 91.1 36.7 21.3 206.7 21.0 49.1 58.7 20.3 27.6 19.2 19.0 206.5 339.8 30.4 13.5 45.5 20.6 117.4 180.6 19.1 20.0 418.8 829.3 271.5 402.7 24.0 20.4 22.3 674.4 10.2 17.7 62.8 23.0 54.2 142.7 1.0 87.1 42.2 543.7 26.9 558.9 88.4 21.2 440.7 87.4 19.2 24.8 198.0 84.3 328.6 200.2 118.8 23.1 21.3 254.1 10.7 1.2 0.3 0.5 28.4 19.5 12.4 31.3 14.9 24.8 514.7 328.6 0.6 59.8 7.0 92.1 10.7 1.0 29.6 18.0 707.9 2.7 1.2 49.8 504.3 55.7 1.4 20.5 34.2 3.4 12.9 54.9 12.1 60.0 7.9 0.7 404.6 19.5 1.7 319.9 8.2 7.2 3.2 7.6 0.7 348.0 34.4 239.3 16.7 0.7 3.9 109.9 7.4 1.9 50.9 7.2 4.0 161.6 56.9 67.2 3.1 36.5 4.7 10.7 1.6 1.1 314.5 29.7 30.8 10.9 12.7 2570.7 9.1 2584.2 9.3 2337.1 2483.4 9.2 7.8 884.8 1712.5 46.9 553.7 11.3 13.4 4625.7 2238.1 21.3 21.0 20.3 27.6 19.1 20.0 24.0 20.4 23.0 21.2 24.8 21.3 334.4 198.7 64.9 0.0 81.7 59.5 68.0 462.2 12.0 0.4 50.3 44.3 5.6 221.6 119.6 119.5 0.0 9.0 550.3 1038.3 252.4 1696.0 0.2 46.5 36.7 286.4 135.1 64.6 0.1 1490.0 14.1 136.7 118.3 53.7 52.6 1.5 68.6 124.1 4.2 0.0 0.1 273.1 244.1 40.5 116.1 1.9 35.1 60.7 65.8 5.6 225.8 0.0 518.0 0.0 0.1 2546.1 1004.5 45.9 81.7 101.2 4916.6 4315.8 55.1 0.6 19.7 278.5 117.4 5.8 1.3 7.1 51.6 6.6 1711.8 27.8 182.2 105.7 IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 120.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 141.8;Fibroblasts: 87.5;Hepatic stellate cells: 499.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 53.6;U-2197: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: AB_1845820" "prognostic favorable (4.42e-4)" "unprognostic (8.36e-2)" "unprognostic (5.67e-3)" "unprognostic (7.67e-3)" "unprognostic (4.27e-1)" "unprognostic (1.63e-1)" "unprognostic (2.59e-3)" "unprognostic (2.66e-3)" "unprognostic (3.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.58e-3)" "unprognostic (4.70e-3)" "unprognostic (4.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.85e-3)" 38.7 16.7 9.2 44.6 9.3 0.2 27.2 7.0 12.1 56.2 6.4 24.8 8.8 50.0 15.9 24.5 25.9 33.4 40.9 8.5 10.8 5.0 36.7 53.0 47.1 7.8 8.3 5.0 3.4 3.7 5.7 61.1 7.1 30.0 19.4 2.0 18.9 31.5 6.1 44.0 15.6 50.8 8.3 20.5 33.6 5.8 10.8 13.1 12.6 13.8 43.0 120.7 21.2 8.6 0.0 0.0 0.0 0.0 0.3 1.4 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.1 16.9 0.3 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.7 0.3 0.4 53.6 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 162.9 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 9.3 7.0 12.1 8.5 10.8 7.8 8.3 7.1 8.3 10.8 8.6 63.5 6.4 7.2 39.5 1.0 24.2 17.0 73.9 27.3 0.0 9.4 4.1 5.8 4.3 77.8 0.0 0.0 0.0 0.1 2.2 0.0 3.0 0.5 12.4 7.1 141.8 10.7 8.0 0.2 7.9 0.0 87.5 48.4 20.6 1.3 0.0 499.4 5.0 0.1 0.0 0.1 0.2 2.0 20.8 10.2 1.6 20.5 1.7 1.8 1.0 0.0 9.5 0.0 0.5 0.1 12.1 0.2 12.4 0.2 5.2 0.0 0.0 62.1 0.1 0.0 65.5 11.5 0.0 0.4 3.3 48.4 0.1 1.2 0.1 1.1 4.9 IL34 "C16orf77, IL-34, MGC34647" ENSG00000157368 "Interleukin 34" Q6ZMJ4 16 70579895-70660682 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.3;skin 1: 62.0" "Cell type enhanced" "Detected in many" "Leydig cells: 18.3;Peritubular cells: 40.6;Sertoli cells: 19.7;Suprabasal keratinocytes: 20.5;Theca cells: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "eosinophil: 18.5" "Lineage enriched" "Detected in single" 185 "granulocytes: 18.5" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.1;Hep G2: 2.7;HSkMC: 2.4;NTERA-2: 5.3;U-138 MG: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 57100 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (3.76e-3)" "prognostic favorable (7.41e-4)" "unprognostic (5.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-2)" "prognostic favorable (9.69e-4)" "unprognostic (8.19e-2)" "unprognostic (1.59e-3)" "unprognostic (3.83e-2)" "unprognostic (6.11e-3)" "unprognostic (3.18e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.52e-8)" "unprognostic (6.47e-3)" "unprognostic (4.58e-2)" "unprognostic (5.83e-2)" "unprognostic (4.37e-2)" 4.4 22.9 17.1 3.9 18.1 0.1 8.6 8.5 23.3 9.6 23.1 4.0 5.1 2.9 1.0 25.5 3.2 6.7 4.4 22.5 14.5 5.7 2.5 5.0 9.1 13.0 11.7 1.6 1.9 1.0 12.5 0.5 14.1 6.2 2.2 1.2 16.0 3.8 9.6 62.0 6.4 2.5 10.1 106.3 2.4 3.5 19.0 3.9 5.1 2.5 5.0 4.8 13.4 11.6 0.0 0.6 0.1 0.1 0.2 2.1 0.2 0.1 1.8 0.2 0.2 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.9 0.0 1.6 2.4 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.3 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.3 0.0 0.0 0.0 3.6 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.7 0.1 1.4 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 18.1 8.5 23.3 22.5 14.5 13.0 11.7 14.1 10.1 19.0 11.6 2.8 0.0 1.8 2.9 0.1 8.3 1.6 3.4 2.2 1.2 15.7 14.7 0.4 1.5 4.9 0.0 4.2 0.1 0.5 0.0 0.0 7.4 0.2 0.5 0.3 6.1 0.0 0.0 12.7 2.0 0.9 9.0 0.0 0.1 0.0 0.0 3.6 0.1 3.8 5.0 11.4 0.1 2.0 0.0 4.2 0.3 18.3 0.4 12.4 5.6 0.0 15.2 0.0 1.5 1.0 0.8 0.1 40.6 0.1 2.4 0.2 0.3 1.2 0.8 19.7 2.0 8.1 0.1 0.4 7.8 20.5 0.8 0.3 18.8 0.5 1.9 IL36A "FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553" ENSG00000136694 "Interleukin 36 alpha" Q9UHA7 2 113005459-113008044 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "esophagus: 411.3;lymphoid tissue: 115.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.2;MOLT-4: 1.2;U-266/70: 1.2" "Not detected" "Not detected" "Secreted to blood" NA NA 327000 "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (1.37e-1)" "unprognostic (9.66e-3)" "unprognostic (5.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.1 0.0 411.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 115.4 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.2;lymphoid tissue: 3.8;skin 1: 8.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "GAMG: 71.8;U-87 MG: 73.3" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" NA NA 15300 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "HPA035664: AB_10669672" "unprognostic (8.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.77e-2)" "unprognostic (2.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.10e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 1.4 0.0 0.0 0.0 0.0 73.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 14.3;lymphoid tissue: 39.4;skin 1: 31.3" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 136.0;Club cells: 36.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 36.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.1;HaCaT: 1.0" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (1.56e-2)" "unprognostic (2.88e-1)" "unprognostic (7.27e-2)" "unprognostic (3.15e-2)" "unprognostic (4.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (5.79e-2)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.9 0.2 0.0 31.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 39.4 0.8 3.6 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 136.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.7 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.0 0.0 1.3 0.2 0.0 1.7 13.2 0.0 0.0 0.0 0.0 7.8 IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 26.5;lymphoid tissue: 43.7;skin 1: 60.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.9;Extravillous trophoblasts: 2.0;Syncytiotrophoblasts: 3.8" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 25.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BEWO: 26.6;GAMG: 11.1;U-87 MG: 19.9" "Not detected" "Not detected" "Secreted to blood" NA NA 107000 "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (3.88e-3)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (4.29e-1)" "unprognostic (8.68e-3)" "unprognostic (9.80e-2)" "unprognostic (2.48e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (5.37e-2)" "unprognostic (3.85e-3)" "unprognostic (4.23e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 3.4 0.0 0.0 0.0 0.0 4.6 0.0 0.1 60.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 43.7 0.0 9.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.1 1.1 0.3 0.0 0.0 11.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.0 0.0 0.0 0.7 IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112912971-112918882 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 136.8" "Cell type enriched" "Detected in some" 26 "Ionocytes: 73.2" "Cancer enriched" "Detected in some" 6 "lung cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.7;PC-3: 5.9;RT4: 3.2" "HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA 76700 "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "HPA054371: AB_2682465, HPA057950: AB_2683561" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.71e-5)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (9.54e-2)" "unprognostic (8.26e-3)" "unprognostic (3.95e-2)" "unprognostic (1.66e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-2)" 0.1 0.0 0.0 0.2 0.0 0.2 16.7 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 0.4 136.8 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.1 0.2 2.7 0.2 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.4 0.8 0.1 0.0 1.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.2 0.2 5.9 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 73.2 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 2.8 0.0 0.1 0.0 0.0 0.0 IL4 "BCGF-1, BCGF1, BSF1, IL-4, MGC79402" ENSG00000113520 "Interleukin 4" P05112 5 132673986-132682678 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "B-cell activation" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "T-cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 861 "basophil: 474.9" "Lineage enriched" "Detected in single" 861 "granulocytes: 474.9" "Cell line enriched" "Detected in some" 5 "MOLT-4: 21.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA072995, CAB078477" Approved "Secreted to blood" NA NA 13600 "Cluster 38: Basophils - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB078477: AB_417057, HPA072995: AB_2732215" "unprognostic (3.40e-2)" "unprognostic (9.19e-2)" "unprognostic (1.41e-1)" "unprognostic (2.49e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.69e-1)" "unprognostic (7.33e-2)" "unprognostic (2.26e-2)" "unprognostic (1.96e-1)" "unprognostic (1.47e-10)" "unprognostic (9.21e-3)" "unprognostic (2.88e-1)" "unprognostic (4.93e-2)" "unprognostic (1.24e-2)" 0.1 0.3 0.1 0.4 0.1 0.3 0.1 0.5 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.3 0.3 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.5 0.3 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 474.9 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.3 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 IL4I1 FIG1 ENSG00000104951 "Interleukin 4 induced 1" Q96RQ9 19 49889654-49929539 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 18.3;testis: 26.8" "Group enriched" "Detected in many" 5 "Langerhans cells: 295.1;monocytes: 682.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 35.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 103.4" "Group enriched" "Detected in many" 6 "monocytes: 36.8;T-cells: 103.4" "Cell line enhanced" "Detected in many" "EFO-21: 34.3;HDLM-2: 62.4;Karpas-707: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045598 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cytosol" "HPA045598: AB_10969138" "unprognostic (6.23e-2)" "unprognostic (1.32e-2)" "unprognostic (8.39e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.61e-2)" "unprognostic (3.74e-3)" "unprognostic (7.03e-2)" "unprognostic (2.52e-2)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.23e-10)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (6.44e-2)" "unprognostic (2.11e-3)" 1.6 0.6 0.4 18.3 0.6 4.2 0.9 0.8 0.6 1.1 0.7 1.7 4.1 1.6 0.2 0.6 3.9 2.0 0.5 0.6 0.5 4.8 1.2 2.4 9.3 1.7 0.9 0.4 0.7 0.2 0.6 1.9 1.8 0.8 1.4 0.1 0.9 0.5 0.3 1.3 2.7 1.5 1.0 4.1 3.1 26.8 1.2 3.4 0.5 0.2 6.7 4.5 0.5 2.3 1.0 1.2 0.8 0.7 0.0 0.8 0.3 0.5 2.0 1.4 2.1 0.7 1.9 3.5 34.3 0.4 2.9 0.5 0.4 0.0 0.2 62.4 0.2 1.6 0.1 0.5 0.1 1.2 12.3 1.0 0.4 0.6 0.1 0.4 2.6 0.4 0.4 47.3 0.1 0.4 0.7 2.1 0.4 0.9 0.1 1.0 0.9 3.6 2.5 3.2 0.7 0.8 0.5 0.9 0.5 0.2 0.4 2.8 2.9 7.1 1.0 0.1 1.0 4.1 9.7 2.0 1.0 0.5 0.7 0.3 22.0 0.3 6.4 36.8 103.4 0.4 13.2 11.5 11.6 0.2 0.3 0.1 0.5 1.3 5.3 1.3 0.7 8.8 0.4 0.6 0.8 0.6 0.6 0.5 1.7 0.9 1.8 1.0 1.2 2.3 0.8 0.0 0.0 0.0 3.6 9.7 0.6 9.8 0.0 0.1 1.2 1.3 0.5 0.0 5.5 3.7 0.0 0.4 1.0 0.2 0.0 3.5 75.4 2.9 0.6 6.7 0.0 0.0 0.4 4.0 0.7 1.3 0.5 2.1 1.3 0.1 1.1 0.2 97.4 0.0 0.4 0.3 6.1 3.0 295.1 18.4 0.3 38.8 3.6 1.9 682.5 0.1 1.0 0.0 0.4 0.5 0.1 0.4 0.7 1.4 0.3 2.7 1.6 0.2 0.0 0.2 2.5 45.2 3.6 0.4 8.2 0.8 6.3 0.0 0.2 2.1 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 IL5 "EDF, IL-5, TRF" ENSG00000113525 "Interleukin 5" P05113 5 132541445-132556838 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;testis: 5.1" "Cell type enriched" "Detected in some" 7 "Spermatocytes: 19.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 1.4" "Lineage enriched" "Detected in single" 8 "B-cells: 1.4" "Cell line enhanced" "Detected in some" "Hep G2: 2.8;TIME: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB010304 Approved "Secreted to blood" NA NA 4130 "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB010304: AB_2296159" "unprognostic (1.66e-1)" "unprognostic (4.76e-2)" "unprognostic (5.30e-3)" "unprognostic (2.35e-1)" "unprognostic (9.07e-2)" "unprognostic (7.98e-2)" "unprognostic (2.03e-2)" "unprognostic (3.51e-2)" "unprognostic (1.97e-1)" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (2.09e-1)" "unprognostic (5.27e-2)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" 0.1 0.0 0.8 0.1 0.3 0.0 0.0 1.7 1.2 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.2 1.5 0.3 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.0 0.2 5.1 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 0.3 0.1 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 1.7 1.2 1.5 0.3 0.3 0.1 0.8 0.8 0.5 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.7 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.1 0.0 19.5 1.2 0.0 0.1 0.0 1.6 0.0 0.0 0.0 IL6 "BSF2, HGF, HSF, IFNB2, IL-6" ENSG00000136244 "Interleukin 6" P05231 7 22725884-22732002 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 217.6;urinary bladder: 281.3" "Group enriched" "Detected in many" 4 "Adipocytes: 188.5;Endometrial ciliated cells: 163.9;Endothelial cells: 287.4;Fibroblasts: 593.3;Glandular and luminal cells: 322.2;Smooth muscle cells: 449.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 44 "memory B-cell: 3.9;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 48 "B-cells: 4.8" "Group enriched" "Detected in many" 4 "BJ hTERT+: 2214.7;GAMG: 1447.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB023406, CAB072821" Supported Approved Vesicles "Secreted to blood" NA NA 5700 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB023406: AB_617317, CAB072821: " "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (3.59e-2)" "unprognostic (9.88e-3)" "unprognostic (1.35e-1)" "unprognostic (3.07e-3)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.10e-11)" "unprognostic (2.45e-3)" "unprognostic (2.10e-1)" "unprognostic (4.31e-2)" "unprognostic (7.80e-2)" 217.6 13.9 3.6 30.8 3.8 46.8 31.3 3.7 6.0 4.7 9.2 22.1 1.9 5.7 0.0 34.9 18.9 41.6 55.1 3.8 3.8 17.7 13.0 114.9 9.1 4.0 4.3 6.2 19.5 10.0 38.3 11.3 4.9 16.5 17.3 1.4 12.0 2.0 7.8 7.6 8.3 19.5 3.9 7.0 18.0 1.2 4.7 6.3 14.2 4.1 3.7 281.3 5.7 4.1 0.1 0.0 0.0 0.0 0.7 2.2 7.5 8.9 2214.7 43.2 151.0 0.0 0.6 0.2 71.6 15.2 1447.6 1.7 0.0 0.3 59.9 94.2 0.2 0.0 3.7 0.0 47.3 0.0 0.6 5.6 0.0 413.8 63.1 44.2 18.2 0.0 10.6 0.5 1.9 0.1 0.0 0.3 1.6 0.7 0.5 0.0 0.0 0.0 124.2 0.0 0.0 0.0 144.5 0.1 0.6 7.9 0.1 0.1 14.5 15.2 1.4 28.2 4.7 0.0 27.8 0.4 98.5 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 3.8 3.7 6.0 3.8 3.8 4.0 4.3 4.9 3.9 4.7 4.1 188.5 6.4 22.7 0.0 27.0 44.6 3.4 28.5 1.8 0.1 1.4 1.1 1.4 0.0 17.7 3.7 0.0 1.1 0.4 0.1 0.0 9.8 0.4 163.9 44.6 287.4 0.0 0.0 0.0 2.8 4.0 593.3 0.0 322.2 6.3 0.0 3.6 0.1 4.1 0.0 0.0 0.0 0.0 9.3 76.5 0.2 0.0 27.4 40.9 2.8 4.2 0.0 0.0 0.0 0.1 4.3 0.1 0.0 0.9 16.4 0.0 0.0 8.1 0.0 0.0 28.9 449.0 0.0 0.1 0.4 33.4 1.4 8.6 0.2 0.0 20.6 IL6R CD126 ENSG00000160712 "Interleukin 6 receptor" P08887 1 154405193-154469450 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.3;skeletal muscle: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.4;Hepatocytes: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 88.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 224.4;U-266/84: 274.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 24800000 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 41: Macrophages - Immune response" "unprognostic (1.19e-1)" "unprognostic (3.97e-1)" "unprognostic (1.19e-1)" "unprognostic (1.08e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-2)" "unprognostic (3.27e-1)" "unprognostic (6.42e-2)" "prognostic favorable (1.65e-4)" "unprognostic (7.94e-2)" "unprognostic (1.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" 11.0 5.8 6.8 25.5 8.0 16.6 5.9 7.4 11.3 7.6 4.8 14.7 15.6 8.4 2.5 7.4 12.4 9.0 6.6 6.2 6.4 14.2 58.3 16.3 27.3 10.9 8.8 8.9 8.7 1.2 8.9 6.6 9.8 6.0 9.8 1.4 3.3 2.9 94.2 6.4 19.8 8.8 10.4 19.8 10.2 3.4 10.6 9.3 2.7 26.4 22.4 9.3 5.3 10.4 3.3 5.8 0.4 0.4 3.4 5.1 0.4 3.3 2.5 2.0 1.0 0.6 3.9 0.2 7.4 4.1 12.0 1.7 1.1 17.8 1.6 62.6 1.9 0.8 2.2 13.9 0.5 9.6 5.0 3.0 10.5 1.7 26.1 0.6 2.6 0.1 0.7 24.0 0.6 1.4 0.2 16.0 1.8 1.1 13.5 0.3 0.3 53.6 10.9 4.5 0.5 0.3 1.1 36.2 59.5 4.5 3.3 224.4 2.5 3.5 3.4 3.3 2.2 43.1 274.1 0.4 4.4 61.0 5.7 7.5 29.4 28.1 0.6 18.0 1.5 1.5 15.2 1.6 36.1 0.6 14.9 5.4 88.2 1.3 8.0 13.1 21.2 15.8 6.8 8.0 7.4 11.3 6.2 6.4 10.9 8.8 9.8 10.4 10.6 10.4 3.4 115.4 82.7 18.6 11.0 37.9 72.9 8.3 13.1 0.1 7.5 7.4 9.9 25.8 33.9 1.8 0.0 0.5 16.9 38.5 0.0 4.3 35.1 34.1 5.7 10.9 7.7 3.8 5.7 1.2 1.2 26.3 25.5 48.7 61.3 1.3 3.9 108.6 42.9 0.0 5.9 6.5 14.2 41.8 79.3 14.5 0.3 63.7 24.9 44.0 76.8 3.8 4.1 3.0 3.3 7.5 8.7 0.4 41.9 58.9 60.1 15.5 29.0 0.2 0.0 28.3 19.2 0.4 1.1 7.2 29.7 1.0 17.1 0.1 15.4 17.0 IL6ST "CD130, GP130, sGP130" ENSG00000134352 "Interleukin 6 signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 580.3;Hepatic stellate cells: 808.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 16.7" "Lineage enriched" "Detected in many" 4 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 151.3;BJ hTERT+: 175.2;HHSteC: 155.1;HSkMC: 135.1;TIME: 147.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 160000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" 67.1 46.0 26.8 14.1 31.0 9.6 51.3 30.9 36.7 43.0 21.3 33.9 4.2 35.2 18.5 18.4 34.2 23.6 35.1 23.5 31.4 30.0 77.6 53.3 15.9 32.1 27.0 36.9 21.9 39.6 22.5 101.7 35.9 32.6 14.3 28.6 31.9 29.9 41.0 17.8 31.1 28.7 35.1 34.7 27.8 8.9 25.3 23.6 40.4 34.7 16.2 37.7 35.1 42.9 14.4 35.6 9.4 18.8 75.5 151.3 22.3 54.5 175.2 44.1 62.4 40.5 16.3 1.1 33.7 52.5 71.6 7.8 9.8 19.2 84.1 1.6 8.5 4.6 20.1 14.2 155.1 0.4 6.2 135.1 11.1 103.1 42.7 43.6 101.8 1.9 3.7 51.0 47.0 2.9 0.7 0.8 1.5 1.8 10.1 1.1 22.5 14.4 22.5 12.1 3.8 5.9 26.6 5.7 19.7 13.7 29.5 3.1 147.8 12.4 10.1 44.5 24.6 14.6 8.2 0.5 28.9 1.1 31.1 0.0 3.9 0.1 0.7 3.4 0.3 0.8 3.7 0.8 2.1 0.4 16.7 4.8 0.6 0.8 0.5 1.9 4.1 4.0 26.8 31.0 30.9 36.7 23.5 31.4 32.1 27.0 35.9 35.1 25.3 42.9 221.6 134.6 149.8 59.4 30.0 103.9 98.0 60.6 71.2 56.5 202.4 81.3 81.5 124.4 105.4 68.0 35.5 77.9 33.1 34.5 7.9 85.3 12.3 76.4 227.6 256.2 19.8 41.1 25.7 62.0 75.5 285.5 59.1 580.3 32.9 58.6 808.5 219.8 56.0 16.8 70.0 34.1 46.8 93.7 99.1 16.7 105.9 60.3 80.0 188.3 45.8 190.8 7.2 75.4 64.2 80.8 35.6 130.5 100.6 163.9 33.6 52.2 80.3 39.3 98.6 158.7 150.3 54.4 38.6 44.9 83.5 101.8 75.5 228.7 17.1 106.1 IL7 IL-7 ENSG00000104432 "Interleukin 7" P13232 8 78675743-78805523 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 108.8;Late spermatids: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.7;naive B-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;HDLM-2: 15.4;HEL: 18.2;HMC-1: 25.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019590 Approved "Secreted to blood" NA NA 60700 "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA019590: AB_10794621" "unprognostic (3.19e-3)" "unprognostic (1.44e-1)" "unprognostic (9.57e-3)" "unprognostic (5.45e-2)" "unprognostic (9.37e-3)" "unprognostic (3.36e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (6.55e-2)" "unprognostic (2.11e-4)" 2.3 1.2 0.2 4.1 0.3 2.1 1.5 0.4 0.2 2.3 0.3 5.1 6.7 1.1 0.3 3.5 4.8 3.1 0.6 0.3 0.5 1.4 4.2 3.3 8.7 0.6 0.4 0.9 1.0 0.0 0.5 0.3 0.5 1.8 4.4 0.7 1.1 0.9 0.1 8.8 8.7 1.1 0.4 3.5 3.8 1.7 1.2 0.8 1.3 0.1 4.2 2.8 1.5 0.2 0.3 0.0 0.1 0.0 0.4 0.4 0.0 1.4 1.4 1.3 1.9 0.0 7.6 0.1 0.0 4.4 4.5 4.2 0.1 0.0 0.0 15.4 0.0 18.2 0.6 2.1 0.1 0.1 25.4 1.3 0.0 0.2 0.6 4.9 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.1 0.0 5.4 3.2 0.0 2.4 2.6 0.3 0.2 0.0 0.1 0.0 0.2 0.8 0.9 0.0 2.0 0.3 0.0 0.0 3.4 0.0 1.9 5.2 0.3 0.0 0.4 0.2 0.0 9.7 1.0 1.0 2.2 8.7 0.2 0.3 0.0 0.5 0.8 0.3 7.3 0.6 0.2 0.3 0.4 0.2 0.3 0.5 0.6 0.4 0.5 0.4 1.2 0.2 0.6 0.0 3.6 5.9 12.2 6.0 3.2 1.2 10.8 0.1 1.3 0.9 0.7 5.7 2.4 1.8 0.0 0.0 1.3 7.8 9.8 1.2 108.8 22.9 0.8 4.9 3.0 10.5 16.0 5.1 0.0 2.5 11.2 0.6 0.0 0.1 1.8 2.4 0.9 0.0 11.0 6.2 2.0 1.0 3.3 145.5 0.6 1.9 0.0 1.0 3.4 2.0 0.0 20.1 6.0 2.6 11.5 1.2 1.0 1.2 12.4 9.5 24.2 0.4 0.0 2.2 0.5 2.3 0.9 5.2 6.5 0.0 1.6 0.1 4.6 1.7 IL9 "HP40, IL-9, P40" ENSG00000145839 "Interleukin 9" P15248 5 135892246-135895841 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 279 "HDLM-2: 43.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 11000 "Cluster 44: HDLM-2 - Immune response" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IMPG1 "GP147, IPM150, SPACR" ENSG00000112706 "Interphotoreceptor matrix proteoglycan 1" Q17R60 6 75921114-76072678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 267 "retina: 670.7" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 673.5;Rod photoreceptor cells: 694.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.2" "Region enriched" "Detected in single" 4 "basal ganglia: 3.3" "Not detected" "Not detected" "HPA027142, HPA030332, HPA030333" Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA027142: AB_2672132, HPA030332: AB_2673432, HPA030333: AB_2673433" "unprognostic (6.65e-2)" "unprognostic (4.13e-2)" "unprognostic (1.20e-1)" "unprognostic (8.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.49e-3)" "unprognostic (5.97e-2)" "unprognostic (3.56e-3)" "unprognostic (1.89e-2)" "unprognostic (2.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-3)" "unprognostic (2.84e-1)" "unprognostic (1.73e-2)" "unprognostic (2.09e-1)" "unprognostic (6.01e-2)" "unprognostic (1.96e-2)" 0.3 0.1 0.5 0.0 2.5 0.0 0.5 1.0 1.4 0.3 0.8 0.3 1.0 0.2 0.0 0.2 0.1 0.4 0.2 0.5 0.4 0.6 0.2 0.6 0.1 0.6 0.6 0.1 1.8 0.0 0.3 0.2 0.6 0.2 0.0 670.7 0.5 0.0 0.2 1.4 0.8 0.0 0.1 0.2 0.3 0.3 0.6 0.1 0.4 0.0 0.0 0.2 0.3 1.6 0.6 0.0 0.8 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 0.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 1.0 1.4 0.5 0.4 0.6 0.6 0.6 0.1 0.6 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 53.2 0.0 0.0 0.2 0.0 0.0 0.0 673.5 0.2 0.0 0.0 3.9 0.0 1.9 0.2 0.0 3.0 0.0 0.0 1.6 0.0 9.4 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 30.3 0.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 85.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 694.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 IMPG2 "IPM200, RP56, SPACRCAN" ENSG00000081148 "Interphotoreceptor matrix proteoglycan 2" Q9BZV3 3 101222546-101320575 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "retina: 305.4" "Group enriched" "Detected in some" 18 "Cone photoreceptor cells: 517.1;Rod photoreceptor cells: 329.1" "Cancer enriched" "Detected in single" 12 "ovarian cancer: 2.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008779, HPA015907" Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA008779: AB_2668138, HPA015907: AB_2669323" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (1.28e-1)" "unprognostic (4.80e-5)" "unprognostic (6.66e-4)" "unprognostic (1.85e-1)" "unprognostic (1.09e-1)" "unprognostic (6.59e-2)" "unprognostic (7.51e-3)" "unprognostic (1.28e-1)" "unprognostic (4.50e-9)" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (6.08e-2)" 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.3 0.1 1.7 0.1 0.0 0.1 0.1 0.0 9.6 0.1 0.1 0.2 1.1 0.3 0.0 0.0 0.2 0.9 0.3 0.1 0.1 0.0 0.1 0.0 1.1 0.1 0.1 305.4 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.3 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 1.1 0.9 0.3 1.1 0.2 0.3 0.2 0.3 0.0 0.0 5.9 0.4 0.1 0.0 0.1 0.0 22.8 0.1 0.5 0.6 0.0 0.1 0.0 517.1 0.0 0.3 0.0 1.9 0.1 0.3 0.7 0.5 2.4 0.0 0.0 7.5 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.0 0.1 0.1 13.5 14.0 0.0 0.0 0.3 0.0 0.0 0.6 0.3 0.0 4.7 1.2 23.4 0.0 8.5 2.6 0.1 0.0 0.7 0.6 0.1 0.0 0.0 0.5 329.1 0.0 0.6 0.3 0.1 0.3 0.0 0.3 0.0 0.2 1.2 0.0 0.0 INHA ENSG00000123999 "Inhibin subunit alpha" P05111 2 219569162-219575711 "Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 75.6;ovary: 104.4;testis: 95.3" "Cell type enhanced" "Detected in some" "Granulosa cells: 254.3;Syncytiotrophoblasts: 331.0;Theca cells: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.5;HEL: 4.5;SK-BR-3: 9.9;SuSa: 4.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB000047, HPA019141, HPA048834" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Golgi apparatus" "CAB000047: AB_322161, HPA019141: AB_1851789, HPA048834: " "unprognostic (8.90e-3)" "unprognostic (2.91e-2)" "unprognostic (2.82e-1)" "unprognostic (7.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.45e-1)" "unprognostic (3.57e-1)" "unprognostic (9.61e-3)" "unprognostic (4.15e-3)" "unprognostic (6.71e-2)" "unprognostic (3.73e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (4.03e-5)" "unprognostic (4.85e-2)" "unprognostic (7.20e-2)" "unprognostic (1.93e-1)" "unprognostic (4.43e-2)" 1.2 75.6 3.4 0.2 3.7 0.1 1.4 2.7 4.8 2.0 2.2 0.9 0.2 2.0 2.2 0.8 3.0 0.4 16.3 3.5 3.2 3.1 0.7 0.8 0.1 3.4 2.9 104.4 12.3 0.7 6.6 11.3 3.5 3.1 0.0 1.9 1.5 1.1 0.8 2.1 0.4 0.4 2.5 0.4 0.7 95.3 3.4 0.0 3.3 0.0 0.0 1.0 1.8 3.0 0.4 0.2 0.0 1.9 0.6 0.1 3.5 0.3 0.2 0.5 0.2 0.3 3.2 0.0 0.2 0.7 0.5 2.0 0.2 0.5 0.0 0.0 0.6 4.5 1.8 2.4 0.3 0.0 0.0 0.6 0.8 0.0 0.5 1.4 0.0 0.0 2.8 0.0 0.0 2.3 0.0 0.1 1.2 0.1 0.9 0.1 0.2 0.0 0.5 0.2 0.3 0.8 1.1 9.9 0.3 4.9 0.5 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.7 2.7 4.8 3.5 3.2 3.4 2.9 3.5 2.5 3.4 3.0 0.1 0.0 0.0 5.9 0.0 0.0 0.1 0.8 0.0 2.7 0.3 0.3 2.2 0.0 0.1 7.3 2.1 11.8 0.0 0.0 0.0 2.8 0.8 0.5 0.5 0.2 0.0 0.0 5.9 8.9 35.5 1.2 0.0 0.5 0.0 254.3 0.7 0.1 2.6 6.7 6.9 0.0 0.0 0.3 0.0 5.0 4.1 0.2 0.0 0.0 0.0 3.7 0.0 1.0 0.4 2.1 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 1.5 3.4 0.6 0.0 0.0 331.0 0.0 75.6 0.0 0.0 INHBA ENSG00000122641 "Inhibin subunit beta A" P08476 7 41667168-41705834 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 21.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 94.4;Langerhans cells: 68.0;Leydig cells: 137.6;Smooth muscle cells: 218.3;Syncytiotrophoblasts: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 75.9;hTEC/SVTERT24-B: 227.0;hTERT-HME1: 92.9;hTERT-RPE1: 139.2;TIME: 120.1;U-138 MG: 174.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 210000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (4.11e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (4.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.23e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (7.91e-8)" "unprognostic (6.22e-3)" "unprognostic (1.11e-2)" "unprognostic (3.25e-2)" "unprognostic (3.18e-3)" 2.3 1.5 2.1 5.1 2.0 10.4 0.9 2.3 7.8 1.5 0.7 1.0 0.8 17.3 3.7 2.1 1.2 21.6 5.4 8.7 3.3 2.8 9.5 11.0 1.2 4.3 8.1 6.8 0.6 0.5 0.5 10.9 3.4 3.2 0.6 2.3 5.4 5.0 0.5 2.0 0.5 4.3 4.5 0.5 0.8 1.7 3.0 0.2 1.2 4.6 0.4 10.3 1.1 3.4 4.2 0.0 0.4 0.1 3.3 7.1 0.0 18.2 1.9 9.9 3.3 0.0 0.4 0.0 1.1 6.9 11.6 15.3 0.0 75.9 9.6 5.1 0.0 0.0 0.0 0.0 13.9 0.0 0.2 7.0 4.2 227.0 92.9 139.2 8.2 0.0 0.5 0.0 23.0 0.2 0.0 0.3 1.5 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.1 5.7 11.1 0.6 0.0 6.2 0.1 0.2 120.1 174.7 49.7 18.9 19.0 0.0 0.0 0.0 6.7 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 2.1 2.0 2.3 7.8 8.7 3.3 4.3 8.1 3.4 4.5 3.0 3.4 0.7 3.2 15.7 0.0 0.9 17.3 10.8 13.5 2.2 0.1 3.5 6.5 6.0 0.0 4.4 0.0 0.0 1.4 0.3 0.1 0.0 23.6 0.6 1.4 4.1 5.9 0.0 0.0 2.4 2.0 4.6 42.0 0.0 2.6 7.6 94.4 0.7 18.5 1.5 0.0 0.2 0.2 4.1 1.4 68.0 5.9 137.6 55.8 14.2 0.0 27.0 16.1 0.0 4.0 0.3 11.1 0.1 23.3 0.0 12.5 0.0 0.1 2.8 1.3 0.0 4.9 218.3 0.7 0.3 1.4 8.9 178.4 1.7 18.8 0.2 2.3 INHBB ENSG00000163083 "Inhibin subunit beta B" P09529 2 120346136-120351803 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 52.5;breast: 43.3" "Group enriched" "Detected in many" 7 "Adipocytes: 200.5;Granulosa cells: 653.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 44.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 47.6;ASC diff: 63.1;BJ hTERT+ SV40 Large T+ RasG12V: 38.5;MCF7: 58.4;PC-3: 91.7;SK-BR-3: 163.4;T-47d: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 130000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.80e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.26e-2)" "unprognostic (4.26e-2)" "unprognostic (3.61e-3)" "unprognostic (2.13e-2)" "unprognostic (5.52e-2)" "unprognostic (6.99e-2)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.57e-3)" "unprognostic (4.14e-1)" "prognostic favorable (1.02e-4)" "unprognostic (1.76e-2)" 52.5 3.7 5.6 0.9 5.5 0.2 43.3 8.0 4.0 6.9 3.4 3.4 1.3 7.4 2.6 2.5 6.2 2.5 6.4 3.9 4.8 4.3 20.2 4.4 1.1 9.7 7.4 2.5 4.2 6.3 8.0 1.2 6.0 8.2 0.3 1.0 16.4 0.8 10.4 17.1 2.4 2.2 6.2 0.5 3.6 17.1 7.9 0.4 20.9 2.4 0.7 8.2 6.4 4.2 24.5 47.6 0.2 0.0 63.1 4.9 0.0 3.3 3.8 20.7 38.5 1.0 0.0 0.0 8.3 1.2 0.1 0.1 3.7 0.0 28.9 0.1 0.8 0.0 0.0 1.2 1.0 0.0 0.1 2.6 3.5 0.7 0.0 0.3 0.4 0.0 0.0 0.0 0.1 58.4 0.0 0.1 0.0 4.7 91.7 0.0 0.0 1.2 5.6 0.0 5.4 0.0 0.2 163.4 0.0 0.0 39.2 0.5 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.6 5.5 8.0 4.0 3.9 4.8 9.7 7.4 6.0 6.2 7.9 4.2 200.5 3.2 2.2 8.1 0.2 4.0 2.2 5.5 0.0 0.1 53.7 24.4 0.7 8.6 9.2 1.8 25.0 0.1 0.7 0.1 0.0 0.4 0.6 9.2 1.6 24.3 0.0 2.7 0.1 0.0 0.2 9.8 0.0 12.5 0.0 653.3 24.7 19.4 0.1 0.0 1.3 0.0 8.2 1.3 6.6 3.6 11.8 1.3 1.8 1.0 0.0 0.2 0.0 2.5 0.0 0.2 0.0 6.8 0.3 8.9 0.0 0.0 30.0 0.6 0.0 37.3 3.1 0.8 6.0 0.6 3.0 0.1 0.6 0.2 0.0 3.2 INHBC ENSG00000175189 "Inhibin subunit beta C" P55103 12 57434784-57452062 "Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 172 "liver: 165.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Hepatocytes: 5.7;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 6.4;Karpas-707: 6.3;RH-30: 2.8;U-266/70: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050755 Approved Cytosol "Secreted to blood" NA NA 21000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA050755: " "unprognostic (5.26e-2)" "unprognostic (4.58e-1)" "unprognostic (3.43e-3)" "unprognostic (4.08e-3)" "unprognostic (3.76e-1)" "unprognostic (1.98e-2)" "unprognostic (1.03e-2)" "unprognostic (1.10e-1)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-4)" "unprognostic (2.90e-2)" "unprognostic (1.52e-1)" "unprognostic (3.55e-3)" "unprognostic (5.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 165.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.2 0.0 6.4 0.0 0.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 1.6 0.0 6.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 2.8 0.5 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.7 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "liver: 148.4" "Cell type enriched" "Detected in single" 43 "Hepatocytes: 35.0" "Cancer enriched" "Detected in some" 27 "liver cancer: 34.4" "Region enhanced" "Detected in some" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 50.8;Karpas-707: 79.1;RH-30: 36.9;U-266/70: 263.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" NA NA 3500000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "CAB034017: AB_2233745, HPA016843: AB_1851796" "unprognostic (7.34e-2)" "unprognostic (6.73e-2)" "unprognostic (3.45e-1)" "unprognostic (4.69e-5)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.79e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.66e-8)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.52e-3)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.3 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 148.4 0.1 0.1 0.9 0.0 0.0 0.9 0.1 1.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.2 0.1 0.2 0.2 0.4 0.3 0.5 0.0 0.5 0.3 2.9 7.8 0.2 9.2 0.4 0.1 4.0 1.9 0.7 0.2 0.4 1.8 0.0 1.2 18.3 0.2 0.1 0.3 11.9 50.8 2.3 2.4 4.9 5.3 1.2 11.4 0.4 0.0 1.8 5.0 79.1 0.0 0.0 0.2 0.2 0.5 0.1 0.3 0.2 36.9 8.8 0.0 0.1 19.5 0.9 0.0 0.0 7.6 0.3 0.6 8.7 0.3 0.2 4.0 0.1 0.6 263.5 9.2 3.8 1.5 0.4 0.3 0.9 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.1 0.9 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 INS "IDDM1, IDDM2" ENSG00000254647 Insulin P01308 11 2159779-2161221 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism" Hormone "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "pancreas: 12983.6" "Cell type enriched" "Detected in some" 21 "Pancreatic endocrine cells: 1475.2" "Cancer enriched" "Detected in single" 7165 "pancreatic cancer: 1751.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "EFO-21: 268.3;U-2 OS: 376.2;U-698: 132.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 13 "midbrain: 1.3" "CAB000048, HPA004932, CAB012098, CAB053843" Enhanced "Secreted to blood" NA NA 437000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB000048: , CAB012098: AB_300968, CAB053843: AB_620123, HPA004932: AB_1851816" "unprognostic (7.61e-2)" 19.2 4.0 0.1 0.2 0.1 49.8 0.6 0.0 0.0 0.7 0.0 12.8 1.5 1.4 0.0 1.8 0.3 3.7 5.6 0.1 0.1 40.7 1.4 1.7 5.4 0.2 0.4 2.6 12983.6 0.0 0.3 1.4 0.8 0.5 0.0 0.0 3.1 0.0 0.3 96.4 0.7 0.0 0.0 1.4 42.2 0.3 0.0 0.0 1.3 0.0 0.0 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 268.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 376.2 0.0 31.8 0.0 15.9 132.4 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 67.2 0.0 0.0 0.0 0.0 1475.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INS-IGF2 ENSG00000129965 "INS-IGF2 readthrough" F8WCM5 11 2132538-2161209 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 48 "pancreas: 9.1" "Cell type enriched" "Detected in single" 11 "Hepatocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB019430 Enhanced "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 2: Hepatocytes - Metabolism" "CAB019430: AB_10691857" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INSL3 "MGC119818, MGC119819, RLF, RLNL" ENSG00000248099 "Insulin like 3" P51460 19 17816512-17821574 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 409.3" "Cell type enriched" "Detected in some" 19 "Theca cells: 24080.8" "Cancer enriched" "Detected in many" 21 "testis cancer: 39.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 5.7;PC-3: 2.6;SCLC-21H: 5.2;SH-SY5Y: 4.7" HPA028615 Enhanced "Secreted to blood" NA NA 566000 "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "HPA028615: AB_10600717" "unprognostic (3.25e-1)" "unprognostic (2.25e-4)" "unprognostic (3.50e-5)" "unprognostic (7.04e-2)" "unprognostic (1.74e-4)" "unprognostic (4.60e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (4.46e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-10)" "unprognostic (6.80e-3)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (1.09e-5)" 0.5 1.6 1.2 4.8 1.3 1.8 0.5 2.3 1.5 0.1 1.3 0.5 1.5 0.3 0.8 0.6 0.8 0.4 0.2 1.4 1.5 0.5 0.4 0.9 2.9 1.2 1.3 29.6 0.2 0.0 0.2 0.3 1.4 0.6 0.0 0.1 0.6 0.0 0.2 0.3 1.7 0.0 1.2 5.2 0.8 409.3 1.5 0.5 0.3 0.4 1.2 0.4 0.3 1.3 0.2 0.6 0.1 0.5 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.1 1.1 0.1 1.4 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.5 0.0 0.2 0.0 0.0 1.2 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 1.0 0.2 1.1 0.0 1.1 2.6 0.9 0.0 0.1 0.1 0.3 5.2 4.7 0.0 1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.4 2.1 0.1 0.1 1.3 0.0 0.4 0.2 0.0 0.7 0.4 0.7 0.0 0.9 0.9 0.1 1.1 0.7 1.0 2.2 0.5 0.1 0.1 0.8 0.5 1.2 1.3 2.3 1.5 1.4 1.5 1.2 1.3 1.4 1.2 1.5 1.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 2.3 0.0 0.0 0.1 6.8 0.0 0.1 3.4 0.0 0.0 0.3 0.0 0.4 42.3 0.0 0.0 0.0 0.9 0.4 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 257.1 1240.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 2.9 5.7 0.0 0.0 0.5 0.8 24080.8 0.0 0.0 INSL4 EPIL ENSG00000120211 "Insulin like 4" Q14641 9 5231419-5235304 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 15.9" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 3575.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "A549: 24.6" HPA065145 Approved Vesicles "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA065145: " "unprognostic (9.77e-2)" "unprognostic (2.02e-1)" "unprognostic (4.66e-1)" "unprognostic (7.74e-2)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 24.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 325.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 26.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3575.7 0.0 0.0 0.0 0.0 INSL5 ENSG00000172410 "Insulin like 5" Q9Y5Q6 1 66797741-66801256 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 106 "intestine: 128.9" "Cell type enriched" "Detected in some" 365 "Enteroendocrine cells: 8836.2" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;prostate cancer: 0.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA030100, CAB033849" Enhanced "Secreted to blood" NA NA 38500000 "Cluster 37: Intestine - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB033849: AB_2264904, HPA030100: AB_10601915" "unprognostic (2.48e-1)" "unprognostic (4.41e-2)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (2.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.62e-2)" "unprognostic (7.53e-2)" 0.0 0.0 0.9 0.0 0.9 0.0 0.1 0.8 1.1 0.0 1.2 75.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.8 0.5 0.0 0.0 0.0 1.1 1.0 0.0 0.0 0.0 0.2 0.0 0.9 0.1 128.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.4 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.8 1.1 0.8 0.8 1.1 1.0 0.9 0.9 0.8 0.9 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.2 0.3 0.0 0.0 8836.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 22.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 11.4 0.0 INSL6 RIF1 ENSG00000120210 "Insulin like 6" Q9Y581 9 5123880-5185647 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "retina: 6.8;testis: 14.9" "Cell type enhanced" "Detected in some" "Early spermatids: 134.0;Excitatory neurons: 22.0;Inhibitory neurons: 26.2;Late spermatids: 17.9;Microglial cells: 21.5;Spermatocytes: 35.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 1.1;Karpas-707: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021364 Enhanced "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA021364: AB_1851807" "unprognostic (3.85e-4)" "unprognostic (7.41e-4)" "unprognostic (1.28e-1)" "unprognostic (1.94e-1)" "unprognostic (2.22e-1)" "unprognostic (6.92e-2)" "unprognostic (2.31e-2)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (2.52e-3)" 0.1 0.3 0.5 0.6 0.7 1.5 0.0 1.1 1.2 0.0 0.1 0.2 0.3 0.4 0.0 0.4 0.1 0.5 0.5 0.4 0.9 0.1 0.1 0.2 1.0 0.6 0.2 0.4 0.0 0.0 0.0 0.8 0.6 0.2 0.0 6.8 0.2 0.0 0.3 1.0 0.2 0.0 0.1 1.1 0.6 14.9 0.5 0.1 0.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.1 0.3 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.3 1.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.7 1.1 1.2 0.4 0.9 0.6 0.2 0.6 0.1 0.5 1.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 134.0 0.1 0.0 0.1 0.0 0.0 22.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 26.2 0.0 0.0 0.0 0.0 17.9 1.2 0.0 0.0 21.5 0.0 0.0 0.0 9.5 8.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 35.7 10.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 ISG15 "G1P2, IFI15, UCRP" ENSG00000187608 "ISG15 ubiquitin like modifier" P05161 1 1001138-1014540 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 320.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 497.1;Paneth cells: 403.1;Proximal enterocytes: 461.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 1460.2;BJ hTERT+ SV40 Large T+ RasG12V: 1466.7;HeLa: 501.4;SK-MEL-30: 487.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004627 Approved "Secreted to blood" NA NA 5000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA004627: AB_1079152" "unprognostic (3.65e-1)" "unprognostic (1.06e-1)" "unprognostic (1.12e-2)" "unprognostic (4.62e-2)" "unprognostic (3.96e-3)" "unprognostic (1.38e-1)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (3.78e-3)" "unprognostic (2.07e-3)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.11e-10)" "unprognostic (4.55e-2)" "unprognostic (4.13e-2)" "unprognostic (1.12e-2)" "unprognostic (7.46e-2)" 46.8 24.3 42.9 36.9 39.8 136.1 39.0 42.0 49.9 79.0 32.6 47.0 42.5 29.6 3.9 24.0 19.9 31.3 55.4 38.3 36.8 73.2 113.5 59.9 29.7 63.2 42.7 17.6 18.9 8.8 40.3 44.8 63.8 28.1 6.9 1.1 320.4 14.1 15.9 13.4 34.8 18.2 134.8 75.3 31.3 10.5 48.7 48.5 34.7 8.1 11.6 29.2 25.7 38.3 58.1 8.5 4.4 38.2 6.0 11.8 33.2 39.5 95.7 1460.2 1466.7 95.6 91.7 51.4 282.0 33.4 248.2 36.1 4.5 17.3 22.7 58.2 23.7 24.3 501.4 65.2 53.8 15.4 94.5 24.6 5.6 92.7 1.8 4.8 46.1 67.7 14.1 27.4 12.0 282.3 50.0 253.5 4.7 36.3 315.3 85.7 11.0 26.1 19.2 18.0 2.0 1.8 77.1 12.6 487.0 1.9 2.9 29.8 25.8 28.5 27.4 13.2 8.7 35.5 19.6 39.6 27.9 60.2 2.7 508.7 278.6 871.3 228.3 425.4 295.5 259.1 258.6 251.7 174.8 215.7 165.2 191.1 663.3 276.7 381.1 59.4 509.7 217.6 42.9 39.8 42.0 49.9 38.3 36.8 63.2 42.7 63.8 134.8 48.7 38.3 240.1 38.5 17.5 1.6 71.8 44.6 47.9 83.7 9.1 2.0 29.3 21.5 24.3 25.8 61.8 46.0 0.0 24.2 213.7 289.1 5.9 134.1 3.5 65.5 66.1 200.5 35.2 8.0 0.6 280.4 497.1 84.5 25.0 95.4 60.9 113.8 70.6 58.2 273.6 0.0 2.2 104.9 63.1 62.0 273.8 14.0 32.9 170.4 88.9 13.1 132.5 21.2 134.9 2.5 0.3 192.0 403.1 41.3 48.7 39.3 461.3 32.1 50.7 3.2 98.6 15.4 179.1 6.2 7.3 7.9 36.9 32.3 169.4 63.0 39.5 55.4 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ISM1 "bA149I18.1, C20orf82" ENSG00000101230 "Isthmin 1" B1AKI9 20 13221274-13300651 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 44.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 19.2;Fibroblasts: 18.4;Microglial cells: 8.4;Proximal tubular cells: 5.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 48.9;Hep G2: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 17000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (7.13e-2)" "unprognostic (3.55e-1)" "unprognostic (4.43e-3)" "unprognostic (5.27e-3)" "unprognostic (1.84e-2)" "unprognostic (5.56e-2)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.06e-1)" "unprognostic (4.48e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.32e-6)" "unprognostic (2.58e-2)" "unprognostic (2.10e-1)" "unprognostic (6.83e-2)" "unprognostic (1.81e-2)" 13.2 2.6 1.2 0.3 1.2 0.0 16.6 0.9 1.5 3.3 0.5 2.0 0.4 3.1 0.3 6.6 4.4 4.8 2.9 1.1 3.5 2.1 6.3 4.4 0.3 1.4 1.6 0.5 3.8 0.4 2.1 14.4 1.5 1.6 0.2 0.1 15.2 0.7 1.5 17.0 2.6 1.9 1.3 8.1 3.3 0.1 3.6 4.9 44.4 2.0 0.7 1.3 5.6 0.8 0.0 0.5 0.2 0.7 48.9 6.8 0.3 0.4 4.2 0.0 0.0 2.9 0.4 0.0 0.2 0.0 0.4 0.2 0.0 0.1 0.0 0.0 4.1 0.0 0.0 20.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.4 0.0 0.5 0.5 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.1 4.2 0.0 0.0 1.4 0.2 0.9 0.0 0.0 0.0 2.9 0.4 0.1 0.3 0.0 4.7 0.9 0.0 2.3 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.2 1.2 0.9 1.5 1.1 3.5 1.4 1.6 1.5 1.3 3.6 0.8 1.9 0.0 0.5 0.0 0.0 4.6 0.4 0.4 0.6 0.8 0.5 19.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.1 0.2 2.0 2.0 0.0 0.0 0.6 0.0 0.3 18.4 0.0 0.2 0.0 3.4 0.0 2.3 0.5 0.0 4.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 1.8 8.4 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.4 0.1 0.5 0.0 5.2 0.0 0.0 0.0 0.4 1.4 0.0 0.3 0.3 2.8 0.7 0.9 0.0 0.0 0.1 ISM2 "FLJ32147, TAIL1, THSD3" ENSG00000100593 "Isthmin 2" Q6H9L7 14 77474394-77498816 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "placenta: 213.4" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 291.0;Extravillous trophoblasts: 617.2;Syncytiotrophoblasts: 177.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "BEWO: 386.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039314, HPA039742" Supported Supported Nucleoplasm "Secreted in female reproductive system" NA NA 1100000 "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA039314: AB_10673239, HPA039742: AB_10673427" "unprognostic (5.69e-2)" "unprognostic (9.17e-3)" "unprognostic (2.58e-2)" "unprognostic (1.41e-3)" "unprognostic (3.73e-2)" "unprognostic (2.34e-1)" "unprognostic (2.16e-2)" "unprognostic (3.09e-3)" "unprognostic (2.11e-1)" "unprognostic (4.13e-1)" "unprognostic (8.10e-2)" "unprognostic (1.42e-2)" "unprognostic (9.36e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (3.95e-1)" 0.6 0.0 0.3 0.1 1.2 0.0 0.0 0.0 0.7 0.8 0.8 0.2 0.1 1.2 3.7 0.2 0.4 0.1 0.1 0.2 0.6 0.7 0.0 0.0 0.0 0.1 0.3 0.1 0.6 0.4 0.5 213.4 0.2 1.8 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.6 0.8 0.0 0.2 0.0 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 386.3 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.3 0.5 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.7 0.2 0.6 0.1 0.3 0.2 0.1 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 291.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.0 617.2 2.1 0.0 0.0 0.0 0.1 0.0 0.0 33.4 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 1.7 0.0 0.0 177.5 0.0 0.0 0.0 0.0 ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 76.1;Skeletal myocytes: 93.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 208.3;ASC TERT1: 138.7;fHDF/TERT166: 345.3;LHCN-M2: 311.8" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 56.9" "Secreted - unknown location" NA NA 37000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.12e-4)" "unprognostic (1.45e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.84e-2)" "unprognostic (2.16e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-5)" "unprognostic (1.44e-2)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.70e-4)" 16.9 9.2 1.8 0.7 1.8 0.1 18.0 2.6 2.3 23.8 2.5 1.5 0.5 2.0 0.5 9.7 4.9 38.3 18.3 1.9 3.6 2.7 7.7 25.4 1.3 3.9 2.3 5.3 7.9 5.6 10.3 33.4 4.3 4.0 2.5 0.1 11.7 4.4 4.5 13.2 0.5 4.1 3.5 4.0 7.2 2.5 2.2 0.9 8.4 14.9 4.3 17.8 10.0 6.5 4.2 0.3 0.0 0.0 208.3 138.7 0.0 65.8 67.7 29.3 18.7 0.0 2.4 0.0 0.3 345.3 13.9 70.9 0.0 24.1 46.0 0.0 0.0 21.3 0.6 0.0 21.7 0.0 0.0 59.3 1.5 16.8 46.6 55.3 76.8 0.0 1.5 0.7 311.8 0.0 0.0 0.0 0.0 0.0 24.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 8.8 24.0 33.2 27.3 0.1 8.3 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 2.6 2.3 1.9 3.6 3.9 2.3 4.3 3.5 2.2 6.5 1.9 3.2 0.5 5.5 0.1 4.0 0.1 1.3 0.6 1.8 4.2 19.0 0.5 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.5 4.5 0.5 7.7 1.2 0.0 0.0 3.6 0.2 0.8 76.1 5.6 1.1 0.0 0.0 8.6 0.5 0.7 5.0 6.7 0.0 0.0 0.0 4.7 2.1 0.0 0.8 5.4 13.1 0.0 0.5 0.0 2.0 5.0 1.1 0.0 8.2 0.6 0.2 0.0 0.1 0.0 0.7 0.0 93.0 4.8 11.6 8.4 0.7 2.4 0.8 0.4 1.2 0.0 0.2 ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 782 "liver: 1504.9" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1087.0" "Cancer enriched" "Detected in some" 598 "liver cancer: 329.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.3;Hep G2: 1.7;HL-60: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" NA NA 4490000 59000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA041639: AB_10796349, HPA042049: AB_10797379" "unprognostic (1.87e-4)" "unprognostic (1.31e-3)" "unprognostic (2.38e-1)" "unprognostic (8.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-3)" "prognostic favorable (1.89e-5)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-4)" "unprognostic (4.02e-3)" "unprognostic (5.70e-3)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" 0.8 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.2 1504.9 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 1.9 0.4 0.4 0.0 0.4 0.0 0.1 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.1 0.0 29.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 18.5 1087.0 0.1 0.0 0.0 0.0 0.0 20.2 0.0 1.7 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.1 ITIH2 H2P ENSG00000151655 "Inter-alpha-trypsin inhibitor heavy chain 2" P19823 10 7703316-7749520 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 668 "liver: 2156.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 489.6" "Cancer enriched" "Detected in many" 279 "liver cancer: 626.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 453 "Hep G2: 1103.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059150 Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 32000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "HPA059150: AB_2683930" "unprognostic (4.82e-2)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.21e-2)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" "prognostic favorable (1.48e-4)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (2.28e-1)" "unprognostic (2.02e-1)" "unprognostic (2.10e-8)" "unprognostic (9.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.35e-1)" "unprognostic (4.46e-4)" 0.1 0.2 0.3 0.1 1.1 0.1 3.0 1.6 3.2 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.1 0.6 1.0 0.8 2156.1 0.6 0.1 0.6 0.5 0.0 0.2 0.0 1.7 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.4 0.0 0.0 0.9 0.3 0.5 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 1103.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.1 0.7 0.0 0.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.1 1.6 3.2 0.6 1.0 0.6 0.5 0.6 0.9 0.9 0.7 0.1 0.0 2.2 0.7 1.0 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.4 117.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.1 0.0 0.0 0.6 0.0 2.7 3.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 8.2 489.6 0.1 0.0 1.4 0.0 0.0 9.4 0.0 2.1 0.0 0.0 0.0 18.7 0.0 0.0 0.0 1.5 1.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 ITIH3 H3P ENSG00000162267 "Inter-alpha-trypsin inhibitor heavy chain 3" Q06033 3 52794768-52809009 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 97 "liver: 792.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1183.8" "Cancer enriched" "Detected in some" 247 "liver cancer: 273.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 17.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA017373 Approved "Secreted to blood" NA NA 9100000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017373: AB_1851954" "unprognostic (2.07e-2)" "unprognostic (5.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.30e-4)" "unprognostic (4.28e-2)" "unprognostic (3.26e-2)" "unprognostic (5.97e-2)" "unprognostic (6.07e-2)" "unprognostic (1.49e-1)" "unprognostic (7.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.49e-8)" "unprognostic (2.09e-4)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (9.31e-2)" 5.0 0.7 0.5 0.9 0.7 0.0 2.1 0.5 0.8 5.3 0.4 1.1 0.3 3.5 1.7 1.3 3.4 1.2 0.7 0.5 0.4 0.7 792.7 3.0 2.5 0.4 0.4 2.8 0.3 0.1 0.3 1.7 0.5 1.1 1.0 0.1 0.4 2.4 0.6 1.3 1.2 1.2 0.4 8.1 1.2 3.5 0.4 0.2 1.2 0.4 1.7 1.4 2.3 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.5 0.8 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.1 0.0 0.0 0.0 21.6 0.1 0.0 0.0 0.0 0.5 0.1 1.4 0.8 78.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.1 0.1 3.5 0.0 90.9 0.0 0.0 0.1 2.1 0.0 0.0 0.0 12.3 66.4 1183.8 0.0 0.0 0.0 0.0 0.0 85.1 0.3 132.0 1.2 0.1 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 9.1 0.4 0.3 0.0 0.1 0.3 3.6 19.2 0.0 0.1 ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "liver: 1863.4" "Group enriched" "Detected in many" 5 "Early spermatids: 119.2;Hepatocytes: 134.6;Late spermatids: 126.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.4;JURKAT: 2.0;U-266/70: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" NA NA 3060000 58000000000 "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB072872: AB_2665724, HPA001835: AB_1079432, HPA003948: AB_1079433" "unprognostic (6.08e-2)" "unprognostic (4.45e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.96e-1)" "unprognostic (5.86e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-14)" "unprognostic (1.71e-3)" "unprognostic (2.96e-2)" "unprognostic (1.52e-1)" "unprognostic (4.21e-5)" 4.2 18.5 4.1 1.2 4.2 10.0 3.0 3.7 5.0 4.2 3.5 3.6 1.0 2.9 1.7 1.4 3.8 1.1 3.2 3.9 3.6 5.4 1863.4 4.9 1.7 3.9 3.8 2.4 48.9 0.1 4.3 0.7 3.9 4.0 1.0 3.3 2.1 1.8 40.3 2.5 3.4 1.5 3.6 7.4 3.9 1.8 3.8 2.2 5.2 2.8 1.2 5.3 3.3 3.9 0.0 0.1 0.4 0.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.2 0.1 0.4 0.0 0.0 0.2 2.4 0.1 1.0 0.0 1.2 0.4 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 0.3 0.8 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.8 0.3 0.0 0.2 0.3 0.0 0.4 0.3 0.0 0.1 0.4 0.5 0.3 0.1 0.0 0.4 0.4 0.0 3.0 1.4 0.2 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 4.1 4.2 3.7 5.0 3.9 3.6 3.9 3.8 3.9 3.6 3.8 3.9 0.7 0.0 1.1 22.5 0.9 0.8 0.3 0.3 0.0 10.0 0.6 1.3 1.1 2.8 0.8 0.0 12.5 0.0 0.4 0.1 0.0 0.3 119.2 0.7 0.7 0.8 0.0 8.4 11.6 2.6 0.0 0.6 1.1 0.4 0.0 2.7 2.5 134.6 0.5 5.0 8.6 0.2 0.0 2.2 1.0 126.5 1.2 1.3 0.0 5.6 1.9 2.3 2.1 3.0 3.1 2.3 0.5 1.9 0.7 0.2 0.0 0.3 0.3 6.0 6.6 6.2 2.4 1.3 1.5 0.0 0.3 0.3 1.2 3.2 0.1 0.1 ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 282.7;Fibroblasts: 111.3;Microglial cells: 160.2;Smooth muscle cells: 110.1;Syncytiotrophoblasts: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" 112.7 3.7 17.9 19.4 18.6 0.2 53.3 19.7 23.2 17.4 28.6 62.7 13.9 24.3 6.3 21.4 10.5 27.7 16.8 14.7 18.0 16.4 1.6 22.4 12.5 18.9 18.1 21.2 15.0 6.3 5.4 86.9 19.7 24.0 16.8 3.5 9.5 46.6 17.8 12.0 21.6 28.8 15.7 3.4 24.0 6.2 22.5 3.8 24.5 22.5 13.4 51.4 15.3 15.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 18.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 14.8 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.1 0.0 0.0 0.0 102.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.6 19.7 23.2 14.7 18.0 18.9 18.1 19.7 15.7 22.5 15.2 74.9 3.2 2.7 1.3 0.2 11.3 3.0 0.1 6.8 2.7 1.6 17.3 8.7 8.6 3.7 0.0 2.1 282.7 0.8 0.1 0.0 25.7 2.0 18.7 1.5 58.8 0.0 0.0 0.5 0.4 70.2 111.3 0.0 34.1 2.5 0.5 1.8 0.1 20.7 0.0 0.7 0.0 8.2 1.2 19.6 2.2 5.3 3.6 14.2 160.2 1.1 21.9 0.0 1.5 1.0 0.3 0.0 15.4 0.9 1.8 0.2 2.1 0.7 3.2 78.9 32.3 110.1 1.7 7.7 0.7 8.8 221.9 3.0 0.3 0.0 1.6 ITIH6 "ITIH5L, UNQ6369" ENSG00000102313 "Inter-alpha-trypsin inhibitor heavy chain family member 6" Q6UXX5 X 54748918-54798255 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "melanoma: 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "WM-115: 50.7" HPA000506 Uncertain "Secreted to blood" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 35: Glandular cells - Unknown function" "HPA000506: AB_2666007" "unprognostic (3.40e-1)" "unprognostic (1.04e-1)" "unprognostic (9.73e-3)" "unprognostic (7.24e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-3)" "unprognostic (9.81e-2)" "unprognostic (2.66e-1)" "unprognostic (1.02e-1)" "unprognostic (6.33e-2)" "unprognostic (4.14e-4)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (2.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 50.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ITLN1 "FLJ20022, hIntL, HL-1, ITLN, LFR" ENSG00000179914 "Intelectin 1" Q8WWA0 1 160876540-160885180 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 757.3;intestine: 1247.8" "Cell type enriched" "Detected in many" 14 "Intestinal goblet cells: 1818.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 61.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "intermediate monocyte: 9.2;non-classical monocyte: 24.1" "Lineage enriched" "Detected in many" 17 "monocytes: 24.1" "Group enriched" "Detected in some" 4 "HEL: 2.6;HL-60: 1.9;OE19: 7.2;U-937: 7.1" "Not detected" "Not detected" "CAB012652, HPA063275, HPA067326" Enhanced "Secreted to blood" NA NA 294000000 6400000 "Cluster 51: Monocytes - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB012652: , HPA063275: AB_2684974, HPA067326: AB_2732764" "unprognostic (9.69e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-3)" "unprognostic (2.28e-1)" "unprognostic (1.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (5.22e-3)" "unprognostic (1.66e-2)" "unprognostic (4.38e-1)" "unprognostic (9.96e-2)" "unprognostic (3.67e-1)" "unprognostic (8.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-2)" 757.3 0.3 0.0 26.4 0.0 2.6 0.5 0.0 0.0 0.3 0.0 444.2 272.7 0.5 2.1 0.4 6.2 0.8 233.8 0.0 0.0 35.5 3.1 40.3 0.3 0.0 0.0 9.7 3.3 0.0 0.4 1.3 0.0 0.6 1247.8 0.0 24.9 3.3 0.7 0.2 415.7 7.7 0.0 2.5 15.9 2.0 0.0 0.7 0.6 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 1.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.2 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 7.1 0.0 0.0 0.5 0.0 0.0 9.2 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.2 0.0 24.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 4.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.6 71.4 2.1 3.7 0.0 0.1 0.1 46.4 0.0 37.7 0.8 0.0 0.0 4.3 18.0 4.0 0.0 3.6 1.4 87.8 8.6 0.0 1.3 1.4 60.7 1.9 0.8 0.0 0.0 1818.6 0.0 124.7 0.0 0.7 14.6 1.8 0.0 0.0 0.3 0.0 1.0 0.0 0.0 7.3 17.7 3.0 0.0 0.3 15.4 0.1 0.8 0.0 0.0 0.0 10.8 0.1 0.9 0.0 0.0 0.3 2.1 15.3 59.4 0.1 ITLN2 HL-2 ENSG00000158764 "Intelectin 2" Q8WWU7 1 160945025-160954809 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "intestine: 408.3" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 1: 76.9" "Group enriched" "Detected in many" 4 "colorectal cancer: 2.8;testis cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 11.9;HHSteC: 1.9;HMC-1: 3.4;SK-MEL-30: 4.0;SuSa: 3.8" "Low region specificity" "Detected in all" "HPA006683, HPA067326" Enhanced "Secreted to digestive system" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 11: Alveolar cells - Smell perception" "HPA006683: AB_2129681, HPA067326: AB_2732764" "unprognostic (1.42e-1)" "unprognostic (9.62e-3)" "unprognostic (4.61e-2)" "unprognostic (7.45e-2)" "unprognostic (2.25e-1)" "unprognostic (6.84e-4)" "unprognostic (2.47e-2)" "unprognostic (5.74e-2)" "unprognostic (1.31e-2)" "unprognostic (1.36e-1)" "unprognostic (5.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.49e-1)" "unprognostic (2.31e-1)" "unprognostic (4.91e-2)" 6.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 238.7 0.1 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.4 11.7 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.0 0.2 408.3 0.0 0.0 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 1.9 0.0 3.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 4.0 3.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.9 5.3 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 0.3 1.4 0.0 0.2 0.0 0.4 11.0 0.3 0.1 0.0 0.0 5.0 0.0 0.3 0.0 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 5.3 0.0 0.6 14.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 6.3 17.5 0.4 ITM2B "BRI, BRI2, BRICD2B, E25B, E3-16" ENSG00000136156 "Integral membrane protein 2B" Q9Y287 13 48232612-48270357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Amyloidosis, Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4375.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 4375.2" "Cell line enhanced" "Detected in all" "HMC-1: 731.2;RPTEC TERT1: 1718.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029292, HPA071992" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 5800000 "Cluster 5: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus, Vesicles" "HPA029292: AB_10601917, HPA071992: AB_2686480" "unprognostic (4.66e-2)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.00e-1)" "unprognostic (4.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "unprognostic (9.88e-2)" "unprognostic (2.42e-1)" "unprognostic (5.89e-2)" "unprognostic (2.87e-2)" "prognostic favorable (3.73e-5)" "unprognostic (4.38e-2)" "unprognostic (4.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" 510.2 367.4 286.9 172.5 301.0 125.6 323.8 328.6 489.0 416.1 406.6 260.1 289.2 388.8 1171.8 399.9 305.4 257.5 381.0 320.1 339.2 1306.3 391.2 376.1 236.7 334.9 308.0 507.2 179.6 233.7 290.5 573.8 304.4 312.5 191.4 174.4 408.7 386.2 164.7 399.6 287.4 232.5 373.6 435.2 312.8 121.4 308.8 188.3 386.1 206.2 187.4 305.1 402.2 394.8 67.6 51.8 73.1 116.3 348.5 254.5 119.2 215.0 202.2 87.5 100.6 29.1 248.3 16.6 168.8 121.6 48.5 214.1 61.3 107.0 107.4 69.9 147.3 137.9 29.0 99.0 138.5 140.6 731.2 113.4 149.1 45.1 62.0 375.7 131.2 78.3 24.5 90.9 174.8 29.6 200.4 310.1 266.0 116.5 103.6 100.1 100.5 73.6 1718.9 268.6 26.2 119.5 154.5 110.2 111.0 306.0 74.0 119.4 180.5 62.9 73.8 95.7 85.4 72.9 59.6 2.5 78.0 75.3 155.3 3091.4 864.5 2737.9 387.4 661.3 512.5 235.3 523.1 476.4 428.9 245.3 551.3 466.8 4375.2 356.5 692.7 196.2 563.4 1723.5 286.9 301.0 328.6 489.0 320.1 339.2 334.9 308.0 304.4 373.6 308.8 394.8 1380.0 695.5 300.4 174.6 408.6 862.4 1661.1 2606.2 1006.2 653.1 460.1 573.5 384.8 722.0 1121.9 1991.8 187.7 1164.3 448.2 754.2 545.9 910.2 23.6 751.8 802.2 1166.2 283.3 307.0 114.2 682.9 2362.8 1334.0 302.8 1177.2 578.0 421.2 1319.7 557.3 2117.8 353.3 142.6 503.2 1129.1 1569.8 900.6 76.7 1867.0 1381.5 681.3 252.0 1415.7 1634.9 425.3 174.4 237.9 515.7 788.3 2011.6 445.4 922.5 1259.3 2748.9 795.6 219.4 1222.7 602.4 1022.9 143.6 256.4 1384.6 1149.6 1471.5 723.2 665.5 440.9 1613.4 IZUMO4 C19orf36 ENSG00000099840 "IZUMO family member 4" Q1ZYL8 19 2096429-2099593 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 443.1" "Group enriched" "Detected in many" 51 "Early spermatids: 1750.8;Late spermatids: 2537.9;Spermatocytes: 824.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Karpas-707: 8.5;RPMI-8226: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048496 Enhanced "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA048496: AB_2680419" "unprognostic (2.75e-3)" "unprognostic (1.10e-2)" "unprognostic (3.65e-2)" "prognostic favorable (7.08e-4)" "unprognostic (1.40e-1)" "unprognostic (2.18e-5)" "unprognostic (2.67e-2)" "unprognostic (1.02e-3)" "unprognostic (1.30e-1)" "unprognostic (2.48e-1)" "prognostic favorable (1.69e-4)" "unprognostic (2.12e-1)" "unprognostic (6.58e-5)" "unprognostic (6.38e-2)" "unprognostic (2.17e-1)" "unprognostic (5.68e-1)" "unprognostic (7.51e-3)" 2.9 1.9 15.2 1.2 15.3 0.5 3.3 15.1 20.9 2.7 15.1 3.0 0.5 2.6 2.5 2.6 5.1 1.9 3.0 14.6 14.4 4.3 5.4 2.1 1.8 15.1 15.7 6.5 8.6 0.8 10.1 0.4 15.2 7.5 0.8 2.9 2.4 2.4 2.6 2.5 2.0 0.7 14.9 1.6 3.9 443.1 15.6 1.7 4.6 1.2 2.2 2.5 2.3 15.7 0.6 0.5 0.3 2.7 1.1 1.2 0.3 0.4 0.6 0.4 0.0 0.2 0.5 0.4 0.6 0.6 0.0 0.5 0.0 2.9 0.1 1.2 0.2 0.0 1.1 0.8 3.2 0.0 0.4 0.5 1.1 0.7 0.8 0.9 0.0 1.5 0.0 8.5 1.1 0.1 0.8 0.2 0.3 1.1 0.7 0.7 0.0 10.9 1.2 0.3 0.4 0.7 0.4 0.9 0.4 0.2 0.5 1.0 0.0 0.3 0.1 0.1 0.2 0.9 1.1 0.8 1.4 0.9 0.2 0.0 0.7 0.6 0.6 1.1 1.5 2.7 2.1 1.6 0.9 0.7 1.7 0.7 1.6 0.5 1.6 1.2 2.2 0.9 15.2 15.3 15.1 20.9 14.6 14.4 15.1 15.7 15.2 14.9 15.6 15.7 1.0 0.0 0.0 31.0 10.3 2.4 4.1 32.8 4.0 3.4 2.5 2.3 1.5 5.7 19.7 9.2 8.4 0.5 2.6 2.0 5.9 2.5 1750.8 4.6 1.9 1.7 7.7 0.4 1.2 5.8 4.5 3.7 1.1 2.3 0.0 2.2 0.7 9.5 1.0 0.0 1.6 1.9 14.2 3.2 8.2 2537.9 28.6 4.3 12.4 0.0 11.3 6.6 1.0 1.5 28.0 1.8 0.7 19.9 8.2 6.8 1.9 11.1 12.1 8.6 6.6 2.6 2.1 824.6 14.3 6.3 1.7 1.6 5.6 2.4 4.4 7.0 JAM3 "JAM-C, JAMC" ENSG00000166086 "Junctional adhesion molecule 3" Q9BX67 11 134069071-134152001 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 342.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.3" "Group enriched" "Detected in many" 7 "B-cells: 5.3;T-cells: 2.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;RH-30: 122.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003417, HPA050434" Approved Enhanced "Golgi apparatus" "Secreted to blood" NA NA 44000 "Cluster 43: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "HPA003417: AB_1851981, HPA050434: AB_2681126" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (3.24e-1)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.59e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (5.06e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.23e-3)" "unprognostic (2.17e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.68e-4)" 23.6 18.7 53.4 10.1 86.3 1.3 19.2 68.7 73.4 33.4 52.9 54.6 6.6 40.8 17.5 21.5 28.7 24.5 31.0 56.5 61.3 11.4 3.2 29.6 7.8 73.5 76.8 48.7 5.1 17.7 33.3 102.7 71.0 32.5 12.9 47.3 13.3 44.5 7.0 13.0 22.5 42.8 59.7 13.5 22.4 35.7 73.3 17.6 15.8 14.6 7.5 41.7 23.4 115.2 0.0 1.0 87.9 42.5 85.3 62.7 75.4 37.0 49.1 15.1 14.8 0.3 0.6 0.0 38.7 53.3 56.2 0.5 70.0 0.7 28.2 0.2 29.6 0.3 0.0 6.9 24.9 0.4 36.2 43.2 0.0 10.7 9.6 35.8 99.5 40.8 0.3 0.2 64.5 1.0 27.5 0.2 18.9 0.6 2.9 0.5 122.8 0.0 0.9 0.2 57.5 32.2 0.0 0.2 1.0 35.3 0.2 0.2 0.6 25.1 18.4 40.3 24.7 0.1 0.1 0.4 27.6 1.2 48.0 0.0 0.0 0.1 1.3 0.0 1.6 5.3 1.6 0.9 0.0 3.1 2.3 1.7 0.5 0.0 0.0 0.0 0.0 1.8 53.4 86.3 68.7 73.4 56.5 61.3 73.5 76.8 71.0 59.7 73.3 115.2 22.2 0.0 6.0 12.7 10.9 5.1 5.6 0.9 0.0 21.7 0.3 9.3 15.7 0.0 0.7 5.5 8.4 6.0 1.2 0.1 1.9 0.4 2.1 0.8 23.3 35.5 0.0 0.4 84.3 0.2 71.2 29.6 1.5 0.5 1.3 11.7 12.5 0.0 8.6 8.4 44.2 0.0 12.2 0.6 4.2 4.9 42.9 10.9 17.8 24.4 0.2 20.2 1.0 76.4 342.8 0.3 0.0 64.3 0.9 2.2 0.0 0.2 1.5 75.6 26.3 19.0 24.3 15.5 19.2 0.2 3.8 6.2 3.5 9.7 0.0 1.0 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 23.0;Gastric mucus-secreting cells: 44.4;Intestinal goblet cells: 53.5;Proximal enterocytes: 78.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 30.8;T-47d: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011800 Uncertain "Secreted to extracellular matrix" NA NA 65000 "Cluster 64: Macrophages - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" 2.9 0.6 0.3 0.6 0.2 0.3 2.8 0.3 0.4 7.1 0.1 1.9 2.8 2.0 1.3 0.6 2.1 0.6 8.1 0.5 0.2 2.0 0.5 1.2 0.7 0.4 0.3 0.5 0.9 0.8 3.6 0.8 0.4 5.2 1.6 0.4 6.9 2.2 4.1 1.7 3.2 1.5 0.2 18.0 6.6 1.9 0.4 1.0 2.5 3.1 0.3 3.6 2.9 0.2 3.3 1.6 1.8 30.8 1.8 7.4 2.0 5.2 5.6 1.0 1.0 6.2 2.0 0.2 2.8 4.6 0.5 0.7 1.9 0.1 0.3 3.1 0.8 0.4 6.5 6.7 0.5 0.4 2.3 1.1 0.4 0.1 0.9 0.4 0.0 0.9 0.7 3.2 0.9 5.3 0.1 1.9 0.5 7.2 11.7 12.4 9.1 0.4 0.6 1.6 0.3 1.2 0.5 0.8 1.7 0.7 36.7 0.5 0.1 0.7 2.1 0.5 1.2 0.9 2.6 2.5 1.3 3.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.4 0.5 0.2 0.4 0.3 0.4 0.2 0.4 0.2 8.3 0.0 1.5 0.7 0.3 2.0 0.9 1.6 0.6 1.5 2.5 3.0 3.4 1.5 1.6 0.0 2.1 0.3 0.3 23.0 1.9 0.5 0.1 4.1 1.3 5.1 2.4 2.7 0.1 2.1 0.6 16.9 44.4 7.2 0.0 0.2 3.6 0.3 0.8 0.0 0.1 53.5 4.1 4.8 1.9 0.1 9.9 0.9 1.8 0.0 0.0 0.8 0.0 0.0 0.1 1.5 12.8 0.4 0.2 5.0 78.1 0.4 0.7 2.2 0.0 10.4 6.1 3.9 1.4 0.7 2.8 0.5 0.6 0.2 8.1 0.4 KCP "CRIM2, FLJ33365, NET67" ENSG00000135253 "Kielin cysteine rich BMP regulator" Q6ZWJ8 7 128862042-128910719 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 17.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 53.3;Early spermatids: 23.1;Late spermatids: 28.7;Proximal enterocytes: 55.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.5" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.3;HMC-1: 5.1;U-87 MG: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (6.12e-2)" "unprognostic (5.49e-2)" "unprognostic (1.45e-3)" "unprognostic (6.33e-3)" "unprognostic (2.14e-1)" "unprognostic (5.24e-3)" "unprognostic (2.01e-3)" "unprognostic (3.25e-3)" "unprognostic (9.59e-2)" "unprognostic (1.52e-1)" "unprognostic (2.20e-3)" "unprognostic (6.46e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (4.84e-2)" "unprognostic (7.64e-3)" 1.5 0.1 0.0 0.2 0.0 0.0 0.3 1.8 0.1 0.9 0.0 0.1 0.4 0.0 0.0 1.6 0.5 1.0 0.1 0.0 0.0 17.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.4 2.2 0.1 0.2 1.0 0.0 0.0 0.2 0.6 0.2 0.3 0.0 0.5 0.2 0.0 0.2 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 9.3 0.2 1.3 0.0 0.1 0.6 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.8 0.1 0.0 5.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 1.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.9 12.8 3.4 0.3 1.9 0.0 0.9 0.0 1.2 3.0 0.6 0.9 0.8 0.0 3.7 53.3 2.1 0.2 0.9 2.1 0.0 0.3 23.1 2.1 1.3 0.8 2.4 0.0 0.4 0.2 4.1 2.0 3.1 2.9 2.5 0.2 2.2 0.3 1.0 3.3 2.6 5.3 0.0 1.3 0.0 28.7 1.2 3.1 0.0 0.0 0.1 0.4 2.1 0.0 0.2 4.3 1.9 0.4 1.9 0.3 55.9 6.4 0.0 1.3 0.0 7.3 1.7 6.3 3.7 2.1 0.0 1.4 2.2 0.5 9.2 4.1 KERA "CNA2, SLRR2B" ENSG00000139330 Keratocan O60938 12 91050491-91058024 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Fibroblasts: 2.0" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "amygdala: 4.1;basal ganglia: 5.6;cerebral cortex: 6.2;hippocampal formation: 5.6" HPA039321 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 50: Fibroblasts - ECM organization" "HPA039321: AB_10795248" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (4.76e-3)" "unprognostic (3.65e-1)" "unprognostic (6.08e-2)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-3)" "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 KIAA0100 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, MGC111488" ENSG00000007202 KIAA0100 Q14667 17 28614446-28645454 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted to blood" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 36.1 30.7 22.4 28.5 20.7 31.5 30.6 18.2 23.5 22.7 31.7 30.8 19.7 23.1 25.7 31.3 29.2 20.5 24.2 24.4 21.3 43.0 18.6 30.7 28.4 29.9 24.4 23.9 24.4 51.8 25.2 29.6 29.3 27.1 34.8 27.5 28.9 27.1 51.9 31.8 26.7 35.3 20.2 28.8 23.3 24.9 26.5 32.3 35.4 42.5 34.9 30.3 16.0 20.6 66.5 123.8 61.4 58.8 109.3 64.8 44.8 60.9 80.1 72.3 67.6 85.9 29.4 92.0 71.2 111.2 75.3 86.2 91.4 89.6 87.1 102.8 88.7 73.2 95.9 47.2 47.0 129.1 121.3 66.5 68.2 98.0 74.1 56.1 104.9 64.1 70.6 29.0 66.8 94.4 94.5 61.1 26.9 119.0 46.6 71.7 69.0 60.0 43.4 116.9 60.2 46.5 76.8 205.5 50.7 76.0 123.2 88.6 98.1 55.0 60.4 74.5 116.2 27.2 33.8 58.0 62.8 81.7 65.4 0.3 1.1 1.5 1.2 1.0 1.2 1.1 0.5 1.0 1.3 0.6 0.6 0.7 0.7 0.8 1.2 2.9 0.7 0.7 22.4 20.7 18.2 23.5 24.4 21.3 29.9 24.4 29.3 20.2 26.5 20.6 21.5 16.0 17.8 15.0 16.5 10.3 8.9 8.7 15.4 31.7 19.3 14.7 30.2 14.3 13.0 12.9 29.2 15.3 34.4 30.5 5.9 9.9 19.4 20.4 16.1 16.4 12.1 14.1 19.1 11.0 9.4 14.1 21.4 16.4 8.2 20.4 18.5 30.5 10.6 28.6 18.3 16.4 8.2 31.5 18.6 23.2 9.3 19.9 10.6 14.0 25.3 14.3 21.6 11.6 12.7 9.8 12.1 6.4 17.1 15.8 17.9 15.1 15.1 22.5 0.0 20.3 20.1 30.5 28.1 22.9 11.1 45.6 17.0 24.2 22.6 11.7 KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.3;pituitary gland: 4.1" "Group enriched" "Detected in some" 8 "Astrocytes: 119.5;Early spermatids: 65.6;Excitatory neurons: 129.2;Inhibitory neurons: 72.7;Late spermatids: 96.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A-431: 2.0;A549: 2.0;GAMG: 2.1;HDLM-2: 2.4;HeLa: 1.9;SCLC-21H: 3.8;U-266/84: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA015607: AB_1852299, HPA076313: AB_2732308" "unprognostic (1.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (1.72e-2)" "unprognostic (4.65e-2)" "unprognostic (9.70e-2)" "unprognostic (2.21e-5)" "unprognostic (7.88e-4)" "unprognostic (9.53e-4)" "unprognostic (1.44e-6)" "unprognostic (1.20e-1)" "unprognostic (6.97e-2)" "unprognostic (3.13e-1)" "unprognostic (3.41e-2)" 0.0 0.4 10.0 0.2 10.3 0.0 0.1 4.3 10.4 0.1 0.6 0.4 0.0 0.0 0.0 0.0 1.6 0.2 0.0 9.2 5.8 0.0 0.0 0.6 0.0 7.2 7.4 0.0 1.4 0.1 4.1 0.0 7.6 0.4 0.4 1.2 0.2 0.0 0.0 0.7 0.2 0.1 2.7 0.2 0.8 1.1 12.3 0.0 0.0 0.0 0.1 0.0 0.0 4.8 2.0 2.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.6 0.9 0.0 2.1 0.8 0.3 0.0 0.0 2.4 1.0 0.0 1.9 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.1 3.8 0.2 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.4 0.3 3.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 10.0 10.3 4.3 10.4 9.2 5.8 7.2 7.4 7.6 2.7 12.3 4.8 0.1 3.2 0.5 119.5 0.6 0.0 0.0 0.5 0.0 3.6 0.1 0.1 1.4 0.0 1.5 0.0 0.0 0.0 0.0 1.4 0.0 0.4 65.6 2.6 0.1 0.0 10.2 0.0 129.2 0.0 0.0 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 72.7 0.8 0.0 0.0 0.0 96.8 0.6 0.2 0.0 5.6 0.6 0.3 0.0 5.0 3.1 0.3 0.1 0.7 0.0 0.2 0.0 0.1 10.9 0.9 0.0 0.1 0.0 1.2 1.5 0.0 0.0 0.7 0.1 0.1 0.3 0.3 KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "placenta: 233.1" "Cell type enriched" "Detected in many" 26 "Syncytiotrophoblasts: 1336.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.2" "Region enriched" "Detected in some" 6 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "BJ: 145.5;U-2 OS: 59.4" "Not detected" "Not detected" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" NA NA 860000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB017775: , HPA035542: AB_2674677" "unprognostic (9.64e-2)" "unprognostic (1.78e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.63e-1)" "unprognostic (8.98e-12)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "prognostic favorable (6.29e-6)" 0.0 0.0 0.4 0.0 0.8 0.0 0.1 0.6 0.6 0.3 0.8 0.2 0.9 0.2 0.0 0.1 0.1 0.0 0.1 0.4 10.7 2.4 4.3 1.3 0.0 1.8 0.3 0.0 1.0 0.0 3.1 233.1 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.1 1.3 0.2 0.2 2.0 3.2 5.2 1.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.4 145.5 1.8 2.5 0.7 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.2 0.0 0.2 0.1 0.0 0.0 0.9 0.2 0.1 0.0 0.7 0.0 0.8 0.2 0.3 0.0 0.1 59.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.6 0.6 0.4 10.7 1.8 0.3 0.4 0.2 1.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 4.0 7.5 0.0 1.0 1.2 0.6 0.0 1.5 2.2 0.0 0.0 9.3 0.0 1.5 0.0 11.3 40.2 0.2 0.0 1.4 0.0 0.0 0.1 4.9 6.9 1.9 4.1 0.5 0.0 0.4 0.7 2.8 15.1 0.0 0.0 0.6 0.0 0.0 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.5 0.0 0.1 50.1 17.0 1.4 0.4 0.0 0.0 0.0 7.1 0.6 1.1 0.0 0.0 1336.6 0.1 0.1 2.1 14.3 KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 123.3" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 2.4;SK-BR-3: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 3.3 1.4 0.9 0.8 3.1 0.1 2.5 0.8 1.5 1.8 47.1 2.1 2.7 1.2 8.8 1.1 0.8 1.3 1.1 4.2 1.1 128.7 0.4 3.5 1.0 0.5 0.5 0.1 1.2 135.2 0.3 30.4 0.5 8.0 0.9 0.0 0.8 2.5 0.7 0.6 2.6 1.2 0.6 2.4 2.0 0.5 0.8 0.5 1.3 1.5 0.5 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.1 0.8 1.5 4.2 1.1 0.5 0.5 0.5 0.6 0.8 0.5 15.8 0.0 0.5 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.7 12.9 0.0 0.2 0.0 0.4 5.9 0.0 1.8 0.1 2.5 10.2 16.3 0.4 1.2 0.0 0.1 1.6 0.0 0.1 0.0 0.1 1.1 0.2 2.8 0.0 0.5 1.1 0.0 0.9 1.0 0.8 0.3 1.9 0.0 6.5 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.6 1.8 123.3 0.7 0.0 0.0 1.1 2.3 1.4 0.5 0.0 0.1 0.1 1.1 0.1 1.9 0.1 KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819146-50823787 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 84 "pancreas: 9557.9;salivary gland: 5487.3" "Group enriched" "Detected in many" 7 "Exocrine glandular cells: 788.4;Intestinal goblet cells: 1317.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 9.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 13 "B-cells: 9.5" "Cell line enriched" "Detected in some" 4 "RPMI-8226: 43.8" HPA059690 Approved "Secreted to digestive system" NA NA 10000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA059690: " "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" 1.4 2.4 0.1 4.0 0.0 0.4 1.8 0.0 0.4 1.9 0.0 68.8 9.6 2.0 0.0 1.3 0.6 0.1 3.0 0.3 0.0 89.4 0.6 0.5 0.5 0.0 0.0 4.7 9557.9 0.4 0.2 1.1 0.0 2.7 53.0 0.0 5487.3 0.1 0.2 26.3 9.7 2.8 0.0 3.3 1.4 0.1 0.0 0.2 2.9 0.2 1.5 0.2 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.4 0.2 0.3 0.5 1.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.1 0.1 0.4 0.2 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.0 0.0 9.7 0.0 0.1 0.0 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 9.5 0.0 0.0 0.1 4.0 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 18.9 19.5 1.2 2.9 1.2 0.0 1.0 1.1 0.3 0.0 2.5 0.0 0.0 0.0 0.2 62.2 45.0 3.3 0.6 0.1 1.4 0.4 117.1 0.0 0.0 788.4 0.0 7.7 1.5 0.0 8.9 8.8 0.4 0.0 0.6 0.0 0.0 1317.5 14.2 1.6 5.3 0.3 6.2 1.5 5.4 0.0 6.2 0.0 0.0 0.0 0.0 125.8 134.4 0.0 10.9 9.8 57.1 0.3 0.3 0.0 0.0 0.0 1.1 0.3 0.9 1.7 54.0 0.0 2.1 2.5 148.5 3.8 KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 111.8;esophagus: 412.5;vagina: 190.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Basal respiratory cells: 61.4;Club cells: 113.9;Pancreatic endocrine cells: 74.8;Prostatic glandular cells: 68.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 67.2;HaCaT: 158.7;OE19: 68.1" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" 8.6 0.6 0.7 0.2 0.4 0.6 6.2 1.2 0.4 111.8 1.0 1.5 0.3 1.7 0.2 412.5 8.6 3.5 1.3 0.3 1.4 0.6 0.3 8.7 0.0 2.6 1.7 19.7 0.6 0.2 1.5 0.2 2.8 7.2 0.6 0.3 55.2 0.5 0.2 65.7 2.6 0.6 0.7 0.2 1.8 6.0 1.0 0.3 0.6 0.1 18.8 0.6 190.6 0.4 21.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 67.2 0.0 6.6 0.0 0.1 158.7 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 68.1 0.6 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.4 1.2 0.4 0.3 1.4 2.6 1.7 2.8 0.7 1.0 0.4 0.3 32.1 2.6 0.0 0.0 7.5 15.6 61.4 9.1 1.0 12.3 14.0 0.7 8.6 113.9 0.0 0.0 0.0 0.2 1.2 0.0 7.5 0.3 2.1 1.0 1.7 0.0 0.0 0.1 15.4 0.0 6.0 1.1 8.0 0.0 0.1 1.1 0.0 0.1 0.0 0.6 0.0 22.4 0.0 0.6 0.6 11.5 0.5 0.0 0.0 0.6 0.3 0.0 0.0 0.5 74.8 0.0 6.0 0.0 68.6 0.0 0.0 15.8 0.5 0.0 0.4 2.6 1.0 1.6 28.0 4.3 0.0 0.5 0.5 0.0 29.6 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.2;skin 1: 239.8;vagina: 186.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 152.1;Club cells: 217.9;Late spermatids: 339.0;Prostatic glandular cells: 234.8;Squamous epithelial cells: 176.4;Suprabasal keratinocytes: 217.1;Urothelial cells: 186.1" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;HaCaT: 41.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" NA NA 1800000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 28.4 0.2 0.0 0.4 0.0 0.0 17.1 0.9 0.1 109.8 44.5 1.9 0.7 7.2 2.6 324.2 34.2 59.3 2.0 1.7 0.0 0.3 0.8 18.9 0.0 0.2 0.1 1.6 89.1 0.0 8.8 0.0 0.3 64.9 0.6 0.7 169.5 4.2 1.9 239.8 1.4 0.3 0.0 0.1 113.3 14.4 0.6 2.5 0.4 0.3 27.2 1.4 186.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.4 0.1 13.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.7 0.0 0.2 0.1 0.3 0.0 0.6 0.0 0.2 86.6 10.4 0.0 0.4 106.9 152.1 131.6 13.1 0.2 33.4 35.3 0.8 88.6 217.9 0.0 0.0 0.0 0.0 0.1 0.0 9.2 111.6 4.7 1.1 3.8 20.3 0.0 0.0 130.2 0.0 9.1 91.3 15.6 1.3 0.0 0.0 0.0 0.3 0.0 0.0 10.7 118.0 0.0 11.4 339.0 2.8 1.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 79.4 0.0 0.4 0.5 234.8 0.1 0.0 26.9 1.3 0.0 0.2 7.9 2.1 2.5 176.4 217.1 0.0 1.7 0.0 0.4 186.1 KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "cervix: 108.5;esophagus: 208.6;salivary gland: 64.7;vagina: 99.4" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Enteroendocrine cells: 40.3;Intestinal goblet cells: 24.9;Ionocytes: 14.2;Late spermatids: 34.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025473 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favorable (8.01e-4)" "unprognostic (8.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 108.5 2.2 2.1 4.0 0.0 0.0 208.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.1 0.5 0.8 0.0 64.7 0.0 0.0 0.6 5.8 0.1 0.0 0.0 0.4 0.5 0.0 0.1 0.1 0.0 8.9 0.0 99.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.5 0.5 0.2 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 30.7 0.0 0.0 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 14.2 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.2 8.4 0.0 0.0 0.0 0.0 1.3 1.7 KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51055626-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 519.9" "Group enriched" "Detected in some" 4 "Late spermatids: 246.9;Squamous epithelial cells: 68.3" "Group enriched" "Detected in many" 4 "cervical cancer: 20.6;head and neck cancer: 42.3;melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HaCaT: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA062136: AB_2684694" "unprognostic (1.99e-3)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-2)" "unprognostic (2.18e-2)" "unprognostic (8.30e-2)" "unprognostic (7.07e-6)" "unprognostic (7.33e-2)" "unprognostic (2.53e-1)" "unprognostic (6.38e-2)" "unprognostic (7.06e-2)" 0.2 0.2 0.1 0.2 0.1 0.0 1.6 0.1 0.2 96.3 0.9 0.6 1.6 0.5 0.4 519.9 0.5 1.1 0.2 0.1 0.1 0.1 0.2 0.7 0.0 0.2 0.5 0.2 4.4 0.4 0.3 0.0 0.1 0.6 0.1 0.0 74.9 0.0 0.1 10.8 0.8 0.3 0.1 0.1 1.4 4.3 0.1 0.2 0.3 0.0 63.5 0.2 122.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 27.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.6 1.1 4.0 0.0 0.9 1.9 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.1 0.1 0.3 1.8 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.3 246.9 0.3 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.7 68.3 1.3 0.0 0.4 0.4 0.0 2.1 KLK14 KLK-L6 ENSG00000129437 "Kallikrein related peptidase 14" Q9P0G3 19 51077495-51084245 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 9.7" "Cell type enhanced" "Detected in single" "Club cells: 2.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.7;HEK 293: 2.9;U-266/84: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" CAB026228 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "CAB026228: " "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.44e-2)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (6.12e-2)" "unprognostic (4.91e-2)" "unprognostic (5.79e-2)" "unprognostic (7.84e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (8.87e-2)" "unprognostic (2.04e-8)" "unprognostic (1.93e-1)" "unprognostic (3.74e-3)" "unprognostic (1.94e-2)" "unprognostic (8.08e-2)" 0.5 0.3 2.1 0.2 2.2 0.1 1.6 2.3 3.3 4.2 1.9 0.4 1.3 0.5 0.6 0.9 0.7 0.3 0.8 2.2 1.7 0.5 0.3 0.4 0.3 2.1 1.9 1.1 0.7 0.0 0.6 0.0 2.2 0.8 0.3 0.6 0.8 0.5 0.3 9.7 0.7 0.1 1.6 0.6 0.6 0.9 2.0 0.3 0.4 0.1 0.5 0.6 3.9 2.3 1.4 0.5 0.1 0.6 0.4 0.4 0.6 0.1 0.0 0.0 0.1 1.2 1.4 0.6 0.4 0.2 0.3 10.7 0.1 0.2 0.0 0.3 2.9 0.2 0.9 0.0 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.1 0.1 0.4 0.2 0.3 0.0 0.9 0.2 0.5 0.6 1.2 1.1 0.1 0.1 0.6 0.0 0.6 0.1 0.0 0.2 1.0 0.3 0.2 0.4 0.0 0.0 0.1 0.4 0.6 0.2 2.6 5.5 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.3 3.3 2.2 1.7 2.1 1.9 2.2 1.6 2.0 2.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLK15 "ACO, HSRNASPH, prostinogen" ENSG00000174562 "Kallikrein related peptidase 15" Q9H2R5 19 50825289-50837213 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.2;salivary gland: 5.6" "Cell type enhanced" "Detected in some" "Early spermatids: 5.5;Intestinal goblet cells: 34.6;Late spermatids: 8.8;Spermatocytes: 15.0;Spermatogonia: 9.5" "Group enriched" "Detected in some" 4 "prostate cancer: 3.5;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA019802 Uncertain "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA019802: AB_1852601" "unprognostic (6.06e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-2)" "unprognostic (2.90e-1)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.2 0.0 5.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.5 0.0 0.0 0.1 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 34.6 0.0 0.0 0.0 8.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 9.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 87 "prostate: 566.2" "Cell type enriched" "Detected in some" 40 "Prostatic glandular cells: 777.2" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 3.5;NB-4: 5.6" HPA000764 Supported "Secreted in male reproductive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.7 1.1 3.2 1.2 2.3 6.4 0.5 5.2 4.3 0.2 2.2 0.4 1.5 0.6 1.1 0.5 0.3 0.2 0.3 2.6 2.2 0.4 0.8 0.5 1.0 2.2 3.1 0.4 0.0 0.8 0.0 0.2 2.9 566.2 0.3 1.7 1.9 0.4 1.0 0.8 1.0 0.1 0.6 0.7 0.5 3.0 2.4 0.0 1.9 0.0 0.2 0.2 0.0 6.3 0.9 0.6 0.3 0.7 0.0 0.4 3.5 0.2 0.1 0.1 0.1 0.3 0.4 1.0 0.1 0.0 0.3 0.9 0.1 0.0 0.1 0.9 0.6 0.0 0.7 0.0 0.0 0.1 1.7 0.2 0.1 0.1 0.2 0.2 0.0 0.6 0.7 0.9 0.2 1.0 0.6 5.6 0.5 0.9 0.0 0.4 0.0 1.6 0.0 1.1 0.5 0.5 0.1 0.7 0.6 0.1 0.5 0.2 0.4 0.6 1.0 2.6 0.9 0.8 1.8 0.4 1.0 0.6 0.7 0.4 0.6 0.5 0.3 0.3 0.2 0.3 0.2 0.3 0.1 0.6 0.2 0.4 1.7 0.4 0.2 0.5 0.1 0.2 3.2 2.3 5.2 4.3 2.6 2.2 2.2 3.1 2.9 0.6 2.4 6.3 0.0 0.0 0.6 0.0 0.2 0.3 10.2 0.0 0.0 0.0 16.1 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 5.2 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 777.2 0.0 0.1 0.0 0.0 0.0 0.0 1.8 19.3 7.2 0.0 0.9 0.0 0.6 1.7 0.0 12.0 KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 320 "prostate: 8011.8" "Cell type enriched" "Detected in some" 77 "Prostatic glandular cells: 3438.6" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 173 "BEWO: 31.7;NB-4: 27.8;RPMI-8226: 19.3;SH-SY5Y: 10.5;U-2197: 10.7" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" NA NA 7000000 "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" 4.3 7.6 0.0 5.6 0.0 0.0 9.0 0.0 0.0 0.5 0.0 2.6 4.8 1.6 14.4 0.2 4.0 0.0 0.5 0.0 0.0 1.4 1.5 1.2 1.7 0.0 0.0 0.3 0.9 0.6 0.2 0.3 0.0 8011.8 1.1 0.0 4.5 25.0 0.3 0.5 3.7 0.0 0.0 0.2 1.0 6.9 0.0 0.0 0.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 19.3 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 12.4 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.4 2.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.1 9.0 0.0 0.0 0.0 1.8 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3438.6 0.1 0.1 0.0 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.0 0.0 4.2 0.2 0.4 44.6 KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906352-50910738 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 32 "prostate: 286.4" "Cell type enriched" "Detected in some" 15 "Prostatic glandular cells: 106.1" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.4;HaCaT: 7.9;OE19: 7.3;SK-BR-3: 5.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.5" HPA051839 Enhanced "Secreted in male reproductive system" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" "HPA051839: AB_2681632" "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" 0.4 2.9 0.4 1.5 0.3 1.1 1.7 1.7 1.2 6.5 0.0 3.0 7.3 4.4 1.1 2.1 0.6 1.0 0.1 0.3 0.8 0.6 1.2 0.3 0.8 1.6 0.8 0.1 0.9 1.0 0.0 0.3 1.6 286.4 3.6 0.5 4.8 2.7 3.5 8.9 5.1 0.3 0.5 0.3 1.9 1.2 0.6 0.1 3.8 1.3 0.8 1.2 0.2 0.5 4.1 1.6 0.2 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.5 6.4 0.4 0.3 0.1 0.2 7.9 0.0 4.2 0.0 1.1 1.1 1.3 3.8 1.4 0.0 1.4 1.7 0.0 1.9 0.0 0.0 0.2 0.0 0.3 0.7 3.3 0.0 1.0 0.1 2.0 0.1 7.3 0.3 0.3 0.4 0.9 0.0 2.6 0.0 0.4 0.3 5.1 0.0 0.2 4.0 0.3 0.9 0.2 0.2 1.0 0.2 2.0 0.9 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.7 1.2 0.3 0.8 1.6 0.8 1.6 0.5 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.6 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 0.0 0.0 0.0 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 106.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 3.3 1.0 2.6 KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 202.7" "Group enriched" "Detected in some" 4 "Early spermatids: 85.4;Late spermatids: 193.2" "Group enriched" "Detected in many" 5 "head and neck cancer: 73.1;melanoma: 32.1;ovarian cancer: 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "A-431: 485.1;HaCaT: 455.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014343, CAB025503, CAB026341, HPA073512" Enhanced "Secreted in other tissues" NA NA 2500000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "CAB025503: , CAB026341: , HPA014343: AB_1852603, HPA073512: " "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavorable (3.85e-6)" 4.6 0.0 1.1 0.0 1.1 0.0 30.2 0.4 2.6 15.6 0.6 0.0 0.1 0.1 0.0 23.0 0.5 0.0 0.2 1.1 0.8 0.5 0.1 6.1 0.0 1.0 1.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 23.6 0.0 1.1 202.7 0.0 0.0 0.5 0.3 0.0 14.2 1.6 0.1 0.1 0.0 0.6 0.0 13.5 0.7 485.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.1 455.4 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 1.1 0.0 1.5 0.1 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.4 2.6 1.1 0.8 1.0 1.0 1.0 0.5 1.6 0.7 0.2 16.0 0.0 0.0 0.0 26.8 1.8 2.4 12.0 0.0 33.0 27.2 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 85.4 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 193.2 1.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 1.6 0.8 2.8 10.9 0.0 0.3 0.0 0.0 0.1 KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 253.0;esophagus: 94.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 23.9;Breast myoepithelial cells: 16.1;Collecting duct cells: 11.0;Oligodendrocytes: 87.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 575.5;CAPAN-2: 1346.5" "Region enhanced" "Detected in all" "pons and medulla: 167.8" "Region enhanced" "Detected in many" "spinal cord: 371.7" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" Yes No 10000000 "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (1.27e-4)" 0.2 0.0 71.8 0.0 135.8 0.0 7.2 170.8 119.8 53.1 45.6 0.1 0.2 1.5 0.4 94.2 28.9 3.5 0.0 72.9 94.3 20.4 0.0 0.0 0.0 213.8 130.8 0.8 0.0 0.0 0.7 0.0 182.1 0.1 0.0 0.0 15.8 2.2 0.0 9.9 0.0 0.0 123.6 5.8 0.1 0.9 118.1 1.5 0.0 0.0 36.4 0.0 27.4 253.0 575.5 0.0 0.0 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 67.7 1346.5 0.0 8.1 0.0 0.6 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.1 131.0 2.2 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 5.6 18.2 1.0 1.9 0.0 1.1 46.3 0.0 1.3 0.0 0.4 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 135.8 170.8 119.8 72.9 94.3 213.8 130.8 182.1 123.6 118.1 253.0 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 0.0 23.9 16.1 0.3 0.0 1.7 11.0 0.0 0.1 0.4 0.0 0.0 0.1 2.3 0.6 7.5 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 87.9 7.8 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 1.6 0.0 0.3 0.1 0.0 0.0 2.4 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Basal keratinocytes: 5.0;Basal squamous epithelial cells: 4.6;Breast glandular cells: 9.4;Breast myoepithelial cells: 10.4;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 10.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.0;CAPAN-2: 8.0;HaCaT: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 7.1 0.1 8.4 0.1 9.2 0.3 11.2 0.9 7.4 19.7 1.0 0.1 0.5 0.7 0.2 94.7 16.3 1.3 0.2 6.5 1.4 12.1 0.1 3.1 0.0 4.3 1.4 0.1 0.1 0.3 0.7 0.0 4.9 0.1 0.0 0.1 21.6 0.2 1.0 201.2 0.0 0.2 2.1 0.8 0.3 0.3 7.4 0.9 0.2 0.0 10.9 0.0 30.9 3.0 5.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.8 8.0 0.0 1.1 0.0 0.1 31.7 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 8.4 9.2 0.9 7.4 6.5 1.4 4.3 1.4 4.9 2.1 7.4 3.0 0.0 6.4 1.1 0.0 0.0 5.0 0.1 0.5 4.6 0.0 9.4 10.4 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 5.9 10.7 0.0 0.1 0.0 0.1 2.7 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 66.0;Suprabasal keratinocytes: 180.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 88.3;CAPAN-2: 112.2;HaCaT: 83.5" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 5.7 0.0 0.1 0.0 0.0 0.0 8.4 0.8 0.7 24.7 0.2 0.0 0.0 0.9 0.4 118.0 13.2 0.1 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.7 0.2 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 17.1 0.1 0.7 87.1 0.0 0.1 0.0 0.2 0.1 1.2 0.2 1.1 0.5 0.0 9.6 0.0 47.2 0.5 88.3 0.0 0.0 0.6 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.7 112.2 0.0 2.2 0.0 0.1 83.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 10.3 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.7 0.0 0.0 0.7 0.2 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.3 66.0 0.0 0.4 14.8 0.0 13.0 15.6 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.7 11.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 5.0 1.8 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 2.8 6.2 21.1 180.1 0.0 0.2 0.0 0.2 0.1 KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51002508-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.0" CAB025049 Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "CAB025049: " "unprognostic (3.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186208979-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 328.4" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 280.5" "Cancer enriched" "Detected in some" 17 "liver cancer: 27.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SCLC-21H: 2.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 28900000000 5300000000 "Cluster 62: Liver - Hemostasis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (4.80e-2)" "unprognostic (4.53e-3)" "unprognostic (4.36e-2)" "unprognostic (4.17e-2)" "unprognostic (5.93e-2)" "unprognostic (1.90e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-1)" "unprognostic (8.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (7.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" 0.6 1.8 5.9 0.3 6.5 0.0 0.6 6.0 7.6 1.4 9.3 2.3 2.8 0.6 1.0 0.4 1.3 2.5 2.6 6.3 6.2 7.7 328.4 1.0 0.7 7.0 6.5 0.7 4.8 1.0 3.6 0.2 6.4 1.7 1.4 13.1 0.7 0.6 2.4 0.3 2.6 0.6 6.1 2.4 0.8 2.0 6.0 0.4 1.9 1.8 0.4 1.5 0.9 6.3 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.5 6.0 7.6 6.3 6.2 7.0 6.5 6.4 6.1 6.0 6.3 0.1 0.0 0.0 48.3 0.7 0.0 0.1 0.2 0.6 5.1 0.3 0.5 4.3 14.3 0.1 1.8 16.7 0.0 0.5 0.6 0.0 1.8 2.8 0.6 0.2 1.0 3.0 2.7 10.2 0.5 0.0 0.4 0.0 0.4 0.0 0.2 5.7 280.5 0.2 0.0 15.6 0.4 0.0 4.4 0.0 2.2 0.6 0.3 0.0 6.5 0.1 10.6 2.1 8.0 7.7 0.4 1.4 0.0 0.1 0.0 2.6 1.6 1.1 5.1 0.0 0.6 0.3 1.3 1.3 0.1 0.0 0.0 0.6 0.1 0.7 0.1 KNG1 "BDK, BK, KNG" ENSG00000113889 "Kininogen 1" P01042 3 186717348-186744410 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis, Inflammatory response" "Protease inhibitor, Thiol protease inhibitor, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 3195.2" "Group enriched" "Detected in some" 25 "Distal tubular cells: 655.4;Hepatocytes: 1816.9" "Cancer enriched" "Detected in some" 126 "liver cancer: 608.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;Hep G2: 1.7;RH-30: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001616, HPA001645, CAB009809" Enhanced "Secreted to blood" NA NA 90000000000 47000000000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "CAB009809: AB_2134781, HPA001616: AB_1079216, HPA001645: AB_1079215" "unprognostic (3.88e-1)" "unprognostic (1.63e-1)" "unprognostic (2.82e-1)" "unprognostic (3.27e-1)" "unprognostic (8.30e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.28e-6)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (9.96e-2)" "unprognostic (1.65e-1)" "unprognostic (3.45e-3)" "unprognostic (5.20e-2)" "unprognostic (2.46e-1)" "unprognostic (4.52e-2)" 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 464.1 3195.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 5.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 48.6 0.0 33.1 0.0 0.0 0.0 1.8 655.4 0.0 0.4 0.0 0.0 1.5 0.0 40.2 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 30.0 1816.9 0.1 0.0 0.8 0.1 0.0 47.2 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.5 0.1 1.1 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 2.7 0.0 0.1 0.1 KRT10 "CK10, K10, KPP" ENSG00000186395 "Keratin 10" P13645 17 40818117-40822614 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "skin 1: 15851.5" "Cell type enriched" "Detected in all" 5 "Suprabasal keratinocytes: 12515.3" "Group enriched" "Detected in all" 4 "head and neck cancer: 310.0;melanoma: 562.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "hTCEpi: 718.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000132, HPA012014" Enhanced "Secreted in other tissues" NA NA 18000000000 "Cluster 37: B-cells - Transcription" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB000132: , HPA012014: AB_1852195" "unprognostic (3.07e-1)" "unprognostic (5.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.60e-1)" "unprognostic (3.02e-2)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-2)" "unprognostic (8.10e-2)" 66.1 47.9 9.4 7.6 9.8 13.4 432.0 9.9 14.9 548.0 10.4 45.2 7.9 55.0 5.5 78.6 45.5 2.2 95.7 9.9 9.8 67.2 64.5 39.7 6.2 9.8 9.7 52.3 69.1 8.2 77.2 3.8 9.8 60.0 3.4 6.9 163.9 5.5 123.1 15851.5 48.2 4.0 9.8 56.8 58.0 64.9 9.8 44.0 53.5 5.8 13.7 48.5 1106.2 10.4 30.3 31.2 11.0 12.2 14.4 11.5 10.4 29.9 16.5 11.4 10.6 11.2 11.7 8.7 42.0 13.1 16.2 158.5 5.4 11.3 13.4 20.1 27.0 9.2 44.7 19.4 16.4 17.1 24.9 10.1 718.0 9.0 17.3 15.0 7.4 12.3 102.1 16.0 12.2 17.3 25.5 16.2 14.6 23.1 19.1 17.8 16.7 17.7 12.3 26.3 8.9 11.1 19.9 46.0 39.0 17.3 35.5 24.3 9.3 17.6 29.5 22.5 34.4 0.4 19.8 22.4 24.5 10.4 23.4 12.8 2.6 11.1 4.8 2.3 5.4 11.2 5.4 6.8 4.1 5.6 5.8 5.9 0.8 6.9 3.2 8.1 5.5 1.9 9.4 9.8 9.9 14.9 9.9 9.8 9.8 9.7 9.8 9.8 9.8 10.4 197.8 35.3 40.0 19.2 187.5 2239.7 320.6 370.2 255.6 47.0 304.4 328.2 194.2 174.5 197.2 112.2 20.9 117.4 163.2 138.9 305.2 232.5 150.4 174.3 172.2 170.0 181.1 87.7 19.1 376.9 295.7 204.5 126.9 164.5 74.3 87.0 159.5 237.6 105.0 21.9 16.3 237.6 195.3 90.3 350.7 65.6 216.6 116.8 393.1 20.6 100.1 221.4 162.7 17.6 35.0 236.0 149.8 174.9 311.6 342.0 155.3 233.2 116.8 68.6 105.2 141.0 167.7 345.1 121.2 295.0 12515.3 160.1 164.3 131.4 173.1 515.6 KRTDAP "KDAP, UNQ467" ENSG00000188508 "Keratinocyte differentiation associated protein" P60985 19 35487324-35495558 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skin 1: 6146.5;vagina: 1735.6" "Cell type enriched" "Detected in some" 15 "Suprabasal keratinocytes: 5277.0" "Group enriched" "Detected in many" 7 "head and neck cancer: 486.4;melanoma: 207.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "hTCEpi: 100.2" "Region enriched" "Detected in single" 6 "white matter: 1.6" "Not detected" "Not detected" HPA063474 Enhanced "Secreted in other tissues" NA NA 34000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA063474: AB_2685019" "unprognostic (4.55e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-1)" "unprognostic (6.11e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (3.80e-2)" "unprognostic (1.50e-1)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" 5.5 1.0 1.0 0.0 1.6 1.8 406.4 0.9 1.8 845.7 1.1 1.8 0.1 0.8 0.7 111.0 1.3 0.0 2.5 1.0 1.0 0.8 3.0 1.7 0.0 1.1 0.9 1.7 3.4 0.7 1.3 0.0 1.2 1.6 0.0 0.1 205.3 0.3 22.5 6146.5 1.3 0.1 1.0 0.8 1.5 3.3 0.9 20.0 2.5 0.3 90.1 0.7 1735.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.2 0.0 0.0 0.4 100.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.6 0.9 1.8 1.0 1.0 1.1 0.9 1.2 1.0 0.9 1.0 0.3 0.0 0.0 0.0 0.0 348.5 0.8 0.4 0.0 0.0 0.5 1.5 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 18.4 0.2 0.1 3.6 0.0 0.0 0.1 0.2 0.0 4.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.7 63.4 0.9 0.1 42.7 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 2.4 42.9 19.1 0.0 5277.0 0.0 1.5 0.0 0.0 0.5 LACRT LACRITIN ENSG00000135413 Lacritin Q9GZZ8 12 54630811-54634895 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "salivary gland: 13.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 304 "breast cancer: 15.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 230000 "Cluster 24: Salivary gland - Salivary secretion" 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 362.1;skin 1: 215.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 174.7;Ductal cells: 178.0;monocytes: 248.6;Pancreatic endocrine cells: 227.0;Proximal enterocytes: 214.7;Squamous epithelial cells: 265.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 159.9;CAPAN-2: 158.5;HaCaT: 220.4;HBEC3-KT: 190.3;hTCEpi: 181.5;MCF7: 218.3;OE19: 246.5;RT4: 164.7;SK-BR-3: 250.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" 0.5 0.1 0.0 15.9 0.1 0.1 15.8 0.0 0.2 65.4 0.0 67.6 75.6 5.0 11.0 362.1 14.7 50.2 8.4 0.2 0.6 38.6 21.6 10.6 2.9 0.0 0.0 0.4 50.7 2.4 0.7 4.1 0.0 15.7 51.0 0.0 51.9 22.6 5.1 215.4 74.5 2.9 0.0 1.4 66.9 0.3 0.0 6.2 3.5 0.2 47.7 71.4 135.2 0.0 159.9 1.3 0.0 0.3 0.0 0.0 57.0 0.0 0.0 0.1 0.1 127.3 158.5 0.0 8.9 0.0 0.0 220.4 0.0 190.3 0.1 0.2 0.0 0.0 0.1 79.3 0.0 0.1 0.2 0.1 181.5 0.1 36.8 0.0 0.1 0.0 0.1 0.7 0.1 218.3 0.2 0.4 3.7 246.5 2.6 0.2 7.4 2.3 126.0 164.7 9.1 0.2 0.1 250.6 3.1 5.4 37.6 0.4 0.0 0.1 0.5 0.5 0.6 0.1 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 35.4 0.0 0.9 88.5 112.1 47.2 46.7 0.0 15.4 14.1 2.1 110.1 31.3 31.3 0.0 3.8 0.5 174.7 45.0 178.0 1.1 26.2 2.6 1.6 18.1 0.0 0.0 121.9 5.9 2.6 85.1 34.5 0.0 0.0 0.4 9.0 0.5 0.0 0.0 53.8 18.3 0.6 16.0 3.6 0.0 2.6 10.6 0.0 248.6 0.0 0.0 0.0 0.0 227.0 109.6 0.4 2.9 77.1 214.7 71.8 4.8 0.0 0.0 0.0 3.2 0.0 0.3 265.6 152.7 10.4 1.5 0.0 136.2 150.2 LAIR2 CD306 ENSG00000167618 "Leukocyte associated immunoglobulin like receptor 2" Q6ISS4 19 54497879-54510687 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.6;pituitary gland: 2.6" "Cell type enriched" "Detected in some" 7 "Extravillous trophoblasts: 696.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "gdT-cell: 14.0;memory CD4 T-cell: 13.8;memory CD8 T-cell: 19.5;naive CD8 T-cell: 13.2;T-reg: 49.5" "Lineage enriched" "Detected in many" 40 "T-cells: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Hep G2: 1.0" "Low region specificity" "Detected in some" "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.99e-3)" "unprognostic (7.49e-2)" "unprognostic (4.19e-2)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (4.86e-4)" "unprognostic (1.06e-2)" "unprognostic (8.37e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" "unprognostic (3.68e-9)" "unprognostic (1.21e-2)" "unprognostic (3.15e-3)" "unprognostic (3.40e-5)" "unprognostic (6.71e-2)" 0.2 0.0 0.1 0.4 0.3 0.8 0.1 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.1 0.7 1.6 0.2 0.2 0.0 0.1 0.0 2.6 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.1 0.3 0.3 0.4 0.6 0.1 0.2 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 14.0 0.1 0.4 0.0 13.8 19.5 0.1 0.1 2.4 13.2 0.2 1.2 0.3 0.1 49.5 7.8 0.1 0.3 0.1 0.7 0.3 0.3 0.2 0.2 0.4 0.1 0.4 0.5 0.8 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.0 10.7 95.4 0.9 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.2 696.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.8 1.8 0.0 0.5 0.0 46.4 0.0 0.1 0.6 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 32.2 23.2 0.0 0.0 0.0 LALBA LYZL7 ENSG00000167531 "Lactalbumin alpha" P00709 12 48567684-48570066 "Cancer-related genes, Metabolic proteins, Predicted secreted proteins" "Lactose biosynthesis" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 926 "breast: 2187.5" "Cell type enriched" "Detected in some" 160 "Breast glandular cells: 48911.9" "Cancer enriched" "Detected in single" 599 "breast cancer: 29.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026343, HPA029855, HPA029856" Enhanced "Secreted in female reproductive system" NA NA 91000 "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "CAB026343: , HPA029855: AB_2673222, HPA029856: AB_10671362" "unprognostic (7.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 2187.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.6 0.0 0.0 0.0 46.7 0.0 0.0 0.0 0.0 0.0 48911.9 305.6 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.0 0.6 0.0 0.0 15.9 0.0 0.0 0.1 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 58.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.7 0.0 0.0 0.0 32.6 0.0 0.0 0.0 LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Distal enterocytes: 173.6;Granulosa cells: 77.3;Intestinal goblet cells: 44.2;Paneth cells: 35.8;Proximal enterocytes: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 56.0;ASC diff: 41.0;BEWO: 199.6;hTEC/SVTERT24-B: 41.7;SK-MEL-30: 38.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB010179 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" 0.7 0.0 2.0 0.2 1.5 0.0 1.6 1.9 1.1 0.8 0.5 0.1 0.0 0.9 1.4 0.1 0.2 0.0 0.2 2.0 2.0 2.9 0.1 0.3 0.0 2.0 2.8 1.4 1.1 0.0 1.0 0.1 2.1 0.2 0.0 0.4 1.3 0.6 0.0 0.2 0.0 0.3 2.2 0.1 0.0 5.9 3.0 0.1 2.5 0.0 0.0 0.3 0.2 2.9 0.0 0.0 56.0 0.0 41.0 36.5 199.6 2.0 9.8 9.9 21.5 24.4 0.0 0.0 0.5 3.4 8.0 0.1 0.0 7.3 4.1 0.0 3.2 0.0 11.8 0.0 4.8 0.0 0.0 31.1 1.1 41.7 23.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 2.8 0.0 0.0 38.4 11.6 0.0 0.0 0.0 7.5 20.5 4.2 0.1 0.0 0.0 0.0 3.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 1.9 1.1 2.0 2.0 2.0 2.8 2.1 2.2 3.0 2.9 2.6 6.4 0.0 90.8 0.0 0.0 0.8 0.8 0.6 0.5 2.3 7.2 1.9 4.3 0.0 0.0 0.0 4.1 0.0 173.6 0.0 0.0 1.6 4.1 0.6 0.2 1.2 0.0 1.4 0.5 3.1 4.2 0.0 4.3 0.0 77.3 0.0 0.1 0.9 0.0 1.7 44.2 0.0 0.0 0.0 3.7 0.0 0.2 0.0 15.0 0.0 3.4 0.0 4.0 1.8 0.0 35.8 0.0 0.0 1.0 47.5 1.4 0.1 0.3 0.0 0.6 3.4 0.4 2.5 0.3 0.0 4.8 0.2 4.6 16.5 0.3 LAMA2 LAMM ENSG00000196569 "Laminin subunit alpha 2" P24043 6 128883138-129516566 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 106.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 363.1;Fibroblasts: 151.1;Leydig cells: 184.2;Microglial cells: 692.3;Oligodendrocytes: 160.9;Peritubular cells: 224.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 255.1;ASC TERT1: 184.5;HHSteC: 55.5;HSkMC: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB040310, CAB078182" Enhanced "Secreted to extracellular matrix" NA NA 55000000 "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB040310: , CAB078182: AB_2665829" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (2.17e-2)" "unprognostic (3.17e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (9.73e-2)" "unprognostic (3.67e-2)" "unprognostic (2.44e-3)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (4.04e-2)" "unprognostic (1.24e-3)" "unprognostic (6.16e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (3.65e-5)" 37.6 9.2 2.7 2.6 10.2 0.0 25.0 4.1 5.8 24.1 10.8 14.8 1.7 17.1 4.1 8.0 34.9 18.0 64.0 1.8 3.4 4.1 4.4 26.5 1.0 13.8 4.6 53.4 8.0 2.8 6.9 106.0 8.3 7.3 4.7 2.5 14.9 9.0 22.0 14.1 13.7 14.2 4.7 5.0 17.4 9.2 7.5 2.7 14.6 42.9 0.7 18.1 18.1 6.4 0.0 0.1 2.8 0.1 255.1 184.5 0.0 26.1 9.5 0.6 0.6 0.0 0.2 0.0 0.3 28.2 0.2 0.1 1.6 0.1 0.6 0.1 0.0 0.1 0.0 0.0 55.5 0.0 0.3 156.4 0.1 13.5 0.3 0.2 0.3 0.0 0.0 1.0 44.1 0.0 0.0 0.1 0.5 0.8 0.0 0.0 14.5 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 22.2 1.4 0.1 0.3 8.9 0.3 0.0 1.7 0.0 2.9 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 2.7 10.2 4.1 5.8 1.8 3.4 13.8 4.6 8.3 4.7 7.5 6.4 7.7 0.0 0.5 24.8 0.0 3.7 2.2 0.5 1.2 1.3 1.1 0.8 90.7 0.0 0.9 0.0 0.0 2.1 0.5 0.0 0.0 1.4 7.5 6.5 75.1 8.5 0.0 0.0 363.1 0.2 1.9 151.1 11.7 6.5 0.0 1.0 3.6 0.0 3.0 0.0 8.6 0.0 0.0 0.0 4.4 11.7 184.2 1.9 1.8 692.3 0.1 11.1 3.1 8.0 160.9 0.9 0.0 224.2 0.5 1.0 0.0 0.6 4.5 1.1 118.3 122.1 8.8 2.6 1.9 1.2 2.8 3.8 1.7 44.5 0.0 1.1 LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 171.0;Gastric mucus-secreting cells: 138.1;Pancreatic endocrine cells: 585.5;Paneth cells: 170.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 1237.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 1800000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" 10.0 1.2 8.3 8.5 3.6 0.1 20.3 2.8 5.9 15.4 5.4 13.6 17.8 15.6 4.7 14.5 12.0 7.4 4.2 4.1 3.5 3.2 1.7 20.9 4.1 3.8 5.9 5.7 4.7 10.9 3.0 24.8 3.6 12.2 8.4 3.7 21.3 13.5 2.0 32.1 19.7 6.9 3.5 0.8 31.8 3.3 4.3 9.5 2.3 1.7 4.1 12.2 23.1 2.9 140.5 15.7 0.1 0.1 6.9 1.3 0.3 2.6 1.8 1.3 1.7 5.4 159.5 0.1 17.3 1.8 0.4 248.5 0.2 1237.9 0.9 0.2 8.8 0.0 5.6 2.8 1.2 0.0 0.6 1.6 139.1 0.8 140.0 0.9 5.2 0.2 0.0 0.2 1.6 0.4 0.1 0.1 1.4 42.6 14.4 2.6 0.1 0.2 51.8 15.4 0.6 2.5 4.9 2.0 0.4 0.3 4.5 1.8 12.3 0.9 1.0 6.7 0.6 0.2 0.1 0.6 2.9 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.3 3.6 2.8 5.9 4.1 3.5 3.8 5.9 3.6 3.5 4.3 2.9 28.8 115.4 26.4 13.1 0.7 31.4 104.2 117.1 100.7 6.0 21.8 41.8 2.3 4.3 20.4 1.8 0.0 0.6 0.5 171.0 0.0 30.2 3.9 21.5 4.3 7.5 8.3 0.0 8.3 34.4 0.4 3.6 138.1 24.0 5.7 9.5 2.5 0.9 0.2 0.0 18.5 23.7 4.1 0.0 1.5 4.5 5.9 2.0 1.8 68.4 0.6 0.2 0.0 1.0 2.0 585.5 170.1 3.4 0.2 45.6 39.5 0.0 15.6 2.2 6.6 1.5 22.1 4.5 4.0 28.2 9.9 0.1 1.5 5.9 28.4 18.2 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMA5 ENSG00000130702 "Laminin subunit alpha 5" O15230 20 62307955-62367312 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Cytotrophoblasts: 104.4;Glandular and luminal cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 114.9;CACO-2: 159.6;EFO-21: 114.4;HaCaT: 107.2;HeLa: 118.3;TIME: 138.4" "Low region specificity" "Detected in many" "HPA058389, CAB078157" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 1800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "CAB078157: AB_2665809, HPA058389: " "unprognostic (8.01e-2)" "unprognostic (2.47e-1)" "unprognostic (1.92e-2)" "unprognostic (3.42e-3)" "unprognostic (1.17e-1)" "unprognostic (9.90e-3)" "unprognostic (4.01e-3)" "unprognostic (5.45e-2)" "unprognostic (8.99e-2)" "unprognostic (1.34e-2)" "unprognostic (5.98e-3)" "unprognostic (2.98e-3)" "unprognostic (4.04e-2)" "unprognostic (9.86e-3)" "unprognostic (2.07e-1)" "unprognostic (9.76e-2)" "unprognostic (1.33e-2)" 27.1 11.8 4.7 5.0 2.2 1.3 27.0 15.2 7.0 26.3 18.9 66.7 5.3 31.3 1.2 24.5 31.8 7.9 26.6 2.4 2.0 32.7 13.2 43.9 3.0 3.2 1.9 9.3 13.9 4.8 12.1 20.0 2.5 36.7 1.2 0.6 17.8 15.4 11.0 36.0 19.9 7.3 0.6 14.0 25.1 4.6 9.3 2.7 28.6 2.8 1.9 32.6 30.2 0.4 15.1 114.9 2.2 14.8 2.7 31.0 85.9 4.2 2.2 3.3 0.6 159.6 59.1 1.3 114.4 0.1 3.6 107.2 3.1 45.8 0.2 0.3 6.5 3.8 118.3 46.1 9.9 0.0 16.6 1.6 29.6 7.9 8.0 5.7 15.0 0.0 7.0 1.7 0.0 22.3 0.1 0.4 7.3 19.3 65.9 0.2 1.4 12.8 28.6 70.3 1.1 44.5 63.2 62.2 1.2 11.6 62.0 0.9 138.4 1.6 41.2 0.7 18.9 0.8 0.2 0.6 31.7 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 2.2 15.2 7.0 2.4 2.0 3.2 1.9 2.5 0.6 9.3 0.4 60.2 76.9 37.1 19.9 6.9 17.1 16.0 56.8 52.9 3.6 16.7 20.8 20.5 12.8 43.9 38.6 8.4 104.4 3.9 0.6 0.0 28.6 4.3 35.5 11.7 49.6 2.4 6.1 5.9 4.5 23.3 13.0 6.1 82.0 2.5 0.9 18.9 12.7 13.1 3.3 12.7 0.3 14.2 0.6 5.4 1.3 9.9 2.2 1.8 10.3 1.1 8.2 1.0 3.5 1.3 13.2 0.1 19.5 8.5 21.9 0.0 12.2 49.6 1.8 26.3 11.0 39.4 0.6 1.7 23.4 12.6 57.3 2.2 1.7 0.6 27.5 LAMB1 CLM ENSG00000091136 "Laminin subunit beta 1" P07942 7 107923799-108003213 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 185.6;Fibroblasts: 99.6;Peritubular cells: 141.8;Theca cells: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 593.0;ASC TERT1: 815.3;HSkMC: 779.6;TIME: 547.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004056, HPA004132, CAB004256" Enhanced "Secreted to extracellular matrix" NA NA 250000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "CAB004256: AB_627867, HPA004056: AB_1079226, HPA004132: AB_1079225" "unprognostic (2.39e-1)" "unprognostic (6.45e-3)" "unprognostic (2.01e-1)" "unprognostic (6.75e-2)" "unprognostic (3.45e-3)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (3.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "unprognostic (3.44e-1)" "unprognostic (5.01e-2)" "unprognostic (2.87e-2)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-1)" 141.4 21.8 1.2 26.5 1.6 0.1 74.1 0.9 1.7 46.4 23.0 87.0 29.3 78.9 3.3 25.2 44.1 53.4 53.9 2.4 0.7 81.4 14.7 104.3 9.4 0.0 0.8 29.4 48.2 12.1 11.8 154.3 0.2 18.1 40.4 0.7 24.6 29.7 20.4 39.3 67.5 73.2 0.1 42.4 49.5 11.4 1.4 19.7 43.5 40.6 5.2 53.5 31.0 0.4 94.5 148.6 77.3 3.6 593.0 815.3 291.9 103.5 182.5 68.6 72.1 306.7 166.6 0.0 127.7 200.3 90.8 41.9 24.8 143.6 49.9 0.1 24.8 4.8 52.6 87.9 364.3 0.0 2.8 779.6 49.0 175.9 193.4 409.2 450.0 2.8 17.0 0.0 126.5 29.9 0.1 0.5 42.9 54.9 103.6 0.4 51.9 0.3 238.5 96.0 24.3 142.1 75.1 100.9 68.5 180.2 37.6 1.1 547.1 179.9 44.3 60.2 133.1 0.0 0.2 0.4 89.9 0.0 301.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.9 1.7 2.4 0.7 0.0 0.8 0.2 0.1 1.4 0.4 81.8 0.0 5.6 2.9 2.2 8.9 5.2 16.7 10.8 12.1 2.0 9.5 16.3 15.7 7.6 27.6 4.2 85.5 3.5 10.5 3.9 18.0 2.0 22.6 185.6 57.8 19.2 0.0 51.6 11.2 27.1 99.6 2.6 34.6 2.5 2.9 20.7 3.5 10.1 8.4 23.7 8.0 8.2 2.8 3.8 4.7 71.1 2.4 8.8 11.2 2.0 2.1 5.2 6.0 3.2 21.6 17.0 141.8 0.4 3.6 9.5 11.6 2.9 8.6 52.6 10.2 54.4 5.5 5.1 4.7 6.7 32.6 3.2 174.7 19.2 2.1 LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.8;Leydig cells: 146.3;Peritubular cells: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 299.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 25000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" 75.2 73.2 12.8 18.2 14.2 2.6 58.2 15.1 14.9 68.0 47.7 63.1 24.6 72.7 25.5 31.9 63.8 62.2 169.1 13.1 14.5 41.3 31.7 55.1 16.9 20.0 14.8 94.4 32.7 104.7 15.4 99.0 15.4 50.4 18.0 11.7 40.3 81.0 67.5 40.9 32.5 80.2 14.1 29.8 48.4 21.4 17.3 6.7 60.2 70.0 12.8 52.2 55.9 13.5 15.7 38.7 34.4 122.0 196.3 201.5 31.1 131.9 161.8 73.8 75.7 18.3 52.0 0.2 44.4 299.0 38.3 49.3 30.0 47.6 52.3 0.1 9.5 6.9 63.4 32.1 132.5 0.3 0.3 176.9 69.4 61.6 62.1 184.3 75.9 0.0 4.1 0.1 61.4 30.3 0.1 0.3 15.1 20.7 32.0 0.2 16.6 0.5 53.5 19.1 0.2 20.4 74.9 42.9 68.3 57.5 93.4 0.9 126.9 82.2 34.9 28.5 35.4 0.1 0.4 0.4 39.1 0.3 57.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 14.2 15.1 14.9 13.1 14.5 20.0 14.8 15.4 14.1 17.3 13.5 83.7 118.6 53.5 26.1 2.4 31.2 13.9 33.6 33.0 1.7 39.4 40.5 151.8 37.1 43.6 55.2 6.2 11.3 0.9 3.6 5.9 26.4 3.5 15.4 24.4 77.8 0.0 0.4 0.2 9.4 6.4 120.1 50.4 27.2 1.3 88.9 94.9 49.9 10.4 8.4 0.4 3.1 32.6 10.1 31.1 12.3 146.3 7.5 42.7 15.9 3.5 46.7 2.1 1.0 0.6 14.1 14.9 140.7 0.5 10.2 16.4 28.6 11.2 2.6 118.3 80.8 92.3 4.3 8.6 14.2 24.4 9.4 3.8 27.6 5.6 9.3 LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.2;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 370.0;Basal respiratory cells: 447.6;Pancreatic endocrine cells: 853.8;Urothelial cells: 392.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 353.8;HaCaT: 538.2;HBEC3-KT: 1315.0;hTCEpi: 412.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 20000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" 10.9 16.0 2.6 13.1 2.9 10.7 20.7 0.9 21.3 13.2 0.5 26.2 31.5 18.0 2.6 47.2 16.4 11.9 6.8 2.9 2.1 16.3 9.3 28.4 1.2 1.5 1.5 1.1 4.2 0.1 1.7 5.8 1.6 25.9 16.6 0.2 41.5 24.1 6.8 42.1 43.7 2.3 1.7 1.0 73.2 1.0 1.9 5.8 1.2 0.3 13.2 73.1 32.6 2.8 178.4 25.8 0.0 0.4 18.1 11.7 1.0 5.1 15.4 6.0 9.1 68.9 353.8 0.1 15.1 3.7 8.9 538.2 0.1 1315.0 9.1 13.1 1.4 1.1 86.9 1.1 2.4 1.0 1.3 2.6 412.8 19.1 253.4 11.7 6.4 0.1 2.5 6.7 1.9 0.3 0.2 1.2 0.6 81.0 74.0 0.2 17.1 165.4 70.9 109.0 0.5 0.5 73.9 8.5 15.4 1.0 2.0 9.7 138.3 29.1 61.3 1.0 104.6 1.7 3.4 0.4 42.2 0.8 2.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 2.6 2.9 0.9 21.3 2.9 2.1 1.5 1.5 1.6 1.7 1.9 2.8 0.4 221.2 67.7 1.6 1.2 109.7 370.0 447.6 159.9 0.3 11.5 64.4 8.4 4.3 168.5 47.8 0.0 1.1 0.4 247.5 0.0 180.5 6.0 50.8 10.0 3.5 7.8 0.4 2.5 153.0 1.4 7.5 195.7 135.0 18.4 0.2 0.4 3.9 2.0 3.3 2.3 71.7 18.3 0.3 30.0 10.9 1.8 9.9 8.8 0.0 2.1 0.4 0.0 1.0 1.7 853.8 229.1 0.7 2.1 185.0 111.9 2.3 52.2 0.3 0.0 5.3 10.4 0.3 0.6 51.7 26.0 0.5 4.0 0.0 63.1 392.7 LAMB4 ENSG00000091128 "Laminin subunit beta 4" A4D0S4 7 108023548-108130361 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 38.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 34.9;Basal squamous epithelial cells: 41.5;Early spermatids: 12.7;Late spermatids: 11.1;Suprabasal keratinocytes: 13.8" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.8;HMC-1: 1.1" "Low region specificity" "Detected in all" "HPA020242, HPA024247" Approved "Secreted to extracellular matrix" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "HPA020242: AB_2670388, HPA024247: AB_2671496" "unprognostic (7.41e-2)" "unprognostic (1.79e-1)" "unprognostic (4.85e-2)" "unprognostic (1.77e-1)" "unprognostic (3.79e-2)" "unprognostic (6.29e-4)" "unprognostic (8.90e-3)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.27e-2)" "unprognostic (1.23e-4)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" 0.1 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 1.9 0.0 0.1 0.1 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 38.9 0.2 0.0 0.0 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 2.0 0.0 34.9 0.0 0.0 41.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.7 0.0 0.0 5.9 0.0 12.7 3.8 0.1 0.8 0.0 0.0 2.1 0.2 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 1.9 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 5.1 0.5 4.2 13.8 1.4 0.0 0.1 0.0 0.1 LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 231.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1582.4;ASC TERT1: 863.5;HSkMC: 980.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" NA NA 100000000 "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Plasma membrane" "CAB004486: AB_627870, CAB078163: AB_2665817, HPA001908: AB_1079229, HPA001909: AB_1079230" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-2)" "unprognostic (8.84e-3)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.38e-2)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-3)" "unprognostic (1.10e-3)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.85e-5)" 117.2 16.4 6.3 34.9 7.2 1.1 79.3 9.2 7.1 55.1 13.8 78.3 16.0 63.2 19.3 44.5 63.8 54.7 61.7 7.2 8.7 19.4 13.8 58.7 15.3 6.9 7.7 36.1 19.2 20.0 9.5 231.7 6.0 31.3 34.3 3.7 28.1 50.9 50.5 40.8 48.9 102.3 6.4 8.4 51.1 18.7 8.6 14.7 40.3 60.1 12.0 66.9 47.7 5.4 52.5 83.5 268.4 76.7 1582.4 863.5 405.0 374.8 373.0 147.8 87.1 249.4 58.2 18.8 168.6 180.8 87.9 127.4 51.7 99.2 112.7 0.6 52.6 0.9 71.1 91.3 248.1 16.6 8.9 980.4 52.2 177.0 138.7 262.7 261.0 0.2 0.6 55.5 182.5 22.8 0.2 17.4 109.3 96.0 15.7 13.5 226.2 9.9 237.6 137.0 17.6 50.1 98.9 0.7 95.6 459.0 21.2 43.6 486.5 179.1 70.0 168.2 95.4 21.6 0.3 12.4 148.7 12.3 177.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 7.2 9.2 7.1 7.2 8.7 6.9 7.7 6.0 6.4 8.6 5.4 81.2 35.3 21.6 32.7 8.1 31.4 46.1 44.4 35.9 3.1 7.1 17.4 57.5 27.1 21.0 36.8 4.2 101.9 0.2 1.6 1.9 59.2 5.7 32.5 58.5 80.9 1.2 0.0 69.2 23.3 69.0 187.8 8.6 78.5 2.5 53.0 26.7 19.1 18.7 1.7 50.0 2.4 18.3 10.7 20.6 6.8 120.9 4.5 33.8 106.8 6.0 2.2 1.0 35.2 2.5 44.7 2.6 62.4 11.0 59.9 0.5 12.4 14.8 0.7 72.3 73.9 102.1 17.6 36.8 17.0 16.9 72.1 2.8 74.4 3.5 25.8 LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.3" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 1531.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 574.7;CAPAN-2: 501.6;HBEC3-KT: 2492.2;hTERT-HME1: 1487.5;RPTEC TERT1: 579.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004257, HPA024638, HPA046539, CAB078165" Enhanced Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" No No 130000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" 3.5 0.1 0.2 16.2 1.9 0.1 20.9 2.6 0.6 15.1 0.2 12.1 2.6 12.3 2.1 7.7 34.9 13.0 3.0 0.2 0.2 13.8 0.7 24.9 8.0 0.0 0.1 1.0 3.3 0.0 4.2 10.9 0.1 5.4 12.9 0.1 12.9 6.1 1.7 17.5 15.0 3.3 0.0 0.9 14.9 2.8 0.1 11.3 18.5 2.3 12.3 39.3 6.3 0.2 574.7 25.4 0.0 0.7 4.9 11.9 40.2 4.3 4.7 2.1 0.7 41.4 501.6 0.0 207.9 1.4 16.4 252.4 0.1 2492.2 2.7 0.7 0.2 0.0 0.5 0.1 1.2 0.0 0.2 6.1 189.7 6.0 1487.5 2.3 32.6 0.0 0.0 0.2 2.5 1.1 0.0 0.1 4.5 206.7 35.2 0.1 1.2 0.0 579.4 147.1 30.5 0.1 14.7 0.4 0.9 14.9 2.0 2.7 3.8 2.2 30.2 15.0 7.8 0.9 0.7 0.7 4.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 2.6 0.6 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 218.0 17.8 0.0 0.2 86.3 227.1 232.7 105.3 0.0 8.2 26.2 2.3 10.0 56.8 23.9 0.0 30.7 0.4 74.4 0.0 183.4 19.6 68.9 3.6 7.8 9.0 0.0 0.4 94.0 11.7 17.2 59.7 97.4 0.0 0.0 0.0 0.0 2.5 0.0 0.3 34.1 14.2 0.0 4.9 11.8 3.4 3.1 8.8 1.0 2.6 0.0 0.0 0.0 0.3 1531.1 91.2 0.4 0.3 302.0 16.7 0.2 69.3 0.0 0.0 3.4 9.6 3.6 1.0 60.3 29.7 83.3 5.3 0.1 15.3 169.9 LAMC3 DKFZp434E202 ENSG00000050555 "Laminin subunit gamma 3" Q9Y6N6 9 131009174-131094473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 48.7" "Group enriched" "Detected in many" 4 "Leydig cells: 118.4;Peritubular cells: 364.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;EFO-21: 17.3;Hep G2: 6.1;SiHa: 6.7;U-2 OS: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022814 Enhanced "Secreted to extracellular matrix" NA NA 1100000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA022814: AB_2670960" "unprognostic (9.77e-2)" "unprognostic (1.90e-1)" "unprognostic (9.55e-3)" "unprognostic (2.09e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" "unprognostic (1.38e-2)" "unprognostic (2.28e-3)" "unprognostic (6.27e-2)" "unprognostic (1.83e-1)" "unprognostic (1.58e-1)" "unprognostic (3.38e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-1)" "unprognostic (3.34e-1)" "unprognostic (7.83e-2)" 1.5 13.5 1.3 0.3 1.8 0.0 1.5 1.3 2.4 22.3 1.9 1.6 0.4 3.3 3.5 1.7 1.1 2.7 1.2 1.4 1.2 9.2 4.9 23.3 0.0 1.4 1.3 1.7 3.5 0.9 11.6 48.7 1.2 4.2 0.1 0.0 1.4 3.8 0.3 8.6 0.3 0.3 1.2 11.3 0.5 19.0 1.7 0.2 1.2 1.1 0.0 15.0 8.2 2.0 0.0 0.5 4.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 17.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 2.2 0.0 1.5 6.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.2 2.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.4 0.1 6.7 0.0 2.6 0.4 0.0 0.7 0.0 0.0 5.3 0.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 1.3 1.8 1.3 2.4 1.4 1.2 1.4 1.3 1.2 1.2 1.7 2.0 1.5 0.0 0.0 1.0 0.0 6.8 0.0 0.0 0.0 0.0 0.4 0.4 1.3 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.1 1.9 1.6 48.5 1.7 0.0 0.0 1.7 0.0 0.8 20.7 0.0 1.1 0.0 27.8 3.6 0.1 1.5 0.0 4.1 0.2 0.0 0.0 10.2 12.6 118.4 0.5 10.6 36.5 0.1 0.0 0.0 0.0 1.0 0.1 0.0 364.1 0.0 0.2 0.0 0.2 0.0 0.0 46.0 0.1 10.0 1.0 3.5 0.0 4.4 1.0 0.8 38.1 0.0 0.1 LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1338.5" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 458.3" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 10.7;HSkMC: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001508, CAB025905" Approved "Secreted to blood" NA NA 25000000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" 58.2 0.5 0.0 24.2 0.1 0.5 6.6 0.0 0.2 4.6 0.0 0.5 0.0 2.6 0.0 0.1 0.6 0.2 3.3 0.0 0.0 8.7 1338.5 1.2 2.8 1.1 0.1 0.2 1.7 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.4 0.0 22.8 0.6 0.6 1.5 0.0 0.5 0.6 0.7 0.4 0.1 3.9 2.0 0.3 0.7 0.2 0.3 0.0 0.1 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.6 0.7 0.0 0.0 0.1 0.0 0.0 7.9 0.8 1.0 0.1 0.2 0.5 0.0 10.7 0.3 11.0 0.1 0.8 0.0 0.7 0.0 0.0 9.7 458.3 0.3 0.0 0.3 0.0 0.0 8.5 0.0 0.3 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 15.2 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 LCAT ENSG00000213398 "Lecithin-cholesterol acyltransferase" P04180 16 67939750-67944131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Hydrolase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 283.0" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 219.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 76.5;Hep G2: 62.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 29.2" HPA044767 Approved Nucleoplasm "Secreted to blood" NA NA 6470000000 6400000000 "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA044767: AB_2756312" "unprognostic (3.34e-2)" "unprognostic (3.56e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.43e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-1)" "prognostic favorable (4.21e-8)" "unprognostic (6.42e-2)" "unprognostic (4.26e-1)" "unprognostic (4.12e-1)" "unprognostic (1.50e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (9.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.90e-3)" 29.5 20.8 29.3 8.3 29.8 4.2 27.2 56.7 37.5 41.4 37.8 30.6 5.0 28.7 9.1 13.4 26.1 11.5 42.0 28.5 32.3 33.2 283.0 36.1 7.5 41.9 32.7 28.5 17.7 8.0 17.5 17.8 31.6 40.0 4.8 2.8 16.9 18.6 13.2 32.0 17.8 12.3 31.9 23.3 16.5 11.3 33.4 9.4 43.2 8.9 4.4 27.5 27.3 32.0 5.7 9.0 13.0 14.8 11.1 15.6 76.5 21.9 9.3 14.5 10.2 29.5 6.8 3.1 4.0 31.9 5.3 19.4 3.1 30.0 8.9 1.5 7.9 3.9 22.8 62.9 15.2 0.7 10.3 27.1 27.9 30.0 10.4 19.5 10.8 8.7 8.7 1.2 10.5 9.1 3.7 9.5 8.6 1.1 5.0 4.0 14.1 3.3 4.1 9.6 0.5 6.7 33.1 1.6 3.9 26.5 18.6 6.0 20.6 18.5 28.8 20.7 8.1 17.7 5.2 8.3 8.9 2.5 16.5 0.9 0.4 1.9 0.3 0.0 0.4 0.4 0.2 0.3 0.1 0.6 0.4 0.1 1.0 0.4 0.1 0.3 0.0 0.0 29.3 29.8 56.7 37.5 28.5 32.3 41.9 32.7 31.6 31.9 33.4 32.0 16.5 9.6 4.8 27.4 1.1 9.4 4.1 4.6 6.8 0.4 1.9 5.5 7.9 5.7 3.3 3.7 2.1 7.7 1.3 0.1 0.0 1.7 0.2 2.1 6.0 8.0 1.2 14.3 0.1 1.0 3.4 7.3 1.1 1.6 1.3 5.4 10.8 219.5 2.4 0.0 0.1 0.0 4.1 6.6 3.8 1.3 8.7 2.4 7.2 6.5 3.0 7.7 1.0 4.5 1.4 2.1 0.0 8.6 1.9 4.3 0.0 0.4 4.4 0.6 13.1 7.6 10.4 0.9 1.4 0.9 2.6 12.2 1.6 4.1 0.1 1.7 LCN1 "MGC71975, PMFA, TLC, TP, VEGP" ENSG00000160349 "Lipocalin 1" P31025 9 135521438-135526540 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Sensory transduction, Taste, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.8;seminal vesicle: 8.0" "Cell type enriched" "Detected in some" 8 "Basal prostatic cells: 8.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 3800000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.50e-3)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (3.99e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-4)" "unprognostic (1.22e-1)" "unprognostic (7.84e-2)" "unprognostic (9.47e-2)" "unprognostic (3.94e-8)" "unprognostic (2.07e-3)" "unprognostic (3.03e-2)" "unprognostic (5.83e-2)" 0.0 0.0 0.4 0.2 0.4 0.0 0.0 0.4 0.9 0.0 0.4 0.0 0.0 0.0 0.0 12.8 1.9 0.0 0.5 1.1 0.4 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.1 0.0 1.9 0.2 0.4 0.0 0.0 0.0 0.3 8.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.9 1.1 0.4 0.4 0.4 0.4 0.4 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 LCN10 ENSG00000187922 "Lipocalin 10" Q6JVE6 9 136738167-136743356 "Predicted secreted proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 32.3" "Cell type enriched" "Detected in single" 32 "B-cells: 6.4" "Cancer enriched" "Detected in single" 8 "thyroid cancer: 1.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "memory B-cell: 6.5;naive B-cell: 6.4" "Lineage enriched" "Detected in single" 18 "B-cells: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055919 Approved "Secreted in male reproductive system" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 57: B-cells - Immune response" "HPA055919: AB_2682969" "unprognostic (2.02e-1)" "unprognostic (1.35e-2)" "unprognostic (2.62e-1)" "unprognostic (1.89e-1)" "unprognostic (5.85e-2)" "unprognostic (6.54e-3)" "unprognostic (2.22e-4)" "unprognostic (4.54e-2)" "unprognostic (3.97e-1)" "unprognostic (1.31e-1)" "unprognostic (4.14e-3)" "unprognostic (2.96e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (2.52e-1)" "unprognostic (8.32e-2)" "unprognostic (3.86e-1)" 3.5 0.1 1.4 1.0 1.3 0.8 2.8 1.2 2.3 6.1 1.2 1.7 0.1 7.7 32.3 1.2 7.8 0.4 8.2 1.3 1.2 0.1 0.1 0.9 1.3 1.3 1.3 2.1 1.0 0.3 0.1 0.0 1.3 2.7 0.7 0.0 1.6 1.0 0.8 0.7 2.7 3.1 1.2 1.6 2.2 1.2 1.6 0.3 2.1 2.0 1.1 3.2 2.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.4 1.3 1.2 2.3 1.3 1.2 1.3 1.3 1.3 1.2 1.6 1.3 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 LCN12 MGC48935 ENSG00000184925 "Lipocalin 12" Q6JVE5 9 136949551-136955497 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "epididymis: 79.5" "Cell type enhanced" "Detected in many" "Astrocytes: 19.6;Collecting duct cells: 49.7;Distal tubular cells: 19.6;Endometrial ciliated cells: 29.8;Glandular and luminal cells: 57.2;Muller glia cells: 27.1" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 44.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Endometrium - Transcription" "unprognostic (7.27e-3)" "unprognostic (5.72e-3)" "unprognostic (2.45e-2)" "unprognostic (7.14e-2)" "unprognostic (4.53e-4)" "unprognostic (9.33e-3)" "unprognostic (1.97e-3)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (3.03e-1)" "unprognostic (7.33e-3)" "unprognostic (2.18e-1)" "unprognostic (5.73e-2)" "unprognostic (5.21e-3)" "unprognostic (3.06e-1)" "unprognostic (5.00e-2)" "unprognostic (7.91e-4)" 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.8 2.9 0.5 0.1 0.3 0.2 79.5 0.0 3.4 0.0 0.1 0.3 0.3 0.6 1.2 0.0 0.0 1.0 0.4 0.0 0.5 0.6 0.6 0.0 0.2 0.0 0.1 0.1 0.1 1.9 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.1 0.4 0.2 6.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.2 0.8 0.3 0.3 1.0 0.4 0.2 0.4 0.4 0.3 0.1 0.0 2.2 19.6 0.3 0.0 0.4 0.9 0.0 0.3 2.8 1.3 8.0 2.8 2.3 49.7 2.1 0.1 1.7 2.9 19.6 1.2 1.5 29.8 4.3 0.4 16.4 0.0 1.0 1.2 0.0 0.8 0.0 57.2 0.0 6.7 0.0 13.8 0.2 0.0 0.7 4.0 4.1 0.6 0.0 1.0 14.9 0.5 0.0 3.7 0.0 27.1 2.1 1.0 0.2 0.5 1.2 10.9 0.5 0.7 4.4 6.1 1.3 0.9 0.0 0.0 0.2 1.1 0.5 0.0 0.0 0.3 0.5 7.8 5.7 0.3 LCN15 "PRO6093, UNQ2541" ENSG00000177984 "Lipocalin 15" Q6UWW0 9 136759634-136766255 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.9;seminal vesicle: 3.3" "Cell type enriched" "Detected in some" 4 "Enteroendocrine cells: 391.5" "Cancer enriched" "Detected in some" 19 "colorectal cancer: 23.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "Hep G2: 17.7" "Low region specificity" "Detected in all" HPA060584 Enhanced "Secreted in other tissues" NA NA "Cluster 45: Intestine - Brush border" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA060584: AB_2684327" "unprognostic (5.24e-1)" "unprognostic (2.61e-1)" "unprognostic (2.14e-1)" "unprognostic (3.67e-1)" "unprognostic (3.45e-2)" "unprognostic (3.28e-2)" "unprognostic (2.39e-1)" "unprognostic (1.83e-1)" 0.1 0.0 2.3 0.0 2.3 0.0 0.1 2.3 2.7 0.0 2.3 3.0 11.9 0.0 1.4 0.0 0.0 0.0 1.3 2.3 2.3 0.0 0.0 0.0 0.0 2.3 2.3 0.0 0.0 0.0 0.0 0.1 2.3 0.3 1.9 0.0 0.0 3.3 0.6 0.0 3.7 0.0 2.3 0.1 0.0 0.1 2.3 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.3 2.3 2.7 2.3 2.3 2.3 2.3 2.3 2.3 2.3 2.3 1.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.2 0.0 0.6 391.5 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.3 96.9 24.4 0.3 0.4 2.8 0.0 0.1 1.8 0.0 0.0 0.0 0.0 1.0 0.8 0.0 14.7 0.0 0.0 0.2 5.5 0.1 0.0 0.9 0.0 0.3 0.1 0.1 0.4 0.0 0.1 0.0 0.1 0.1 0.9 0.4 LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2768.7;gallbladder: 2223.2;salivary gland: 1308.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4054.2;Club cells: 5757.0;Ductal cells: 6457.0;Pancreatic endocrine cells: 5424.3;Respiratory ciliated cells: 3161.5;Urothelial cells: 7112.9" "Cancer enhanced" "Detected in many" "stomach cancer: 944.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 88 "basophil: 9.8;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 83 "granulocytes: 11.9;monocytes: 4.7" "Group enriched" "Detected in many" 11 "CAPAN-2: 3623.8;EFO-21: 1450.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "cerebellum: 149.7;spinal cord: 102.4" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 297000000 590000000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: AB_1852758" "prognostic favorable (9.61e-4)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (7.38e-3)" "unprognostic (1.01e-2)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-3)" "unprognostic (6.15e-2)" "unprognostic (2.37e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-2)" 4.9 3.6 0.0 125.5 0.1 2768.7 22.0 0.1 0.5 810.5 2.0 249.1 34.4 14.2 20.5 677.6 52.6 2223.2 3.1 0.0 0.1 31.6 67.8 76.1 1.1 0.3 0.1 1.1 74.8 7.3 21.2 2.6 0.3 74.5 131.0 0.0 1308.3 13.5 1.2 28.1 157.3 11.9 0.1 82.0 363.9 0.5 0.1 14.2 27.1 0.3 199.1 669.9 480.7 0.1 117.7 35.1 0.0 4.5 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 3623.8 0.2 1450.9 0.0 3.7 236.4 0.0 6.9 0.1 5.3 0.0 30.4 0.0 0.8 0.2 0.0 1.1 0.1 230.4 0.0 12.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 1.9 80.9 0.2 0.2 0.3 0.3 1.0 20.1 0.1 0.1 2.0 65.3 1.0 0.0 8.4 1.8 0.0 2.9 16.9 0.0 2.9 0.6 4.6 4.7 0.2 0.6 2.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 4.7 0.0 0.0 12.1 0.0 0.1 0.1 0.5 0.0 0.1 0.3 0.1 0.3 0.1 0.1 0.1 0.2 0.0 20.8 0.0 15.9 0.3 376.6 4054.2 1.8 0.0 38.1 29.3 0.2 1328.2 5757.0 138.0 0.0 0.8 1.2 315.6 0.0 6457.0 2.0 25.6 4.3 11.5 57.9 11.2 0.0 1837.0 0.3 12.2 237.0 52.3 13.4 0.0 2.2 43.2 0.6 0.0 0.0 264.3 956.2 2.7 0.0 15.8 3.4 34.9 0.0 0.0 60.3 0.0 1.0 0.0 0.0 5424.3 183.4 0.0 1.4 420.6 509.8 1.6 3161.5 0.0 0.0 0.0 337.7 0.0 0.3 51.1 0.0 0.3 7.7 0.0 475.5 7112.9 LCN6 ENSG00000267206 "Lipocalin 6" P62502 9 136744017-136748525 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 60 "epididymis: 1581.7" "Group enriched" "Detected in some" 4 "Adipocytes: 20.2;Endothelial cells: 80.6" "Cancer enriched" "Detected in some" 10 "thyroid cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NB-4: 3.3;REH: 10.7" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.05e-2)" "unprognostic (1.01e-3)" "unprognostic (1.12e-1)" "unprognostic (5.88e-2)" "unprognostic (3.23e-1)" "unprognostic (1.26e-1)" "unprognostic (3.83e-4)" "unprognostic (3.41e-2)" "unprognostic (7.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.89e-3)" "unprognostic (1.78e-1)" "unprognostic (5.55e-2)" "unprognostic (2.96e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-1)" 10.3 0.3 2.2 1.3 1.9 4.4 9.8 1.7 2.8 11.7 1.7 5.1 0.4 19.1 1581.7 3.3 12.7 2.0 26.3 1.8 1.9 0.9 0.3 3.4 0.9 1.9 2.1 5.6 3.1 0.9 0.5 0.0 2.0 7.6 0.8 0.0 4.5 4.3 2.8 2.2 7.6 5.3 1.8 3.2 7.3 3.9 2.7 0.4 5.2 6.5 0.4 8.3 6.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 1.7 2.8 1.8 1.9 1.9 2.1 2.0 1.8 2.7 1.9 20.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 80.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 5.6 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.4 0.0 0.0 0.0 0.1 6.6 0.1 1.6 0.4 0.5 0.0 0.0 0.0 5.3 0.0 0.0 1.5 LCN8 LCN5 ENSG00000204001 "Lipocalin 8" Q6JVE9 9 136754386-136758543 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 99 "epididymis: 83.7" "Group enriched" "Detected in some" 11 "B-cells: 17.9;Plasma cells: 5.6" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 60 "memory B-cell: 4.1;naive B-cell: 8.1" "Lineage enriched" "Detected in single" 79 "B-cells: 8.1" "Cell line enriched" "Detected in single" 6 "REH: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (6.71e-2)" "unprognostic (2.11e-2)" "unprognostic (2.92e-1)" "unprognostic (2.89e-1)" "unprognostic (2.00e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LCN9 ENSG00000148386 "Lipocalin 9" Q8WX39 9 135663322-135666422 "Predicted secreted proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "BEWO: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060941 Enhanced "Secreted in male reproductive system" NA NA "Cluster 28: BEWO - Transcription regulation" "HPA060941: AB_2732654" "unprognostic (7.64e-4)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.2 0.2 0.2 0.2 0.5 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LDLRAD2 ENSG00000187942 "Low density lipoprotein receptor class A domain containing 2" Q5SZI1 1 21812265-21825225 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Granulosa cells: 4.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 1.2;THP-1: 1.0;TIME: 2.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "basal ganglia: 4.0;midbrain: 5.9" HPA030478 Approved "Secreted - unknown location" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "HPA030478: AB_10601541" "unprognostic (4.16e-2)" "unprognostic (1.22e-1)" "unprognostic (4.13e-2)" "unprognostic (4.21e-2)" "unprognostic (1.78e-1)" "unprognostic (6.22e-3)" "unprognostic (1.35e-2)" "unprognostic (4.85e-2)" "unprognostic (7.52e-2)" "unprognostic (3.80e-2)" "unprognostic (5.34e-2)" "unprognostic (5.38e-2)" "unprognostic (1.04e-3)" "unprognostic (7.39e-3)" "unprognostic (3.14e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" 3.7 2.8 0.4 0.8 0.3 1.0 3.0 0.2 0.1 2.7 0.4 4.3 1.6 3.5 0.0 1.7 2.7 0.5 6.8 0.7 1.1 2.2 0.7 1.6 0.7 2.4 3.3 1.1 2.0 0.0 1.5 0.1 1.7 3.7 0.1 0.0 7.2 0.0 1.2 1.3 2.4 0.1 1.7 2.7 3.7 1.4 1.4 0.0 2.2 0.0 0.3 3.9 2.4 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.5 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.1 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 1.0 2.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.3 0.2 0.1 0.7 1.1 2.4 3.3 1.7 1.7 1.4 0.3 2.2 0.0 0.6 0.0 0.6 0.5 0.1 0.4 0.6 0.0 0.1 0.1 0.7 0.0 0.2 1.8 0.0 0.2 0.3 0.0 0.0 0.2 1.7 0.3 1.2 1.6 0.0 1.3 0.2 0.0 0.6 1.3 0.0 0.9 0.0 4.9 0.7 0.2 0.3 0.0 0.1 0.0 0.0 0.3 0.2 0.4 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.3 0.5 0.0 0.0 0.8 0.0 0.0 1.2 0.7 0.6 1.2 0.1 0.4 0.3 0.4 0.4 0.0 0.0 LEAP2 LEAP-2 ENSG00000164406 "Liver enriched antimicrobial peptide 2" Q969E1 5 132873444-132875046 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 532.0" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 1650.6" "Cancer enriched" "Detected in many" 17 "liver cancer: 40.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 3.4;Hep G2: 4.7;U-266/84: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 790000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (2.14e-2)" "unprognostic (8.78e-2)" "unprognostic (4.75e-1)" "unprognostic (2.16e-1)" "unprognostic (2.82e-1)" "unprognostic (1.06e-2)" "unprognostic (2.78e-3)" "unprognostic (6.53e-2)" "unprognostic (3.86e-2)" "unprognostic (1.62e-1)" "unprognostic (7.08e-3)" "unprognostic (2.91e-2)" "unprognostic (1.02e-1)" "unprognostic (2.39e-1)" "unprognostic (3.97e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.68e-4)" 0.9 0.9 0.9 0.3 0.8 0.5 1.0 2.3 1.2 1.3 0.4 1.7 12.3 0.8 0.2 1.3 1.2 4.5 1.2 0.8 0.8 11.9 532.0 1.1 0.5 0.8 0.7 1.2 1.9 0.7 1.1 0.2 1.0 2.4 1.6 1.0 1.3 0.2 1.4 1.4 23.4 0.1 0.6 2.2 2.0 1.1 0.8 0.3 1.9 0.5 0.5 7.8 1.6 1.8 0.1 0.7 0.4 1.5 0.6 0.4 0.4 0.1 0.1 0.4 0.6 3.4 0.5 0.2 0.1 0.1 0.4 0.7 1.4 0.6 0.0 1.2 1.0 0.3 1.2 4.7 0.1 0.5 0.2 0.1 0.5 0.0 0.1 0.3 0.1 1.1 0.5 0.4 0.0 0.3 0.8 0.6 1.1 1.1 0.5 0.0 0.2 1.1 0.0 0.2 0.5 0.3 0.3 0.7 0.5 0.4 0.8 0.4 0.0 0.2 0.3 0.6 0.1 1.1 3.8 1.1 0.0 0.7 0.2 1.3 0.7 0.3 0.6 0.4 0.8 1.0 0.6 0.7 0.6 0.8 1.0 0.8 1.7 1.0 0.3 0.8 1.1 0.3 0.9 0.8 2.3 1.2 0.8 0.8 0.8 0.7 1.0 0.6 0.8 1.8 2.5 0.0 2.6 1.3 7.9 10.1 10.8 4.1 2.8 17.1 4.9 2.8 1.9 64.3 2.6 0.0 33.3 3.3 7.6 39.2 9.8 2.9 6.2 4.8 3.8 5.2 4.8 9.3 1.1 9.8 7.9 5.8 1.5 10.3 7.0 6.7 14.3 1650.6 1.4 13.5 1.4 12.1 0.0 17.3 14.1 0.5 1.5 4.2 5.4 1.0 2.2 5.2 13.4 2.0 1.8 2.9 30.9 1.9 3.1 14.0 279.9 51.8 1.7 25.2 0.0 13.5 4.8 7.0 2.9 1.4 7.7 7.3 6.2 4.1 8.0 10.2 LECT2 "chm-II, chm2" ENSG00000145826 "Leukocyte cell derived chemotaxin 2" O14960 5 135922279-135954983 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 477.9" "Group enriched" "Detected in some" 15 "Early spermatids: 147.7;Hepatocytes: 100.7;Late spermatids: 55.8" "Cancer enriched" "Detected in single" 216 "liver cancer: 35.1" "Region enhanced" "Detected in some" "cerebellum: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043883, HPA058246" Enhanced Supported Vesicles,Cytosol "Secreted to blood" NA NA 26500000 5300000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Vesicles "HPA043883: AB_2678714, HPA058246: " "prognostic favorable (4.16e-5)" "unprognostic (2.57e-2)" "unprognostic (3.52e-1)" 0.2 0.5 0.4 0.4 0.8 2.4 0.4 6.3 2.8 0.1 0.0 0.2 0.5 0.3 0.8 0.4 0.1 0.4 0.1 0.9 0.0 0.6 477.9 0.3 0.9 0.0 0.0 0.3 0.1 0.2 0.0 0.2 0.1 0.4 0.2 3.1 0.7 0.2 2.1 1.4 0.9 0.1 0.0 0.9 0.3 8.8 0.0 0.2 0.4 0.0 0.2 0.1 0.0 1.1 0.3 0.4 0.5 0.7 0.2 0.4 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.8 0.6 0.3 0.3 0.5 0.0 0.2 0.0 0.3 1.0 0.7 0.7 1.3 0.3 1.0 0.1 0.2 0.1 0.3 0.3 0.6 0.1 0.8 0.2 0.3 0.6 0.0 0.4 0.4 0.5 0.3 0.6 0.5 0.5 0.2 0.2 0.9 0.3 0.6 0.0 0.2 0.0 0.9 0.1 0.5 0.8 0.3 0.4 0.4 0.1 1.1 0.5 0.3 0.3 0.9 0.8 0.6 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.8 6.3 2.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 147.7 0.0 0.1 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 100.7 0.0 0.0 0.1 0.0 0.0 2.9 0.0 55.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 LEFTY1 "LEFTB, LEFTYB" ENSG00000243709 "Left-right determination factor 1" O75610 1 225886282-225911382 "Metabolic proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "intestine: 68.3;pancreas: 96.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 201.5;Glandular and luminal cells: 175.0;Intestinal goblet cells: 86.1;Paneth cells: 228.9;Undifferentiated cells: 301.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 44.8;endometrial cancer: 36.2;pancreatic cancer: 13.8;testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 51 "basophil: 17.0" "Lineage enriched" "Detected in single" 51 "granulocytes: 17.0" "Cell line enriched" "Detected in some" 6 "NTERA-2: 50.2" "HPA047883, HPA056210" Approved "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (2.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.26e-2)" "unprognostic (1.18e-2)" "unprognostic (1.83e-2)" "unprognostic (3.50e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (7.76e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (2.48e-6)" "unprognostic (2.78e-2)" "unprognostic (1.12e-1)" "unprognostic (2.01e-1)" "unprognostic (2.61e-2)" 0.3 0.2 2.1 7.8 2.1 0.0 0.4 1.8 2.7 1.4 1.3 68.3 0.2 0.5 6.9 0.1 0.6 0.0 0.4 2.1 1.9 1.7 0.9 0.3 0.0 1.6 1.7 4.1 96.9 0.0 1.0 0.2 1.7 0.9 32.4 0.8 1.5 3.3 0.4 0.2 2.9 0.8 1.6 0.3 1.4 0.8 1.9 0.0 0.1 0.1 0.1 1.5 0.2 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.3 0.0 0.0 0.0 4.5 0.1 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.2 0.0 0.0 0.0 5.4 0.6 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 2.1 2.1 1.8 2.7 2.1 1.9 1.6 1.7 1.7 1.6 1.9 1.9 0.2 0.0 0.0 0.7 1.0 0.4 1.6 0.0 0.0 1.8 0.2 0.3 0.1 14.3 0.0 0.0 0.0 0.0 0.0 51.7 1.9 20.1 1.8 201.5 9.9 0.3 31.5 0.0 2.3 29.6 0.1 1.6 0.0 175.0 0.0 1.6 0.0 0.2 0.0 0.0 2.3 86.1 0.0 0.0 0.0 3.9 1.5 2.1 0.0 0.0 0.0 0.9 0.0 1.5 0.2 0.5 228.9 1.9 0.0 0.8 0.7 6.0 0.0 1.4 0.0 0.0 0.6 2.5 4.2 0.0 0.0 0.0 1.0 1.3 301.0 1.3 LEFTY2 "EBAF, LEFTA, LEFTYA, TGFB4" ENSG00000143768 "Left-right determination factor 2" O00292 1 225936598-225941383 "Disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 74.5;endometrium 1: 170.0" "Cell type enhanced" "Detected in some" "Early spermatids: 17.4;Endometrial stromal cells: 30.8;Granulosa cells: 43.6;Late spermatids: 34.6;Leydig cells: 18.0;Peritubular cells: 12.0" "Cancer enriched" "Detected in many" 8 "testis cancer: 41.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 10.6;NTERA-2: 44.4;RPMI-8226: 50.9;SuSa: 25.5" "CAB025801, HPA047883, HPA056210" Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "CAB025801: , HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (3.78e-2)" "unprognostic (4.10e-3)" "unprognostic (5.79e-3)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (4.87e-2)" "unprognostic (9.75e-4)" "unprognostic (2.91e-1)" "unprognostic (3.84e-1)" "unprognostic (7.98e-2)" "unprognostic (9.14e-3)" "unprognostic (1.15e-1)" "unprognostic (4.69e-2)" "unprognostic (1.90e-4)" "unprognostic (1.64e-3)" 1.8 1.4 0.2 1.1 0.3 0.0 0.7 0.3 0.3 74.5 15.9 1.2 0.3 170.0 12.1 0.1 3.6 0.4 2.6 0.7 0.2 0.4 0.0 2.4 0.2 0.2 0.3 37.8 0.3 0.0 16.0 3.5 0.2 1.5 0.2 0.9 0.1 12.4 0.7 0.3 0.4 36.9 0.2 0.7 0.3 4.5 0.8 0.2 0.1 0.8 0.0 0.5 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 44.4 0.0 0.0 0.0 0.0 50.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 2.6 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.7 0.2 0.2 0.3 0.2 0.2 0.8 0.3 0.6 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.4 17.4 2.2 30.8 0.6 0.0 0.0 0.0 0.0 0.6 1.4 0.0 0.7 0.0 43.6 0.4 0.0 0.5 0.0 0.1 0.2 0.0 0.0 0.2 34.6 18.0 0.3 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 12.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 1.7 6.7 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.1 LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 307.5;breast: 90.1" "Group enriched" "Detected in some" 44 "Extravillous trophoblasts: 124.2;Syncytiotrophoblasts: 432.2" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB010490 Approved "Secreted to blood" NA NA 17000000 19000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010490: AB_2296951" "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" 307.5 0.8 0.1 5.0 0.1 0.1 90.1 0.5 0.3 0.1 0.1 2.0 0.1 0.0 0.0 0.2 0.1 1.2 1.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 2.4 0.0 0.0 4.6 0.1 0.0 0.4 0.0 1.1 0.0 0.7 3.9 1.2 0.1 0.0 0.2 0.5 0.2 0.1 0.3 0.2 1.2 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.8 0.1 0.6 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 124.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.1 432.2 0.1 0.1 0.0 0.1 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1194.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4097.0;Paneth cells: 3445.9;Proximal enterocytes: 4397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 651.4;intermediate monocyte: 544.6;myeloid DC: 397.8;non-classical monocyte: 441.2;T-reg: 251.9" "Group enriched" "Detected in all" 13 "dendritic cells: 397.8;monocytes: 651.4;T-cells: 251.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 1169.3;CAPAN-2: 968.0;OE19: 1613.0;SK-MEL-30: 2329.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1900000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" 404.5 72.0 111.4 219.8 111.8 346.9 323.1 110.7 148.1 331.4 104.3 1194.1 691.9 162.3 53.8 437.8 223.1 273.0 246.2 110.3 109.4 120.0 27.3 356.1 84.5 118.6 111.9 251.4 79.9 19.8 60.6 141.2 108.6 143.1 875.4 68.3 358.6 177.4 78.6 473.1 853.4 158.8 110.4 61.9 340.7 63.5 125.2 53.0 72.3 105.6 114.1 300.8 273.5 114.0 298.6 96.5 3.3 2.5 581.2 1169.3 344.9 226.7 496.2 64.0 113.2 225.4 968.0 0.7 121.3 272.8 114.6 289.0 6.1 245.4 37.5 357.1 4.4 1.0 104.7 103.8 446.8 1.0 1.1 363.4 375.2 73.9 152.8 145.1 101.5 0.7 1.4 283.1 148.8 218.5 1.3 74.4 5.6 1613.0 271.1 0.7 11.3 22.4 604.8 434.2 7.8 22.6 529.0 0.9 2329.1 16.2 242.8 31.4 180.5 297.8 41.5 112.0 4.4 154.0 535.6 2.8 426.8 18.6 31.8 18.5 651.4 32.4 15.7 544.6 99.7 11.5 58.4 44.2 397.8 4.7 2.5 8.3 28.7 24.2 441.2 9.6 251.9 449.6 111.4 111.8 110.7 148.1 110.3 109.4 118.6 111.9 108.6 110.4 125.2 114.0 1157.4 721.1 359.8 33.3 42.0 631.3 624.1 1278.9 241.9 2.9 307.3 478.7 218.2 258.7 1463.3 119.5 0.0 766.1 38.8 4097.0 673.1 605.9 21.7 636.2 742.7 397.8 173.4 578.1 0.2 1057.8 1051.7 666.3 281.4 846.8 580.5 6.3 64.6 2.3 1137.4 1.7 0.5 1733.8 1778.1 287.8 844.6 44.4 555.7 651.2 848.4 14.0 639.1 300.1 9.2 2.0 0.3 1289.6 3445.9 384.0 77.4 708.4 4397.2 81.3 1506.5 14.7 144.7 220.2 521.0 11.5 6.6 524.8 797.6 483.8 119.5 2.9 1880.1 1139.7 LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 629.8;Paneth cells: 584.1;Proximal enterocytes: 931.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 862.9;SK-BR-3: 2270.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" NA NA 7100000000 "Cluster 32: T-cells - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000410: , HPA000554: AB_1079246" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.63e-3)" "unprognostic (1.62e-2)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (1.57e-2)" "unprognostic (4.55e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (1.58e-1)" "unprognostic (1.65e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" 192.8 218.6 51.2 75.0 91.4 48.6 109.5 95.6 62.3 188.8 159.8 210.8 312.9 121.4 45.2 114.2 155.6 240.8 311.4 46.6 81.4 103.1 68.5 182.8 52.7 145.6 88.3 155.6 79.1 107.8 134.9 147.0 116.8 114.3 92.6 10.0 498.7 154.2 20.0 54.0 260.9 80.2 104.3 76.8 315.6 70.1 89.8 48.8 102.0 20.4 25.3 125.0 119.0 152.5 499.0 255.3 7.2 11.2 157.3 181.4 147.9 55.7 49.0 371.3 725.7 107.5 862.9 2.8 372.7 33.5 361.7 200.1 53.6 203.7 11.5 1.2 319.0 33.8 206.0 481.0 387.7 0.4 31.6 305.8 111.5 197.5 12.6 83.8 9.9 68.7 3.4 1.5 87.7 62.8 151.2 6.0 13.0 163.7 170.7 100.1 209.9 4.8 155.5 352.6 235.1 267.4 52.7 2270.3 754.5 14.0 57.5 16.1 16.3 245.5 169.8 7.1 225.8 0.8 2.2 3.7 332.1 96.8 263.7 0.8 17.7 4.9 12.0 27.2 25.0 4.7 43.3 17.9 7.6 2.4 68.4 33.0 1.2 9.4 14.7 0.6 26.0 25.1 51.2 91.4 95.6 62.3 46.6 81.4 145.6 88.3 116.8 104.3 89.8 152.5 88.0 189.1 144.3 9.8 5.6 31.1 146.8 462.5 60.3 37.2 60.5 43.1 180.7 127.2 306.2 139.8 6.2 179.1 3.4 629.8 17.6 275.0 7.2 77.4 118.7 26.8 168.2 4.4 0.3 136.5 336.0 284.6 257.9 126.9 13.3 316.5 46.8 45.8 88.3 74.0 5.3 328.7 309.3 36.8 23.7 37.1 282.7 36.0 81.8 8.4 27.9 80.8 2.1 11.6 33.9 132.4 584.1 266.3 3.5 72.4 931.4 49.2 123.9 24.3 177.5 80.5 119.6 4.5 2.1 83.8 27.3 108.9 15.4 228.3 400.5 128.2 LGALS9 LGALS9A ENSG00000168961 "Galectin 9" O00182 17 27629798-27649560 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 99.1;stomach 1: 87.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 181.1;Gastric mucus-secreting cells: 174.8;Hofbauer cells: 298.2;Intestinal goblet cells: 183.5;Kupffer cells: 254.2;Paneth cells: 181.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 40.2;HMC-1: 124.9;MOLT-4: 44.8;REH: 48.4;THP-1: 83.2;U-937: 92.1" "HPA046876, HPA047218" Approved Approved Cytosol "Secreted to blood" NA NA 448000 "Cluster 7: Monocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (2.62e-2)" "prognostic favorable (2.35e-5)" "unprognostic (1.16e-2)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (2.46e-3)" "unprognostic (1.58e-2)" "unprognostic (8.60e-2)" "unprognostic (4.79e-1)" "unprognostic (1.80e-1)" "unprognostic (8.13e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (4.76e-2)" "unprognostic (3.02e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-3)" 20.7 6.4 12.6 46.0 13.0 68.5 9.5 13.8 20.8 25.6 14.3 99.1 46.3 12.8 3.0 14.5 28.4 38.2 8.7 12.8 13.4 2.4 11.6 34.2 60.9 21.7 15.2 5.3 5.2 2.8 1.2 16.8 16.5 3.7 89.2 1.0 21.2 7.9 3.8 4.2 41.8 19.4 17.3 50.7 87.5 3.8 17.0 29.1 4.1 4.1 38.9 39.6 1.9 20.1 2.0 0.7 0.6 0.3 0.1 0.2 1.6 0.4 1.3 8.9 29.6 0.1 12.6 1.5 14.2 1.1 1.5 4.1 0.3 0.1 0.5 9.4 0.9 14.9 0.9 0.0 1.0 40.2 124.9 0.3 0.0 0.4 0.0 0.5 16.5 13.6 0.6 0.5 0.0 0.1 44.8 15.0 0.4 28.4 0.0 48.4 0.0 3.6 5.9 1.0 0.3 0.8 0.0 4.4 0.2 0.9 0.2 83.2 3.1 0.0 0.3 0.1 0.2 0.1 0.1 0.3 0.2 92.1 0.2 32.6 116.2 78.2 5.6 214.9 2.6 32.3 15.6 5.9 165.5 41.7 9.6 4.0 41.7 22.0 217.4 28.5 40.3 75.1 12.6 13.0 13.8 20.8 12.8 13.4 21.7 15.2 16.5 17.3 17.0 20.1 32.2 9.6 6.3 2.0 42.2 3.2 7.7 32.9 18.8 0.2 10.5 13.2 1.7 20.0 40.5 7.3 0.0 2.3 19.0 181.1 3.9 124.1 1.5 11.4 11.6 43.5 40.5 64.3 0.4 126.9 3.1 7.4 174.8 12.9 31.1 11.2 26.0 2.2 298.2 0.0 0.6 183.5 26.4 254.2 85.4 2.2 4.4 154.1 1.8 25.3 150.7 0.2 41.2 3.5 0.9 146.0 181.6 3.0 3.5 4.4 20.6 1.4 15.4 0.6 19.7 1.6 6.2 0.1 0.7 8.8 1.7 3.7 19.6 86.2 126.7 31.1 LGI1 "EPITEMPIN, EPT, ETL1, IB1099" ENSG00000108231 "Leucine rich glioma inactivated 1" O95970 10 93757840-93806272 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 39.7;choroid plexus: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 242.9;Excitatory neurons: 57.1;Inhibitory neurons: 74.7;Oligodendrocyte precursor cells: 28.6" "Group enriched" "Detected in some" 7 "glioma: 1.8;testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.4;CACO-2: 2.0;NTERA-2: 6.1;SuSa: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (1.26e-1)" "unprognostic (4.68e-2)" "unprognostic (2.45e-2)" "unprognostic (1.01e-1)" "unprognostic (8.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.24e-3)" "unprognostic (1.85e-1)" "unprognostic (4.07e-3)" "unprognostic (8.71e-2)" "unprognostic (2.21e-1)" "unprognostic (5.93e-2)" "unprognostic (4.65e-1)" 0.5 1.8 26.8 0.1 31.5 0.0 0.2 23.8 39.7 0.1 44.7 4.0 0.5 0.1 0.0 4.3 0.1 1.0 0.5 29.2 22.6 0.0 2.7 0.0 0.0 29.9 24.2 0.0 0.2 0.0 7.6 0.0 32.9 0.7 2.6 0.4 0.1 0.5 5.9 0.3 1.5 0.6 23.7 0.0 1.8 0.4 26.7 0.0 0.2 3.6 0.1 0.9 0.3 25.2 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 31.5 23.8 39.7 29.2 22.6 29.9 24.2 32.9 23.7 26.7 25.2 0.2 0.0 0.0 242.9 0.0 0.3 0.4 0.0 0.0 0.5 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.4 0.0 0.0 57.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 74.7 0.0 0.0 0.0 0.4 1.6 1.5 0.0 0.0 10.3 0.0 0.1 0.0 28.6 3.9 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.5 0.6 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.2 LGI2 "FLJ10675, KIAA1916" ENSG00000153012 "Leucine rich repeat LGI family member 2" Q8N0V4 4 24998847-25030946 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "parathyroid gland: 127.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Inhibitory neurons: 33.3;Oligodendrocyte precursor cells: 10.1;Skeletal myocytes: 8.6;Smooth muscle cells: 8.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 28.2;HAP1: 5.2;RPMI-8226: 13.3;SCLC-21H: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017140 Approved Uncertain Centrosome "Secreted to blood" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Centrosome "HPA017140: AB_1852833" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (4.31e-2)" "unprognostic (1.20e-5)" "unprognostic (3.99e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-2)" "unprognostic (8.54e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (3.47e-2)" "unprognostic (1.62e-1)" "unprognostic (9.38e-5)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (2.06e-4)" "unprognostic (5.03e-3)" 3.4 1.6 2.7 7.5 3.5 0.0 0.8 5.7 4.1 1.5 1.0 3.1 0.7 6.7 2.7 1.4 7.8 7.1 3.3 1.9 9.2 4.3 0.3 1.0 2.9 12.0 13.1 2.1 1.7 127.8 0.3 3.9 6.7 0.5 1.6 2.3 0.3 1.2 0.2 0.3 1.8 13.6 4.0 0.9 1.4 0.7 4.2 2.3 1.1 0.4 8.4 3.0 0.7 3.3 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.8 0.0 0.2 0.0 5.2 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.6 0.0 1.0 0.0 1.2 13.3 0.5 0.0 18.2 0.0 0.0 0.0 0.0 2.9 0.0 0.4 0.0 0.3 2.0 0.0 0.8 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.5 5.7 4.1 1.9 9.2 12.0 13.1 6.7 4.0 4.2 3.3 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 0.0 3.7 0.0 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 2.0 2.1 0.0 0.0 3.0 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.7 0.0 4.8 1.7 33.3 0.0 0.0 0.6 0.5 0.1 0.6 1.0 0.0 2.8 0.0 0.5 0.0 10.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 8.6 8.5 0.0 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.1 LGI3 ENSG00000168481 "Leucine rich repeat LGI family member 3" Q8N145 8 22146830-22157084 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 112.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 22.2;Excitatory neurons: 17.7;Inhibitory neurons: 23.7;Melanocytes: 40.9;Oligodendrocytes: 58.4" "Group enriched" "Detected in many" 5 "glioma: 4.7;melanoma: 14.3;thyroid cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;SCLC-21H: 1.6;SK-MEL-30: 1.6;WM-115: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024826 Approved Cytosol "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA024826: AB_10601131" "unprognostic (4.41e-2)" "unprognostic (1.78e-1)" "unprognostic (3.28e-1)" "unprognostic (8.11e-3)" "unprognostic (1.14e-1)" "unprognostic (7.45e-2)" "unprognostic (3.38e-1)" "unprognostic (2.43e-2)" "unprognostic (9.64e-2)" "unprognostic (1.64e-2)" "unprognostic (6.25e-3)" "unprognostic (1.26e-2)" "unprognostic (5.59e-5)" "unprognostic (1.36e-2)" "unprognostic (9.41e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" 0.3 3.4 44.2 0.1 79.7 0.1 0.2 81.1 84.6 2.9 5.2 0.8 0.3 1.2 0.3 6.5 1.6 0.1 2.2 43.4 70.4 0.4 0.1 15.9 0.0 85.8 72.4 0.2 0.8 0.3 2.8 0.0 90.7 1.3 0.1 3.9 1.7 2.8 0.2 15.0 0.5 0.6 57.1 0.1 0.9 0.8 86.3 0.3 13.0 0.1 0.3 0.2 2.5 112.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.6 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.2 79.7 81.1 84.6 43.4 70.4 85.8 72.4 90.7 57.1 86.3 112.6 0.0 0.0 22.2 2.0 0.0 2.3 0.0 0.0 0.0 2.7 0.1 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.8 0.0 17.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.4 0.0 0.3 0.1 40.9 2.8 0.0 1.2 0.0 6.6 58.4 0.1 0.0 7.2 0.0 0.0 0.0 0.8 0.0 2.9 0.0 0.0 0.6 0.1 0.1 1.4 0.6 0.0 0.0 0.9 0.0 0.0 LGI4 ENSG00000153902 "Leucine rich repeat LGI family member 4" Q8N135 19 35124513-35142451 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.7;Distal enterocytes: 33.1;Muller glia cells: 95.5;Sertoli cells: 78.9;Smooth muscle cells: 104.4" "Group enriched" "Detected in many" 6 "glioma: 4.5;melanoma: 11.5;renal cancer: 13.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 27 "WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042116, HPA043556" Approved Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA042116: AB_2677855, HPA043556: AB_2678550" "unprognostic (3.79e-1)" "unprognostic (6.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-2)" "unprognostic (3.71e-2)" "unprognostic (2.12e-2)" "unprognostic (4.26e-2)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.71e-2)" "unprognostic (4.47e-1)" "unprognostic (7.73e-2)" "unprognostic (7.13e-2)" 77.6 5.4 71.2 4.1 72.3 0.2 36.1 70.3 98.4 99.9 52.1 100.5 3.6 35.5 2.3 15.0 43.7 5.0 39.4 67.8 61.3 4.7 8.0 14.3 2.1 86.5 68.4 13.3 6.4 1.4 4.4 3.6 70.1 37.2 3.7 7.2 12.2 13.3 39.1 21.2 35.1 4.8 72.8 1.9 27.0 2.7 72.0 0.5 19.1 5.4 0.5 33.5 79.3 81.4 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 71.2 72.3 70.3 98.4 67.8 61.3 86.5 68.4 70.1 72.8 72.0 81.4 13.3 0.0 0.0 74.7 0.2 2.5 0.6 0.3 3.4 0.8 1.5 1.5 17.1 0.0 0.8 1.8 2.1 0.0 0.2 33.1 0.0 0.0 0.1 0.2 2.8 5.4 1.8 0.0 21.9 0.0 0.3 12.7 0.0 0.2 0.0 0.0 7.9 2.0 0.1 0.0 2.2 0.9 0.0 0.0 4.6 0.3 14.6 0.7 10.6 5.6 0.1 95.5 0.0 2.0 9.2 0.1 21.8 7.2 0.3 1.2 1.1 0.1 0.9 3.1 78.9 7.9 104.4 2.8 2.8 0.8 2.4 0.0 0.7 0.0 0.7 1.1 LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone subunit beta" P01229 19 49015980-49017091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 248 "pituitary gland: 4493.5" "Cell type enhanced" "Detected in some" "Early spermatids: 3.7;Late spermatids: 4.1;Pancreatic endocrine cells: 8.2;Syncytiotrophoblasts: 10.3" "Cancer enhanced" "Detected in many" "melanoma: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;HEK 293: 1.5;Hep G2: 1.4;K-562: 1.3;U-266/84: 2.0" "CAB022241, CAB022707, HPA038925" Enhanced Approved Cytosol "Secreted to blood" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB022241: , CAB022707: , HPA038925: AB_2676272" "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (2.34e-3)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (5.69e-2)" "unprognostic (7.04e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (9.52e-2)" "unprognostic (4.86e-2)" 1.0 5.1 0.2 0.0 0.1 0.0 0.6 0.4 0.3 0.5 0.0 0.5 1.3 0.5 0.0 1.3 0.6 0.0 0.9 0.1 0.2 1.4 1.9 0.9 0.2 0.2 0.1 0.6 18.0 0.6 4493.5 0.0 0.2 0.9 0.0 0.0 1.1 0.0 0.5 3.1 1.5 0.0 0.0 1.2 4.5 5.0 0.1 0.0 0.8 0.0 0.0 0.3 0.6 0.3 0.1 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.9 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.3 0.3 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.7 0.4 0.4 0.0 0.6 1.2 0.6 0.5 0.0 0.6 0.0 0.5 0.0 0.0 0.9 0.6 0.0 0.1 0.1 2.0 0.3 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.4 0.3 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.5 0.0 0.0 0.1 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.0 3.7 0.3 0.0 0.2 0.0 0.0 0.0 0.9 1.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 4.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.2 1.1 1.6 0.0 0.0 10.3 0.1 0.1 0.1 0.1 LIF "CDF, DIA, HILDA" ENSG00000128342 "LIF interleukin 6 family cytokine" P15018 22 30240453-30246759 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.7;urinary bladder: 91.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 95.5;Club cells: 56.3;Endometrial ciliated cells: 71.7;Fibroblasts: 51.9;Glandular and luminal cells: 192.9;granulocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 88.3;hTEC/SVTERT24-B: 113.0;hTERT-RPE1: 104.4;U-138 MG: 123.9;U-251 MG: 94.5;U-87 MG: 97.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018844, CAB025985" Uncertain Supported Cytosol "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" Cytosol "CAB025985: , HPA018844: AB_1852814" "unprognostic (1.28e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (8.79e-2)" "unprognostic (4.61e-2)" "unprognostic (7.36e-3)" "unprognostic (4.18e-3)" "unprognostic (1.17e-2)" "unprognostic (1.41e-2)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (6.78e-8)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (8.99e-2)" "unprognostic (4.71e-3)" 37.9 4.3 0.6 22.4 0.7 1.6 4.7 0.6 1.7 6.8 6.6 7.5 6.7 11.7 0.6 3.1 9.8 47.7 18.4 0.9 0.8 14.2 5.0 29.9 4.3 1.2 1.3 2.3 13.4 0.4 10.4 2.7 0.9 12.0 8.0 3.0 4.9 2.1 0.8 10.7 9.3 8.3 1.1 1.5 7.8 0.6 2.6 1.3 5.4 1.0 1.7 91.0 2.4 1.1 29.0 47.9 1.3 10.6 0.0 3.9 17.1 4.1 17.2 5.1 12.1 7.7 47.3 0.0 10.1 0.2 88.3 7.3 1.1 13.1 6.9 6.8 2.1 3.7 19.7 10.9 4.5 0.1 36.7 4.3 2.5 113.0 3.3 104.4 0.0 0.2 0.8 0.1 22.6 21.5 0.6 0.1 1.8 27.0 29.5 0.9 15.9 0.0 40.7 11.0 0.2 0.6 4.9 0.4 8.8 5.0 1.0 0.5 0.3 123.9 45.3 47.3 94.5 0.0 0.2 0.1 97.4 0.1 58.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.7 0.6 1.7 0.9 0.8 1.2 1.3 0.9 1.1 2.6 1.1 0.6 22.4 44.2 0.3 0.0 3.4 14.0 95.5 0.0 0.1 40.0 10.9 0.2 10.0 56.3 5.5 0.0 0.2 2.9 3.9 0.0 39.6 0.3 71.7 16.2 3.6 0.0 0.0 0.0 3.4 0.7 51.9 0.5 192.9 67.0 0.2 0.0 0.0 1.1 0.0 0.0 3.5 10.2 0.6 3.2 0.0 0.0 3.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 40.3 3.8 0.0 0.4 15.7 5.3 1.0 15.6 0.2 0.0 17.7 30.2 0.1 0.2 1.5 2.8 0.3 5.5 0.1 7.1 20.3 LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "Hofbauer cells: 22.0;Kupffer cells: 79.9;Macrophages: 39.1;monocytes: 48.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cell line enhanced" "Detected in some" "NB-4: 1.7;REH: 2.0;THP-1: 4.0;U-937: 9.1" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" 5.2 3.2 0.9 2.8 1.0 15.5 1.8 1.0 1.5 0.9 0.9 1.5 0.2 1.0 0.2 0.9 4.0 0.4 1.9 1.0 1.0 1.4 3.4 10.3 0.2 2.0 1.2 0.8 1.4 0.1 0.8 0.1 2.0 1.4 0.2 0.2 1.7 0.1 0.5 0.7 1.7 0.4 1.1 57.4 1.6 0.8 1.6 0.2 0.8 0.2 0.3 2.2 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 5.3 7.6 3.0 0.1 11.6 0.1 0.1 0.1 0.1 3.3 0.3 0.1 0.1 31.6 0.4 11.3 0.7 0.1 6.1 0.9 1.0 1.0 1.5 1.0 1.0 2.0 1.2 2.0 1.1 1.6 1.8 0.2 3.2 3.0 0.0 0.3 0.3 1.6 0.0 0.0 0.9 0.4 0.1 0.5 1.5 1.8 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.8 0.0 0.2 0.2 0.6 0.0 0.1 6.3 0.1 0.4 0.4 22.0 0.0 0.0 0.0 0.0 79.9 5.9 0.6 0.0 39.1 0.0 8.4 48.7 0.0 2.1 0.0 0.1 0.0 0.0 0.0 1.1 1.0 0.0 0.1 1.5 0.6 0.0 2.1 0.3 0.3 0.3 0.0 0.1 0.4 1.4 0.0 0.0 0.6 LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.5;lymphoid tissue: 76.3" "Group enriched" "Detected in some" 5 "Kupffer cells: 64.1;Macrophages: 136.1;monocytes: 53.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.7;neutrophil: 137.2;non-classical monocyte: 311.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.2;monocytes: 311.7" "Cell line enriched" "Detected in single" 31 "RPMI-8226: 4.1" "Secreted to blood" NA NA 670000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (8.52e-2)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (6.56e-2)" "unprognostic (2.90e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (6.61e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (3.61e-2)" "unprognostic (6.51e-3)" "unprognostic (4.68e-2)" "unprognostic (6.21e-2)" 7.9 1.3 0.2 36.9 0.2 43.5 1.9 0.2 0.9 0.7 0.6 1.8 0.0 1.0 0.0 0.9 4.1 1.7 2.5 0.3 0.2 1.8 3.8 22.2 0.5 0.6 0.3 0.6 0.9 0.0 0.9 1.6 0.5 1.4 1.2 0.0 1.2 0.0 0.7 0.3 2.8 6.9 0.3 76.3 2.1 0.3 0.4 0.4 1.0 0.0 0.4 15.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 128.6 0.5 0.0 252.7 0.3 0.0 0.0 0.0 39.2 0.1 0.0 0.0 137.2 0.3 311.7 20.3 0.1 65.0 0.2 0.2 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.3 0.4 0.4 0.1 0.0 8.5 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 3.1 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 1.0 0.0 0.0 11.4 0.0 0.4 0.7 6.5 0.0 0.1 0.0 0.0 64.1 14.3 0.0 0.0 136.1 0.0 0.0 53.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.4 2.2 0.0 0.0 0.8 0.2 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 LIPC "HL, HTGL" ENSG00000166035 "Lipase C, hepatic type" P11150 15 58410569-58569844 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "liver: 171.0" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 161.7" "Group enriched" "Detected in some" 14 "liver cancer: 20.4;renal cancer: 10.4" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;NK-cells: 1.5;T-cells: 1.8" "Cell line enhanced" "Detected in some" "CACO-2: 8.5;EFO-21: 6.1;Hep G2: 24.4;HMC-1: 6.8;MOLT-4: 5.5;U-2197: 18.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 5500000 "Cluster 10: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.76e-2)" "unprognostic (9.15e-3)" "unprognostic (7.89e-2)" "unprognostic (7.15e-4)" "unprognostic (1.40e-1)" "unprognostic (1.33e-2)" "unprognostic (9.93e-3)" "unprognostic (6.25e-2)" "unprognostic (3.79e-2)" "unprognostic (1.10e-2)" "unprognostic (3.06e-1)" "unprognostic (2.31e-1)" "unprognostic (2.82e-2)" "unprognostic (1.41e-1)" "unprognostic (2.87e-2)" "unprognostic (1.80e-2)" "unprognostic (2.27e-2)" 0.4 0.1 0.5 0.3 0.5 0.2 1.5 0.8 0.9 0.4 0.0 0.6 1.8 0.2 0.9 0.6 1.0 0.8 0.5 0.6 0.3 6.0 171.0 0.3 0.7 0.8 0.7 0.8 2.5 0.0 1.5 0.4 1.0 0.1 0.8 0.1 0.2 0.9 0.0 0.6 0.8 0.1 0.6 0.8 0.5 0.1 0.4 2.1 1.2 0.3 0.2 1.6 0.3 1.2 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.1 0.8 0.0 0.0 8.5 0.0 0.0 6.1 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 3.0 0.0 24.4 0.5 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.2 0.1 5.5 0.8 0.0 0.1 0.0 1.1 0.3 0.0 2.6 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 18.4 0.0 0.1 0.0 0.1 0.2 0.5 0.0 1.6 0.1 0.0 1.3 0.1 1.8 0.0 0.3 0.9 0.1 0.0 0.4 1.3 0.2 1.5 0.2 0.0 0.9 1.1 0.5 0.5 0.8 0.9 0.6 0.3 0.8 0.7 1.0 0.6 0.4 1.2 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.8 11.5 0.7 3.7 0.0 0.0 0.9 1.2 5.9 7.8 0.0 0.4 0.5 1.2 0.0 2.7 6.1 3.7 0.1 2.9 0.5 2.7 0.0 0.2 4.2 161.7 0.1 0.0 4.3 0.0 0.0 3.8 0.8 0.1 0.3 0.3 1.8 16.9 0.6 0.0 3.1 0.0 12.9 0.2 0.0 0.0 0.0 0.2 0.3 15.7 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.3 0.6 0.0 1.1 1.2 0.0 0.1 LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 142 "stomach 1: 37213.5" "Cell type enriched" "Detected in some" 444 "Gastric mucus-secreting cells: 1509.7" "Cancer enriched" "Detected in some" 75 "stomach cancer: 278.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 4.1;MOLT-4: 3.4;NTERA-2: 3.4;REH: 2.1;RPMI-8226: 1.8;THP-1: 6.8;U-2 OS: 2.2;U-266/70: 3.1" "Region enriched" "Detected in single" 77 "olfactory bulb: 7.6" HPA045930 Enhanced "Secreted to digestive system" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA045930: AB_10959518" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" 6.3 2.8 0.0 0.0 0.0 0.0 4.6 0.1 0.0 3.9 0.0 13.0 262.0 1.9 0.0 117.9 5.4 0.0 3.2 0.0 0.0 11.4 4.9 7.3 0.0 0.3 0.1 2.2 4.5 0.0 7.3 0.5 0.1 6.7 0.0 0.0 2.6 0.0 1.6 2.0 1.9 0.0 0.0 2.6 37213.5 2.9 0.0 0.0 1.3 0.0 0.1 2.5 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 3.4 0.0 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 2.2 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1509.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "placenta: 149.3;thyroid gland: 242.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Extravillous trophoblasts: 67.9;Glandular and luminal cells: 49.0;Hepatocytes: 78.2" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 20.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 122.6;HaCaT: 189.8;RPTEC TERT1: 122.4;TIME: 247.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA016966 Uncertain "Secreted to blood" NA NA 657000000 810000 "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA016966: AB_1852893" "unprognostic (2.20e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.25e-3)" "unprognostic (6.38e-2)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" "unprognostic (4.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.44e-1)" "unprognostic (6.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.35e-1)" 4.6 0.2 0.9 16.3 0.6 0.3 1.0 4.0 2.6 0.9 1.7 5.9 6.4 1.4 2.9 1.3 0.5 14.0 1.2 3.2 0.7 6.7 34.7 7.2 1.8 2.8 2.8 0.2 1.9 0.2 0.4 149.3 1.6 1.5 7.2 4.9 0.5 20.9 2.5 1.4 7.2 7.7 1.4 0.4 1.7 7.0 3.7 1.9 242.5 0.1 1.7 14.4 0.6 1.2 2.2 0.3 53.6 122.6 0.5 0.1 0.9 0.6 5.8 0.0 0.1 54.5 19.6 0.2 29.7 0.0 37.2 189.8 8.1 39.0 0.0 0.6 0.3 0.1 0.2 0.3 8.1 0.1 0.8 5.4 43.0 19.1 36.8 0.3 28.0 0.2 0.3 0.3 0.0 0.0 0.0 0.2 8.1 1.4 0.5 0.1 0.0 3.0 122.4 14.8 0.8 0.1 1.0 1.4 0.1 6.9 0.2 0.2 247.4 0.2 0.1 0.1 0.6 0.1 0.0 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.6 4.0 2.6 3.2 0.7 2.8 2.8 1.6 1.4 3.7 1.2 0.3 0.0 1.1 0.7 0.3 1.8 5.6 3.3 0.0 0.6 2.8 1.9 1.8 24.3 3.5 14.7 60.5 5.5 0.1 9.3 0.0 3.3 8.4 19.1 8.3 7.9 13.8 0.0 0.2 1.4 67.9 6.0 2.6 49.0 0.0 11.5 5.3 78.2 1.8 0.0 0.3 5.3 2.0 1.9 0.0 8.1 0.3 0.8 1.8 2.8 0.7 1.1 0.0 1.0 0.2 12.8 2.7 0.0 0.3 10.6 10.1 1.3 0.5 2.9 0.0 1.0 2.0 1.4 0.9 0.4 2.6 19.4 1.1 0.1 11.2 11.4 LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.7;stomach 1: 48.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 144.2;Club cells: 135.5;Distal enterocytes: 312.3;Gastric mucus-secreting cells: 236.5;Intestinal goblet cells: 139.8;Proximal enterocytes: 226.1;Urothelial cells: 158.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 74.1;OE19: 17.2;RPTEC TERT1: 36.7;T-47d: 17.6;U-266/84: 18.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA049079 Approved "Secreted to blood" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA049079: AB_2680623" "unprognostic (4.50e-3)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (3.38e-1)" "unprognostic (1.01e-1)" "unprognostic (8.59e-2)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (7.88e-2)" "prognostic favorable (9.20e-5)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (4.21e-4)" "unprognostic (1.15e-1)" 0.3 0.3 0.3 2.8 0.6 0.1 3.8 0.1 0.6 2.8 6.9 36.3 11.1 0.2 7.1 14.7 1.1 12.3 0.4 0.4 1.6 7.8 0.4 18.3 0.1 0.1 0.1 0.5 5.5 0.0 0.3 0.1 0.1 6.8 37.7 0.2 13.2 2.0 0.5 7.4 11.8 0.6 0.0 0.4 48.2 2.7 0.2 0.3 0.2 0.1 3.0 12.2 4.3 0.1 10.3 13.5 0.1 0.1 0.0 0.2 2.9 0.3 0.0 0.3 0.3 1.3 74.1 0.0 7.5 0.2 2.9 3.6 5.6 0.1 0.4 0.1 1.6 1.8 1.8 1.4 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 5.4 0.1 0.0 1.3 0.5 0.1 0.7 17.2 1.1 0.0 0.0 1.0 36.7 9.2 0.0 0.0 1.1 12.2 0.3 0.6 17.6 0.3 0.0 0.1 1.1 0.1 0.2 1.2 18.9 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.1 0.6 0.4 1.6 0.1 0.1 0.1 0.0 0.2 0.1 0.1 144.2 38.5 2.0 0.8 0.8 16.3 76.5 0.6 0.7 55.6 12.7 0.4 94.4 135.5 68.0 0.0 0.2 1.0 312.3 1.9 57.8 0.2 7.0 0.5 1.8 22.2 0.0 1.7 24.9 0.1 1.1 236.5 5.7 7.0 36.0 1.1 0.3 0.0 0.0 0.9 139.8 38.7 0.3 0.3 0.1 0.0 2.4 16.0 0.0 0.8 0.3 2.1 2.5 0.4 60.4 102.7 0.0 0.3 72.8 226.1 1.6 105.6 0.9 0.0 0.1 5.5 1.1 0.3 6.9 2.0 0.3 0.8 12.0 102.1 158.0 LIPI "CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5" ENSG00000188992 "Lipase I" Q6XZB0 21 14108813-14210955 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "epididymis: 421.0" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Excitatory neurons: 1.5;Inhibitory neurons: 2.0;Microglial cells: 1.9;Oligodendrocyte precursor cells: 2.0" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049665 Supported "Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA049665: " "unprognostic (2.60e-2)" "unprognostic (3.49e-1)" "unprognostic (1.12e-3)" "unprognostic (1.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.53e-2)" "unprognostic (2.90e-1)" "unprognostic (3.64e-13)" "unprognostic (2.82e-1)" "unprognostic (4.14e-2)" "unprognostic (2.90e-1)" "unprognostic (7.87e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.0 0.5 421.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.2 0.7 0.4 0.0 0.1 0.6 0.1 0.4 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LIPK "bA186O14.2, LIPL2" ENSG00000204021 "Lipase family member K" Q5VXJ0 10 88724544-88752756 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-BR-3: 2.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 8: SK-BR-3 - Unknown function" "unprognostic (7.65e-2)" "unprognostic (8.64e-2)" "unprognostic (3.57e-2)" "unprognostic (3.19e-7)" "unprognostic (1.25e-1)" "unprognostic (1.60e-2)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 LIPM "bA304I5.1, LIPL3" ENSG00000173239 "Lipase family member M" Q5VYY2 10 88802730-88820546 "Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 28.0" "Cell type enriched" "Detected in single" 11 "Suprabasal keratinocytes: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071276 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "Endoplasmic reticulum" "HPA071276: " "unprognostic (7.72e-2)" "unprognostic (8.49e-4)" "unprognostic (1.42e-2)" "unprognostic (2.23e-4)" "unprognostic (6.70e-3)" "unprognostic (3.01e-3)" "unprognostic (5.75e-2)" "unprognostic (6.63e-2)" "unprognostic (5.61e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.59e-2)" "unprognostic (5.93e-2)" "unprognostic (7.05e-3)" "unprognostic (4.17e-2)" "unprognostic (9.02e-2)" "unprognostic (9.70e-6)" 0.1 0.0 0.0 0.2 0.0 0.1 1.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 28.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 LIPN "bA186O14.3, LIPL4" ENSG00000204020 "Lipase family member N" Q5VXI9 10 88759982-88779626 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase Ichthyosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "skin 1: 26.7" "Group enriched" "Detected in some" 4 "Macrophages: 7.5;monocytes: 2.5" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 2.9;eosinophil: 10.3;intermediate monocyte: 7.5;neutrophil: 5.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 8 "granulocytes: 10.3;monocytes: 8.5" "Cell line enhanced" "Detected in single" "HL-60: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.03e-2)" "unprognostic (9.75e-2)" "unprognostic (2.54e-2)" "unprognostic (4.40e-2)" "unprognostic (5.77e-3)" "unprognostic (1.65e-1)" 1.3 0.3 0.0 2.8 0.0 2.8 1.7 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 26.7 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 2.9 10.3 0.0 7.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 5.4 0.0 8.5 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 7.5 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 LLCFC1 "C7orf34, CTM-1" ENSG00000165131 "LLLL and CFNLAS motif containing 1" Q96L11 7 142939343-142940868 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "testis: 66.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "unprognostic (5.05e-2)" "unprognostic (9.94e-2)" "unprognostic (5.49e-3)" "unprognostic (2.76e-2)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.85e-3)" "unprognostic (3.54e-1)" "unprognostic (2.02e-1)" 0.1 0.0 0.3 0.0 3.6 1.6 0.1 2.2 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 2.8 0.2 0.0 0.2 0.2 6.5 3.3 0.0 0.0 0.0 0.0 0.0 4.4 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 3.0 1.1 0.0 66.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 3.6 2.2 2.0 0.4 2.8 6.5 3.3 4.4 3.0 3.3 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.1;Club cells: 38.4;Early spermatids: 41.9;Endometrial stromal cells: 34.0;Extravillous trophoblasts: 44.2;Fibroblasts: 79.1;Peritubular cells: 39.1;Smooth muscle cells: 32.7" "Cancer enhanced" "Detected in all" "renal cancer: 39.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 777.3;fHDF/TERT166: 1790.7;HSkMC: 356.3;U-138 MG: 475.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 550000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" 27.9 2.4 0.4 6.8 0.4 0.2 17.6 0.5 0.9 10.8 0.8 4.2 3.8 6.2 1.7 5.6 8.9 18.8 23.9 0.3 0.4 4.5 2.1 13.6 3.3 1.3 1.4 5.4 3.3 0.9 1.2 8.1 0.8 4.1 4.5 1.1 3.2 2.6 1.9 12.4 3.7 10.0 1.2 2.6 4.4 1.4 0.5 0.9 6.9 2.1 1.4 14.1 4.8 1.0 0.8 0.2 2.0 0.9 168.7 185.2 0.1 777.3 205.3 73.2 246.4 0.5 0.3 0.1 16.5 1790.7 3.7 0.2 4.5 3.5 196.4 0.1 2.0 0.0 16.3 9.3 203.4 0.4 0.1 356.3 4.4 137.6 7.4 329.3 95.3 0.1 0.0 0.1 83.6 0.0 0.1 0.3 6.4 0.1 1.9 0.1 7.4 0.9 4.9 0.5 0.5 4.2 72.1 0.1 12.9 29.8 0.6 0.6 6.8 475.5 23.2 272.8 9.3 0.0 0.1 0.2 207.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.3 0.4 1.3 1.4 0.8 1.2 0.5 1.0 20.0 9.6 1.1 0.0 0.2 7.8 1.9 67.1 0.0 0.6 1.3 1.1 2.1 0.0 38.4 0.0 0.0 0.8 0.1 0.0 0.0 7.2 41.9 8.4 34.0 9.4 0.0 0.0 0.3 0.6 44.2 79.1 0.0 6.6 0.0 0.1 10.8 0.5 2.2 1.7 2.0 0.0 2.0 0.8 21.6 5.0 14.0 1.3 5.4 1.9 0.6 0.0 0.0 0.0 0.0 1.3 0.0 39.1 0.3 2.8 0.0 0.1 8.3 1.7 19.7 1.1 32.7 0.8 0.6 1.8 10.7 4.8 1.1 0.4 0.1 0.9 LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.3;Extravillous trophoblasts: 145.8;Fibroblasts: 76.0;Smooth muscle cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cell line enhanced" "Detected in many" "BJ: 66.5;BJ hTERT+: 75.2;hTERT-RPE1: 73.7;U-87 MG: 61.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" 12.4 3.1 1.4 5.4 0.8 0.8 6.8 0.2 1.4 12.7 12.3 10.2 1.9 16.0 1.4 4.7 8.3 5.0 27.9 1.7 1.9 8.7 1.5 10.1 4.4 1.4 1.7 8.0 3.3 2.2 9.2 8.0 1.1 15.3 1.4 0.0 7.6 11.9 3.8 6.4 5.6 4.9 0.8 3.2 7.8 2.4 1.9 0.9 5.2 1.9 2.3 16.6 14.8 0.6 3.3 0.0 0.9 0.0 45.6 54.8 2.2 66.5 75.2 27.6 48.7 1.3 1.7 0.0 12.1 49.1 6.9 19.9 0.3 0.2 6.5 0.0 4.3 0.2 2.0 0.3 6.2 0.0 0.1 45.0 0.0 20.8 0.2 73.7 1.0 1.2 0.0 0.3 33.3 2.4 0.4 1.3 6.3 4.4 45.1 0.0 38.7 0.6 2.5 12.0 5.5 0.0 2.0 0.4 0.0 6.5 0.4 0.0 4.9 53.8 47.0 42.8 25.8 0.2 0.0 0.0 61.9 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 1.3 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 3.4 0.2 1.4 0.8 0.2 1.4 1.7 1.9 1.4 1.7 1.1 0.8 1.9 0.6 4.1 0.0 0.6 3.3 0.1 5.9 7.6 6.0 4.0 0.9 2.3 4.8 92.3 2.8 0.9 9.2 0.0 2.2 0.6 0.1 3.9 5.2 1.7 9.2 8.0 4.1 3.5 0.0 0.5 1.3 145.8 76.0 8.6 9.3 1.3 5.5 12.1 0.1 6.6 0.0 0.4 0.6 2.0 0.0 6.2 1.3 9.9 0.9 10.6 0.0 0.1 6.4 0.0 1.5 0.3 12.2 0.1 21.1 0.1 4.8 0.4 2.5 1.2 0.4 0.0 6.0 32.7 8.9 4.9 2.4 3.4 5.1 3.4 0.3 1.1 5.0 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 LOXL3 ENSG00000115318 "Lysyl oxidase like 3" P58215 2 74532258-74555690 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Oxidoreductase "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Hofbauer cells: 17.9;Kupffer cells: 12.5;Macrophages: 12.3;Microglial cells: 30.0;Muller glia cells: 10.6;Oligodendrocyte precursor cells: 11.6;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "melanoma: 15.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 11.7;non-classical monocyte: 9.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 143.4;HDLM-2: 110.7;U-138 MG: 245.9;WM-115: 549.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035281 Approved "Secreted to extracellular matrix" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA035281: AB_10601766" "unprognostic (7.54e-2)" "unprognostic (2.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.55e-3)" "unprognostic (6.85e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-3)" "unprognostic (6.84e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.22e-2)" "unprognostic (7.33e-3)" "unprognostic (7.09e-2)" "unprognostic (3.38e-2)" 6.8 5.3 4.5 7.8 4.7 14.3 3.0 4.5 5.3 5.1 3.8 7.3 4.0 7.4 1.7 3.2 4.9 6.5 8.2 4.5 5.6 2.0 1.5 4.6 4.1 7.0 5.0 2.9 1.1 1.7 2.7 15.9 6.3 3.3 3.7 4.9 1.6 4.0 1.3 2.0 3.9 8.1 5.6 8.9 2.7 2.6 7.0 1.4 2.2 1.5 2.3 5.2 4.0 7.3 1.6 0.3 21.8 3.7 17.1 20.6 4.5 71.0 143.4 33.8 31.8 25.6 1.3 0.1 0.9 73.1 1.6 1.1 2.8 1.8 19.8 110.7 1.0 17.6 1.8 0.2 5.7 0.6 16.7 22.6 0.2 90.6 3.8 12.0 0.7 0.8 0.8 2.8 6.4 4.1 0.2 6.5 12.0 0.8 0.7 2.0 3.1 0.3 0.3 1.2 11.2 12.8 0.6 1.1 14.7 3.2 2.3 1.3 0.3 245.9 8.2 1.4 0.9 1.4 0.5 0.1 92.5 6.8 549.6 0.1 6.0 0.3 0.0 11.7 0.0 0.1 0.1 0.0 3.5 0.1 0.0 0.0 2.5 0.0 9.3 0.4 0.0 2.6 4.5 4.7 4.5 5.3 4.5 5.6 7.0 5.0 6.3 5.6 7.0 7.3 0.9 0.0 0.5 14.0 0.3 0.9 0.2 0.6 0.6 0.9 0.4 0.8 0.3 1.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.8 0.0 0.2 4.8 1.2 0.0 0.4 0.4 0.0 1.5 7.1 0.0 0.5 1.3 0.7 0.4 0.1 17.9 1.7 4.2 0.1 0.0 12.5 2.5 0.7 5.0 12.3 0.0 30.0 4.8 10.6 1.0 11.6 0.6 0.3 0.0 4.5 0.1 0.3 0.0 0.1 0.0 0.9 19.7 1.6 5.3 0.6 0.8 0.1 0.1 0.8 0.4 0.2 0.0 0.2 LOXL4 "FLJ21889, LOXC" ENSG00000138131 "Lysyl oxidase like 4" Q96JB6 10 98247690-98268194 "Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Basal respiratory cells: 141.0" "Cancer enhanced" "Detected in all" "melanoma: 44.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BJ hTERT+: 249.7;CAPAN-2: 301.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033876, HPA037609" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB033876: AB_2135101, HPA037609: AB_2675579" "unprognostic (9.91e-3)" "unprognostic (3.97e-2)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (7.71e-2)" "unprognostic (1.75e-2)" "unprognostic (8.38e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.57e-4)" "unprognostic (2.51e-1)" "unprognostic (4.97e-2)" "unprognostic (5.25e-2)" "unprognostic (5.77e-3)" "unprognostic (1.28e-1)" "unprognostic (6.10e-2)" "unprognostic (7.40e-3)" 8.2 2.4 0.7 1.6 0.9 0.5 11.9 1.1 0.7 11.8 2.3 10.4 1.9 7.0 3.0 2.0 7.8 1.8 3.0 0.8 1.2 6.6 6.0 4.4 0.4 1.3 1.3 7.1 6.6 1.2 1.9 5.8 1.3 6.6 1.8 2.6 19.6 10.8 8.3 4.0 3.2 7.6 1.0 2.7 2.9 5.5 1.0 1.4 7.0 1.5 0.7 5.0 7.4 1.0 0.0 1.6 0.1 0.3 6.9 29.5 0.9 32.1 249.7 2.6 26.6 5.4 301.6 0.1 28.4 25.1 1.1 0.3 0.1 0.0 2.2 0.0 0.2 0.0 4.4 13.3 6.7 0.0 0.0 3.3 0.0 4.4 0.0 0.4 0.1 0.0 0.3 0.0 0.4 0.0 0.0 2.3 0.6 0.1 0.5 0.1 2.9 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 8.7 0.2 0.7 0.7 0.2 53.7 3.2 1.1 0.0 0.0 0.2 0.5 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.7 0.9 1.1 0.7 0.8 1.2 1.3 1.3 1.3 1.0 1.0 1.0 0.3 6.4 1.5 0.7 0.3 0.9 2.1 141.0 0.0 0.4 6.5 6.5 1.6 4.3 17.5 31.3 0.0 0.2 1.7 0.1 0.0 11.1 0.3 1.5 1.2 0.9 0.0 0.0 0.1 0.5 0.4 6.0 0.0 4.2 1.3 1.1 2.2 0.4 0.2 0.0 0.1 0.2 8.2 0.0 2.1 0.4 4.1 0.2 0.0 9.4 0.0 5.4 0.0 0.0 0.0 3.0 0.0 1.5 0.3 7.9 0.0 0.4 6.3 0.1 0.0 5.2 2.2 0.1 0.2 0.1 0.9 0.4 0.2 0.7 0.0 3.4 LPA "LP, Lp(a)" ENSG00000198670 Lipoprotein(a) P08519 6 160531482-160664275 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Hydrolase, Protease, Serine protease" Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 76.7" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 80.7" "Cancer enriched" "Detected in single" 38 "liver cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "RT4: 1.0" "CAB016072, HPA060604" Supported "Secreted to blood" NA NA 78800000000 1800000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB016072: AB_2135240, HPA060604: AB_2684330" "unprognostic (2.16e-1)" "unprognostic (5.10e-1)" "unprognostic (7.75e-3)" "unprognostic (6.70e-2)" "unprognostic (1.60e-1)" "unprognostic (4.17e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-3)" "unprognostic (3.63e-2)" "unprognostic (3.18e-1)" "unprognostic (7.45e-3)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (3.72e-2)" 0.0 0.1 2.0 0.0 1.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.8 0.0 0.0 0.8 6.3 0.5 76.7 0.1 0.0 1.8 1.9 0.2 0.6 0.0 0.0 0.0 1.3 0.6 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 4.2 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.2 0.0 1.1 0.8 6.3 1.8 1.9 1.3 0.2 4.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.2 0.0 2.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 80.7 0.0 0.0 1.3 0.0 0.0 2.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 404 "salivary gland: 1026.8" "Group enriched" "Detected in some" 6 "Breast glandular cells: 25.2;Early spermatids: 8.3;Late spermatids: 14.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "THP-1: 9.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 43: THP-1 - Innate immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1026.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 2.5 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.7 25.2 0.5 0.7 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 8.3 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.4 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.0 14.1 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.5 1.4 0.1 0.0 0.3 0.0 0.2 0.1 2.6 0.4 0.0 0.3 0.0 0.2 0.0 0.5 0.5 LRCOL1 ENSG00000204583 "Leucine rich colipase like 1" A6NCL2 12 132603150-132610582 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "epididymis: 50.1" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 33.2" "Group enriched" "Detected in some" 4 "endometrial cancer: 0.8;liver cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (5.09e-3)" "unprognostic (7.83e-3)" "unprognostic (3.26e-1)" "unprognostic (6.94e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-2)" "prognostic favorable (7.04e-4)" "unprognostic (4.54e-2)" "unprognostic (6.08e-2)" "unprognostic (5.29e-2)" "unprognostic (4.66e-3)" "unprognostic (1.52e-1)" "unprognostic (6.50e-6)" "unprognostic (1.46e-3)" "unprognostic (9.63e-2)" "unprognostic (3.31e-1)" "unprognostic (4.00e-3)" 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.2 50.1 0.1 0.4 0.0 0.0 0.0 0.1 0.2 2.3 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 1.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.3 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.6 1.9 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.0 0.1 3.3 33.2 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.1 0.0 0.2 0.4 0.0 0.0 LRG1 LRG ENSG00000171236 "Leucine rich alpha-2-glycoprotein 1" P02750 19 4536402-4540036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "liver: 944.2" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 793.0" "Cancer enriched" "Detected in many" 9 "liver cancer: 160.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 19 "neutrophil: 285.2" "Lineage enriched" "Detected in many" 44 "granulocytes: 285.2" "Cell line enhanced" "Detected in many" "Hep G2: 15.4;SK-BR-3: 15.7;THP-1: 26.2;U-937: 48.7" "Low region specificity" "Detected in single" "HPA001888, HPA001889" Enhanced Approved Vesicles "Secreted to blood" NA NA 21000000000 42000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA001888: AB_1079276, HPA001889: AB_1079275" "unprognostic (5.54e-3)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (1.42e-1)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (1.46e-3)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.66e-6)" "unprognostic (4.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.49e-4)" "unprognostic (2.60e-2)" 7.2 4.5 0.6 17.8 0.5 31.4 4.3 1.2 2.6 8.7 1.1 7.3 6.7 1.9 5.9 22.7 10.0 15.5 1.2 0.6 0.6 9.8 944.2 7.8 0.8 0.7 0.7 1.5 44.1 0.1 1.6 1.9 1.9 4.4 4.7 0.1 20.9 6.2 1.0 4.8 3.3 2.2 0.5 16.2 13.6 0.3 0.9 1.2 1.3 1.4 6.5 13.3 3.8 0.9 10.8 0.1 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 1.0 8.0 3.6 13.3 0.0 0.5 1.4 0.0 1.7 0.1 13.4 0.4 0.3 0.2 15.4 0.0 0.4 13.9 4.1 0.0 0.0 0.0 0.0 0.1 0.0 9.6 0.2 0.0 0.6 0.0 11.3 0.2 8.2 0.0 0.1 0.3 11.3 1.0 2.0 0.0 0.0 0.1 15.7 0.1 1.3 4.8 26.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 48.7 0.0 2.4 6.4 15.0 0.1 2.0 0.1 0.4 0.3 0.1 1.6 0.4 0.1 0.1 285.2 0.2 1.3 0.2 1.1 2.2 0.6 0.5 1.2 2.6 0.6 0.6 0.7 0.7 1.9 0.5 0.9 0.9 13.4 12.8 54.3 0.0 3.3 8.0 33.1 56.8 18.2 0.1 14.2 2.5 0.5 60.1 50.2 14.7 0.0 0.8 0.5 44.7 1.9 112.7 0.0 38.0 1.8 24.7 4.9 13.2 0.0 64.1 12.4 3.0 31.6 17.3 12.0 0.2 38.2 793.0 6.7 1.7 0.0 26.3 32.6 19.9 5.0 0.0 0.0 14.7 1.8 0.0 7.3 0.1 0.0 0.0 0.0 40.6 11.9 0.0 1.7 4.5 10.8 4.9 76.1 0.1 0.0 2.3 3.3 0.0 0.2 9.0 5.8 1.4 1.9 3.4 27.6 30.2 LRP8 "APOER2, HSZ75190, LRP-8, MCI1" ENSG00000157193 "LDL receptor related protein 8" Q14114 1 53242364-53328469 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.0;thyroid gland: 41.5" "Cell type enhanced" "Detected in many" "Astrocytes: 30.7;Bipolar cells: 45.3;Excitatory neurons: 35.9;Granulosa cells: 67.0;Inhibitory neurons: 116.4;Microglial cells: 43.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073031 Enhanced "Secreted in other tissues" NA NA 2000000 "Cluster 11: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "HPA073031: AB_2732217" "unprognostic (3.83e-2)" "unprognostic (6.06e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (3.46e-1)" "unprognostic (6.13e-2)" "unprognostic (1.03e-3)" "prognostic unfavorable (7.02e-4)" "unprognostic (6.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (9.11e-2)" "unprognostic (8.88e-16)" "unprognostic (7.73e-3)" "unprognostic (5.47e-2)" "unprognostic (6.98e-2)" "unprognostic (3.00e-2)" 1.9 1.4 13.6 4.9 14.2 5.3 1.4 13.6 15.4 1.9 15.5 1.4 1.4 1.6 1.8 7.5 2.7 1.3 1.2 13.7 13.3 1.4 0.3 2.9 5.2 11.2 10.6 1.1 0.7 0.4 5.2 2.0 12.9 1.1 1.8 11.9 1.5 1.2 0.7 1.6 2.1 2.0 7.9 2.6 1.0 24.0 13.4 2.8 41.5 0.4 4.8 1.6 2.7 13.3 22.2 37.4 18.0 22.5 10.1 10.3 22.9 30.5 19.1 32.4 24.2 10.4 23.2 29.3 29.5 13.3 48.0 35.7 13.3 25.2 15.9 22.2 11.4 20.8 43.3 20.2 9.5 38.2 31.9 3.4 2.7 33.1 17.0 5.8 26.6 24.8 7.5 14.6 6.5 23.6 21.1 19.8 34.8 21.0 27.4 32.1 25.8 31.6 15.6 15.3 38.7 15.3 13.1 67.0 14.6 11.3 8.4 25.1 25.5 9.5 14.6 23.1 51.4 25.6 37.5 12.8 47.9 54.4 53.3 1.4 0.4 0.2 0.5 0.1 0.4 0.3 0.3 0.3 0.2 0.4 0.2 0.3 1.3 0.4 0.1 1.3 0.5 0.2 13.6 14.2 13.6 15.4 13.7 13.3 11.2 10.6 12.9 7.9 13.4 13.3 0.8 0.0 6.1 30.7 2.2 1.5 2.5 1.6 0.0 45.3 1.2 0.8 2.6 0.0 4.3 0.0 0.0 2.1 8.9 0.3 0.0 2.1 7.4 4.4 2.5 4.1 2.4 3.4 35.9 2.4 1.8 1.7 0.0 10.1 1.3 67.0 0.7 0.1 1.9 26.9 116.4 2.2 2.0 3.2 2.1 5.1 0.6 2.4 0.0 43.1 7.0 1.5 5.2 17.6 2.4 4.4 0.2 2.6 4.4 13.7 0.0 0.1 10.2 2.8 0.0 2.8 2.2 3.6 1.1 4.4 1.4 9.7 3.0 1.8 0.8 8.1 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LTA "LT, TNFB, TNFSF1" ENSG00000226979 "Lymphotoxin alpha" P01374 6 31572054-31574324 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 1.9;lymphoid tissue: 5.6;testis: 4.2" "Group enriched" "Detected in some" 4 "B-cells: 13.7;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.2;MOLT-4: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA007729 Uncertain "Secreted to blood" NA NA 8150 "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA007729: AB_1852906" "unprognostic (3.76e-2)" "unprognostic (1.48e-2)" "unprognostic (1.36e-3)" "unprognostic (8.99e-5)" "unprognostic (3.22e-1)" "unprognostic (5.13e-3)" "unprognostic (2.07e-1)" "unprognostic (4.71e-2)" "unprognostic (3.10e-2)" "unprognostic (3.39e-4)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (8.72e-12)" "unprognostic (2.59e-1)" "unprognostic (5.49e-2)" "unprognostic (4.30e-2)" "unprognostic (3.03e-1)" 0.2 0.0 0.1 0.6 0.1 0.8 0.1 0.2 0.2 0.2 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.4 2.4 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.1 1.9 0.0 0.1 5.6 0.1 4.2 0.1 0.0 0.2 0.0 2.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.0 1.1 2.3 13.7 0.1 0.1 0.0 0.6 0.6 0.5 1.3 2.5 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 1.9 0.0 0.0 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.3 0.4 0.4 0.0 0.3 0.0 1.0 0.4 0.0 1.0 2.5 2.4 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.3 1.8 0.5 0.5 0.4 0.0 14.5 0.1 0.0 0.0 LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Fibroblasts: 116.1;Leydig cells: 90.4;Peritubular cells: 161.0;Skeletal myocytes: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 569.4;HSkMC: 185.3;HUVEC TERT2: 194.5;U-2197: 181.1;U-87 MG: 255.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" 22.9 13.1 7.8 22.1 9.4 11.5 14.5 7.1 7.5 161.4 10.5 27.2 10.2 58.9 37.8 21.2 37.0 73.0 89.0 8.8 9.1 38.6 18.6 27.5 6.9 12.1 10.6 30.2 7.9 2.4 9.0 73.2 9.2 46.9 16.5 0.7 14.6 73.6 15.7 10.8 15.0 96.7 9.1 8.3 32.8 17.9 8.8 8.2 6.5 28.4 18.7 53.9 28.3 13.4 0.3 12.5 31.3 0.3 26.1 569.4 13.5 46.5 95.7 6.4 9.3 25.3 4.6 41.3 1.0 6.0 8.8 2.4 0.7 1.5 22.0 0.6 15.3 135.6 15.0 4.1 118.6 0.5 15.7 185.3 4.4 141.2 6.9 61.8 194.5 6.3 8.7 0.3 51.1 19.9 5.5 0.2 22.4 1.0 39.2 4.7 65.8 0.6 0.4 22.4 6.3 3.4 9.5 72.1 0.8 49.1 27.9 0.4 126.4 6.4 26.2 181.1 37.6 74.8 80.0 58.8 255.9 5.2 10.8 3.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 5.3 7.8 9.4 7.1 7.5 8.8 9.1 12.1 10.6 9.2 9.1 8.8 13.4 33.6 0.0 0.6 108.4 0.4 13.5 5.6 13.0 10.2 0.0 6.9 6.6 80.9 4.3 3.6 1.8 0.0 45.2 0.3 12.9 0.0 9.6 6.3 7.3 18.3 28.1 1.2 30.3 30.4 6.5 23.4 116.1 10.2 10.5 0.0 11.8 20.3 11.0 7.6 0.0 54.3 2.8 2.0 0.3 18.1 7.1 90.4 12.0 19.6 39.4 0.4 0.2 0.0 70.4 52.4 19.1 3.3 161.0 1.3 19.1 0.7 0.3 6.3 0.3 59.2 85.8 67.9 0.7 11.9 6.9 9.8 43.5 2.0 2.6 4.1 33.4 LTBP2 "C14orf141, LTBP3" ENSG00000119681 "Latent transforming growth factor beta binding protein 2" Q14767 14 74498183-74612378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Disease variant, Dwarfism, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 60.6;Fibroblasts: 59.5;Peritubular cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 240.8;HUVEC TERT2: 129.1;LHCN-M2: 129.4;TIME: 564.5" "Group enriched" "Detected in some" 10 "cerebellum: 5.3;olfactory bulb: 2.4" "Region enhanced" "Detected in many" "olfactory bulb: 15.4" HPA003415 Approved Approved Nucleoplasm "Secreted to extracellular matrix" NA NA 14000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003415: AB_1079284" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (5.10e-2)" "unprognostic (3.92e-3)" "unprognostic (2.08e-3)" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (4.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (3.77e-1)" "unprognostic (1.98e-3)" "unprognostic (2.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.94e-4)" 34.2 4.0 1.1 15.2 2.9 0.6 24.4 4.1 5.6 66.2 9.5 6.6 3.1 22.5 23.9 10.7 11.7 33.1 45.4 1.2 1.1 4.1 2.1 64.9 8.3 2.2 1.1 39.4 8.7 9.6 7.3 28.0 1.4 15.7 2.6 2.3 26.7 19.6 13.6 12.6 6.9 16.0 2.2 3.9 8.5 5.4 1.9 3.1 53.0 21.4 6.1 14.2 21.6 1.0 2.5 4.9 1.2 0.2 36.9 67.7 0.2 47.4 16.2 9.2 5.7 0.0 17.4 0.4 13.8 240.8 4.1 4.8 0.2 17.7 3.8 0.2 0.8 0.8 2.2 2.1 8.8 0.1 0.6 70.2 7.7 50.7 29.1 68.9 129.1 0.1 0.2 0.1 129.4 1.1 0.1 0.3 0.3 0.2 4.5 0.5 1.1 0.1 11.3 6.7 1.0 3.3 33.1 0.1 1.1 3.4 1.1 0.2 564.5 3.3 54.0 17.0 18.0 0.7 0.7 0.1 13.1 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 2.9 4.1 5.6 1.2 1.1 2.2 1.1 1.4 2.2 1.9 1.0 3.8 0.0 2.2 2.3 0.1 5.6 15.1 13.0 13.1 2.1 1.9 60.6 6.4 0.0 6.1 0.0 0.0 0.5 1.2 0.1 5.9 1.4 1.2 0.5 7.9 6.5 0.0 5.7 1.1 0.4 0.3 59.5 1.5 0.9 1.3 1.9 9.3 0.4 4.2 3.3 0.7 0.0 20.3 0.3 5.8 5.8 16.4 3.7 0.0 22.5 0.1 0.4 0.0 1.0 0.3 4.4 0.0 82.4 0.3 10.7 0.0 0.0 0.3 1.0 6.6 3.2 10.8 2.8 3.8 5.2 1.0 1.2 0.9 2.2 0.1 2.1 LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 61.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 293.8;U-87 MG: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" 65.4 80.1 44.0 21.4 46.1 11.2 68.0 42.0 56.1 120.0 42.2 103.7 16.8 130.8 36.7 36.7 112.6 39.9 131.2 37.6 41.4 84.5 48.8 72.2 24.7 57.0 49.0 155.5 70.1 44.7 111.0 25.5 45.4 109.0 8.5 12.8 64.2 56.3 54.6 39.6 55.8 35.7 51.7 58.1 62.0 20.3 46.9 17.6 114.0 31.0 12.1 84.9 88.0 54.0 16.5 65.9 8.7 43.2 60.7 97.0 8.5 64.7 43.6 8.2 5.3 25.3 85.5 2.0 53.6 64.2 20.4 71.9 11.8 12.2 3.7 9.5 26.4 15.9 25.2 26.2 40.3 2.2 13.4 109.9 4.9 12.1 1.5 293.8 31.9 5.2 4.9 12.7 6.0 39.4 10.9 5.9 7.6 14.6 81.2 29.3 1.1 32.1 6.7 5.5 2.9 41.8 17.3 24.9 35.3 3.7 46.0 5.8 107.0 24.8 32.2 42.5 17.6 13.9 27.1 1.4 157.8 2.6 52.3 0.2 7.3 2.9 8.8 11.2 14.1 61.2 12.6 10.4 8.9 47.6 10.5 11.2 2.9 10.8 13.2 17.8 14.2 7.8 44.0 46.1 42.0 56.1 37.6 41.4 57.0 49.0 45.4 51.7 46.9 54.0 47.1 12.8 11.7 64.0 26.8 73.8 27.7 22.0 50.7 55.7 42.2 43.1 16.7 35.8 16.2 40.5 2.1 24.7 24.4 19.7 21.5 28.1 1.1 19.3 37.5 29.8 30.6 11.2 21.3 12.0 10.5 86.1 14.8 25.3 24.1 92.5 37.5 61.6 20.7 28.6 17.9 15.1 8.2 11.0 34.4 4.3 86.6 14.6 30.2 17.8 11.5 71.4 24.7 29.7 20.2 18.1 15.0 123.8 20.9 35.8 25.3 15.7 8.2 14.3 39.5 89.4 44.0 9.5 37.5 46.9 79.3 16.3 24.4 26.0 20.4 26.5 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LTF HLF2 ENSG00000012223 Lactotransferrin P02788 3 46435645-46485234 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Ion transport, Iron transport, Osteogenesis, Transcription, Transcription regulation, Transport" "Antibiotic, Antimicrobial, DNA-binding, Heparin-binding, Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 4255.5;salivary gland: 1162.5" "Cell type enriched" "Detected in many" 5 "Breast glandular cells: 1519.6" "Group enriched" "Detected in all" 5 "breast cancer: 239.0;endometrial cancer: 170.3;glioma: 152.6;prostate cancer: 195.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "neutrophil: 5.4;non-classical monocyte: 17.0" "Group enriched" "Detected in many" 23 "granulocytes: 5.4;monocytes: 17.0" "Group enriched" "Detected in some" 11 "RPMI-8226: 43.2;TIME: 14.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB008646, CAB016201, HPA057177, HPA059976" Enhanced "Secreted to blood" NA NA 350000000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "CAB008646: AB_1618695, CAB016201: AB_629860, HPA057177: AB_2683361, HPA059976: AB_2684185" "unprognostic (7.24e-3)" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (3.41e-2)" "unprognostic (7.14e-3)" "unprognostic (3.45e-2)" "unprognostic (6.43e-3)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (3.43e-1)" "unprognostic (1.04e-1)" "prognostic favorable (6.30e-5)" "unprognostic (1.66e-2)" "unprognostic (3.53e-1)" "unprognostic (2.05e-1)" "unprognostic (9.09e-3)" 6.9 1.2 2.5 36.1 3.4 4255.5 333.3 4.6 4.2 658.3 2.2 2.8 1.2 4.1 157.5 23.0 4.3 7.5 5.7 3.7 6.2 105.3 3.3 29.4 8.6 4.8 21.5 0.5 18.6 6.2 7.0 3.1 12.6 154.2 2.2 0.9 1162.5 378.9 1.7 11.8 5.1 1.9 7.1 70.5 331.6 0.4 14.5 29.8 10.1 1.6 345.7 2.4 1.2 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.9 0.5 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.6 43.2 0.2 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 14.3 0.0 0.3 1.2 0.1 0.6 0.0 0.1 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 17.0 0.4 0.0 29.5 2.5 3.4 4.6 4.2 3.7 6.2 4.8 21.5 12.6 7.1 14.5 9.9 15.5 0.0 2.8 0.7 4.3 1.1 8.6 82.8 0.0 0.0 1519.6 198.4 1.0 2.8 298.0 71.7 0.0 0.0 6.2 0.1 0.0 1.4 1.2 0.3 0.2 8.8 0.0 3.0 0.1 0.9 0.2 2.5 56.1 2.3 1.3 0.1 5.0 0.0 0.0 0.0 0.0 0.2 14.2 0.0 0.7 1.5 5.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.1 78.6 0.0 18.6 14.9 0.0 0.0 0.3 9.9 0.2 0.1 15.4 0.1 0.1 4.0 0.1 0.1 101.7 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LUZP2 ENSG00000187398 "Leucine zipper protein 2" Q86TE4 11 24496970-25082638 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 30.6" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 1890.0" "Group enriched" "Detected in some" 7 "glioma: 3.5;prostate cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.9;HAP1: 4.4;HeLa: 1.9;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039007, HPA046161" Enhanced Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039007: AB_2676307, HPA046161: AB_2679564" "unprognostic (4.49e-2)" "unprognostic (2.74e-2)" "unprognostic (8.63e-2)" "unprognostic (3.50e-1)" "unprognostic (5.22e-3)" "unprognostic (3.38e-1)" "unprognostic (4.88e-2)" "unprognostic (5.67e-4)" "unprognostic (2.40e-1)" "unprognostic (5.66e-2)" "unprognostic (6.16e-3)" "unprognostic (4.09e-2)" "unprognostic (5.18e-3)" "unprognostic (9.41e-3)" "unprognostic (4.18e-2)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" 0.3 6.5 8.6 0.1 8.5 0.1 0.5 11.8 8.0 0.1 1.1 0.8 0.1 0.2 0.0 0.1 0.0 0.1 0.1 6.3 15.1 0.2 0.9 0.2 0.0 10.8 30.6 0.0 0.0 0.0 0.6 0.0 17.2 2.4 0.6 1.1 0.1 0.1 0.0 0.1 0.2 0.3 17.6 0.1 0.1 0.5 15.3 0.0 0.0 0.6 0.0 0.3 0.1 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.9 4.4 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 11.8 8.0 6.3 15.1 10.8 30.6 17.2 17.6 15.3 16.5 0.3 0.0 0.0 11.4 0.0 0.6 0.1 0.0 1.8 6.9 0.3 1.7 0.6 0.0 0.0 3.7 0.0 0.0 0.1 1.2 0.0 0.0 33.7 0.6 0.7 0.1 0.0 0.0 149.4 0.0 0.1 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 371.4 1.7 0.0 0.0 0.0 6.4 0.9 0.1 0.0 4.7 0.0 0.3 0.0 1890.0 9.1 0.2 23.9 0.0 0.0 4.5 0.0 0.7 0.0 0.8 0.0 0.4 0.3 0.3 0.6 0.9 0.3 0.1 0.0 2.4 1.5 1.6 LY6G5B "C6orf19, G5b" ENSG00000240053 "Lymphocyte antigen 6 family member G5B" Q8NDX9 6 31670167-31673776 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA048307 Approved "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA048307: AB_2680348" "unprognostic (2.69e-2)" "unprognostic (1.52e-1)" "unprognostic (8.53e-2)" "unprognostic (1.44e-2)" "unprognostic (5.80e-2)" "unprognostic (9.85e-3)" "unprognostic (5.04e-3)" "unprognostic (8.34e-3)" "unprognostic (5.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-4)" "unprognostic (7.27e-3)" "unprognostic (1.98e-5)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (3.00e-2)" "unprognostic (3.98e-4)" 30.1 13.5 3.0 9.5 3.4 29.9 25.9 7.4 7.2 26.3 3.1 25.6 6.9 24.9 11.1 15.8 25.0 6.3 15.0 3.2 3.9 15.5 15.0 27.8 12.1 3.5 3.3 33.2 14.5 2.8 20.8 8.2 3.6 22.1 11.4 11.3 20.3 7.4 15.4 44.6 27.8 9.4 2.7 30.6 19.2 13.0 3.8 7.7 24.7 3.3 13.1 21.1 20.4 3.7 5.4 5.8 11.4 15.5 2.6 5.5 14.5 10.4 3.3 7.3 7.2 7.1 6.8 12.9 2.8 13.0 4.7 8.6 2.7 13.7 11.6 5.2 18.0 12.4 8.1 5.7 2.2 15.6 9.9 11.8 7.9 10.7 5.0 10.3 3.9 9.7 7.7 7.8 5.0 4.9 8.4 12.0 6.4 1.5 2.6 11.8 3.5 5.7 3.4 14.7 8.0 12.9 4.7 1.8 3.6 13.9 4.7 10.3 7.6 14.2 7.5 6.6 2.6 13.6 10.1 11.5 5.1 14.6 4.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.4 7.4 7.2 3.2 3.9 3.5 3.3 3.6 2.7 3.8 3.7 0.3 3.2 0.0 0.0 1.4 1.0 1.2 0.7 0.0 1.1 0.7 0.3 0.1 1.5 0.2 0.0 0.0 0.4 0.8 0.6 0.0 0.1 0.0 0.4 0.8 0.5 1.2 0.0 0.5 0.2 0.4 0.9 1.1 1.1 0.0 1.2 0.4 0.4 0.5 0.0 0.6 0.9 0.0 0.0 2.2 0.0 0.6 0.7 0.0 0.0 0.4 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.6 1.1 1.8 0.0 0.1 2.3 0.0 1.5 0.8 0.1 0.3 0.4 1.3 0.5 1.4 0.4 1.0 0.8 LY6G5C "C6orf20, G5c, NG33" ENSG00000204428 "Lymphocyte antigen 6 family member G5C" Q5SRR4 6 31676684-31684040 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 1.7" "Cell type enhanced" "Detected in many" "Early spermatids: 21.4;Respiratory ciliated cells: 16.1;Spermatocytes: 15.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA038690 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 71: Testis - DNA repair" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA038690: AB_10673286" "unprognostic (1.51e-2)" "unprognostic (7.26e-2)" "unprognostic (7.19e-2)" "prognostic favorable (1.07e-4)" "unprognostic (4.83e-1)" "unprognostic (6.91e-2)" "unprognostic (1.33e-1)" "unprognostic (1.57e-2)" "unprognostic (4.27e-2)" "unprognostic (5.63e-2)" "unprognostic (3.74e-5)" "unprognostic (5.84e-2)" "unprognostic (3.78e-4)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.88e-2)" "unprognostic (1.39e-2)" 0.3 0.2 0.0 0.6 0.4 0.3 0.2 0.2 1.0 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.5 0.5 0.3 0.0 0.0 0.5 0.3 0.5 0.3 0.0 0.0 0.2 0.6 0.0 0.9 0.1 0.3 0.4 0.0 0.6 0.1 0.0 0.8 0.2 0.3 0.0 0.0 0.6 0.3 1.7 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.6 0.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 0.4 0.3 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.4 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 7.8 3.2 1.5 0.3 1.4 1.7 1.8 2.0 0.0 2.8 7.7 8.0 1.2 1.5 2.1 1.8 2.1 0.5 4.2 3.8 3.9 2.1 21.4 6.9 1.4 5.6 3.5 3.0 0.8 4.9 0.2 1.6 3.1 1.8 5.1 1.4 10.4 2.2 6.2 0.0 1.2 2.0 8.2 5.5 3.1 7.5 1.2 11.6 1.8 0.0 3.7 6.0 2.1 1.0 0.6 3.4 3.1 1.5 3.2 2.1 3.0 4.6 16.1 1.1 0.0 2.6 1.7 15.9 13.9 2.0 0.9 0.3 5.2 1.3 3.1 1.9 LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.5;testis: 36.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 186.7;Prostatic glandular cells: 105.2;Spermatocytes: 404.4;Spermatogonia: 105.8;Urothelial cells: 131.4" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.8" "Cell line enhanced" "Detected in many" "A-431: 125.2;BJ: 131.9;HeLa: 142.4;SiHa: 206.3;U-2197: 273.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" 5.4 0.2 0.6 0.2 0.6 0.3 4.4 0.9 1.7 3.3 0.0 0.5 0.3 0.5 0.2 12.5 1.2 0.4 1.5 0.8 1.0 3.0 0.2 0.8 0.2 1.7 0.8 0.7 0.3 0.0 0.4 2.4 2.0 1.1 0.0 2.4 1.7 0.8 5.4 6.8 0.3 0.1 1.1 0.2 1.1 36.0 0.7 0.6 1.0 1.3 0.6 1.0 5.1 1.1 125.2 2.0 0.0 6.3 2.4 7.9 1.5 131.9 15.3 39.9 24.0 0.2 0.5 0.0 10.9 15.0 14.3 10.8 0.0 7.5 33.5 1.2 0.2 0.1 142.4 0.3 1.9 0.0 0.0 11.7 21.1 29.7 38.0 0.1 3.7 0.0 0.0 0.6 76.2 1.0 0.2 0.3 4.2 4.1 2.0 0.3 0.5 0.2 6.7 1.7 3.7 0.5 206.3 2.7 41.3 6.6 0.5 0.2 5.4 1.9 11.8 273.2 0.2 0.2 0.1 0.3 0.6 0.1 13.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.6 0.6 0.9 1.7 0.8 1.0 1.7 0.8 2.0 1.1 0.7 1.1 25.6 3.2 0.5 0.0 0.4 38.9 54.2 4.3 21.6 0.6 15.1 49.8 0.2 5.7 9.8 25.8 0.0 13.5 0.3 0.0 0.0 0.8 7.7 3.1 8.5 9.2 0.0 0.0 0.0 0.0 186.7 8.0 0.0 9.0 0.0 0.0 3.3 0.1 6.0 0.0 0.0 0.0 6.1 0.3 28.7 14.8 4.1 4.6 12.4 0.0 0.0 0.5 0.0 0.0 0.1 6.7 1.1 3.0 0.0 105.2 0.0 0.2 3.6 0.6 0.0 17.8 13.1 404.4 105.8 32.2 44.9 25.3 0.7 0.1 0.0 131.4 LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 78.4" "Group enriched" "Detected in many" 9 "B-cells: 124.9;Hofbauer cells: 191.7;Kupffer cells: 199.1;Langerhans cells: 118.6;Macrophages: 149.8;Microglial cells: 105.9;monocytes: 155.6" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 426.6;myeloid DC: 426.1" "Group enriched" "Detected in all" 43 "B-cells: 335.1;dendritic cells: 426.1;monocytes: 426.6" "Cell line enhanced" "Detected in some" "Daudi: 69.5;NB-4: 44.7;RPMI-8226: 245.0;THP-1: 103.8;U-937: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" NA NA 77000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" 9.7 10.3 14.0 30.9 13.5 29.2 7.4 14.7 22.0 8.2 14.2 7.6 4.9 3.8 2.8 3.1 4.3 14.6 2.9 13.5 15.8 3.1 13.3 29.7 72.1 17.8 15.4 3.3 3.0 3.4 2.3 14.5 18.7 3.8 11.1 1.2 5.5 6.2 0.7 3.4 16.8 11.1 17.8 52.7 6.2 1.8 18.0 15.1 1.5 1.1 78.4 15.6 1.1 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 44.7 0.0 0.0 0.0 8.0 0.0 245.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 103.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 30.3 0.0 45.8 0.0 4.1 426.6 3.5 1.0 234.9 0.7 335.1 1.1 1.1 426.1 248.8 4.7 2.7 9.1 5.3 88.3 16.3 1.8 221.1 14.0 13.5 14.7 22.0 13.5 15.8 17.8 15.4 18.7 17.8 18.0 24.8 1.2 0.0 15.0 1.6 124.9 2.0 0.0 0.0 0.0 0.0 0.9 3.7 1.5 1.5 1.3 0.0 0.0 1.4 9.8 0.0 0.0 0.0 3.4 0.4 0.1 5.4 0.0 3.8 3.8 0.0 1.8 2.1 0.0 0.0 1.3 0.0 4.2 1.3 191.7 0.0 0.6 0.3 0.0 199.1 118.6 15.4 0.3 149.8 0.0 105.9 155.6 0.0 4.1 0.5 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.7 0.4 6.6 0.4 0.2 5.3 0.2 0.3 2.4 1.9 3.6 0.0 0.2 0.2 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 LYG1 SALW1939 ENSG00000144214 "Lysozyme g1" Q8N1E2 2 99284238-99304742 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.5" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 161.4" "Cancer enriched" "Detected in many" 15 "renal cancer: 31.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.53e-2)" "unprognostic (3.13e-2)" "unprognostic (1.53e-2)" "unprognostic (3.73e-1)" "unprognostic (9.74e-2)" "unprognostic (3.76e-4)" "unprognostic (6.94e-4)" "unprognostic (2.58e-2)" "unprognostic (4.72e-2)" "unprognostic (9.74e-3)" "unprognostic (5.01e-2)" "unprognostic (1.06e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.31e-1)" "unprognostic (2.58e-1)" "unprognostic (1.07e-1)" "unprognostic (2.31e-3)" 1.9 1.6 3.1 1.2 3.3 0.9 2.1 6.0 4.3 3.6 1.8 2.3 1.2 2.3 1.8 1.3 2.3 0.8 2.0 3.0 2.6 23.5 5.8 1.9 1.6 3.2 2.8 2.4 1.6 0.2 2.0 0.7 3.2 3.3 1.1 2.6 1.7 0.7 2.1 1.7 2.8 0.9 2.6 4.7 1.7 5.5 3.1 2.4 2.6 0.4 1.3 2.5 2.3 4.1 0.3 2.3 1.7 2.8 3.9 2.2 1.9 0.9 1.0 0.9 1.5 0.4 2.0 0.5 1.5 0.4 0.2 1.0 2.3 0.3 1.1 1.6 1.4 1.3 2.0 0.7 0.7 0.4 3.1 1.8 2.4 1.4 0.6 2.0 0.5 3.0 0.7 1.5 1.0 0.5 1.2 4.0 0.4 1.2 2.1 2.9 1.0 0.8 3.9 0.9 1.0 0.6 0.3 0.7 0.6 2.0 0.3 0.4 1.3 1.2 1.4 2.0 1.0 1.7 1.0 0.3 0.3 2.4 0.5 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.1 3.1 3.3 6.0 4.3 3.0 2.6 3.2 2.8 3.2 2.6 3.1 4.1 0.6 0.0 0.0 3.6 1.5 0.0 0.2 0.6 0.0 1.0 0.8 0.8 0.5 1.5 1.5 1.8 2.1 0.3 0.5 0.5 21.5 0.7 10.8 0.2 0.3 0.5 0.0 0.0 4.6 0.2 0.2 0.4 0.0 0.2 4.5 0.8 1.1 0.5 0.3 0.0 4.2 0.3 0.0 0.3 0.3 4.8 0.3 1.4 0.0 2.8 0.8 0.2 0.0 2.0 5.6 0.6 0.1 0.4 0.0 0.6 0.2 161.4 0.2 0.6 0.0 0.1 0.5 2.4 1.1 0.0 0.0 0.5 0.6 0.3 0.4 0.2 LYG2 LYGH ENSG00000185674 "Lysozyme g2" Q86SG7 2 99242246-99255282 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8;retina: 3.5;skin 1: 8.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.7;Cone photoreceptor cells: 14.6;Excitatory neurons: 19.6;Horizontal cells: 15.2;Inhibitory neurons: 17.5;Rod photoreceptor cells: 29.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enriched" "Detected in some" 4 "cerebellum: 4.8" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "THP-1: 1.7;U-937: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039179 Uncertain "Secreted in other tissues" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA039179: AB_10794633" "unprognostic (5.12e-2)" "unprognostic (8.70e-3)" "unprognostic (6.29e-2)" "unprognostic (3.91e-2)" "unprognostic (1.47e-1)" "unprognostic (7.29e-2)" "unprognostic (1.86e-2)" "unprognostic (1.78e-2)" "unprognostic (1.90e-1)" "unprognostic (1.30e-2)" "unprognostic (1.30e-5)" "unprognostic (1.40e-3)" "unprognostic (1.08e-13)" "unprognostic (9.98e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-2)" "unprognostic (9.24e-3)" 0.2 0.1 0.4 0.1 0.5 0.5 0.0 4.8 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 3.5 0.3 0.0 0.3 8.8 0.1 0.0 0.0 0.2 0.2 1.4 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 0.4 0.4 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.3 0.9 0.2 0.0 1.0 0.2 0.0 0.0 0.1 0.4 0.1 0.2 0.6 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 1.0 0.2 0.6 0.3 0.0 1.2 0.2 0.6 0.4 1.1 0.3 0.5 0.1 0.0 0.0 0.0 0.4 0.3 1.7 0.6 0.6 0.4 0.1 0.4 0.2 0.8 0.1 0.3 2.5 0.4 0.0 0.2 0.1 0.3 0.0 0.2 0.6 0.8 0.4 0.0 1.1 0.3 0.3 0.1 0.2 0.0 0.9 0.1 0.0 0.4 0.5 4.8 1.0 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.9 0.0 0.0 5.5 1.2 0.6 0.5 0.3 0.0 13.7 0.8 0.9 0.3 5.7 0.1 0.0 14.6 0.9 1.6 0.1 0.0 0.1 6.1 0.6 0.9 0.7 0.0 0.0 19.6 0.0 0.2 0.8 0.0 0.3 0.0 0.5 1.1 0.0 0.2 15.2 17.5 0.0 0.0 0.9 0.3 2.2 0.0 0.2 1.8 0.0 0.2 6.9 4.1 7.5 8.9 0.1 0.0 0.7 0.0 0.7 0.3 0.3 0.0 29.9 0.0 2.0 0.9 1.8 1.6 0.0 0.4 0.3 0.9 0.2 0.4 0.1 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 LYPD8 ENSG00000259823 "LY6/PLAUR domain containing 8" Q6UX82 1 248739415-248755759 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 215.9" "Group enriched" "Detected in some" 5 "Distal enterocytes: 710.5;Paneth cells: 1098.0" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 15.2" "Group enriched" "Detected in many" 10 "amygdala: 1.1;basal ganglia: 1.6;cerebral cortex: 1.9;hippocampal formation: 1.1;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (6.69e-3)" "unprognostic (3.53e-2)" "unprognostic (1.08e-5)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-4)" "unprognostic (8.62e-2)" "unprognostic (7.28e-2)" "unprognostic (3.22e-1)" "unprognostic (9.73e-2)" "unprognostic (1.87e-1)" "unprognostic (1.19e-4)" "unprognostic (2.57e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" 0.1 0.0 1.1 11.4 1.6 0.5 0.6 0.0 1.9 0.0 0.0 215.9 0.7 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 126.8 0.0 0.0 0.4 0.0 0.0 26.4 3.5 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 1.1 1.6 0.0 1.9 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 710.5 1.9 0.0 4.7 0.0 0.0 0.0 31.5 0.0 15.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 166.9 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 1098.0 0.0 0.0 0.1 38.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.3 0.3 0.0 16.6 0.0 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 LYZL1 "LYC2, MGC33408" ENSG00000120563 "Lysozyme like 1" Q6UWQ5 10 29289061-29318328 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 429 "testis: 51.0" "Group enriched" "Detected in some" 37 "Early spermatids: 600.3;Late spermatids: 201.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.88e-1)" "unprognostic (8.40e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 600.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 201.8 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.0 10.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYZL2 ENSG00000151033 "Lysozyme like 2" Q7Z4W2 10 30611779-30629762 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 712 "testis: 71.1" "Group enriched" "Detected in some" 43 "Early spermatids: 786.1;Late spermatids: 204.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-BR-3: 3.0" "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.83e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 786.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 204.1 7.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.3 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYZL4 "LYC4, MGC26768" ENSG00000157093 "Lysozyme like 4" Q96KX0 3 42397083-42410610 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "testis: 52.1" "Group enriched" "Detected in some" 46 "Early spermatids: 386.3;Late spermatids: 158.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "OE19: 3.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA038806 Approved "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA038806: AB_10674841" "unprognostic (4.03e-1)" "unprognostic (5.68e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 386.3 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 158.8 3.1 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.9 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYZL6 "LYC1, PRO1485, TKAL754" ENSG00000275722 "Lysozyme like 6" O75951 17 35934518-35943713 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 132 "testis: 47.9" "Cell type enriched" "Detected in some" 6 "Early spermatids: 387.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025734, HPA053073" Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA025734: AB_1853444, HPA053073: AB_2682034" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 47.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 387.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.3 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 15.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 74.5" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 37.0;Fibroblasts: 38.7;Inhibitory neurons: 42.9;Leydig cells: 96.6;Microglial cells: 45.9;Peritubular cells: 82.0;Sertoli cells: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.7;HHSteC: 57.2;LHCN-M2: 75.0;TIME: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" 17.2 8.2 1.0 1.2 1.2 0.2 15.6 0.8 1.6 30.4 2.3 45.5 8.4 74.5 19.1 21.2 58.5 13.0 15.4 0.7 1.5 2.6 1.2 37.2 0.5 0.7 1.2 49.1 3.7 1.8 0.8 4.3 0.7 7.7 12.3 5.7 9.9 10.8 6.6 9.2 21.6 25.3 0.7 16.1 19.1 7.5 1.8 1.6 8.0 17.1 3.1 32.3 18.5 1.1 0.3 0.0 0.7 0.0 55.7 18.8 1.7 11.1 5.0 2.7 4.6 0.0 1.2 0.0 0.7 2.1 1.5 9.1 0.1 0.8 2.3 0.0 0.0 0.0 15.6 0.1 57.2 0.0 0.0 3.6 0.7 1.7 0.9 19.9 4.9 0.0 0.0 0.5 75.0 0.0 0.0 0.1 7.7 0.1 0.0 0.0 8.8 7.3 24.6 0.0 0.7 0.0 0.1 0.1 0.0 20.8 0.0 0.0 71.0 0.0 1.8 0.1 2.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.6 0.7 1.5 0.7 1.2 0.7 0.7 1.8 1.1 2.0 0.0 1.5 20.2 0.5 6.1 0.5 0.4 0.6 0.8 0.5 10.8 4.3 0.0 0.1 3.7 4.2 0.2 0.2 0.2 0.0 0.1 42.5 0.7 13.7 3.9 0.0 0.0 37.0 0.2 6.6 38.7 0.5 0.5 1.3 0.3 0.4 0.0 3.3 0.0 42.9 0.1 0.0 0.0 17.5 11.4 96.6 13.6 10.6 45.9 0.0 13.8 0.0 11.6 23.3 0.4 0.2 82.0 0.0 0.1 0.0 0.5 0.1 0.5 39.5 4.8 22.4 0.4 0.4 1.1 4.8 0.3 0.8 0.1 0.1 0.1 MAN2B2 KIAA0935 ENSG00000013288 "Mannosidase alpha class 2B member 2" Q9Y2E5 4 6575189-6623362 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 15000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "unprognostic (1.30e-1)" "unprognostic (3.32e-1)" "unprognostic (1.28e-1)" "prognostic favorable (7.59e-4)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "unprognostic (6.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-3)" "unprognostic (2.18e-1)" 20.0 13.6 12.9 13.8 18.2 14.8 16.4 7.7 14.3 17.6 26.0 14.5 13.4 18.6 14.1 11.3 17.7 15.9 22.6 13.2 15.6 15.1 23.7 18.2 13.5 13.0 13.2 26.6 22.0 9.2 17.9 12.9 11.8 18.0 7.9 5.2 16.7 11.5 4.7 13.6 15.8 10.3 10.6 17.7 20.1 4.4 15.0 9.0 23.2 4.7 8.5 19.3 15.9 11.9 17.5 15.6 2.9 21.0 44.7 30.9 19.7 35.0 40.5 16.8 22.9 9.0 32.3 8.7 16.5 38.2 39.2 17.4 1.0 11.1 9.2 10.4 8.8 11.7 10.9 10.2 19.5 22.0 51.8 41.0 10.9 13.4 3.6 30.3 19.7 10.8 5.1 21.9 22.1 10.8 10.9 13.9 3.8 21.8 11.9 10.7 14.4 10.4 8.8 17.4 5.0 5.5 23.4 13.9 8.9 10.0 27.7 29.1 36.3 30.3 9.1 38.2 22.5 9.0 8.4 4.2 35.4 25.5 26.7 15.4 9.0 14.3 11.7 13.2 8.9 4.2 7.0 10.7 8.6 4.4 6.3 8.2 11.0 6.8 17.5 3.3 10.7 11.0 12.9 18.2 7.7 14.3 13.2 15.6 13.0 13.2 11.8 10.6 15.0 11.9 9.8 16.0 18.9 7.8 11.6 5.0 5.5 4.9 11.4 8.9 8.2 5.6 17.0 20.0 11.1 11.0 6.2 13.5 12.9 18.3 1.9 9.7 0.6 18.7 15.8 8.2 7.8 5.7 9.4 10.7 10.2 18.4 11.7 36.8 10.8 11.1 17.5 44.1 20.9 10.1 8.3 11.0 2.0 30.2 8.2 1.1 19.6 18.0 3.6 8.4 11.2 13.0 5.2 6.0 8.9 10.1 9.0 24.5 15.1 7.1 11.7 4.2 9.5 7.4 13.1 7.5 8.5 1.1 0.6 8.0 3.8 8.5 15.6 4.4 8.9 4.6 MANF "ARMET, ARP" ENSG00000145050 "Mesencephalic astrocyte derived neurotrophic factor" P55145 3 51385291-51389397 "Plasma proteins, Predicted secreted proteins" "Stress response, Unfolded protein response" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 426.1;Syncytiotrophoblasts: 459.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 109.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011175 Approved Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 7500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA011175: AB_1845039" "unprognostic (2.90e-2)" "unprognostic (5.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.51e-2)" "unprognostic (5.84e-2)" "prognostic unfavorable (9.58e-6)" "prognostic unfavorable (7.48e-4)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.12e-3)" "unprognostic (1.35e-1)" "unprognostic (3.01e-1)" "unprognostic (1.21e-2)" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" "unprognostic (5.10e-2)" 39.4 36.7 34.4 70.9 34.5 35.3 41.8 37.8 50.5 59.4 44.2 55.4 42.5 48.2 169.3 53.2 42.8 32.1 51.1 34.8 42.7 48.6 109.2 44.3 50.5 38.4 35.7 28.7 81.1 38.8 56.4 59.9 37.2 51.3 58.8 17.7 51.0 50.5 12.4 36.6 39.5 47.2 36.2 56.1 59.5 43.2 37.9 47.7 117.8 20.8 76.1 67.8 35.5 38.1 128.6 61.2 164.7 207.7 107.8 139.4 173.8 200.2 160.6 194.0 184.5 99.6 292.6 271.6 162.6 121.9 449.8 77.7 201.4 200.0 187.3 128.9 92.2 220.2 93.5 230.3 349.8 108.2 137.1 60.6 168.5 201.3 271.7 189.9 252.7 112.3 48.3 299.5 181.6 75.5 184.8 215.6 144.6 298.0 237.6 76.4 105.3 288.7 162.8 86.9 64.4 201.6 165.3 104.2 130.3 175.8 83.7 141.2 129.3 117.4 112.1 140.4 222.6 247.9 105.0 186.5 195.4 217.5 221.2 73.2 15.3 9.4 28.8 13.0 35.5 17.4 20.2 27.5 16.0 12.1 14.9 16.0 8.5 26.0 8.3 109.8 13.4 16.9 34.4 34.5 37.8 50.5 34.8 42.7 38.4 35.7 37.2 36.2 37.9 38.1 55.9 32.1 21.5 5.2 134.1 163.1 223.7 232.5 31.3 15.1 50.5 40.5 69.3 61.5 104.0 55.2 6.2 188.1 142.8 75.7 43.0 172.6 99.0 73.3 101.9 88.3 116.6 26.1 5.8 124.6 387.0 101.2 71.9 99.4 62.9 77.9 79.6 156.1 179.5 11.8 8.5 235.9 118.0 36.1 170.6 123.3 60.0 63.0 181.5 7.5 79.1 39.6 117.4 5.0 9.5 167.8 90.5 51.6 426.1 245.0 47.7 78.9 71.1 19.1 65.7 59.7 194.2 176.8 91.1 42.8 160.5 459.0 94.8 40.6 120.9 202.0 MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skeletal muscle: 79.0" "Cell type enhanced" "Detected in many" "Astrocytes: 142.4;Bipolar cells: 314.4;Early spermatids: 199.9;Excitatory neurons: 189.2;Horizontal cells: 361.7;Inhibitory neurons: 153.7;Late spermatids: 416.6;Muller glia cells: 145.7;Oligodendrocytes: 163.8" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "HDLM-2: 69.0;SCLC-21H: 21.1;T-47d: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" NA NA 7100 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" 4.7 4.3 26.2 0.3 27.1 0.0 9.1 8.3 67.7 2.4 0.0 8.4 0.5 1.0 0.2 8.4 1.0 0.8 9.4 30.0 20.4 14.7 0.6 0.8 0.3 11.6 11.4 0.6 1.5 2.9 29.5 3.4 22.4 5.4 0.3 17.6 8.5 3.4 79.0 6.3 1.8 0.3 2.7 0.4 1.7 20.3 14.8 0.4 0.9 27.4 0.2 10.2 2.3 19.7 2.9 0.5 0.3 6.4 0.3 0.9 1.8 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.4 0.5 0.1 2.3 0.3 0.0 69.0 3.4 0.0 0.3 4.2 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.1 0.0 4.4 0.7 3.6 0.0 7.7 1.0 0.2 0.2 0.7 2.0 0.0 4.0 8.5 0.0 9.1 21.1 9.1 2.5 0.0 1.8 1.0 34.7 0.1 0.1 0.3 0.8 1.7 0.3 0.9 0.3 0.0 0.6 2.0 0.5 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.0 0.7 0.0 26.2 27.1 8.3 67.7 30.0 20.4 11.6 11.4 22.4 2.7 14.8 19.7 1.9 0.0 9.8 142.4 1.0 1.0 1.4 0.2 1.2 314.4 26.7 21.2 35.2 0.0 0.1 1.8 64.6 0.2 0.4 0.1 7.9 0.5 199.9 0.4 1.7 1.8 0.0 0.0 189.2 0.4 9.1 3.7 0.5 1.3 4.5 1.6 1.1 0.5 0.3 361.7 153.7 0.0 2.0 0.6 1.7 416.6 2.8 0.8 5.4 8.4 0.7 145.7 0.0 129.7 163.8 0.6 0.0 2.6 0.1 2.5 0.1 76.1 0.0 28.3 0.0 28.2 6.0 18.4 8.1 22.7 3.3 0.3 1.5 0.8 0.3 0.6 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cardiomyocytes: 38.1;Cholangiocytes: 20.0;Endometrial stromal cells: 30.6;Fibroblasts: 16.4;Hepatic stellate cells: 23.2;Hepatocytes: 65.8" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 133.3;BJ hTERT+: 498.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 6.3 3.6 9.4 1.3 9.4 0.0 2.8 12.9 7.0 120.0 4.9 57.5 1.9 88.4 3.3 11.1 17.7 5.1 116.1 10.4 27.0 4.8 183.4 6.0 1.0 19.2 16.5 2.7 0.2 0.3 1.0 9.0 15.3 46.0 5.6 0.0 2.3 52.2 37.5 6.3 7.5 44.4 22.2 0.8 1.6 0.5 14.6 0.2 3.2 18.9 4.3 9.9 61.5 32.0 0.0 0.0 0.3 0.4 15.7 17.3 0.1 133.3 498.3 1.8 0.9 0.0 0.0 0.1 0.0 40.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.2 0.0 0.0 5.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.4 12.9 7.0 10.4 27.0 19.2 16.5 15.3 22.2 14.6 32.0 1.1 0.0 1.8 28.1 0.2 2.9 0.1 0.2 0.0 0.0 0.0 0.0 38.1 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.7 30.6 2.0 0.0 0.0 0.2 0.0 0.3 16.4 0.0 0.7 0.0 0.2 23.2 65.8 0.4 0.0 0.9 0.0 0.0 1.9 3.7 7.5 2.5 0.3 1.8 1.0 0.0 0.0 0.0 10.1 0.2 0.0 0.0 0.7 0.1 0.1 0.0 2.4 0.0 0.0 0.0 5.4 4.5 0.0 0.0 0.2 1.7 0.1 0.5 5.1 0.0 0.1 MASP2 MASP1P1 ENSG00000009724 "Mannan binding lectin serine peptidase 2" O00187 1 11026523-11047239 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "liver: 476.5" "Cell type enriched" "Detected in some" 52 "Hepatocytes: 658.6" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Region enriched" "Detected in single" 9 "cerebellum: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" NA NA 340000000 820000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favorable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" 2.1 1.2 0.0 1.7 0.0 7.4 2.2 6.4 0.7 2.4 0.0 2.7 1.6 2.8 0.0 1.2 2.7 1.2 1.3 0.1 0.0 1.0 476.5 1.8 2.7 0.0 0.0 2.9 2.9 0.0 2.3 0.6 0.2 1.6 0.0 6.9 2.5 0.0 5.1 5.3 3.4 0.0 0.0 2.5 2.4 1.5 0.0 0.0 1.9 0.0 0.0 2.1 1.6 0.4 0.5 0.3 2.6 1.6 0.0 0.1 0.4 0.7 0.0 0.0 0.0 1.2 1.0 2.3 0.6 0.0 0.5 0.7 0.0 0.0 0.0 0.6 2.3 1.3 2.7 16.4 0.0 2.0 1.5 0.0 0.0 0.1 0.0 1.8 0.0 1.7 0.7 0.5 0.0 0.5 0.6 1.1 0.3 0.2 0.7 1.6 0.9 0.6 0.0 1.3 1.7 0.7 0.9 0.4 0.4 1.6 0.6 1.2 1.2 0.9 0.5 0.8 0.5 0.5 0.9 1.5 0.5 1.7 0.4 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 4.6 1.1 0.9 0.2 0.0 0.6 0.2 0.2 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.9 0.0 5.3 9.5 0.0 0.0 0.1 0.0 0.1 1.3 0.0 8.2 658.6 0.1 0.0 8.3 0.0 0.0 12.6 0.3 0.0 0.0 0.0 1.8 1.9 0.0 0.1 0.0 8.0 10.4 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.7 0.4 0.0 0.7 0.2 0.0 0.0 0.4 0.6 0.0 0.8 0.1 0.0 0.1 MATN1 "CMP, CRTM" ENSG00000162510 "Matrilin 1" P21941 1 30711277-30723585 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.3;retina: 5.2" "Cell type enhanced" "Detected in some" "B-cells: 4.1;Paneth cells: 1.1" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 1.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028580 Supported "Secreted to extracellular matrix" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 57: B-cells - Immune response" "HPA028580: AB_10601913" "unprognostic (4.71e-2)" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (3.75e-6)" "unprognostic (9.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.31e-3)" "unprognostic (2.63e-1)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (7.31e-2)" "unprognostic (5.22e-2)" "unprognostic (4.01e-13)" "unprognostic (8.23e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (3.42e-2)" 0.0 0.1 0.4 0.3 0.5 0.7 0.0 0.4 0.4 0.5 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.5 0.6 0.4 0.7 0.2 0.0 0.2 0.3 0.7 0.1 0.0 5.2 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.4 0.1 0.2 0.4 0.0 0.3 0.0 0.0 0.1 0.2 1.3 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.3 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.0 0.7 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.5 0.4 0.4 0.2 0.4 0.6 0.4 0.7 0.3 0.4 1.3 0.3 0.0 0.5 0.0 4.1 0.1 0.6 0.1 0.0 0.0 0.4 1.0 0.5 0.0 0.6 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.4 0.2 0.3 0.2 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 1.1 0.4 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.5 0.2 0.8 0.5 0.5 0.1 0.3 0.5 0.3 0.0 0.1 MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 201.0;Peritubular cells: 258.8;Theca cells: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Cell line enhanced" "Detected in many" "BJ: 72.5;BJ hTERT+ SV40 Large T+: 78.6;BJ hTERT+ SV40 Large T+ RasG12V: 106.7;HaCaT: 114.4;HBF TERT88: 100.6;SuSa: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" 54.4 51.0 24.3 30.2 22.5 1.8 43.6 17.6 23.2 194.4 19.3 67.5 58.5 147.0 101.6 32.8 46.9 40.1 110.2 20.0 23.4 39.3 24.6 15.2 18.0 24.1 30.5 116.4 11.3 28.0 9.9 177.9 26.3 104.9 57.8 45.7 42.6 171.9 4.0 62.8 80.6 98.1 18.3 5.9 23.7 31.2 23.4 4.9 271.4 28.5 15.4 103.0 139.2 30.8 24.1 10.8 23.3 2.5 60.7 3.6 15.0 72.5 17.6 78.6 106.7 13.0 8.4 0.1 7.0 29.2 3.5 114.4 2.3 4.4 100.6 0.0 2.9 0.8 6.1 0.9 14.0 0.0 0.0 13.6 9.5 16.1 0.8 22.1 0.5 1.3 0.1 0.2 4.1 11.2 0.0 0.7 7.1 0.3 3.7 0.0 2.4 11.4 5.7 5.3 16.0 1.5 11.5 0.2 19.8 67.3 10.9 1.4 0.6 5.2 31.5 16.1 11.0 0.9 0.2 0.2 18.8 0.4 5.9 0.0 0.1 0.1 0.2 0.4 5.2 0.0 0.7 0.9 0.8 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 24.3 22.5 17.6 23.2 20.0 23.4 24.1 30.5 26.3 18.3 23.4 30.8 27.8 3.2 1.3 11.1 0.3 37.3 10.1 6.2 80.2 6.3 3.8 45.8 29.1 18.6 3.0 16.5 54.2 1.2 0.2 20.6 0.0 9.9 86.0 4.2 22.6 32.4 23.4 3.2 6.4 0.0 1.1 113.1 5.1 5.0 0.0 43.5 201.0 11.0 1.6 0.0 11.5 25.4 0.0 5.0 7.7 108.6 103.5 0.9 28.4 19.7 2.0 8.1 0.0 86.0 59.8 3.2 18.2 258.8 0.0 6.5 118.7 3.4 1.6 52.9 13.1 97.2 17.1 2.5 2.6 7.3 8.5 2.5 2.0 297.5 27.4 1.8 MATN3 "EDM5, HOA" ENSG00000132031 "Matrilin 3" O15232 2 19992052-20012668 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.2;placenta: 11.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 38.5;Sertoli cells: 26.3" "Cancer enhanced" "Detected in all" "pancreatic cancer: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "Hep G2: 143.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 1.7" HPA051250 Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 440000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum, Golgi apparatus" "HPA051250: AB_2681406" "unprognostic (3.47e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (7.57e-2)" "unprognostic (2.75e-2)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.62e-5)" "unprognostic (1.27e-1)" "unprognostic (4.84e-2)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (2.54e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.51e-1)" "unprognostic (7.04e-2)" "unprognostic (3.15e-2)" 2.2 0.6 5.1 0.5 3.2 0.0 2.7 3.4 5.7 2.5 2.5 0.6 0.4 2.1 0.9 0.5 1.9 2.1 0.4 3.4 3.9 1.9 0.0 13.2 0.3 5.2 6.0 0.7 0.4 0.4 0.3 11.3 5.2 1.6 0.5 0.3 0.6 4.6 0.3 0.8 0.4 1.7 4.7 0.3 1.8 0.9 7.6 0.1 1.3 0.6 0.3 0.8 1.2 3.6 6.4 4.9 16.1 0.1 4.5 9.7 1.0 2.0 1.1 6.5 8.2 4.7 2.7 0.0 0.8 1.7 6.2 1.1 0.4 12.7 9.2 0.0 0.4 0.0 1.1 143.4 1.1 0.0 0.0 21.3 0.7 7.1 1.7 4.5 8.7 0.0 0.0 0.0 13.8 2.5 0.0 0.0 5.0 0.2 2.4 0.0 0.0 0.0 19.5 4.5 0.1 2.1 10.6 1.8 6.5 27.1 19.2 0.1 4.9 9.5 11.4 0.4 1.2 0.1 0.0 0.0 1.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.2 3.4 5.7 3.4 3.9 5.2 6.0 5.2 4.7 7.6 3.6 1.6 38.5 2.2 0.0 0.0 0.3 0.3 2.6 0.0 0.0 5.4 1.3 0.3 0.0 2.3 1.8 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.3 0.8 2.8 0.0 0.0 0.1 0.2 1.9 1.9 0.0 0.5 0.0 4.4 0.0 0.0 0.1 0.0 0.2 0.0 4.1 0.0 0.3 0.4 1.5 0.1 3.6 4.7 0.0 0.0 0.0 0.5 0.2 1.1 0.0 4.5 0.0 0.3 0.0 0.8 1.6 0.0 26.3 0.8 6.8 0.0 1.3 0.0 0.1 0.1 0.1 6.3 0.0 0.2 MATN4 ENSG00000124159 "Matrilin 4" O95460 20 45293445-45308529 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "pancreas: 24.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Fibroblasts: 8.5;Langerhans cells: 6.3;Spermatogonia: 4.9;Suprabasal keratinocytes: 4.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 2.5;U-937: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 14000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.54e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-2)" "unprognostic (8.38e-2)" "unprognostic (9.67e-2)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (6.27e-2)" "unprognostic (6.74e-3)" "unprognostic (5.53e-1)" "unprognostic (6.19e-3)" "unprognostic (3.63e-6)" "unprognostic (2.38e-1)" "unprognostic (4.69e-2)" "unprognostic (4.27e-1)" "unprognostic (5.38e-2)" 0.7 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 24.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 6.4 0.7 1.0 0.0 0.0 1.6 1.9 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.1 0.7 0.2 0.4 0.0 0.0 1.0 2.5 0.0 8.5 1.1 0.8 0.0 0.3 0.4 0.2 0.1 0.0 0.4 0.1 0.0 0.0 6.3 0.5 0.0 0.1 1.8 1.0 0.0 0.0 0.0 3.0 0.4 0.9 0.1 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.4 0.4 1.6 4.9 0.3 4.3 0.3 0.3 0.1 0.2 1.0 MBL2 "COLEC1, MBL" ENSG00000165471 "Mannose binding lectin 2" P11226 10 52765380-52772784 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2810 "liver: 280.9" "Cell type enriched" "Detected in some" 66 "Hepatocytes: 238.5" "Cancer enriched" "Detected in single" 275 "liver cancer: 22.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "Hep G2: 2.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 11 "basal ganglia: 1.1" "HPA002027, CAB016782" Enhanced "Secreted to blood" NA NA 1220000000 1900000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016782: , HPA002027: AB_1079324" "unprognostic (1.72e-2)" "unprognostic (3.03e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 280.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 238.5 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 MDK "FLJ27379, MK, NEGF2" ENSG00000110492 Midkine P21741 11 46380756-46383837 "Cancer-related genes, Predicted secreted proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 529.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 1010.4;Granulosa cells: 726.2;Paneth cells: 1272.7;Proximal enterocytes: 883.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;neutrophil: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 888.4;REH: 1343.8;SH-SY5Y: 1093.6" "CAB010055, HPA057126" Uncertain Approved Vesicles "Secreted to blood" NA NA 158000 960000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB010055: AB_627949, HPA057126: AB_2683344" "unprognostic (8.87e-3)" "unprognostic (6.65e-2)" "unprognostic (4.02e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.11e-2)" "unprognostic (4.01e-2)" "unprognostic (4.15e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (8.78e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" 41.1 98.0 23.3 22.9 23.3 11.7 82.2 27.0 37.0 379.4 16.3 78.0 263.3 208.2 60.3 38.1 170.3 140.0 36.1 21.6 40.7 35.9 8.5 48.5 20.3 31.8 27.5 529.1 30.5 103.9 370.4 32.0 22.6 128.7 38.0 5.9 137.4 84.1 7.6 26.9 211.3 49.5 24.6 78.1 108.3 16.8 31.5 92.9 26.8 9.8 15.9 84.1 129.3 24.6 51.1 66.5 758.4 2.5 5.2 62.2 18.6 39.2 77.0 145.6 128.8 505.2 219.5 3.4 528.6 58.5 6.3 429.6 431.8 0.7 13.3 157.0 91.6 22.5 5.6 703.6 336.2 1.7 3.5 100.0 13.2 89.2 0.5 31.0 214.3 28.9 385.2 3.5 83.3 348.6 19.8 9.4 888.4 275.9 388.0 1343.8 28.8 4.4 1.8 1.6 418.1 1093.6 128.9 11.3 11.0 665.8 347.3 349.5 59.0 221.1 526.2 3.1 27.2 2.9 11.0 5.1 6.5 13.7 197.3 0.0 0.0 0.0 0.1 0.2 0.0 1.8 0.1 0.2 0.0 0.4 0.0 0.0 2.1 0.1 0.2 0.1 0.9 0.4 23.3 23.3 27.0 37.0 21.6 40.7 31.8 27.5 22.6 24.6 31.5 24.6 108.2 0.0 5.4 5.5 9.6 11.1 162.1 392.4 12.5 1.3 245.2 218.7 7.0 34.3 393.6 47.8 0.0 162.3 5.4 499.0 1.9 286.0 26.4 134.6 490.2 115.0 1010.4 2.5 2.1 104.5 123.5 275.2 162.1 228.2 4.5 726.2 102.4 4.6 48.3 0.0 1.9 368.8 286.8 4.2 12.0 126.3 109.6 10.0 37.4 7.5 9.4 47.1 0.0 4.5 1.3 221.1 1272.7 18.8 18.6 163.6 883.4 19.6 109.5 1.1 85.5 26.1 197.0 31.8 34.3 26.2 8.1 153.1 11.4 8.9 187.6 511.1 MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 20.6;Basal keratinocytes: 18.4;Basal squamous epithelial cells: 23.3;Melanocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 51.1;HeLa: 56.3;hTERT-RPE1: 69.7;U-2197: 55.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" Yes No 1700000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" 25.9 4.3 2.9 3.9 2.7 10.8 20.0 2.6 2.8 14.5 1.4 14.1 2.1 9.6 1.4 13.2 28.9 11.2 14.2 1.9 3.2 5.9 5.0 22.1 5.5 3.5 5.8 18.0 6.5 0.4 4.1 2.8 3.6 26.5 1.1 1.8 19.3 4.7 4.8 44.6 10.0 1.4 2.1 10.7 10.1 3.3 3.7 3.4 11.6 1.9 3.4 11.0 22.8 1.9 11.6 14.1 4.3 6.6 0.4 0.3 1.0 51.1 14.1 5.2 1.6 3.3 10.4 0.0 13.8 24.6 4.4 6.7 0.0 0.5 1.7 0.0 0.4 0.0 56.3 3.3 0.0 0.2 0.9 0.1 0.6 0.4 0.8 69.7 5.6 0.1 0.0 0.0 0.1 6.0 0.0 10.9 2.7 3.3 0.9 2.2 3.0 6.2 1.1 3.8 3.8 3.1 18.8 1.1 6.4 11.4 4.9 1.5 2.2 19.6 1.7 55.6 3.9 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.8 0.0 0.0 0.0 0.8 0.1 2.9 2.7 2.6 2.8 1.9 3.2 3.5 5.8 3.6 2.1 3.7 1.9 5.0 22.4 20.6 8.8 2.7 18.4 7.1 3.9 23.3 0.8 3.6 3.0 3.3 5.7 4.4 1.8 0.0 0.2 0.4 0.6 0.0 3.6 0.2 1.4 0.6 7.0 0.0 4.8 6.5 1.4 1.3 9.4 6.6 5.0 1.3 9.8 16.8 0.9 1.0 0.0 7.2 1.4 0.0 0.3 7.5 0.5 11.5 2.8 19.6 5.6 0.7 14.7 1.0 4.5 5.2 4.5 0.1 3.4 0.4 4.0 0.5 1.2 0.3 1.2 0.0 0.5 2.7 0.3 1.1 7.6 11.4 0.4 3.6 0.1 1.1 2.7 MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "intestine: 363.9" "Cell type enriched" "Detected in some" 42 "Proximal enterocytes: 231.8" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA029119 Enhanced "Secreted to digestive system" NA NA 310000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 45: Enterocytes - Digestion" "HPA029119: AB_2672913" "unprognostic (1.33e-1)" "unprognostic (6.72e-2)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "unprognostic (3.50e-4)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (4.30e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-4)" "unprognostic (4.74e-2)" "unprognostic (3.39e-1)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (3.75e-2)" 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.3 0.0 0.0 8.2 249.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 6.5 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 363.9 0.3 0.1 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 4.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.3 0.3 0.1 0.2 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.4 0.0 0.0 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.9 0.0 3.8 0.0 0.1 0.2 231.8 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 2.5 0.1 MEPE ENSG00000152595 "Matrix extracellular phosphoglycoprotein" Q9NQ76 4 87821411-87846817 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 107 "brain: 10.6" "Cell type enriched" "Detected in single" 18 "Inhibitory neurons: 12.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038003, HPA038004" Uncertain "Secreted to extracellular matrix" NA NA 810000 "Cluster 10: Brain - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA038003: AB_2675780, HPA038004: AB_10670537" "unprognostic (2.88e-1)" "unprognostic (8.15e-2)" "unprognostic (3.62e-1)" "unprognostic (1.91e-1)" "unprognostic (1.61e-1)" "unprognostic (4.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.41e-1)" "unprognostic (5.64e-4)" 0.0 0.0 4.6 0.0 1.1 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 4.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.1 0.0 10.6 0.9 4.0 0.3 0.0 0.9 0.2 0.1 2.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 203.8;CAPAN-2: 219.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 100000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 10.3 0.8 0.1 3.4 0.6 7.4 8.9 0.1 7.5 13.1 9.6 9.7 6.5 6.4 2.5 6.1 4.7 11.9 6.2 6.6 0.8 20.1 42.9 20.3 2.3 1.1 2.5 0.8 6.6 0.8 3.8 26.4 4.9 6.7 9.3 3.9 8.7 11.2 14.3 7.7 8.2 5.7 0.3 6.0 15.4 0.5 0.5 3.7 17.6 11.0 3.2 18.4 4.4 7.8 203.8 115.3 0.1 0.6 8.6 8.7 7.9 113.7 48.2 60.3 51.1 25.0 219.0 8.4 179.0 72.1 163.3 51.8 19.7 110.0 123.7 0.3 23.4 0.1 112.5 21.4 1.5 0.3 0.2 11.4 42.4 40.6 129.1 109.4 42.4 0.2 4.5 0.8 114.1 5.0 0.1 0.1 17.3 32.9 113.0 0.2 95.3 0.2 105.8 24.0 16.5 0.0 45.4 15.4 44.9 19.8 0.4 0.9 72.3 89.7 30.6 46.7 88.9 2.5 19.1 1.5 99.3 0.3 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 7.5 6.6 0.8 1.1 2.5 4.9 0.3 0.5 7.8 32.6 28.9 103.6 0.3 1.0 39.0 70.5 58.1 38.1 6.7 6.5 6.9 12.3 11.5 99.8 31.3 0.0 76.0 0.4 20.5 0.0 38.5 0.0 52.5 11.6 20.1 7.2 0.0 2.6 46.9 7.5 7.4 32.6 161.4 0.0 0.0 3.9 30.5 7.0 0.0 1.0 20.5 18.3 1.3 2.2 0.1 0.6 4.4 3.6 1.9 1.0 7.6 0.0 0.5 7.7 93.9 5.5 0.0 0.4 149.3 11.2 15.6 34.5 0.3 0.0 37.8 5.2 0.0 0.6 7.9 17.8 21.8 1.2 0.0 16.4 128.6 METRN "C16orf23, MGC2601" ENSG00000103260 "Meteorin, glial cell differentiation regulator" Q9UJH8 16 715118-719655 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 299.3;choroid plexus: 238.6" "Cell type enriched" "Detected in many" 5 "Muller glia cells: 1153.9" "Cancer enhanced" "Detected in all" "glioma: 69.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MCF7: 178.2;PC-3: 133.1;SK-MEL-30: 93.5" "Region enhanced" "Detected in all" "cerebellum: 612.9" HPA051164 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted in brain" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 5: Muller glia cells - Visual perception" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA051164: AB_2681369" "unprognostic (1.60e-2)" "unprognostic (3.49e-1)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (7.49e-2)" "unprognostic (1.82e-1)" "unprognostic (2.59e-1)" "unprognostic (8.13e-2)" "unprognostic (2.35e-1)" "unprognostic (2.12e-2)" "unprognostic (3.32e-1)" "unprognostic (5.03e-3)" "unprognostic (3.62e-2)" "unprognostic (1.26e-1)" "unprognostic (3.09e-1)" "unprognostic (2.17e-2)" 16.1 36.3 238.0 4.0 233.8 1.5 14.1 203.7 299.3 15.5 238.6 30.7 4.1 17.3 3.0 10.4 37.0 2.5 56.8 209.7 210.3 29.2 49.9 16.8 2.1 258.1 239.0 5.2 46.1 5.5 88.0 3.7 208.5 25.4 1.2 3.0 25.2 13.1 23.3 11.9 12.0 2.9 244.4 12.3 22.2 15.3 258.3 2.4 30.6 5.1 1.8 20.5 11.3 237.4 8.9 73.4 14.2 72.4 24.6 13.8 22.9 17.5 8.7 6.9 4.4 11.0 21.5 1.5 39.6 12.4 26.3 32.6 2.1 17.0 1.1 4.7 32.0 2.9 13.3 57.1 15.1 6.5 9.2 33.3 18.3 2.1 4.2 21.3 2.3 20.3 5.3 1.7 5.2 178.2 2.4 22.0 5.2 9.8 133.1 24.3 16.4 24.4 18.4 2.6 22.5 28.5 6.9 18.9 93.5 1.6 28.6 12.6 8.0 19.4 36.8 22.7 15.4 11.0 3.3 1.7 30.3 4.8 46.6 0.0 0.1 0.2 0.8 0.3 0.5 1.2 0.4 0.8 0.0 0.1 0.2 0.5 0.0 0.5 0.3 0.2 1.0 0.1 238.0 233.8 203.7 299.3 209.7 210.3 258.1 239.0 208.5 244.4 258.3 237.4 46.7 0.0 2.2 91.4 8.5 3.8 17.1 3.3 0.0 45.5 79.5 75.8 16.3 48.6 1.8 16.5 14.6 0.6 26.7 29.0 50.9 8.4 8.0 230.7 54.8 21.5 27.4 2.7 6.6 5.1 2.1 15.1 5.6 14.4 0.0 2.7 20.0 39.5 6.4 70.7 5.7 10.7 2.0 7.8 6.5 25.8 11.1 6.6 10.6 8.4 1.1 1153.9 23.7 44.2 57.6 5.3 26.7 9.4 7.9 27.7 6.2 55.6 9.5 37.9 26.3 11.8 26.7 4.6 11.7 1.4 3.0 0.4 12.7 5.2 9.2 16.2 METRNL ENSG00000176845 "Meteorin like, glial cell differentiation regulator" Q641Q3 17 83079609-83095122 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 252.9" "Cell type enhanced" "Detected in many" "dendritic cells: 640.2;Macrophages: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 119.5;U-2197: 162.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023792 Uncertain "Secreted to blood" NA NA 445000 1300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA023792: AB_2144182" "unprognostic (7.99e-2)" "unprognostic (2.32e-1)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (6.41e-3)" "unprognostic (7.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (1.01e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-3)" "unprognostic (4.43e-1)" "unprognostic (2.23e-1)" "unprognostic (2.46e-1)" "unprognostic (1.61e-2)" 105.4 24.0 7.8 13.2 6.9 21.9 66.8 6.7 8.9 89.0 33.4 57.0 26.6 33.8 2.1 184.1 39.3 12.2 95.8 7.2 6.8 71.4 19.1 80.3 5.1 9.6 9.7 23.0 24.4 25.1 36.5 14.5 7.8 26.4 4.1 3.4 52.9 3.7 15.3 252.9 50.0 4.3 7.3 41.0 41.1 32.4 15.1 3.2 61.3 1.5 4.7 47.4 103.4 6.7 11.4 0.3 5.4 7.3 5.9 21.8 26.7 11.7 5.1 8.4 9.6 1.4 7.8 0.7 4.6 9.1 6.4 29.8 1.9 0.7 5.6 8.6 4.4 26.8 32.0 3.3 14.1 7.8 49.5 10.5 2.2 36.1 2.4 5.3 4.2 0.0 17.1 0.0 7.2 19.0 0.7 23.9 1.1 16.6 16.6 8.2 11.4 3.9 1.3 4.3 0.5 3.6 16.0 29.5 14.2 5.3 27.3 8.2 10.9 119.5 12.5 162.6 3.6 0.0 0.0 0.4 28.1 3.1 7.5 6.8 3.2 10.5 1.8 6.0 0.1 1.4 0.3 1.3 4.5 0.1 0.0 0.5 5.5 3.2 8.1 1.7 1.8 1.5 7.8 6.9 6.7 8.9 7.2 6.8 9.6 9.7 7.8 7.3 15.1 6.7 39.0 25.6 31.1 6.5 28.0 22.9 19.9 4.7 1.2 3.3 19.7 16.5 40.5 14.3 12.3 49.7 6.2 12.4 640.2 110.2 3.9 11.5 9.5 72.6 27.1 16.8 6.0 3.2 0.7 13.9 5.1 56.1 18.3 103.4 32.9 41.5 25.0 1.0 53.8 1.7 2.1 41.4 6.1 62.2 133.6 1.5 7.8 162.0 16.0 1.9 13.7 90.6 25.7 4.0 0.3 19.7 64.9 3.4 95.8 18.4 53.4 8.3 7.4 22.2 0.0 75.4 35.5 5.9 3.4 13.5 49.2 19.2 98.8 0.5 35.1 62.2 METTL24 "C6orf186, dJ71D21.2" ENSG00000053328 "Methyltransferase like 24" Q5JXM2 6 110245928-110358272 "Predicted secreted proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "smooth muscle: 14.2" "Group enriched" "Detected in some" 4 "Astrocytes: 30.0;Excitatory neurons: 23.8;Inhibitory neurons: 28.7;Late spermatids: 8.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 29 "T-cells: 3.5" "Cell line enhanced" "Detected in some" "HHSteC: 1.0;SCLC-21H: 1.6;SuSa: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037441, HPA037442" Uncertain "Secreted - unknown location" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA037441: AB_10670933, HPA037442: AB_10696931" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (9.31e-3)" "unprognostic (5.02e-2)" "unprognostic (5.21e-3)" "unprognostic (1.46e-1)" "unprognostic (6.12e-2)" "unprognostic (2.06e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.45e-2)" "unprognostic (5.96e-2)" "unprognostic (1.54e-4)" "unprognostic (4.08e-2)" "unprognostic (1.23e-2)" "unprognostic (1.63e-2)" "unprognostic (4.78e-3)" 1.8 1.6 1.4 1.6 2.3 0.0 1.7 2.1 1.9 3.9 8.1 5.9 1.4 7.5 2.2 4.0 6.0 5.8 3.0 1.7 1.8 3.9 0.9 1.6 0.1 1.6 2.2 5.6 1.3 2.5 2.1 0.4 1.4 4.9 4.2 1.4 0.4 7.1 0.0 0.5 2.1 14.2 2.0 0.7 2.4 2.1 1.8 1.0 1.3 1.1 0.6 4.7 1.6 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.3 2.1 1.9 1.7 1.8 1.6 2.2 1.4 2.0 1.8 1.2 0.0 0.0 0.0 30.0 0.3 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.4 1.5 0.1 0.0 0.0 23.8 0.0 0.0 0.8 0.0 0.4 0.0 0.5 0.0 0.0 0.0 1.7 28.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 3.7 0.0 0.6 0.0 31.7 5.4 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.3 2.1 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 197.8;Fibroblasts: 75.8;Granulosa cells: 93.3;Leydig cells: 53.7;Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 249.4;ASC TERT1: 249.6;HUVEC TERT2: 263.1;SH-SY5Y: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" 36.6 4.2 0.4 13.3 0.6 0.1 22.7 0.5 1.1 81.8 1.6 15.0 5.0 61.4 22.1 6.1 19.0 73.2 13.8 0.5 0.6 9.4 1.6 20.1 4.2 0.7 0.9 35.8 18.8 4.5 13.2 42.4 0.7 22.1 4.8 4.9 16.5 12.1 2.6 27.6 12.1 30.6 0.5 2.7 8.3 11.2 0.7 1.6 9.5 3.0 2.3 22.5 36.7 0.6 0.0 0.2 93.2 0.3 249.4 249.6 6.2 26.3 102.5 39.7 73.7 24.1 1.1 0.0 82.6 89.7 0.1 0.1 7.2 7.7 15.9 0.1 78.0 0.0 37.1 2.1 23.4 0.1 0.1 104.4 18.8 109.4 42.7 113.1 263.1 0.0 0.2 16.2 19.2 12.5 0.1 0.1 108.8 0.5 0.8 1.5 0.0 4.0 0.9 0.3 5.0 212.1 9.0 36.6 9.6 71.1 11.9 13.0 75.6 65.6 128.4 51.7 2.8 0.1 0.3 0.2 53.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.5 1.1 0.5 0.6 0.7 0.9 0.7 0.5 0.7 0.6 5.5 0.0 1.7 0.0 0.1 6.6 7.8 28.7 8.0 0.2 2.1 3.9 0.9 2.8 10.7 3.7 0.0 4.5 0.0 0.1 0.0 1.3 12.9 5.6 28.7 7.1 10.1 0.0 0.0 0.8 197.8 75.8 2.0 8.3 0.0 93.3 1.4 0.0 7.4 0.0 0.0 0.4 12.2 0.0 7.7 7.6 53.7 0.6 17.8 2.8 0.0 27.7 0.0 0.0 0.0 1.9 0.0 63.9 0.5 1.5 0.0 0.0 1.9 0.8 0.0 3.3 14.7 3.2 8.7 0.6 6.3 29.0 0.9 0.5 0.2 1.2 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 242.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.5;Extravillous trophoblasts: 1015.1;Fibroblasts: 579.7;Syncytiotrophoblasts: 252.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 31.7" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 172.2;BJ: 63.7;EFO-21: 150.4;HeLa: 55.9;SuSa: 137.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 42.6" HPA010553 Enhanced "Secreted to extracellular matrix" NA NA 3200000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" 141.7 10.9 3.5 5.4 5.0 3.5 79.7 31.7 9.2 59.9 1.8 37.8 7.2 242.1 11.1 35.0 25.8 28.2 54.4 4.8 0.8 3.1 12.7 8.7 4.8 2.9 0.4 2.4 5.5 2.4 3.7 94.5 1.9 6.4 42.0 7.9 17.2 49.7 28.5 38.7 19.0 142.1 0.0 1.9 23.6 6.9 1.7 3.2 14.4 118.1 3.4 43.1 60.7 6.6 1.4 5.7 1.6 2.6 29.4 12.4 172.2 63.7 1.2 0.8 1.1 2.3 1.0 0.6 150.4 19.8 1.6 9.1 0.6 13.1 0.0 0.5 0.4 1.6 55.9 1.9 0.4 1.3 0.6 8.7 4.4 7.3 0.0 3.3 0.0 2.0 2.7 3.7 52.7 0.8 1.9 0.8 3.2 0.9 2.9 1.2 1.3 6.5 6.5 2.6 0.7 0.9 1.9 0.7 1.0 137.1 24.0 0.8 2.3 10.7 21.5 45.7 3.0 2.1 1.9 2.3 6.0 0.7 0.1 2.9 0.8 0.7 0.2 0.7 0.4 0.1 0.1 0.1 0.4 0.3 0.4 0.1 1.1 0.2 0.5 0.3 0.0 0.3 3.5 5.0 31.7 9.2 4.8 0.8 2.9 0.4 1.9 0.0 1.7 6.6 61.5 12.8 5.8 0.3 0.5 23.1 0.4 1.8 0.6 0.2 0.6 0.9 7.0 0.0 2.0 0.0 0.0 140.5 0.5 0.0 0.0 0.5 0.3 5.1 3.9 20.1 0.0 0.0 0.2 0.0 1015.1 579.7 3.6 28.0 0.0 0.2 4.2 0.0 27.7 0.0 0.1 0.0 0.0 9.5 36.3 0.5 61.2 8.8 12.4 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.6 0.1 0.0 0.2 1.6 0.9 0.0 40.2 35.2 0.1 0.2 0.6 18.0 252.3 5.3 0.1 0.0 0.3 MFGE8 "BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10" ENSG00000140545 "Milk fat globule EGF and factor V/VIII domain containing" Q08431 15 88898683-88913381 "Cancer-related genes, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 407.0;Cone photoreceptor cells: 385.7;Rod photoreceptor cells: 978.7;Sertoli cells: 1084.7;Smooth muscle cells: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.9" "Group enriched" "Detected in many" 8 "granulocytes: 5.3;NK-cells: 7.7;T-cells: 14.9" "Cell line enhanced" "Detected in many" "ASC diff: 1784.6;ASC TERT1: 918.2;fHDF/TERT166: 660.4;HSkMC: 935.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002753, HPA002807" Enhanced Approved Cytosol "Secreted to blood" NA NA 2830000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "CAB002753: , HPA002807: AB_1078072" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (7.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.11e-3)" "unprognostic (6.27e-2)" "unprognostic (8.49e-2)" "unprognostic (3.99e-1)" "prognostic unfavorable (6.06e-9)" "prognostic unfavorable (3.08e-4)" "unprognostic (4.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.41e-3)" 237.2 95.2 44.2 45.2 49.6 3.7 226.7 56.4 61.8 272.8 52.4 113.7 21.2 444.7 77.0 67.6 361.8 120.2 485.8 41.6 47.2 69.0 15.6 137.2 47.4 55.9 47.4 228.5 36.5 18.9 49.3 79.6 55.6 129.3 29.3 68.7 97.1 195.8 264.3 118.9 106.9 162.7 47.0 40.7 124.9 38.3 46.5 18.8 90.6 124.1 36.9 163.6 223.4 55.6 19.7 85.4 78.7 98.7 1784.6 918.2 6.9 482.7 142.4 95.4 110.3 90.5 23.5 0.0 147.5 660.4 144.6 10.2 27.6 95.8 31.1 82.3 64.7 138.1 4.6 10.2 469.8 0.2 50.1 935.7 251.8 73.5 122.5 205.3 37.0 35.3 23.4 41.1 185.1 6.2 22.6 3.2 405.4 8.3 38.4 22.7 74.4 26.4 32.6 7.3 8.2 42.9 28.0 2.5 226.1 165.6 2.4 11.1 42.0 233.2 127.8 62.3 36.3 145.3 30.5 15.9 31.6 12.2 91.5 5.3 0.2 0.4 1.3 0.0 4.2 1.2 4.2 2.9 0.0 0.9 4.3 3.3 0.0 7.7 0.1 0.1 14.9 2.1 44.2 49.6 56.4 61.8 41.6 47.2 55.9 47.4 55.6 47.0 46.5 55.6 72.1 12.8 5.4 39.2 4.0 48.7 32.2 116.3 24.5 22.1 407.0 190.4 92.8 8.6 25.5 3.7 385.7 4.5 13.1 1.6 0.0 15.7 11.0 33.3 202.2 66.9 44.8 3.8 5.1 4.3 18.6 220.0 12.8 29.7 5.1 30.1 22.1 15.5 8.1 16.8 0.4 6.4 36.7 32.9 39.7 27.9 187.0 12.9 119.2 15.0 1.8 75.9 9.2 5.5 9.6 28.3 0.2 109.1 8.8 15.8 0.1 0.2 8.3 978.7 1084.7 51.8 476.0 3.3 9.0 21.7 35.9 5.3 12.5 25.8 2.0 10.2 MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A" Q9UM21 2 98619106-98731132 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.0" "Cell type enhanced" "Detected in many" "Microglial cells: 175.2;Proximal enterocytes: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 127.2;HUVEC TERT2: 48.3;JURKAT: 86.5;TIME: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA007608: AB_10602008" "prognostic unfavorable (4.30e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.48e-8)" "unprognostic (1.35e-1)" "unprognostic (2.28e-2)" "unprognostic (3.82e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-1)" "unprognostic (3.58e-1)" "unprognostic (2.80e-2)" "unprognostic (2.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" 11.2 7.8 13.2 20.8 17.8 96.0 12.5 26.1 15.6 8.9 15.1 24.4 29.5 5.8 3.7 6.3 7.0 12.7 7.6 13.1 15.2 27.5 9.7 16.9 21.1 16.4 15.8 3.2 38.8 28.0 9.8 19.6 15.5 7.5 25.5 5.4 25.9 6.4 3.8 4.1 43.8 11.5 18.1 8.1 11.3 6.3 15.5 20.5 8.7 4.7 18.2 13.1 4.7 22.9 8.8 1.7 3.4 7.3 0.0 0.0 127.2 0.0 0.1 0.9 0.0 21.0 10.6 0.0 18.9 0.0 2.4 0.4 7.2 1.0 0.2 10.6 7.9 0.5 0.0 36.7 0.2 17.8 6.4 0.0 4.7 0.0 0.7 0.3 48.3 86.5 1.6 9.2 0.0 17.3 39.3 30.9 1.1 7.6 1.4 9.8 0.0 10.5 24.8 17.6 10.4 3.3 2.5 32.2 4.8 9.2 7.6 23.8 78.8 0.0 4.0 0.1 2.6 3.2 7.6 2.2 0.0 26.7 0.6 7.0 5.1 12.7 20.8 1.0 27.5 3.6 25.2 23.7 3.8 2.5 32.6 27.2 14.0 15.3 2.5 17.1 16.0 12.5 13.2 17.8 26.1 15.6 13.1 15.2 16.4 15.8 15.5 18.1 15.5 22.9 80.8 54.5 25.7 19.2 22.7 9.9 21.1 6.1 11.4 19.8 28.2 15.6 13.4 11.5 17.6 22.0 4.2 6.2 116.9 92.4 21.5 20.8 12.7 14.2 3.8 39.8 53.0 6.3 58.0 29.8 77.9 7.2 19.4 35.1 13.3 5.1 18.9 10.4 57.2 48.8 48.6 41.3 34.6 33.9 18.3 17.5 2.5 54.5 10.6 175.2 21.0 13.4 89.6 36.7 42.0 21.6 58.2 2.2 31.4 17.8 132.4 27.3 7.1 4.8 6.6 6.8 4.9 2.5 7.7 8.6 10.5 14.9 112.2 0.7 40.9 30.2 MGP ENSG00000111341 "Matrix Gla protein" P08493 12 14880864-14885857 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 9375.3;Breast myoepithelial cells: 4639.0;Fibroblasts: 4233.6;Hepatic stellate cells: 1826.5;Leydig cells: 2016.2" "Cancer enriched" "Detected in all" 5 "breast cancer: 845.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.6" "Cell line enriched" "Detected in many" 5 "AN3-CA: 9874.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013949 Approved "Secreted to blood" NA NA 29000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "HPA013949: AB_1853599" "unprognostic (5.71e-3)" "unprognostic (5.85e-3)" "unprognostic (1.20e-3)" "unprognostic (2.83e-2)" "unprognostic (1.27e-1)" "unprognostic (1.21e-1)" "unprognostic (1.55e-2)" "unprognostic (4.17e-3)" "unprognostic (1.01e-2)" "unprognostic (6.93e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-2)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.55e-2)" "unprognostic (4.69e-2)" "unprognostic (7.50e-2)" "unprognostic (8.97e-3)" 1737.5 1510.2 50.6 187.4 63.8 1.6 3734.8 48.9 253.3 1738.8 198.1 1827.5 69.8 2043.8 752.9 218.2 2280.1 1083.5 2854.4 49.0 48.2 1316.9 58.1 1269.6 107.0 57.0 49.1 838.7 218.9 109.7 923.0 204.2 51.2 1955.5 277.3 7.5 2112.7 1140.7 177.0 357.6 819.0 1310.0 53.9 142.2 905.9 142.3 58.4 99.5 1500.7 275.0 65.9 987.7 1266.3 48.8 0.9 0.0 0.1 9874.6 1624.2 2.4 3.7 31.8 1.0 0.0 0.0 0.0 12.7 0.2 0.5 3.1 0.4 0.1 0.2 0.2 0.0 0.3 0.3 0.0 1.3 0.0 55.0 0.2 0.2 33.6 0.0 0.0 1.5 3.2 105.4 0.0 0.0 0.3 0.0 0.9 1.2 4.8 7.0 2.2 0.0 0.4 0.2 2.6 0.0 10.5 4.8 31.1 2.0 8.9 0.6 2.8 1810.9 0.1 21.7 11.1 1.2 3.6 28.7 0.5 0.1 1.1 9.0 0.6 8.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 50.6 63.8 48.9 253.3 49.0 48.2 57.0 49.1 51.2 53.9 58.4 48.8 451.0 19.2 72.8 1.3 29.9 149.3 220.4 0.3 19.9 0.5 9375.3 4639.0 70.2 8.6 187.5 115.8 4.2 19.0 85.7 0.1 1.9 2.3 16.9 14.7 355.8 856.1 0.0 18.7 0.2 83.4 13.5 4233.6 86.2 10.9 13.9 0.3 1826.5 6.0 30.8 0.0 0.1 0.0 0.0 9.4 219.9 67.9 2016.2 36.1 225.9 23.4 2.6 28.8 0.0 0.0 0.2 1.8 1.1 1301.8 17.0 164.3 0.0 0.7 25.8 6.8 841.5 558.8 847.0 8.2 6.1 25.8 118.5 39.5 54.5 140.6 0.0 74.6 MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 57.9;pituitary gland: 76.2;salivary gland: 43.3;stomach 1: 65.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 51.4;Breast myoepithelial cells: 171.7;Melanocytes: 103.2;monocytes: 30.0;Pancreatic endocrine cells: 66.8;Respiratory ciliated cells: 53.9" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Group enriched" "Detected in some" 29 "AN3-CA: 90.1;CAPAN-2: 80.6;SK-MEL-30: 271.9;WM-115: 247.7" HPA042369 Approved "Secreted to blood" NA NA 8270000 64000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 4: Stomach - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA042369: AB_10794420" "prognostic favorable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" 2.6 2.9 4.9 6.9 5.9 2.9 57.9 5.7 7.5 8.3 5.4 16.9 2.0 1.2 2.0 6.6 3.7 2.9 5.3 4.4 4.8 2.4 2.7 1.9 2.0 5.3 5.0 7.0 1.4 0.0 76.2 2.1 5.6 6.4 4.2 0.4 43.3 3.3 0.7 9.6 5.9 7.6 4.8 7.0 65.8 1.7 5.5 2.4 2.9 1.7 1.6 4.0 5.2 7.9 0.3 0.9 1.5 90.1 1.3 1.2 1.0 0.0 0.0 0.0 0.5 0.5 80.6 0.2 0.0 0.0 0.3 0.2 0.4 4.9 0.1 2.9 0.9 0.0 1.0 0.1 0.4 0.2 0.4 0.7 4.2 0.0 1.5 1.4 0.0 1.4 0.0 0.9 0.0 0.0 0.1 0.0 0.2 5.9 0.3 0.1 0.2 0.0 2.5 0.0 0.2 0.1 0.1 0.0 271.9 3.4 0.5 1.2 0.0 0.2 3.4 0.1 1.0 0.0 0.2 0.9 0.1 0.4 247.7 0.6 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 4.9 5.9 5.7 7.5 4.4 4.8 5.3 5.0 5.6 4.8 5.5 7.9 1.0 0.0 0.5 0.0 0.3 5.2 0.1 11.2 0.6 0.0 51.4 171.7 0.6 0.0 4.9 0.0 0.0 0.8 0.5 1.7 0.0 0.5 0.0 0.9 0.0 1.4 0.0 0.0 0.0 3.2 0.1 1.1 14.3 0.2 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.1 4.1 0.0 0.7 0.3 0.6 0.2 103.2 0.0 30.0 0.0 0.0 0.0 0.0 66.8 5.1 0.0 0.1 0.8 0.4 0.0 53.9 0.0 0.0 0.2 1.3 0.1 0.6 6.1 1.3 0.7 0.3 0.8 4.1 0.5 MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894383-23895227 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 2032.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 4974.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003868, CAB005284" Approved Enhanced Nucleoplasm,Cytosol "Secreted to blood" No No 13800000 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "CAB005284: AB_648587, HPA003868: AB_1079290" "unprognostic (1.68e-1)" "unprognostic (7.79e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (9.48e-2)" "unprognostic (1.22e-3)" "unprognostic (2.17e-2)" "unprognostic (1.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" 233.3 467.9 195.8 119.5 200.0 146.0 223.3 209.3 450.0 235.0 204.3 194.3 98.9 205.3 49.8 514.2 219.4 20.9 290.8 245.2 289.7 530.3 484.6 208.2 61.5 225.2 224.7 223.7 255.7 127.8 368.0 100.4 217.2 318.7 35.2 23.8 233.6 132.8 99.3 302.5 171.7 43.4 250.8 204.5 230.7 113.5 204.2 65.0 274.0 19.5 46.2 255.8 316.7 369.4 1698.3 605.3 122.2 499.0 58.9 111.3 590.7 581.2 154.7 298.9 382.1 526.4 364.4 761.3 499.8 83.1 115.2 788.1 155.0 546.8 51.5 642.2 4974.4 286.2 534.6 1126.5 225.3 1077.2 758.6 230.9 354.9 173.8 103.5 248.8 241.3 589.4 466.9 540.1 122.2 1476.0 827.0 2345.5 532.8 488.6 2365.8 1040.4 127.9 2398.8 294.7 179.6 1080.9 1290.4 380.3 531.9 1374.7 37.6 671.2 442.6 424.7 232.5 1227.9 127.3 9.9 1647.2 732.5 1020.9 967.5 484.6 477.9 484.2 543.5 443.5 872.4 579.5 1250.8 1527.9 1221.7 983.3 796.9 1378.9 1040.4 928.4 166.8 1158.9 383.3 977.1 1258.3 1803.3 195.8 200.0 209.3 450.0 245.2 289.7 225.2 224.7 217.2 250.8 204.2 369.4 161.2 157.0 199.4 21.5 433.4 672.2 295.5 1134.8 1027.2 28.3 856.0 778.2 0.3 479.0 489.1 693.4 2.1 462.7 171.3 317.9 1649.4 859.0 190.5 733.7 485.3 248.5 348.9 455.7 17.1 377.7 885.0 336.2 606.5 844.3 180.3 192.2 261.6 885.2 278.8 21.9 24.1 432.5 697.8 207.7 505.2 153.9 336.1 232.6 773.7 19.7 217.0 59.5 155.5 17.6 52.8 649.9 360.4 302.8 1337.1 269.8 476.8 2032.7 404.6 33.2 138.1 338.1 349.7 21.3 124.2 1511.3 758.8 686.0 386.3 227.6 473.0 256.1 MLN ENSG00000096395 Motilin P12872 6 33794673-33804003 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 331 "intestine: 254.8" "Cell type enriched" "Detected in single" 11 "Enteroendocrine cells: 3.5" "Cancer enriched" "Detected in some" 6 "testis cancer: 5.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.0;SuSa: 1.1;TIME: 1.3" "Low region specificity" "Detected in many" "HPA069392, HPA077622" Enhanced "Secreted to blood" NA NA 450000 200000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA069392: AB_2686136, HPA077622: " "unprognostic (7.70e-2)" "unprognostic (6.70e-2)" "unprognostic (4.44e-2)" "unprognostic (3.14e-1)" 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.5 254.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.1 0.3 43.3 0.0 0.2 0.0 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.5 0.7 0.4 0.7 0.2 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 75.7;stomach 1: 47.6;urinary bladder: 52.2" "Cell type enriched" "Detected in many" 10 "Pancreatic endocrine cells: 2239.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1139.1;HBF TERT88: 1094.4;HUVEC TERT2: 2954.4;WM-115: 1454.1" "Not detected" "Not detected" HPA004920 Approved Vesicles "Secreted to extracellular matrix" NA NA 7730000 55000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" 0.3 0.1 0.0 26.7 0.0 0.3 0.2 0.0 1.3 0.1 0.0 6.1 7.9 10.7 0.0 4.2 0.1 75.7 0.4 0.0 0.1 1.0 0.8 6.7 0.1 0.0 0.0 0.0 1.8 0.0 0.1 7.2 0.0 0.4 6.8 0.0 6.9 0.2 0.0 0.6 13.0 1.2 0.0 2.1 47.6 0.1 0.1 0.3 0.2 0.0 1.7 52.2 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.1 0.0 517.1 1139.1 456.6 118.2 9.1 1.0 0.0 5.2 275.5 175.2 4.6 0.0 160.0 1094.4 0.0 1.0 0.0 0.0 0.0 2.9 0.0 0.5 0.3 0.8 470.1 39.6 0.1 2954.4 0.0 1.5 0.5 0.3 0.0 0.0 0.0 0.4 189.3 20.8 0.0 0.1 0.0 0.7 2.2 0.0 0.1 4.8 0.0 1.6 0.1 0.5 0.0 155.0 374.1 0.6 16.8 1.3 0.1 0.0 0.0 8.8 0.0 1454.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.3 3.2 2.6 0.0 0.2 2.3 22.4 90.4 0.0 0.0 0.0 0.0 0.1 30.0 15.8 3.7 0.0 0.0 0.0 0.2 0.0 143.7 0.0 0.1 0.2 113.2 0.0 0.0 0.1 204.8 0.1 11.5 25.5 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 1.9 0.4 0.0 0.0 15.5 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2239.5 1.2 0.0 0.0 30.9 0.7 0.2 1.3 0.0 0.0 1.8 10.5 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 44.3 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "endometrium 1: 265.4" "Cell type enriched" "Detected in some" 38 "Basal respiratory cells: 3913.2" "Group enriched" "Detected in many" 4 "cervical cancer: 47.8;head and neck cancer: 102.2;lung cancer: 42.3" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 11.8;HUVEC TERT2: 15.1;SCLC-21H: 4.7" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 765000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favorable (7.12e-4)" 0.1 0.0 0.1 7.7 0.0 0.1 0.1 0.0 0.8 1.2 0.0 0.4 1.1 265.4 0.0 0.2 0.0 1.3 0.0 0.2 0.3 0.1 1.0 2.0 0.1 0.1 0.3 0.2 0.2 0.0 0.0 1.3 0.3 1.4 0.2 0.0 1.6 0.0 0.0 0.1 0.8 0.2 0.0 0.0 2.9 0.5 1.9 0.6 0.0 0.2 0.7 4.4 3.2 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 11.8 0.6 0.1 0.1 0.3 0.0 0.0 3.3 1.8 0.2 2.7 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.5 0.0 15.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 2.8 0.5 1.6 0.0 0.0 0.0 0.0 0.6 4.7 0.0 2.4 0.0 0.0 0.8 0.0 0.0 1.9 3.5 1.2 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.3 0.1 0.3 0.3 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 51.3 3913.2 0.0 0.0 0.7 0.0 0.1 0.0 85.4 29.5 0.0 0.0 0.0 0.4 0.0 34.0 6.1 6.4 2.5 9.0 0.0 0.0 0.0 14.6 0.0 6.3 0.0 12.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 9.5 1.3 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 102.5 0.1 0.0 0.0 42.5 0.0 0.1 29.3 0.0 0.0 0.0 11.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.2 MMP11 STMY3 ENSG00000099953 "Matrix metallopeptidase 11" P24347 22 23768226-23784316 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 64.8;endometrium 1: 142.8;placenta: 39.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 84.9;Extravillous trophoblasts: 37.6;Granulosa cells: 61.9;Smooth muscle cells: 35.8" "Cancer enhanced" "Detected in all" "pancreatic cancer: 119.1" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 4.4" "Cell line enhanced" "Detected in many" "AN3-CA: 38.4;hTERT-RPE1: 19.7;REH: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002593, HPA055204, HPA068864" Approved Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 640000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Cytosol "CAB002593: , HPA055204: , HPA068864: AB_2686051" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.84e-3)" "unprognostic (2.77e-2)" "unprognostic (6.73e-2)" "unprognostic (2.14e-2)" "unprognostic (5.15e-1)" "unprognostic (2.73e-2)" "unprognostic (2.20e-1)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.05e-2)" "unprognostic (6.78e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-2)" 3.3 1.6 0.4 1.4 0.3 0.5 2.2 0.3 1.2 64.8 0.3 3.9 6.8 142.8 0.1 1.0 5.7 6.8 7.2 0.3 0.4 2.5 0.6 1.4 3.9 0.4 0.4 12.5 1.3 3.3 0.5 39.6 0.4 1.9 3.5 0.0 5.3 1.5 0.9 3.8 6.0 9.4 0.4 1.4 2.6 6.7 0.4 3.1 1.3 0.9 1.7 2.9 3.6 0.4 0.3 0.0 4.8 38.4 5.7 8.3 0.1 0.6 10.4 1.3 0.8 0.4 1.3 1.3 5.1 2.8 1.8 0.2 2.2 0.0 0.4 0.0 0.8 0.0 0.0 2.2 4.2 0.0 0.0 5.4 0.9 1.1 0.1 19.7 6.0 0.4 0.6 0.0 1.4 0.3 0.1 0.1 1.4 1.2 0.2 16.6 0.0 0.4 0.7 0.0 6.0 10.3 3.9 0.6 0.0 5.9 3.6 0.0 2.7 0.6 0.0 1.6 0.1 0.1 0.2 5.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.4 0.3 0.3 1.2 0.3 0.4 0.4 0.4 0.4 0.4 0.4 0.4 1.2 0.0 2.5 0.3 3.4 1.0 0.8 0.8 0.6 0.4 1.9 0.5 6.1 1.5 0.1 0.0 0.0 0.7 1.8 0.4 1.9 8.6 10.3 4.4 84.9 0.9 1.8 0.0 0.2 0.7 37.6 8.4 1.5 4.1 1.3 61.9 1.1 0.0 0.8 0.0 0.4 1.3 2.0 0.0 1.1 10.5 0.6 1.0 1.8 1.0 0.0 0.3 0.0 0.0 0.2 1.4 0.2 0.4 0.2 0.5 0.1 2.2 0.8 0.5 0.0 2.7 35.8 3.1 5.5 0.5 0.6 18.6 2.0 5.7 1.0 0.3 MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102874982 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.7;lymphoid tissue: 40.4;urinary bladder: 16.0" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 303.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BJ: 3.3;fHDF/TERT166: 11.4;hTEC/SVTERT24-B: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" 0.5 0.0 0.0 40.4 0.1 0.0 0.4 0.0 0.0 0.1 0.0 13.5 6.8 0.6 0.0 0.4 0.0 2.6 0.0 0.0 0.3 0.9 0.1 0.6 7.0 0.1 0.1 0.0 0.1 0.0 0.0 7.4 0.1 1.3 15.7 0.0 2.4 0.0 0.0 0.5 7.8 2.2 0.1 3.7 3.5 0.0 0.1 3.9 0.0 0.0 19.4 16.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 11.4 0.1 0.4 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 18.6 303.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.0 2.2 MMP13 CLG3 ENSG00000137745 "Matrix metallopeptidase 13" P45452 11 102942995-102955732 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "urinary bladder: 12.9" "Cell type enriched" "Detected in some" 12 "Basal respiratory cells: 426.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 70.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 17.9;PC-3: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB002742 Supported "Secreted to extracellular matrix" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB002742: " "unprognostic (8.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.75e-2)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" "unprognostic (1.59e-3)" "unprognostic (1.32e-1)" "unprognostic (6.35e-3)" "unprognostic (1.69e-1)" "unprognostic (7.55e-3)" "unprognostic (2.24e-1)" "unprognostic (1.73e-8)" "unprognostic (2.12e-2)" "unprognostic (3.14e-1)" "unprognostic (4.14e-2)" "unprognostic (4.33e-2)" 0.1 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 12.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 17.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.0 6.7 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 2.4 1.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 426.0 0.0 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.8 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP17 MT4-MMP ENSG00000198598 "Matrix metallopeptidase 17" Q9ULZ9 12 131828393-131851783 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.2" "Group enriched" "Detected in many" 5 "Excitatory neurons: 47.0;Inhibitory neurons: 14.3;Melanocytes: 28.4;Oligodendrocyte precursor cells: 26.7" "Cancer enriched" "Detected in many" 10 "melanoma: 29.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "REH: 29.6;SK-MEL-30: 60.4;WM-115: 87.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (9.11e-2)" "unprognostic (1.27e-2)" "unprognostic (1.69e-2)" "unprognostic (3.71e-3)" "unprognostic (5.62e-2)" "unprognostic (1.85e-2)" "unprognostic (8.90e-3)" "unprognostic (2.14e-2)" "unprognostic (2.60e-1)" "unprognostic (2.66e-4)" "unprognostic (7.68e-2)" "unprognostic (5.88e-2)" "unprognostic (9.26e-10)" "unprognostic (1.15e-2)" "unprognostic (2.65e-1)" "unprognostic (1.21e-3)" "unprognostic (2.81e-2)" 3.9 0.8 9.9 1.2 16.6 0.9 4.0 0.0 37.2 10.8 0.0 6.4 0.3 3.7 0.0 1.7 2.4 1.0 2.2 31.7 9.2 1.0 1.0 2.0 0.9 0.0 0.2 11.6 2.0 0.1 1.5 0.1 0.3 2.9 0.1 0.1 3.1 0.5 0.9 4.7 2.7 0.3 0.0 1.7 1.6 3.2 6.3 0.0 1.7 0.0 0.2 2.7 4.7 8.8 0.3 11.5 0.0 0.5 2.3 2.9 0.1 7.2 7.9 2.1 3.3 0.0 1.4 0.0 5.2 1.8 1.4 3.8 1.3 1.5 0.0 0.0 0.7 1.1 3.8 0.0 3.6 0.0 7.2 2.7 1.2 2.4 0.0 0.5 4.0 0.0 2.0 0.0 1.0 8.3 0.0 11.5 4.6 1.6 7.3 29.6 0.0 3.9 0.0 0.0 3.7 2.0 1.0 0.2 60.4 0.5 7.4 12.8 5.8 0.7 0.9 6.3 0.6 0.0 0.0 0.0 2.4 0.3 87.5 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 9.9 16.6 0.0 37.2 31.7 9.2 0.0 0.2 0.3 0.0 6.3 8.8 0.6 0.0 0.0 2.9 2.3 2.5 0.1 1.7 0.6 1.0 2.3 1.8 1.2 1.5 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.5 0.0 0.0 47.0 0.2 0.2 5.4 0.0 0.4 0.0 0.7 1.1 0.0 0.6 3.3 14.3 0.0 2.0 2.6 1.0 0.4 0.9 3.4 28.4 3.7 2.4 0.1 0.0 26.7 2.9 0.0 0.0 1.9 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.8 1.4 0.4 0.4 0.1 1.1 0.0 0.2 5.3 0.0 0.2 MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.4;Fibroblasts: 52.8;Hofbauer cells: 30.8;Kupffer cells: 35.7;Langerhans cells: 100.7;Macrophages: 61.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 75.6" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "HPA070804: AB_2686315" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" 58.5 3.6 0.0 11.4 0.1 0.7 18.3 0.0 0.3 10.4 0.5 7.3 1.2 20.7 0.5 2.3 17.2 25.6 8.8 0.1 0.1 5.7 2.7 25.4 2.8 0.1 0.1 11.9 7.2 0.5 0.8 10.8 0.2 3.3 3.3 0.1 3.1 2.3 0.9 5.5 8.7 8.7 0.1 27.4 9.6 0.4 1.3 2.9 4.4 0.6 6.9 9.6 6.2 0.1 1.5 0.0 0.2 0.0 7.8 12.4 75.6 10.1 10.6 3.9 4.4 0.6 0.6 0.0 0.0 12.8 0.3 0.0 0.0 3.0 4.0 0.8 0.0 0.0 0.3 0.1 6.5 0.0 0.6 12.1 0.4 1.9 2.4 6.2 0.7 0.0 0.2 0.1 11.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 2.8 0.0 1.7 4.7 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.2 15.7 2.2 5.0 0.2 0.3 0.1 0.0 0.0 8.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.2 0.1 1.3 0.1 2.8 0.0 4.6 0.7 1.3 7.1 0.3 1.9 0.6 0.4 0.3 0.3 0.7 11.5 3.3 0.0 4.2 18.6 0.7 0.0 0.0 0.3 0.5 2.4 20.8 1.5 0.0 0.0 0.2 0.5 54.4 52.8 1.1 1.7 2.5 0.4 3.6 0.7 30.8 0.0 0.2 0.1 0.0 35.7 100.7 0.9 5.9 61.2 12.4 1.9 22.5 0.4 0.0 0.0 0.3 0.1 0.0 5.3 1.0 0.3 0.0 0.1 1.5 1.7 0.0 3.8 7.6 0.2 0.2 1.0 4.3 18.7 0.9 0.2 0.0 0.4 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP20 ENSG00000137674 "Matrix metallopeptidase 20" O60882 11 102576832-102625332 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 7 "Early spermatids: 91.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "OE19: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (4.62e-3)" "unprognostic (2.61e-2)" "unprognostic (1.68e-3)" "unprognostic (1.75e-1)" "unprognostic (2.13e-1)" "unprognostic (3.06e-1)" "unprognostic (2.97e-2)" "unprognostic (6.75e-2)" "unprognostic (9.58e-5)" "unprognostic (6.10e-2)" "unprognostic (2.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 12.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.4 MMP21 ENSG00000154485 "Matrix metallopeptidase 21" Q8N119 10 125753580-125775821 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" Heterotaxy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "epididymis: 53.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Granulosa cells: 1.4;Microglial cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.32e-2)" "unprognostic (1.28e-1)" "unprognostic (8.51e-2)" "unprognostic (2.19e-2)" "unprognostic (4.02e-2)" "unprognostic (2.21e-2)" "unprognostic (4.22e-3)" "unprognostic (1.01e-1)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (2.89e-2)" "unprognostic (3.62e-2)" "unprognostic (9.70e-8)" "unprognostic (1.30e-2)" "unprognostic (7.69e-2)" "unprognostic (7.00e-2)" "unprognostic (2.18e-1)" 0.2 0.3 0.4 0.6 0.7 0.7 0.2 1.7 0.7 0.2 0.2 0.2 0.5 0.5 53.9 0.5 0.4 0.7 0.8 0.5 0.4 0.1 0.3 0.2 1.0 0.3 0.3 3.7 0.7 0.0 0.1 0.1 0.2 0.5 0.1 1.8 1.2 0.2 0.3 1.2 0.4 0.2 0.1 0.6 0.4 1.0 0.5 0.0 0.5 0.0 0.2 0.2 0.0 0.9 0.4 0.2 0.6 0.4 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.4 0.1 0.9 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.2 0.2 0.3 0.3 0.0 0.3 0.2 0.1 0.1 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.2 0.1 0.1 0.2 0.5 0.2 0.2 0.3 0.5 0.4 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.7 0.7 0.5 0.4 0.3 0.3 0.2 0.1 0.5 0.9 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 1.4 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.5 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Excitatory neurons: 24.6;Horizontal cells: 15.2;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.0;Proximal tubular cells: 11.4" "Cancer enhanced" "Detected in many" "renal cancer: 11.4;testis cancer: 10.8" "Region enriched" "Detected in all" 5 "cerebellum: 40.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.3;CACO-2: 56.0;EFO-21: 15.8;RPTEC TERT1: 24.6;U-2 OS: 17.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 51.5" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" Yes No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favorable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" 3.4 1.0 6.1 0.5 5.8 0.7 0.5 40.0 8.1 0.7 3.5 0.7 2.1 1.3 0.1 0.3 2.2 0.6 0.6 6.0 5.6 7.8 0.5 4.7 0.4 4.4 5.6 0.4 5.8 0.3 3.8 0.2 5.4 1.7 0.2 2.5 0.5 4.2 0.3 1.2 1.4 2.0 2.7 0.4 0.6 0.4 7.2 0.0 0.7 0.1 0.0 0.4 0.3 4.8 0.6 36.3 0.1 0.2 0.2 0.0 1.0 1.9 2.3 3.8 2.0 56.0 9.7 0.0 15.8 2.5 1.2 0.6 8.5 0.0 1.6 0.2 0.3 1.9 1.2 0.6 0.0 0.1 0.4 0.2 0.2 0.1 0.1 1.0 0.1 0.1 0.1 0.5 0.4 0.5 0.1 0.2 13.6 0.1 2.4 0.1 0.2 0.0 24.6 0.1 14.1 9.7 2.5 0.7 0.3 2.9 0.5 0.3 0.6 7.4 17.7 1.8 0.7 0.3 0.2 0.1 1.6 0.2 1.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 6.1 5.8 40.0 8.1 6.0 5.6 4.4 5.6 5.4 2.7 7.2 4.8 0.3 16.0 1.5 5.2 0.0 0.1 0.2 0.0 0.0 3.9 0.2 0.8 0.5 8.6 1.3 1.8 0.0 0.1 0.1 0.7 5.9 8.5 0.6 0.8 0.3 1.4 0.0 0.0 24.6 0.9 0.1 0.6 0.0 0.5 0.0 0.1 0.4 0.4 0.0 15.2 38.4 0.1 0.0 0.6 0.0 0.0 0.3 0.1 1.8 10.3 0.0 0.2 0.0 12.5 12.0 1.9 0.1 0.0 0.0 0.4 2.3 11.4 0.0 0.4 0.0 0.2 0.2 0.1 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.1 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 MMP26 "endometase, MGC126590, MGC126592" ENSG00000167346 "Matrix metallopeptidase 26" Q9NRE1 11 4704927-4992429 "Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "endometrium 1: 13.1" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 44.8;Glandular and luminal cells: 171.1" "Cancer enriched" "Detected in some" 4 "endometrial cancer: 8.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 44: Endometrium - Transcription" "unprognostic (4.21e-3)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 44.8 14.6 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 171.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;salivary gland: 286.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.4;Basal respiratory cells: 25.8;Early spermatids: 24.2;Extravillous trophoblasts: 13.4;Fibroblasts: 17.9;Prostatic glandular cells: 11.9;Smooth muscle cells: 10.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 4 "thalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BJ: 1545.7;BJ hTERT+: 4229.3;fHDF/TERT166: 1846.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 460000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 90.7 0.1 0.3 20.1 0.4 0.0 36.6 0.2 1.6 0.3 0.1 6.1 2.4 38.1 0.2 0.8 0.2 1.9 0.2 0.4 1.6 0.4 1.6 0.3 0.0 0.4 0.4 0.1 0.3 0.1 0.9 0.4 0.3 2.2 2.3 0.0 286.1 2.2 39.6 63.7 4.5 1.6 0.3 0.0 10.5 0.1 7.3 0.1 2.6 0.4 1.3 13.9 0.5 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1545.7 4229.3 27.0 8.7 0.1 0.2 0.0 0.0 1846.6 96.9 0.0 0.1 0.1 45.1 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 4.6 0.2 122.0 5.3 0.0 0.0 0.0 0.2 0.3 4.7 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.9 0.0 0.3 0.0 140.5 13.1 1.6 0.5 0.0 0.0 0.2 56.8 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.6 0.4 1.6 0.4 0.4 0.3 0.3 7.3 0.3 0.0 3.2 0.0 0.0 0.0 8.4 20.4 25.8 0.0 0.0 0.1 0.1 0.3 4.3 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.8 24.2 0.0 0.3 0.5 0.0 0.0 0.2 1.4 13.4 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.1 0.0 2.2 1.2 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 4.0 0.0 0.0 11.9 1.0 0.9 0.1 0.0 0.0 1.8 10.2 0.0 1.8 0.0 3.4 0.3 0.6 0.0 0.8 7.4 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 509.9;salivary gland: 267.9;urinary bladder: 211.2" "Cell type enriched" "Detected in many" 8 "Ductal cells: 8176.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 145.9;CAPAN-2: 815.9;EFO-21: 189.8;RPTEC TERT1: 350.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 35000 "Cluster 5: Breast - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 3.8 0.1 0.0 2.0 0.0 0.3 168.7 0.0 0.3 13.3 0.0 1.6 0.6 97.4 27.9 21.3 91.2 509.9 0.2 0.0 0.0 140.2 3.4 31.6 1.9 0.0 0.0 0.7 85.2 0.0 0.3 0.8 0.0 54.0 1.0 0.0 267.9 34.9 0.1 32.4 0.6 4.8 0.0 0.2 7.3 0.6 0.4 3.3 0.4 0.0 29.3 211.2 1.7 0.0 0.2 145.9 0.0 0.4 0.0 0.0 0.2 0.0 2.1 0.1 0.1 1.9 815.9 0.0 189.8 0.0 0.0 1.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.6 1.0 0.1 0.2 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.5 11.8 0.0 0.0 0.0 0.0 350.1 1.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.1 0.0 0.7 3.0 0.0 1.6 0.1 0.6 0.4 1.0 5.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 86.6 43.3 0.0 1.5 1.0 382.2 135.4 1.2 0.0 124.2 93.7 0.7 100.1 401.2 1017.0 0.0 0.7 2.9 1.2 0.0 8176.2 6.1 62.1 3.3 8.8 0.0 0.0 0.0 209.4 0.3 3.4 0.0 124.6 2.5 0.0 0.0 0.0 98.0 0.0 0.0 0.0 38.7 0.6 0.3 10.3 11.8 12.6 0.0 0.0 65.2 0.0 0.0 0.0 0.0 850.9 0.0 0.0 0.1 603.3 0.0 33.9 72.6 0.0 0.0 0.0 31.4 0.1 0.2 17.0 2.4 0.8 3.6 0.0 2.3 840.8 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 501.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 4.0;Macrophages: 1.5" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cell line enriched" "Detected in some" 8 "WM-115: 70.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 360000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 0.5 0.0 0.0 0.3 0.1 501.1 0.2 0.1 0.2 0.0 0.2 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.6 4.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.2 0.0 13.8 0.1 0.0 0.6 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 207.4" "Group enriched" "Detected in some" 4 "dendritic cells: 156.0;Kupffer cells: 409.8;Macrophages: 174.6;monocytes: 218.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 290.5;intermediate monocyte: 209.9;myeloid DC: 144.7;non-classical monocyte: 245.2;plasmacytoid DC: 204.9" "Group enriched" "Detected in many" 6 "dendritic cells: 204.9;monocytes: 290.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA046801 Approved "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" 29.2 15.8 1.5 112.4 1.6 21.3 13.5 1.7 2.4 11.6 3.2 32.9 40.9 10.9 3.7 12.6 6.9 36.2 10.3 1.4 2.1 6.0 41.1 35.4 96.3 3.3 1.9 4.9 4.6 4.6 1.6 35.8 2.5 8.0 43.4 0.3 7.3 9.3 3.9 7.1 52.8 28.2 2.9 207.4 19.2 4.5 4.0 42.8 5.9 8.3 75.2 42.7 2.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 290.5 8.4 0.5 209.9 0.5 12.6 0.3 0.2 144.7 14.0 0.2 0.1 38.5 1.2 245.2 204.9 0.6 214.5 1.5 1.6 1.7 2.4 1.4 2.1 3.3 1.9 2.5 2.9 4.0 4.0 0.7 0.0 7.9 0.0 33.8 1.1 0.0 0.0 1.2 0.0 0.3 0.9 1.7 1.5 0.6 0.0 0.0 0.3 156.0 0.1 0.0 0.0 0.2 0.0 0.1 1.7 0.0 4.4 0.0 0.0 0.6 0.8 0.5 0.1 2.5 0.0 4.6 3.7 52.4 0.0 0.0 0.0 0.0 409.8 48.0 0.6 0.0 174.6 1.8 10.3 218.2 0.2 7.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 6.6 0.7 0.4 0.0 0.0 0.3 1.6 0.3 2.7 0.0 0.0 0.1 MSMB "IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94" ENSG00000263639 "Microseminoprotein beta" P08118 10 46033307-46048180 "Cancer-related genes, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "prostate: 9384.0" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 10715.4" "Cancer enriched" "Detected in many" 42 "prostate cancer: 3435.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 25.6;NB-4: 21.6;RPMI-8226: 11.3;SH-SY5Y: 6.1;SK-BR-3: 5.9;U-2197: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB026357, HPA051257" Enhanced "Secreted in male reproductive system" NA NA 6000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB026357: , HPA051257: AB_2681410" "unprognostic (6.47e-2)" "unprognostic (7.21e-3)" "unprognostic (1.37e-2)" "unprognostic (8.18e-3)" "unprognostic (4.28e-3)" "unprognostic (9.24e-3)" "unprognostic (1.66e-1)" "unprognostic (8.66e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.19e-4)" 5.1 4.5 0.0 3.0 0.0 0.1 20.5 0.0 0.0 3.2 0.0 2.8 10.3 0.3 45.1 12.3 4.6 3.0 0.5 0.0 0.0 1.8 1.8 29.9 0.2 0.0 0.0 0.3 2.3 0.2 0.5 0.6 0.0 9384.0 0.1 0.0 31.9 0.6 0.4 39.7 2.3 0.0 0.0 0.7 552.3 10.1 0.0 1.0 0.7 0.0 10.0 7.2 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 25.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 21.6 0.2 0.0 0.0 0.0 0.0 11.3 0.0 1.6 1.0 6.1 0.0 5.9 0.0 0.2 0.4 0.0 0.0 0.0 0.0 12.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.3 0.0 195.9 586.4 0.0 0.0 6.4 1.3 0.0 4.3 2203.2 0.0 0.0 2.1 0.1 0.3 0.0 0.1 48.9 0.6 0.0 10.7 0.0 0.0 0.1 0.2 0.4 9.5 404.2 0.2 1.3 0.0 0.0 1.2 0.2 0.0 0.0 0.8 419.1 0.0 0.0 78.8 0.3 30.5 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.8 29.6 0.0 0.8 10715.4 0.3 0.0 570.6 0.0 0.0 0.0 271.0 0.5 1.4 0.0 0.4 1.5 14.3 0.0 0.1 192.4 MSMP "PC-3, PSMP" ENSG00000215183 "Microseminoprotein, prostate associated" Q1L6U9 9 35752990-35756613 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;choroid plexus: 1.1;pituitary gland: 1.5;placenta: 1.2" "Group enriched" "Detected in some" 50 "Early spermatids: 96.3;Late spermatids: 216.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 85.7;PC-3: 108.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA055174 Uncertain Supported Vesicles,Cytosol "Secreted in other tissues" No No 30000 "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Vesicles Cytosol "HPA055174: AB_2682726" 0.2 0.0 0.6 0.2 0.3 0.0 0.1 0.4 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.2 1.5 0.4 0.0 0.0 0.0 1.5 1.2 0.9 0.0 0.1 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 85.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.6 0.3 0.4 0.8 0.3 0.3 1.5 0.4 0.9 0.6 0.3 0.4 1.3 0.0 1.1 0.0 1.1 0.4 1.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 1.4 96.3 0.6 0.1 3.1 0.0 0.0 0.0 2.0 0.2 0.3 0.0 0.2 0.0 0.5 2.5 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.8 216.6 0.3 0.1 1.8 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.1 0.7 0.1 1.5 0.0 0.4 0.2 0.5 0.0 0.0 0.1 0.8 0.5 0.0 0.1 0.3 0.2 0.1 0.3 1.3 MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 10 "liver: 927.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 362.8" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 84.6;NB-4: 17.3;U-266/70: 21.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024036 Approved "Secreted to blood" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA024036: AB_1854147" "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 29.3 28.0 8.1 1.0 8.3 6.3 8.2 8.8 14.0 12.6 8.1 5.1 50.6 8.9 11.3 7.3 10.5 7.4 4.9 8.1 8.4 96.9 927.9 5.9 3.6 8.4 8.4 12.5 16.4 9.4 29.3 5.8 8.3 12.9 2.1 5.3 8.1 5.1 3.6 14.8 31.1 2.1 8.1 13.9 8.8 34.9 8.2 2.2 36.4 2.9 1.7 6.0 6.9 8.3 0.2 0.4 1.2 2.0 3.7 7.6 3.7 1.1 1.4 0.6 0.8 3.9 1.2 0.3 2.6 1.3 0.5 0.8 0.6 1.5 0.6 1.3 0.7 0.6 2.6 84.6 5.8 0.0 1.6 10.2 2.6 0.7 2.1 14.1 1.4 3.5 0.7 9.9 1.9 0.6 0.5 17.3 0.2 1.1 1.0 0.4 0.5 2.2 4.2 0.6 0.2 2.8 0.0 1.6 0.4 2.5 1.5 5.7 0.9 1.9 0.6 0.1 0.2 21.8 2.9 0.5 2.2 3.2 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 8.3 8.8 14.0 8.1 8.4 8.4 8.4 8.3 8.1 8.2 8.3 3.1 6.4 3.9 10.1 3.5 2.9 4.6 5.8 6.8 8.2 6.1 10.2 2.2 45.8 5.4 27.6 8.4 4.8 1.0 5.1 62.6 6.9 7.6 2.3 3.5 3.4 8.3 29.7 1.1 3.9 19.7 5.2 9.2 3.2 1.3 36.9 10.0 362.8 1.4 1.7 2.0 8.9 6.1 10.7 1.4 2.6 3.1 1.2 3.6 2.8 0.1 8.9 0.0 3.0 2.9 2.1 7.2 1.9 1.6 1.3 57.0 61.9 6.7 6.9 0.0 2.3 10.9 21.8 9.2 2.6 4.7 5.1 2.1 22.8 13.7 3.4 MSTN GDF8 ENSG00000138379 Myostatin O14793 2 190055700-190062729 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 10.1;tongue: 15.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.7;Cone photoreceptor cells: 4.2;Early spermatids: 17.8;Late spermatids: 4.2;Muller glia cells: 19.1" "Cancer enriched" "Detected in some" 9 "glioma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "LHCN-M2: 25.9;RH-30: 52.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009963 Approved "Secreted in other tissues" NA NA 7600000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB009963: AB_2148798" "unprognostic (8.45e-2)" "unprognostic (2.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.54e-1)" "prognostic favorable (2.86e-4)" "unprognostic (7.59e-3)" "unprognostic (2.95e-1)" "unprognostic (4.09e-2)" "unprognostic (1.91e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-3)" "unprognostic (7.72e-3)" "unprognostic (1.12e-4)" "unprognostic (1.06e-1)" "unprognostic (3.94e-1)" "unprognostic (6.53e-2)" "unprognostic (5.67e-4)" 0.4 0.9 0.6 0.0 0.6 0.0 0.3 0.7 0.9 1.2 0.1 0.6 0.2 0.8 0.5 1.1 0.3 0.1 0.3 0.7 0.5 0.5 0.1 0.2 0.0 0.6 0.6 0.4 0.2 0.0 0.6 0.0 0.6 0.4 0.4 3.1 0.4 0.1 10.1 0.5 0.2 0.3 0.4 0.2 0.2 0.3 0.5 0.0 0.4 15.3 0.0 0.2 0.5 0.5 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.9 0.7 0.5 0.6 0.6 0.6 0.4 0.5 0.5 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 17.8 0.1 0.1 0.1 0.0 0.0 1.4 0.2 0.0 1.4 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.0 19.1 0.0 0.5 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 2.0 0.0 0.7 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MTRNR2L1 ENSG00000256618 "MT-RNR2 like 1" P0CJ68 17 22523415-22524663 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 20164.8;choroid plexus: 8845.1" "Cell type enriched" "Detected in many" 11 "Cardiomyocytes: 16283.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4804.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 4804.8" "Cell line enhanced" "Detected in all" "HeLa: 3045.1;Hep G2: 1708.1" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.08e-1)" "unprognostic (4.41e-3)" "unprognostic (2.99e-2)" "unprognostic (9.82e-3)" "prognostic favorable (8.99e-4)" "unprognostic (2.14e-1)" "unprognostic (2.59e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-2)" "unprognostic (1.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.35e-2)" "unprognostic (1.64e-1)" "unprognostic (1.49e-2)" "unprognostic (5.21e-3)" 713.0 996.4 8845.7 173.6 8845.9 274.4 262.3 8845.0 20164.8 111.8 8845.1 625.8 358.0 130.9 204.8 373.7 139.4 196.7 2311.0 9146.7 8845.4 1188.8 941.5 142.9 125.6 9179.3 8845.3 138.8 404.2 616.0 0.0 184.5 9002.4 233.2 536.5 633.2 441.1 281.0 3639.3 418.2 401.8 204.0 8865.7 216.5 445.2 369.7 8847.1 119.8 100.4 3327.7 193.1 177.0 0.0 8862.4 268.9 621.7 231.5 771.3 365.2 150.1 292.9 243.5 59.4 57.5 66.0 386.2 417.6 362.9 260.2 130.7 40.4 685.1 18.1 90.8 71.0 214.7 441.0 331.6 3045.1 1708.1 118.5 77.8 376.1 338.0 191.1 63.1 152.7 407.1 62.9 232.2 276.6 211.5 172.8 222.1 121.7 528.1 65.0 208.0 138.3 196.3 145.4 186.7 321.5 380.3 121.8 215.0 119.2 217.6 376.5 222.6 205.9 551.4 118.8 302.6 251.1 364.1 156.7 196.5 68.6 174.1 169.9 483.3 67.0 2097.9 721.0 1313.4 204.5 325.1 248.2 597.3 255.0 225.8 245.8 585.3 331.9 301.3 4804.8 301.1 339.6 428.7 248.4 677.0 8845.7 8845.9 8845.0 20164.8 9146.7 8845.4 9179.3 8845.3 9002.4 8865.7 8847.1 8862.4 16.2 131.4 117.3 0.0 16.2 84.4 1432.1 2.8 0.0 0.0 54.3 88.4 16283.9 5.7 145.5 77.3 0.0 0.8 3.0 4.0 111.6 0.6 6.6 23.4 4.5 460.8 1.8 0.0 0.0 0.7 0.7 591.3 0.0 56.4 166.5 128.9 4.2 11.9 0.8 0.0 0.0 6.5 0.0 7.2 56.2 17.8 15.5 71.6 62.2 0.0 1.3 0.0 0.0 0.0 0.1 0.3 2.7 4.1 0.5 261.1 1.0 1169.4 101.8 0.0 0.0 346.1 450.7 10.2 18.2 0.0 171.3 1.0 79.5 34.6 2.2 749.7 MTRNR2L10 ENSG00000256045 "MT-RNR2 like 10" P0CJ77 X 55181392-55182442 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "brain: 1196.7" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 9177.9" "Cancer enhanced" "Detected in single" "stomach cancer: 0.6" "Region enriched" "Detected in all" 37 "cerebral cortex: 1196.7" "Group enriched" "Detected in all" 5 "basophil: 171.3;eosinophil: 137.1;neutrophil: 395.3" "Lineage enriched" "Detected in all" 8 "granulocytes: 395.3" "Cell line enhanced" "Detected in many" "A549: 178.6;HeLa: 834.8;Hep G2: 578.6" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (4.42e-1)" "unprognostic (3.04e-2)" "unprognostic (1.15e-1)" "unprognostic (5.10e-4)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (1.71e-2)" "unprognostic (8.42e-2)" "unprognostic (1.58e-2)" "unprognostic (9.01e-2)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (3.01e-1)" "unprognostic (6.28e-2)" "unprognostic (2.97e-2)" "unprognostic (4.99e-2)" "unprognostic (3.97e-4)" 38.3 32.2 18.5 5.8 18.6 8.3 3.7 18.5 1196.7 0.7 18.5 38.9 11.3 12.0 38.4 23.1 17.0 10.6 161.2 32.3 18.5 121.9 79.5 3.4 2.6 28.7 18.6 14.9 23.8 5.1 0.0 6.6 22.3 8.3 66.1 2.4 27.7 3.5 127.9 12.7 10.5 24.6 20.3 8.4 10.7 22.5 18.6 1.0 5.7 15.0 21.2 4.4 0.0 18.9 10.5 178.6 2.4 49.1 4.5 2.2 12.8 16.1 0.8 0.9 0.5 12.1 25.7 24.2 3.4 1.1 2.1 36.6 0.1 1.2 0.5 7.0 36.4 12.3 834.8 578.6 1.1 4.1 6.5 6.2 2.7 0.3 2.0 42.0 0.7 18.4 21.8 13.7 1.9 67.9 3.8 28.8 1.1 0.9 14.0 9.2 9.9 11.3 4.0 111.5 2.5 10.2 4.7 4.3 18.1 23.2 14.4 21.1 25.7 18.0 3.8 6.2 1.6 4.4 3.1 2.0 11.2 5.3 4.0 171.3 50.3 137.1 9.5 25.1 11.4 38.2 14.8 12.7 21.7 36.5 19.1 22.3 395.3 22.8 24.5 26.2 16.2 63.8 18.5 18.6 18.5 1196.7 32.3 18.5 28.7 18.6 22.3 20.3 18.6 18.9 3.8 0.0 0.0 0.0 4.9 8.2 411.9 1.0 0.0 0.0 15.8 6.6 9177.9 2.8 0.6 42.3 0.0 0.3 1.3 0.0 84.1 0.0 0.3 11.5 6.5 296.2 0.0 0.0 0.0 0.0 0.3 289.5 0.0 16.0 0.0 4.0 1.8 6.2 0.6 0.0 0.0 0.0 2.0 5.5 23.2 1.1 0.6 75.9 16.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.5 222.0 0.0 611.6 0.6 0.0 0.0 995.2 385.1 0.6 0.9 0.0 9.1 0.3 70.1 4.3 0.0 449.2 MTRNR2L11 ENSG00000270188 "MT-RNR2 like 11" S4R3Y5 1 237943724-237945275 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 13 "brain: 4100.7" "Group enriched" "Detected in some" 15 "Cardiomyocytes: 1131.8;Proximal tubular cells: 286.7" "Not detected" "Not detected" "Region enriched" "Detected in all" 11 "cerebral cortex: 4100.7" "Group enriched" "Detected in all" 4 "basophil: 95.3;eosinophil: 74.4;neutrophil: 274.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 274.5" "Cell line enhanced" "Detected in many" "HeLa: 302.4;Hep G2: 155.2" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.07e-1)" "unprognostic (9.70e-2)" "unprognostic (4.49e-2)" "unprognostic (5.26e-2)" 76.7 74.6 270.2 11.8 270.2 16.9 12.1 270.2 4100.7 4.2 270.3 48.8 23.6 12.8 7.2 6.7 5.4 3.8 88.5 355.4 270.2 73.9 52.3 7.6 5.5 358.1 270.2 8.6 26.1 25.0 0.0 9.0 302.0 16.1 23.8 40.6 30.9 11.3 324.5 12.5 27.3 9.3 280.2 16.7 33.1 19.9 270.4 4.7 2.4 121.4 8.1 5.8 0.0 271.2 26.2 59.8 27.3 77.1 23.1 5.8 21.8 42.4 3.5 2.4 3.4 25.5 36.7 44.3 26.5 8.4 4.4 77.4 0.9 5.6 2.3 19.5 41.2 44.6 302.4 155.2 7.6 12.6 34.4 23.3 8.1 2.8 10.3 53.2 3.5 28.5 31.8 25.7 7.2 22.3 12.6 42.3 7.4 32.1 10.8 23.6 22.2 18.1 16.4 35.4 10.4 18.2 16.6 19.3 33.0 26.7 23.5 39.1 68.7 30.7 21.6 25.0 12.4 19.4 6.9 17.4 17.0 42.6 7.6 95.3 33.0 74.4 6.0 13.8 6.9 23.9 9.0 8.1 11.9 23.4 12.4 13.3 274.5 12.8 14.4 15.0 8.9 42.9 270.2 270.2 270.2 4100.7 355.4 270.2 358.1 270.2 302.0 280.2 270.4 271.2 0.2 0.0 0.0 0.0 1.2 4.0 26.3 0.3 0.0 0.0 0.8 0.1 1131.8 0.0 0.0 12.9 0.0 0.1 0.1 0.0 46.9 0.0 0.1 0.2 0.1 22.9 0.0 0.0 0.0 0.0 0.1 33.1 0.0 0.2 0.0 0.0 1.1 1.6 0.1 0.0 0.0 0.0 0.0 0.8 9.0 0.1 0.0 3.0 8.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.0 286.7 0.0 0.0 0.0 6.5 25.6 0.3 0.3 0.0 4.0 0.0 1.8 0.1 0.0 17.7 MTRNR2L12 ENSG00000269028 "MT-RNR2 like 12" P0DMP1 3 96617188-96618236 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 125442.5;choroid plexus: 60537.0" "Cell type enriched" "Detected in many" 11 "Cardiomyocytes: 34487.4" "Cancer enhanced" "Detected in all" "stomach cancer: 14.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 23357.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 23357.3" "Cell line enhanced" "Detected in all" "HeLa: 19226.4" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (3.79e-2)" "unprognostic (1.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (9.76e-3)" "unprognostic (1.69e-3)" "unprognostic (1.81e-2)" "unprognostic (7.77e-2)" "unprognostic (3.55e-2)" "unprognostic (2.08e-2)" "unprognostic (4.90e-2)" "unprognostic (9.59e-3)" "unprognostic (1.81e-2)" "unprognostic (2.61e-1)" "unprognostic (2.08e-1)" "unprognostic (1.85e-2)" 7057.6 9488.3 60539.4 1610.0 60538.6 2401.2 2897.2 60547.3 125442.5 1316.1 60537.0 7130.2 3200.8 1495.8 1887.7 3942.3 1591.4 2141.9 24682.6 62534.7 60541.4 11477.3 10961.9 1405.1 1111.1 63276.7 60541.2 1471.0 3698.8 5500.5 0.9 1862.5 61842.9 2592.6 5672.7 5513.6 4076.4 3320.1 36694.8 4024.2 3630.6 2282.8 60728.7 1990.0 5139.8 3848.1 60548.8 1093.2 1305.3 22600.1 1986.4 1741.0 0.7 60592.0 3129.7 3743.3 2766.3 9914.1 4165.4 2220.4 2507.6 3970.8 808.2 749.3 954.5 2070.2 4888.5 6887.0 3132.2 1502.3 436.5 8365.9 196.7 1668.9 1010.6 2008.1 3570.2 7299.3 19226.4 8838.4 1579.3 1469.9 3824.2 4061.3 1945.5 784.9 2127.7 4578.8 844.6 3040.7 5258.3 2276.0 2553.9 1634.8 1252.5 4510.6 808.3 1892.5 1113.4 1992.1 2667.8 2102.8 4420.6 2269.6 1246.8 2408.9 2618.4 2595.6 3524.2 2439.6 2667.3 4152.9 3817.7 3062.1 2505.1 3462.1 1143.3 1197.9 802.7 3365.5 1896.5 8908.3 850.3 10533.0 3473.8 6467.2 1043.1 1696.3 1353.8 2636.4 1309.8 1129.5 1256.2 2611.9 1648.9 1580.6 23357.3 1490.6 1781.5 2078.4 1275.7 2740.2 60539.4 60538.6 60547.3 125442.5 62534.7 60541.4 63276.7 60541.2 61842.9 60728.7 60548.8 60592.0 1081.2 2705.1 2934.5 0.0 291.8 112.5 420.7 10.3 3.4 0.0 702.7 1431.3 34487.4 147.3 1441.4 84.6 0.0 8.4 394.0 24.5 62.6 1.1 19.7 1096.7 707.4 1236.7 4.9 182.7 0.0 1.8 8.6 1698.5 29.6 1465.4 1715.6 334.8 100.3 171.7 12.3 0.0 0.0 7.1 4.1 126.9 333.5 49.0 42.9 633.1 193.9 0.0 29.8 0.0 28.8 0.0 0.0 1.4 8.4 23.0 213.1 337.3 6.6 521.0 1431.8 0.0 46.0 2907.6 1520.5 36.3 39.6 3.3 80.7 10.5 625.8 220.9 5.2 397.1 MTRNR2L13 ENSG00000270394 "MT-RNR2 like 13" S4R3P1 4 116298876-116300320 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.0;choroid plexus: 1.7;skeletal muscle: 1.5" "Cell type enriched" "Detected in some" 20 "Cardiomyocytes: 176.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.5" "Group enriched" "Detected in some" 6 "HeLa: 4.3;Hep G2: 1.8" "Secreted - unknown location" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (6.40e-2)" "unprognostic (2.88e-1)" "unprognostic (2.49e-1)" "unprognostic (1.99e-1)" 0.2 0.6 1.8 0.0 1.8 0.1 0.0 1.8 3.0 0.0 1.7 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.9 1.9 1.8 0.6 0.3 0.1 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 1.8 0.0 0.2 0.0 0.1 0.0 1.5 0.1 0.2 0.0 1.8 0.0 0.1 0.1 1.8 0.0 0.0 1.0 0.0 0.0 0.0 1.8 0.1 0.4 0.0 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 4.3 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.1 1.8 1.8 1.8 3.0 1.9 1.8 1.8 1.8 1.8 1.8 1.8 1.8 0.0 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.0 0.0 0.0 0.0 176.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 3.8 0.0 0.0 0.0 0.8 4.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.7 MTRNR2L3 ENSG00000256222 "MT-RNR2 like 3" P0CJ70 20 57358447-57359498 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.0;skeletal muscle: 1.0" "Cell type enriched" "Detected in some" 49 "Cardiomyocytes: 3203.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 3.0" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in single" "HeLa: 1.1" "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.55e-4)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (8.34e-2)" "unprognostic (2.64e-1)" "unprognostic (1.80e-2)" "unprognostic (9.44e-6)" "unprognostic (2.56e-1)" "unprognostic (6.68e-2)" "unprognostic (5.35e-3)" "unprognostic (1.52e-3)" "unprognostic (7.52e-2)" "unprognostic (5.36e-2)" "unprognostic (4.37e-2)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (2.94e-3)" 0.0 0.1 0.2 0.0 0.3 0.2 0.0 0.5 3.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.3 0.2 0.2 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 1.1 0.0 0.1 0.0 0.1 0.1 0.2 0.3 0.5 3.0 0.4 0.3 0.3 0.3 0.4 0.2 0.3 0.5 0.7 0.0 0.0 0.0 1.0 3.2 32.3 0.3 0.0 0.0 2.4 1.3 3203.4 1.5 0.1 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.1 0.3 0.3 58.4 0.0 2.7 0.0 0.0 0.4 64.9 0.0 0.7 0.0 0.2 2.2 2.6 0.7 0.0 0.0 0.0 0.0 3.9 12.0 0.5 1.5 1.8 7.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 17.7 0.0 10.6 0.1 0.0 0.0 9.2 60.8 0.3 0.7 0.0 3.1 0.5 1.2 0.1 0.0 18.1 MTRNR2L4 ENSG00000232196 "MT-RNR2 like 4" P0CJ71 16 3370979-3372668 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 293.5" "Cell type enriched" "Detected in some" 14 "Cardiomyocytes: 154.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 168.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 168.2" "Cell line enhanced" "Detected in many" "AN3-CA: 48.8;HaCaT: 51.3;HeLa: 88.0" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (8.53e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" "unprognostic (1.80e-1)" "unprognostic (1.05e-1)" "unprognostic (3.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.37e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (6.81e-3)" "unprognostic (1.65e-1)" "unprognostic (2.79e-1)" "unprognostic (1.19e-1)" "unprognostic (9.27e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" 18.0 52.7 25.5 10.8 25.5 9.4 2.4 27.1 54.2 1.1 25.6 14.7 20.7 4.7 2.2 10.8 2.3 3.4 66.0 28.2 25.6 31.8 17.1 5.7 3.8 27.7 25.5 4.8 13.8 1.7 0.3 6.4 26.8 7.3 9.1 7.3 17.0 2.8 293.5 9.7 21.7 3.4 25.7 9.1 19.1 12.2 25.7 0.2 1.8 3.2 3.3 1.4 0.1 26.9 13.8 8.8 2.6 48.8 1.1 1.6 15.0 7.3 0.4 0.9 0.7 4.2 28.7 10.2 14.5 0.4 0.3 51.3 0.1 0.5 0.4 7.8 5.0 9.0 88.0 36.6 0.2 3.0 23.5 1.0 0.7 0.2 0.5 1.1 0.1 1.1 6.9 13.6 1.5 3.0 6.4 23.8 4.0 0.5 1.7 11.6 6.9 9.2 2.1 10.2 5.7 13.0 4.6 11.6 19.1 0.8 16.1 22.7 6.6 15.4 13.5 18.0 5.3 7.1 2.5 9.7 10.6 22.8 3.7 62.3 25.6 72.1 4.9 12.9 5.5 14.3 6.2 6.4 11.1 16.5 6.9 8.7 168.2 8.6 13.4 13.4 7.7 23.3 25.5 25.5 27.1 54.2 28.2 25.6 27.7 25.5 26.8 25.7 25.7 26.9 0.2 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 0.2 0.1 154.2 2.8 0.0 1.8 0.0 0.1 0.1 0.0 3.9 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.1 0.2 0.0 3.3 0.0 0.2 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.5 0.0 0.6 0.7 0.0 0.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.8 0.0 10.4 0.0 0.0 0.0 2.5 3.3 1.0 0.3 0.0 0.3 0.1 0.4 0.1 0.0 1.4 MTRNR2L5 ENSG00000249860 "MT-RNR2 like 5" P0CJ72 10 55599042-55600728 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 2.3" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 27.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 1.2;neutrophil: 1.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.2" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.11e-2)" "unprognostic (1.20e-1)" 0.0 0.1 1.2 0.1 0.9 0.3 0.0 0.5 1.5 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 1.3 1.7 0.1 0.1 0.0 0.2 1.3 1.4 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.6 0.2 0.1 0.0 0.6 0.2 0.1 0.0 2.3 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 1.2 0.2 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 1.2 0.2 0.1 0.1 0.0 0.1 1.2 0.9 0.5 1.5 1.3 1.7 1.3 1.4 1.0 0.6 2.3 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 27.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 MTRNR2L6 ENSG00000270672 "MT-RNR2 like 6" P0CJ73 7 142666272-142667718 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "brain: 1192.8;choroid plexus: 472.8;skeletal muscle: 369.4" "Group enriched" "Detected in many" 10 "Cardiomyocytes: 1037.7;Proximal tubular cells: 454.5" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 169.7;eosinophil: 127.3;neutrophil: 431.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 431.2" "Cell line enhanced" "Detected in many" "HeLa: 194.4;Hep G2: 136.7" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (5.34e-2)" "unprognostic (1.34e-3)" "unprognostic (3.80e-1)" "unprognostic (4.45e-3)" "unprognostic (1.33e-1)" "unprognostic (2.89e-1)" "unprognostic (1.40e-2)" "unprognostic (3.49e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-2)" "unprognostic (6.02e-2)" "unprognostic (1.04e-1)" "unprognostic (3.69e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-2)" "unprognostic (8.07e-3)" 43.9 72.8 472.9 13.7 473.0 11.8 8.8 473.0 1192.8 2.9 472.8 41.4 18.7 11.2 7.1 22.3 7.1 9.5 163.2 527.9 472.9 70.3 52.9 6.5 5.5 508.2 472.9 7.0 27.6 20.7 0.0 11.2 498.0 13.8 27.2 35.9 27.9 8.7 369.4 21.9 30.8 8.7 477.5 14.8 27.2 23.9 473.0 5.5 3.6 76.0 11.6 6.2 0.0 474.1 17.9 29.5 9.8 67.9 11.2 5.7 16.5 18.3 1.7 1.8 3.1 9.7 31.5 15.2 23.0 3.5 1.4 60.6 0.3 3.6 1.6 9.7 11.2 21.3 194.4 136.7 3.7 4.4 21.7 9.8 4.3 1.5 4.8 37.9 1.7 18.1 18.6 22.2 5.4 9.9 8.8 48.3 3.8 9.6 3.5 14.0 8.4 11.6 11.6 25.5 6.5 24.1 4.9 11.4 39.0 14.1 15.9 29.8 21.3 19.3 19.3 23.2 6.4 8.8 4.2 10.4 11.5 26.9 4.8 169.7 49.8 127.3 12.4 26.8 12.2 45.0 15.0 15.0 23.0 36.7 16.4 21.2 431.2 24.8 25.3 22.9 17.2 62.4 472.9 473.0 473.0 1192.8 527.9 472.9 508.2 472.9 498.0 477.5 473.0 474.1 0.8 38.5 47.7 0.0 1.9 6.4 8.5 1.5 0.0 0.0 1.8 1.9 1037.7 0.0 70.7 33.1 0.0 0.5 0.3 0.1 45.0 0.0 0.3 1.8 0.9 32.4 0.0 2.7 0.0 0.0 0.6 67.0 0.0 2.2 55.5 1.1 1.1 2.7 0.7 0.0 0.0 0.1 2.0 1.6 15.9 2.0 2.5 14.8 3.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 0.0 454.5 41.3 0.0 0.0 6.6 54.7 1.0 2.3 0.0 4.4 0.3 8.8 4.3 0.0 5.1 MTRNR2L7 ENSG00000256892 "MT-RNR2 like 7" P0CJ74 10 37601440-37602974 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 2.1" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 188.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.28e-1)" "unprognostic (5.87e-2)" 0.0 0.1 0.4 0.0 0.5 0.1 0.0 0.4 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.1 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 2.1 0.4 0.5 0.5 0.4 0.5 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 188.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.6 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 MTRNR2L8 ENSG00000255823 "MT-RNR2 like 8" P0CJ75 11 10507894-10509186 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 20406.5;choroid plexus: 8122.9;skeletal muscle: 7550.7" "Cell type enriched" "Detected in many" 11 "Cardiomyocytes: 32407.2" "Cancer enhanced" "Detected in many" "stomach cancer: 6.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 3689.6;eosinophil: 2784.3;neutrophil: 9219.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 9219.1" "Cell line enhanced" "Detected in all" "HeLa: 3532.5;Hep G2: 1873.3" "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (6.19e-2)" "unprognostic (1.43e-1)" "unprognostic (6.66e-2)" "unprognostic (3.26e-2)" "unprognostic (3.71e-2)" "unprognostic (3.52e-2)" "unprognostic (2.81e-2)" "unprognostic (3.45e-2)" "unprognostic (5.28e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.90e-1)" "unprognostic (4.59e-2)" "unprognostic (4.59e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-2)" 1000.1 1776.9 8126.4 330.8 8126.2 480.5 249.4 8126.3 20406.5 105.8 8122.9 906.3 612.7 222.9 263.8 642.6 200.9 300.7 3864.2 8509.5 8134.6 1780.1 1280.5 190.2 198.6 8655.4 8131.2 239.2 613.2 509.7 1.3 236.5 8396.6 342.3 741.4 864.6 742.7 271.9 7550.7 621.6 723.9 285.9 8194.3 375.6 681.5 599.0 8130.7 96.8 149.4 1897.1 267.0 201.6 0.6 8143.9 527.3 715.6 334.3 1521.1 294.0 151.4 438.7 562.6 61.4 61.1 75.9 427.1 742.2 698.2 544.0 91.4 54.0 1407.6 10.0 103.2 66.3 307.0 613.3 685.6 3532.5 1873.3 109.4 143.3 625.4 277.5 137.1 58.0 141.0 578.3 54.0 412.8 543.6 353.2 180.7 260.8 202.2 910.4 124.0 222.2 194.5 333.0 287.7 352.4 328.7 447.0 186.5 418.8 248.4 399.0 703.2 282.9 418.6 836.4 416.2 433.8 414.5 508.2 189.6 213.6 116.4 414.1 313.4 1053.0 125.3 3689.6 1275.5 2784.3 319.4 577.0 409.2 944.6 407.8 353.4 445.8 957.8 509.9 480.1 9219.1 466.8 613.2 688.5 439.4 1155.3 8126.4 8126.2 8126.3 20406.5 8509.5 8134.6 8655.4 8131.2 8396.6 8194.3 8130.7 8143.9 649.6 830.1 866.0 0.0 131.5 471.7 1069.8 27.1 1.2 0.0 599.2 1010.1 32407.2 124.4 492.7 57.0 0.0 6.9 118.0 2.1 72.4 0.0 23.1 785.5 473.5 1034.0 0.0 139.8 0.0 0.0 6.9 1450.7 3.1 916.4 543.7 140.3 119.2 384.5 12.8 0.0 0.0 0.5 4.1 129.6 1091.1 52.7 65.6 420.6 723.9 0.0 14.5 0.0 8.2 0.0 0.3 0.1 0.3 44.8 92.0 618.5 0.3 770.4 481.4 0.0 65.7 2750.1 1533.4 30.9 38.2 0.8 488.9 11.2 370.6 42.0 0.5 1232.9 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 614.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 853.2;Intestinal goblet cells: 418.5;Paneth cells: 641.9;Proximal enterocytes: 422.5;Undifferentiated cells: 207.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "OE19: 220.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" 0.8 0.8 0.0 62.0 0.0 0.1 0.5 0.0 0.1 0.8 0.0 304.6 614.6 1.5 0.0 0.8 2.8 47.9 0.1 0.0 0.0 17.5 3.7 0.3 0.4 0.2 0.0 0.0 4.5 0.0 0.1 0.0 0.3 2.1 301.3 0.0 0.0 0.8 0.0 0.1 503.8 10.9 0.0 0.1 35.3 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.1 0.0 0.0 7.4 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.1 6.4 13.6 0.0 0.8 0.2 0.1 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.9 0.1 0.0 0.0 1.0 0.0 220.9 1.1 0.0 0.1 2.7 0.0 0.0 0.3 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 3.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.3 25.8 0.8 0.0 0.0 0.0 0.0 853.2 0.0 24.7 0.9 120.0 1.5 0.4 153.8 0.0 0.1 31.4 0.0 0.0 36.7 6.1 8.9 0.0 0.0 0.0 0.0 0.0 0.2 418.5 0.0 0.3 0.0 4.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.8 641.9 0.7 0.0 1.5 422.5 7.7 10.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 1.5 0.0 207.9 1.4 MUC16 "CA125, FLJ14303" ENSG00000181143 "Mucin 16, cell surface associated" Q8WXI7 19 8848844-8981342 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.2;cervix: 15.9;fallopian tube: 5.9;salivary gland: 6.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 40.3;Club cells: 81.8;Endometrial ciliated cells: 74.3;Glandular and luminal cells: 157.8;Ionocytes: 99.7;Respiratory ciliated cells: 197.4" "Cancer enriched" "Detected in many" 4 "ovarian cancer: 21.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 23.3;HeLa: 45.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB055172, HPA065600" Enhanced "Secreted in other tissues" NA NA 25000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB055172: AB_2148831, HPA065600: AB_2732736" "unprognostic (8.66e-2)" "unprognostic (3.89e-2)" "unprognostic (5.37e-2)" "unprognostic (3.07e-1)" "unprognostic (1.76e-2)" "unprognostic (3.01e-3)" "unprognostic (3.83e-3)" "unprognostic (1.31e-2)" "unprognostic (1.00e-2)" "unprognostic (1.86e-1)" "unprognostic (1.89e-3)" "unprognostic (1.81e-1)" "unprognostic (2.60e-8)" "unprognostic (3.50e-2)" "unprognostic (2.86e-1)" "unprognostic (1.43e-1)" "unprognostic (3.68e-3)" 7.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 15.9 0.0 0.0 0.0 2.1 0.0 0.3 5.9 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 6.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.6 2.8 0.0 0.0 7.7 0.0 0.0 0.0 0.1 0.0 0.0 45.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.5 0.3 0.1 40.3 0.0 0.0 4.1 0.9 3.4 1.5 81.8 0.0 0.0 2.1 0.2 0.0 0.0 0.2 14.3 74.3 14.8 1.2 0.0 0.0 0.4 0.0 0.4 1.0 0.0 157.8 0.0 0.0 0.0 0.1 0.6 0.0 0.4 0.0 99.7 0.3 0.0 16.4 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 197.4 0.0 0.0 0.0 8.6 0.3 0.2 0.0 0.3 3.3 0.6 0.0 0.0 0.7 MUC20 "FLJ14408, KIAA1359" ENSG00000176945 "Mucin 20, cell surface associated" Q8N307 3 195720884-195741123 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.5;kidney: 69.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.2;Ductal cells: 55.5;Ionocytes: 152.5;Respiratory ciliated cells: 66.5;Urothelial cells: 84.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SK-BR-3: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042249 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042249: " "unprognostic (1.85e-1)" "unprognostic (4.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.83e-3)" "unprognostic (2.12e-1)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.41e-1)" "unprognostic (3.99e-4)" "unprognostic (7.66e-2)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.05e-1)" "unprognostic (2.56e-1)" "unprognostic (3.98e-3)" "unprognostic (1.17e-1)" 6.7 5.1 4.3 1.3 5.0 0.9 7.9 7.0 6.7 23.0 3.0 30.0 3.0 5.0 4.5 58.5 20.0 6.4 6.3 3.6 3.4 69.7 21.1 7.9 0.8 4.1 2.7 11.8 16.1 2.0 16.5 0.5 4.0 20.9 7.2 8.1 40.3 1.1 7.0 8.0 14.7 0.8 1.4 6.1 9.8 8.5 4.2 0.8 16.2 1.0 1.4 21.0 26.0 5.0 0.9 0.0 0.2 0.7 0.4 0.0 0.7 0.0 0.2 0.0 0.1 0.0 3.7 0.1 0.7 0.0 0.2 1.5 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.4 0.1 0.7 3.9 0.1 1.0 0.1 1.1 0.1 3.6 1.3 0.4 0.0 28.1 0.2 0.5 0.2 0.0 0.0 0.2 0.8 1.0 0.1 1.3 1.7 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.0 7.0 6.7 3.6 3.4 4.1 2.7 4.0 1.4 4.2 5.0 0.9 35.3 16.7 16.6 0.5 1.8 10.0 6.4 0.6 19.9 3.2 1.5 0.7 14.3 43.7 22.0 35.5 0.1 0.2 53.2 1.9 55.5 0.1 3.5 1.3 1.7 13.8 5.3 7.5 9.9 0.1 1.8 13.3 6.2 1.3 5.3 3.3 7.3 0.5 11.8 7.7 7.3 152.5 1.0 0.8 0.4 5.3 1.1 3.6 1.0 0.0 4.7 0.0 5.0 3.0 12.2 16.9 6.4 1.7 14.2 16.9 3.3 66.5 20.5 0.0 8.8 3.3 1.3 1.3 4.3 1.8 0.0 1.7 1.0 15.2 84.4 MUC4 ENSG00000145113 "Mucin 4, cell surface associated" Q99102 3 195746765-195811973 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 19.2;intestine: 31.1;prostate: 14.8;vagina: 15.0" "Cell type enhanced" "Detected in many" "Club cells: 193.7;Distal enterocytes: 185.1;Gastric mucus-secreting cells: 163.1;Intestinal goblet cells: 193.3;Respiratory ciliated cells: 336.1;Undifferentiated cells: 174.5;Urothelial cells: 319.4" "Cancer enhanced" "Detected in many" "cervical cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 16 "basal ganglia: 3.4" "HPA005895, CAB013536" Approved "Secreted in other tissues" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB013536: , HPA005895: AB_1079427" "unprognostic (4.16e-3)" "unprognostic (1.00e-2)" "unprognostic (6.79e-2)" "unprognostic (1.11e-2)" "unprognostic (3.03e-2)" "unprognostic (5.16e-2)" "unprognostic (5.49e-2)" "unprognostic (2.74e-1)" "unprognostic (3.19e-1)" "unprognostic (4.22e-3)" "unprognostic (6.68e-3)" "unprognostic (5.30e-2)" "unprognostic (2.43e-3)" "unprognostic (3.19e-1)" "unprognostic (6.78e-2)" "unprognostic (3.46e-3)" "unprognostic (9.97e-3)" 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.1 5.4 0.0 31.1 0.0 0.0 0.0 19.2 2.1 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.8 0.0 7.8 0.0 0.0 0.0 3.4 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.2 1.2 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 6.4 15.6 0.3 2.1 0.0 18.5 82.1 0.6 0.0 25.7 2.9 2.5 0.0 193.7 0.0 0.0 0.1 0.3 185.1 0.0 1.6 3.5 6.2 0.2 0.7 16.4 0.0 0.9 5.2 4.3 0.6 163.1 5.1 2.5 0.1 0.0 0.0 0.1 0.0 1.0 193.3 40.7 0.0 0.0 0.7 0.0 1.8 0.0 1.0 0.0 0.0 0.0 0.0 0.2 37.5 64.3 0.4 0.8 12.4 1.1 0.2 336.1 0.0 0.0 0.5 11.1 2.1 1.9 0.4 0.0 0.1 1.2 2.3 174.5 319.4 MUC5AC MUC5 ENSG00000215182 "Mucin 5AC, oligomeric mucus/gel-forming" P98088 11 1157953-1201138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 101 "stomach 1: 185.1" "Cell type enriched" "Detected in some" 248 "Gastric mucus-secreting cells: 10434.9" "Group enriched" "Detected in many" 4 "pancreatic cancer: 25.3;stomach cancer: 61.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "A549: 19.9;OE19: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002774, CAB009395, HPA040615" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002774: , CAB009395: AB_2146854, HPA040615: AB_2677042" "unprognostic (2.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.14e-2)" "unprognostic (1.72e-2)" "unprognostic (2.51e-2)" "unprognostic (4.56e-2)" "unprognostic (6.49e-2)" "unprognostic (2.44e-2)" "unprognostic (1.30e-3)" "unprognostic (8.46e-2)" "unprognostic (5.83e-4)" "unprognostic (1.84e-1)" "unprognostic (9.21e-3)" "unprognostic (4.07e-1)" "unprognostic (1.37e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 185.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 13.5 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 17.4 0.0 0.1 5.4 0.0 0.0 0.1 0.0 2.7 0.0 42.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.8 0.0 2.8 10434.9 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 4.1 0.0 0.0 0.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.1 0.0 30.0 8.9 0.0 0.0 10.0 0.0 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.1 7.9 0.0 0.0 28.1 MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "salivary gland: 2621.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 443.2;Distal enterocytes: 158.4;Intestinal goblet cells: 210.1;Undifferentiated cells: 183.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "OE19: 113.9;PC-3: 120.0" "Not detected" "Not detected" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" NA NA 1300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" 0.1 0.7 0.2 2.0 0.1 0.0 1.3 0.0 0.4 229.4 0.0 58.0 0.1 0.3 0.0 101.0 1.1 221.3 0.1 0.0 0.0 0.1 2.4 7.5 0.0 0.1 0.0 0.1 9.8 0.0 0.4 0.0 0.0 0.6 17.1 0.0 2621.9 0.0 0.3 0.4 2.6 0.6 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.2 0.0 113.9 120.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 2.3 0.0 0.0 6.7 0.6 0.0 6.4 4.3 12.4 443.2 64.0 0.0 0.0 0.1 0.0 158.4 0.0 0.9 0.0 1.4 0.8 0.9 24.5 0.0 0.1 0.0 0.1 1.1 12.8 7.2 4.5 0.0 0.0 1.2 0.2 0.0 0.0 210.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 53.4 0.0 1.4 1.3 0.1 0.2 24.5 0.0 0.0 0.0 3.0 0.0 0.5 1.6 0.0 0.1 0.7 0.1 183.1 1.1 MUC6 ENSG00000184956 "Mucin 6, oligomeric mucus/gel-forming" Q6W4X9 11 1012823-1036718 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "pancreas: 171.2;stomach 1: 409.9" "Cell type enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 278.8" "Group enriched" "Detected in many" 4 "pancreatic cancer: 42.9;stomach cancer: 58.0" "Region enhanced" "Detected in single" "amygdala: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "OE19: 1.7" "Not detected" "Not detected" CAB002165 Enhanced "Secreted to digestive system" NA NA 75000 "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002165: AB_442114" "unprognostic (1.90e-2)" "unprognostic (1.00e-1)" "unprognostic (5.21e-3)" "unprognostic (1.56e-3)" "unprognostic (1.04e-1)" "unprognostic (5.17e-3)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (1.65e-2)" "unprognostic (2.63e-1)" "unprognostic (9.46e-2)" "unprognostic (8.62e-2)" "unprognostic (3.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (4.72e-2)" "unprognostic (5.23e-2)" 0.5 0.2 1.2 0.0 0.6 0.0 0.9 0.3 0.5 26.3 0.0 3.0 15.6 2.1 0.9 5.2 2.5 0.3 0.2 0.8 0.0 2.6 5.4 0.2 0.0 0.0 0.0 0.2 171.2 0.0 0.2 0.0 0.0 4.3 0.0 0.0 0.1 28.0 0.1 0.1 0.1 0.0 0.0 0.3 409.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.3 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 11.3 2.8 1.7 54.3 0.0 9.2 0.0 0.0 0.2 0.1 0.0 12.2 0.1 0.5 0.1 0.1 0.0 0.0 1.2 19.1 0.0 0.1 278.8 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 59.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 MUC7 "FLJ27047, MG2" ENSG00000171195 "Mucin 7, secreted" Q8TAX7 4 70430492-70482997 "Disease related genes, Predicted secreted proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 875 "salivary gland: 26019.1" "Cell type enriched" "Detected in some" 12 "Melanocytes: 12.4" "Group enriched" "Detected in some" 12 "head and neck cancer: 8.1;melanoma: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA006411 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 48: Smooth muscle cells - ECM organization" "HPA006411: AB_1854204" "unprognostic (5.49e-2)" "unprognostic (3.20e-1)" "unprognostic (1.06e-1)" 1.2 5.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 2.1 0.0 0.0 6.6 0.0 0.0 1.0 3.7 0.6 0.0 0.0 0.7 6.5 29.7 0.0 1.9 3.2 0.0 0.8 0.0 0.0 26019.1 0.0 2.6 3.6 1.5 0.0 0.0 1.0 1.1 1.5 0.2 0.0 1.3 0.1 0.4 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 12.4 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MUCL1 SBEM ENSG00000172551 "Mucin like 1" Q96DR8 12 54830518-54896008 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 3241.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4494.5;Breast myoepithelial cells: 1273.2;Melanocytes: 1060.1" "Cancer enriched" "Detected in many" 30 "breast cancer: 298.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;hTCEpi: 1.3;MCF7: 2.1;SK-BR-3: 4.8;SuSa: 3.3" HPA039093 Enhanced "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA039093: AB_10795577" "unprognostic (2.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (8.34e-3)" "unprognostic (5.55e-2)" "unprognostic (2.00e-1)" "unprognostic (3.11e-2)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (9.90e-2)" 35.4 0.4 0.2 1.1 0.4 0.0 3241.2 0.2 0.6 1.3 0.1 1.8 0.0 0.2 1.5 0.4 2.1 0.2 2.6 0.3 0.2 2.3 1.0 1.1 0.1 0.2 0.2 0.3 0.3 0.0 0.3 0.4 0.2 1.1 0.0 0.0 207.3 0.0 1.9 762.2 0.3 0.1 0.2 0.2 0.7 1.2 0.2 2.4 0.2 0.0 0.0 1.2 3.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.8 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.6 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.5 10.4 0.0 1.1 0.0 3.8 188.4 0.4 2.1 0.0 0.0 4494.5 1273.2 0.1 0.0 3.4 0.0 0.0 0.0 12.9 0.0 3.9 0.0 0.0 1.8 0.0 3.4 0.0 0.0 1.4 0.2 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.0 0.0 14.1 0.2 0.0 45.5 1060.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 5.9 0.0 0.1 2.6 0.0 0.0 0.0 6.1 0.2 0.6 0.0 10.1 0.0 2.5 0.1 0.0 3.8 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MXRA7 "FLJ46603, PS1TP1, TMAP1" ENSG00000182534 "Matrix remodeling associated 7" P84157 17 76672551-76711016 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 203.7;Muller glia cells: 365.7;Rod photoreceptor cells: 163.8;Theca cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 663.8" "HPA044819, HPA075316" Uncertain Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA044819: AB_10964134, HPA075316: " "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (2.92e-1)" "unprognostic (1.19e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (4.70e-4)" "unprognostic (3.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-3)" "unprognostic (2.07e-2)" "unprognostic (8.33e-2)" "unprognostic (5.39e-3)" "unprognostic (4.67e-3)" "unprognostic (6.21e-2)" "unprognostic (4.63e-3)" "prognostic unfavorable (1.80e-5)" 189.2 244.3 111.9 53.4 175.1 13.5 133.5 114.5 136.5 149.4 263.7 310.7 37.5 268.3 208.8 157.0 181.0 103.6 526.4 123.4 118.4 83.0 29.9 124.9 31.8 130.3 122.7 185.4 90.3 235.7 48.8 102.8 125.3 154.3 76.1 514.6 62.0 314.8 68.8 73.0 89.4 284.4 122.1 149.7 124.0 115.7 115.4 44.6 272.1 75.9 33.3 250.5 123.1 120.4 19.1 56.1 82.4 155.3 424.0 384.4 41.0 263.8 212.8 188.8 182.8 75.1 2.9 0.5 116.8 368.0 196.8 75.7 92.5 146.5 306.4 1.4 91.7 48.7 39.2 126.8 258.4 22.9 5.9 241.1 171.2 219.3 178.7 421.8 282.0 12.3 35.2 1.2 440.8 5.3 2.9 15.9 26.5 30.0 156.7 43.2 322.2 16.5 153.1 4.8 28.8 207.3 78.5 1.0 152.6 231.6 51.5 29.3 348.5 422.7 90.1 174.3 282.6 24.5 4.9 1.4 663.8 9.9 62.5 1.3 2.8 0.5 4.0 0.8 3.1 2.3 2.1 4.5 2.1 0.4 1.3 2.9 1.1 5.4 0.3 2.4 0.5 3.4 111.9 175.1 114.5 136.5 123.4 118.4 130.3 122.7 125.3 122.1 115.4 120.4 128.3 16.0 14.6 8.5 2.0 10.3 27.0 15.0 13.6 142.0 9.4 42.5 117.3 2.8 10.3 31.3 95.9 1.4 62.6 1.3 1.9 25.5 3.5 48.7 203.7 56.1 6.7 0.8 19.3 4.1 8.1 97.2 2.0 63.9 2.5 64.7 52.5 4.2 3.5 111.0 27.9 7.5 10.2 5.0 13.3 12.4 101.2 7.4 14.2 10.3 1.3 365.7 6.2 15.1 8.9 6.5 0.3 143.3 11.0 21.2 1.6 8.1 10.2 163.8 13.1 132.1 83.6 2.3 10.7 6.0 8.8 0.8 19.7 218.5 1.5 21.1 MYDGF "C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20" ENSG00000074842 "Myeloid derived growth factor" Q969H8 19 4641374-4670362 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 768.1;Plasma cells: 857.6;Syncytiotrophoblasts: 581.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 1043.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041872, HPA046744" Approved "Secreted to blood" NA NA 285000 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA041872: AB_2677718, HPA046744: AB_2679783" "unprognostic (3.14e-1)" "unprognostic (1.32e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.50e-7)" "unprognostic (4.14e-1)" "unprognostic (1.35e-1)" "unprognostic (1.08e-2)" "unprognostic (1.71e-1)" "unprognostic (5.11e-2)" "unprognostic (4.56e-2)" "unprognostic (8.19e-2)" "unprognostic (4.54e-2)" "prognostic unfavorable (4.99e-12)" "unprognostic (4.42e-1)" "unprognostic (3.24e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" 84.7 94.2 42.5 83.8 43.5 92.0 73.2 44.4 48.7 79.1 47.6 81.4 75.7 75.1 114.6 67.5 71.0 44.1 66.3 43.1 48.1 70.8 259.5 91.7 61.9 45.7 44.0 72.1 210.0 41.7 126.1 76.1 45.8 84.2 65.5 13.0 135.6 52.8 24.7 59.3 71.1 52.9 45.5 123.0 94.5 54.5 45.0 30.8 75.4 15.1 45.5 74.3 63.3 50.2 250.5 118.7 74.6 189.8 228.0 190.2 133.0 449.6 378.1 210.8 263.8 194.9 155.8 145.0 206.5 455.4 171.9 122.7 88.6 157.7 121.8 137.7 152.0 87.6 212.7 250.0 353.9 310.9 201.6 159.0 187.8 154.6 292.3 263.0 233.0 78.8 155.4 1043.7 194.9 134.4 83.9 174.1 94.5 235.3 417.1 80.0 126.3 701.0 169.1 114.2 114.1 117.0 151.0 189.1 227.5 64.2 111.4 366.6 268.9 162.8 135.1 449.2 325.9 505.8 229.6 122.2 401.8 405.8 260.1 156.8 216.6 82.6 148.7 232.2 151.6 123.6 118.7 121.1 264.0 101.0 99.8 107.0 13.8 151.5 209.0 426.0 96.3 225.2 42.5 43.5 44.4 48.7 43.1 48.1 45.7 44.0 45.8 45.5 45.0 50.2 134.4 44.8 68.1 4.6 185.1 0.0 160.1 0.0 46.1 31.0 153.8 133.9 6.6 110.1 18.6 77.3 4.2 284.0 135.6 39.8 43.0 355.9 8.7 65.9 168.2 131.9 31.5 55.3 7.3 351.1 768.1 177.0 92.8 158.8 16.4 135.8 126.7 207.3 415.6 26.9 9.6 96.2 0.0 118.8 0.0 12.8 140.5 155.4 0.0 9.4 250.8 51.3 116.4 8.0 10.6 401.8 71.3 91.0 857.6 342.0 182.9 86.8 9.5 32.7 92.1 92.7 157.1 183.2 125.1 64.4 0.0 581.6 84.9 145.5 101.0 260.7 MYOC "GLC1A, JOAG1, TIGR" ENSG00000034971 Myocilin Q99972 1 171635417-171652688 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 110.8" "Cell type enriched" "Detected in some" 6 "Fibroblasts: 244.4" "Cancer enriched" "Detected in many" 6 "melanoma: 13.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA027364 Uncertain "Secreted to extracellular matrix" NA NA 25000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "HPA027364: AB_10602036" "unprognostic (2.02e-2)" "unprognostic (4.65e-2)" "unprognostic (4.44e-2)" "unprognostic (6.29e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-2)" "unprognostic (3.42e-2)" "unprognostic (3.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.94e-4)" "unprognostic (5.35e-2)" "unprognostic (1.87e-1)" "unprognostic (3.87e-2)" "unprognostic (1.24e-1)" 47.1 1.1 0.0 0.0 0.0 0.0 19.2 0.2 0.0 1.8 0.0 13.0 3.5 16.5 4.9 19.6 15.3 1.5 18.3 0.0 0.1 0.2 0.1 7.4 0.1 0.5 0.1 1.3 3.0 0.1 0.2 0.2 0.2 5.3 3.5 0.0 14.0 6.4 33.8 4.7 4.8 2.9 0.0 0.0 50.2 1.4 0.1 14.1 28.7 110.8 0.2 22.6 9.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.1 0.2 0.0 0.1 0.1 12.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.1 3.1 0.0 0.0 0.1 0.0 0.0 244.4 11.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.1 1.0 8.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.6 2.4 0.1 0.0 0.0 0.0 0.0 0.0 15.1 6.3 0.1 0.1 1.1 0.0 0.0 1.1 0.2 0.0 0.0 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248298-106285966 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 580.0;Langerhans cells: 1123.7;Macrophages: 947.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 279.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 279.2" "Cell line enhanced" "Detected in all" "HHSteC: 387.5;U-87 MG: 434.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" NA NA 2140000 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Cell Junctions" "CAB034349: AB_2251220, HPA047776: AB_2680151, HPA057722: " "unprognostic (2.87e-1)" "prognostic unfavorable (4.78e-4)" "unprognostic (5.90e-3)" "unprognostic (1.63e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (8.81e-4)" "unprognostic (2.15e-1)" "unprognostic (2.74e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (3.02e-1)" "prognostic unfavorable (2.49e-6)" "unprognostic (6.83e-2)" "unprognostic (6.96e-2)" "unprognostic (7.76e-2)" "unprognostic (6.44e-3)" 308.5 74.2 14.4 360.5 15.6 312.5 103.3 15.2 35.4 47.3 21.7 62.5 38.5 38.6 6.9 228.2 107.6 113.7 103.1 15.2 20.9 82.9 317.9 218.5 23.2 75.7 24.9 58.4 80.9 25.9 30.1 87.3 30.3 70.1 30.3 17.2 126.0 13.4 135.9 54.1 55.9 48.0 21.3 88.2 102.4 11.7 46.3 15.6 42.2 44.4 39.9 283.3 86.7 21.5 103.6 41.0 14.6 16.8 85.8 95.0 34.4 26.1 194.7 57.0 90.6 25.7 38.7 77.7 78.8 32.1 131.5 58.2 38.8 88.1 93.8 50.5 51.7 35.8 17.2 22.6 387.5 61.3 49.4 94.8 94.2 114.9 115.0 70.6 187.3 32.0 70.5 225.6 68.1 49.4 58.1 19.4 36.6 33.6 59.7 25.8 30.4 147.6 46.2 60.8 33.4 19.3 46.0 61.1 107.9 43.0 25.4 9.4 168.2 75.6 52.9 105.9 51.9 212.1 142.7 115.7 434.3 69.3 105.6 39.6 6.5 16.0 1.8 21.8 2.4 3.9 2.2 2.7 7.0 3.4 2.8 2.2 279.2 4.4 30.5 5.5 7.1 4.8 14.4 15.6 15.2 35.4 15.2 20.9 75.7 24.9 30.3 21.3 46.3 21.5 323.8 131.4 245.7 12.1 78.0 207.6 321.0 105.7 169.0 23.8 184.2 132.0 94.8 197.3 161.4 42.3 12.5 26.2 67.5 105.8 46.9 320.6 12.2 128.0 160.8 192.8 25.1 29.5 25.3 141.3 58.9 239.6 132.0 296.5 188.4 18.8 159.5 580.0 107.0 40.4 28.8 51.9 63.1 390.3 1123.7 6.9 40.4 947.3 161.9 46.9 102.7 22.6 9.2 12.1 22.4 138.1 49.7 31.2 93.7 364.0 112.8 50.7 94.1 30.8 26.3 264.6 185.6 30.5 65.8 98.3 207.8 25.3 110.3 38.4 79.4 334.5 NAPSA "KAP, Kdap, NAP1, NAPA" ENSG00000131400 "Napsin A aspartic peptidase" O96009 19 50358477-50365830 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lung: 1075.5" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 2: 3072.3" "Cancer enriched" "Detected in many" 18 "lung cancer: 249.9" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 8.7" "Group enriched" "Detected in many" 7 "B-cells: 4.3;dendritic cells: 8.7" "Cell line enriched" "Detected in some" 31 "U-698: 42.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009591, HPA045280, HPA047236, HPA047744" Enhanced "Secreted in other tissues" NA NA 1500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 19: Lung - Lung function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB009591: , HPA045280: AB_2679283, HPA047236: AB_2679993, HPA047744: AB_2680143" "unprognostic (5.36e-2)" "unprognostic (4.77e-2)" "unprognostic (1.64e-3)" "unprognostic (1.78e-1)" "unprognostic (1.93e-1)" "unprognostic (4.65e-2)" "unprognostic (1.02e-1)" "unprognostic (8.30e-3)" "unprognostic (2.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.76e-3)" "unprognostic (7.67e-3)" "prognostic favorable (1.21e-4)" "unprognostic (4.08e-4)" "unprognostic (3.29e-1)" "unprognostic (9.83e-3)" "unprognostic (7.26e-5)" 0.4 0.9 0.8 1.6 0.9 0.1 0.5 0.9 0.9 0.7 0.7 0.6 0.4 0.5 2.0 0.4 1.0 0.1 0.4 0.8 0.9 106.3 1.2 1075.5 1.2 0.9 0.8 2.1 1.0 0.2 0.6 0.4 0.9 1.0 0.4 0.4 0.6 1.0 0.2 1.1 1.5 0.1 0.8 1.1 0.9 1.8 1.0 0.4 1.7 0.0 0.5 0.4 0.7 1.1 0.2 0.4 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.3 0.2 0.0 0.5 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.4 1.3 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.7 0.2 0.5 0.2 0.3 0.4 0.6 0.0 0.2 1.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 1.0 0.0 0.2 0.4 42.1 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.9 0.0 4.3 0.2 0.3 2.6 1.7 0.4 0.4 0.5 0.4 0.7 8.7 0.0 1.1 0.8 0.9 0.9 0.9 0.8 0.9 0.9 0.8 0.9 0.8 1.0 1.1 0.3 522.4 3072.3 0.3 3.8 0.1 0.5 0.2 0.0 1.3 0.8 0.9 0.4 1.5 45.9 46.0 4.2 0.5 0.4 0.8 9.8 0.6 47.2 12.6 0.4 6.2 0.0 0.4 0.5 0.8 0.3 5.8 0.5 1.5 69.4 1.0 0.4 0.4 0.3 0.0 0.5 1.0 0.0 1.6 5.3 9.1 0.9 7.9 0.0 1.9 0.2 1.5 1.0 0.0 1.4 0.1 2.3 0.4 0.6 0.4 2.0 276.1 16.4 0.9 0.0 0.3 0.3 1.4 1.4 0.0 0.6 0.1 12.9 0.4 0.9 0.1 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.7;Distal tubular cells: 201.5;Ductal cells: 112.8;Exocrine glandular cells: 100.1;Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 47.1 74.8 61.0 20.9 63.7 22.2 47.9 66.1 69.6 56.8 71.1 62.9 45.5 68.8 88.7 58.0 59.5 26.5 111.1 60.9 64.3 83.8 86.5 43.6 27.0 62.7 64.8 46.5 69.7 104.7 70.0 23.7 61.8 62.5 41.6 17.4 53.9 48.3 71.8 55.8 48.3 39.7 64.7 43.2 67.5 40.8 63.5 30.6 59.8 68.2 34.3 55.0 47.8 70.5 114.2 155.4 43.9 84.4 64.0 43.8 55.5 29.5 62.3 69.5 72.6 130.6 76.8 62.4 113.4 52.5 55.9 111.1 49.4 99.0 47.5 81.2 98.5 58.1 76.2 86.1 75.1 60.0 60.9 44.2 123.7 87.9 81.9 53.4 95.4 104.7 54.7 70.1 71.6 209.6 83.3 98.0 43.1 158.1 118.2 87.7 40.2 212.6 93.0 93.6 114.7 102.9 90.4 172.4 141.6 66.4 178.3 117.5 51.1 45.1 64.8 64.6 70.6 180.1 110.3 53.0 63.1 37.0 70.4 25.4 96.3 52.9 121.2 111.3 121.3 236.2 109.4 124.3 89.1 186.5 122.8 114.9 11.4 141.3 89.1 225.7 110.1 186.6 61.0 63.7 66.1 69.6 60.9 64.3 62.7 64.8 61.8 64.7 63.5 70.5 29.5 41.7 32.9 0.0 14.8 0.0 0.0 0.0 0.0 0.0 87.5 96.0 0.0 0.0 23.5 68.0 0.0 136.7 28.7 0.0 201.5 112.8 0.0 27.3 29.9 18.4 0.0 0.0 0.0 100.1 43.1 27.2 0.0 32.0 5.1 53.5 0.0 0.0 92.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 91.0 0.0 0.0 6.2 0.0 0.0 219.6 11.7 0.0 0.0 0.0 24.5 0.0 0.0 0.0 0.0 81.3 13.4 48.1 0.0 0.0 NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 676.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.1;Leydig cells: 386.8;Paneth cells: 313.2;Peritubular cells: 356.9;Prostatic glandular cells: 293.3;Proximal enterocytes: 413.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 431.7;HSkMC: 305.6;SK-MEL-30: 473.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" NA NA 8100000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" 166.3 27.7 116.1 61.4 115.2 5.7 183.3 90.6 156.0 676.6 125.7 259.3 195.0 253.9 48.3 206.8 281.5 202.6 119.1 147.1 117.1 67.2 5.8 312.0 57.3 101.7 140.7 635.9 27.1 48.3 125.3 21.6 117.0 376.0 109.3 14.5 65.4 113.5 26.6 199.1 314.1 113.0 95.0 25.8 139.9 44.5 109.5 25.3 85.9 28.4 22.4 246.5 373.8 97.3 138.8 42.9 7.2 38.5 431.7 222.7 19.7 195.5 238.6 64.1 64.7 11.8 242.6 0.2 122.2 245.7 44.8 153.4 40.8 180.1 19.6 132.9 23.0 6.8 40.5 72.4 69.4 0.5 3.1 305.6 162.0 94.6 57.6 19.1 48.7 8.0 1.4 0.4 20.6 20.4 0.4 11.7 2.9 142.3 65.2 6.4 0.1 4.7 122.5 16.6 3.1 102.2 31.2 1.2 473.8 7.1 160.2 24.3 68.9 62.4 49.7 180.0 30.3 0.9 1.1 0.8 45.4 0.6 19.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.4 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.1 116.1 115.2 90.6 156.0 147.1 117.1 101.7 140.7 117.0 95.0 109.5 97.3 150.4 3.2 2.3 0.0 2.9 174.6 237.3 22.6 107.0 35.5 41.5 32.8 43.5 55.8 11.9 36.8 6.2 1.0 5.1 395.1 3.9 43.0 2.0 15.6 55.7 84.3 54.5 3.4 0.0 7.7 2.6 241.4 39.8 10.1 13.4 80.9 47.8 1.5 54.6 6.7 0.0 244.6 12.2 2.2 76.6 13.1 386.8 6.6 60.5 0.0 5.8 13.4 0.0 0.0 0.0 97.5 313.2 356.9 1.1 293.3 413.8 19.7 24.5 10.2 131.5 14.0 142.9 1.4 7.6 61.4 202.4 1.4 29.6 15.1 220.4 206.5 NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 290.1;heart muscle: 145.5" "Cell type enhanced" "Detected in many" "Astrocytes: 530.8;Excitatory neurons: 461.4;Inhibitory neurons: 441.2;Oligodendrocyte precursor cells: 939.0;Oligodendrocytes: 1013.5" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.7" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.7" "Cell line enhanced" "Detected in many" "HEL: 61.3;RH-30: 132.5;SCLC-21H: 107.4;SH-SY5Y: 52.7;U-138 MG: 72.8;WM-115: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 1200000 2300000000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" 4.6 65.7 124.0 3.9 169.1 1.5 2.7 118.1 140.3 35.1 0.0 47.8 4.6 62.7 3.5 7.0 40.4 4.8 145.5 135.6 179.1 3.2 2.9 1.8 1.3 140.4 134.2 43.8 2.6 0.0 22.2 0.5 147.4 14.9 6.6 117.7 3.6 17.7 31.2 2.1 18.3 46.9 129.7 4.7 23.0 5.0 137.0 0.4 30.2 29.5 1.0 34.8 24.3 290.1 0.1 0.0 20.8 0.3 0.2 0.5 0.3 1.0 0.0 0.7 1.2 0.3 0.3 3.1 18.2 20.1 0.8 0.3 0.1 0.0 0.0 0.4 12.1 61.3 0.1 0.0 2.1 0.0 9.5 12.4 0.1 0.1 18.6 0.1 0.0 0.1 0.0 1.0 20.8 0.0 0.2 5.2 1.8 0.0 0.4 0.1 132.5 10.0 0.0 0.0 107.4 52.7 0.1 0.5 0.1 2.0 0.2 0.8 0.2 72.8 33.4 0.3 31.8 0.1 0.5 0.1 8.3 28.4 79.0 0.0 0.2 0.0 3.6 0.0 1.2 0.0 0.1 0.5 0.1 0.0 0.0 1.4 0.7 53.7 0.0 0.0 0.2 1.9 124.0 169.1 118.1 140.3 135.6 179.1 140.4 134.2 147.4 129.7 137.0 290.1 13.7 0.0 0.0 530.8 0.4 1.7 0.5 0.0 0.0 123.5 5.7 0.6 131.7 0.0 0.0 0.0 37.5 0.6 27.7 0.1 1.9 18.3 6.7 0.3 2.4 2.8 5.4 0.0 461.4 0.0 0.2 12.8 5.1 0.5 1.3 11.7 7.1 0.7 0.4 175.0 441.2 0.0 8.2 4.7 3.8 5.9 15.2 1.8 0.0 35.6 1.2 216.6 59.8 939.0 1013.5 1.3 0.0 10.1 5.6 0.4 0.0 0.2 0.7 98.0 0.0 107.5 4.8 1.0 2.8 0.4 1.7 0.1 13.4 5.6 0.0 0.2 NCAN CSPG3 ENSG00000130287 Neurocan O14594 19 19211958-19252233 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 63 "brain: 73.6" "Cell type enriched" "Detected in some" 6 "Astrocytes: 195.5" "Cancer enriched" "Detected in some" 57 "glioma: 71.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;SCLC-21H: 2.3;SH-SY5Y: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036814 Enhanced "Secreted in brain" NA NA 790000 "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA036814: AB_10673666" "unprognostic (1.02e-2)" "unprognostic (2.84e-3)" "unprognostic (1.92e-1)" "unprognostic (1.56e-2)" "unprognostic (2.35e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (1.03e-3)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "unprognostic (4.58e-3)" "unprognostic (4.38e-2)" "unprognostic (9.09e-6)" "unprognostic (1.10e-2)" "unprognostic (2.79e-2)" "unprognostic (2.91e-1)" "unprognostic (2.58e-2)" 0.0 0.1 52.8 0.0 53.1 0.0 0.0 15.2 73.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.6 44.2 0.0 0.0 0.0 0.0 33.3 32.3 0.0 0.0 0.0 0.3 0.0 38.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 21.5 0.0 0.0 0.9 61.5 0.1 0.0 0.0 0.0 0.0 0.0 49.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.8 53.1 15.2 73.6 55.6 44.2 33.3 32.3 38.1 21.5 61.5 49.4 0.0 0.0 0.0 195.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 15.5 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 8.4 0.0 0.5 0.0 29.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Bipolar cells: 69.8;Early spermatids: 217.1;Late spermatids: 221.7" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 48.5;U-266/70: 20.8;U-266/84: 85.8" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" 4.8 2.6 1.1 0.9 1.7 0.0 3.2 4.7 1.2 14.2 9.3 6.5 2.9 6.0 4.3 7.7 20.4 9.4 5.2 1.8 2.6 27.1 0.4 106.5 0.3 8.8 12.9 42.5 0.5 0.7 5.3 60.1 15.2 16.7 8.3 57.4 2.2 4.4 4.3 1.7 4.7 3.5 7.6 0.3 4.1 10.4 3.7 2.4 1.3 14.0 0.2 9.0 1.9 5.4 0.2 0.0 10.6 0.0 13.9 11.3 0.2 0.2 0.5 0.2 0.5 1.6 0.0 0.0 0.0 48.5 0.8 0.0 0.0 0.0 1.1 0.9 1.7 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.6 0.0 0.0 0.0 14.3 1.0 0.0 0.2 0.1 0.9 7.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 2.6 0.2 0.0 0.0 11.5 0.0 0.2 0.5 20.8 85.8 0.0 3.9 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 4.7 1.2 1.8 2.6 8.8 12.9 15.2 7.6 3.7 5.4 10.9 246.8 48.3 1.6 0.0 1.1 0.0 0.0 0.0 69.8 0.2 0.1 1.6 8.6 28.6 12.9 18.8 0.3 0.0 5.3 0.0 0.0 217.1 0.9 4.7 11.7 1.8 0.0 0.0 0.2 0.0 14.9 0.0 0.1 2.5 0.1 2.9 0.0 0.1 1.7 8.0 0.8 0.0 0.0 0.8 221.7 3.4 0.4 5.4 6.5 0.0 12.2 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.0 12.5 20.0 0.0 1.2 3.6 6.4 5.0 0.3 0.9 0.5 0.3 13.0 1.2 0.1 NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;ovary: 46.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 181.3;Muller glia cells: 105.5" "Cancer enriched" "Detected in many" 5 "glioma: 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-87 MG: 72.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA003095: AB_1079457" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-3)" "unprognostic (6.84e-3)" "unprognostic (1.51e-1)" "unprognostic (9.09e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" 0.5 0.0 31.5 0.0 33.4 0.0 3.3 30.9 35.8 20.9 22.4 0.2 0.1 15.4 22.0 0.0 20.8 0.4 0.3 31.5 29.6 0.1 0.0 0.0 0.2 30.1 33.2 46.2 0.0 0.2 0.1 4.0 31.6 7.1 0.2 19.2 0.1 13.1 0.0 0.6 0.2 11.4 32.4 0.1 0.3 1.0 34.2 0.0 0.2 0.0 0.2 0.5 2.3 32.4 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.1 1.9 0.0 0.0 0.0 1.8 0.0 4.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 2.2 0.0 0.0 0.0 72.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 33.4 30.9 35.8 31.5 29.6 30.1 33.2 31.6 32.4 34.2 32.4 0.0 0.0 0.0 29.0 0.0 0.1 0.0 1.2 0.0 0.6 1.3 0.1 0.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 2.0 0.0 9.1 17.7 0.2 0.0 0.0 4.2 0.0 0.3 0.9 0.0 17.0 0.0 181.3 0.0 0.0 0.1 0.0 0.8 0.0 2.0 0.0 0.0 0.7 13.4 0.6 0.0 0.0 0.0 105.5 0.0 1.5 9.5 1.2 0.0 9.8 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 5.4 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 128.8;skin 1: 134.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 12.1;Breast myoepithelial cells: 27.3;Exocrine glandular cells: 12.3;Granulosa cells: 68.7;Pancreatic endocrine cells: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 229.2;hTCEpi: 139.2;RT4: 157.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" NA NA 180000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "CAB016135: AB_626865, HPA026846: AB_1846226" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.25e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (3.42e-1)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.59e-3)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.62e-2)" 4.4 4.0 14.8 4.7 25.6 24.3 8.2 17.4 32.3 14.0 0.0 12.4 16.6 3.4 2.3 128.8 4.0 3.4 8.1 30.5 15.3 5.1 4.3 3.4 2.1 23.8 26.5 2.3 18.8 2.7 7.8 7.3 18.4 12.8 12.9 18.5 18.0 6.2 1.9 134.4 12.0 4.5 16.3 3.3 4.6 1.3 26.9 6.7 2.2 1.6 27.9 28.9 36.8 38.8 16.6 13.6 12.6 18.2 6.5 2.1 88.2 6.6 6.1 5.4 3.8 28.8 55.2 21.8 26.1 7.6 10.9 229.2 32.5 117.6 2.4 51.8 4.9 3.0 4.4 13.2 2.6 14.9 35.4 2.0 139.2 17.1 62.5 2.1 16.3 6.2 0.6 113.2 7.2 42.7 0.3 9.0 41.6 55.3 18.7 1.2 75.7 26.3 5.1 157.4 30.6 68.6 22.1 57.4 1.8 18.8 52.3 2.2 9.0 4.8 17.6 39.2 5.9 20.6 28.0 0.2 1.7 11.9 11.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 1.6 0.0 0.0 14.8 25.6 17.4 32.3 30.5 15.3 23.8 26.5 18.4 16.3 26.9 38.8 4.2 0.0 3.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 12.1 27.3 0.0 0.0 4.3 1.8 0.0 4.1 4.1 0.0 0.0 8.7 0.0 4.6 3.2 1.3 0.0 0.0 0.0 12.3 1.3 2.1 0.0 10.9 0.0 68.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.5 0.0 0.0 1.9 0.0 0.0 3.3 1.5 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 8.9 1.3 1.7 0.0 0.0 NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.9;skin 1: 113.6;vagina: 57.3" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 384.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 56.5;HaCaT: 37.0;MCF7: 24.0;OE19: 24.6;SK-BR-3: 47.8;T-47d: 31.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" No No 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" 0.4 0.1 0.1 0.5 0.1 0.7 13.7 0.3 0.2 26.5 0.0 1.5 0.7 1.2 6.9 98.9 2.9 3.8 0.1 0.1 0.0 3.1 0.1 3.5 0.1 0.1 0.1 0.0 4.5 0.4 0.6 12.2 0.1 9.4 1.7 0.1 33.6 4.3 0.6 113.6 0.6 0.1 0.0 0.0 8.8 0.6 0.3 0.8 0.2 0.0 14.5 16.8 57.3 0.4 10.9 0.4 0.0 0.1 0.0 0.1 56.5 0.1 0.1 0.1 0.2 0.0 14.6 0.0 0.2 0.0 0.1 37.0 0.0 1.2 0.2 0.0 0.5 0.0 0.8 11.1 0.0 0.1 0.7 0.0 14.6 3.0 3.6 0.1 0.0 0.0 0.0 0.1 0.1 24.0 0.1 0.1 0.1 24.6 0.0 0.0 0.0 0.1 0.0 17.5 0.0 0.2 0.2 47.8 0.0 6.4 31.1 0.0 0.0 0.1 2.4 0.5 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.2 6.4 9.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.6 17.8 0.0 0.0 8.1 16.5 0.0 39.4 0.4 0.0 0.0 41.7 0.0 28.1 2.9 0.6 0.0 0.0 0.0 30.0 67.1 1.2 0.0 43.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 67.1 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 384.2 0.4 0.1 0.0 0.0 NELL1 "FLJ45906, IDH3GL" ENSG00000165973 "Neural EGFL like 1" Q92832 11 20669551-21575686 "Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.2;kidney: 16.6" "Group enriched" "Detected in some" 9 "Excitatory neurons: 279.0;Inhibitory neurons: 175.8;Oligodendrocyte precursor cells: 323.2" "Cancer enhanced" "Detected in many" "melanoma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "OE19: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051535 Approved "Secreted in other tissues" NA NA 160000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA051535: AB_2681524" "unprognostic (1.73e-1)" "unprognostic (1.31e-1)" "unprognostic (7.29e-2)" "unprognostic (5.35e-4)" "unprognostic (3.78e-4)" "unprognostic (1.67e-2)" "unprognostic (3.91e-1)" "unprognostic (4.38e-2)" "unprognostic (4.65e-2)" "unprognostic (1.57e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (7.27e-3)" "unprognostic (4.23e-2)" "unprognostic (1.83e-1)" "unprognostic (2.29e-1)" 0.3 0.1 4.5 0.1 5.5 0.0 0.0 0.0 8.2 0.3 0.0 0.2 0.0 0.3 1.6 0.6 0.1 0.4 0.0 10.2 2.0 16.6 0.0 0.4 0.0 2.4 1.9 0.1 0.0 0.0 3.5 0.0 2.5 5.1 0.3 0.8 0.4 2.5 0.0 0.6 0.1 0.1 0.0 0.1 0.6 1.0 1.5 1.2 0.0 0.3 0.7 0.1 0.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 28.6 0.0 0.0 0.7 0.0 0.0 0.1 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 5.5 0.0 8.2 10.2 2.0 2.4 1.9 2.5 0.0 1.5 4.2 0.1 0.0 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.8 0.7 0.0 0.0 1.8 0.0 0.8 0.0 0.0 5.9 0.0 28.8 0.8 0.1 0.0 0.0 0.0 279.0 0.0 0.0 0.2 0.0 0.0 3.8 0.0 0.0 0.0 0.1 0.0 175.8 0.0 0.0 0.0 0.0 22.3 0.3 0.0 0.0 13.1 0.0 0.0 0.0 323.2 7.6 0.0 0.0 0.0 0.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.2 0.5 0.0 0.0 0.7 0.1 0.0 0.0 0.2 NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.5;choroid plexus: 59.5;fallopian tube: 60.1;retina: 85.2" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 652.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Group enriched" "Detected in many" 15 "amygdala: 48.9;basal ganglia: 60.0;cerebral cortex: 105.5;hippocampal formation: 89.6;white matter: 42.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.4;naive CD8 T-cell: 111.1" "Lineage enriched" "Detected in many" 10 "T-cells: 111.1" "Cell line enhanced" "Detected in some" "AF22: 104.6;HEK 293: 27.5;NTERA-2: 41.2;SCLC-21H: 75.6;U-266/70: 27.5;U-266/84: 29.5;U-698: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" NA NA 6400000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" 4.6 16.9 48.9 10.9 60.0 7.3 1.9 1.3 105.5 23.1 59.5 2.0 26.3 2.2 0.4 1.2 60.1 1.9 0.4 89.6 4.5 1.2 1.0 5.0 20.7 0.0 0.0 0.8 0.9 0.2 34.6 0.3 0.0 27.2 2.1 85.2 1.4 2.0 0.3 13.4 15.3 2.8 0.0 6.2 2.9 3.0 0.8 8.7 6.5 0.6 15.7 4.1 4.2 42.0 0.3 0.1 104.6 3.5 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 8.3 12.4 0.0 0.0 0.2 25.3 0.2 0.0 0.0 27.5 0.4 8.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.1 1.6 0.2 0.4 0.0 0.4 0.2 0.4 41.2 0.0 14.0 0.2 12.7 0.2 0.0 0.0 75.6 1.8 0.0 0.4 0.0 1.3 0.1 0.7 0.0 0.4 3.8 0.1 2.1 27.5 29.5 40.3 0.2 0.2 0.4 0.2 0.2 0.0 5.0 0.1 24.9 0.2 30.3 52.9 0.1 0.1 70.4 111.1 0.5 11.0 0.1 0.1 0.4 26.7 48.9 60.0 1.3 105.5 89.6 4.5 0.0 0.0 0.0 0.0 0.8 42.0 0.3 0.0 1.3 48.0 1.0 1.1 0.0 0.0 5.7 35.4 0.4 0.6 0.5 2.8 6.2 0.0 33.3 0.1 2.5 5.8 0.0 0.0 0.4 0.7 0.8 0.7 0.0 0.0 652.4 0.2 0.3 3.7 0.0 0.3 0.0 49.4 0.0 0.0 0.1 1.7 108.4 0.9 0.0 0.0 1.5 1.0 0.0 0.4 0.0 18.7 1.3 7.9 1.0 74.4 16.5 0.4 0.4 0.4 0.5 0.3 18.5 0.2 21.9 58.3 0.0 4.1 4.6 1.9 4.2 0.2 1.1 0.1 23.4 0.1 2.9 0.1 NENF "CIR2, SCIRP10, SPUF" ENSG00000117691 "Neudesin neurotrophic factor" Q9UMX5 1 212432920-212446379 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026763, HPA028488" Uncertain "Secreted to blood" NA NA 4000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA026763: AB_1854379, HPA028488: AB_2672638" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" "unprognostic (7.24e-2)" "unprognostic (7.41e-3)" "unprognostic (3.80e-3)" "unprognostic (5.35e-2)" "unprognostic (1.70e-2)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.54e-6)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (4.28e-1)" "unprognostic (2.28e-2)" 63.9 53.4 132.2 16.8 149.0 26.9 65.7 141.3 188.1 82.8 137.7 53.8 19.8 59.8 70.2 45.9 58.3 23.9 141.0 130.9 138.5 70.0 62.7 45.4 16.4 142.5 142.7 82.7 68.7 64.1 148.1 29.4 143.2 69.4 36.1 22.7 72.4 50.5 95.0 55.6 35.2 44.7 142.7 33.6 47.7 16.7 138.3 23.0 57.6 104.5 25.6 58.0 57.7 156.0 78.8 65.3 26.6 103.2 155.3 116.6 38.9 39.5 94.5 67.5 65.7 74.0 49.8 36.0 29.0 93.0 68.4 49.7 55.1 56.0 55.1 45.7 107.2 26.5 39.9 24.4 59.3 25.1 66.2 83.9 82.5 47.8 40.0 76.1 44.1 54.1 60.2 39.0 60.5 40.2 45.4 95.3 39.0 73.9 137.9 42.1 62.6 50.2 70.3 23.1 43.2 77.5 59.2 89.6 74.0 40.4 70.8 75.2 9.1 54.9 49.0 76.8 73.3 36.2 62.6 26.9 57.5 36.0 43.0 0.9 4.8 2.1 3.9 7.1 6.9 8.1 4.7 8.8 7.8 5.3 6.1 6.2 0.5 0.9 5.0 13.5 5.8 2.5 132.2 149.0 141.3 188.1 130.9 138.5 142.5 142.7 143.2 142.7 138.3 156.0 124.8 12.8 21.6 14.0 72.0 166.2 233.0 10.8 173.6 44.0 322.5 418.5 152.9 163.0 13.4 248.3 12.5 291.4 64.3 101.0 164.4 50.9 5.3 40.7 119.1 87.4 135.8 135.0 11.9 49.0 182.0 219.7 65.7 58.4 47.1 45.7 145.3 211.8 189.3 38.7 12.6 143.7 6.1 149.4 198.1 23.9 297.6 127.2 186.7 11.2 69.2 329.6 34.0 21.6 80.5 32.7 70.7 223.8 136.0 322.9 56.1 512.7 7.6 28.4 118.3 162.1 233.9 13.3 138.5 158.8 170.6 184.4 70.4 61.8 157.0 264.5 NETO1 "BCTL1, BTCL1" ENSG00000166342 "Neuropilin and tolloid like 1" Q8TDF5 18 72742314-72868146 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 21.9;retina: 34.6" "Group enriched" "Detected in some" 14 "Bipolar cells: 206.4;Excitatory neurons: 307.1;Inhibitory neurons: 345.9;Oligodendrocyte precursor cells: 172.4" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Group enriched" "Detected in many" 41 "amygdala: 6.6;basal ganglia: 12.4;cerebral cortex: 21.9;hippocampal formation: 17.5;white matter: 16.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 21.9;REH: 20.6;RPMI-8226: 32.7;RT4: 24.7;SCLC-21H: 26.9;U-2 OS: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064630 Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA064630: AB_2685305" "unprognostic (4.02e-2)" "unprognostic (4.08e-3)" "unprognostic (2.75e-1)" "unprognostic (1.55e-2)" "unprognostic (6.04e-2)" "unprognostic (1.35e-5)" "unprognostic (4.05e-1)" "unprognostic (4.73e-2)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (3.70e-2)" "unprognostic (3.35e-2)" "unprognostic (1.59e-1)" "unprognostic (9.13e-3)" 1.2 0.0 6.6 0.3 12.4 0.1 1.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 17.5 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.1 34.6 0.2 0.0 0.0 0.3 0.5 0.0 0.0 3.1 0.2 0.8 0.2 0.4 0.6 0.0 1.2 0.1 0.0 16.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 8.7 0.0 0.0 20.6 0.0 32.7 4.0 24.7 26.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 12.4 0.0 21.9 17.5 0.0 0.3 0.0 0.3 0.0 0.2 16.3 2.0 0.0 0.0 16.6 6.1 0.0 0.0 0.0 0.0 206.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 307.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 345.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 2.2 0.0 172.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NGF NGFB ENSG00000134259 "Nerve growth factor" P01138 1 115285904-115338770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.8;ovary: 18.9" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 15.7;Leydig cells: 29.2;Sertoli cells: 118.3;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in many" "renal cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 87.9;BJ hTERT+ SV40 Large T+: 30.1;GAMG: 46.2;hTEC/SVTERT24-B: 29.8;hTERT-RPE1: 49.0;U-2197: 60.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted in other tissues" NA NA 40000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.55e-2)" "unprognostic (2.66e-2)" "unprognostic (1.53e-3)" "unprognostic (8.85e-2)" "unprognostic (4.12e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (5.30e-2)" "unprognostic (8.73e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.08e-7)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (7.99e-3)" "unprognostic (1.62e-4)" 13.9 2.5 1.7 1.6 1.7 0.0 4.0 1.3 2.1 7.1 2.1 5.0 0.1 8.8 1.4 1.1 13.2 1.7 20.8 1.6 2.2 6.4 4.0 1.6 0.5 1.9 1.7 18.9 0.8 0.4 2.7 1.1 1.9 2.6 0.6 0.1 2.1 1.0 0.9 0.9 2.1 4.0 1.4 3.7 2.1 1.1 1.9 0.2 3.3 1.1 0.1 5.5 5.0 1.6 0.0 0.3 0.0 0.0 1.8 0.1 0.0 87.9 9.9 30.1 21.9 0.0 0.0 0.0 1.9 21.1 46.2 3.6 0.0 0.6 13.8 0.0 0.2 0.0 0.6 0.0 12.1 0.0 0.0 0.1 0.6 29.8 21.6 49.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 3.0 0.0 1.3 0.0 1.2 0.0 0.0 0.0 1.1 0.3 1.6 0.6 0.0 3.9 0.0 0.0 0.8 1.8 3.7 60.0 3.5 0.0 0.0 0.0 3.6 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.3 2.1 1.6 2.2 1.9 1.7 1.9 1.4 1.9 1.6 0.4 0.0 0.0 0.3 0.0 3.1 0.5 3.9 0.0 0.0 0.1 1.5 0.7 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 5.6 0.2 0.2 0.8 0.8 0.0 0.0 0.3 0.0 1.3 7.3 0.0 0.3 0.0 0.0 4.2 0.0 0.1 0.0 15.7 0.0 2.0 0.0 1.7 0.4 29.2 0.2 1.8 1.9 0.0 0.0 0.0 12.1 0.5 0.1 0.0 6.0 0.0 0.6 0.0 0.0 0.1 0.0 118.3 0.8 51.6 0.3 1.0 0.0 2.3 2.5 0.6 0.0 0.0 0.3 NHLRC3 ENSG00000188811 "NHL repeat containing 3" Q5JS37 13 39038306-39050109 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013738 Uncertain "Secreted to blood" NA NA 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "HPA013738: AB_1854455" "unprognostic (7.92e-2)" "unprognostic (3.51e-2)" "unprognostic (5.96e-2)" "unprognostic (3.90e-1)" "unprognostic (2.92e-2)" "unprognostic (1.22e-1)" "unprognostic (2.99e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-1)" "unprognostic (8.88e-2)" "unprognostic (2.28e-2)" "unprognostic (4.83e-2)" "unprognostic (3.21e-1)" "unprognostic (1.58e-2)" "unprognostic (2.99e-2)" "unprognostic (1.66e-1)" "unprognostic (7.81e-2)" 18.5 12.0 7.8 10.9 8.6 7.4 15.2 7.6 10.5 12.1 9.7 12.9 11.6 13.5 20.6 7.4 10.7 13.0 10.2 7.9 8.5 16.7 25.9 13.9 14.3 10.1 8.1 15.8 13.4 8.4 11.4 19.4 9.5 11.0 16.6 12.9 12.2 9.8 10.8 12.0 12.3 11.8 8.6 16.1 16.7 8.7 8.5 8.1 16.9 10.4 12.0 10.1 9.8 10.4 5.1 3.1 13.5 6.5 15.4 16.0 20.9 7.8 9.7 8.2 10.9 9.8 22.6 13.9 14.5 5.2 10.3 10.5 5.4 4.5 7.1 20.3 5.8 11.1 6.9 11.2 9.8 11.1 15.8 13.0 5.8 5.7 5.5 12.3 5.2 11.2 4.0 16.9 7.6 3.8 8.7 17.2 3.7 11.8 3.2 9.2 36.2 7.8 12.6 10.1 3.1 5.6 5.0 6.9 18.4 7.5 9.0 17.5 6.0 11.2 5.4 14.7 8.3 13.5 12.3 5.5 14.9 11.9 8.2 1.5 6.8 0.8 4.5 6.9 5.0 4.1 3.2 3.7 6.0 3.0 3.3 4.8 0.6 4.5 6.8 5.4 4.1 3.7 7.8 8.6 7.6 10.5 7.9 8.5 10.1 8.1 9.5 8.6 8.5 10.4 20.6 12.8 20.2 22.9 36.7 8.4 16.9 40.8 15.9 70.8 22.2 13.5 13.0 18.6 35.8 35.0 56.3 78.4 52.5 22.5 9.8 21.0 6.7 14.1 25.3 22.4 13.8 23.3 37.4 16.5 14.9 21.8 17.9 14.6 15.8 76.7 42.5 34.5 43.6 79.1 45.8 28.6 42.7 57.6 27.0 4.6 61.2 35.2 17.8 27.2 47.7 33.5 102.0 40.2 131.7 17.2 25.0 41.8 30.7 10.2 34.8 16.3 32.1 93.1 59.2 14.2 18.7 51.1 41.0 9.0 8.9 24.2 30.5 50.2 28.4 11.7 NID1 "entactin, NID" ENSG00000116962 "Nidogen 1" P14543 1 235975830-236065109 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 230.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 362.9;Fibroblasts: 137.6;Hepatic stellate cells: 191.3;Leydig cells: 177.3;Peritubular cells: 125.6;Sertoli cells: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 5.7;intermediate monocyte: 11.2;myeloid DC: 4.4;non-classical monocyte: 7.3" "Group enriched" "Detected in many" 18 "dendritic cells: 4.4;monocytes: 11.2" "Cell line enhanced" "Detected in many" "ASC diff: 1569.3;ASC TERT1: 726.8;HSkMC: 619.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010044 Approved "Secreted to extracellular matrix" NA NA 150000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "CAB010044: AB_2153287" "unprognostic (1.17e-1)" "unprognostic (2.23e-3)" "unprognostic (3.24e-1)" "unprognostic (2.35e-1)" "unprognostic (4.03e-1)" "unprognostic (2.79e-2)" "unprognostic (2.44e-3)" "unprognostic (1.42e-2)" "unprognostic (7.88e-2)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (5.38e-8)" "unprognostic (3.64e-3)" "unprognostic (1.35e-1)" "unprognostic (7.36e-2)" "unprognostic (3.72e-3)" 110.0 35.5 4.1 30.5 6.8 2.6 88.9 3.4 7.4 78.9 8.8 95.9 21.7 87.6 21.3 26.8 88.1 66.2 53.7 3.8 4.3 28.4 76.9 56.4 12.3 4.2 4.0 77.7 18.3 12.6 10.4 230.9 3.9 33.1 21.3 2.0 17.3 40.2 25.1 24.6 61.0 79.8 3.9 38.0 67.0 6.2 5.3 5.4 27.6 26.9 6.1 62.9 53.4 3.8 1.2 5.3 55.3 0.1 1569.3 726.8 106.2 128.1 105.3 78.0 50.7 30.5 39.8 0.0 25.0 191.2 21.3 4.5 36.3 0.4 45.2 0.2 61.3 8.1 5.9 46.3 295.6 0.0 0.7 619.5 5.3 38.2 1.5 30.3 165.7 0.0 0.0 0.0 26.9 0.0 0.1 0.3 56.9 0.0 6.7 0.0 0.1 0.1 0.0 16.6 0.3 47.0 1.0 0.0 10.2 21.3 0.1 52.1 146.5 67.5 44.8 0.1 57.4 0.1 0.0 0.1 0.8 0.0 105.4 0.2 5.7 0.0 0.0 11.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.4 0.1 7.3 0.0 0.0 2.1 4.1 6.8 3.4 7.4 3.8 4.3 4.2 4.0 3.9 3.9 5.3 3.8 48.7 3.2 1.5 18.9 1.7 6.0 1.3 1.5 0.0 0.2 1.2 2.0 24.0 10.0 2.0 0.0 0.0 13.5 0.6 0.0 0.0 0.5 1.4 11.5 362.9 49.4 0.0 5.3 0.6 0.9 10.2 137.6 0.5 9.6 1.3 2.1 191.3 73.4 8.0 3.3 3.3 0.0 10.2 15.1 19.3 5.7 177.3 9.9 17.8 30.0 10.0 2.2 1.0 1.0 0.3 4.3 0.0 125.6 0.0 5.3 0.0 8.6 0.1 0.1 243.3 18.7 92.3 0.8 0.2 0.8 5.3 15.7 2.9 5.7 0.1 7.3 NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 31.0;Endothelial cells: 19.7;Fibroblasts: 46.0;Microglial cells: 19.7;Smooth muscle cells: 22.6;Theca cells: 19.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 285.4;ASC TERT1: 113.0;BJ: 152.1;BJ hTERT+: 131.8;HHSteC: 158.1;HSkMC: 591.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" 28.3 5.2 0.9 9.2 1.2 0.7 9.6 0.6 1.4 7.5 44.0 8.8 2.3 17.4 5.8 5.4 6.7 19.0 15.6 1.4 0.5 4.8 5.9 6.1 3.5 1.8 0.6 18.9 3.4 13.2 2.5 60.8 0.5 8.4 6.8 0.1 3.6 10.4 4.3 1.7 3.5 11.4 1.1 1.9 6.8 1.4 0.9 2.1 31.6 5.5 1.4 15.4 5.4 1.6 0.0 3.4 76.6 0.0 285.4 113.0 0.2 152.1 131.8 14.5 15.0 0.4 0.0 0.0 22.2 17.3 0.0 10.7 9.9 0.1 3.9 0.1 2.0 0.0 3.0 0.0 158.1 0.0 0.0 591.5 0.0 59.6 0.1 82.5 8.1 0.1 0.0 0.0 8.6 0.0 0.0 0.4 3.3 0.0 5.1 23.5 0.2 0.1 19.9 0.0 0.0 1.8 0.0 0.1 0.0 10.0 0.0 0.0 0.9 54.4 0.6 33.0 0.0 0.0 0.0 0.1 17.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.6 1.4 1.4 0.5 1.8 0.6 0.5 1.1 0.9 1.6 31.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.6 1.4 0.2 0.3 2.1 0.0 0.0 1.8 0.0 0.7 0.7 3.7 0.0 0.1 14.0 1.5 11.3 19.7 0.0 0.0 0.8 0.0 1.1 46.0 1.1 0.4 1.3 0.4 8.6 0.0 1.6 0.0 1.7 2.0 0.0 0.3 1.2 4.4 6.2 0.3 3.6 19.7 1.0 0.0 0.0 2.0 4.8 0.2 1.3 8.6 0.1 0.2 1.7 0.4 0.0 0.8 6.6 6.1 22.6 0.2 0.1 0.1 1.0 0.8 0.4 19.1 3.0 0.2 NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 68.3;brain: 58.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 319.5;Club cells: 164.2;Ductal cells: 123.9" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 90.1" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.0" "Group enriched" "Detected in all" 5 "olfactory bulb: 43.3;pons: 14.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" 68.3 24.0 19.9 4.1 17.9 6.0 30.7 18.2 23.5 8.3 16.3 5.3 3.1 7.5 4.9 6.9 8.6 4.8 5.4 21.4 58.9 10.7 3.1 6.2 5.7 29.3 22.7 7.1 8.4 4.5 9.8 1.9 26.2 5.0 2.9 3.0 7.4 2.5 2.5 4.9 4.1 4.7 22.4 4.8 5.5 11.9 21.4 4.5 17.7 3.1 3.0 8.5 6.5 44.7 90.1 35.3 6.1 1.3 17.1 7.7 0.8 4.7 10.5 12.5 16.6 12.9 23.5 3.4 12.9 14.7 0.1 15.0 34.0 7.0 7.4 30.3 36.7 12.4 13.2 59.7 4.4 8.2 13.6 7.6 2.8 18.2 7.2 7.6 17.9 23.3 0.2 1.4 6.9 55.2 8.8 30.0 22.9 18.0 8.9 25.7 0.1 38.7 11.5 7.3 3.1 34.6 8.2 5.1 40.5 6.0 5.9 33.8 4.0 2.4 10.3 10.3 7.9 0.7 9.9 8.2 26.3 52.9 14.1 0.0 1.0 7.8 7.9 0.7 2.9 5.9 5.9 7.7 4.5 11.3 5.8 4.1 1.6 1.8 0.5 13.4 7.6 3.4 19.9 17.9 18.2 23.5 21.4 58.9 29.3 22.7 26.2 22.4 21.4 44.7 39.0 3.2 2.7 5.5 13.6 15.6 29.5 319.5 21.6 1.9 30.7 37.6 3.5 20.0 164.2 31.3 0.0 2.4 25.3 5.3 13.7 123.9 33.7 21.3 7.3 19.6 18.6 7.4 0.6 58.2 14.1 19.7 11.2 15.6 5.7 12.0 7.5 3.7 32.3 5.0 1.2 6.5 18.3 8.8 86.4 29.0 4.4 26.0 33.8 1.9 18.5 6.5 25.7 2.0 1.0 45.2 5.1 3.8 32.5 39.3 0.8 32.0 57.8 4.1 13.1 22.5 28.6 24.0 21.6 29.5 12.8 3.1 19.7 8.2 9.1 60.6 NMI ENSG00000123609 "N-myc and STAT interactor" Q13287 2 151270470-151289894 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 207.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008588 Approved Supported Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "HPA008588: AB_1079493" "unprognostic (5.28e-2)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-2)" "unprognostic (9.25e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.42e-2)" "unprognostic (1.08e-1)" "unprognostic (4.51e-3)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.57e-7)" "unprognostic (1.91e-1)" "unprognostic (4.69e-2)" "unprognostic (1.52e-2)" "unprognostic (4.57e-2)" 20.6 15.7 7.3 44.5 7.1 74.5 23.3 7.0 10.4 15.2 7.4 25.9 33.7 13.9 16.6 19.0 19.8 24.0 7.5 7.1 7.7 14.0 35.5 28.6 43.4 8.6 7.7 16.8 7.8 6.3 4.2 34.2 8.2 13.2 26.7 1.4 20.2 17.2 4.8 19.4 33.8 20.9 8.2 47.5 24.9 6.6 7.9 44.4 16.9 8.3 33.5 27.9 10.5 8.2 53.2 25.7 1.3 0.0 14.4 39.4 49.3 14.6 36.8 74.1 112.0 5.9 119.9 51.0 55.4 23.5 24.5 29.6 5.6 13.8 18.6 110.0 3.0 144.9 27.3 3.1 63.1 139.9 40.2 25.7 18.3 44.1 10.0 32.1 91.8 56.4 74.0 12.6 14.4 41.6 116.4 207.7 29.5 10.9 37.6 125.5 2.9 45.8 60.9 46.1 7.4 0.3 32.0 35.1 20.5 5.1 5.6 157.9 47.5 10.5 23.3 33.8 22.3 1.8 2.0 3.2 24.5 166.4 11.3 251.3 121.3 140.5 62.7 172.8 74.3 64.8 66.1 63.4 108.8 58.5 52.1 54.3 466.8 98.1 170.0 43.3 62.3 104.3 7.3 7.1 7.0 10.4 7.1 7.7 8.6 7.7 8.2 8.2 7.9 8.2 37.3 25.6 24.9 2.9 22.9 16.7 21.1 47.0 15.4 0.3 13.8 15.1 7.0 18.6 35.6 12.9 0.0 76.4 33.4 21.4 15.6 66.6 3.4 36.2 9.0 41.1 18.0 55.5 0.4 41.1 69.4 19.1 15.3 23.8 36.1 17.7 27.5 17.8 80.2 0.0 0.2 25.1 8.2 49.7 25.6 1.7 19.6 51.5 1.8 12.2 86.5 7.4 57.7 5.0 0.7 40.2 34.5 13.9 12.9 19.1 35.3 35.3 47.4 0.1 6.6 11.7 15.2 3.6 2.2 19.4 17.8 54.5 36.2 23.1 24.9 23.3 NMS ENSG00000204640 "Neuromedin S" Q5H8A3 2 100470482-100483280 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "medulla oblongata: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HL-60: 8.4;HMC-1: 4.8" "Group enriched" "Detected in some" 4 "basal ganglia: 2.4;hypothalamus: 5.4;pons and medulla: 1.3" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 2.7 0.1 0.2 1.7 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 38.5;vagina: 30.7" "Group enriched" "Detected in many" 4 "Squamous epithelial cells: 212.4;Suprabasal keratinocytes: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Cell line enhanced" "Detected in many" "Daudi: 90.2;HaCaT: 382.6;K-562: 311.3;Karpas-707: 135.7" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA025926: AB_1854539" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (5.83e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.19e-2)" "unprognostic (7.12e-2)" "unprognostic (7.29e-3)" "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.07e-10)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (2.54e-2)" "unprognostic (5.55e-2)" 0.1 0.3 0.4 0.7 0.5 9.7 1.5 0.6 1.1 12.3 0.0 1.4 0.8 0.1 0.0 100.2 0.2 0.0 0.2 0.3 2.8 0.2 0.0 0.8 0.5 1.1 2.6 0.1 0.1 0.0 2.3 0.8 0.8 0.2 0.8 0.1 14.3 0.2 0.1 38.5 1.4 0.2 3.0 0.1 4.0 2.2 6.8 1.7 2.5 0.0 7.7 0.1 30.7 0.4 41.3 0.3 22.1 5.6 0.0 0.0 0.0 0.0 0.0 2.9 7.8 0.3 61.5 90.2 8.6 0.0 8.5 382.6 46.1 3.3 2.3 5.6 25.1 0.6 36.0 0.0 0.0 0.0 0.3 0.0 4.2 0.0 3.0 10.0 0.4 6.4 311.3 135.7 0.3 9.9 1.2 0.2 11.7 7.5 11.4 0.2 0.0 0.5 1.9 0.4 19.5 49.0 30.9 0.8 0.1 4.2 20.9 0.1 2.7 0.2 27.5 0.3 54.5 39.1 0.3 0.0 18.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.6 1.1 0.3 2.8 1.1 2.6 0.8 3.0 6.8 0.4 0.0 0.0 2.3 0.0 0.6 16.3 0.6 16.2 4.0 0.2 0.9 1.3 0.1 0.0 8.0 0.0 0.0 2.0 0.0 0.6 0.0 0.1 0.4 3.9 0.3 0.7 0.0 14.5 0.2 0.2 0.1 4.4 29.6 5.8 1.3 0.9 0.0 0.1 0.3 0.0 17.2 0.8 20.3 0.0 1.6 0.3 0.0 0.2 3.6 0.0 0.1 2.0 0.0 1.0 0.2 2.4 0.2 0.0 1.2 0.4 0.0 0.0 7.0 0.0 0.0 0.0 1.2 5.8 10.0 212.4 73.6 0.1 0.7 0.2 2.6 12.0 NODAL ENSG00000156574 "Nodal growth differentiation factor" Q96S42 10 70431936-70447951 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;skeletal muscle: 2.3" "Group enriched" "Detected in some" 26 "Early spermatids: 15.4;Late spermatids: 38.5" "Cancer enriched" "Detected in some" 10 "testis cancer: 20.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.9;SH-SY5Y: 1.4;SuSa: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA045201 Uncertain "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "HPA045201: AB_2679252" "unprognostic (3.07e-2)" "unprognostic (2.10e-1)" "unprognostic (1.51e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-1)" "unprognostic (4.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.65e-1)" "unprognostic (5.66e-3)" "unprognostic (3.12e-2)" "unprognostic (8.77e-2)" "unprognostic (1.61e-1)" "unprognostic (1.63e-5)" "unprognostic (4.37e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (2.02e-1)" 0.7 0.0 0.7 0.0 0.6 0.6 0.5 2.3 0.6 0.6 0.0 0.4 0.2 0.3 0.0 0.3 0.3 0.2 0.3 0.5 0.6 0.1 0.1 0.4 0.2 0.7 0.6 0.3 0.1 0.0 0.1 0.2 0.7 0.2 0.0 1.3 0.2 0.0 2.3 1.0 0.2 0.0 0.5 0.2 0.2 1.9 0.6 0.2 0.1 0.0 0.0 0.4 0.4 0.6 0.3 0.2 0.8 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.9 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.1 0.2 0.5 0.2 0.0 0.2 0.2 0.5 0.0 0.1 0.1 1.4 0.4 0.1 0.0 3.5 0.4 0.1 0.0 0.0 0.2 0.1 0.1 0.5 1.1 1.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.6 2.3 0.6 0.5 0.6 0.7 0.6 0.7 0.5 0.6 0.6 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 38.5 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NOG "SYM1, SYNS1" ENSG00000183691 Noggin Q13253 17 56593699-56595611 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2;placenta: 10.6" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 72.8;naive CD8 T-cell: 34.9" "Lineage enriched" "Detected in single" 78 "T-cells: 72.8" "Cell line enhanced" "Detected in many" "EFO-21: 123.3;LHCN-M2: 38.1;NB-4: 28.8;PC-3: 37.9;U-2 OS: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061318 Approved "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 32: Non-specific - Translation" "HPA061318: AB_2684478" "unprognostic (1.49e-1)" "unprognostic (1.17e-2)" "unprognostic (1.49e-5)" "prognostic favorable (6.66e-4)" "unprognostic (4.69e-2)" "unprognostic (5.23e-3)" "unprognostic (1.26e-2)" "unprognostic (3.06e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (6.86e-5)" "unprognostic (2.88e-1)" "unprognostic (1.14e-6)" "unprognostic (8.39e-2)" "unprognostic (1.40e-1)" "unprognostic (5.00e-1)" "unprognostic (1.65e-1)" 0.7 0.1 6.1 0.6 4.8 0.2 0.3 1.7 4.2 4.7 0.3 0.3 0.1 0.3 0.1 0.2 0.5 0.0 0.5 4.0 3.6 0.4 0.1 0.7 1.8 2.1 5.0 0.0 0.1 0.0 0.7 10.6 1.8 0.8 0.0 0.0 0.3 1.4 3.5 0.3 0.5 0.1 2.4 0.7 0.9 0.7 8.2 0.6 0.4 0.8 0.4 0.8 2.7 2.0 6.3 0.2 0.2 0.0 0.2 0.0 0.0 3.2 3.5 1.2 1.3 0.4 1.2 0.0 123.3 1.5 4.8 0.5 2.2 0.3 3.4 0.1 2.2 0.0 5.2 0.0 0.0 0.9 0.0 0.5 0.7 0.0 0.5 0.4 0.1 0.1 0.0 0.0 38.1 0.2 1.1 28.8 2.6 0.0 37.9 17.0 11.6 0.0 2.9 0.0 0.2 0.0 6.5 0.1 0.0 9.9 0.1 0.5 0.7 2.3 38.5 0.2 2.7 0.0 0.1 0.4 0.0 3.2 0.0 0.9 0.1 0.2 0.6 0.2 0.2 0.1 4.3 0.5 0.1 0.1 72.8 34.9 0.8 0.4 0.3 0.3 3.4 3.1 6.1 4.8 1.7 4.2 4.0 3.6 2.1 5.0 1.8 2.4 8.2 2.0 0.4 0.0 0.0 2.0 0.3 0.0 0.4 0.0 0.6 0.0 0.1 0.9 1.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.5 0.1 0.6 1.5 0.3 0.0 2.5 0.2 0.0 12.2 1.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 1.0 1.5 0.1 0.6 0.0 0.0 0.3 0.3 0.0 0.4 0.0 0.0 0.0 2.3 0.4 0.0 1.7 0.4 0.1 0.8 2.0 0.0 0.0 0.1 NOTCH2NLA "N2N, NOTCH2NL" ENSG00000264343 "Notch 2 N-terminal like A" Q7Z3S9 1 146146203-146229026 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 1.6;dendritic cells: 2.8;Extravillous trophoblasts: 2.0;Fibroblasts: 1.2;Hofbauer cells: 2.1;Macrophages: 2.2;Plasma cells: 3.0;Smooth muscle cells: 1.4;Syncytiotrophoblasts: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB004669 Uncertain "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 29: U-266 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "CAB004669: AB_426149" "unprognostic (1.54e-1)" "unprognostic (8.28e-3)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (2.75e-1)" "unprognostic (2.09e-1)" "unprognostic (1.35e-2)" "unprognostic (3.40e-2)" "unprognostic (1.56e-1)" "unprognostic (4.28e-4)" "unprognostic (1.26e-2)" "unprognostic (1.81e-1)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.91e-1)" "unprognostic (7.59e-2)" "unprognostic (1.83e-2)" 14.5 5.9 6.3 6.8 4.2 5.3 13.4 2.1 9.7 18.9 17.1 7.8 5.1 9.0 13.6 22.0 9.8 6.9 10.6 8.9 6.1 8.6 15.5 13.1 5.9 6.9 4.9 11.6 10.9 8.8 3.7 9.6 4.9 14.5 6.4 8.6 14.9 7.8 9.1 29.0 7.1 8.5 2.4 11.4 7.4 34.0 7.7 5.4 10.6 3.8 6.8 9.1 21.0 6.5 22.8 7.8 12.2 4.4 11.4 31.4 4.8 12.3 20.7 14.1 16.0 4.3 10.5 5.0 5.1 9.7 7.6 10.1 6.9 15.7 22.1 13.5 5.8 17.1 15.8 2.0 12.9 7.6 6.1 28.5 4.9 15.5 33.2 17.4 10.2 7.4 5.4 26.6 20.1 15.9 4.2 5.2 3.6 1.7 14.9 4.1 11.9 16.2 7.4 12.0 1.9 1.2 21.0 12.2 4.9 7.9 20.5 7.7 42.2 9.5 8.2 19.9 16.1 51.0 14.2 12.5 15.6 6.1 8.4 16.8 13.4 27.9 4.3 13.4 4.1 14.3 4.0 4.0 10.5 11.4 5.8 4.2 19.5 4.5 18.1 17.3 4.2 3.0 6.3 4.2 2.1 9.7 8.9 6.1 6.9 4.9 4.9 2.4 7.7 6.5 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 NOTCH2NLB ENSG00000286019 "Notch 2 N-terminal like B" P0DPK3 1 148607040-148679779 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Notch signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 26.2;U-266/70: 89.3;U-266/84: 29.2" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: U-266 - Adaptive immune response" 2.4 1.1 3.4 1.1 3.0 4.7 3.7 2.4 4.5 11.4 4.6 1.8 0.9 1.6 2.9 3.0 2.0 3.0 1.2 3.5 2.6 1.9 3.5 2.0 2.1 3.5 2.9 2.0 3.3 2.3 2.0 2.7 3.6 1.6 1.2 2.0 2.4 2.2 3.1 1.7 2.4 2.8 3.3 1.0 5.5 3.7 0.9 2.1 0.0 2.3 2.6 3.4 8.6 3.4 2.1 2.1 2.7 2.3 1.3 6.1 6.1 4.3 4.2 1.9 6.1 0.7 1.4 1.4 3.7 2.8 2.0 7.1 2.7 3.5 3.2 6.9 7.2 0.8 2.6 4.2 1.9 9.4 3.3 3.4 15.6 6.6 4.8 2.9 1.3 26.2 8.9 6.7 1.2 2.7 1.0 2.6 7.2 2.6 3.7 9.9 7.7 1.8 0.1 0.1 11.9 6.1 0.7 0.8 7.8 2.4 12.8 1.6 3.5 7.4 4.7 89.3 29.2 3.4 5.7 2.9 5.9 11.5 14.1 29.3 2.3 12.6 2.1 18.0 2.6 2.3 14.4 15.5 3.3 3.0 15.8 4.1 13.5 15.2 3.1 3.8 3.4 3.0 2.4 4.5 3.5 2.6 3.5 2.9 2.7 2.8 3.7 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NOTCH2NLC ENSG00000286219 "Notch 2 N-terminal like C" P0DPK4 1 149390614-149468030 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Notch signaling pathway" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 74.2;U-266/70: 121.3" "Secreted to blood" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 29: U-266 - Adaptive immune response" 7.3 2.0 9.6 5.5 8.2 18.0 12.1 6.4 16.4 13.2 14.5 5.4 3.5 6.4 9.8 9.8 7.7 6.4 6.9 10.4 9.3 3.9 21.6 6.1 8.3 10.0 9.0 7.1 5.7 7.6 5.6 8.1 9.5 6.1 14.3 6.8 8.1 2.5 12.7 2.6 5.2 7.3 7.3 3.1 20.8 10.6 7.4 6.1 3.9 8.3 8.4 8.8 14.2 6.0 4.0 5.0 9.0 11.1 2.5 4.5 39.9 17.9 23.8 3.6 12.2 2.2 3.6 17.1 9.6 5.0 5.1 19.7 10.8 7.1 3.4 11.7 43.8 1.8 37.9 6.1 3.7 33.5 8.1 28.3 74.2 10.7 14.4 8.3 3.1 50.7 17.0 29.8 5.1 7.7 1.6 8.6 13.6 4.8 7.9 27.3 17.9 16.4 0.5 0.4 12.9 12.3 2.0 5.0 10.6 9.5 12.8 5.4 8.8 9.5 9.8 121.3 35.9 7.6 11.9 6.4 8.0 17.8 29.3 47.3 3.6 21.4 5.0 57.7 5.9 5.8 44.3 26.6 5.9 4.0 14.1 8.3 18.9 23.6 8.2 11.3 9.6 8.2 6.4 16.4 10.4 9.3 10.0 9.0 8.1 7.3 10.6 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 135.7" "Cell type enriched" "Detected in some" 45 "Extravillous trophoblasts: 1002.5" "Cancer enhanced" "Detected in many" "stomach cancer: 48.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 428.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" NA NA 1900000 "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" 0.0 0.1 1.6 0.0 1.9 0.0 0.2 0.6 1.8 0.2 0.1 0.0 1.1 2.1 0.3 0.3 0.4 0.2 0.3 1.0 1.0 1.2 10.0 2.2 0.0 1.7 2.7 0.1 0.4 0.9 0.2 135.7 1.3 0.3 0.0 0.0 0.6 0.1 8.2 2.2 0.3 0.1 0.9 0.2 2.1 2.8 1.3 0.0 0.0 0.5 0.0 1.4 0.2 0.8 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 10.0 0.4 0.0 1.8 0.3 0.2 0.4 2.4 0.0 0.0 0.1 1.1 2.2 2.8 428.6 0.2 0.4 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.2 11.2 0.0 0.0 0.6 0.0 0.2 0.1 67.9 0.4 0.0 0.2 0.1 0.0 0.2 15.7 1.6 4.2 1.7 6.2 2.3 0.1 4.9 0.0 0.5 6.3 0.0 0.2 0.1 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 0.6 1.8 1.0 1.0 1.7 2.7 1.3 0.9 1.3 0.8 0.0 0.0 3.7 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.6 1.3 1.2 0.0 0.0 0.0 0.0 10.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.8 0.0 0.0 0.6 0.0 1002.5 1.2 1.5 0.3 0.0 0.1 0.0 3.6 18.4 0.0 1.1 0.1 0.0 0.0 0.3 0.2 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.5 12.7 0.0 0.0 22.0 0.1 0.0 0.3 0.0 NPB "PPL7, PPNPB" ENSG00000183979 "Neuropeptide B" Q8NG41 17 81900745-81902905 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 8.1" "Group enriched" "Detected in many" 6 "Spermatogonia: 41.5;Syncytiotrophoblasts: 97.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.2;PC-3: 3.4;RH-30: 1.8;SH-SY5Y: 2.7;U-2 OS: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (2.44e-2)" "unprognostic (6.21e-2)" "unprognostic (2.90e-1)" "unprognostic (3.47e-3)" "unprognostic (9.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.31e-1)" "unprognostic (1.92e-1)" "unprognostic (3.55e-2)" "unprognostic (5.40e-2)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-2)" "unprognostic (3.71e-1)" "unprognostic (4.32e-1)" 0.3 0.1 2.2 0.0 1.8 0.0 0.2 2.6 2.4 0.4 0.0 0.2 0.0 0.3 0.0 0.3 0.3 0.0 0.4 1.5 7.1 0.3 0.8 0.1 0.1 5.2 5.0 0.5 0.1 0.2 0.3 0.2 4.3 0.2 0.0 0.2 0.2 0.1 0.2 0.4 0.5 0.1 3.8 0.4 0.6 1.5 6.2 0.2 0.1 0.0 0.1 0.2 0.3 8.1 0.2 0.8 0.6 0.1 0.1 0.1 0.5 0.3 0.1 0.2 0.0 0.4 0.0 0.2 0.1 0.1 0.4 0.0 0.3 0.1 0.2 2.2 0.0 0.4 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.2 0.1 0.4 0.0 0.4 0.6 0.0 0.1 0.1 0.0 0.4 0.2 0.1 3.4 0.1 1.8 0.0 0.0 0.2 0.4 2.7 0.2 0.0 0.3 1.0 0.0 0.0 0.2 0.2 2.3 0.0 0.2 0.1 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.8 2.6 2.4 1.5 7.1 5.2 5.0 4.3 3.8 6.2 8.1 1.1 0.0 0.0 1.3 0.4 2.5 0.6 1.8 1.2 1.0 3.3 6.6 0.0 1.5 0.6 0.0 0.0 2.1 0.1 1.2 1.9 0.9 1.5 0.8 3.0 0.9 0.0 0.0 0.4 0.2 3.6 3.3 4.6 0.3 0.0 2.6 1.1 0.2 1.2 0.0 1.2 0.4 0.0 2.6 1.6 3.8 5.0 0.2 5.4 0.0 0.1 0.4 0.0 1.0 4.5 1.8 3.7 2.6 0.2 0.9 0.9 2.1 0.7 1.2 0.0 1.0 3.4 10.7 41.5 1.3 1.1 97.0 0.4 0.5 0.6 0.4 NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "epididymis: 16783.1" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2034.2;Hofbauer cells: 2898.5;Kupffer cells: 2035.4" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 769.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 668.7;classical monocyte: 1300.7;intermediate monocyte: 1772.7;myeloid DC: 587.8;neutrophil: 674.2;non-classical monocyte: 1252.1;plasmacytoid DC: 2113.2" "Group enriched" "Detected in all" 5 "dendritic cells: 2113.2;granulocytes: 674.2;monocytes: 1772.7" "Cell line enhanced" "Detected in all" "ASC diff: 1619.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" NA NA 53000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032888: AB_2157036, HPA000835: AB_1079499" "unprognostic (1.27e-3)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (6.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.97e-1)" "prognostic favorable (6.55e-4)" "unprognostic (1.42e-1)" 260.1 297.0 127.1 261.3 145.4 305.3 221.3 152.2 190.6 284.5 434.0 259.7 201.7 196.7 16783.1 185.0 170.0 356.0 215.1 118.1 156.9 322.4 202.4 786.0 360.3 185.7 145.6 283.1 219.9 241.3 197.5 263.1 179.2 164.2 220.8 48.6 221.9 261.3 58.7 181.6 193.3 180.5 151.1 305.6 206.8 156.8 172.1 134.4 444.7 114.7 241.9 347.4 187.9 195.5 297.2 199.3 124.8 179.4 1619.3 498.6 404.8 194.1 707.1 200.9 398.9 351.7 420.3 78.6 141.6 181.9 372.6 595.9 170.0 405.5 188.6 120.4 126.3 29.6 96.7 296.2 348.6 51.0 548.4 467.7 388.9 173.7 336.9 930.2 298.1 87.0 32.9 601.4 224.0 106.9 70.1 75.9 52.9 489.0 307.9 39.5 219.1 281.6 511.1 735.0 5.5 91.3 296.3 120.3 298.0 359.6 205.2 225.7 268.9 291.9 342.0 396.1 188.2 253.7 452.5 24.2 292.1 168.4 163.4 668.7 1300.7 274.1 92.2 1772.7 87.9 295.2 126.5 92.3 587.8 241.8 120.9 100.5 674.2 99.5 1252.1 2113.2 187.8 1304.5 127.1 145.4 152.2 190.6 118.1 156.9 185.7 145.6 179.2 151.1 172.1 195.5 154.9 381.4 2034.2 11.1 160.2 374.9 557.8 1074.2 170.2 9.9 138.6 220.5 55.4 163.0 626.9 331.1 22.9 228.3 664.0 301.0 305.2 500.4 90.9 123.8 168.5 276.5 119.7 65.4 2.1 279.4 803.3 318.1 61.7 161.0 341.4 104.2 447.3 195.6 2898.5 8.4 3.8 264.8 832.1 2035.4 750.9 69.6 566.7 1462.6 602.9 6.5 790.5 167.4 117.4 7.5 24.4 368.3 405.1 291.9 287.4 357.9 298.1 969.0 393.3 25.1 131.5 118.3 155.9 268.1 166.7 182.6 320.7 210.4 109.9 330.0 298.5 521.6 NPFF FMRFAL ENSG00000139574 "Neuropeptide FF-amide peptide precursor" O15130 12 53506690-53507638 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "epididymis: 820.5" "Cell type enhanced" "Detected in some" "Astrocytes: 11.1;Excitatory neurons: 1.3;Inhibitory neurons: 1.2;Microglial cells: 1.9;Oligodendrocytes: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HHSteC: 13.3" "Region enriched" "Detected in some" 7 "pons and medulla: 11.4" "Region enriched" "Detected in all" 7 "cerebellum: 50.8" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" 0.2 0.4 1.4 0.0 1.4 0.0 0.1 1.4 9.7 0.2 1.4 0.1 0.8 0.0 820.5 0.1 0.1 0.1 0.2 1.4 2.1 0.1 0.1 0.3 0.0 3.4 3.2 0.2 0.1 0.0 0.1 0.0 1.6 0.1 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.0 3.1 0.1 0.1 0.1 1.8 0.1 0.1 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.5 0.2 0.6 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.1 1.6 0.3 0.0 0.6 0.2 0.0 0.2 0.2 0.4 1.5 0.0 0.0 0.2 0.0 0.5 0.1 1.7 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.4 9.7 1.4 2.1 3.4 3.2 1.6 3.1 1.8 1.6 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 NPIPB7 "LOC440350, NPIPL1" ENSG00000233232 "Nuclear pore complex interacting protein family member B7" O75200 16 28456372-28471175 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 22.2" "Cell type enriched" "Detected in some" 4 "Early spermatids: 152.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA011188, HPA053611" Approved Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (1.94e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-3)" "unprognostic (3.35e-2)" "unprognostic (3.44e-1)" "unprognostic (2.78e-2)" "unprognostic (3.62e-2)" "unprognostic (3.04e-2)" "unprognostic (4.40e-1)" "unprognostic (2.22e-1)" "unprognostic (7.73e-2)" "unprognostic (2.03e-2)" 1.4 0.9 4.0 1.4 4.0 2.6 1.0 6.1 8.2 0.5 0.1 1.4 1.0 1.3 2.1 0.2 0.7 0.3 0.4 4.0 3.0 0.6 1.2 0.8 1.5 3.1 0.7 1.6 1.7 0.4 0.3 0.7 1.9 1.0 1.4 4.5 0.8 1.1 5.0 3.2 1.3 0.7 0.0 1.3 2.4 22.2 2.7 1.0 0.6 1.0 0.6 0.5 0.1 1.7 0.6 4.1 3.0 2.0 1.3 1.3 6.3 1.5 0.1 0.3 0.5 1.5 1.8 3.2 0.9 1.0 0.3 2.0 0.9 0.6 0.2 1.1 1.5 1.2 4.5 3.1 0.6 2.8 6.3 1.4 3.1 1.0 0.9 1.6 0.1 1.9 1.0 2.2 0.7 5.4 0.7 2.9 1.9 0.2 0.2 2.6 1.8 1.6 0.2 1.5 1.6 0.8 1.3 0.5 0.6 2.8 2.2 1.2 2.2 1.1 2.8 1.5 1.0 4.4 2.2 3.1 0.4 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 4.0 6.1 8.2 4.0 3.0 3.1 0.7 1.9 0.0 2.7 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 1.8 0.0 0.2 0.0 0.1 0.0 0.0 152.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.8 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.9;Alveolar cells type 2: 103.7;Club cells: 56.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 30.9;CAPAN-2: 19.1;HeLa: 32.3;Hep G2: 27.1;MCF7: 24.3;RPTEC TERT1: 37.7;T-47d: 51.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" 22.8 6.3 9.7 5.6 7.9 0.2 27.0 4.7 8.0 32.4 5.7 24.5 56.1 20.9 22.2 10.9 22.4 30.5 5.2 7.5 14.6 105.0 4.0 137.0 4.5 6.1 31.8 10.9 40.1 1.0 47.4 3.4 9.2 82.9 25.2 2.4 8.9 18.7 4.9 8.2 74.1 14.1 4.4 14.8 14.9 3.1 10.5 14.2 234.5 11.5 5.4 9.7 22.1 6.6 0.0 0.2 0.3 0.6 0.0 0.0 30.9 0.2 0.1 0.0 0.0 14.9 19.1 0.2 0.8 0.2 0.0 1.7 7.4 0.0 0.0 0.0 8.4 0.8 32.3 27.1 0.1 0.0 0.2 3.2 2.4 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.0 24.3 0.4 1.5 0.3 0.1 12.0 0.0 0.1 0.3 37.7 1.6 1.7 0.6 1.8 14.1 0.0 4.1 51.2 1.3 0.0 0.6 0.4 0.5 1.1 0.3 1.1 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 7.9 4.7 8.0 7.5 14.6 6.1 31.8 9.2 4.4 10.5 6.6 5.2 185.9 103.7 15.3 0.0 1.9 5.2 13.1 1.8 1.1 22.2 7.0 2.5 27.1 56.4 33.1 0.0 2.4 0.7 5.9 1.9 24.7 11.0 1.0 1.5 18.4 15.6 0.0 1.0 2.5 0.2 8.3 1.1 1.9 0.0 3.3 2.9 0.3 0.3 0.0 10.0 10.6 4.1 0.0 1.5 15.4 2.5 0.6 5.4 14.0 0.0 0.0 0.0 2.0 0.3 7.5 3.4 0.0 0.0 28.4 19.6 4.3 6.4 0.2 0.0 1.9 26.4 2.4 2.0 3.6 1.1 1.5 0.3 1.5 11.0 5.7 NPPA "ANP, PND" ENSG00000175206 "Natriuretic peptide A" P01160 1 11845709-11848345 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 873 "heart muscle: 60060.6" "Cell type enriched" "Detected in some" 23 "Cardiomyocytes: 62235.0" "Cancer enriched" "Detected in some" 9 "glioma: 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 9.6;SH-SY5Y: 9.5" "Region enriched" "Detected in some" 7 "olfactory bulb: 22.8" "Low region specificity" "Detected in all" "HPA058269, HPA064007" Enhanced "Secreted to blood" NA NA 1200000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA058269: AB_2683660, HPA064007: " "unprognostic (1.27e-3)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.48e-1)" "unprognostic (3.25e-2)" "unprognostic (9.72e-3)" "unprognostic (2.21e-1)" "unprognostic (5.93e-4)" "unprognostic (2.31e-1)" "unprognostic (1.59e-1)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" 8.3 3.0 1.7 0.7 2.1 0.6 18.0 1.8 2.4 1.2 2.3 5.0 0.2 3.3 12.9 2.8 1.3 0.9 60060.6 2.2 1.5 2.6 5.0 58.1 1.2 1.7 1.5 12.1 68.7 0.9 3.9 5.9 1.4 5.1 0.0 0.4 28.5 0.0 8.9 5.8 6.1 0.7 1.3 3.1 3.6 3.9 1.7 0.5 7.1 0.0 0.0 1.2 3.9 2.0 0.5 0.2 0.3 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.9 0.6 0.8 0.0 0.0 0.4 1.0 0.0 0.0 0.0 0.2 0.4 1.0 0.3 1.8 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 1.2 0.0 0.3 0.3 1.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.6 9.6 9.5 0.0 0.0 0.5 0.3 0.3 0.1 0.0 0.4 0.7 0.6 0.1 0.4 0.8 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 2.1 1.8 2.4 2.2 1.5 1.7 1.5 1.4 1.3 1.7 2.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62235.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 339.1 0.0 0.0 0.3 0.0 0.0 2684.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 636.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPPB ENSG00000120937 "Natriuretic peptide B" P16860 1 11857464-11858945 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 767 "heart muscle: 5154.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 351.7;Ductal cells: 266.6;Pancreatic endocrine cells: 86.2" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Group enriched" "Detected in some" 4 "basal ganglia: 3.4;cerebral cortex: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 135.5;CACO-2: 362.2;SuSa: 67.7" "Region enhanced" "Detected in single" "pons and medulla: 1.4" HPA077324 Approved Vesicles,Cytosol "Secreted to blood" NA NA 9680 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Vesicles Cytosol "HPA077324: " "unprognostic (3.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (4.23e-1)" "unprognostic (3.28e-2)" 1.0 0.3 0.3 0.1 3.4 0.0 0.7 0.4 1.8 0.3 0.1 0.3 0.0 0.3 0.3 0.2 0.0 0.6 5154.6 0.3 0.3 0.3 0.5 6.7 0.9 0.3 0.4 0.8 4.0 0.1 0.5 0.8 0.3 0.5 0.0 0.1 1.2 0.0 0.8 0.5 0.4 0.0 0.6 0.1 0.7 0.8 0.5 0.1 0.5 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 135.5 0.3 0.0 2.1 1.1 362.2 0.0 0.0 0.1 0.1 0.3 3.8 0.1 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.0 67.7 0.0 0.0 0.0 0.0 32.0 0.2 0.2 0.0 0.1 0.0 0.1 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 0.4 1.8 0.3 0.3 0.3 0.4 0.3 0.6 0.5 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 351.7 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 266.6 0.1 0.8 0.1 4.9 0.0 0.0 0.2 8.3 2.2 11.7 0.0 1.4 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.2 0.0 0.0 0.0 86.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 17.6 5.8 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.1 NPPC CNP ENSG00000163273 "Natriuretic peptide C" P23582 2 231921809-231926396 "Predicted secreted proteins, Transporters" Osteogenesis "Hormone, Vasoactive" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 33.5" "Group enriched" "Detected in many" 8 "Basal squamous epithelial cells: 190.1;Skeletal myocytes: 264.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "medulla oblongata: 33.5;spinal cord: 30.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;NTERA-2: 3.9;SCLC-21H: 5.5;SK-MEL-30: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.5;spinal cord: 12.5" HPA035362 Uncertain "Secreted to blood" NA NA 6140 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA035362: AB_10671103" "unprognostic (9.70e-2)" "unprognostic (4.45e-2)" "unprognostic (1.99e-1)" "unprognostic (1.06e-2)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-3)" "unprognostic (9.81e-3)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" "unprognostic (4.06e-2)" "unprognostic (1.17e-1)" "unprognostic (6.58e-2)" "unprognostic (1.18e-1)" "unprognostic (3.72e-1)" "unprognostic (1.91e-1)" 0.3 0.1 0.8 2.1 0.9 1.3 0.7 2.8 3.4 1.3 0.0 4.1 0.1 0.6 0.0 3.2 2.6 0.0 5.3 2.0 3.9 0.2 0.0 0.0 1.4 33.5 4.4 1.3 0.1 0.0 2.7 0.2 4.8 4.3 0.2 2.4 1.1 0.4 0.7 0.6 0.9 0.5 30.9 0.4 2.4 0.2 4.6 2.9 0.5 0.1 2.0 0.2 0.4 6.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 1.0 0.0 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.5 0.3 0.2 0.2 26.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 2.8 3.4 2.0 3.9 33.5 4.4 4.8 30.9 4.6 6.5 2.1 0.0 0.0 0.7 1.3 3.4 27.1 5.9 190.1 1.1 6.5 18.3 1.9 0.0 0.1 11.0 10.4 0.2 0.6 4.2 0.0 1.1 0.3 3.6 1.3 1.6 3.5 0.0 0.0 0.0 0.0 10.9 5.6 4.8 0.0 0.3 0.0 0.0 0.1 0.0 1.5 3.2 0.0 0.0 1.7 0.0 0.3 1.6 1.8 0.0 2.5 15.2 0.0 0.0 1.3 0.8 3.1 0.0 5.8 11.5 0.0 0.0 0.0 4.1 0.0 264.2 2.0 1.2 7.0 13.2 1.1 0.3 1.7 0.0 2.9 3.1 NPS ENSG00000214285 "Neuropeptide S" P0C0P6 10 127549309-127553540 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "head and neck cancer: 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "midbrain: 5.4;pons and medulla: 5.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 4.8;white matter: 2.2" CAB020139 Uncertain "Secreted in brain" NA NA "CAB020139: AB_776718" "unprognostic (2.83e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPTX1 ENSG00000171246 "Neuronal pentraxin 1" Q15818 17 80466834-80477843 "Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 107.8;intestine: 31.6" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 175.2;Excitatory neurons: 88.6;Late spermatids: 44.8" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 32.0;HeLa: 26.0;SiHa: 40.7;U-138 MG: 85.2;WM-115: 120.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 55.3;cerebellum: 128.1;cerebral cortex: 102.2;hippocampal formation: 131.3" HPA077062 Enhanced Approved "Secreted in brain" NA NA 1100000 "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA077062: AB_2732329" "unprognostic (2.37e-2)" "unprognostic (1.18e-1)" "unprognostic (1.81e-2)" "unprognostic (6.95e-2)" "unprognostic (4.16e-3)" "unprognostic (2.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.63e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-1)" "unprognostic (1.81e-2)" "unprognostic (9.63e-3)" "unprognostic (1.05e-6)" "unprognostic (1.41e-4)" "unprognostic (1.35e-1)" "unprognostic (8.86e-6)" "unprognostic (2.71e-3)" 0.4 5.1 95.2 1.0 88.8 0.1 0.4 77.7 94.5 0.2 0.0 31.6 0.7 0.8 2.2 0.8 0.8 1.2 0.0 107.8 0.7 0.2 0.0 1.3 0.9 20.1 1.0 0.6 0.2 0.0 2.4 1.2 1.7 0.7 2.1 13.0 0.0 2.5 2.7 3.2 4.2 0.8 3.5 2.1 3.9 1.2 1.3 11.9 0.1 0.6 0.1 0.6 0.1 81.3 0.0 2.0 0.5 0.2 0.4 0.5 0.0 2.0 0.0 0.1 0.0 0.7 0.2 0.0 0.3 0.2 3.5 0.1 32.0 0.0 0.0 0.0 20.2 0.0 26.0 0.1 0.1 0.0 1.4 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.0 6.5 0.0 0.0 8.3 0.0 0.0 21.4 0.0 40.7 0.1 0.0 0.3 0.1 0.6 0.3 85.2 0.0 4.2 0.2 0.0 0.0 0.0 0.2 0.0 120.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 95.2 88.8 77.7 94.5 107.8 0.7 20.1 1.0 1.7 3.5 1.3 81.3 1.3 0.0 0.0 8.1 0.3 1.5 0.1 0.0 0.0 12.8 0.7 2.2 3.0 0.0 0.6 0.0 175.2 0.1 0.6 0.3 0.0 0.0 8.2 0.3 0.4 1.2 0.0 0.0 88.6 0.0 0.2 0.9 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 11.0 0.7 0.0 0.0 0.0 44.8 0.9 0.6 0.0 6.5 0.0 0.8 0.0 5.0 5.8 0.6 0.0 2.2 0.1 0.5 0.0 0.0 0.0 4.1 0.0 1.6 1.1 1.6 0.4 0.1 3.0 0.1 0.1 0.5 0.1 0.0 NPTX2 ENSG00000106236 "Neuronal pentraxin 2" P47972 7 98617285-98629869 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 135.8;pituitary gland: 210.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 93.5;Peritubular cells: 326.1;Sertoli cells: 151.2;Spermatocytes: 85.2;Spermatogonia: 94.8" "Cancer enhanced" "Detected in all" "renal cancer: 41.7" "Region enhanced" "Detected in all" "cerebral cortex: 135.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "LHCN-M2: 717.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020801, HPA049799, HPA058320" Enhanced Approved "Golgi apparatus,Actin filaments,Centrosome" "Secreted to blood" NA NA 2490000 360000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Actin filaments" Centrosome "CAB020801: , HPA049799: AB_2680889, HPA058320: AB_2732621" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (1.91e-3)" "unprognostic (9.20e-2)" "unprognostic (2.42e-2)" "unprognostic (6.04e-3)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (7.64e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (5.46e-9)" "unprognostic (1.06e-2)" "unprognostic (1.21e-1)" "unprognostic (5.33e-2)" "unprognostic (3.69e-2)" 7.0 39.2 11.2 1.9 13.6 0.5 3.8 10.1 135.8 9.9 2.5 15.3 0.5 5.7 3.5 3.0 2.8 1.1 9.8 39.2 47.3 1.1 2.6 0.9 0.1 13.8 14.5 3.7 21.4 0.6 210.8 0.1 16.2 7.2 0.8 4.7 3.7 1.6 8.9 8.2 5.4 2.5 6.4 13.0 6.7 34.3 45.6 0.5 3.1 6.7 0.3 5.5 6.9 16.8 0.0 0.0 6.5 0.2 0.0 0.5 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 21.1 2.8 1.5 0.0 0.9 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 717.9 0.0 5.7 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 33.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.2 13.6 10.1 135.8 39.2 47.3 13.8 14.5 16.2 6.4 45.6 16.8 8.6 0.0 0.6 2.9 0.3 3.8 0.5 0.0 0.0 19.9 0.2 1.4 3.4 5.7 1.3 0.0 4.2 0.0 1.0 4.5 0.0 5.4 12.0 8.5 1.8 16.9 16.0 0.0 22.1 12.8 0.2 11.1 1.5 10.5 0.0 93.5 3.9 0.7 0.5 0.0 5.3 1.2 0.0 0.0 5.4 24.2 14.0 1.3 12.4 5.6 0.0 1.6 0.0 1.0 1.8 2.9 1.1 326.1 1.0 5.2 0.5 0.1 0.0 2.8 151.2 57.2 27.1 85.2 94.8 0.1 3.0 0.1 0.8 12.7 2.3 1.2 NPVF "C7orf9, RFRP" ENSG00000105954 "Neuropeptide VF precursor" Q9HCQ7 7 25224570-25228486 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 62 "retina: 220.5" "Cell type enriched" "Detected in some" 40 "Muller glia cells: 526.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "hypothalamus: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 18 "hypothalamus: 6.1" "Region enriched" "Detected in single" 8 "hypothalamus: 3.0" HPA041733 Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 5: Muller glia cells - Visual perception" "HPA041733: AB_10794524" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 220.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 526.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPW PPL8 ENSG00000183971 "Neuropeptide W" Q8N729 16 2009926-2020755 "Predicted intracellular proteins, Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 10.6" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 188.1;Enteroendocrine cells: 158.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 6 "NB-4: 43.5;PC-3: 35.6;RPMI-8226: 74.7;SCLC-21H: 118.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.2" HPA064874 Approved "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "HPA064874: AB_2685378" "unprognostic (7.54e-2)" "unprognostic (4.45e-3)" "unprognostic (3.20e-1)" "unprognostic (4.31e-3)" "unprognostic (8.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.20e-2)" "unprognostic (6.26e-3)" "unprognostic (2.37e-1)" "unprognostic (1.81e-5)" "unprognostic (6.53e-3)" "unprognostic (1.26e-1)" "unprognostic (4.41e-1)" "unprognostic (3.43e-2)" 0.4 0.1 1.0 0.4 0.7 1.2 0.1 0.6 3.6 1.1 1.1 0.5 0.6 1.1 1.3 0.4 0.6 0.0 0.1 0.7 1.9 0.4 10.6 0.1 0.2 0.7 0.9 0.4 0.4 0.0 2.7 0.1 0.7 0.3 0.1 0.0 0.1 0.2 0.0 1.7 0.2 0.2 0.5 0.7 2.4 1.2 2.5 0.0 0.2 0.0 0.4 0.2 0.6 1.0 0.4 1.7 0.2 2.5 0.4 0.0 0.7 0.9 0.2 0.5 1.0 3.8 1.5 0.4 0.1 0.8 0.6 0.8 1.1 0.3 0.5 1.8 2.9 0.1 3.0 1.7 2.3 0.4 0.1 1.0 1.3 0.9 1.9 0.1 0.0 2.5 10.8 1.7 0.1 0.9 0.4 43.5 1.9 1.5 35.6 10.5 0.0 74.7 0.4 0.0 118.8 9.9 1.3 2.2 0.3 0.6 5.6 4.4 1.7 0.3 0.6 0.5 0.1 3.6 1.1 1.1 0.6 0.9 0.4 1.2 0.7 0.7 0.2 0.4 0.6 0.4 0.1 0.0 0.7 0.4 0.2 0.1 1.5 0.6 0.2 0.4 0.4 0.2 1.0 0.7 0.6 3.6 0.7 1.9 0.7 0.9 0.7 0.5 2.5 1.0 2.5 0.0 0.0 0.0 2.9 2.0 3.2 1.9 4.0 1.5 2.7 7.1 0.3 0.0 2.0 0.0 0.0 1.2 0.1 6.0 0.0 0.5 0.9 9.9 188.1 4.4 158.5 12.2 0.4 0.2 0.9 14.0 15.8 8.5 8.9 0.5 0.7 35.9 2.3 0.0 0.7 35.8 0.0 0.3 0.3 2.1 2.1 1.6 3.6 0.0 0.1 0.0 0.0 0.0 0.1 2.1 12.4 2.2 1.5 11.9 3.2 0.8 0.3 0.3 0.0 0.5 2.7 8.8 35.4 4.1 2.3 1.6 2.3 1.6 3.9 4.6 NPY PYY4 ENSG00000122585 "Neuropeptide Y" P01303 7 24284188-24291862 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Neuropeptide "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adrenal gland: 122.6;brain: 423.9;prostate: 332.8" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 56.7;Prostatic glandular cells: 100.6" "Cancer enriched" "Detected in many" 187 "prostate cancer: 1214.9" "Region enriched" "Detected in all" 7 "hypothalamus: 423.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 34 "SH-SY5Y: 700.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016733, CAB034368, HPA036636, HPA044572, HPA056798" Supported Supported Enhanced "Golgi apparatus" "Secreted to blood" NA NA 30700000 21000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "CAB016733: , CAB034368: AB_2298657, HPA036636: , HPA044572: AB_2678996, HPA056798: AB_2630371" "unprognostic (2.00e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (4.15e-1)" "unprognostic (3.76e-2)" "unprognostic (1.59e-2)" "unprognostic (1.87e-1)" "unprognostic (6.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.78e-1)" "unprognostic (2.52e-1)" 1.8 122.6 32.8 12.8 59.0 5.6 2.2 11.0 39.1 1.3 11.3 2.9 9.7 0.3 0.3 2.3 0.5 1.1 0.8 31.7 423.9 0.5 0.2 0.3 0.0 24.2 25.1 0.5 8.8 0.1 4.7 0.0 15.2 332.8 1.9 4.4 0.3 3.9 0.2 0.2 13.1 1.2 18.8 0.0 8.8 1.1 29.2 0.2 0.9 0.2 0.0 1.4 23.8 33.1 0.0 0.0 2.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.5 1.4 2.0 0.0 0.2 20.5 0.0 0.6 0.0 0.0 0.8 700.2 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 59.0 11.0 39.1 31.7 423.9 24.2 25.1 15.2 18.8 29.2 33.1 0.0 0.0 0.0 2.0 0.5 0.1 1.3 0.0 0.0 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.1 13.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 56.7 0.0 0.0 0.0 0.0 16.1 0.3 0.7 1.8 1.0 0.0 0.8 0.0 2.0 1.9 0.3 0.0 0.4 0.0 100.6 0.0 0.0 0.0 0.7 0.0 15.6 0.3 2.4 2.8 0.0 0.0 5.1 0.3 0.0 0.0 2.0 NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 37.3;brain: 38.3;epididymis: 34.4;retina: 38.0" "Group enriched" "Detected in many" 7 "Astrocytes: 612.5;Excitatory neurons: 764.5;Inhibitory neurons: 392.4;Oligodendrocyte precursor cells: 1259.2" "Cancer enriched" "Detected in all" 7 "glioma: 57.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.0" "Lineage enriched" "Detected in single" 15 "T-cells: 2.0" "Cell line enhanced" "Detected in many" "A549: 99.6;AF22: 94.8;EFO-21: 175.4;HMC-1: 187.9;SH-SY5Y: 115.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012606 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in brain" NA NA 110000000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Plasma membrane" "HPA012606: AB_1854636" "unprognostic (2.66e-1)" "unprognostic (2.65e-1)" "unprognostic (2.52e-3)" "unprognostic (2.18e-2)" "unprognostic (4.08e-3)" "unprognostic (1.01e-2)" "unprognostic (4.47e-3)" "unprognostic (1.66e-1)" "unprognostic (1.73e-1)" "unprognostic (4.81e-2)" "unprognostic (9.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.22e-2)" "unprognostic (9.70e-3)" "unprognostic (6.42e-2)" "unprognostic (6.51e-3)" "unprognostic (3.28e-2)" 3.1 37.3 19.8 1.8 31.9 0.3 1.5 2.4 34.6 5.0 0.0 0.8 0.7 2.1 34.4 0.7 3.6 7.3 0.4 33.1 9.4 6.2 0.4 2.3 0.8 2.3 22.7 1.5 29.4 7.3 11.4 7.8 2.0 0.8 0.7 38.0 1.9 14.2 0.2 0.8 0.6 0.7 1.5 4.8 1.8 1.7 38.3 2.8 4.1 0.4 2.7 0.5 0.4 2.6 0.1 99.6 94.8 0.0 11.4 2.2 1.8 0.7 0.4 1.0 1.7 40.7 0.0 0.0 175.4 0.7 1.5 0.4 2.2 1.6 1.0 0.1 12.7 0.0 0.7 1.0 0.2 0.9 187.9 15.5 0.0 0.2 0.6 0.2 61.7 0.2 0.2 0.8 1.5 38.2 0.4 0.3 13.1 60.1 0.0 0.0 27.8 33.3 21.4 0.1 18.6 115.9 1.3 0.0 1.9 3.3 0.2 0.1 66.2 4.2 1.0 0.1 16.4 0.2 0.5 0.9 0.7 0.1 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.2 19.8 31.9 2.4 34.6 33.1 9.4 2.3 22.7 2.0 1.5 38.3 2.6 0.2 0.0 0.0 612.5 0.8 0.4 0.1 0.8 1.2 66.2 1.5 0.9 0.7 7.2 0.1 5.5 102.2 3.6 0.0 0.2 3.9 1.6 37.3 10.4 2.4 1.3 0.0 0.0 764.5 12.1 0.2 2.0 3.6 25.0 23.4 4.4 1.4 0.4 0.8 13.5 392.4 0.3 0.0 0.8 0.4 8.3 0.9 0.2 3.6 51.5 0.6 45.1 0.0 1259.2 21.9 3.7 0.0 0.4 2.6 1.2 0.0 3.3 0.1 8.8 0.0 1.0 2.6 1.1 2.7 0.2 0.1 4.4 1.1 34.2 0.0 0.0 NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 17 "Excitatory neurons: 1466.4;Inhibitory neurons: 411.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Cell line enhanced" "Detected in many" "A549: 132.5;BJ: 91.3;fHDF/TERT166: 98.1;GAMG: 95.4;U-2197: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" 0.5 1.2 3.5 6.1 3.2 1.4 5.7 8.7 13.2 8.0 3.2 3.2 2.9 1.2 0.6 2.8 1.1 2.3 1.9 0.4 12.7 8.6 17.0 3.7 0.4 35.4 8.0 1.9 0.7 0.6 3.8 0.2 35.3 2.6 3.2 11.6 2.6 1.0 0.1 4.9 2.5 1.0 2.7 1.6 2.5 5.3 2.6 0.8 9.9 0.0 2.1 9.4 3.4 8.2 0.4 132.5 1.8 0.0 0.9 2.5 0.2 91.3 60.0 65.3 55.8 0.0 2.9 0.0 16.4 98.1 95.4 76.7 0.3 34.5 69.4 0.2 0.7 1.3 1.8 2.0 0.4 0.1 0.2 1.3 3.4 81.1 74.6 5.7 41.2 0.1 0.0 0.7 24.4 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.9 0.0 52.9 3.6 3.4 4.0 7.5 0.0 0.1 5.0 0.0 0.3 34.7 50.7 15.8 84.4 53.6 0.1 0.0 0.9 28.2 0.1 6.6 0.2 55.3 0.9 0.2 4.7 0.2 0.1 0.1 0.0 12.1 0.1 0.0 0.0 2.0 0.2 0.2 0.2 0.0 14.2 3.5 3.2 8.7 13.2 0.4 12.7 35.4 8.0 35.3 2.7 2.6 8.2 0.1 38.5 2.7 29.7 0.8 26.0 48.0 5.1 21.1 11.0 4.3 18.2 2.0 8.6 7.9 3.7 8.4 0.0 1.3 0.0 9.8 1.8 41.5 0.1 1.9 5.7 0.0 0.0 1466.4 0.2 0.0 10.5 0.0 0.2 1.3 3.2 7.1 5.3 0.5 28.6 411.8 0.0 2.0 10.2 1.9 23.5 0.3 22.1 1.8 36.5 49.2 5.0 0.0 54.3 19.2 0.9 0.0 0.4 0.0 42.9 0.0 18.7 2.4 3.1 0.0 0.1 9.3 11.3 5.0 3.2 6.1 0.0 0.6 0.0 0.0 6.5 NRG2 "Don-1, HRG2, NTAK" ENSG00000158458 "Neuregulin 2" O14511 5 139846779-140043299 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.5;Excitatory neurons: 89.9;Inhibitory neurons: 136.6;Oligodendrocyte precursor cells: 142.2;Oligodendrocytes: 50.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;HDLM-2: 4.0;Karpas-707: 4.4;PC-3: 11.1;RPTEC TERT1: 5.8;SCLC-21H: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038935, HPA047973" Approved Supported Nucleoplasm,Nucleoli "Secreted in other tissues" No NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Nucleoli "HPA038935: AB_10672833, HPA047973: AB_2680226" "unprognostic (8.66e-4)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (6.04e-2)" "unprognostic (3.22e-1)" "unprognostic (2.96e-2)" "unprognostic (8.66e-3)" "unprognostic (1.11e-1)" "unprognostic (3.99e-1)" "unprognostic (1.88e-1)" "unprognostic (4.26e-3)" "unprognostic (4.00e-2)" "unprognostic (7.79e-3)" "unprognostic (3.64e-3)" "unprognostic (9.54e-2)" "unprognostic (2.23e-2)" "unprognostic (2.07e-2)" 2.3 3.4 2.9 0.5 2.8 0.0 3.3 8.5 3.1 5.8 0.0 2.1 0.2 1.2 1.1 1.6 3.3 1.2 1.2 2.0 2.4 0.8 0.1 0.4 0.8 3.2 2.6 7.5 2.7 8.1 3.5 0.3 3.0 3.1 0.1 1.3 6.5 1.9 5.0 3.6 0.7 0.3 1.5 1.7 0.8 2.1 2.6 0.5 0.7 0.1 0.4 3.1 1.8 2.3 0.0 1.6 0.1 6.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.3 0.0 2.8 2.1 0.3 0.1 0.1 4.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.1 0.1 0.0 4.4 0.0 0.2 0.0 0.0 0.1 0.0 11.1 0.1 0.0 0.0 5.8 1.5 4.2 2.5 0.0 2.7 2.6 0.0 0.0 0.0 0.1 1.9 0.3 0.0 1.3 0.8 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.8 8.5 3.1 2.0 2.4 3.2 2.6 3.0 1.5 2.6 2.3 15.9 0.0 0.0 71.5 1.6 2.8 9.7 0.9 29.0 16.6 4.0 16.0 2.2 0.0 0.5 1.8 0.0 0.1 3.2 0.1 1.9 0.4 0.6 2.6 8.2 2.6 0.0 0.0 89.9 2.2 0.0 2.7 0.5 0.4 0.0 1.3 1.8 0.0 0.1 6.7 136.6 0.1 0.0 0.3 1.3 0.6 9.6 0.6 3.6 8.4 0.3 11.2 5.2 142.2 50.8 0.5 0.0 10.1 2.7 2.6 0.0 1.7 1.0 1.0 6.6 10.9 2.2 2.7 9.4 1.0 0.3 0.0 2.8 4.0 0.1 6.2 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 NRG4 HRG4 ENSG00000169752 "Neuregulin 4" Q8WWG1 15 75935969-76059795 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;retina: 4.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Early spermatids: 16.1;Exocrine glandular cells: 23.3;Gastric mucus-secreting cells: 31.1;Rod photoreceptor cells: 22.9" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "cerebellum: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.8;HL-60: 2.1;U-937: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010957 Uncertain "Secreted to digestive system" NA NA "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA010957: AB_1079504" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.67e-2)" "unprognostic (5.66e-2)" "unprognostic (4.10e-2)" "unprognostic (1.12e-2)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (2.82e-5)" "unprognostic (1.91e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-5)" "unprognostic (8.28e-2)" "unprognostic (7.45e-2)" "unprognostic (1.08e-2)" "unprognostic (2.06e-1)" 0.0 0.1 0.3 0.1 0.2 1.0 0.2 3.8 0.7 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.8 0.0 0.0 0.4 0.4 0.1 0.4 0.2 0.2 0.5 0.5 0.1 0.9 0.0 0.0 0.4 0.4 0.2 0.1 4.3 0.5 0.1 0.8 0.7 0.1 0.0 0.5 0.1 0.9 0.7 0.6 0.1 0.1 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.4 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.6 0.6 0.3 0.0 0.0 0.9 0.6 0.1 0.0 0.1 0.4 0.1 6.8 0.0 0.0 2.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.7 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.1 0.2 0.2 0.0 0.0 0.1 0.4 1.6 0.0 0.0 0.1 0.1 0.1 0.0 0.1 1.5 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 3.8 0.7 0.4 0.4 0.5 0.5 0.4 0.5 0.6 0.3 0.7 0.0 0.0 3.9 0.9 7.5 1.2 3.9 0.6 3.7 0.5 0.0 0.2 0.0 3.9 1.8 14.6 2.2 0.5 1.1 1.9 0.3 16.1 6.1 1.2 0.7 1.2 0.0 13.3 23.3 2.5 2.6 31.1 1.4 2.5 0.9 0.7 3.4 0.3 6.7 9.7 0.1 2.0 0.0 0.8 8.9 0.6 0.3 1.8 0.0 0.2 1.9 1.0 3.5 0.8 9.6 3.2 0.0 0.3 2.3 0.1 0.1 10.7 22.9 0.0 0.5 1.1 7.6 1.3 3.4 1.3 0.8 0.4 0.6 0.5 4.5 NRN1L "MRCC2446, UNQ2446" ENSG00000188038 "Neuritin 1 like" Q496H8 16 67884885-67888855 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 12.0;Astrocytes: 2.9;Bipolar cells: 2.0;Oligodendrocytes: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "BEWO: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041761 Uncertain "Secreted - unknown location" NA NA "Cluster 37: B-cells - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "HPA041761: AB_10961155" "unprognostic (2.79e-2)" "unprognostic (3.32e-1)" "unprognostic (1.19e-1)" "unprognostic (3.99e-2)" "unprognostic (4.85e-1)" 1.8 1.4 5.0 0.9 6.6 3.7 1.7 7.2 8.2 2.6 9.6 1.3 1.0 1.3 0.4 1.1 2.9 0.7 2.5 4.8 6.0 1.8 2.4 1.9 2.1 5.6 4.9 4.7 1.3 0.7 6.2 0.6 5.6 2.7 0.5 5.5 1.7 0.8 2.1 3.2 1.7 0.5 4.4 2.5 1.2 1.8 5.4 1.1 2.5 0.7 0.6 2.0 2.1 6.6 0.1 0.5 0.7 0.9 0.3 1.1 38.1 0.4 0.1 0.4 0.3 0.0 0.6 0.5 0.7 0.1 0.0 0.4 0.1 0.3 0.3 0.3 0.9 0.4 1.5 2.0 0.6 0.2 1.4 0.5 1.2 0.1 0.0 0.4 0.1 1.4 0.9 0.7 0.1 1.6 0.5 4.3 7.1 0.0 0.5 1.5 0.0 0.7 0.3 0.4 1.1 0.4 0.5 0.5 0.5 6.8 1.0 1.4 0.6 0.3 0.3 0.0 0.1 0.1 0.4 0.9 0.1 0.4 0.2 0.0 0.5 0.0 1.0 0.3 0.6 0.5 0.6 0.3 0.1 0.2 0.5 0.3 0.6 0.3 0.4 0.1 0.4 0.3 5.0 6.6 7.2 8.2 4.8 6.0 5.6 4.9 5.6 4.4 5.4 6.6 0.1 3.2 12.0 2.9 0.1 0.3 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.9 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.1 NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 366.0;Endothelial cells: 174.4;Hepatic stellate cells: 184.6;Sertoli cells: 282.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 444.6;hTERT-RPE1: 371.6;TIME: 369.5;U-87 MG: 425.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" 125.2 42.3 9.3 43.3 9.4 3.7 62.2 0.0 26.0 36.9 13.3 26.6 21.3 51.6 35.7 19.7 34.5 54.1 80.8 48.6 9.1 52.7 53.1 63.7 23.7 4.0 3.9 43.0 33.0 24.4 9.0 133.7 2.1 21.3 23.6 11.6 19.3 38.4 55.9 22.1 21.0 55.9 5.7 66.7 18.6 12.9 13.4 18.2 49.7 46.6 12.4 35.3 20.0 10.7 57.4 217.8 11.1 1.1 204.8 224.7 1.3 224.4 216.2 109.6 118.2 28.9 132.4 1.1 26.6 444.6 116.8 15.8 13.8 65.2 89.3 0.7 11.2 0.6 24.5 48.7 74.3 20.8 1.6 277.3 11.2 261.7 116.8 371.6 304.0 1.4 0.7 1.4 221.3 96.8 1.4 3.9 5.5 11.9 204.2 9.6 24.8 1.2 109.7 1.3 5.1 2.7 23.0 17.5 0.9 9.2 1.0 3.3 369.5 156.4 36.9 193.0 153.8 0.7 1.1 0.7 425.2 26.4 143.5 0.4 2.5 0.5 0.6 0.4 1.0 0.7 0.7 0.6 2.3 0.6 0.6 0.6 0.4 1.2 0.3 39.3 0.6 0.9 9.3 9.4 0.0 26.0 48.6 9.1 4.0 3.9 2.1 5.7 13.4 10.7 366.0 0.0 20.2 80.3 4.3 15.7 10.6 5.5 7.4 10.5 4.2 5.5 67.6 28.6 13.0 18.4 4.2 61.5 29.4 0.6 1.9 57.9 1.3 11.3 116.9 174.4 4.2 3.2 105.4 18.9 13.4 58.5 6.6 11.0 7.6 62.3 184.6 12.5 135.4 0.0 14.4 1.8 16.2 62.7 33.3 5.5 42.3 46.0 12.4 78.7 5.8 3.4 0.0 11.6 2.3 15.4 0.0 21.1 1.6 4.1 3.0 59.8 5.4 0.9 282.7 13.1 117.9 0.2 1.3 2.7 10.5 67.2 3.8 61.1 1.5 3.3 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NRTN NTN ENSG00000171119 Neurturin Q99748 19 5823802-5828324 "Disease related genes, Predicted secreted proteins" "Growth factor" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 25.6;pancreas: 16.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.2;Cone photoreceptor cells: 12.5;Endometrial ciliated cells: 14.9;Hepatocytes: 12.3;Rod photoreceptor cells: 50.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 8.2;K-562: 8.1;REH: 21.0;SH-SY5Y: 10.8;U-266/70: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA065260 Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 14: REH - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA065260: AB_2685448" "unprognostic (4.85e-2)" "unprognostic (1.66e-2)" "unprognostic (2.96e-2)" "prognostic favorable (3.86e-4)" "unprognostic (1.60e-2)" "prognostic favorable (7.23e-4)" "unprognostic (8.21e-3)" "unprognostic (5.60e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.38e-1)" "unprognostic (2.08e-2)" "unprognostic (1.28e-2)" "unprognostic (6.78e-3)" "unprognostic (3.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.22e-1)" "unprognostic (4.32e-2)" 0.3 8.2 0.1 0.4 0.2 0.0 0.8 0.4 0.5 1.5 0.4 9.6 1.2 0.4 0.6 4.4 1.1 0.5 25.6 0.2 0.2 2.8 14.4 0.8 0.0 0.5 0.5 0.1 16.9 1.5 1.1 0.2 0.6 2.8 0.2 9.7 5.3 0.9 0.0 6.1 3.1 0.9 0.1 0.2 9.4 1.3 0.4 0.4 0.4 0.0 0.2 4.6 3.0 0.4 0.6 0.8 0.9 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.9 0.0 0.5 0.1 3.2 0.0 0.0 8.2 5.7 0.0 0.0 2.6 0.9 0.1 2.1 0.1 0.8 0.0 0.0 0.0 0.0 2.7 8.1 0.0 0.0 1.7 0.7 0.9 2.6 1.2 2.0 21.0 2.6 4.9 0.3 0.0 0.5 10.8 0.2 1.0 1.2 0.3 0.4 0.7 0.0 0.0 1.6 0.0 0.0 11.5 2.6 0.7 0.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.2 0.4 0.5 0.2 0.2 0.5 0.5 0.6 0.1 0.4 0.4 0.3 0.0 1.8 0.3 0.4 1.9 1.4 0.4 1.8 4.6 3.0 6.9 17.2 1.5 0.1 3.7 12.5 0.1 0.4 1.0 3.9 0.3 0.1 14.9 4.3 0.6 1.2 0.0 0.5 0.7 0.0 1.3 2.0 2.6 0.0 1.1 3.6 12.3 0.3 0.0 0.7 1.8 0.0 0.3 0.2 0.6 0.9 0.3 5.4 0.0 0.1 6.0 1.0 0.5 1.0 0.7 0.1 0.0 2.5 1.0 0.2 0.7 0.2 50.0 0.0 0.0 0.9 0.4 3.4 1.4 4.5 0.1 0.6 0.5 1.4 1.1 NT5DC3 "FLJ11266, TU12B1-TY" ENSG00000111696 "5'-nucleotidase domain containing 3" Q86UY8 12 103770453-103841234 "Metabolic proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 80.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 41.2;Excitatory neurons: 36.6;Oligodendrocyte precursor cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041634 Approved Mitochondria,Cytosol "Secreted - unknown location" NA NA "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Mitochondria Cytosol "HPA041634: AB_10795597" "unprognostic (2.61e-2)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (2.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.57e-1)" "unprognostic (2.19e-1)" "unprognostic (2.45e-2)" "unprognostic (5.43e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.60e-3)" "unprognostic (7.42e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.11e-4)" 2.9 4.0 14.2 1.9 12.0 17.5 3.3 0.0 13.3 9.3 0.0 80.5 1.0 23.1 5.0 5.2 3.7 1.4 1.9 23.3 7.8 2.0 5.0 2.8 1.3 1.5 1.8 2.9 3.5 0.8 4.5 1.5 1.4 7.5 7.7 2.3 4.1 5.4 7.8 2.5 4.7 6.8 1.2 1.6 6.6 3.1 8.9 0.6 1.9 3.3 1.2 21.7 5.7 4.8 3.6 6.5 3.6 4.2 5.1 4.0 6.8 5.9 3.5 4.1 2.6 4.4 0.9 6.1 1.1 7.0 4.5 4.1 5.2 11.7 5.9 4.5 4.2 7.6 2.5 5.2 2.8 4.1 1.9 3.5 2.5 5.3 22.7 8.3 2.4 3.0 12.2 3.0 9.2 3.3 3.6 6.6 4.5 5.2 6.9 4.9 6.3 2.3 6.5 2.4 4.9 2.0 4.9 5.4 7.1 3.3 3.1 3.8 3.2 4.0 4.8 5.5 11.9 2.7 3.5 4.4 3.8 6.2 6.0 0.4 0.5 0.0 0.6 0.6 1.2 1.3 0.9 0.5 1.5 1.4 0.7 0.6 0.9 0.6 0.4 1.9 0.2 0.3 14.2 12.0 0.0 13.3 23.3 7.8 1.5 1.8 1.4 1.2 8.9 4.8 1.4 0.0 2.3 3.9 2.7 4.5 21.9 3.0 21.6 2.0 5.6 7.4 3.8 2.8 2.1 1.8 0.0 5.2 2.7 5.8 0.0 2.1 12.1 14.0 11.9 1.7 41.2 1.3 36.6 2.0 4.7 3.8 7.7 19.4 0.0 3.7 0.7 5.3 1.8 10.1 24.4 11.4 10.2 4.1 6.5 10.5 5.0 2.8 0.0 6.5 2.9 0.8 1.0 29.1 2.7 2.7 2.2 8.2 2.7 13.0 1.1 2.1 6.9 5.0 0.0 5.6 5.7 0.4 3.1 9.0 4.4 4.1 2.5 4.1 9.2 9.8 NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.5;Basal prostatic cells: 36.6;Basal squamous epithelial cells: 89.4;Prostatic glandular cells: 20.5;Sertoli cells: 32.9;Smooth muscle cells: 24.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in some" 5 "cerebellum: 3.4;cerebral cortex: 1.3;hippocampal formation: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.4;BJ hTERT+ SV40 Large T+: 14.8;BJ hTERT+ SV40 Large T+ RasG12V: 19.7;HBF TERT88: 18.0;RT4: 8.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 4.7;cerebral cortex: 2.0;hippocampal formation: 2.2" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA032001: AB_2674106" "unprognostic (3.04e-2)" "unprognostic (7.46e-2)" "unprognostic (7.33e-3)" "unprognostic (4.66e-3)" "unprognostic (8.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-3)" "unprognostic (7.68e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (2.20e-1)" "unprognostic (7.77e-4)" "unprognostic (4.02e-3)" "unprognostic (1.92e-1)" "unprognostic (8.06e-3)" "unprognostic (4.51e-3)" 4.2 1.8 0.2 0.7 0.4 0.0 2.7 3.4 1.3 6.6 0.2 1.8 1.9 1.9 2.0 3.4 2.9 1.8 3.1 1.2 0.3 2.6 7.7 1.6 0.3 0.4 0.2 11.1 0.2 0.1 1.0 1.9 0.3 3.6 1.0 0.1 3.1 2.4 1.8 3.2 2.5 0.9 0.3 4.5 2.5 0.8 0.1 0.4 0.9 1.0 0.4 4.6 7.0 0.2 1.9 0.0 6.7 0.0 0.0 0.0 0.0 4.5 11.4 14.8 19.7 0.1 0.2 0.0 6.7 7.3 0.0 2.4 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 4.5 4.7 8.5 0.3 0.0 0.0 0.1 0.0 3.9 0.0 0.0 0.0 0.0 3.1 0.2 0.0 0.2 0.1 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 3.4 1.3 1.2 0.3 0.4 0.2 0.3 0.3 0.1 0.2 1.0 0.0 0.0 0.0 0.0 18.5 36.6 0.7 89.4 0.0 0.2 10.3 0.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.2 1.4 0.0 0.0 0.1 0.0 0.1 6.1 0.0 0.1 0.0 0.0 5.0 2.1 0.0 0.0 1.2 0.1 0.0 0.0 2.1 0.1 8.4 0.3 7.2 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 10.9 0.0 20.5 0.2 0.0 0.8 0.0 32.9 6.8 24.0 0.5 0.8 5.0 3.3 0.1 0.5 0.5 0.2 6.9 NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.1;skeletal muscle: 17.1;skin 1: 31.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 35.6;Basal respiratory cells: 24.0;Basal squamous epithelial cells: 15.4;Breast myoepithelial cells: 24.3;Club cells: 9.5;Cytotrophoblasts: 13.6;Urothelial cells: 11.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 31.1;HBEC3-KT: 11.7;hTCEpi: 50.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA049376: AB_2680735" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" "unprognostic (9.27e-4)" "unprognostic (1.76e-4)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.87e-3)" "unprognostic (3.90e-4)" "unprognostic (2.97e-1)" "unprognostic (1.40e-3)" "unprognostic (3.71e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-2)" "unprognostic (2.46e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 4.3 0.7 0.0 0.0 0.1 3.7 10.8 2.5 0.0 1.0 0.1 0.0 0.1 0.0 3.5 0.0 0.1 0.2 0.2 0.0 0.0 1.6 3.2 0.1 20.1 0.0 0.0 8.2 7.1 17.1 31.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.9 1.5 2.5 1.1 6.5 9.6 0.1 3.9 0.2 0.3 2.1 0.0 0.0 9.3 0.0 0.0 0.1 0.0 3.4 13.8 0.0 3.5 0.0 0.5 31.1 0.1 11.7 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 50.4 0.0 1.6 3.1 0.0 0.1 0.0 0.2 0.4 1.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 8.8 0.0 0.1 0.7 0.1 0.0 4.3 8.0 0.1 0.2 1.8 3.5 0.2 9.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 3.2 0.0 0.0 0.0 7.0 35.6 24.0 15.4 0.0 3.4 24.3 0.4 0.0 9.5 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 5.7 0.0 0.0 0.0 0.9 0.0 1.3 1.7 3.1 2.7 0.3 0.1 0.0 11.9 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 NTN3 NTN2L ENSG00000162068 "Netrin 3" O00634 16 2471297-2474145 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 2.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HeLa: 1.7;REH: 5.0;SCLC-21H: 5.8;SH-SY5Y: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050817 Uncertain "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA050817: AB_2681247" "unprognostic (2.60e-2)" "unprognostic (1.95e-2)" "unprognostic (1.79e-1)" "unprognostic (9.17e-2)" "unprognostic (6.44e-2)" "unprognostic (2.23e-2)" "unprognostic (9.62e-3)" "unprognostic (2.11e-1)" "unprognostic (4.55e-2)" "unprognostic (6.95e-2)" "unprognostic (5.58e-2)" "unprognostic (2.34e-1)" "unprognostic (1.35e-2)" "unprognostic (3.26e-2)" "unprognostic (6.68e-2)" "unprognostic (2.39e-2)" "unprognostic (6.61e-2)" 0.1 0.0 2.2 0.0 1.2 0.0 0.0 0.5 1.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.1 2.3 0.0 0.2 0.0 0.0 2.1 2.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.7 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.7 0.1 0.0 0.0 5.0 0.1 0.1 0.0 0.0 5.8 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.3 0.2 0.4 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.2 0.5 1.6 1.1 2.3 2.1 2.0 0.8 1.5 2.7 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 181.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 198.6;Hepatic stellate cells: 369.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 513.8;hTERT-HME1: 205.8;PC-3: 189.6;TIME: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA049832 Approved "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA049832: AB_2680905" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (2.85e-1)" "prognostic favorable (8.12e-9)" "unprognostic (3.52e-2)" "unprognostic (7.08e-2)" "unprognostic (1.93e-1)" "prognostic favorable (6.67e-5)" 24.4 17.3 6.4 5.7 7.5 0.1 72.9 4.4 10.5 26.5 12.0 16.5 12.0 12.7 15.3 15.6 34.4 22.4 66.8 8.9 5.7 107.6 26.7 70.2 2.9 5.9 8.7 86.1 62.5 13.3 7.6 11.9 5.7 42.4 18.1 0.6 32.6 59.1 12.6 8.8 17.5 15.0 6.1 181.5 48.7 12.1 6.2 6.2 14.4 19.9 6.5 49.5 14.4 8.7 26.7 71.3 2.0 0.1 28.5 45.0 3.0 49.7 513.8 67.1 78.2 56.1 48.8 0.0 3.5 105.3 88.1 42.2 0.6 15.3 34.0 0.0 4.3 2.3 12.7 11.1 1.7 0.0 0.1 1.1 43.5 75.0 205.8 72.9 133.3 0.4 0.0 0.1 25.4 20.0 0.2 0.3 1.1 7.9 189.6 0.2 0.6 0.1 64.8 133.4 0.3 0.6 60.5 77.1 1.3 2.3 22.2 0.1 289.3 25.9 9.5 101.3 5.2 0.1 0.1 0.0 5.9 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 7.5 4.4 10.5 8.9 5.7 5.9 8.7 5.7 6.1 6.2 8.7 31.9 41.7 123.2 6.2 3.8 4.7 120.5 15.2 39.3 1.8 77.6 55.4 44.8 44.3 30.8 198.6 0.0 6.2 1.3 4.4 5.9 36.7 10.3 36.4 3.2 35.5 0.0 2.7 28.1 28.0 3.6 33.7 23.0 28.1 1.3 25.9 369.5 10.2 0.4 0.0 70.6 37.2 4.1 26.3 3.7 3.8 2.1 2.6 7.2 20.6 0.6 0.3 0.0 112.6 1.8 36.7 4.0 3.4 0.9 108.9 1.5 84.3 38.0 0.2 26.3 119.0 73.9 1.9 0.6 5.9 2.3 1.6 3.3 1.4 6.4 127.0 NTN5 ENSG00000142233 "Netrin 5" Q8WTR8 19 48661407-48673081 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pituitary gland: 5.1" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Bipolar cells: 5.4;Early spermatids: 9.2;Horizontal cells: 8.4;Late spermatids: 11.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Region enriched" "Detected in single" 5 "cerebellum: 4.8" "Secreted in brain" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "unprognostic (5.26e-6)" "unprognostic (4.48e-2)" "unprognostic (2.23e-1)" "unprognostic (4.33e-2)" "unprognostic (3.18e-2)" "unprognostic (1.73e-2)" "unprognostic (2.89e-3)" "unprognostic (9.40e-3)" "unprognostic (1.74e-3)" "unprognostic (4.60e-1)" "unprognostic (5.11e-2)" "unprognostic (1.60e-3)" "unprognostic (3.51e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-3)" 0.3 0.4 2.0 0.2 2.2 0.3 1.2 1.6 2.8 1.4 0.6 0.6 0.2 1.0 0.5 0.5 3.2 0.7 0.3 1.9 1.4 0.8 0.4 0.4 0.8 1.9 1.8 2.3 0.4 0.5 5.1 0.0 1.5 2.8 0.0 1.2 1.0 0.8 0.2 1.2 0.6 0.1 1.7 0.9 0.3 0.6 1.8 0.6 1.9 0.1 0.3 0.4 0.8 2.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.5 0.2 0.0 0.0 0.6 0.0 0.2 0.9 0.1 0.0 0.0 0.3 0.2 0.4 0.0 1.2 0.0 0.3 0.3 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.2 1.6 2.8 1.9 1.4 1.9 1.8 1.5 1.7 1.8 2.2 1.1 0.0 0.0 4.6 0.1 0.5 0.4 0.1 0.0 5.4 0.8 1.9 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.1 9.2 0.5 1.3 0.6 0.0 0.0 1.1 0.0 0.0 0.4 0.0 1.0 0.0 2.3 0.4 0.1 0.1 8.4 0.6 0.1 0.0 0.0 0.4 11.8 0.6 0.1 1.8 1.0 0.0 1.6 1.0 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 2.8 0.0 0.7 0.4 3.1 0.2 0.1 0.1 0.1 0.2 3.1 0.0 0.2 NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 165.8" "Cell type enriched" "Detected in some" 13 "Intestinal goblet cells: 1683.2" "Cancer enhanced" "Detected in many" "lung cancer: 155.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 205.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 154.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" NA NA 1600000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "HPA026664: AB_2671936, HPA071012: " "unprognostic (3.63e-1)" "prognostic favorable (9.94e-5)" "unprognostic (8.18e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-3)" "unprognostic (8.83e-2)" "unprognostic (1.74e-2)" "unprognostic (3.76e-2)" "unprognostic (1.30e-6)" "unprognostic (2.94e-2)" "unprognostic (2.25e-1)" "unprognostic (2.17e-1)" "unprognostic (7.48e-2)" 6.2 1.2 3.3 3.6 0.6 0.0 5.2 0.9 8.4 0.7 0.5 1.8 6.6 0.3 0.7 5.6 0.9 1.3 0.9 2.5 18.1 1.7 1.4 1.2 11.7 11.7 10.2 0.6 0.4 0.1 32.3 0.5 6.2 0.3 1.5 0.0 0.1 0.6 0.0 0.2 165.8 1.1 3.2 0.1 36.4 0.3 26.8 0.5 0.8 0.2 1.0 3.1 0.3 3.6 0.0 5.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 50.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 10.7 0.0 4.1 0.0 1.7 0.0 0.0 0.0 5.4 1.6 0.0 0.0 0.0 205.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.6 0.9 8.4 2.5 18.1 11.7 10.2 6.2 3.2 26.8 3.6 3.6 0.0 0.5 0.0 0.0 1.3 0.7 22.6 0.0 0.0 10.1 0.0 0.3 0.0 27.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.4 2.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 44.3 0.0 0.2 0.0 1.2 1683.2 2.0 0.3 2.6 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.5 15.0 0.0 0.0 2.5 120.8 0.0 3.5 0.0 0.0 0.0 0.9 0.8 0.1 1.2 2.3 0.1 1.3 0.0 8.1 60.4 NUCB1 "Calnuc, NUC" ENSG00000104805 "Nucleobindin 1" Q02818 19 48900312-48923372 "Plasma proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 453.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008176 Supported Supported "Golgi apparatus,Microtubules" "Secreted to blood" NA NA 27000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" Microtubules "HPA008176: AB_1845923" "unprognostic (2.13e-1)" "unprognostic (2.83e-1)" "unprognostic (4.36e-3)" "unprognostic (6.28e-2)" "unprognostic (1.06e-2)" "unprognostic (2.95e-1)" "unprognostic (6.86e-2)" "unprognostic (1.98e-1)" "unprognostic (9.51e-2)" "unprognostic (8.14e-3)" "unprognostic (2.34e-3)" "unprognostic (9.89e-2)" "unprognostic (5.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.39e-1)" "unprognostic (8.90e-3)" "unprognostic (3.41e-1)" 181.3 103.5 55.8 106.8 60.4 82.3 141.6 65.5 68.1 115.0 79.4 122.1 179.9 127.6 61.3 111.2 116.9 108.3 204.0 58.2 63.0 154.6 264.5 157.1 82.1 65.9 62.9 125.6 130.1 173.5 69.5 114.8 67.5 109.2 54.8 30.2 117.8 103.0 180.1 96.6 163.6 106.0 57.7 111.1 118.8 34.7 73.1 49.5 122.2 110.7 53.1 130.1 108.9 61.6 54.8 182.1 84.2 188.5 304.6 249.2 97.6 208.1 189.9 103.3 144.2 92.9 203.1 54.7 151.8 250.6 98.9 132.0 48.6 107.0 43.3 194.6 90.3 141.6 119.0 131.6 156.6 85.1 183.6 288.0 52.1 96.8 62.9 275.2 167.2 60.7 173.1 278.8 107.0 71.6 42.3 68.6 42.2 132.1 93.5 78.7 125.3 114.9 90.2 134.6 61.2 123.2 247.1 152.2 88.1 79.7 78.8 112.1 234.6 172.3 114.3 107.0 99.3 210.8 501.1 37.1 132.5 54.3 207.3 102.9 108.5 105.7 100.6 128.5 75.3 46.8 67.5 77.2 79.0 37.3 55.3 56.7 104.7 69.2 114.2 113.9 74.6 129.5 55.8 60.4 65.5 68.1 58.2 63.0 65.9 62.9 67.5 57.7 73.1 61.6 154.5 41.7 72.1 17.6 51.0 48.3 67.2 81.3 66.0 21.7 57.6 57.5 58.0 78.6 51.5 69.9 14.6 101.5 69.6 153.0 41.1 148.0 10.8 27.4 65.5 116.0 74.4 54.5 14.5 118.3 150.9 126.7 76.0 50.2 95.2 64.1 122.0 149.2 213.7 20.2 18.9 109.9 69.2 138.3 74.6 9.3 110.3 101.9 101.4 17.8 120.3 52.6 74.2 8.5 11.8 100.0 149.2 124.1 126.3 63.8 453.3 135.4 24.4 20.5 92.1 51.0 79.0 21.9 37.6 65.6 49.9 102.1 73.0 103.9 123.3 68.1 NUCB2 NEFA ENSG00000070081 "Nucleobindin 2" P80303 11 17208153-17349980 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 758.3;salivary gland: 771.4" "Cell type enhanced" "Detected in all" "Early spermatids: 690.6;Late spermatids: 508.5;Respiratory ciliated cells: 618.8;Syncytiotrophoblasts: 1158.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 1867.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008395, CAB015931, CAB079781" Enhanced Supported Enhanced "Golgi apparatus" "Secreted to blood" NA NA 1250000 690000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus" "CAB015931: , CAB079781: AB_2313672, HPA008395: AB_1854683" "unprognostic (2.49e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.27e-6)" "unprognostic (5.24e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-3)" "unprognostic (3.66e-3)" "unprognostic (1.81e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.46e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" 56.2 75.7 23.9 62.1 27.8 619.9 141.1 28.8 32.1 137.2 58.0 68.3 57.3 60.8 458.2 146.3 107.2 60.8 95.7 22.8 34.7 43.2 102.2 49.8 60.2 25.7 28.2 56.0 758.3 479.1 113.0 90.9 26.8 70.9 68.4 64.5 771.4 190.9 38.5 21.1 40.7 78.5 26.2 42.2 92.9 119.2 28.4 334.2 153.9 30.4 78.5 61.8 44.9 26.6 119.9 49.0 53.7 163.4 118.9 162.3 65.0 260.5 381.0 115.1 203.0 48.7 26.8 182.9 63.5 250.7 107.1 50.1 34.4 66.8 178.7 126.7 76.3 135.8 57.8 85.2 340.5 1867.0 238.6 71.1 86.8 82.9 200.9 284.9 143.3 672.1 120.1 361.1 114.9 105.9 656.2 670.3 12.9 194.0 50.5 239.8 130.4 15.1 51.9 37.5 63.5 35.4 114.6 114.2 61.4 78.0 93.5 498.1 128.1 120.9 110.9 369.1 112.1 70.3 41.3 101.1 140.5 646.1 106.4 210.5 43.5 168.2 94.1 30.5 122.9 22.7 88.5 173.7 40.6 14.5 246.7 271.2 39.3 277.9 25.6 426.0 42.7 119.8 23.9 27.8 28.8 32.1 22.8 34.7 25.7 28.2 26.8 26.2 28.4 26.6 118.7 44.8 70.4 16.3 54.8 27.5 60.2 156.3 14.8 71.0 152.8 87.0 193.8 55.8 176.5 42.3 54.2 127.1 136.5 17.6 27.4 91.1 690.6 112.4 92.9 94.7 42.4 137.8 21.9 132.6 319.1 148.8 40.2 97.0 67.6 80.0 108.5 141.8 70.7 35.3 23.5 189.0 189.2 29.4 40.0 508.5 149.8 37.6 69.4 18.7 24.1 111.2 95.8 13.6 10.8 75.2 13.2 114.3 256.5 108.7 3.9 28.5 618.8 99.3 46.0 50.8 75.4 174.9 61.3 87.7 30.1 1158.2 92.3 88.3 45.3 61.2 NXPE3 "FAM55C, MGC15606" ENSG00000144815 "Neurexophilin and PC-esterase domain family member 3" Q969Y0 3 101779202-101828231 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.2;tongue: 50.5" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 177.7;Plasma cells: 59.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 92.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036259 Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA036259: AB_10671838" "unprognostic (3.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (4.42e-5)" "unprognostic (4.98e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (7.42e-2)" "unprognostic (1.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.57e-3)" "unprognostic (3.43e-1)" "prognostic unfavorable (7.76e-6)" "unprognostic (2.89e-1)" "unprognostic (5.23e-2)" "unprognostic (1.77e-1)" "unprognostic (8.75e-3)" 7.8 6.4 13.6 11.7 23.2 12.5 6.0 20.1 18.7 7.6 1.3 5.3 3.5 8.1 3.3 6.1 7.4 6.5 18.4 12.4 21.0 3.3 3.5 9.4 16.7 21.6 21.3 7.1 2.5 20.7 6.8 6.7 24.2 8.3 4.6 11.3 3.5 9.8 73.2 2.0 5.0 10.6 16.5 12.5 5.0 7.4 23.7 13.1 5.9 50.5 14.2 7.2 4.5 34.8 19.8 29.9 25.1 9.2 26.6 26.9 5.7 21.7 27.2 25.4 36.6 7.0 2.0 29.3 62.6 24.4 30.4 4.1 28.3 23.2 31.2 36.7 8.9 22.7 19.0 19.3 35.0 19.4 19.9 15.6 3.9 21.1 7.8 33.1 27.8 27.3 4.7 92.0 42.5 10.6 26.2 4.6 14.6 1.0 18.6 11.5 30.7 12.7 18.8 5.1 19.6 23.4 9.3 2.2 16.7 14.9 4.3 27.2 24.5 28.0 33.7 3.3 23.0 43.0 47.5 34.0 23.9 83.7 5.4 8.0 16.5 20.1 14.6 13.0 10.0 10.8 16.0 15.2 14.2 6.4 21.6 17.6 8.6 8.9 12.7 8.8 20.8 14.1 13.6 23.2 20.1 18.7 12.4 21.0 21.6 21.3 24.2 16.5 23.7 34.8 24.1 25.6 5.1 11.4 19.2 3.7 2.2 2.3 6.2 26.1 9.8 9.0 49.4 4.3 2.3 0.0 8.4 0.7 12.8 1.0 0.0 2.6 1.4 2.9 11.8 17.2 7.2 0.0 34.1 2.6 1.6 10.0 1.5 1.9 13.3 46.0 40.4 1.8 6.8 48.8 35.2 0.6 4.1 19.1 10.0 1.8 9.3 11.0 7.2 9.4 26.3 22.7 23.7 44.2 177.7 2.9 0.1 7.5 59.6 1.0 0.8 0.8 3.1 17.1 19.7 14.9 8.3 11.8 15.1 3.8 3.0 0.7 16.2 20.0 0.9 1.1 NXPE4 "C11orf33, FAM55D, FLJ20127" ENSG00000137634 "Neurexophilin and PC-esterase domain family member 4" Q6UWF7 11 114570591-114595786 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 119.6;salivary gland: 77.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 95.5;Intestinal goblet cells: 88.1;Paneth cells: 41.8;Undifferentiated cells: 115.8" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 13.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042801 Approved "Secreted to digestive system" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA042801: AB_10793986" "unprognostic (1.35e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-3)" "unprognostic (1.27e-1)" "unprognostic (3.51e-3)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (7.47e-3)" "unprognostic (4.36e-2)" "unprognostic (2.05e-1)" 0.1 0.0 0.1 7.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 114.2 0.6 0.2 6.8 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 5.3 119.6 0.0 77.2 0.2 0.0 0.0 0.7 5.2 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 0.0 0.0 0.5 0.0 0.0 0.0 17.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 41.8 0.0 0.1 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 115.8 0.2 NXPH1 ENSG00000122584 "Neurexophilin 1" P58417 7 8433609-8752961 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "adrenal gland: 42.0;brain: 25.5" "Group enriched" "Detected in some" 40 "Inhibitory neurons: 1486.5;Oligodendrocyte precursor cells: 1500.4" "Group enriched" "Detected in some" 62 "breast cancer: 2.3;glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Karpas-707: 10.9;WM-115: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.74e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-2)" "unprognostic (1.46e-4)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (5.32e-1)" "unprognostic (9.46e-2)" 0.1 42.0 9.6 0.0 11.0 0.0 0.4 4.0 8.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 13.9 0.0 0.0 0.0 0.0 13.4 25.5 0.0 0.0 0.0 1.5 0.0 12.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 24.9 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.0 4.0 8.7 8.6 13.9 13.4 25.5 12.1 6.3 24.9 5.5 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1486.5 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 36.5 0.0 0.6 0.0 1500.4 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.1 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;kidney: 4.1;ovary: 8.1" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 156.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.7;midbrain: 7.6;pons: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.4;SiHa: 3.0;SuSa: 2.1;U-2 OS: 4.7;U-251 MG: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" NA Yes "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" 0.2 0.0 1.8 0.1 1.7 0.0 0.1 1.0 1.8 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.0 0.4 4.1 0.0 0.0 0.0 11.7 7.6 8.1 0.0 0.0 0.1 0.1 13.1 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.6 3.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 4.7 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.0 1.8 1.0 0.4 11.7 7.6 13.1 1.9 1.1 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 156.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NXPH3 NPH3 ENSG00000182575 "Neurexophilin 3" O95157 17 49575871-49583827 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Bipolar cells: 23.3;Fibroblasts: 7.6;Muller glia cells: 8.5;Peritubular cells: 14.3;Smooth muscle cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 11.4;BJ: 3.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 41.1" HPA073819 Approved "Vesicles,Mitotic spindle" "Secreted in brain" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Mitotic spindle" "HPA073819: " "unprognostic (2.39e-2)" "unprognostic (4.75e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-1)" "unprognostic (1.92e-1)" "unprognostic (3.30e-1)" "unprognostic (1.97e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-2)" "unprognostic (6.33e-2)" "unprognostic (4.62e-4)" "unprognostic (2.59e-2)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (5.05e-3)" 3.9 0.9 1.8 1.0 1.8 0.0 2.9 16.4 3.5 9.0 0.7 11.0 0.4 12.0 0.6 1.5 7.0 1.7 2.9 3.5 0.5 0.4 0.1 2.7 0.5 6.3 3.8 5.2 0.6 1.3 7.5 1.3 6.4 5.9 0.3 0.6 3.1 4.7 1.2 2.3 1.7 2.5 0.1 1.0 3.4 1.6 3.9 0.3 1.4 2.0 0.3 8.9 6.9 3.0 0.0 0.0 0.1 0.0 0.0 0.2 11.4 3.2 0.4 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 16.4 3.5 3.5 0.5 6.3 3.8 6.4 0.1 3.9 3.0 0.5 0.0 1.3 14.0 0.0 0.4 0.3 0.2 0.6 23.3 0.9 0.5 1.7 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.6 0.0 0.0 2.5 0.2 3.2 7.6 0.0 0.5 0.0 0.0 6.4 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.4 0.0 4.4 0.3 1.8 0.0 4.2 8.5 0.0 2.5 0.5 0.0 0.0 14.3 0.7 0.3 0.0 0.0 0.0 1.2 0.0 0.8 8.9 0.1 1.3 0.0 1.1 0.1 0.2 0.1 0.0 0.1 NXPH4 NPH4 ENSG00000182379 "Neurexophilin 4" O95158 12 57216794-57226449 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;skin 1: 19.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.5;Cytotrophoblasts: 29.0;Muller glia cells: 18.5;Suprabasal keratinocytes: 10.4;Syncytiotrophoblasts: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 76.8;RH-30: 62.3;RPMI-8226: 43.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in brain" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.08e-2)" "unprognostic (4.84e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (6.21e-4)" "prognostic unfavorable (5.42e-4)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (3.07e-1)" "unprognostic (1.51e-2)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (6.77e-2)" "prognostic unfavorable (7.68e-6)" "unprognostic (7.83e-2)" "unprognostic (2.73e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-3)" 2.5 0.6 6.3 0.3 4.1 0.4 0.7 8.3 3.6 2.3 0.6 0.1 0.0 0.0 0.2 3.0 0.1 0.0 2.7 8.3 13.8 0.7 0.8 0.3 0.5 13.3 7.1 0.0 1.5 1.7 0.3 2.7 18.4 4.4 0.0 5.0 4.0 0.0 0.2 19.4 0.2 0.1 7.5 0.4 0.1 1.2 7.1 0.1 0.4 0.0 0.3 0.1 2.8 5.0 18.1 1.4 0.4 76.8 8.6 2.2 7.1 4.9 11.5 2.1 2.7 5.0 0.9 19.4 7.6 5.1 3.2 16.2 10.3 2.4 0.6 3.4 20.6 0.1 0.6 0.3 7.4 0.7 2.5 2.0 4.0 2.0 3.2 2.5 0.0 1.2 0.8 20.0 1.5 18.6 0.0 0.0 0.7 0.4 13.5 1.0 62.3 43.1 0.0 3.2 12.3 0.7 11.0 22.5 23.2 0.2 22.4 0.6 0.0 5.4 17.8 2.3 5.8 10.8 2.3 6.9 3.5 9.6 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 4.1 8.3 3.6 8.3 13.8 13.3 7.1 18.4 7.5 7.1 5.0 0.8 0.0 0.0 0.7 8.0 14.5 0.4 1.1 3.4 4.7 0.7 0.9 0.8 0.0 0.7 0.0 8.4 29.0 0.3 0.1 0.0 0.8 0.0 0.1 0.4 0.5 7.2 0.0 0.7 0.0 1.9 1.1 0.5 0.1 0.0 1.1 0.0 0.1 2.0 1.7 1.4 0.0 2.0 0.0 0.8 0.0 0.0 0.4 3.6 0.0 0.0 18.5 0.0 0.0 0.1 0.6 0.0 0.4 0.3 3.3 0.0 0.0 1.0 0.5 0.0 2.4 3.6 0.7 4.5 1.8 10.4 29.3 0.4 0.0 0.0 0.4 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.9;Fibroblasts: 135.9;Hepatocytes: 218.8;Muller glia cells: 279.4;Theca cells: 149.0;Urothelial cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 115.5;Hep G2: 190.1;NB-4: 139.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" 66.0 91.5 47.7 18.0 56.8 10.8 42.6 35.8 57.1 66.7 40.5 61.9 47.7 54.2 16.0 22.8 54.6 34.5 55.1 48.1 36.5 51.4 396.6 19.2 5.8 39.0 37.8 61.0 74.1 6.7 27.4 8.1 37.1 33.5 36.5 30.7 53.9 13.7 13.2 12.0 57.3 29.1 35.9 54.4 33.5 3.7 45.0 4.6 25.9 12.2 3.7 42.6 40.4 44.6 24.9 7.5 30.9 14.4 47.8 53.4 1.7 47.7 53.8 20.5 30.0 7.5 37.3 0.0 115.5 35.6 33.7 25.7 8.9 13.2 8.2 18.7 21.1 21.1 4.7 190.1 42.4 46.7 7.9 66.8 7.9 19.8 54.8 39.9 59.7 12.7 14.0 22.7 5.0 9.4 0.3 139.9 11.6 7.3 40.8 11.8 0.9 23.7 31.8 13.4 1.5 10.0 14.0 15.2 40.2 8.6 4.8 74.7 32.7 39.3 14.7 40.8 4.6 0.8 0.7 0.4 30.3 76.2 14.1 0.0 3.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.1 0.0 0.3 0.5 0.1 0.8 47.7 56.8 35.8 57.1 48.1 36.5 39.0 37.8 37.1 35.9 45.0 44.6 19.4 0.0 0.6 102.2 3.7 9.4 33.6 7.3 12.5 3.2 6.0 7.0 5.5 34.3 3.5 71.7 2.1 2.1 1.1 135.9 27.4 14.8 0.2 4.7 70.9 40.0 22.8 12.8 0.6 28.7 5.5 135.9 11.7 12.2 1.3 2.6 12.5 218.8 6.0 0.0 2.3 56.5 4.1 11.5 20.9 1.1 16.8 11.0 16.0 23.4 10.2 279.4 0.0 5.5 11.0 28.2 56.5 4.5 14.5 31.3 111.1 79.3 0.4 10.6 52.6 8.6 40.8 0.7 6.9 11.3 10.2 6.2 3.1 149.0 45.8 192.5 OBP2A "hOBPIIa, LCN13, OBP" ENSG00000122136 "Odorant binding protein 2A" Q9NY56 9 135546126-135549969 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "fallopian tube: 24.9" "Cell type enhanced" "Detected in some" "Breast glandular cells: 2.4;Breast myoepithelial cells: 3.4;Late spermatids: 1.8;Leydig cells: 1.5;Melanocytes: 1.8" "Cancer enriched" "Detected in some" 6 "ovarian cancer: 18.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "U-266/70: 1.6;U-266/84: 6.4" HPA055955 Uncertain "Secreted in other tissues" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 44: Endometrium - Transcription" "HPA055955: AB_2682985" "unprognostic (2.30e-1)" "unprognostic (3.68e-1)" "unprognostic (4.63e-1)" "unprognostic (1.66e-2)" "unprognostic (2.17e-1)" "unprognostic (3.20e-1)" "unprognostic (2.75e-1)" "unprognostic (7.65e-2)" "unprognostic (2.23e-2)" "unprognostic (8.27e-2)" "unprognostic (1.91e-1)" "unprognostic (6.83e-11)" "unprognostic (5.17e-2)" "unprognostic (3.61e-1)" "unprognostic (1.26e-1)" "unprognostic (3.84e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.9 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.5 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 OBP2B "hOBPIIb, LCN14" ENSG00000171102 "Odorant binding protein 2B" Q9NPH6 9 133205277-133209250 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 2.7;testis: 10.0" "Group enriched" "Detected in some" 9 "Breast glandular cells: 17.7;Breast myoepithelial cells: 29.1" "Group enriched" "Detected in many" 8 "breast cancer: 7.8;endometrial cancer: 16.2;ovarian cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.40e-1)" "unprognostic (5.70e-2)" "unprognostic (9.45e-3)" "unprognostic (6.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (7.03e-2)" "unprognostic (6.82e-6)" "unprognostic (2.00e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.3 0.0 0.0 0.0 17.7 29.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 2.5 1.2 0.1 1.8 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.1 OC90 PLA2L ENSG00000253117 "Otoconin 90" Q02509 8 132024216-132059382 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.92e-1)" "unprognostic (2.93e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ODAPH "AI2A4, C4orf26, FLJ23657" ENSG00000174792 "Odontogenesis associated phosphoprotein" Q17RF5 4 75556048-75565871 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.7;placenta: 5.8" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 9.2;Syncytiotrophoblasts: 27.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.1;urothelial cancer: 0.7" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 33 "basophil: 10.7" "Lineage enriched" "Detected in single" 33 "granulocytes: 10.7" "Cell line enriched" "Detected in some" 6 "HDLM-2: 61.3" "Secreted in other tissues" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.13e-1)" "unprognostic (4.45e-3)" "unprognostic (3.78e-1)" "unprognostic (1.66e-1)" "unprognostic (6.12e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (2.44e-1)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.43e-1)" "unprognostic (1.17e-7)" "unprognostic (8.31e-2)" "unprognostic (2.70e-2)" "unprognostic (8.40e-4)" "unprognostic (6.53e-3)" 0.1 0.1 0.7 0.2 0.7 0.3 0.1 0.9 1.7 0.1 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.6 0.1 0.1 0.1 0.2 0.8 0.8 0.1 0.0 0.0 0.4 5.8 0.9 0.1 0.2 0.5 0.1 0.1 0.9 0.3 0.2 0.0 0.6 0.1 0.1 0.4 0.7 0.1 0.0 0.0 0.3 0.1 0.1 1.5 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 1.3 0.5 0.1 0.2 0.0 0.1 0.1 0.0 0.2 0.3 61.3 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.7 0.1 0.0 0.1 0.0 2.8 0.0 2.1 0.3 0.1 0.0 0.1 2.6 0.1 0.9 9.6 0.1 0.1 0.6 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.7 0.7 0.9 1.7 0.6 0.6 0.8 0.8 0.9 0.6 0.7 1.5 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 1.8 0.0 1.9 0.1 0.0 0.0 3.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 9.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 27.0 0.1 0.1 0.0 0.0 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 OIT3 "FLJ39116, LZP" ENSG00000138315 "Oncoprotein induced transcript 3" Q8WWZ8 10 72893584-72933036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 110.8" "Cell type enriched" "Detected in some" 11 "Hepatic stellate cells: 372.3" "Cancer enriched" "Detected in many" 4 "liver cancer: 4.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 2.3;Hep G2: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 52000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.42e-2)" "unprognostic (6.76e-2)" "unprognostic (7.98e-4)" "unprognostic (9.26e-2)" "unprognostic (9.47e-4)" "unprognostic (3.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.99e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.50e-3)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" "unprognostic (1.35e-1)" "unprognostic (2.44e-1)" "unprognostic (3.68e-3)" "unprognostic (1.19e-1)" 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.3 0.5 0.0 0.1 0.3 5.3 0.0 0.0 0.0 0.0 0.3 2.8 0.1 0.0 1.5 110.8 0.3 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 6.1 0.0 0.0 7.8 0.1 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.3 0.5 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 10.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 14.6 0.0 10.7 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 372.3 10.6 0.0 0.0 0.9 0.0 0.0 31.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.4 0.5 0.0 0.0 OLFM1 "AMY, NOE1, NOELIN, OlfA" ENSG00000130558 "Olfactomedin 1" Q99784 9 135075422-135121180 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 555.7;choroid plexus: 246.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.1;Hepatic stellate cells: 78.1;Inhibitory neurons: 70.0" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;intermediate monocyte: 2.8;myeloid DC: 2.6" "Group enriched" "Detected in many" 27 "dendritic cells: 2.6;monocytes: 2.8" "Cell line enhanced" "Detected in many" "HeLa: 96.0;MCF7: 84.1;NTERA-2: 104.9;OE19: 78.9;SCLC-21H: 155.6;SiHa: 131.8;T-47d: 200.2;U-2197: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057444 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in brain" NA NA 200000000 "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Cytosol" "HPA057444: AB_2683443" "unprognostic (6.77e-2)" "prognostic favorable (7.14e-4)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.69e-3)" "unprognostic (2.67e-1)" "unprognostic (6.04e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (9.46e-3)" "unprognostic (4.60e-2)" "unprognostic (1.51e-1)" "unprognostic (6.20e-2)" "unprognostic (7.53e-4)" 36.7 25.4 410.4 13.0 427.0 0.2 36.8 309.6 555.7 29.9 246.9 24.0 5.0 29.0 70.4 12.1 30.3 8.6 20.7 474.7 309.0 20.3 4.8 15.0 14.5 296.6 301.7 19.4 12.3 4.9 82.8 1.0 293.9 19.3 13.8 47.3 14.0 18.1 17.5 15.3 16.5 17.9 279.9 35.1 15.4 6.8 317.0 11.5 17.5 23.0 19.1 25.0 26.7 372.3 0.0 6.1 12.1 0.2 1.7 1.4 0.5 3.6 0.0 0.0 0.0 0.1 2.7 0.1 0.8 5.2 49.2 2.3 2.6 0.0 0.0 14.4 0.9 0.2 96.0 0.0 0.5 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.3 84.1 0.5 0.3 104.9 78.9 0.0 0.1 0.3 48.3 0.0 0.1 155.6 20.5 131.8 0.4 8.6 7.9 200.2 0.0 0.1 7.7 16.6 87.1 0.2 0.2 0.1 0.3 0.7 0.1 4.3 0.0 1.8 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 410.4 427.0 309.6 555.7 474.7 309.0 296.6 301.7 293.9 279.9 317.0 372.3 44.2 0.0 7.9 43.8 0.1 9.7 3.3 0.0 3.4 21.6 3.1 3.0 5.9 11.5 1.8 0.0 43.8 0.0 0.1 2.4 0.0 9.7 5.8 0.5 20.4 50.0 2.4 0.0 193.1 2.7 0.0 17.3 0.0 0.7 2.5 14.4 78.1 1.1 0.4 38.7 70.0 2.5 0.0 3.2 7.3 11.9 44.4 2.8 21.4 32.8 2.7 38.6 0.0 48.7 17.3 2.5 2.5 29.3 0.4 5.1 0.0 0.1 0.0 15.7 0.0 13.3 8.8 0.6 3.7 1.3 6.3 0.0 0.7 12.9 4.2 1.4 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 OLFM3 NOE3 ENSG00000118733 "Olfactomedin 3" Q96PB7 1 101802560-101996926 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 12.0;retina: 7.4" "Group enriched" "Detected in some" 17 "Excitatory neurons: 653.3;Inhibitory neurons: 174.6" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AF22: 5.7;HAP1: 3.9;HEL: 3.6;SCLC-21H: 2.2;SH-SY5Y: 2.2" "Region enhanced" "Detected in all" "cerebellum: 177.3" "Low region specificity" "Detected in all" HPA050297 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA050297: " "unprognostic (4.19e-1)" "unprognostic (4.19e-4)" "unprognostic (1.26e-1)" "unprognostic (4.61e-2)" "unprognostic (2.93e-1)" "unprognostic (1.47e-2)" "unprognostic (3.58e-4)" "unprognostic (2.48e-1)" "unprognostic (5.68e-2)" 0.0 1.3 2.9 0.3 5.0 0.0 0.0 6.9 12.0 0.0 0.0 0.6 0.2 0.1 0.2 0.0 0.0 0.0 0.0 6.4 3.9 0.4 0.0 0.0 0.0 1.2 1.9 0.0 0.0 0.0 1.2 0.0 1.2 0.0 0.5 7.4 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.2 0.1 3.7 0.0 0.3 0.0 0.0 0.0 0.0 4.6 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 2.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 5.0 6.9 12.0 6.4 3.9 1.2 1.9 1.2 0.0 3.7 4.6 0.1 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 23.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 653.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 174.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.7 0.0 8.5 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 6.5 0.0 0.0 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 40.1;Endothelial cells: 21.2;Fibroblasts: 29.0;Skeletal myocytes: 63.0;Smooth muscle cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 160.0;GAMG: 34.0;HeLa: 39.8;hTERT-RPE1: 38.0;WM-115: 64.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 240000 "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA021180: AB_1854790, HPA022254: AB_1854791" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-1)" "unprognostic (4.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.26e-3)" "unprognostic (7.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (5.72e-3)" "unprognostic (3.30e-2)" "unprognostic (7.91e-2)" "unprognostic (1.05e-2)" 15.4 2.9 2.6 2.7 3.1 0.3 11.1 2.2 4.6 25.0 3.3 29.9 3.3 25.3 2.8 8.2 6.4 4.8 16.4 2.2 2.4 4.3 0.7 10.5 2.4 2.8 2.1 12.0 4.8 4.6 2.8 7.0 2.8 7.4 6.2 2.2 7.0 12.2 10.8 16.0 6.9 16.0 2.1 32.8 5.5 1.1 2.6 3.1 19.1 10.0 3.7 17.6 14.6 2.1 0.8 14.6 1.2 0.4 16.8 160.0 0.1 1.8 8.2 3.5 3.5 0.2 2.2 0.0 3.4 0.1 34.0 25.5 0.4 0.8 4.0 0.0 0.1 0.0 39.8 0.1 0.9 0.0 0.1 11.3 2.7 10.2 1.4 38.0 0.0 0.0 0.0 0.2 1.8 0.4 0.0 0.3 3.4 0.0 0.9 0.0 9.5 0.0 0.0 1.2 0.0 0.1 2.9 0.2 4.3 28.6 3.9 0.5 0.1 5.2 4.6 5.5 0.7 1.9 0.0 0.1 15.2 0.8 64.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 2.6 3.1 2.2 4.6 2.2 2.4 2.8 2.1 2.8 2.1 2.6 2.1 40.1 0.0 1.3 0.7 0.4 12.0 5.9 17.5 6.2 0.6 2.9 8.3 13.8 1.5 5.5 0.0 2.1 0.3 0.5 0.0 0.0 0.1 0.7 0.2 1.5 21.2 0.0 0.0 0.4 0.6 0.3 29.0 0.5 0.2 0.0 0.9 3.6 0.1 0.1 0.0 0.6 0.0 4.1 1.5 7.9 1.4 2.8 0.9 10.6 8.4 0.1 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.1 4.0 0.0 0.1 11.5 4.0 13.1 63.0 36.4 0.4 0.7 4.5 8.4 0.0 0.6 4.2 0.0 3.5 OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.3" "Cell type enhanced" "Detected in many" "Early spermatids: 122.5;Hofbauer cells: 38.4;Skeletal myocytes: 175.5;Smooth muscle cells: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.7;HSkMC: 113.3;RH-30: 88.5" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA054136: AB_2682397, HPA062739: AB_2684858" "unprognostic (2.97e-2)" "unprognostic (1.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (5.97e-3)" "unprognostic (7.32e-2)" "unprognostic (7.68e-3)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.01e-12)" "unprognostic (1.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.53e-3)" "unprognostic (1.97e-2)" 23.4 6.9 4.2 19.2 7.5 0.4 14.7 2.4 5.6 16.8 6.0 18.3 2.1 16.2 5.0 3.9 11.4 48.3 6.6 5.7 3.4 3.1 0.8 15.3 14.0 3.7 4.0 4.2 1.4 3.5 2.8 40.6 4.7 5.3 2.9 0.2 10.4 6.9 10.2 10.1 5.5 22.0 3.0 10.2 3.3 15.9 9.8 3.7 20.8 6.5 11.2 16.8 7.3 4.2 0.1 0.4 6.6 2.2 21.0 39.7 0.0 2.3 10.6 4.3 11.8 0.0 0.2 0.0 0.3 25.7 4.3 0.0 0.6 0.1 2.5 0.0 0.8 0.5 0.2 0.0 0.3 0.1 0.8 113.3 0.0 5.3 0.0 2.1 0.7 0.0 0.0 1.0 19.3 0.1 0.1 0.2 2.1 0.0 1.0 0.2 88.5 8.9 1.6 0.1 0.8 0.3 9.1 0.0 0.6 19.6 0.0 0.1 0.1 2.7 0.7 4.0 3.6 0.0 0.1 0.0 25.1 2.7 1.3 0.0 0.4 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.2 4.2 7.5 2.4 5.6 5.7 3.4 3.7 4.0 4.7 3.0 9.8 4.2 4.1 0.0 0.6 0.0 0.2 3.3 0.1 0.1 0.0 0.1 0.4 1.0 3.0 1.5 0.7 1.8 0.0 0.3 0.1 0.0 0.0 0.0 122.5 1.2 24.9 1.7 0.0 0.4 2.8 0.0 0.3 21.9 0.0 0.7 1.3 1.1 1.1 0.2 38.4 0.0 0.9 0.1 0.0 31.1 9.0 12.9 20.8 16.6 1.8 8.4 0.9 0.8 0.0 0.0 2.9 0.0 0.0 29.3 0.1 0.1 0.0 0.1 0.1 0.1 6.6 175.5 57.2 8.8 1.7 0.1 2.3 0.3 0.6 16.4 0.0 0.0 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OOSP2 "FLJ36198, OOSP2A, PLAC1L, TMEM122" ENSG00000149507 "Oocyte secreted protein 2" Q86WS3 11 60040409-60048044 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 180 "testis: 18.0" "Cell type enriched" "Detected in some" 5 "Late spermatids: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA050914 Enhanced "Secreted in male reproductive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA050914: AB_2681271" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OOSP3 ENSG00000285231 "Oocyte secreted protein family member 3" A0A2R8YFM6 11 59878809-59896481 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "basophil: 5.5" "Lineage enriched" "Detected in single" 55 "granulocytes: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 41: Basophils - Cellular respiration" 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OOSP4A ENSG00000285010 "Oocyte secreted protein family member 4A" A0A2R8YFL7 11 59964033-59970146 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "basophil: 4.1" "Lineage enriched" "Detected in single" 12 "granulocytes: 4.1" "Group enriched" "Detected in some" 5 "HEL: 1.0;K-562: 2.6" "Secreted - unknown location" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 1: K-562 - Erythropoiesis" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.2 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OOSP4B ENSG00000255393 "Oocyte secreted protein family member 4B" A0A2R8Y4Y8 11 59978020-60031077 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPRPN "BPLP, PRL1, PROL1" ENSG00000171199 "Opiorphin prepropeptide" Q99935 4 70397931-70410195 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 146.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.5;Breast myoepithelial cells: 3.3;Glandular and luminal cells: 2.1" "Group enriched" "Detected in some" 5 "breast cancer: 7.4;liver cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA065711 Approved "Secreted in other tissues" NA NA 63000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: Glandular cells - Unknown function" "HPA065711: AB_2685541" "unprognostic (3.11e-3)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 146.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 OPTC ENSG00000188770 Opticin Q9UBM4 1 203494153-203508949 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 1.5;Spermatocytes: 1.5" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034951, HPA034952" Enhanced "Secreted in other tissues" NA NA "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA034951: AB_10669852, HPA034952: AB_2674379" "unprognostic (3.29e-1)" "unprognostic (1.56e-1)" "unprognostic (7.69e-2)" "unprognostic (3.19e-2)" "unprognostic (1.70e-3)" "unprognostic (8.24e-2)" "unprognostic (3.65e-2)" 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.4 0.3 0.1 0.1 0.2 0.0 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.5 0.6 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.4 0.3 0.2 0.5 0.8 0.7 0.8 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ORM1 ENSG00000229314 "Orosomucoid 1" P02763 9 114323056-114326475 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 193 "liver: 42973.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 58657.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 2506.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 47 "neutrophil: 193.9" "Lineage enriched" "Detected in many" 47 "granulocytes: 193.9" "Cell line enriched" "Detected in some" 12 "Hep G2: 1182.7" "CAB006265, HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 945000000000 61000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Golgi apparatus" "CAB006265: AB_425575, HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (3.85e-1)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (1.16e-1)" "unprognostic (4.85e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.35e-4)" "unprognostic (2.10e-1)" "unprognostic (4.38e-2)" "unprognostic (9.32e-3)" "unprognostic (4.51e-2)" 13.4 10.3 0.1 12.7 0.3 223.1 6.6 0.0 0.4 2.7 0.2 1.5 0.1 2.7 0.3 1.9 1.9 1.0 3.4 0.2 0.2 4.9 42973.6 24.4 0.7 0.4 0.2 1.6 8.1 0.0 1.4 1.3 0.1 57.6 0.0 1.1 1.4 0.0 2.0 1.7 2.3 0.3 0.2 51.3 19.2 2.7 0.1 1.2 2.8 0.3 0.1 1.6 2.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 2.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 3.4 0.6 1182.7 0.1 5.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.2 0.0 0.2 1.0 0.1 0.0 0.7 7.1 0.0 0.0 0.4 0.0 0.0 5.7 5.5 0.0 0.0 0.4 102.0 1.2 0.0 0.5 0.0 0.0 1.2 0.6 3.5 0.0 4.3 0.1 0.0 4.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.9 0.0 1.0 0.0 0.0 1.8 0.1 0.3 0.0 0.4 0.2 0.2 0.4 0.2 0.1 0.2 0.1 0.2 0.0 3.2 18.1 0.0 81.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1166.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 1.3 0.2 34.4 0.0 890.4 0.0 4.9 0.3 0.2 0.0 2.5 0.0 0.0 930.9 58657.7 0.1 0.0 0.0 0.0 0.0 1260.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.0 0.3 ORM2 "AGP-B, AGP-B', AGP2" ENSG00000228278 "Orosomucoid 2" P19652 9 114329869-114333251 "Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 327 "liver: 8873.2" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 10792.5" "Cancer enriched" "Detected in many" 34 "liver cancer: 873.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 40 "neutrophil: 12.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 12.0" "Cell line enriched" "Detected in some" 232 "Hep G2: 831.1" "HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 422000000 41000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus" "HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (6.77e-2)" "unprognostic (8.00e-2)" "unprognostic (1.19e-1)" "unprognostic (4.44e-3)" "unprognostic (1.18e-1)" "unprognostic (5.61e-2)" "unprognostic (5.66e-2)" "unprognostic (9.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (1.23e-9)" "unprognostic (3.23e-1)" "unprognostic (6.80e-2)" "unprognostic (7.62e-2)" "unprognostic (9.15e-4)" 4.0 4.0 0.2 3.2 0.4 27.1 3.0 0.0 0.2 1.3 0.2 0.3 0.2 2.1 0.1 0.4 0.4 0.6 0.8 0.1 0.1 1.7 8873.2 5.8 1.1 0.2 0.3 0.3 2.1 0.0 0.2 0.2 0.1 23.6 0.1 3.6 0.3 0.0 0.4 0.4 0.4 0.1 0.2 7.3 21.9 1.4 0.1 0.5 0.3 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 831.1 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.2 0.0 0.0 0.1 1.1 0.4 2.5 0.0 0.3 1.9 0.1 0.0 0.3 0.1 0.0 2.6 2.0 0.2 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.7 0.6 2.2 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 0.3 0.1 0.2 0.1 0.2 0.0 0.0 10.5 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 263.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 6.6 1.1 0.1 7.0 0.0 141.7 0.0 6.0 0.0 0.0 15.8 1.3 0.0 0.0 162.8 10792.5 0.0 0.0 0.0 0.0 0.0 236.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.2 OSM MGC20461 ENSG00000099985 "Oncostatin M" P13725 22 30262829-30266851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Cytokine, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 118.2" "Group enriched" "Detected in some" 4 "Hofbauer cells: 74.4;Macrophages: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 65.2;neutrophil: 34.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "HDLM-2: 15.7;HL-60: 3.8;HMC-1: 11.1;Karpas-707: 3.5;NB-4: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 39700 "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.15e-2)" "unprognostic (8.80e-3)" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (7.37e-2)" "unprognostic (2.61e-2)" "unprognostic (6.78e-2)" "unprognostic (3.77e-2)" "unprognostic (2.81e-2)" "unprognostic (4.60e-2)" "unprognostic (1.58e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.00e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.82e-1)" 7.2 3.6 0.8 14.3 1.0 118.2 0.8 0.8 4.2 1.2 2.0 1.0 0.5 1.1 0.1 0.8 2.3 6.2 1.4 0.6 1.5 2.0 1.9 7.8 1.6 1.8 0.9 0.5 1.2 0.9 1.5 5.5 1.7 1.0 0.5 0.1 1.1 0.2 0.2 0.2 0.7 3.1 1.6 5.0 0.9 0.4 4.7 2.6 0.8 2.9 0.8 12.7 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.7 0.0 0.3 0.0 0.0 0.0 3.8 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 3.5 0.0 0.0 0.5 6.6 0.0 0.0 0.0 0.6 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.3 0.0 65.2 0.5 2.0 2.0 0.3 6.5 0.0 4.8 2.6 0.8 0.2 0.9 2.4 34.9 4.3 0.1 0.2 1.4 1.6 0.8 1.0 0.8 4.2 0.6 1.5 1.8 0.9 1.7 1.6 4.7 2.9 0.9 9.6 10.6 0.0 3.2 0.8 0.2 0.0 0.0 0.0 0.7 1.8 0.6 0.0 3.7 0.0 0.0 0.8 13.2 0.0 0.0 0.1 0.1 0.6 0.2 1.9 0.0 1.3 0.1 0.0 0.9 1.4 0.0 1.1 15.2 0.0 0.4 0.0 74.4 0.0 0.1 0.1 0.0 6.1 12.4 0.0 0.0 51.6 0.0 0.0 1.8 0.1 1.0 0.0 0.1 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.7 0.2 0.0 0.7 0.4 0.0 0.0 0.3 0.3 0.8 14.2 0.1 0.0 0.0 OSTN ENSG00000188729 Osteocrin P61366 3 191199241-191265615 "Predicted secreted proteins" Differentiation "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Early spermatids: 4.2;Excitatory neurons: 1.0;Inhibitory neurons: 5.9;Late spermatids: 1.4;Oligodendrocyte precursor cells: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6 "memory B-cell: 4.0;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 9 "B-cells: 4.0" "Cell line enriched" "Detected in some" 24 "U-2197: 39.1" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in single" "CAB024997, CAB025649, HPA030878" Uncertain "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB024997: , CAB025649: , HPA030878: AB_2673642" "unprognostic (2.35e-2)" "unprognostic (9.12e-2)" "unprognostic (6.30e-2)" "unprognostic (2.34e-1)" "unprognostic (2.51e-1)" "unprognostic (3.01e-2)" "unprognostic (2.52e-1)" "unprognostic (8.11e-3)" "unprognostic (2.90e-1)" "unprognostic (1.45e-1)" 0.3 0.1 0.6 0.7 0.9 0.0 0.1 0.1 1.2 1.2 0.2 0.1 0.0 0.1 1.6 0.0 0.7 0.8 0.4 0.8 0.8 0.1 0.6 0.2 0.6 0.5 0.2 0.2 0.0 0.0 0.0 0.4 0.5 0.6 0.0 0.1 0.2 0.1 0.8 1.2 0.1 0.0 0.4 0.2 0.3 0.4 0.3 0.1 0.1 1.0 0.0 1.3 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.1 0.0 1.6 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.9 0.1 1.2 0.8 0.8 0.5 0.2 0.5 0.4 0.3 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 5.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OTOA "CT108, DFNB22" ENSG00000155719 Otoancorin Q7RTW8 16 21663968-21761935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 1.8;testis: 4.0" "Cell type enhanced" "Detected in some" "Hofbauer cells: 111.8;Kupffer cells: 60.5;Late spermatids: 18.7;Macrophages: 34.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041405 Enhanced "Secreted in other tissues" NA NA 51000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Macrophages - Innate immune response" "HPA041405: AB_10796344" "unprognostic (7.96e-2)" "unprognostic (2.44e-4)" "unprognostic (1.66e-2)" "unprognostic (9.69e-2)" "unprognostic (2.15e-1)" "unprognostic (1.35e-1)" "unprognostic (5.11e-1)" "unprognostic (4.71e-2)" "unprognostic (7.92e-2)" "unprognostic (3.58e-1)" "unprognostic (1.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.08e-4)" "unprognostic (1.83e-1)" "unprognostic (1.20e-1)" "unprognostic (2.24e-1)" "unprognostic (2.18e-2)" 0.1 0.2 0.2 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 4.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.3 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 8.4 0.0 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.0 1.8 0.0 0.4 0.1 0.3 0.0 0.2 11.6 0.3 0.2 1.0 1.2 0.0 2.6 0.4 0.8 0.3 0.0 0.5 5.7 0.1 0.7 0.4 111.8 0.0 1.8 0.1 0.0 60.5 3.7 18.7 0.3 34.4 1.8 0.0 1.9 0.0 0.0 0.5 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.7 0.0 0.0 6.6 0.2 0.7 9.4 7.4 0.0 0.1 0.5 0.2 0.1 0.2 0.2 OTOG "FLJ46346, mlemp, OTGN" ENSG00000188162 Otogelin Q6ZRI0 11 17547259-17647150 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pituitary gland: 1.4" "Group enriched" "Detected in some" 5 "Early spermatids: 11.9;Late spermatids: 28.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "CACO-2: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.25e-2)" "unprognostic (1.19e-1)" "unprognostic (6.95e-3)" "unprognostic (1.85e-6)" "unprognostic (1.89e-1)" "unprognostic (3.60e-1)" "unprognostic (5.14e-5)" "unprognostic (1.78e-1)" "unprognostic (8.97e-2)" "unprognostic (1.57e-2)" "unprognostic (4.72e-5)" "unprognostic (5.55e-2)" "unprognostic (1.48e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 OTOGL "C12orf64, FLJ90579" ENSG00000165899 "Otogelin like" Q3ZCN5 12 80099537-80380880 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.9;kidney: 5.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 51.2;Oligodendrocyte precursor cells: 42.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.3;U-87 MG: 2.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "basal ganglia: 4.2" "HPA040364, HPA053392" Uncertain Approved Cytosol "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA040364: AB_10795365, HPA053392: AB_2682135" "unprognostic (2.43e-1)" "unprognostic (2.78e-2)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" "unprognostic (5.99e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-3)" "unprognostic (4.76e-2)" "unprognostic (2.72e-2)" "unprognostic (4.52e-2)" "unprognostic (2.79e-2)" "unprognostic (1.57e-1)" "unprognostic (1.95e-5)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.79e-2)" "unprognostic (2.04e-2)" 0.1 0.0 0.5 0.0 0.7 0.0 0.1 0.0 1.0 0.1 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.1 1.9 0.3 0.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.5 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.3 0.0 0.0 2.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.4 0.1 0.1 0.2 0.0 0.0 51.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.0 0.0 0.0 42.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 OTOL1 "C1QTNF15, C1QTNF16" ENSG00000182447 "Otolin 1" A6NHN0 3 161496808-161503942 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041030 Uncertain "Secreted in other tissues" NA NA "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA041030: AB_10795000" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 OTOR "FDP, MIAL, MIAL1" ENSG00000125879 Otoraplin Q9NRC9 20 16748358-16770062 "Predicted secreted proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA024335 Uncertain "Secreted in other tissues" NA NA "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA024335: AB_1854838" "unprognostic (8.50e-3)" "unprognostic (9.56e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-1)" "unprognostic (1.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 12.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OTOS OTOSP ENSG00000178602 Otospiralin Q8NHW6 2 240139026-240144562 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 103.1;thyroid gland: 43.8" "Cell type enhanced" "Detected in single" "Astrocytes: 1.3" "Cancer enriched" "Detected in some" 4 "thyroid cancer: 28.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (8.52e-2)" "unprognostic (1.73e-1)" "unprognostic (9.01e-3)" "unprognostic (1.35e-1)" "unprognostic (2.72e-1)" "unprognostic (3.27e-3)" 0.0 0.0 10.9 0.0 11.0 0.0 0.1 11.3 11.5 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 14.2 0.3 0.2 0.0 0.0 10.5 11.7 0.0 0.0 0.0 103.1 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 12.7 0.0 43.8 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 11.0 11.3 11.5 11.7 14.2 10.5 11.7 11.2 9.7 12.7 12.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OVCH1 OVCH ENSG00000187950 "Ovochymase 1" Q7RTY7 12 29412474-29497686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 4.5;testis: 2.4" "Group enriched" "Detected in some" 5 "Excitatory neurons: 14.3;Inhibitory neurons: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Daudi: 5.5" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.32e-1)" "unprognostic (2.20e-1)" "unprognostic (2.03e-1)" "unprognostic (1.56e-5)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.36e-1)" "unprognostic (5.48e-2)" "unprognostic (5.59e-3)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" 0.2 0.2 0.7 0.3 1.2 0.1 0.2 0.0 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.9 0.5 0.1 0.2 4.5 0.1 0.0 0.6 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.6 0.1 2.4 0.7 0.0 1.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 1.2 0.9 0.5 0.0 0.6 0.1 0.1 0.7 0.5 0.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.1 0.7 0.0 0.0 14.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OVCH2 OVTN ENSG00000183378 "Ovochymase 2" 11 7689437-7706421 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 15 "epididymis: 189.0;retina: 92.2" "Group enriched" "Detected in some" 7 "Collecting duct cells: 7.3;Rod photoreceptor cells: 16.6" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "REH: 25.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.59e-2)" "unprognostic (3.74e-1)" "unprognostic (8.03e-2)" "unprognostic (9.77e-2)" "unprognostic (1.85e-1)" "unprognostic (1.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.84e-2)" "unprognostic (3.06e-1)" "unprognostic (9.27e-2)" "unprognostic (7.65e-2)" "unprognostic (1.22e-2)" 0.0 0.0 0.1 0.0 0.3 0.4 3.4 0.8 0.2 0.1 0.1 0.0 0.0 0.2 189.0 0.1 0.3 0.0 0.0 0.0 0.1 5.3 0.0 2.4 0.0 0.7 0.4 0.0 0.0 0.0 0.0 1.4 1.0 1.1 0.0 92.2 0.8 5.8 0.4 9.1 0.1 0.0 0.1 0.0 0.5 0.5 0.8 0.0 0.0 0.0 0.1 0.9 0.2 0.7 3.4 0.0 0.3 0.0 0.0 0.0 0.5 0.8 0.6 0.1 0.3 0.2 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 25.2 0.0 0.2 0.2 2.7 0.0 0.2 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.2 0.0 0.1 0.7 0.4 1.0 0.1 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.1 1.3 0.1 0.0 0.0 7.3 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.7 0.0 0.1 0.0 0.7 0.0 16.6 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 OVGP1 "CHIT5, MUC9" ENSG00000085465 "Oviductal glycoprotein 1" Q12889 1 111414319-111427735 "Plasma proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 134 "fallopian tube: 2071.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 9.7;Excitatory neurons: 10.4;Glandular and luminal cells: 12.0;Inhibitory neurons: 8.5;Syncytiotrophoblasts: 17.4" "Group enriched" "Detected in many" 13 "endometrial cancer: 58.7;ovarian cancer: 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 4.9;OE19: 6.4;SK-BR-3: 5.0" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Not detected" "Not detected" "HPA031666, HPA062205" Enhanced Supported Vesicles,Microtubules "Secreted in female reproductive system" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Microtubules "HPA031666: , HPA062205: AB_2684710" "unprognostic (1.52e-1)" "unprognostic (2.06e-2)" "unprognostic (3.35e-2)" "prognostic favorable (1.36e-4)" "unprognostic (8.39e-2)" "unprognostic (3.58e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-2)" "unprognostic (5.44e-2)" "unprognostic (3.82e-2)" "unprognostic (7.68e-3)" "unprognostic (2.58e-1)" "unprognostic (5.35e-3)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-3)" "prognostic favorable (3.93e-5)" 4.1 1.6 7.6 1.1 7.8 1.9 3.5 8.0 10.6 3.8 5.8 3.4 1.1 15.4 5.1 3.0 2071.7 1.1 2.3 7.7 7.0 5.0 8.0 3.9 2.2 7.3 6.9 6.7 1.5 6.8 2.4 2.0 7.2 5.5 2.2 4.3 4.2 1.5 2.6 7.6 5.2 1.4 6.5 4.6 2.8 9.2 6.9 1.2 2.4 1.0 2.0 4.6 3.8 8.2 0.4 0.4 0.9 0.5 1.8 2.0 1.7 0.2 1.4 0.3 0.7 0.6 0.0 0.8 1.7 0.6 0.0 0.5 0.3 0.3 0.5 2.0 4.9 0.3 0.8 2.4 0.6 0.9 2.2 1.8 2.9 0.0 1.0 1.4 0.4 3.2 0.3 1.5 0.1 0.5 0.6 1.2 0.2 6.4 1.7 0.6 0.2 0.7 1.4 3.7 0.6 0.6 0.1 5.0 0.7 2.4 0.3 0.8 0.8 0.1 0.2 2.5 0.7 1.8 0.5 0.4 0.2 1.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 7.8 8.0 10.6 7.7 7.0 7.3 6.9 7.2 6.5 6.9 8.2 1.2 0.0 1.1 3.3 0.6 3.1 1.1 0.3 0.0 2.1 1.7 1.9 0.6 0.0 0.5 0.0 0.0 5.6 0.2 1.1 1.9 0.2 4.0 9.7 0.7 1.6 0.0 0.0 10.4 0.0 2.6 0.6 0.0 12.0 0.0 1.0 1.4 2.9 0.6 0.0 8.5 1.5 2.0 0.6 1.4 6.1 1.5 0.5 0.0 3.7 0.0 0.4 0.0 1.5 2.4 0.2 0.5 1.9 0.1 1.6 0.6 2.8 1.3 0.6 0.0 0.7 1.1 3.8 0.7 1.0 3.1 17.4 0.8 0.2 1.6 1.6 OXT "OT, OT-NPI, OXT-NPI" ENSG00000101405 "Oxytocin/neurophysin I prepropeptide" P01178 20 3071620-3072517 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "brain: 1167.9" "Cell type enhanced" "Detected in many" "Early spermatids: 30.0;Hepatocytes: 41.2;Late spermatids: 66.3;Proximal enterocytes: 15.7;Proximal tubular cells: 36.5" "Cancer enriched" "Detected in some" 5 "testis cancer: 12.1" "Region enriched" "Detected in many" 141 "hypothalamus: 1167.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;HMC-1: 1.1" "Region enriched" "Detected in many" 6 "hypothalamus: 179.3" "Group enriched" "Detected in some" 903 "basal ganglia: 794.6;hypothalamus: 1854.1" HPA071892 Supported Supported "Secreted to blood" NA NA 1500000 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA071892: AB_2732190" "unprognostic (7.45e-3)" "unprognostic (1.99e-2)" "unprognostic (2.66e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-1)" "unprognostic (3.82e-2)" "unprognostic (8.22e-2)" "unprognostic (8.36e-2)" "unprognostic (6.02e-2)" "unprognostic (3.05e-2)" "unprognostic (6.65e-2)" "unprognostic (6.18e-1)" "unprognostic (3.81e-1)" "unprognostic (3.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" 3.2 1.7 8.3 0.0 0.8 0.1 1.7 0.5 0.9 0.9 0.7 0.4 1.0 0.4 0.0 0.2 0.3 0.0 0.5 0.2 1167.9 4.1 19.3 0.2 0.1 0.2 0.7 0.3 0.1 0.0 15.9 0.0 0.2 0.7 0.0 0.0 0.5 0.1 0.2 2.3 1.0 0.0 1.3 0.2 0.2 2.6 7.8 0.0 0.6 0.0 0.0 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.4 0.4 0.2 0.5 2.1 0.8 0.5 0.4 1.6 1.4 1.7 0.5 0.2 0.0 0.7 1.3 0.3 8.3 0.8 0.5 0.9 0.2 1167.9 0.2 0.7 0.2 1.3 7.8 0.2 0.6 0.0 1.8 0.3 3.5 0.8 0.7 0.1 1.2 0.0 1.2 1.7 0.2 0.0 1.3 5.5 0.0 0.0 2.3 0.1 1.9 0.1 30.0 0.2 2.4 0.3 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.5 0.0 0.3 0.0 41.2 0.2 0.0 0.1 1.8 0.0 0.3 1.6 66.3 0.9 0.6 3.6 0.0 0.0 0.0 1.0 0.5 0.0 0.2 1.7 1.2 1.2 0.4 15.7 36.5 0.9 0.0 0.0 1.8 0.7 1.1 7.8 0.3 1.0 0.0 1.1 0.0 2.0 0.3 PAEP "GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14" ENSG00000122133 "Progestagen associated endometrial protein" P09466 9 135561756-135566955 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 94.1;endometrium 1: 256.0" "Cell type enriched" "Detected in some" 10 "Glandular and luminal cells: 10785.5" "Cancer enriched" "Detected in many" 8 "melanoma: 275.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.1;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016762, HPA020108, HPA029473" Enhanced "Secreted in female reproductive system" NA NA 120000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "CAB016762: , HPA020108: AB_1855595, HPA029473: AB_10610147" "unprognostic (3.39e-2)" "unprognostic (8.47e-3)" "unprognostic (6.84e-2)" "unprognostic (3.46e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (1.27e-2)" "unprognostic (1.72e-1)" "unprognostic (3.95e-3)" "unprognostic (1.93e-3)" "prognostic unfavorable (0.00e+0)" "prognostic unfavorable (5.46e-4)" "unprognostic (4.24e-1)" "unprognostic (4.98e-2)" 0.1 0.2 0.2 1.1 0.4 1.6 0.5 0.7 0.7 94.1 2.0 0.1 1.0 256.0 0.9 0.2 4.8 0.3 0.1 0.4 0.4 0.1 0.1 0.5 0.6 0.3 0.2 0.7 0.0 0.0 0.0 27.2 0.2 2.7 0.1 0.4 0.4 44.8 0.6 2.1 0.8 0.1 0.1 0.3 6.0 0.7 0.4 0.0 0.3 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.0 0.9 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.6 1.6 2.2 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.2 2.9 0.2 0.0 0.3 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.3 0.0 0.2 0.4 0.2 0.1 0.2 21.0 0.6 0.3 0.2 0.0 0.0 1.0 0.2 0.1 0.8 2.2 0.1 0.2 0.2 0.2 3.1 0.3 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.1 0.4 0.3 0.3 1.4 0.3 0.3 0.5 0.1 0.1 0.2 0.4 0.7 0.7 0.4 0.4 0.3 0.2 0.2 0.1 0.4 1.0 0.0 0.0 0.5 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.9 0.6 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 613.5 1008.8 67.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 10785.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 144.0 0.0 0.0 0.0 0.0 0.0 86.5 0.0 0.0 0.0 PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103031105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1560.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1406.5;Enteroendocrine cells: 321.4;Inhibitory neurons: 487.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 529.9;fHDF/TERT166: 714.5;hTERT-RPE1: 562.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA 98000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: AB_2677919" "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" 119.3 202.5 71.6 34.6 81.4 10.1 99.0 50.7 82.5 595.0 96.2 125.1 52.6 140.9 678.2 69.4 87.6 97.3 1560.4 75.2 179.9 116.0 20.1 88.3 27.7 86.5 99.8 136.4 104.4 257.8 137.0 60.0 170.9 91.6 80.4 37.6 205.4 236.5 155.3 66.9 52.1 157.9 55.7 52.5 131.6 22.4 106.0 17.9 95.1 159.4 30.5 103.3 116.1 50.0 111.3 16.3 195.9 87.2 529.9 314.8 78.0 307.6 457.0 89.1 268.9 53.5 143.2 0.1 65.0 714.5 125.7 36.8 11.0 135.3 244.0 13.5 44.7 22.9 60.0 17.7 80.3 7.4 23.9 173.4 57.3 65.6 49.2 562.6 186.8 8.9 0.9 15.0 255.6 22.9 0.1 3.2 35.3 19.7 59.3 8.5 108.9 62.4 346.1 13.0 92.3 63.9 131.2 8.3 83.3 114.0 34.0 7.3 144.9 280.8 72.4 133.3 93.4 33.1 8.6 0.4 322.3 30.8 247.6 4.2 8.0 0.2 20.7 1.5 14.9 0.8 12.3 15.6 3.1 0.4 4.1 6.8 16.6 26.3 3.4 1.6 19.9 10.8 71.6 81.4 50.7 82.5 75.2 179.9 86.5 99.8 170.9 55.7 106.0 50.0 45.7 54.5 39.3 47.0 3.9 28.2 12.0 26.1 12.0 19.1 27.5 12.1 1406.5 0.0 30.4 60.7 2.1 1.6 12.6 13.7 7.9 12.6 8.8 47.6 48.6 63.5 321.4 3.4 229.2 21.5 40.6 220.4 26.0 83.0 9.5 68.3 74.6 3.5 5.9 8.4 487.7 13.8 18.3 10.3 48.3 8.1 60.3 9.3 37.4 192.0 9.5 11.6 22.6 154.8 9.3 30.6 6.3 58.6 12.1 26.4 4.8 43.8 19.2 3.8 19.7 36.4 44.9 2.6 5.6 8.0 23.7 6.7 16.6 19.3 6.3 18.2 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 119.8;Endometrial stromal cells: 37.9;Leydig cells: 34.5;Peritubular cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 7 "dendritic cells: 5.4;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "HHSteC: 16.1;HSkMC: 30.6;hTCEpi: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048682, HPA053453" Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 76000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA048682: AB_2680492, HPA053453: AB_2682155" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" 16.1 6.6 15.7 8.4 17.0 2.3 10.7 12.1 23.5 30.3 15.7 13.4 3.0 20.4 14.9 7.1 23.0 5.6 8.0 14.4 13.3 42.6 3.2 13.4 15.2 14.1 14.6 16.8 4.0 0.4 16.4 4.0 13.1 13.6 4.5 9.5 7.5 7.5 2.1 15.7 17.8 6.3 12.3 29.1 11.3 6.4 14.4 5.1 24.8 1.8 13.6 5.1 9.1 12.3 2.7 2.6 1.0 0.4 1.9 2.3 5.8 0.5 0.0 0.1 0.2 3.4 0.8 0.5 2.7 0.0 0.1 4.3 2.7 2.0 0.3 3.0 3.9 1.2 4.7 0.3 16.1 0.4 2.1 30.6 11.4 0.5 1.7 0.2 0.6 2.5 0.8 0.3 0.0 1.4 0.3 3.0 0.6 0.3 0.8 0.4 0.3 2.8 2.3 0.6 0.3 0.5 6.2 7.0 1.3 7.9 0.2 4.8 0.5 0.7 2.3 0.2 0.3 1.3 0.1 0.3 1.4 1.4 0.6 0.8 0.5 0.3 0.2 0.3 0.1 0.4 0.1 0.2 0.1 0.5 0.2 0.2 2.5 0.3 0.2 5.4 0.3 0.1 15.7 17.0 12.1 23.5 14.4 13.3 14.1 14.6 13.1 12.3 14.4 12.3 0.4 0.0 2.6 119.8 0.3 2.0 0.7 5.1 0.6 1.2 1.8 1.4 1.9 7.2 4.8 5.5 8.4 0.5 5.7 0.4 0.0 4.0 0.3 11.8 37.9 3.4 0.0 0.0 0.3 0.0 1.1 8.3 0.5 16.1 0.0 0.2 3.3 0.1 1.2 0.0 0.9 0.4 2.0 0.3 1.6 1.7 34.5 1.8 1.8 10.3 1.6 15.7 0.0 3.0 0.3 0.4 0.0 44.0 0.2 1.4 0.2 10.2 3.7 3.0 6.6 1.4 1.8 0.6 0.1 0.8 3.0 0.4 0.7 0.1 1.0 0.4 PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153791-116402321 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 72.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 92.2;Collecting duct cells: 165.5;Endometrial stromal cells: 101.3;Proximal tubular cells: 51.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 50.0;ASC TERT1: 37.8;HSkMC: 137.4;U-138 MG: 36.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" NA NA 78000000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" 4.1 1.5 0.7 1.8 0.2 0.0 0.8 0.5 0.9 4.2 2.2 2.0 0.3 3.9 0.6 2.5 3.1 2.0 2.6 0.3 1.6 3.8 0.3 1.9 1.2 2.5 2.5 2.5 0.8 9.1 0.4 72.3 2.0 1.1 1.5 1.0 0.4 2.1 0.3 0.9 0.9 4.2 0.4 0.3 1.1 0.8 1.6 0.8 1.0 1.4 1.0 4.5 2.4 1.3 0.0 14.9 22.3 0.0 50.0 37.8 0.0 12.2 21.4 3.3 5.6 0.0 0.0 0.0 0.0 8.6 1.1 1.7 0.0 0.0 15.6 0.0 0.0 2.6 12.8 0.1 24.3 0.0 0.0 137.4 0.0 16.4 1.9 26.9 0.1 0.0 0.5 0.0 3.8 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.0 0.6 0.1 0.1 1.2 1.8 0.0 0.0 6.8 0.0 0.0 28.9 36.3 1.8 1.0 1.4 0.0 0.0 0.0 25.8 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.5 0.9 0.3 1.6 2.5 2.5 2.0 0.4 1.6 1.3 0.2 0.0 1.5 3.9 1.0 2.9 0.2 4.0 92.2 17.6 0.8 0.4 3.4 0.0 1.6 165.5 12.5 0.5 0.1 0.1 9.8 5.9 20.1 4.7 101.3 1.4 0.0 0.0 10.0 0.9 19.5 31.8 0.5 2.6 1.3 10.4 4.6 0.1 0.4 0.0 19.6 0.0 0.0 0.0 5.8 17.9 14.3 1.0 1.8 7.5 0.0 2.5 1.0 15.1 2.9 0.3 0.0 8.6 1.2 1.2 0.2 51.5 1.6 2.9 0.0 3.3 10.9 2.2 0.6 19.7 1.1 14.0 1.3 0.2 0.1 0.3 PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845601 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 56.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 140.7;Extravillous trophoblasts: 71.9;Muller glia cells: 41.4;Oligodendrocytes: 37.6;Syncytiotrophoblasts: 74.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-87 MG: 19.8" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 5.6" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" NA NA 2000000 "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Endoplasmic reticulum, Vesicles" "HPA018412: AB_1854962, HPA018430: AB_1854961" "unprognostic (2.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.39e-2)" "unprognostic (2.85e-2)" "unprognostic (1.52e-4)" "unprognostic (1.85e-1)" "unprognostic (8.18e-4)" "unprognostic (4.35e-2)" 0.6 0.0 0.5 0.3 0.3 0.0 2.5 0.3 0.4 6.6 0.0 0.6 0.0 0.6 0.3 0.0 0.2 1.8 0.3 0.5 0.2 6.3 0.6 0.1 0.0 0.5 0.5 0.0 2.5 0.0 1.1 56.8 0.6 0.2 0.5 3.7 0.1 0.6 0.0 0.1 0.2 0.5 0.4 0.0 1.6 0.4 0.3 0.0 0.5 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 4.3 2.1 3.5 0.9 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.7 0.5 0.5 0.2 0.0 0.0 0.1 0.7 0.0 0.0 0.3 1.6 1.3 0.1 0.6 0.3 0.4 0.0 19.8 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.4 0.5 0.2 0.5 0.5 0.6 0.4 0.3 0.4 0.0 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.1 0.8 0.0 0.0 5.5 0.0 1.5 0.0 0.1 11.7 0.0 2.6 0.2 0.1 0.3 140.7 0.0 16.3 0.2 71.9 0.8 0.0 0.0 0.0 0.0 0.0 0.6 1.3 0.0 10.8 0.2 0.0 0.0 0.0 1.9 11.5 0.0 0.0 2.8 0.0 41.4 0.0 5.0 37.6 0.8 0.0 10.9 0.0 0.0 0.0 0.5 0.0 2.4 6.6 0.0 1.2 1.3 2.2 0.0 0.0 74.0 0.0 0.0 0.2 0.1 PATE1 PATE ENSG00000171053 "Prostate and testis expressed 1" Q8WXA2 11 125746279-125749867 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "epididymis: 1868.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;NB-4: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA076587 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA076587: AB_2732316" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1868.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PATE2 "C11orf38, LVLF3112, PATE-M, UNQ3112" ENSG00000196844 "Prostate and testis expressed 2" Q6UY27 11 125776113-125778828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "epididymis: 450.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.4;Early spermatids: 4.4;Excitatory neurons: 2.7;Inhibitory neurons: 3.1;Late spermatids: 13.7;Oligodendrocyte precursor cells: 3.0;Spermatocytes: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.28e-1)" "unprognostic (7.26e-2)" "unprognostic (2.95e-1)" "unprognostic (1.18e-2)" "unprognostic (2.63e-1)" "unprognostic (6.84e-3)" "unprognostic (1.55e-2)" "unprognostic (5.08e-1)" "unprognostic (2.55e-1)" 0.0 0.1 0.5 0.0 0.6 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 450.6 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.4 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.7 0.4 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.2 0.9 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.8 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PATE3 "HEL-127, PATE-DJ" ENSG00000236027 "Prostate and testis expressed 3" B3GLJ2 11 125788127-125791600 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "epididymis: 158.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 25: Spermatids - Spermatogenesis" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 158.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PATE4 "FLJ41047, PATE-B" ENSG00000237353 "Prostate and testis expressed 4" P0C8F1 11 125833316-125840072 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "seminal vesicle: 106.8" "Group enriched" "Detected in some" 70 "Early spermatids: 22.9;Late spermatids: 19.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045632 Approved "Secreted in male reproductive system" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Spermatids - Unknown function" "HPA045632: AB_10960489" "unprognostic (4.90e-1)" "unprognostic (2.93e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" 0.1 0.2 0.7 0.1 0.6 0.4 0.1 1.8 1.3 0.1 0.0 0.0 0.1 0.1 14.9 0.1 0.1 0.1 0.1 0.5 0.2 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 2.9 0.1 0.7 0.1 106.8 0.2 0.4 0.1 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.4 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.4 0.2 0.3 0.5 0.2 0.3 0.1 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.6 1.8 1.3 0.5 0.2 0.0 0.0 0.1 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCDHA1 ENSG00000204970 "Protocadherin alpha 1" Q9Y5I3 5 140786136-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;pituitary gland: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.2;Hepatic stellate cells: 1.4;Sertoli cells: 6.6;Spermatogonia: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "T-47d: 9.1" "Low region specificity" "Detected in many" HPA035969 Enhanced Approved "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA035969: AB_10673492" "unprognostic (2.76e-5)" "unprognostic (1.19e-1)" "unprognostic (3.74e-2)" "unprognostic (1.09e-4)" "unprognostic (7.38e-2)" "unprognostic (2.86e-2)" "unprognostic (2.26e-3)" "unprognostic (1.25e-2)" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (9.01e-5)" "unprognostic (2.46e-2)" "unprognostic (1.91e-1)" "unprognostic (7.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (1.29e-1)" 0.0 0.2 0.2 0.0 0.5 0.0 0.1 1.5 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.0 0.0 0.0 1.5 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 1.1 0.1 9.1 0.3 0.0 1.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.5 1.0 0.7 0.4 1.5 0.7 1.1 0.9 0.5 1.9 0.0 3.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHA10 "CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10" ENSG00000250120 "Protocadherin alpha 10" Q9Y5I2 5 140855883-141012347 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3;pancreas: 4.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.3;Cone photoreceptor cells: 8.4;Horizontal cells: 8.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 16.2" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (4.24e-2)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (4.70e-2)" "unprognostic (4.19e-1)" "unprognostic (2.36e-1)" "unprognostic (6.46e-2)" "unprognostic (8.24e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-2)" "unprognostic (2.65e-1)" "unprognostic (6.14e-3)" "unprognostic (1.93e-2)" "unprognostic (3.57e-3)" "unprognostic (5.21e-2)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" 0.8 0.5 1.3 0.3 1.8 0.1 0.7 6.3 2.4 0.9 0.0 0.2 0.3 1.8 2.0 0.0 1.0 1.2 0.1 1.6 0.7 1.5 0.0 0.8 0.2 2.1 1.0 1.1 4.1 0.7 1.5 0.0 2.0 0.4 0.1 2.4 0.5 0.2 0.1 0.1 0.7 1.6 1.5 0.1 0.3 1.3 1.1 0.0 2.1 0.1 0.0 0.2 0.1 2.7 0.0 0.2 0.5 3.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.3 1.2 0.8 0.0 0.1 0.0 2.4 0.3 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 6.3 2.4 1.6 0.7 2.1 1.0 2.0 1.5 1.1 2.7 0.9 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 7.3 1.2 1.4 0.6 1.5 0.1 0.0 8.4 0.0 0.0 0.2 0.0 0.2 3.2 0.6 2.7 0.6 1.8 0.0 0.0 0.9 0.0 0.6 0.0 0.5 0.0 0.3 0.4 0.0 0.0 8.4 0.0 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.9 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 3.2 0.0 2.5 2.3 2.2 0.3 0.0 0.0 0.0 0.2 0.3 0.1 0.3 PCDHA6 "CNR2, CNRS2, CRNR2, PCDH-ALPHA6" ENSG00000081842 "Protocadherin alpha 6" Q9UN73 5 140827958-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;EFO-21: 8.4;hTERT-RPE1: 2.2;U-2 OS: 3.4;WM-115: 5.2" "Low region specificity" "Detected in many" "HPA059326, HPA078110" Enhanced Approved Vesicles "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 38: EFO-21 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA059326: AB_2683980, HPA078110: AB_2732371" "unprognostic (1.15e-1)" "unprognostic (7.00e-2)" "unprognostic (5.07e-1)" "unprognostic (2.79e-1)" "unprognostic (4.39e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-4)" "unprognostic (4.23e-3)" "unprognostic (8.38e-2)" "unprognostic (2.55e-1)" "unprognostic (1.23e-3)" "unprognostic (3.44e-1)" "unprognostic (1.03e-2)" "unprognostic (2.66e-3)" "unprognostic (2.56e-1)" "unprognostic (5.66e-3)" "unprognostic (3.55e-2)" 0.2 0.3 0.8 0.1 0.9 0.0 0.3 4.1 1.1 0.4 0.0 0.1 0.2 0.6 0.3 0.0 0.3 0.3 0.1 1.0 0.7 0.4 0.0 0.2 0.1 0.4 0.3 0.4 1.0 1.5 1.5 0.0 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.1 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 1.0 0.1 0.4 0.0 1.3 0.0 3.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 4.1 1.1 1.0 0.7 0.4 0.3 0.5 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PCSK1 "NEC1, PC1, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390333-96434143 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 68.3" "Cell type enriched" "Detected in some" 4 "Enteroendocrine cells: 224.6" "Cancer enhanced" "Detected in many" "breast cancer: 12.1" "Group enriched" "Detected in all" 5 "cerebral cortex: 19.1;hypothalamus: 68.3;pons: 30.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 22.6;U-138 MG: 19.0;U-87 MG: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048564, HPA079656" Approved "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA048564: AB_2680444, HPA079656: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavorable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" 1.7 6.3 5.5 4.7 3.7 0.1 1.4 1.0 19.1 0.9 0.0 2.4 5.2 0.1 0.0 0.1 0.2 0.2 0.8 3.0 68.3 0.4 0.0 0.3 0.1 6.6 7.7 0.4 7.6 0.0 12.1 0.0 30.0 0.4 2.3 8.7 2.7 0.1 0.3 1.1 3.6 0.6 4.0 0.1 5.7 0.1 6.6 0.2 1.9 0.0 0.0 2.0 0.5 5.3 0.0 0.0 0.3 0.0 2.3 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 1.0 3.8 0.0 0.0 0.1 0.0 0.1 0.1 0.8 2.4 0.0 0.0 0.0 0.0 2.0 1.0 0.4 0.1 0.2 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 3.3 0.0 0.0 0.4 0.0 0.0 1.2 19.0 0.6 0.3 0.2 0.0 0.0 0.1 15.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 3.7 1.0 19.1 3.0 68.3 6.6 7.7 30.0 4.0 6.6 5.3 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 1.8 13.2 0.0 0.0 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.2 0.2 224.6 0.0 54.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 4.0 10.7 2.0 0.0 0.4 1.6 0.0 0.0 0.0 4.7 0.0 0.5 0.0 3.5 4.9 1.5 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.9 0.0 1.7 1.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.7 0.0 PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 642.6;pituitary gland: 1243.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 3045.7;Horizontal cells: 437.4;Paneth cells: 628.8;Proximal tubular cells: 1601.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "HEK 293: 58.9;PC-3: 148.5;SCLC-21H: 58.2;SH-SY5Y: 53.8;SiHa: 52.1;U-266/84: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" NA NA 3300000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favorable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" 2.2 29.5 177.1 0.5 135.6 0.0 2.0 21.6 212.8 18.2 118.8 19.2 9.6 34.1 2.9 0.9 6.9 0.2 16.0 105.6 642.6 152.1 1.3 2.9 0.1 290.3 257.1 2.3 54.0 11.1 1243.7 0.2 193.0 14.4 0.5 2.5 6.7 0.8 0.8 8.8 13.7 0.6 95.5 1.1 21.9 19.7 264.9 0.0 3.3 0.0 0.0 1.2 6.5 51.8 0.1 5.4 0.2 14.9 0.6 0.0 0.4 0.0 0.0 0.0 0.0 5.3 0.1 0.0 10.4 0.0 4.2 0.8 0.0 1.1 0.0 0.0 58.9 0.0 0.0 9.3 0.0 0.0 3.7 0.0 0.8 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.0 7.6 0.0 0.5 7.9 0.0 148.5 0.0 0.0 0.4 1.4 0.2 58.2 53.8 52.1 0.2 4.9 0.7 0.2 0.1 0.1 0.1 22.7 0.2 5.0 13.3 73.6 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.8 0.0 2.4 0.0 5.0 4.9 0.0 0.0 2.0 6.4 0.0 0.0 0.0 0.0 1.8 0.7 177.1 135.6 21.6 212.8 105.6 642.6 290.3 257.1 193.0 95.5 264.9 51.8 0.8 0.0 0.0 29.0 12.5 15.8 1.3 4.3 0.6 139.6 11.4 14.9 1.4 2.8 4.3 389.9 52.1 1.0 1.0 18.2 277.8 8.6 12.8 44.3 8.7 3.6 3045.7 2.7 64.8 0.7 69.0 17.2 112.1 35.2 0.0 2.5 0.0 0.5 1.7 437.4 118.8 218.9 54.9 0.3 17.2 52.9 3.4 10.5 56.9 22.5 0.4 96.2 1.0 72.9 26.0 23.1 628.8 7.2 4.5 30.4 21.6 1601.1 24.8 148.2 0.0 0.3 12.6 32.5 82.2 0.2 11.5 1.9 20.1 0.2 15.6 3.7 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 28.5;brain: 30.2;retina: 35.8;thyroid gland: 56.9" "Cell type enhanced" "Detected in many" "Early spermatids: 87.3;Excitatory neurons: 322.8;Horizontal cells: 132.9;Inhibitory neurons: 148.8;Melanocytes: 209.9;Muller glia cells: 452.7" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 65.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 60.0;SCLC-21H: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" NA NA 18000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA049627: AB_2680835" "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 0.7 28.5 8.6 0.8 14.9 0.5 0.4 0.1 30.2 1.6 0.0 6.9 4.8 0.2 0.3 1.1 1.0 0.5 4.7 15.8 11.1 0.2 0.2 2.5 0.0 2.2 1.3 9.0 19.8 0.8 2.0 0.6 2.6 1.4 1.7 35.8 1.7 1.2 0.1 14.1 2.1 0.4 1.4 0.1 8.1 4.8 13.2 0.0 56.9 0.1 0.1 3.0 2.4 11.9 0.0 0.0 60.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 14.9 0.1 30.2 15.8 11.1 2.2 1.3 2.6 1.4 13.2 11.9 0.1 0.0 7.3 7.8 0.0 8.2 0.0 0.0 1.2 28.1 0.0 0.0 1.2 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.0 87.3 0.0 0.0 1.3 0.0 0.0 322.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 132.9 148.8 0.6 0.0 0.0 1.3 6.3 2.8 0.2 209.9 8.4 0.0 452.7 0.0 44.7 6.4 2.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.5 1.2 1.0 0.3 0.2 1.4 0.0 0.1 0.6 0.0 0.1 PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 189.7;Inhibitory neurons: 81.9;NK-cells: 82.4;Oligodendrocyte precursor cells: 149.3;Proximal enterocytes: 99.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 2447.1;neutrophil: 626.3" "Lineage enriched" "Detected in all" 18 "granulocytes: 2447.1" "Cell line enhanced" "Detected in many" "BEWO: 32.6;HaCaT: 46.9;RH-30: 30.4;RPTEC TERT1: 42.5;U-2 OS: 66.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" NA NA 290000 "Cluster 41: Basophils - Cellular respiration" "Cluster 45: Intestine - Brush border" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" 17.6 4.2 6.6 5.9 6.6 2.3 6.9 22.2 23.8 9.0 0.0 10.2 25.0 7.1 9.6 8.5 6.9 8.6 5.3 7.4 7.8 3.8 1.7 6.1 2.7 21.7 17.3 13.5 3.0 5.9 2.3 9.4 20.0 3.3 8.4 6.0 3.5 3.0 3.0 3.6 26.4 6.6 23.0 3.3 3.3 6.3 5.3 9.1 4.8 5.4 2.5 5.3 8.8 2.4 2.5 1.8 5.1 3.4 3.2 1.0 32.6 4.7 0.4 0.3 0.0 18.7 2.0 0.8 1.3 0.6 0.1 46.9 2.4 1.4 0.3 0.6 4.1 6.3 4.5 1.6 0.8 1.9 2.8 6.0 0.4 1.0 0.5 0.3 9.6 3.1 7.5 2.4 3.3 11.5 7.4 11.1 22.8 4.3 1.9 1.3 30.4 1.9 42.5 2.9 0.7 0.5 7.1 1.5 0.5 9.5 2.6 8.0 7.6 1.5 66.5 3.8 2.0 0.7 0.3 1.0 5.1 2.7 25.7 2447.1 43.1 192.4 100.0 25.9 85.2 92.3 100.8 93.7 21.8 116.5 98.2 125.2 626.3 135.5 51.6 135.0 96.9 10.1 6.6 6.6 22.2 23.8 7.4 7.8 21.7 17.3 20.0 23.0 5.3 2.4 41.1 6.4 7.2 189.7 0.1 6.5 3.5 8.6 13.6 4.8 0.7 2.0 5.8 11.5 14.3 5.5 0.0 2.1 9.6 47.3 0.0 8.2 19.0 6.0 35.1 19.5 1.2 0.0 33.5 6.1 34.3 26.6 9.7 10.6 0.0 32.1 15.0 0.9 2.9 55.5 81.9 10.2 6.1 4.1 3.9 39.4 20.5 7.5 1.8 70.3 11.4 30.3 82.4 149.3 5.8 10.1 18.5 25.2 0.4 2.9 99.2 4.2 23.4 1.4 19.7 9.1 11.4 1.0 1.9 6.2 3.0 2.5 6.2 5.6 23.9 0.9 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 153.6;liver: 160.0;lymphoid tissue: 81.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 231.6;Horizontal cells: 196.9;Oligodendrocytes: 561.9;Theca cells: 106.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.2;CACO-2: 35.7;HEK 293: 60.3;Hep G2: 53.8;OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" NA NA 480000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 5.3 2.2 17.5 3.0 67.3 1.1 11.2 57.8 37.0 2.2 4.2 16.5 6.8 2.0 3.3 9.0 2.8 3.1 20.0 19.3 34.1 3.2 160.0 3.6 2.5 113.0 64.5 6.1 2.6 0.6 5.1 32.0 95.6 3.1 14.8 7.6 2.8 0.6 11.4 10.1 10.1 3.6 42.9 81.4 9.8 13.0 54.0 20.9 2.2 16.3 1.8 3.7 2.6 153.6 19.7 14.6 2.6 0.9 0.2 0.4 47.2 0.7 2.5 0.0 0.1 35.7 8.3 0.4 2.4 0.6 1.1 11.4 12.5 1.5 0.0 2.8 60.3 33.5 8.4 53.8 1.6 4.5 0.4 0.3 7.5 0.2 0.2 0.2 0.1 4.3 24.5 0.2 0.0 8.8 0.1 4.7 9.3 65.9 6.5 0.2 0.4 4.4 4.4 25.4 7.3 8.6 26.2 1.5 9.1 6.6 2.2 21.9 0.2 0.3 1.2 0.3 0.2 0.5 0.6 0.7 0.2 0.6 7.3 0.8 0.2 0.9 0.2 0.4 0.3 0.5 0.4 0.2 0.1 1.0 0.6 0.5 0.4 3.3 1.3 0.4 0.1 1.2 17.5 67.3 57.8 37.0 19.3 34.1 113.0 64.5 95.6 42.9 54.0 153.6 1.7 3.2 0.6 2.9 1.3 0.4 0.3 0.9 0.6 1.7 15.4 6.6 2.0 8.6 1.4 1.8 20.9 6.7 0.6 22.6 0.0 0.6 1.6 4.7 21.6 4.9 0.0 3.2 19.4 0.8 24.3 15.5 1.5 6.9 0.0 4.2 12.5 231.6 1.4 196.9 30.8 3.7 0.0 5.2 1.1 2.4 10.5 1.7 0.0 5.6 1.0 1.7 3.1 25.6 561.9 7.3 8.2 0.0 0.0 1.7 2.3 0.1 1.2 1.6 0.0 2.0 1.0 4.7 2.4 0.9 0.1 3.3 1.0 106.5 8.5 0.2 PCSK9 "FH3, HCHOLA3, NARC-1" ENSG00000169174 "Proprotein convertase subtilisin/kexin type 9" Q8NBP7 1 55039447-55064852 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 48.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 22.4;Gastric mucus-secreting cells: 8.2;Hepatocytes: 32.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;medulla oblongata: 2.1;pons: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 82.5;CACO-2: 37.0;HaCaT: 108.8;HeLa: 90.7;RPTEC TERT1: 56.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 143000000 420000000 "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.28e-3)" "unprognostic (6.93e-2)" "unprognostic (4.02e-1)" "unprognostic (2.19e-2)" "unprognostic (7.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-3)" "unprognostic (1.14e-2)" "unprognostic (5.44e-3)" "unprognostic (1.22e-2)" "unprognostic (2.09e-3)" "unprognostic (3.70e-2)" "unprognostic (2.45e-4)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (2.40e-4)" 0.3 0.2 0.0 0.7 0.1 0.4 0.1 3.4 0.3 1.0 0.0 4.5 3.1 0.3 0.3 5.5 0.4 0.1 0.0 0.1 0.1 0.1 48.7 7.9 0.0 2.1 0.3 0.1 5.4 0.2 0.1 0.0 2.0 0.0 1.6 0.0 0.5 0.2 0.0 1.4 3.4 0.7 0.0 0.3 1.3 0.4 0.1 0.0 0.0 0.0 0.3 0.4 1.5 0.2 82.5 17.6 2.8 0.0 6.4 4.4 0.2 0.0 0.0 0.2 0.2 37.0 13.2 0.0 13.9 7.8 0.3 108.8 3.5 35.2 0.0 0.0 0.0 0.0 90.7 26.5 2.2 0.0 0.0 6.4 25.5 25.2 18.4 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 15.1 1.5 1.9 0.0 0.0 0.9 56.4 0.1 1.3 0.0 10.5 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.3 0.1 0.1 2.1 0.3 2.0 0.0 0.1 0.2 0.0 16.0 22.4 0.0 0.2 0.5 0.0 2.1 1.2 0.0 0.0 0.0 0.6 0.0 1.8 0.0 0.0 0.0 0.0 2.0 0.0 0.5 0.2 0.8 0.1 0.1 4.2 2.7 0.1 1.5 0.0 0.6 8.2 0.8 0.0 0.1 1.1 32.9 0.1 0.0 0.1 4.3 2.0 1.6 0.5 0.6 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.6 1.3 1.4 0.6 0.0 0.1 0.0 5.4 0.4 PCYOX1L MGC3265 ENSG00000145882 "Prenylcysteine oxidase 1 like" Q8NBM8 5 149358037-149369653 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 17.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 50.2;RPMI-8226: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037463, HPA038402" Approved Approved Nucleoplasm,Mitochondria "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Mitochondria" "HPA037463: AB_10673632, HPA038402: AB_2675997" "unprognostic (1.34e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (7.83e-2)" "unprognostic (5.73e-2)" "unprognostic (4.18e-3)" "unprognostic (7.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.25e-1)" "unprognostic (3.05e-3)" "unprognostic (8.77e-2)" "unprognostic (4.90e-2)" "unprognostic (2.86e-1)" "unprognostic (2.49e-1)" "unprognostic (2.26e-3)" "unprognostic (3.28e-1)" 3.2 4.6 2.3 5.3 2.4 3.9 3.3 2.4 4.5 5.1 0.2 3.2 1.8 4.9 0.6 3.5 5.3 4.7 3.9 2.9 4.4 2.0 0.5 3.4 6.6 3.7 2.5 5.7 3.1 17.5 4.9 4.2 5.0 3.9 0.7 7.6 2.9 4.5 0.8 5.4 4.8 5.2 1.0 4.0 3.7 6.4 2.3 4.6 2.7 1.8 3.2 3.8 3.8 2.3 4.3 2.7 9.2 20.3 7.8 7.9 4.9 9.0 4.0 7.8 13.2 0.8 7.6 17.9 27.1 6.7 36.1 7.7 8.8 20.3 0.7 8.4 8.2 8.4 0.0 0.7 17.3 7.3 9.1 14.9 3.0 10.7 12.6 9.4 17.3 16.6 4.9 50.2 0.4 17.9 8.1 11.2 4.7 15.8 16.3 10.7 6.7 50.8 4.9 2.0 13.3 13.6 17.9 11.9 14.6 10.0 20.0 12.4 8.2 6.8 5.5 14.7 4.2 20.1 29.2 10.6 11.2 38.3 14.6 3.0 7.1 4.0 2.8 9.6 3.7 1.6 5.3 2.1 13.2 1.0 6.3 4.4 1.2 4.8 9.6 0.9 7.3 4.7 2.3 2.4 2.4 4.5 2.9 4.4 3.7 2.5 5.0 1.0 2.3 2.3 4.5 9.6 1.7 2.9 2.3 1.0 1.0 3.2 2.8 5.2 2.4 1.8 5.3 4.3 3.6 1.8 0.0 6.0 1.9 0.6 0.0 3.0 3.3 3.2 2.4 4.6 0.0 2.5 10.5 2.3 6.6 5.0 2.0 2.3 2.5 9.6 2.5 0.4 7.6 11.8 12.4 1.8 6.1 8.2 1.4 1.5 3.4 6.9 1.8 4.7 7.0 7.8 1.0 5.5 4.9 2.1 1.7 2.6 1.3 0.8 2.6 0.6 2.8 14.2 0.0 2.5 2.7 1.2 3.5 1.9 1.6 1.2 5.6 9.7 2.3 0.9 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDGFA "PDGF-A, PDGF1" ENSG00000197461 "Platelet derived growth factor subunit A" P04085 7 497258-520296 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 95.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 89.8;Breast myoepithelial cells: 154.9;Paneth cells: 97.0;Smooth muscle cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 11.3" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "WM-115: 311.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005579, HPA065024" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 580000 "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "CAB005579: AB_2161916, HPA065024: " "unprognostic (2.22e-1)" "unprognostic (2.83e-1)" "unprognostic (1.17e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.75e-4)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.63e-3)" "unprognostic (4.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.85e-1)" "unprognostic (8.26e-2)" "unprognostic (1.07e-2)" "unprognostic (5.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (8.67e-4)" 15.4 8.5 29.3 7.9 36.8 1.7 17.0 36.6 32.4 18.1 20.5 29.2 20.2 26.1 11.2 9.6 21.2 11.4 21.1 27.0 27.5 22.2 8.5 24.9 3.5 46.4 37.5 7.7 71.6 6.6 10.2 26.8 40.7 23.3 14.8 5.2 20.3 11.2 95.2 12.5 25.9 10.2 35.8 16.3 32.1 4.5 36.5 6.6 10.0 15.1 2.4 17.8 15.9 58.8 22.9 15.3 1.5 21.6 4.1 0.7 50.7 5.0 2.9 6.4 4.4 23.8 25.3 0.6 8.7 4.3 2.9 56.6 1.5 69.0 3.4 12.9 2.3 0.3 13.3 8.7 26.9 2.4 2.2 3.0 26.8 3.3 21.3 8.5 12.5 1.3 2.3 3.1 15.8 28.7 3.5 5.0 40.1 8.9 3.3 11.6 1.5 2.5 9.0 5.3 2.1 1.8 76.5 4.2 13.3 47.5 10.7 2.6 37.3 13.6 37.8 8.0 31.0 0.9 1.4 0.8 12.3 7.1 311.4 11.3 1.6 2.4 1.6 1.9 2.2 1.9 1.6 1.5 1.5 1.8 1.9 2.0 4.9 3.4 3.3 2.1 1.8 2.1 29.3 36.8 36.6 32.4 27.0 27.5 46.4 37.5 40.7 35.8 36.5 58.8 15.2 89.8 11.9 11.1 1.5 28.0 20.2 12.1 59.7 15.7 12.7 154.9 29.9 15.7 11.0 14.7 8.4 8.8 1.7 76.9 5.9 15.8 0.3 49.0 4.2 19.4 13.1 0.0 7.7 53.3 5.4 12.3 41.8 35.7 10.8 18.1 21.0 1.0 2.0 32.0 5.9 40.5 2.0 1.3 10.4 0.1 2.1 14.8 14.2 6.5 1.5 0.7 1.0 5.0 27.5 72.6 97.0 6.4 4.4 29.4 47.2 8.5 4.5 2.1 39.5 48.9 110.3 0.5 1.8 9.4 9.8 2.9 3.9 0.2 32.1 18.2 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 98.6;Granulosa cells: 124.1;Microglial cells: 85.3;Oligodendrocyte precursor cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 60.0;hTERT-RPE1: 56.8;U-138 MG: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" NA NA 37000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA009134: AB_10601981" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (5.79e-2)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (3.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.35e-5)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.17e-4)" 4.8 4.0 0.9 1.3 1.0 0.6 7.5 0.4 1.0 9.2 0.7 2.3 2.0 9.9 2.1 3.3 6.7 4.8 2.6 1.0 0.8 5.5 5.1 3.1 1.1 0.8 0.7 7.7 4.3 20.3 0.4 4.5 0.7 8.7 2.0 0.7 8.4 7.0 1.2 1.6 2.8 9.4 0.9 1.3 2.8 0.9 1.1 2.0 6.5 1.2 1.0 3.2 1.2 1.0 2.5 3.7 38.6 25.4 7.0 13.4 1.0 21.5 21.5 12.0 16.1 2.2 9.4 0.0 3.8 60.0 9.2 2.6 10.8 13.4 16.5 0.0 5.0 25.5 3.2 2.4 18.3 3.9 0.3 14.2 6.6 30.6 21.7 56.8 6.0 0.1 0.1 0.1 30.2 0.1 0.0 0.0 0.4 0.0 1.7 0.0 8.1 0.0 22.5 0.9 0.0 0.0 0.0 0.2 0.4 6.0 3.1 1.3 28.3 41.7 0.4 10.9 17.3 0.0 0.0 0.0 16.1 0.0 1.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.9 1.0 0.4 1.0 1.0 0.8 0.8 0.7 0.7 0.9 1.1 1.0 2.4 6.4 14.2 98.6 0.7 49.6 22.7 12.4 25.0 2.0 14.7 13.6 16.8 58.6 7.8 12.9 0.0 0.6 3.4 0.5 0.0 15.4 30.5 6.9 15.0 7.3 0.0 5.5 64.4 7.1 0.3 18.6 8.2 11.4 1.3 124.1 10.0 15.9 13.0 0.0 32.1 2.1 4.1 34.4 21.6 23.8 5.3 32.1 10.6 85.3 14.2 6.3 0.0 233.2 3.0 18.0 0.5 23.0 1.4 8.7 2.4 18.6 3.5 0.5 6.6 34.8 18.2 0.7 2.9 3.4 13.5 0.5 0.9 13.8 2.1 4.8 PDGFD "IEGF, MSTP036, SCDGF-B" ENSG00000170962 "Platelet derived growth factor D" Q9GZP0 11 103907189-104164379 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 106.5;ovary: 78.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;dendritic cells: 30.0;Ductal cells: 30.6;Fibroblasts: 44.3;Inhibitory neurons: 95.0;Microglial cells: 28.1;NK-cells: 46.4" "Cancer enhanced" "Detected in all" "renal cancer: 17.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "eosinophil: 9.5;gdT-cell: 16.4;memory CD8 T-cell: 7.2;naive CD8 T-cell: 6.0;NK-cell: 17.1" "Group enriched" "Detected in many" 29 "granulocytes: 9.5;NK-cells: 17.1;T-cells: 16.4" "Group enriched" "Detected in many" 6 "ASC diff: 139.8;HHSteC: 42.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 39.4" "HPA046183, HPA066271" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 95000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA046183: AB_2679573, HPA066271: AB_2685645" "unprognostic (2.21e-1)" "unprognostic (9.35e-2)" "unprognostic (5.60e-2)" "unprognostic (1.72e-1)" "unprognostic (5.81e-2)" "unprognostic (8.83e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (2.26e-1)" "unprognostic (7.01e-3)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.19e-1)" "unprognostic (6.72e-2)" "unprognostic (3.57e-3)" 20.4 106.5 0.5 3.4 0.8 0.9 21.7 0.7 1.3 25.1 9.0 8.8 4.1 11.8 7.1 1.9 9.3 34.0 23.2 0.8 2.2 7.7 2.3 3.1 7.4 5.1 6.6 78.0 25.7 17.1 13.4 7.0 9.4 10.0 9.8 1.5 8.6 37.4 2.2 7.9 4.8 9.7 1.8 2.8 23.4 3.3 2.0 3.7 18.3 8.8 5.4 15.8 15.4 2.3 0.0 7.8 4.0 0.0 139.8 4.2 0.1 0.9 0.8 0.7 0.8 0.0 1.3 7.4 1.4 7.3 5.2 0.4 0.0 0.2 0.3 0.0 3.2 0.2 1.6 0.3 42.6 0.0 0.1 14.7 0.0 0.1 0.0 0.2 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 1.4 0.0 2.1 0.0 6.7 0.0 0.1 9.6 0.0 13.8 3.2 1.8 0.0 2.0 1.0 0.1 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.8 0.6 0.0 9.5 16.4 0.0 1.4 0.4 1.7 7.2 0.0 0.0 0.2 6.0 0.2 17.1 0.1 0.0 0.1 4.2 0.5 0.8 0.7 1.3 0.8 2.2 5.1 6.6 9.4 1.8 2.0 2.3 15.6 0.0 0.0 1.0 1.6 3.1 7.7 0.2 1.8 2.3 1.7 9.4 4.5 32.9 0.6 5.5 0.0 0.2 30.0 0.2 0.0 30.6 8.2 0.8 1.8 10.3 1.8 1.3 13.9 4.4 0.2 44.3 0.0 1.4 0.0 8.1 2.9 0.0 0.3 26.9 95.0 1.0 0.0 1.3 3.7 13.3 0.3 0.8 0.0 28.1 0.9 1.5 46.4 2.0 2.8 3.0 0.5 2.2 8.4 1.6 0.0 0.3 0.0 0.5 6.6 1.9 3.7 0.4 4.3 0.3 2.0 0.0 10.2 5.2 0.6 3.2 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 PDYN "ADCA, PENKB, SCA23" ENSG00000101327 Prodynorphin P01213 20 1978757-1994285 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Neurotransmitter, Opioid peptide" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 47.0" "Group enriched" "Detected in some" 83 "Early spermatids: 47.8;Late spermatids: 119.0" "Group enriched" "Detected in some" 29 "glioma: 2.6;ovarian cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.0" "Group enriched" "Detected in many" 4 "basal ganglia: 152.2;hypothalamus: 60.7" "Region enhanced" "Detected in many" "basal ganglia: 132.2" "HPA053342, CAB079777" Enhanced Supported "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "CAB079777: , HPA053342: AB_2682121" "unprognostic (7.00e-2)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (3.73e-2)" 0.0 0.0 43.2 0.1 31.1 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.0 17.6 0.0 0.0 0.0 0.0 1.8 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 21.0 0.0 0.0 8.3 9.2 0.2 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.2 31.1 0.0 43.1 47.0 17.6 1.8 4.1 0.2 21.0 9.2 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 119.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 382.5;skeletal muscle: 670.8;tongue: 581.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 109.0;Alveolar cells type 2: 177.3;Cardiomyocytes: 144.7;Muller glia cells: 198.7" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-266/70: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" NA NA 190000000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" 1.1 3.4 12.3 0.3 16.7 0.0 3.3 21.2 9.2 0.6 19.2 0.6 0.0 0.5 382.5 6.8 2.2 1.1 200.7 8.5 15.8 2.6 0.9 115.1 0.7 15.6 20.3 1.7 34.5 82.6 13.2 0.3 20.2 45.8 0.2 12.9 21.1 2.8 670.8 1.4 0.6 0.4 8.7 0.8 9.2 6.6 28.7 1.2 56.7 581.4 1.6 0.3 0.5 15.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 12.3 16.7 21.2 9.2 8.5 15.8 15.6 20.3 20.2 8.7 28.7 15.5 1.5 109.0 177.3 15.3 2.2 1.9 1.0 0.1 0.0 10.2 5.7 4.7 144.7 0.0 7.4 1.8 2.1 0.8 1.4 0.3 3.9 0.0 34.8 1.7 2.0 2.4 0.0 0.0 10.0 9.3 0.2 10.1 2.0 7.0 7.6 0.4 3.9 0.7 1.2 10.1 9.6 0.3 2.0 0.0 0.8 28.4 3.4 1.4 1.8 6.5 0.1 198.7 5.2 6.6 0.9 0.3 0.1 10.9 1.5 23.8 0.5 5.9 2.9 8.6 0.0 25.2 2.1 14.8 1.2 0.0 0.9 0.0 1.6 1.1 0.3 1.0 PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 376.2;brain: 164.1;testis: 129.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 758.4;Leydig cells: 1137.9;Peritubular cells: 225.7;Spermatocytes: 274.1" "Cancer enhanced" "Detected in many" "lung cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.3;ASC TERT1: 8.6;BJ: 7.7;THP-1: 7.7" "Region enriched" "Detected in all" 7 "basal ganglia: 3626.9" "Region enriched" "Detected in all" 7 "basal ganglia: 923.2" "HPA013138, CAB016390" Enhanced "Secreted in other tissues" NA NA 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB016390: AB_2161515, HPA013138: AB_1855191" "unprognostic (6.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.17e-3)" "unprognostic (1.56e-2)" "unprognostic (3.58e-3)" "unprognostic (1.31e-2)" "unprognostic (3.60e-1)" "unprognostic (6.34e-2)" "unprognostic (5.73e-2)" "unprognostic (3.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.98e-3)" 8.6 376.2 29.9 4.4 164.1 0.0 4.9 45.2 45.6 9.2 0.5 23.1 1.1 8.1 0.0 1.4 7.6 12.5 25.6 2.7 74.0 0.2 0.2 3.7 0.1 81.4 15.9 29.7 1.1 0.0 17.1 2.9 51.3 22.4 2.0 0.6 2.7 23.4 3.0 0.8 4.2 4.6 54.0 0.1 10.0 129.0 38.0 0.2 1.0 5.3 0.1 0.6 6.2 10.1 0.0 0.0 0.1 0.0 14.3 8.6 0.0 7.7 2.5 1.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.9 164.1 45.2 45.6 2.7 74.0 81.4 15.9 51.3 54.0 38.0 10.1 0.2 0.0 1.5 0.3 0.5 0.1 0.2 758.4 0.0 0.3 0.1 0.6 0.8 0.0 8.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 85.7 0.1 3.1 0.9 0.0 0.0 0.4 0.0 0.1 16.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.4 0.0 2.0 0.0 0.7 60.8 1137.9 1.2 0.0 1.9 0.0 0.0 0.0 0.5 0.4 0.0 0.0 225.7 0.0 0.2 0.0 0.0 3.6 0.0 6.6 1.7 1.2 274.1 19.1 0.1 0.4 0.0 0.2 3.1 0.0 0.0 PF4 "CXCL4, SCYB4" ENSG00000163737 "Platelet factor 4" P02776 4 73980811-73982027 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 66.5;lymphoid tissue: 31.5" "Cell type enriched" "Detected in some" 23 "Macrophages: 1360.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.4" "Region enriched" "Detected in single" 5 "cerebral cortex: 2.2" "Group enriched" "Detected in many" 12 "basophil: 85.2;neutrophil: 43.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 85.2" "Cell line enriched" "Detected in some" 10 "HEL: 29.8" "CAB026008, HPA052485" Enhanced "Secreted to blood" NA NA 7700000 "Cluster 34: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "CAB026008: , HPA052485: AB_2681847" "unprognostic (4.14e-4)" "unprognostic (1.00e-2)" "unprognostic (2.49e-1)" "unprognostic (1.96e-4)" "unprognostic (7.58e-2)" "unprognostic (1.42e-1)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (9.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.03e-2)" "unprognostic (9.54e-5)" "unprognostic (2.55e-1)" "unprognostic (8.77e-2)" "unprognostic (9.69e-2)" "unprognostic (4.81e-2)" 0.8 0.2 0.1 0.7 0.3 66.5 0.3 0.1 2.2 0.1 0.7 1.0 0.0 0.1 0.0 0.1 0.3 0.7 0.9 0.1 0.1 0.6 2.2 10.5 0.3 0.3 0.2 0.1 0.3 0.0 0.3 3.0 0.3 0.1 0.8 0.0 0.4 0.1 1.0 0.0 0.2 0.1 0.4 31.5 0.9 0.1 0.2 0.0 0.6 2.5 0.0 0.1 0.1 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 29.8 0.0 0.0 1.5 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.2 3.8 1.4 0.8 1.2 0.8 0.0 0.2 0.0 1.5 0.7 0.7 0.3 43.0 0.1 3.9 5.4 0.6 148.4 0.1 0.3 0.1 2.2 0.1 0.1 0.3 0.2 0.3 0.4 0.2 0.3 0.7 0.0 0.0 0.0 10.8 0.0 0.2 0.4 0.0 0.0 0.1 0.3 0.0 2.8 1.5 1.8 0.0 0.0 4.1 5.3 0.0 6.0 0.0 0.0 0.0 7.1 13.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 24.7 0.2 0.3 0.0 0.0 1.8 0.0 9.5 0.0 0.1 0.0 1360.7 0.0 0.0 59.0 0.0 57.7 0.0 0.0 7.6 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.4 0.0 0.0 0.3 5.8 0.0 7.4 0.2 PF4V1 "CXCL4L1, CXCL4V1, SCYB4V1" ENSG00000109272 "Platelet factor 4 variant 1" P10720 4 73853296-73854483 "Plasma proteins, Predicted secreted proteins" "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7;lymphoid tissue: 2.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 10.0;Club cells: 2.6;Enteroendocrine cells: 5.3;Macrophages: 6.4;Theca cells: 2.2" "Cancer enhanced" "Detected in some" "renal cancer: 3.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 38 "basophil: 14.2;neutrophil: 9.9" "Lineage enriched" "Detected in single" 45 "granulocytes: 14.2" "Cell line enhanced" "Detected in single" "EFO-21: 1.7" HPA052485 Supported "Secreted to blood" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA052485: AB_2681847" "unprognostic (4.95e-1)" "unprognostic (5.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-3)" "unprognostic (9.88e-2)" "unprognostic (1.72e-2)" "unprognostic (1.68e-3)" "unprognostic (2.66e-1)" "unprognostic (6.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.95e-3)" "unprognostic (1.39e-2)" "unprognostic (2.11e-1)" 0.2 0.0 0.0 0.1 0.2 1.2 0.2 0.0 0.3 0.2 0.1 0.1 1.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.7 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.4 1.1 0.0 0.0 0.9 0.0 0.0 2.4 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.1 0.3 0.0 11.2 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.1 0.0 10.0 2.6 1.8 0.0 0.0 0.0 0.1 1.9 0.3 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.7 2.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 6.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 1.4 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.5 PGA3 ENSG00000229859 "Pepsinogen A3" P0DJD8 11 61203307-61213098 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 613 "stomach 1: 89073.4" "Cell type enriched" "Detected in some" 526 "Gastric mucus-secreting cells: 3263.5" "Cancer enriched" "Detected in single" 498 "stomach cancer: 24.8" "Region enhanced" "Detected in single" "hippocampal formation: 2.9" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 2.8;THP-1: 1.1" "CAB026358, HPA046875" Enhanced "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB026358: , HPA046875: AB_2679851" "unprognostic (6.39e-2)" "unprognostic (1.11e-1)" 80.5 10.0 0.5 0.2 0.2 0.2 18.2 0.7 0.9 11.1 0.0 145.3 1.3 3.8 0.0 96.4 4.5 0.1 11.4 2.9 0.0 5.4 16.2 6.2 0.0 0.0 0.0 5.4 13.0 0.0 13.4 0.5 0.1 5.5 0.1 0.9 6.8 0.7 4.4 6.0 5.7 0.4 0.0 6.3 89073.4 7.3 0.0 0.1 5.0 0.5 0.1 6.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.1 0.7 1.3 0.4 0.1 0.2 0.7 0.1 0.1 0.1 0.6 0.4 0.2 0.3 0.0 0.0 1.3 0.5 0.2 0.7 0.9 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 6.2 0.0 0.3 3263.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.1 0.0 3.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.1 PGA4 ENSG00000229183 "Pepsinogen A4" P0DJD7 11 61222349-61231694 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1281 "stomach 1: 66596.4" "Cell type enriched" "Detected in some" 8 "Exocrine glandular cells: 109.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "classical monocyte: 9.9;intermediate monocyte: 10.9;non-classical monocyte: 3.4" "Lineage enriched" "Detected in single" 26 "monocytes: 10.9" "Group enriched" "Detected in some" 6 "BJ hTERT+: 26.1;HMC-1: 9.5;THP-1: 15.7" HPA046875 Supported "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "HPA046875: AB_2679851" "unprognostic (2.22e-1)" 9.6 8.3 0.1 2.1 0.1 0.0 9.0 0.1 0.2 7.5 0.1 52.0 2.5 4.6 0.0 9.1 19.1 0.3 6.2 0.1 0.1 30.3 11.7 37.9 0.0 0.1 0.1 4.1 18.8 0.0 3.5 3.8 0.1 16.2 0.4 0.3 4.5 0.7 2.5 4.1 2.9 0.8 0.1 5.2 66596.4 4.3 0.1 0.1 3.1 0.0 0.2 5.0 5.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.0 0.0 1.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 1.1 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.0 3.4 0.0 0.0 1.8 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 109.1 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGA5 ENSG00000256713 "Pepsinogen A5" P0DJD9 11 61241175-61251444 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2014 "stomach 1: 39870.8" "Cell type enriched" "Detected in some" 77 "Exocrine glandular cells: 4383.1" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 29 "classical monocyte: 1.8;intermediate monocyte: 4.3;non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 44 "monocytes: 4.3" "Cell line enriched" "Detected in some" 19 "BJ hTERT+: 28.8" HPA046875 Supported "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA046875: AB_2679851" "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" 19.7 4.4 0.3 1.1 0.3 0.0 4.5 0.1 0.6 4.0 0.0 6.2 0.6 1.9 0.0 7.0 5.1 0.1 3.5 0.7 0.0 2.4 7.0 5.4 0.0 0.1 0.0 2.6 8.2 0.0 3.8 0.5 0.1 1.8 0.1 1.5 2.5 0.5 1.9 2.1 2.1 0.9 0.0 3.9 39870.8 2.3 0.0 0.2 3.1 0.2 0.1 2.3 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.3 0.3 0.3 0.1 0.6 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 4383.1 0.0 0.1 56.6 0.0 0.0 0.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 5.1 0.0 1.6 0.9 1.3 0.0 0.0 1.0 25.1 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "stomach 1: 59821.1" "Group enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 5737.5;Pancreatic endocrine cells: 1449.1" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 253.1;OE19: 152.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" 19.4 7.0 0.0 0.3 0.1 0.2 6.6 1.2 0.5 6.7 0.0 26.4 1327.3 2.8 0.9 85.5 9.2 2.3 6.2 0.1 0.0 4.9 11.0 378.8 0.3 0.0 0.0 3.9 136.3 0.0 7.4 2.8 0.0 83.9 0.3 0.1 4.6 437.7 2.5 3.4 3.2 0.0 0.0 7.7 59821.1 4.2 0.0 0.1 2.2 0.0 0.3 3.8 4.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.1 0.0 0.0 18.4 0.0 0.0 0.6 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 253.1 0.0 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.9 5.7 152.2 0.0 2.9 0.0 6.2 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.8 0.0 0.0 3.7 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.6 335.2 0.0 4.4 0.4 2.8 0.0 0.0 0.0 0.3 0.8 0.3 87.2 5.0 0.0 0.0 1.2 0.0 0.3 0.0 4.6 0.0 0.4 0.0 1.1 0.0 0.0 0.3 131.2 1.5 0.9 5737.5 0.1 10.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 1.7 0.0 0.0 2.0 0.0 0.0 0.0 0.1 1449.1 2.1 0.0 2.4 85.2 0.1 0.2 3.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 4.1 2.6 0.0 0.2 4.2 PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 50.5;thyroid gland: 52.5" "Group enriched" "Detected in many" 11 "Extravillous trophoblasts: 1604.4;Syncytiotrophoblasts: 2122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "BEWO: 422.4;HUVEC TERT2: 199.1" "Low region specificity" "Detected in all" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" No No 20800 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Mitochondria, Cytosol" "HPA041624: AB_10794522" "unprognostic (1.67e-2)" "unprognostic (4.62e-2)" "unprognostic (9.25e-3)" "unprognostic (1.34e-3)" "unprognostic (8.67e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (4.45e-1)" "unprognostic (1.45e-2)" "unprognostic (3.51e-3)" "prognostic unfavorable (1.33e-6)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (1.14e-1)" 11.8 4.9 7.4 7.8 7.6 0.1 11.3 7.3 11.7 22.4 20.2 7.0 2.4 7.6 1.4 10.0 21.8 5.9 18.8 8.7 20.6 8.1 6.0 7.2 6.4 9.5 15.7 6.4 4.9 8.4 5.5 50.5 9.3 19.3 2.0 1.2 10.5 10.3 9.9 15.7 12.5 7.8 7.0 3.3 4.8 3.2 8.6 3.9 52.5 5.9 3.3 13.6 14.8 7.8 1.4 1.5 1.3 1.3 2.0 0.2 422.4 4.0 3.6 1.8 2.2 10.9 0.6 0.3 9.1 2.8 0.2 0.5 1.8 19.2 1.6 0.2 2.4 0.0 0.1 11.3 1.5 0.2 11.0 4.7 4.5 7.5 1.8 0.5 199.1 0.0 0.0 0.1 55.6 0.9 0.0 0.5 2.1 0.1 3.4 0.2 51.3 0.0 0.5 1.0 31.0 17.0 0.0 0.8 7.7 25.0 0.1 0.5 40.6 0.3 10.2 0.1 17.0 0.4 0.2 0.7 6.3 0.5 0.5 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 7.4 7.6 7.3 11.7 8.7 20.6 9.5 15.7 9.3 7.0 8.6 7.8 32.4 9.6 4.6 1.0 1.0 24.6 10.3 111.4 34.7 1.3 8.9 16.0 3.6 0.0 26.0 0.0 14.6 83.8 2.4 2.0 0.0 2.7 0.1 1.1 3.3 169.4 7.1 2.7 0.1 0.5 1604.4 30.8 1.1 0.8 6.3 0.2 5.3 0.3 37.4 0.0 0.2 2.1 18.3 0.6 8.9 0.8 13.1 2.1 21.4 0.0 0.0 1.9 0.0 0.0 0.2 0.5 1.2 19.5 0.2 3.2 0.6 1.1 12.1 7.8 105.2 7.1 86.4 0.2 6.8 8.1 19.6 2122.6 3.0 3.0 2.3 5.8 PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 629.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Excitatory neurons: 1.7;Inhibitory neurons: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.4" "Group enriched" "Detected in some" 202 "eosinophil: 443.7;neutrophil: 494.6" "Lineage enriched" "Detected in many" 213 "granulocytes: 494.6" "Cell line enhanced" "Detected in some" "A549: 3.1;HEK 293: 1.8;HeLa: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 35000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" 1.5 0.3 0.3 1.8 1.1 629.4 0.3 3.4 1.5 0.1 0.0 0.3 0.6 0.2 0.0 0.5 0.6 0.2 1.7 0.6 0.0 0.8 2.5 8.7 0.5 0.0 0.1 0.1 0.5 0.0 0.7 0.9 0.0 0.2 0.0 0.0 0.5 0.0 0.3 1.0 0.7 0.1 0.0 42.5 0.4 1.0 0.0 3.3 0.5 2.3 0.0 0.4 0.2 0.0 0.3 3.1 0.5 0.3 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.5 0.2 0.8 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.8 1.8 0.3 1.7 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.3 0.0 0.2 0.2 0.9 0.2 0.0 1.2 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.7 0.6 0.3 0.4 0.7 0.0 0.2 0.4 443.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 494.6 0.0 2.3 0.0 0.1 3.9 0.3 1.1 3.4 1.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 258.8" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 168.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 5 "MCF7: 8.1;T-47d: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" NA NA 87000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 2: Hepatocytes - Metabolism" "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 258.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.4 0.4 0.2 1.6 1.7 1.6 0.2 0.9 0.8 0.1 0.0 2.2 2.3 1.6 0.5 5.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.2 0.5 0.0 0.0 4.1 1.5 0.2 4.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.9 168.7 0.3 0.0 0.4 0.0 0.0 2.2 0.0 3.1 0.3 1.9 8.8 0.0 1.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 14.1 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.0 7.6 0.0 0.0 0.1 PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 38.9;skin 1: 73.7;vagina: 21.4" "Cell type enriched" "Detected in single" 12 "Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;head and neck cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "HaCaT: 3.8;HDLM-2: 1.6;hTCEpi: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 73.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 7.6 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.5;esophagus: 8.2;skin 1: 15.1;vagina: 10.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 30.1;Club cells: 9.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.7;HDLM-2: 2.2;Karpas-707: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 2.3 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 30.1 0.6 0.0 0.0 0.1 0.3 0.0 9.7 0.0 0.0 0.0 0.0 0.1 0.0 1.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 0.3 0.3 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 4.0 3.4 0.3 0.0 0.0 0.2 0.2 PI15 P25TI ENSG00000137558 "Peptidase inhibitor 15" O43692 8 74824534-74855029 "Predicted secreted proteins" "Developmental protein, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.4;prostate: 31.0;smooth muscle: 49.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.8;Breast glandular cells: 73.2;Breast myoepithelial cells: 13.6;Prostatic glandular cells: 19.3;Smooth muscle cells: 36.2;Urothelial cells: 15.7" "Group enriched" "Detected in many" 7 "breast cancer: 11.1;melanoma: 8.6;prostate cancer: 18.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 23.3;SH-SY5Y: 21.3;SK-MEL-30: 30.0;U-266/70: 7.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 6.3" "HPA006593, HPA030057" Uncertain Approved Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" Vesicles Cytosol "HPA006593: AB_1078568, HPA030057: AB_10602143" "unprognostic (2.77e-1)" "unprognostic (1.57e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (2.94e-2)" "unprognostic (2.33e-3)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (3.65e-2)" "unprognostic (1.85e-2)" "unprognostic (8.63e-14)" "unprognostic (2.54e-3)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" 5.8 1.1 0.6 54.4 0.8 0.0 22.1 0.1 1.6 11.0 0.0 7.8 0.2 19.8 2.1 2.5 20.9 1.5 1.8 0.9 0.9 0.9 0.2 2.2 0.6 0.7 0.8 6.3 0.3 0.0 0.5 0.3 0.4 31.0 4.6 0.6 2.0 6.8 0.4 0.4 4.6 49.9 1.1 1.3 0.7 0.5 2.4 0.4 0.6 0.2 0.2 8.3 6.5 0.6 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.1 21.3 0.0 0.1 30.0 0.4 0.5 0.5 0.0 0.0 0.5 0.0 0.1 7.9 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.1 1.6 0.9 0.9 0.7 0.8 0.4 1.1 2.4 0.6 0.2 0.0 0.0 2.3 0.1 0.1 36.8 0.0 0.6 0.2 73.2 13.6 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 1.6 0.2 9.1 2.5 0.0 0.0 4.3 0.0 0.4 3.9 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.6 1.9 0.9 0.2 3.6 1.0 0.0 0.0 0.0 0.5 2.0 0.0 0.0 0.0 0.1 19.3 0.0 0.1 0.0 0.5 0.0 1.7 36.2 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.0 15.7 PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 204.8;Leydig cells: 205.9;Oligodendrocytes: 67.3;Peritubular cells: 149.7" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cell line enriched" "Detected in some" 6 "JURKAT: 29.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" 57.8 3.5 12.2 3.1 17.7 0.2 66.1 14.3 15.1 140.6 7.9 11.6 1.5 5.7 29.0 10.6 15.0 46.4 127.7 10.1 16.1 1.5 0.7 11.4 2.2 15.3 14.2 3.4 5.6 0.9 8.4 2.4 15.8 31.3 7.9 0.0 14.0 34.2 15.1 51.7 4.5 8.4 13.4 1.3 22.1 14.7 16.4 2.4 23.2 33.6 6.0 116.1 127.6 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.9 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 29.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.8 0.6 19.7 5.7 0.0 1.3 6.4 2.2 0.5 13.5 0.0 0.5 66.1 3.3 12.2 17.7 14.3 15.1 10.1 16.1 15.3 14.2 15.8 13.4 16.4 19.3 10.9 0.0 1.5 3.3 0.7 21.5 0.1 0.0 0.6 0.0 0.4 0.4 4.5 0.0 0.6 1.8 0.0 0.0 0.4 0.0 1.9 0.1 10.8 0.1 0.2 11.0 0.0 0.0 0.1 0.0 0.0 204.8 4.1 0.1 0.0 0.0 10.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 39.6 19.0 205.9 1.9 10.6 3.7 0.0 0.0 0.0 0.0 67.3 0.1 0.0 149.7 0.6 0.1 0.0 0.2 0.0 0.0 0.0 7.7 4.2 2.4 1.3 0.4 18.5 0.1 3.5 0.3 0.0 0.2 PI3 "cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14" ENSG00000124102 "Peptidase inhibitor 3" P19957 20 45174902-45176544 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2267.8;lymphoid tissue: 2103.1;vagina: 1595.8" "Group enriched" "Detected in many" 10 "Basal respiratory cells: 5354.5;Club cells: 2170.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 2666.5" "Group enriched" "Detected in some" 22 "cerebral cortex: 12.0;pons: 7.3;thalamus: 19.0" "Immune cell enriched" "Detected in some" 1021 "neutrophil: 1763.3" "Lineage enriched" "Detected in single" 4377 "granulocytes: 1763.3" "Group enriched" "Detected in many" 5 "EFO-21: 89.3;HaCaT: 109.8;OE19: 103.7;PC-3: 189.9" "CAB009449, HPA017737" Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 1400000 "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB009449: AB_2252354, HPA017737: AB_1848107" "prognostic favorable (6.94e-4)" "unprognostic (3.61e-2)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (7.34e-2)" "unprognostic (1.85e-1)" "unprognostic (3.20e-3)" "unprognostic (5.53e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.84e-6)" "prognostic unfavorable (6.89e-4)" "unprognostic (8.54e-3)" "prognostic unfavorable (1.94e-8)" "unprognostic (1.23e-1)" "unprognostic (7.38e-2)" "unprognostic (1.04e-2)" "unprognostic (5.91e-3)" 6.1 0.7 0.2 101.9 0.5 1.8 8.8 0.2 12.0 180.1 1.2 124.3 1.9 2.3 1.1 2267.8 4.8 56.6 1.7 0.2 0.4 1.5 3.3 32.5 0.4 0.3 0.3 0.7 1.6 0.2 2.8 1.1 7.3 11.7 43.3 0.0 460.8 3.5 0.6 78.6 42.3 7.5 0.3 20.0 9.0 0.5 19.0 90.6 0.8 1.9 2103.1 44.7 1595.8 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.4 0.0 3.1 2.1 1.4 89.3 0.0 1.1 109.8 0.0 23.2 0.1 1.2 0.0 0.5 6.3 0.9 0.0 0.7 0.0 0.0 21.7 17.8 1.9 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.1 0.2 103.7 189.9 0.0 1.0 0.0 21.9 0.4 0.0 0.0 15.7 2.1 0.1 0.0 0.0 0.0 0.8 1.0 10.9 0.3 0.9 0.3 1.8 0.4 14.3 0.7 0.1 0.3 0.4 1.7 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 1763.3 0.0 0.1 0.1 0.1 0.6 0.2 0.5 0.2 12.0 0.2 0.4 0.3 0.3 7.3 0.3 19.0 0.3 0.1 0.0 8.6 0.0 7.4 0.1 4.7 5354.5 0.0 0.0 39.4 8.4 0.2 8.6 2170.2 18.4 0.0 0.2 0.5 375.4 0.0 46.6 0.1 3.7 0.7 3.0 16.6 0.0 0.0 317.3 0.0 0.8 2.6 6.9 4.5 0.0 0.0 0.0 0.1 0.0 0.0 31.8 197.4 0.0 0.4 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.8 219.6 0.0 0.2 29.1 33.9 0.2 152.9 0.0 0.0 0.0 50.5 0.0 0.0 36.2 3.8 0.0 2.5 0.1 154.1 150.4 PIBF1 "C13orf24, CEP90" ENSG00000083535 "Progesterone immunomodulatory binding factor 1" Q8WXW3 13 72782133-73016461 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 334.5;Oligodendrocyte precursor cells: 143.7;Oligodendrocytes: 138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052269, HPA066120" Approved Supported "Centriolar satellite" "Secreted to blood" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Centriolar satellite" "HPA052269: AB_2681779, HPA066120: AB_2685621" "unprognostic (1.54e-1)" "unprognostic (4.17e-1)" "unprognostic (6.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (3.80e-2)" "unprognostic (3.79e-2)" "unprognostic (3.87e-2)" "unprognostic (4.08e-2)" "unprognostic (2.62e-2)" "unprognostic (2.26e-3)" "unprognostic (1.39e-1)" "unprognostic (6.85e-3)" "unprognostic (8.31e-2)" "unprognostic (2.78e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-1)" 7.6 9.1 5.2 6.7 5.5 10.2 12.2 7.4 7.3 11.5 9.8 7.4 7.0 11.5 10.7 7.1 11.0 8.4 7.5 4.6 4.8 8.3 9.8 8.7 9.9 5.1 5.0 12.6 5.5 8.5 7.5 9.7 4.7 9.8 8.8 10.2 7.4 8.2 6.6 8.5 6.9 8.5 4.7 8.4 8.7 14.3 5.0 13.0 15.5 7.4 8.4 10.1 8.0 6.0 13.1 4.2 16.8 9.8 14.4 25.3 6.5 11.9 15.9 11.8 14.4 5.8 22.1 12.0 13.7 13.2 6.2 11.1 9.1 12.0 18.9 12.2 8.7 8.2 10.9 6.7 18.4 31.0 7.5 16.4 9.4 12.7 30.7 15.1 15.5 8.2 11.7 6.1 15.9 3.7 15.2 18.6 8.9 23.3 3.9 12.0 12.4 12.4 24.5 7.0 9.6 15.4 9.2 6.3 16.3 13.5 10.6 21.8 11.8 6.0 6.3 9.5 7.2 9.7 7.5 6.0 18.0 17.3 13.3 8.4 3.4 6.1 6.0 3.7 6.4 5.9 6.4 6.5 3.0 5.6 8.7 7.3 3.3 8.6 3.6 5.1 5.3 2.5 5.2 5.5 7.4 7.3 4.6 4.8 5.1 5.0 4.7 4.7 5.0 6.0 33.8 32.1 30.8 101.2 21.6 10.3 16.3 10.5 16.5 17.1 15.5 17.8 28.1 14.3 27.7 5.5 16.7 9.4 19.3 6.6 13.7 11.6 334.5 41.5 33.6 20.0 7.2 15.2 115.1 11.1 10.2 20.4 21.4 18.5 24.1 21.8 9.7 5.6 7.1 18.5 119.3 9.7 12.2 8.6 3.5 50.4 19.3 10.3 8.8 92.8 9.8 11.9 17.5 143.7 138.6 12.0 8.5 15.4 11.6 11.8 7.1 6.5 46.3 31.3 13.1 28.9 17.9 59.4 39.2 11.8 8.9 6.0 23.1 25.6 10.0 13.7 PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2641.0;salivary gland: 1645.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7090.1;Intestinal goblet cells: 2361.1;Paneth cells: 3208.3;Proximal enterocytes: 1558.6;Undifferentiated cells: 4954.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "EFO-21: 36.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" NA NA 1300000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" 2.4 0.5 0.4 187.3 0.2 0.3 131.0 0.5 0.4 547.0 0.2 1693.4 2641.0 20.5 0.2 12.4 3.6 455.0 0.5 0.4 0.2 108.9 34.5 101.6 1.7 0.2 0.2 0.6 13.3 0.1 1.3 0.3 0.4 13.6 1222.6 0.1 1645.1 5.3 0.3 0.6 809.8 39.1 0.1 0.8 414.6 0.3 0.6 0.4 0.2 0.0 0.6 80.3 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 36.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 1.9 0.3 0.0 0.0 0.2 0.0 6.9 0.2 1.7 0.8 2.5 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.3 0.6 0.3 0.4 1.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.3 0.8 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.4 0.2 0.5 0.4 0.4 0.2 0.2 0.2 0.4 0.1 0.6 0.6 2.1 93.0 604.3 0.0 22.1 0.3 4.0 106.6 0.0 0.0 392.4 192.0 1.4 876.4 638.4 108.5 0.0 0.1 2.5 7090.1 17.6 92.5 0.0 65.9 14.6 5.4 426.4 2.7 0.0 64.5 0.0 4.7 482.1 120.1 52.0 0.0 1.8 28.0 0.4 0.0 0.0 2361.1 59.0 2.2 1.1 0.0 0.0 5.7 1.8 0.0 0.6 0.0 0.0 0.0 0.0 221.5 3208.3 0.0 0.7 53.9 1558.6 328.4 415.4 0.0 0.0 0.0 21.0 0.0 0.0 6.9 0.0 0.0 15.6 0.1 4954.6 761.3 PILRA FDF03 ENSG00000085514 "Paired immunoglobin like type 2 receptor alpha" Q9UKJ1 7 100367530-100400096 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 80.8;Kupffer cells: 100.7;Langerhans cells: 65.9;Leydig cells: 52.5;Macrophages: 144.7;monocytes: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1659.8;non-classical monocyte: 1146.1" "Group enriched" "Detected in all" 5 "granulocytes: 1659.8;monocytes: 1146.1" "Cell line enhanced" "Detected in some" "ASC diff: 27.9;HMC-1: 25.5;NB-4: 20.4" HPA056132 Approved "Secreted to blood" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056132: AB_2683048" "unprognostic (5.53e-2)" "prognostic favorable (2.99e-4)" "unprognostic (7.61e-2)" "unprognostic (2.88e-1)" "unprognostic (2.20e-1)" "unprognostic (5.88e-2)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (3.01e-3)" "unprognostic (9.95e-2)" "unprognostic (8.57e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.47e-2)" "unprognostic (3.17e-2)" "unprognostic (1.99e-1)" "unprognostic (4.80e-2)" 14.6 9.3 7.2 38.5 7.5 26.0 8.9 13.7 9.6 10.7 7.7 7.6 4.1 8.2 4.7 3.7 14.2 9.3 5.7 6.9 9.3 12.6 9.7 30.4 9.2 12.1 9.4 9.5 5.3 3.6 15.5 11.3 11.7 11.3 5.3 3.8 5.7 4.0 5.3 5.3 8.0 9.8 9.0 31.1 5.9 10.8 9.3 5.0 9.4 2.9 3.5 17.7 6.7 15.5 0.3 0.4 0.6 0.7 27.9 1.8 0.2 0.2 1.4 0.1 0.5 0.0 0.5 0.6 1.7 0.4 0.3 0.8 0.2 0.1 0.0 1.4 1.0 0.6 1.3 0.1 0.3 1.1 25.5 2.0 0.4 0.2 0.6 0.1 0.3 2.5 0.2 1.8 0.2 0.9 2.0 20.4 0.6 0.4 0.3 0.5 0.0 0.4 1.1 0.6 0.8 0.3 0.0 6.9 0.7 0.1 0.1 6.0 0.6 1.2 1.2 0.8 0.2 2.5 2.0 0.6 0.3 2.3 0.4 316.9 584.3 18.5 2.5 863.0 2.1 2.3 0.9 1.0 288.0 1.1 1.0 1.8 1659.8 6.4 1146.1 5.4 2.2 354.1 7.2 7.5 13.7 9.6 6.9 9.3 12.1 9.4 11.7 9.0 9.3 15.5 1.0 3.2 12.4 8.8 2.7 1.8 0.3 0.9 0.0 3.6 2.1 3.0 0.6 2.8 3.9 1.8 4.2 0.6 2.1 0.6 27.4 0.2 0.7 3.9 13.1 4.1 0.0 2.7 15.9 0.4 0.6 2.8 0.5 5.8 10.1 0.8 1.8 1.8 80.8 1.7 14.8 1.3 0.0 100.7 65.9 1.9 52.5 144.7 1.8 28.1 72.3 1.4 3.1 2.0 10.3 0.3 0.1 21.4 0.4 0.5 0.1 0.7 3.1 2.4 0.0 1.0 0.7 1.6 2.6 0.2 0.9 0.8 2.0 0.4 0.9 0.3 PINLYP ENSG00000234465 "Phospholipase A2 inhibitor and LY6/PLAUR domain containing" A6NC86 19 43575801-43583964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 23.5;Proximal tubular cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 73.1;HMC-1: 46.6;JURKAT: 37.1;REH: 29.8;THP-1: 36.6" "Not detected" "Not detected" HPA061218 Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA061218: AB_2684453" "unprognostic (6.72e-2)" "unprognostic (6.21e-2)" "unprognostic (4.72e-1)" "unprognostic (3.13e-2)" "unprognostic (2.46e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" "unprognostic (5.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.85e-2)" "unprognostic (1.14e-1)" "unprognostic (4.36e-3)" "unprognostic (1.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-2)" 9.9 3.5 16.3 3.3 16.7 2.7 8.5 18.1 22.1 17.3 16.1 13.3 1.4 14.7 9.4 10.5 17.1 9.3 9.8 16.1 16.8 22.9 2.1 7.7 5.0 17.2 17.0 19.6 2.4 0.7 14.9 2.8 16.0 13.5 3.0 2.6 5.8 10.4 1.7 7.6 6.4 11.1 16.4 8.4 7.3 5.4 17.4 10.6 11.8 3.3 5.2 10.3 13.0 15.7 0.7 0.3 1.9 0.3 3.4 4.5 0.4 0.8 1.2 1.6 4.3 0.0 0.1 0.0 0.2 19.0 1.8 4.0 0.0 0.2 1.5 0.1 0.2 73.1 0.8 0.1 10.3 0.0 46.6 10.2 0.4 10.3 0.2 4.3 2.7 37.1 0.9 1.0 0.7 0.4 8.9 1.1 1.8 0.1 0.7 29.8 0.2 0.0 0.8 0.4 0.3 0.0 0.0 0.4 0.1 0.3 0.1 36.6 1.2 4.7 0.9 0.1 3.1 0.0 0.0 4.4 16.0 0.0 0.4 10.4 1.5 0.7 3.0 1.2 3.6 1.7 0.9 2.5 2.3 4.7 0.3 3.6 0.5 1.4 0.2 21.0 2.0 1.7 16.3 16.7 18.1 22.1 16.1 16.8 17.2 17.0 16.0 16.4 17.4 15.7 1.8 12.8 3.2 2.3 1.1 3.6 10.0 5.6 8.6 6.1 2.4 5.6 2.8 8.6 5.7 9.2 6.2 0.4 1.8 0.1 23.5 1.3 6.4 2.1 9.9 4.3 0.0 4.4 0.5 0.4 0.4 9.1 2.0 2.0 0.0 7.6 5.7 0.0 5.1 6.7 1.1 0.8 2.0 1.0 3.9 7.3 11.5 2.7 5.4 1.9 3.3 5.6 0.0 5.0 0.5 0.4 0.1 9.8 1.7 5.2 0.7 19.0 15.0 3.3 0.0 2.1 5.9 2.3 1.2 6.7 3.1 0.1 1.2 13.6 1.7 6.6 PIP "GCDFP-15, GCDFP15, GPIP4" ENSG00000159763 "Prolactin induced protein" P12273 7 143132077-143139739 "Plasma proteins, Predicted secreted proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 16791.8" "Group enriched" "Detected in many" 4 "Breast glandular cells: 1117.6;Breast myoepithelial cells: 324.2;Melanocytes: 403.8" "Cancer enriched" "Detected in many" 70 "breast cancer: 672.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 333 "T-47d: 703.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB002661, HPA009177" Enhanced "Secreted in other tissues" NA NA 66000000 "Cluster 37: B-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "CAB002661: , HPA009177: AB_1845459" "unprognostic (2.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-3)" "unprognostic (3.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.14e-1)" "unprognostic (3.49e-2)" "unprognostic (5.55e-1)" 9.1 3.6 0.7 0.2 4.8 0.1 3458.7 2.7 2.7 5.6 0.0 0.5 0.0 0.1 2.7 1.3 4.2 0.1 4.8 0.9 4.6 0.5 2.0 6.4 0.8 8.5 4.4 3.8 21.1 0.4 1.9 2.3 6.8 33.3 0.0 0.0 16791.8 3140.5 1.7 189.7 0.6 0.0 3.5 0.6 0.6 0.7 4.6 0.3 0.7 0.0 1.8 0.6 1.5 11.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 1.3 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 703.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.8 2.7 2.7 0.9 4.6 8.5 4.4 6.8 3.5 4.6 11.5 6.9 0.0 2.0 0.0 3.6 10.8 6.6 18.8 0.0 0.0 1117.6 324.2 0.1 0.0 48.2 1.8 0.0 0.0 7.0 0.0 0.0 9.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 2.5 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.4 0.0 1.6 0.0 0.0 1.5 403.8 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 0.0 13.1 0.0 0.1 147.1 0.0 0.0 0.0 9.2 0.0 0.0 0.0 1.7 0.0 2.5 0.0 0.0 13.7 PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048021-42058517 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 85.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 71.9;Fibroblasts: 55.4;Leydig cells: 137.6;Peritubular cells: 112.1;Rod photoreceptor cells: 95.9;Theca cells: 135.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 85.9;ASC diff: 61.7;CACO-2: 101.0;HHSteC: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" NA NA 80000 "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA026427: AB_10600773, HPA026442: AB_10601237, HPA026526: AB_10602416" "unprognostic (6.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.59e-3)" "unprognostic (8.31e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (5.79e-3)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.08e-2)" "unprognostic (2.62e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-3)" 25.7 11.3 3.1 4.9 3.8 0.8 16.1 0.8 6.2 31.8 6.4 20.3 10.7 25.7 2.1 2.2 24.2 3.3 37.6 4.8 1.0 10.7 6.9 16.5 2.1 1.5 1.6 50.1 7.0 1.1 6.8 3.6 1.3 12.2 5.7 5.3 20.7 5.8 85.5 3.8 13.7 9.8 1.4 9.6 9.6 14.8 2.1 6.4 5.1 27.7 1.4 32.5 17.4 4.7 0.0 5.5 14.0 85.9 61.7 0.7 5.3 0.2 0.0 1.2 1.5 101.0 0.2 0.0 0.3 1.7 1.8 0.0 1.3 0.0 0.0 8.1 3.5 0.2 3.3 27.0 53.7 0.0 1.2 5.7 0.3 0.2 0.0 0.6 0.7 0.0 1.2 0.0 0.3 0.3 0.0 0.3 23.8 6.8 1.7 0.0 27.3 0.0 0.0 0.0 2.8 5.1 1.3 0.0 0.2 16.3 0.1 0.7 0.0 0.6 2.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.8 0.8 6.2 4.8 1.0 1.5 1.6 1.3 1.4 2.1 4.7 28.8 19.2 0.5 4.2 0.3 3.2 0.2 0.0 0.0 4.7 1.3 2.0 9.2 1.5 0.0 1.8 16.7 0.5 0.6 22.8 0.0 2.1 1.1 6.0 31.4 3.1 71.9 0.0 22.8 1.3 1.3 55.4 2.6 26.3 0.0 4.5 2.9 2.7 0.6 0.0 3.3 18.6 0.0 0.6 3.1 5.4 137.6 0.6 1.8 3.7 0.0 21.3 0.0 10.1 1.8 1.9 16.0 112.1 0.0 0.8 15.2 3.9 0.0 95.9 13.1 14.2 15.1 0.7 1.7 0.0 1.8 0.3 0.8 135.4 35.9 0.1 PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 138.4;parathyroid gland: 65.8;seminal vesicle: 67.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Endothelial cells: 14.3;Hepatocytes: 26.0;Langerhans cells: 15.6;Peritubular cells: 14.3" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "SK-MEL-30: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" NA NA 420000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" 4.9 0.7 12.1 3.5 11.3 0.3 3.4 11.6 16.3 4.7 26.8 2.7 1.1 4.7 138.4 1.5 5.7 2.8 4.9 12.5 12.0 7.7 39.6 21.2 15.6 13.2 12.3 1.1 3.7 65.8 1.7 9.8 13.2 9.1 2.5 1.0 3.5 67.2 16.2 0.8 3.5 8.8 13.4 1.0 4.4 3.7 14.7 1.6 6.9 3.1 8.7 3.9 1.9 12.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.3 0.5 0.1 0.0 0.2 0.0 0.0 25.0 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.1 11.3 11.6 16.3 12.5 12.0 13.2 12.3 13.2 13.4 14.7 12.4 6.5 0.0 1.7 0.0 0.0 0.6 0.5 0.4 0.6 0.0 0.1 0.1 2.8 2.8 1.0 14.7 0.0 0.2 0.1 0.0 1.9 4.7 6.6 0.1 0.1 14.3 1.8 0.0 0.2 2.2 0.0 1.6 0.0 0.9 1.3 0.7 7.9 26.0 1.6 0.0 0.1 0.1 0.0 1.0 15.6 3.2 0.3 5.4 1.8 4.7 4.2 0.0 0.0 0.0 0.0 1.3 0.6 14.3 0.0 0.5 0.0 5.1 7.5 0.1 0.0 0.9 5.9 0.0 0.2 0.0 0.6 1.9 0.1 0.0 0.1 0.2 PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672548-14694308 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 27.3;pancreas: 10.5;stomach 1: 41.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 280.1;Exocrine glandular cells: 116.3;Gastric mucus-secreting cells: 116.2;Intestinal goblet cells: 137.7;Paneth cells: 225.3" "Cancer enhanced" "Detected in many" "stomach cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.6;CAPAN-2: 6.4;HaCaT: 2.2;MCF7: 2.3;OE19: 5.9;SK-BR-3: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041893 Uncertain "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041893: AB_10794495" "unprognostic (8.44e-3)" "unprognostic (2.37e-1)" "unprognostic (6.72e-2)" "prognostic favorable (5.74e-5)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (5.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-2)" "unprognostic (9.97e-3)" 0.0 0.2 0.1 2.4 0.1 0.1 0.1 0.1 0.2 1.3 0.1 27.3 7.6 0.1 0.0 0.2 4.5 3.4 0.0 0.1 0.1 0.1 0.0 4.7 0.2 0.1 0.1 0.0 10.5 0.0 0.0 0.3 0.1 0.4 23.6 0.0 0.1 0.0 0.0 0.0 7.0 0.6 0.1 0.0 41.9 2.2 0.1 0.0 0.0 0.0 0.3 4.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.5 6.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 5.9 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 3.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 35.3 23.1 0.7 0.3 0.0 0.9 3.7 0.6 0.0 0.7 0.5 0.1 5.7 17.9 1.8 0.0 0.6 0.1 280.1 0.0 2.6 0.3 25.1 3.5 0.2 12.7 0.0 0.5 116.3 56.7 0.1 116.2 45.7 0.0 0.4 0.0 0.0 0.9 0.0 0.3 137.7 24.4 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 20.5 225.3 0.0 0.7 1.3 16.1 0.0 60.1 0.0 0.0 0.0 2.0 1.1 1.2 1.7 0.0 0.5 0.5 0.0 57.3 14.6 PLA2G12A PLA2G12 ENSG00000123739 "Phospholipase A2 group XIIA" Q9BZM1 4 109709989-109730070 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035908, HPA035909" Approved "Secreted to blood" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "HPA035908: AB_2674856, HPA035909: AB_10672074" "unprognostic (8.40e-2)" "unprognostic (3.87e-1)" "unprognostic (3.81e-3)" "unprognostic (3.09e-2)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (4.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.90e-1)" "unprognostic (2.71e-3)" "unprognostic (1.02e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.54e-9)" "unprognostic (3.10e-1)" "unprognostic (1.39e-1)" "unprognostic (9.16e-3)" "unprognostic (3.64e-2)" 10.0 9.0 11.4 3.4 12.7 6.2 12.0 12.6 13.8 8.4 11.9 11.5 10.5 8.1 7.3 11.4 8.4 7.3 16.0 10.4 12.2 14.7 21.2 7.4 4.0 13.9 14.4 10.5 34.5 23.0 12.5 3.7 13.1 15.1 10.8 15.5 11.8 7.1 22.1 9.3 10.6 7.0 14.2 5.2 9.8 5.0 12.7 4.9 17.8 19.3 4.6 7.0 7.6 15.1 17.2 6.2 4.8 7.4 15.0 14.9 9.4 14.9 11.0 8.5 8.9 15.6 29.1 24.5 11.6 11.1 14.0 9.3 14.9 20.1 13.0 8.3 22.8 8.7 17.5 11.5 14.2 19.2 5.9 15.1 22.9 8.6 21.3 14.3 7.7 22.5 48.8 10.7 14.7 30.3 15.7 8.6 8.6 39.0 24.1 9.3 14.3 19.5 16.2 25.0 30.8 10.1 13.7 35.5 11.9 12.3 21.3 4.0 10.4 12.4 10.1 12.9 10.8 18.5 36.0 17.8 13.5 11.0 15.5 5.4 4.1 2.7 6.2 2.7 5.7 3.7 7.8 6.0 8.2 4.3 8.7 8.0 1.8 5.0 4.5 7.0 8.3 12.1 11.4 12.7 12.6 13.8 10.4 12.2 13.9 14.4 13.1 14.2 12.7 15.1 11.7 25.6 21.8 14.4 11.7 36.7 36.3 39.7 25.0 52.5 27.5 18.3 56.8 30.0 24.9 22.0 50.1 42.7 8.3 31.5 27.4 15.0 26.7 15.1 9.5 17.1 107.7 48.4 24.1 25.9 53.4 29.3 32.6 14.0 14.0 147.4 23.9 103.1 19.4 26.9 28.6 52.8 34.6 22.4 17.1 8.7 33.2 64.6 30.2 18.7 6.1 47.7 13.4 16.6 20.1 13.9 38.9 34.6 20.6 67.8 78.9 19.2 16.4 42.3 19.7 38.2 21.1 62.7 47.5 39.0 42.6 34.5 14.3 28.6 58.9 44.9 PLA2G12B PLA2G13 ENSG00000138308 "Phospholipase A2 group XIIB" Q9BX93 10 72934762-72954806 "Metabolic proteins, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 33.1;kidney: 14.4;liver: 71.0" "Group enriched" "Detected in some" 4 "Hepatocytes: 52.2;Proximal enterocytes: 70.0" "Cancer enriched" "Detected in many" 8 "liver cancer: 35.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 9.1;Hep G2: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057745, HPA059562" Approved "Secreted to blood" NA NA 2300000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "HPA057745: AB_2683514, HPA059562: AB_2684064" "unprognostic (1.11e-2)" "unprognostic (2.66e-2)" "unprognostic (2.02e-3)" "unprognostic (3.41e-1)" "unprognostic (1.68e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-1)" "unprognostic (3.14e-2)" 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.2 27.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 14.4 71.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.0 0.0 33.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.3 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3.1 1.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.8 52.2 0.0 0.0 0.3 2.4 0.0 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.0 70.0 13.4 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 6.3 0.0 PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322115-120327779 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1519 "pancreas: 117705.6" "Cell type enriched" "Detected in many" 17 "Exocrine glandular cells: 20351.4" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;U-2 OS: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" NA NA 3900000 "Cluster 48: NK-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "HPA047822: AB_2680169, HPA060803: AB_2684369" "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" 10.0 6.5 0.2 1.7 0.1 2.9 5.8 0.2 0.6 5.8 0.0 2.3 15.8 2.3 0.0 3.3 1.8 0.9 21.5 0.2 0.2 2.7 7.2 32.1 4.0 0.1 0.1 77.5 117705.6 0.0 4.4 6.0 0.2 4.4 0.3 0.7 21.3 0.0 1.9 3.4 7.7 0.1 0.1 3.0 8.7 4.3 0.1 0.3 1.5 0.0 0.0 1.3 1.9 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 1.9 0.2 0.2 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.6 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 12.8 91.5 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.8 1.3 0.4 0.0 0.8 0.0 0.0 0.0 0.2 0.2 1.9 24.3 10.6 0.4 0.1 1.1 1.2 0.0 0.1 20351.4 0.0 0.3 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.1 1.2 0.0 0.0 0.0 41.0 3.1 1.5 0.0 1.0 43.9 0.0 2.1 0.0 0.0 1142.1 1.7 3.4 0.1 0.2 4.1 7.6 1.0 0.0 0.0 0.0 3.4 0.5 0.2 0.0 0.1 0.0 0.3 12.5 1.2 0.1 PLA2G2A "PLA2B, PLA2L" ENSG00000188257 "Phospholipase A2 group IIA" P14555 1 19975431-19980416 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" "Antimicrobial, Bacteriolytic enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 1302.4;intestine: 1973.9;placenta: 756.7;urinary bladder: 813.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 536.5;Exocrine glandular cells: 1031.5;Fibroblasts: 656.0;Intestinal goblet cells: 393.6;Paneth cells: 574.1;Prostatic glandular cells: 921.1;Undifferentiated cells: 861.9" "Cancer enhanced" "Detected in all" "prostate cancer: 875.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Hep G2: 645.0;OE19: 2384.4" "Not detected" "Not detected" HPA015236 Enhanced "Secreted to blood" NA NA 1000000 680000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "HPA015236: AB_10601047" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (2.79e-2)" "unprognostic (7.85e-3)" "unprognostic (8.71e-2)" "unprognostic (9.27e-2)" "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.49e-4)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-15)" "unprognostic (2.72e-2)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" 1302.4 7.0 0.1 280.2 0.1 0.0 27.4 0.1 0.7 5.4 2.9 1474.0 786.8 4.3 3.3 29.3 14.8 57.7 137.4 0.0 0.2 6.6 238.6 16.8 5.4 0.6 0.7 44.1 7.8 0.9 2.5 756.7 0.2 203.9 1668.0 0.1 24.6 6.1 6.0 18.1 1973.9 164.4 0.1 0.4 11.6 36.8 1.3 1.7 11.1 114.2 15.0 813.6 12.1 0.1 0.0 0.0 1.6 0.0 248.3 0.0 8.5 0.0 0.1 0.1 0.0 11.2 0.0 0.0 1.1 0.0 0.8 18.7 0.0 0.0 0.0 0.1 0.3 0.0 0.3 645.0 0.0 0.1 1.1 2.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.2 0.4 2384.4 0.0 0.0 0.0 7.6 0.0 198.2 1.0 4.7 0.0 20.1 0.0 31.1 0.1 0.0 0.0 0.0 0.0 44.7 0.2 0.4 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.7 0.0 0.2 0.6 0.7 0.2 0.1 1.3 0.1 20.6 6.4 6.7 0.0 9.1 13.9 10.8 0.2 0.6 0.9 1.0 0.8 14.9 12.8 9.3 0.0 0.0 3.6 0.4 536.5 1.9 0.7 4.0 0.7 43.1 6.9 62.3 13.5 0.0 1031.5 4.6 656.0 6.1 0.6 4.5 0.0 30.0 310.9 9.5 0.0 0.0 393.6 2.0 18.8 31.1 11.6 171.2 3.5 14.2 0.0 0.0 0.0 0.0 0.0 0.0 4.7 574.1 1.2 2.6 921.1 328.2 0.2 1.9 0.0 0.0 2.4 37.8 0.9 1.5 4.9 16.8 6.8 6.2 0.1 861.9 32.2 PLA2G2C UBXN10-AS1 ENSG00000187980 "Phospholipase A2 group IIC" Q5R387 1 20161253-20186518 "Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 1.2" "Group enriched" "Detected in some" 4 "Early spermatids: 2.9;Late spermatids: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 1.6;U-698: 2.0;U-937: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.02e-3)" "unprognostic (2.75e-2)" "unprognostic (5.76e-2)" "unprognostic (3.00e-4)" "unprognostic (9.44e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (3.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.46e-1)" "unprognostic (1.22e-2)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (8.16e-2)" 0.1 0.0 0.4 0.1 0.2 0.4 0.0 0.7 0.5 0.1 0.3 1.2 0.2 0.4 0.2 0.7 0.1 0.1 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.2 0.0 0.1 0.0 0.1 0.2 0.4 0.3 0.2 0.1 0.2 0.2 0.3 0.2 0.2 0.2 0.1 0.2 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.9 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.0 0.1 1.7 0.0 0.5 0.3 0.0 0.4 0.1 0.8 0.1 0.3 0.4 0.5 0.1 0.2 0.1 0.6 0.3 0.0 0.2 0.0 0.1 0.4 0.2 0.7 0.5 0.5 0.3 0.3 0.3 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 1.3 0.1 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.6 0.0 9.8 0.3 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PLA2G2D sPLA2S ENSG00000117215 "Phospholipase A2 group IID" Q9UNK4 1 20111939-20119566 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 106.4" "Cell type enhanced" "Detected in some" "B-cells: 1.6;dendritic cells: 1.3;Kupffer cells: 2.4;Melanocytes: 5.4;Plasma cells: 8.1" "Cancer enriched" "Detected in many" 6 "testis cancer: 25.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory B-cell: 3.7;naive B-cell: 3.6;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 6 "B-cells: 3.7;dendritic cells: 2.0" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.35e-4)" "prognostic favorable (8.15e-5)" "unprognostic (3.88e-3)" "prognostic favorable (9.74e-4)" "unprognostic (1.78e-1)" "unprognostic (2.56e-3)" "unprognostic (1.98e-1)" "unprognostic (1.60e-2)" "unprognostic (1.82e-5)" "unprognostic (7.51e-4)" "unprognostic (2.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (2.60e-1)" 0.7 0.1 0.1 15.8 0.1 0.8 0.9 0.3 0.2 0.3 0.0 2.3 1.4 0.4 0.1 0.4 0.4 1.7 0.2 0.1 0.0 0.1 0.7 2.4 106.4 0.1 0.0 1.0 0.3 0.0 0.0 0.1 0.1 0.4 3.3 0.1 1.2 0.4 0.0 0.2 4.5 0.2 0.0 11.0 2.3 0.4 0.1 3.1 0.3 0.0 59.1 4.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.2 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.4 0.4 0.0 0.0 0.6 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 PLA2G2E ENSG00000188784 "Phospholipase A2 group IIE" Q9NZK7 1 19920009-19923617 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064085 Uncertain "Secreted - unknown location" NA NA "Cluster 16: Immune cells - Immune response" "HPA064085: AB_2685188" "unprognostic (9.56e-2)" "unprognostic (3.71e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.9;esophagus: 13.8;skin 1: 15.4;vagina: 7.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 7.5;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 15.1;AN3-CA: 15.3;NTERA-2: 7.8;SCLC-21H: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021016 Uncertain Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Endoplasmic reticulum" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.8 0.2 5.9 0.7 0.1 0.3 0.0 0.0 13.8 0.0 0.0 0.0 0.4 0.1 0.5 0.0 2.5 0.0 1.6 0.1 0.0 0.0 1.0 0.1 0.0 1.7 0.3 0.0 0.0 1.8 0.3 0.2 15.4 0.2 0.0 0.1 0.0 0.6 0.5 0.1 0.1 0.6 0.0 1.7 0.0 7.1 0.2 0.0 0.0 15.1 15.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.4 0.1 1.6 0.1 1.7 0.1 0.1 0.2 0.0 0.0 3.6 1.6 0.0 1.3 0.2 0.2 0.0 0.0 7.5 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 17.8 0.0 0.0 0.0 0.0 0.4 PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091911 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism, Phagocytosis, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 132.7;ovary: 47.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 75.3;Cone photoreceptor cells: 70.9;Leydig cells: 81.4;Peritubular cells: 73.4;Sertoli cells: 263.0;Smooth muscle cells: 63.1" "Group enriched" "Detected in many" 5 "glioma: 13.0;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2197: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053361 Approved "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA053361: AB_2682127" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-3)" "unprognostic (6.16e-2)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-3)" "unprognostic (6.00e-5)" "unprognostic (2.87e-2)" "unprognostic (3.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.97e-3)" 8.9 1.5 8.7 1.4 10.9 0.0 3.4 10.5 14.4 1.2 22.1 33.7 0.7 1.8 0.9 4.4 6.4 2.0 132.7 9.1 9.7 0.1 6.1 8.0 0.6 10.2 10.9 47.6 0.9 0.0 0.8 4.7 9.2 14.9 2.3 18.9 2.7 7.7 0.5 1.7 3.0 3.3 9.5 1.6 6.3 10.1 11.8 0.0 2.4 0.3 1.2 17.6 1.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 10.9 10.5 14.4 9.1 9.7 10.2 10.9 9.2 9.5 11.8 8.6 0.7 0.0 0.5 25.8 0.0 0.4 0.0 0.0 0.0 11.6 0.2 1.3 75.3 0.0 0.0 0.0 70.9 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.1 0.0 0.0 0.2 0.0 0.1 30.8 0.0 0.0 0.0 6.7 10.8 0.1 0.3 0.0 0.2 0.0 0.0 1.2 0.7 4.9 81.4 0.5 0.0 1.9 0.0 30.8 0.0 0.5 0.1 0.0 0.0 73.4 0.0 1.3 0.0 0.0 0.0 32.1 263.0 0.5 63.1 0.6 0.7 0.0 0.4 0.3 0.1 0.0 0.0 0.1 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.2;placenta: 23.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.2;Macrophages: 140.9" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 49 "dendritic cells: 14.1;monocytes: 43.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;PC-3: 3.4;RT4: 1.6;U-2 OS: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 290000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 4.5 3.1 1.6 22.9 3.6 2.8 2.6 2.7 4.5 2.5 0.4 7.5 4.1 4.8 1.1 0.6 1.9 6.0 0.6 2.6 1.4 0.3 6.9 7.2 26.8 3.9 2.6 1.1 0.8 21.0 2.1 23.3 4.2 13.1 10.3 0.6 1.4 2.6 0.4 3.6 3.3 2.8 2.6 27.2 2.9 0.9 8.9 4.9 20.2 0.0 10.0 11.1 0.3 7.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.7 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 3.4 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.3 43.4 0.3 0.1 9.2 0.3 0.3 0.0 0.0 14.1 0.0 0.0 0.1 0.5 0.0 0.5 0.3 0.0 11.9 1.6 3.6 2.7 4.5 2.6 1.4 3.9 2.6 4.2 2.6 8.9 7.4 0.5 0.0 1.3 0.3 3.6 0.8 4.4 0.0 0.0 0.2 0.3 4.3 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.6 0.1 1.6 50.3 0.6 3.5 0.0 7.1 0.0 5.1 1.8 0.0 1.5 0.0 0.0 0.0 0.0 372.2 1.7 4.8 0.3 0.0 24.6 4.9 0.1 0.0 140.9 10.6 11.2 29.3 0.3 0.0 6.0 0.3 0.3 0.0 0.0 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.9 0.6 0.1 0.0 0.1 0.1 3.1 0.8 8.9 0.2 3.8 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLAC1 "CT92, OOSP2B, OOSP2L" ENSG00000170965 "Placenta enriched 1" Q9HBJ0 X 134565838-134764322 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "placenta: 27.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 24.5;Leydig cells: 5.6;Peritubular cells: 7.9;Spermatocytes: 6.5;Spermatogonia: 11.0;Syncytiotrophoblasts: 10.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 20.1;hTCEpi: 15.6;hTERT-HME1: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000163, HPA063425" Enhanced Approved Vesicles,Cytosol "Secreted in female reproductive system" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles Cytosol "HPA000163: , HPA063425: AB_2685012" "unprognostic (2.93e-1)" "unprognostic (2.50e-3)" "unprognostic (2.89e-4)" "unprognostic (1.35e-7)" "unprognostic (3.83e-3)" "unprognostic (2.07e-2)" "unprognostic (1.63e-2)" "unprognostic (1.26e-1)" "unprognostic (2.01e-1)" "unprognostic (4.28e-2)" "unprognostic (1.48e-2)" "unprognostic (2.87e-2)" "unprognostic (3.33e-16)" "unprognostic (7.64e-3)" "unprognostic (4.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.9 0.0 1.2 0.0 0.2 1.2 0.3 0.4 1.1 0.0 2.0 0.3 0.1 1.8 0.3 0.5 20.1 0.0 0.1 0.3 2.3 0.0 0.0 0.9 15.6 0.1 6.3 0.1 2.4 0.2 0.1 1.7 0.1 1.0 0.0 0.3 0.0 1.3 2.6 0.0 0.3 3.7 0.0 0.0 3.0 0.0 0.0 3.7 0.7 2.2 0.1 0.0 0.0 0.5 0.8 0.2 0.0 0.4 0.1 0.3 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 1.3 0.0 2.8 24.5 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.9 0.0 0.0 0.0 0.0 0.7 5.6 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.5 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 11.0 0.0 0.0 10.7 0.0 2.1 0.0 0.0 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917496 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 103.8;urinary bladder: 128.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 635.9;Basal respiratory cells: 237.3;Pancreatic endocrine cells: 613.9;Prostatic glandular cells: 695.0;Urothelial cells: 869.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 1.1;neutrophil: 2.1;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 11 "dendritic cells: 2.0;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 856.0;LHCN-M2: 822.4;RPTEC TERT1: 3100.7;U-251 MG: 869.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070796 Supported Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 647000 88000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Vesicles" "HPA070796: " "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favorable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" 57.6 4.8 2.5 41.7 2.7 36.2 17.6 2.7 8.9 9.3 4.4 13.1 11.9 22.0 16.7 14.4 10.3 28.5 23.1 2.4 2.9 103.8 5.0 22.0 14.3 3.8 2.9 2.3 10.1 8.3 2.9 36.5 5.4 9.1 18.2 0.3 17.3 13.7 10.8 25.5 13.7 23.4 3.3 40.6 15.7 3.7 4.7 5.9 17.9 18.9 7.2 128.5 16.2 4.7 171.1 88.9 36.8 1.7 3.1 59.5 2.0 101.9 461.6 40.0 62.2 2.3 856.0 0.1 184.0 14.5 416.9 114.1 0.9 165.8 44.8 9.9 0.0 0.1 4.4 1.7 72.6 15.6 32.3 158.7 20.2 271.4 103.7 447.0 114.7 1.0 1.1 0.9 822.4 0.2 0.2 22.7 10.8 0.3 244.5 0.4 112.6 0.9 3100.7 130.6 0.1 0.2 0.3 4.0 2.4 25.4 1.2 22.9 300.6 3.5 20.3 21.6 869.8 0.2 1.3 1.6 216.0 25.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.1 0.0 0.0 2.0 0.0 0.1 2.5 2.7 2.7 8.9 2.4 2.9 3.8 2.9 5.4 3.3 4.7 4.7 29.0 3.2 4.6 0.3 1.4 37.3 635.9 237.3 19.9 0.0 3.0 24.4 2.5 0.0 103.6 29.5 0.0 28.0 1.6 0.6 68.4 62.7 0.5 50.7 22.2 46.4 3.5 0.0 0.2 21.3 21.7 69.7 0.0 68.9 31.1 0.1 3.9 0.0 39.8 0.0 0.3 0.1 140.4 4.0 33.1 1.3 2.5 53.4 7.2 4.7 23.8 0.0 0.0 0.5 0.2 613.9 0.3 0.0 0.5 695.0 0.0 1.4 35.4 0.0 6.6 27.6 65.2 0.0 0.2 60.6 29.5 17.5 4.7 0.6 1.7 869.6 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2666.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1772.7" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" NA NA 140000000000 45000000000 "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.4 0.4 0.3 0.2 0.4 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.3 0.2 0.0 0.1 2.4 0.5 0.1 0.2 0.3 240.9 2666.4 0.4 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 30.0 0.0 1.8 0.0 0.0 0.3 0.0 19.6 0.0 0.2 3.0 0.1 1.2 0.0 24.0 0.6 0.0 0.0 0.0 0.0 0.1 1.3 0.0 28.5 1772.7 0.1 0.0 0.5 0.0 0.0 35.4 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 235.7 1.5 0.1 0.0 0.4 0.2 0.4 0.4 0.0 0.0 0.0 2.3 0.1 0.0 0.0 PLGLB1 "PLGL, PRP-B" ENSG00000183281 "Plasminogen like B1" Q02325 2 87002559-87021852 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in all" 6 "liver: 234.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 95.9" "Cancer enriched" "Detected in single" 7 "liver cancer: 0.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.25e-2)" "unprognostic (7.25e-2)" "unprognostic (2.35e-1)" "unprognostic (1.15e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-5)" "unprognostic (7.04e-3)" "unprognostic (1.15e-1)" "unprognostic (8.53e-4)" "unprognostic (1.60e-1)" "unprognostic (4.56e-4)" "unprognostic (9.90e-3)" "unprognostic (2.96e-5)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (4.32e-2)" "unprognostic (3.98e-5)" 3.6 5.5 19.9 4.5 19.9 8.5 3.6 33.4 26.5 6.9 21.3 4.9 3.9 5.9 8.2 4.0 4.3 4.7 5.9 20.0 20.3 8.5 234.9 3.3 7.9 16.7 17.4 6.7 4.1 2.2 9.5 2.3 16.0 6.6 2.7 42.5 4.8 3.2 8.8 14.2 5.3 2.4 15.0 9.5 4.0 4.3 20.0 7.2 5.6 4.4 4.3 4.9 4.9 19.6 2.7 3.7 4.6 2.6 3.6 5.2 4.5 3.2 2.3 1.7 2.6 2.9 6.9 7.3 3.3 1.3 1.3 2.4 1.2 0.5 1.8 8.2 3.1 5.8 6.6 3.1 2.5 3.5 1.5 4.0 4.2 4.7 4.8 7.9 0.8 8.0 3.0 5.9 2.2 3.9 13.3 11.5 5.9 2.4 2.4 3.1 1.7 3.9 4.5 2.9 3.6 4.0 2.9 2.5 2.7 4.6 1.3 7.6 5.0 3.3 2.3 2.3 2.0 6.7 5.1 2.9 1.9 4.7 1.9 1.9 0.3 0.4 0.7 0.1 0.6 1.2 0.7 0.5 0.1 0.8 0.9 0.5 1.0 0.4 0.3 0.6 1.1 0.1 19.9 19.9 33.4 26.5 20.0 20.3 16.7 17.4 16.0 15.0 20.0 19.6 1.3 0.0 3.4 0.7 1.0 1.1 0.3 0.4 1.2 10.3 1.1 1.0 2.6 1.5 1.5 0.0 6.2 0.2 1.5 0.7 0.0 1.1 0.8 1.0 1.0 1.6 1.2 4.0 0.9 0.2 0.2 1.6 0.5 0.9 0.0 1.0 1.8 95.9 0.2 5.0 1.1 2.5 0.0 1.3 0.4 0.3 1.2 1.1 3.6 0.0 1.6 2.7 1.0 0.0 0.8 0.3 0.3 1.9 0.9 0.5 0.7 1.8 2.3 18.2 0.0 2.5 1.0 0.7 0.5 1.5 1.3 0.0 1.4 0.9 0.9 0.3 PLGLB2 PLGP1 ENSG00000125551 "Plasminogen like B2" Q02325 2 87748087-87759476 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in some" 163 "liver: 454.4" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 76.3" "Cancer enriched" "Detected in single" 25 "liver cancer: 1.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 12: NES - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.10e-2)" "unprognostic (8.78e-2)" "unprognostic (3.42e-2)" "unprognostic (7.03e-4)" "unprognostic (1.68e-2)" "unprognostic (3.77e-1)" "unprognostic (1.82e-2)" "unprognostic (5.74e-2)" "unprognostic (2.94e-1)" "unprognostic (5.04e-4)" "unprognostic (6.39e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-2)" "unprognostic (7.11e-2)" 0.4 0.8 1.0 0.5 0.7 0.5 0.3 2.0 1.0 0.8 0.2 0.3 0.2 0.6 0.6 0.6 0.7 0.2 0.8 0.9 0.1 0.9 454.4 0.3 0.9 0.2 0.3 0.5 1.3 0.4 0.9 0.4 0.2 0.7 0.3 2.7 0.4 0.4 0.6 1.0 0.5 0.2 0.1 0.9 0.5 1.0 0.2 0.8 0.5 0.5 0.7 0.3 0.2 0.6 0.0 0.1 1.2 0.3 0.4 0.5 0.4 0.6 0.4 0.1 0.2 0.1 0.3 0.7 0.4 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.5 1.2 0.0 0.1 0.5 0.2 0.5 0.3 0.1 0.2 1.0 0.4 0.7 0.0 0.1 0.4 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.4 0.0 0.0 0.7 0.2 0.2 0.0 0.3 0.0 0.3 0.2 0.1 0.5 0.4 0.3 0.5 1.2 0.3 0.4 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.0 0.1 0.0 1.0 0.7 2.0 1.0 0.9 0.1 0.2 0.3 0.2 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 4.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 76.3 0.1 0.0 0.3 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 115.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 20.3;monocytes: 22.5;T-cells: 12.6" "Cell line enhanced" "Detected in all" "Karpas-707: 695.6;WM-115: 680.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001236 Uncertain "Secreted to extracellular matrix" NA NA 1600000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA001236: AB_1855474" "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" 41.9 27.3 43.6 22.9 53.2 19.6 32.8 54.9 58.5 33.3 46.8 37.8 25.7 38.9 11.7 12.2 32.5 18.8 42.6 43.6 46.3 36.3 54.1 37.5 14.6 61.1 52.3 26.3 41.8 21.5 27.1 35.0 58.9 24.2 15.3 3.9 19.4 18.6 15.3 19.1 35.9 26.0 49.4 35.3 30.0 12.9 51.7 8.0 25.3 11.8 7.5 35.2 25.2 71.9 71.7 62.4 27.1 168.2 116.2 83.9 51.4 125.5 135.9 122.7 88.6 98.0 89.0 5.6 140.2 211.4 100.7 83.0 50.0 72.0 31.2 37.8 23.8 7.2 70.7 97.3 157.6 31.5 57.4 90.8 67.6 71.6 55.4 120.2 110.9 4.6 68.4 695.6 84.2 194.5 3.4 72.1 53.5 120.5 94.9 21.8 35.1 108.3 42.0 19.1 21.2 116.0 81.1 116.2 288.1 66.8 21.9 105.2 100.5 188.1 94.9 228.1 155.0 38.5 75.9 5.2 112.4 74.2 680.2 0.0 18.1 4.4 12.6 21.8 10.9 3.7 9.3 8.3 16.5 2.2 4.1 4.5 1.8 3.6 22.5 20.3 6.7 9.5 43.6 53.2 54.9 58.5 43.6 46.3 61.1 52.3 58.9 49.4 51.7 71.9 34.1 22.4 8.7 11.1 9.7 8.9 10.8 18.9 8.0 5.7 8.1 9.1 16.1 21.5 8.7 25.8 14.6 20.4 22.0 37.6 1.9 40.2 0.6 10.8 29.9 28.5 16.2 19.1 11.9 31.6 71.6 34.2 17.9 20.5 19.7 25.9 26.7 18.3 50.1 8.4 10.8 18.0 4.1 23.3 18.3 2.1 26.1 23.2 62.2 4.7 18.9 7.7 12.3 10.1 33.4 36.1 37.8 14.7 19.7 8.0 45.8 8.8 9.3 7.3 19.7 14.3 29.8 8.9 12.4 1.9 4.8 18.9 12.5 18.4 27.3 5.2 PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 1640.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 220.8;BEWO: 186.8;HHSteC: 233.2;HSkMC: 302.2;U-87 MG: 326.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" 437.9 188.9 107.9 80.5 109.8 20.7 122.6 100.8 142.0 155.4 197.6 76.9 41.6 114.9 72.6 62.0 173.5 182.3 123.4 100.4 119.0 198.9 29.5 97.1 61.3 119.5 152.2 159.5 296.9 22.1 38.5 428.8 126.0 50.7 42.4 4.8 132.1 71.5 24.0 68.0 71.6 181.9 124.7 57.6 89.7 32.3 114.5 229.9 44.4 20.8 21.1 339.7 113.1 118.1 13.8 1.9 94.9 0.1 220.8 66.8 186.8 5.3 16.3 18.5 11.0 78.7 15.9 3.5 151.6 23.6 0.4 154.7 29.2 0.6 8.4 1.8 0.2 28.8 3.3 37.7 233.2 0.0 35.5 302.2 7.7 49.1 0.9 74.1 41.3 3.2 9.5 44.9 6.2 3.9 3.2 123.1 16.9 12.5 74.5 1.3 0.1 1.7 0.5 0.0 10.1 35.4 3.7 110.3 160.9 15.7 1.5 117.2 9.0 46.2 1.1 24.2 0.8 19.7 5.3 5.4 326.4 34.3 7.8 33.1 2.7 29.7 1.6 7.1 1.2 8.7 0.4 1.6 2.5 3.2 0.0 1.0 1.4 4.9 12.6 17.5 0.8 2.7 107.9 109.8 100.8 142.0 100.4 119.0 119.5 152.2 126.0 124.7 114.5 118.1 21.9 0.0 2.3 30.3 3.8 40.7 34.9 53.0 33.0 0.4 9.5 22.6 1.5 5.7 9.6 27.6 0.0 14.8 3.5 0.5 1.9 3.4 16.3 54.6 36.9 27.9 0.0 9.0 0.8 103.2 97.7 256.8 3.6 5.7 0.0 23.4 121.1 2.8 1640.3 3.3 1.4 1.2 12.2 254.0 40.9 24.9 307.9 71.8 35.6 4.7 3.8 13.8 7.2 0.5 0.2 9.9 0.0 199.0 11.8 15.7 0.0 18.2 70.8 1.1 32.9 16.1 35.6 5.7 7.3 24.0 35.8 31.7 3.3 99.5 0.7 18.4 PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 78.0;skin 1: 33.8" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 20.9;Gastric mucus-secreting cells: 7.1;Proximal tubular cells: 7.1" "Cancer enriched" "Detected in some" 32 "urothelial cancer: 30.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Cell line enriched" "Detected in single" 9 "Karpas-707: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA 3300000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (4.83e-1)" "unprognostic (4.08e-3)" "unprognostic (1.17e-3)" "unprognostic (3.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.81e-2)" "unprognostic (4.57e-2)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" 0.8 0.0 0.2 0.1 0.2 0.0 1.2 0.0 0.3 0.1 1.2 0.1 0.1 0.1 0.5 0.0 0.4 0.0 0.3 0.2 0.3 6.3 0.2 0.2 1.1 0.3 0.3 0.3 78.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 33.8 0.1 0.0 0.2 1.0 2.9 0.0 0.3 0.1 0.1 0.0 0.4 2.2 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 0.0 0.5 0.1 0.4 1.3 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 2.2 0.3 0.2 0.2 0.0 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.3 0.8 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.6 0.5 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.0 0.9 0.1 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.4 3.2 20.9 0.3 0.5 7.1 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.5 0.2 0.0 1.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.0 1.5 1.5 0.6 0.0 0.0 1.8 0.2 0.0 7.1 0.0 0.8 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.9 2.4 0.0 0.1 PMCH MCH ENSG00000183395 "Pro-melanin concentrating hormone" P20382 12 102196459-102197833 "Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hormone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "brain: 92.8" "Group enriched" "Detected in some" 4 "B-cells: 2.7;Exocrine glandular cells: 2.0;monocytes: 1.0;T-cells: 1.7" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.8" "Region enhanced" "Detected in many" "hypothalamus: 92.8;thalamus: 60.2" "Immune cell enriched" "Detected in some" 10 "T-reg: 9.5" "Lineage enriched" "Detected in single" 85 "T-cells: 9.5" "Cell line enriched" "Detected in some" 8 "HDLM-2: 44.9" "Group enriched" "Detected in many" 129 "hypothalamus: 624.3;thalamus: 339.8" "Region enriched" "Detected in some" 34 "hypothalamus: 83.0" "HPA046055, HPA061884" Enhanced Supported "Secreted to blood" NA NA 274000 "Cluster 35: T-regs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA046055: AB_2679517, HPA061884: AB_2684632" "unprognostic (3.23e-3)" "unprognostic (8.04e-2)" "unprognostic (3.96e-4)" "unprognostic (2.09e-2)" "unprognostic (1.75e-1)" "unprognostic (7.73e-2)" "unprognostic (4.31e-3)" "unprognostic (1.43e-2)" "unprognostic (3.18e-3)" "unprognostic (4.51e-2)" "unprognostic (1.21e-1)" "unprognostic (2.16e-6)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "unprognostic (5.10e-2)" "unprognostic (3.53e-2)" 0.0 0.0 0.2 0.5 2.7 0.6 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 92.8 0.0 0.0 0.1 1.0 0.3 22.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.0 0.0 0.4 0.5 0.0 60.2 1.0 0.0 0.1 0.4 0.1 0.0 0.0 0.4 0.2 0.5 0.4 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.2 0.2 0.0 0.0 0.0 44.9 0.0 0.7 0.8 0.4 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.2 5.3 0.5 0.9 0.0 0.0 0.0 0.8 1.5 0.6 0.7 1.3 0.4 0.6 1.8 0.0 0.3 0.5 0.5 0.6 0.8 0.1 0.3 0.3 0.1 0.6 0.6 0.5 0.2 0.7 0.1 0.8 0.6 0.5 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.2 2.7 0.1 0.3 0.0 92.8 0.3 22.2 0.3 0.0 60.2 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 PNLIP PL ENSG00000175535 "Pancreatic lipase" P16233 10 116545931-116567855 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2058 "pancreas: 444687.5" "Cell type enriched" "Detected in some" 8 "Exocrine glandular cells: 4086.8" "Cancer enriched" "Detected in some" 4854 "pancreatic cancer: 2731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.3" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA062430, HPA062494" Enhanced "Secreted to digestive system" NA NA 14000000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA062430: AB_2684761, HPA062494: AB_2684782" "unprognostic (2.05e-2)" "unprognostic (4.46e-2)" 13.8 3.1 0.0 10.5 0.0 1.1 8.9 0.0 0.0 7.2 0.0 3.8 64.8 9.1 0.4 4.8 1.5 0.0 78.2 0.0 0.0 3.0 10.2 2.1 16.9 0.0 0.0 216.0 444687.5 0.0 2.5 24.4 0.0 4.5 0.0 0.0 71.7 0.0 2.9 4.6 34.0 0.0 0.0 3.8 28.2 2.3 0.0 0.0 2.0 0.0 0.0 1.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.5 0.0 0.0 0.3 0.0 0.0 0.1 4086.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 14.5 0.0 0.0 0.5 0.1 507.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PNLIPRP1 PLRP1 ENSG00000187021 "Pancreatic lipase related protein 1" P54315 10 116590385-116609175 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2343 "pancreas: 10825.1" "Cell type enriched" "Detected in some" 10 "Exocrine glandular cells: 688.3" "Cancer enriched" "Detected in single" 476 "pancreatic cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/84: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 340000 "Cluster 25: Pancreas - Digestion" "Cluster 16: U-266 - Nucleosome" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (1.21e-1)" "unprognostic (4.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.76e-2)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" 1.7 0.2 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.9 0.0 0.2 2.1 0.3 0.0 0.4 0.1 0.0 2.0 0.0 0.0 0.2 0.8 0.2 0.4 0.0 0.0 4.6 10825.1 0.0 0.5 0.8 0.0 0.4 0.1 0.0 2.7 0.0 0.2 0.4 1.1 0.0 0.0 0.4 1.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 688.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 3.4 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.1 66.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.3 PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427847-116477957 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 9.0;skin 1: 14.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.1;Early spermatids: 1.5;Late spermatids: 1.9;Melanocytes: 1.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "hTCEpi: 320.3" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA046202: AB_10959739, HPA052009: AB_2681692" "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" 2.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 320.3 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;fallopian tube: 18.2;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 61.5;dendritic cells: 12.6;Inhibitory neurons: 23.3;Melanocytes: 14.2;Plasma cells: 80.4" "Cancer enriched" "Detected in many" 8 "ovarian cancer: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 231.2;naive B-cell: 260.3;plasmacytoid DC: 194.0" "Group enriched" "Detected in many" 20 "B-cells: 260.3;dendritic cells: 194.0" "Group enriched" "Detected in some" 6 "Daudi: 38.3;Karpas-707: 29.2;RPMI-8226: 11.2;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced "Secreted to blood" NA NA 12300 "Cluster 19: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA044507: AB_10795043, HPA056724: AB_2683216" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.94e-6)" "unprognostic (3.71e-2)" "unprognostic (5.16e-5)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (7.81e-4)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" "unprognostic (7.57e-9)" "unprognostic (2.19e-2)" "unprognostic (5.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-1)" 0.2 0.8 5.4 9.9 5.1 2.7 0.6 1.3 10.8 0.2 1.3 2.9 4.3 0.1 0.0 0.6 18.2 1.1 0.1 2.9 9.9 0.7 0.2 1.0 25.1 10.4 6.3 0.4 0.0 0.0 0.0 0.0 9.9 0.2 1.5 0.0 1.6 0.1 0.0 0.1 5.8 0.5 14.3 14.4 3.2 0.6 4.3 2.7 0.4 0.0 23.6 3.7 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 4.0 4.4 23.0 0.1 0.1 0.0 0.2 11.5 2.3 0.2 7.7 0.1 231.2 0.2 0.1 1.1 260.3 0.1 0.1 1.3 1.2 3.2 194.0 0.5 11.1 5.4 5.1 1.3 10.8 2.9 9.9 10.4 6.3 9.9 14.3 4.3 3.0 0.1 0.0 1.9 1.3 61.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.4 0.4 0.2 0.0 23.3 0.1 0.0 0.0 0.3 2.8 0.3 1.7 14.2 1.0 3.0 0.0 1.0 0.0 0.9 0.1 0.0 0.0 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 1.1 0.0 0.3 0.5 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 PODNL1 "FLJ23447, SLRR5B" ENSG00000132000 "Podocan like 1" Q6PEZ8 19 13931187-13953392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 13.4;Bipolar cells: 38.7;Leydig cells: 18.3;Peritubular cells: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 6.6;HSkMC: 11.6;hTERT-RPE1: 18.8;SiHa: 9.7;U-2 OS: 6.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 11 "spinal cord: 18.9" HPA042807 Approved "Secreted - unknown location" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "HPA042807: AB_10795514" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (8.08e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.61e-8)" "unprognostic (1.78e-1)" "unprognostic (1.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-3)" "unprognostic (4.37e-2)" "unprognostic (1.01e-1)" "unprognostic (0.00e+0)" "unprognostic (3.94e-3)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.49e-4)" 1.8 0.7 1.9 0.9 1.7 0.5 4.9 2.3 1.8 5.6 0.8 2.8 0.4 1.5 0.2 8.2 2.1 1.3 4.7 1.2 3.6 1.7 0.5 5.1 0.2 4.3 4.4 3.3 1.5 0.1 5.1 3.7 3.0 7.9 0.3 2.0 5.3 0.9 1.6 11.4 2.3 0.5 3.1 1.0 1.7 7.2 3.7 0.0 3.1 1.3 0.2 2.7 12.0 2.0 0.3 0.4 0.4 0.2 0.6 1.5 0.1 4.1 2.4 0.8 1.6 0.3 0.4 0.2 0.3 6.6 0.2 1.6 0.1 0.1 0.4 1.5 0.6 0.8 0.4 0.0 5.1 0.2 0.5 11.6 0.7 1.1 0.1 18.8 0.0 0.1 0.4 0.3 1.6 2.7 0.2 0.2 0.1 0.3 0.4 0.1 0.1 0.0 0.3 0.0 0.7 0.4 9.7 0.1 0.3 0.4 0.1 0.5 0.7 2.0 6.7 0.5 0.2 0.3 0.0 0.1 0.8 0.9 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.9 1.7 2.3 1.8 1.2 3.6 4.3 4.4 3.0 3.1 3.7 2.0 1.4 0.0 0.5 2.3 0.0 1.3 0.9 13.4 0.0 38.7 2.1 8.0 1.6 0.0 1.4 0.0 2.1 0.4 0.2 1.8 0.0 0.2 1.7 0.5 6.1 0.9 0.0 2.7 0.5 0.0 0.2 4.7 0.0 0.4 0.0 0.5 0.7 0.1 9.8 1.7 0.7 1.1 0.0 1.2 1.7 2.1 18.3 0.9 1.8 1.9 0.0 1.8 0.0 1.5 0.3 0.6 9.0 38.0 0.0 0.5 0.6 0.1 1.4 4.6 0.0 0.6 1.0 1.0 0.7 2.6 4.3 0.8 0.2 0.1 1.4 1.6 POMC "ACTH, CLIP, LPH, MSH, NPP, POC" ENSG00000115138 Proopiomelanocortin P01189 2 25160853-25168903 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Endorphin, Hormone" "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 903 "pituitary gland: 34360.0" "Cell type enhanced" "Detected in many" "Early spermatids: 119.8;Late spermatids: 352.6;Spermatocytes: 83.0" "Cancer enriched" "Detected in many" 6 "testis cancer: 18.5" "Group enriched" "Detected in all" 6 "hypothalamus: 38.0;thalamus: 13.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;THP-1: 2.1" "Region enriched" "Detected in all" 7 "hypothalamus: 44.0" "Region enriched" "Detected in all" 5 "hypothalamus: 88.1" "CAB002762, HPA046135, HPA063644, CAB079881" Enhanced "Secreted to blood" NA NA 380000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "CAB002762: , CAB079881: , HPA046135: AB_2679552, HPA063644: AB_2685071" "unprognostic (8.02e-2)" "unprognostic (1.47e-2)" "unprognostic (4.78e-2)" "unprognostic (1.96e-3)" "unprognostic (3.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.30e-2)" "unprognostic (8.74e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.70e-4)" "unprognostic (8.02e-2)" "unprognostic (4.29e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (3.84e-2)" 6.1 19.1 2.7 1.2 2.8 1.1 3.5 3.2 4.4 3.0 2.2 6.9 0.4 3.1 0.3 13.7 2.2 0.2 12.1 2.3 38.0 4.9 12.9 3.5 1.1 4.5 3.3 5.0 22.6 0.1 34360.0 1.2 3.7 5.0 0.0 0.2 5.8 0.3 5.7 35.7 4.8 0.1 4.0 11.1 15.5 25.7 13.1 1.2 8.4 5.2 0.4 2.5 3.7 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 12.6 8.6 11.5 13.2 9.1 16.8 8.8 11.3 15.9 17.4 11.6 12.6 3.8 18.2 8.0 27.9 10.5 9.7 2.7 2.8 3.2 4.4 2.3 38.0 4.5 3.3 3.7 4.0 13.1 3.5 22.3 0.0 2.2 1.0 16.1 4.5 2.2 6.9 2.2 2.6 6.1 6.7 2.5 2.8 2.5 0.0 0.0 0.5 24.4 0.2 15.6 7.8 119.8 0.6 4.9 11.6 0.0 28.8 0.3 17.3 6.0 5.2 4.6 0.6 7.0 9.7 15.4 2.0 34.5 6.7 0.6 0.0 6.1 10.9 7.9 352.6 4.7 17.2 17.8 1.9 8.5 11.5 15.5 0.0 0.3 10.1 1.1 13.2 17.8 4.1 0.1 3.9 0.7 7.5 13.1 4.6 3.8 83.0 27.3 1.6 5.5 0.4 14.9 12.9 0.6 3.8 PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324532 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "liver: 531.8" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 440.0" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" NA NA 96000000000 17000000000 "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favorable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" 0.0 4.1 0.6 0.0 0.5 0.0 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.5 0.6 0.2 531.8 0.1 0.0 0.5 0.5 0.6 0.1 0.0 0.8 0.0 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.6 5.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.6 0.5 0.6 0.5 0.5 0.5 0.3 0.6 0.6 0.0 0.0 1.5 7.2 1.1 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.6 18.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.4 3.0 13.5 0.2 0.2 0.0 0.2 0.0 0.3 0.0 0.1 8.9 440.0 0.0 0.0 0.2 0.2 0.0 13.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 1.6 0.5 0.4 0.2 0.0 0.1 0.0 0.6 0.5 0.3 0.1 PON2 ENSG00000105854 "Paraoxonase 2" Q15165 7 95404862-95435329 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 258.9" "Cell type enhanced" "Detected in many" "Astrocytes: 341.5;Extravillous trophoblasts: 300.9;Skeletal myocytes: 284.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 33.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025430, HPA029193" Enhanced "Secreted to blood" NA NA 160000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025430: , HPA029193: AB_10602148" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-5)" "unprognostic (3.80e-1)" "unprognostic (4.14e-1)" "unprognostic (3.89e-2)" "unprognostic (3.77e-3)" "unprognostic (1.19e-3)" "unprognostic (9.87e-3)" "unprognostic (9.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (1.40e-1)" "unprognostic (6.43e-2)" "unprognostic (7.99e-3)" "unprognostic (2.56e-1)" 50.6 129.9 196.0 22.7 206.2 10.9 62.6 184.9 258.9 43.3 150.1 69.0 81.6 45.9 61.2 28.6 41.3 53.3 45.5 192.1 209.8 56.5 183.7 105.4 14.3 183.6 197.1 31.6 26.8 28.4 49.8 98.3 186.0 39.5 86.0 30.2 29.9 45.6 15.4 56.6 51.0 51.5 182.0 22.3 27.6 28.3 197.9 13.9 37.7 17.5 33.0 37.6 30.3 205.7 51.1 313.4 250.6 137.2 34.2 74.5 69.6 101.5 118.7 77.3 83.7 72.1 113.8 0.0 138.4 100.9 148.2 33.3 46.2 78.3 87.4 0.8 59.8 25.9 186.3 238.1 53.9 0.1 34.1 108.6 88.7 41.7 56.5 157.8 162.7 0.0 16.9 1.0 231.1 46.6 0.1 29.2 49.2 135.4 71.4 0.0 117.5 12.5 239.4 39.4 17.2 53.5 144.7 159.8 102.9 142.7 47.3 17.0 178.3 115.7 83.7 39.6 100.2 26.2 32.5 0.4 108.1 23.9 154.3 0.0 7.8 0.8 5.0 4.3 4.5 1.6 1.9 4.5 33.8 0.5 2.5 3.5 0.0 8.9 2.3 8.1 1.1 4.4 196.0 206.2 184.9 258.9 192.1 209.8 183.6 197.1 186.0 182.0 197.9 205.7 65.7 128.2 104.3 341.5 4.6 16.8 42.8 201.4 25.6 5.6 51.0 37.6 39.4 67.2 178.5 84.6 0.0 75.6 13.9 121.4 9.8 149.9 5.5 29.9 32.0 86.5 12.6 26.1 0.7 50.6 300.9 36.3 20.4 57.0 14.5 55.2 44.3 151.7 40.5 38.7 1.8 36.3 173.0 20.8 63.7 2.6 16.1 27.4 112.1 72.1 17.4 185.0 10.3 126.2 149.2 75.7 102.2 21.8 4.9 25.7 85.7 55.8 64.6 8.2 19.7 284.5 49.2 2.6 7.5 25.4 16.1 50.3 8.1 44.5 81.0 23.4 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 616.7" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 509.6" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 28.9;CACO-2: 8.6;CAPAN-2: 6.5;Hep G2: 32.6;T-47d: 17.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA014848, CAB025250" Enhanced "Secreted to blood" NA NA 1760000000 380000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 1.4 3.8 2.1 0.5 2.0 0.0 31.2 1.7 1.9 5.3 1.4 2.0 7.9 0.9 3.6 0.5 1.3 4.4 1.0 1.8 2.1 2.7 616.7 14.2 0.1 2.3 2.2 12.4 14.3 0.2 24.9 0.8 2.9 0.9 2.8 0.1 26.3 3.9 0.3 7.4 3.1 0.2 2.1 0.3 2.3 9.0 2.1 1.6 7.1 0.3 5.9 1.4 0.9 1.9 3.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.1 17.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 1.7 1.9 1.8 2.1 2.3 2.2 2.9 2.1 2.1 1.9 2.5 6.4 45.9 24.5 0.6 0.9 0.9 9.3 1.8 0.0 5.4 4.3 0.5 31.5 23.9 3.7 0.0 1.7 0.3 3.2 1.9 0.3 14.5 0.0 0.4 1.9 0.0 8.0 0.1 2.0 2.2 5.2 0.5 0.0 0.0 0.4 10.0 509.6 0.2 0.0 0.2 1.8 12.2 8.1 0.3 4.8 8.1 0.2 14.2 4.7 0.0 3.2 0.0 17.6 0.1 1.2 1.2 3.0 0.0 2.1 6.0 6.7 6.5 0.1 0.0 0.8 2.1 21.4 16.9 0.3 1.3 1.4 0.8 6.6 2.3 0.4 POSTN "OSF-2, periostin, PN" ENSG00000133110 Periostin Q15063 13 37562583-37598844 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 207.2;stomach 1: 174.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 295.7;Breast myoepithelial cells: 158.1;Endothelial cells: 134.6;Fibroblasts: 191.5;Smooth muscle cells: 151.5" "Cancer enhanced" "Detected in all" "breast cancer: 231.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTEC/SVTERT24-B: 490.2;SuSa: 440.5;U-138 MG: 619.3;U-2197: 427.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 87.9" HPA012306 Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to extracellular matrix" NA NA 660000000 "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Nucleoplasm "HPA012306: AB_1854827" "unprognostic (7.73e-2)" "unprognostic (1.44e-3)" "unprognostic (2.19e-2)" "unprognostic (2.57e-2)" "unprognostic (4.73e-2)" "unprognostic (2.22e-2)" "unprognostic (4.19e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (3.05e-3)" "unprognostic (7.10e-2)" "unprognostic (1.32e-2)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.83e-7)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (8.32e-3)" 71.4 5.2 4.5 23.8 0.1 0.3 84.0 0.0 4.4 20.3 2.9 61.3 5.1 53.2 13.0 20.5 83.5 64.3 83.2 3.0 0.0 28.1 13.0 45.1 12.8 0.9 0.0 3.6 2.2 21.6 2.4 60.9 2.0 16.1 84.9 0.0 17.7 44.8 10.6 207.2 15.0 66.6 0.0 1.1 174.6 3.4 0.1 5.8 19.1 29.9 3.9 91.4 10.7 0.4 0.0 0.0 71.0 1.6 85.0 51.0 0.2 23.1 0.0 5.5 0.7 0.0 1.4 0.1 0.0 18.7 0.1 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.0 14.2 0.2 0.1 90.8 0.0 490.2 1.9 15.9 0.7 0.0 0.0 0.0 11.8 0.0 0.3 0.4 4.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.4 0.2 0.1 0.6 0.0 440.5 0.9 0.0 0.0 619.3 0.3 427.2 3.4 0.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.0 4.4 3.0 0.0 0.9 0.0 2.0 0.0 0.1 0.4 46.7 6.4 10.6 0.7 0.3 295.7 1.3 51.5 0.0 0.0 2.9 158.1 22.8 0.0 18.7 0.0 0.0 2.5 1.0 0.0 0.0 0.0 0.5 0.5 9.8 134.6 0.0 0.0 1.5 0.0 0.2 191.5 0.0 0.3 3.8 0.0 22.5 0.6 3.7 0.0 36.8 0.0 24.4 0.0 27.0 1.1 6.5 0.8 30.2 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.7 0.4 0.4 0.0 0.0 5.6 0.0 0.0 0.7 151.5 1.3 0.9 0.2 48.4 3.4 2.3 49.3 0.0 0.3 PPBP "b-TG1, Beta-TG, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2-L1, PBP, SCYB7, TGB, TGB1, THBGB1" ENSG00000163736 "Pro-platelet basic protein" P02775 4 73986439-73988190 "Plasma proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 98.7;lymphoid tissue: 53.6" "Cell type enriched" "Detected in some" 18 "Macrophages: 1497.3" "Cancer enriched" "Detected in many" 7 "colorectal cancer: 86.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 13 "basophil: 394.2;neutrophil: 132.3" "Lineage enriched" "Detected in all" 20 "granulocytes: 394.2" "Cell line enhanced" "Detected in some" "HBEC3-KT: 1.0;HEL: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008354, CAB017624" Supported "Secreted to blood" NA NA 24500000 2900000000 "Cluster 34: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "CAB017624: AB_1127132, HPA008354: AB_1847353" "unprognostic (2.13e-1)" "prognostic unfavorable (6.17e-4)" "unprognostic (7.69e-2)" "unprognostic (1.67e-1)" "unprognostic (4.37e-2)" "unprognostic (3.13e-1)" "unprognostic (2.79e-1)" "unprognostic (6.98e-3)" "unprognostic (2.58e-1)" "unprognostic (4.21e-2)" "unprognostic (1.81e-1)" "unprognostic (2.88e-1)" "unprognostic (2.38e-3)" "unprognostic (1.49e-1)" "unprognostic (2.90e-1)" "unprognostic (2.15e-3)" "unprognostic (2.59e-2)" 1.3 0.5 0.3 0.5 0.4 98.7 0.6 0.3 2.2 0.1 1.0 0.1 0.0 0.1 0.0 0.2 0.8 0.8 1.3 0.2 0.3 0.9 2.9 19.4 0.0 0.5 0.4 0.1 0.1 0.0 0.4 5.2 0.8 0.1 0.0 0.0 0.6 0.0 1.4 0.1 0.0 0.1 0.8 53.6 0.2 0.0 0.7 0.1 1.0 4.2 0.0 8.4 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 394.2 13.0 9.3 2.0 5.3 2.9 1.5 1.2 0.6 8.0 2.3 4.1 1.0 132.3 1.9 5.0 20.1 2.1 1791.5 0.3 0.4 0.3 2.2 0.2 0.3 0.5 0.4 0.8 0.8 0.7 0.4 0.3 3.2 1.1 0.0 10.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 4.0 1.8 0.0 0.0 9.3 0.1 0.0 4.7 0.0 0.0 0.0 12.3 0.0 2.7 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 36.8 1.1 0.1 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 1497.3 0.0 0.0 80.8 0.0 75.2 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.0 0.3 1.7 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.1 7.8 0.0 0.0 0.0 PPIA CYPA ENSG00000196262 "Peptidylprolyl isomerase A" P62937 7 44796680-44824564 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004655, HPA058345" Uncertain "Secreted to blood" NA NA 230000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "CAB004655: AB_425607, HPA058345: AB_2683685" "unprognostic (3.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.86e-2)" "unprognostic (9.27e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.12e-3)" "unprognostic (3.30e-2)" "unprognostic (3.92e-2)" "unprognostic (8.68e-3)" "unprognostic (2.52e-1)" "unprognostic (6.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (7.84e-2)" "unprognostic (1.16e-1)" 1148.4 1085.6 1707.2 714.4 1757.6 1052.9 1368.0 1733.9 2245.6 943.7 1718.8 1352.6 603.7 854.8 981.6 2149.0 771.3 548.8 781.6 1785.4 1791.4 1412.8 1318.6 1099.2 1067.1 1857.4 1728.1 799.5 967.7 1286.3 670.1 805.9 1860.7 766.1 1196.0 496.7 1020.3 782.9 566.1 1516.0 953.4 943.4 1767.2 1134.4 896.7 366.0 1742.4 2333.2 884.9 517.9 1647.3 1339.3 1208.7 1822.8 2141.8 3020.1 3731.1 2509.6 2798.6 4154.8 1115.0 3173.6 4588.0 5531.3 5393.2 3414.3 3127.1 4614.1 1893.1 3828.8 6554.2 3209.5 4495.7 5727.5 5062.6 2674.3 3204.3 1883.6 3911.6 4682.5 2255.3 3890.0 2246.2 3103.5 3820.5 3988.9 4295.5 2888.1 5717.2 3277.9 3933.2 3789.6 5790.6 3665.7 4667.5 7562.4 4612.9 7628.9 3689.2 3554.4 2050.1 5969.7 8018.9 4215.4 2548.3 2218.7 2500.5 7185.8 2493.3 4091.8 4303.8 5202.3 2587.0 2865.0 3656.5 2027.1 4050.5 3861.7 6522.3 9409.0 2614.0 4314.6 4455.2 475.6 1239.3 594.8 1421.6 1449.2 1534.2 2104.8 1500.3 1491.1 2196.1 1769.5 1217.2 1394.4 133.3 1349.0 1374.8 2618.5 2085.4 3631.4 1707.2 1757.6 1733.9 2245.6 1785.4 1791.4 1857.4 1728.1 1860.7 1767.2 1742.4 1822.8 713.8 794.9 759.9 37.2 1037.1 866.6 867.8 1097.5 1878.1 94.3 1226.2 1628.0 47.6 526.1 743.6 603.2 18.8 852.7 1067.7 658.4 1414.6 1172.4 78.2 539.3 770.8 719.7 529.6 1120.3 57.3 1218.7 1683.7 672.4 820.1 862.1 622.1 650.0 669.7 766.9 1582.1 111.0 50.4 1003.5 587.9 1110.0 786.1 81.4 582.2 988.1 691.9 41.2 1283.2 221.6 995.9 27.2 79.8 1222.6 715.0 613.1 1215.3 922.1 831.6 1636.8 481.4 101.5 394.4 588.7 942.7 366.7 246.1 2608.3 990.4 609.2 924.5 1157.5 1262.6 947.0 PPIB "B, CYP-S1, CYPB, OI9, PPIase, SCYLP" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155740-64163134 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Isomerase, Rotamase" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1473.7;Plasma cells: 2242.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" No No 33000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" 375.5 377.5 230.7 449.5 240.3 571.9 361.9 247.9 259.2 611.5 257.2 401.0 365.0 383.9 899.0 298.8 401.5 379.2 262.0 229.7 256.9 312.3 737.4 351.1 344.5 258.1 241.4 386.2 644.2 345.4 416.8 515.2 255.1 375.7 411.3 72.3 513.1 488.6 62.2 205.5 334.3 482.4 247.0 360.5 375.0 110.0 254.9 315.6 672.8 91.1 346.4 510.9 295.6 262.6 675.6 847.9 736.7 1666.7 2577.0 1492.3 641.9 1570.3 2108.3 1248.7 1472.3 1242.6 1223.1 653.6 1227.4 2513.0 1235.3 1067.7 1384.6 1080.4 641.1 406.2 491.0 914.5 915.3 1643.7 2682.9 915.0 778.1 1374.2 1149.4 725.9 1751.3 1516.7 1539.2 301.1 645.9 2174.7 966.0 1102.6 280.6 1404.9 625.1 1879.0 529.5 520.6 784.1 3347.9 1312.7 1062.6 410.5 647.7 726.0 1224.5 1194.2 1086.0 727.6 2767.0 927.6 1213.7 975.8 679.2 1079.4 1152.5 1269.5 693.4 1129.0 1478.0 1238.2 716.7 712.5 491.7 929.6 547.3 931.8 827.8 645.0 762.4 930.9 541.4 411.3 558.0 347.5 668.1 369.3 2643.5 569.3 1512.3 230.7 240.3 247.9 259.2 229.7 256.9 258.1 241.4 255.1 247.0 254.9 262.6 389.3 125.0 209.0 16.6 375.3 160.2 426.2 614.6 234.5 34.5 264.3 303.8 0.8 270.2 328.7 272.2 31.3 625.9 560.0 271.0 90.1 665.1 19.0 295.8 910.1 285.0 297.0 172.6 10.2 566.4 1473.7 627.8 441.4 494.2 181.2 540.4 322.7 473.2 630.1 45.4 15.8 603.9 205.4 216.9 333.4 29.5 456.3 316.6 281.1 19.7 299.1 149.1 368.7 35.2 37.0 435.1 338.9 393.1 2242.6 569.3 338.6 287.4 168.2 43.7 230.1 204.3 445.6 38.4 76.6 337.0 144.8 1118.9 352.3 674.0 477.2 422.3 PPY PNP ENSG00000108849 "Pancreatic polypeptide" P01298 17 43940804-43942476 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "pancreas: 174.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 40.5;Langerhans cells: 10.0;Pancreatic endocrine cells: 33.3" "Cancer enriched" "Detected in some" 132 "pancreatic cancer: 630.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 1.2" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.2" "Cell line enhanced" "Detected in some" "BEWO: 3.7;EFO-21: 3.2;U-2 OS: 3.9" "CAB016735, HPA032122" Enhanced "Secreted to blood" NA NA 70300 44000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB016735: , HPA032122: AB_2674164" "unprognostic (5.12e-3)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.65e-2)" "unprognostic (7.56e-3)" "unprognostic (8.13e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.42e-1)" 0.1 0.3 0.0 0.2 0.0 2.1 0.0 0.0 0.1 0.0 0.0 2.5 1.1 0.3 4.2 0.0 0.1 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.0 174.4 6.9 0.0 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.0 6.7 0.6 0.0 0.0 0.1 0.9 0.3 0.0 0.5 1.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.7 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.5 0.0 3.9 0.4 0.5 0.0 0.3 0.9 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.1 0.0 0.0 40.5 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 10.0 2.8 0.0 0.6 1.8 0.0 0.2 0.0 0.0 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.5 0.0 0.0 0.3 0.0 PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.6" "Cell type enhanced" "Detected in all" "Late spermatids: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA051066: AB_2681333" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (3.93e-2)" "unprognostic (8.54e-2)" "unprognostic (9.08e-3)" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-3)" "unprognostic (9.99e-3)" "unprognostic (3.56e-2)" "unprognostic (2.96e-1)" "unprognostic (4.89e-1)" "unprognostic (1.93e-1)" "unprognostic (9.23e-2)" 22.8 35.9 46.0 9.8 48.1 8.7 19.3 48.6 50.6 15.1 54.1 29.0 25.2 12.6 16.3 25.8 11.3 9.8 101.4 45.8 46.9 27.0 71.5 12.7 9.2 47.6 47.3 11.0 41.6 21.2 23.1 8.2 47.4 19.3 21.4 15.5 29.1 14.7 126.6 20.6 22.1 14.8 46.7 23.6 27.1 31.3 49.0 11.0 17.9 107.1 9.9 23.1 16.3 46.4 21.7 16.6 16.2 31.3 49.3 19.2 22.6 37.8 15.1 32.5 18.7 46.6 20.6 23.3 20.2 38.0 29.3 19.5 25.8 22.7 23.0 36.2 28.2 36.7 21.4 35.2 15.3 20.3 33.7 25.0 13.5 29.2 15.4 9.4 30.5 39.0 32.4 46.1 37.8 41.9 51.7 34.0 5.2 93.7 74.2 31.0 68.6 71.8 18.6 19.0 34.5 12.3 18.1 42.5 15.7 17.3 22.5 15.7 18.9 37.6 16.6 32.9 31.8 52.2 43.9 22.3 24.0 39.6 15.7 15.6 35.0 35.4 24.8 84.3 20.1 17.5 23.8 23.6 36.3 21.8 22.3 19.5 5.0 39.2 105.3 73.3 31.1 48.2 46.0 48.1 48.6 50.6 45.8 46.9 47.6 47.3 47.4 46.7 49.0 46.4 21.7 9.6 4.6 10.1 11.0 15.6 11.3 34.5 4.6 15.2 23.3 23.9 62.6 15.7 20.0 14.7 8.4 25.7 25.4 44.7 72.4 23.3 57.3 12.1 9.3 17.7 32.3 4.2 6.9 46.9 47.2 20.4 13.7 6.0 28.6 4.8 30.7 63.0 49.1 11.8 6.9 47.7 44.7 25.5 14.0 144.3 16.8 19.3 16.0 1.9 7.2 31.4 21.6 6.0 7.0 23.2 31.2 16.1 29.2 10.7 101.4 65.2 15.8 28.3 32.9 19.1 19.1 61.5 21.1 30.1 24.0 13.5 9.7 27.2 50.2 15.4 PRAP1 UPA ENSG00000165828 "Proline rich acidic protein 1" Q96NZ9 10 133347368-133352683 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 1135.4;liver: 675.2" "Cell type enriched" "Detected in some" 9 "Proximal enterocytes: 17736.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 348.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 34.2;Hep G2: 128.3" "HPA038713, HPA052451" Supported "Secreted to digestive system" NA NA 210000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA038713: AB_10673117, HPA052451: AB_2681839" "unprognostic (1.63e-3)" "unprognostic (1.79e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (8.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (4.35e-3)" "unprognostic (4.91e-2)" "unprognostic (8.23e-3)" "unprognostic (2.25e-1)" "unprognostic (3.15e-1)" "unprognostic (2.92e-2)" "unprognostic (2.22e-3)" 0.6 0.5 0.7 4.2 0.7 0.5 0.3 0.4 0.7 0.2 6.5 74.6 1053.8 0.8 0.1 0.4 0.7 2.6 0.3 0.6 0.4 145.4 675.2 0.2 1.5 1.2 0.7 0.4 0.1 0.1 0.8 0.1 1.1 0.3 35.7 0.0 1.7 0.3 0.2 1.3 1135.4 1.7 0.4 0.8 2.7 12.2 0.6 0.3 0.2 0.3 0.1 0.3 0.2 0.8 0.2 0.5 0.1 1.2 0.1 0.0 14.6 0.0 0.0 0.0 0.0 34.2 0.6 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.5 128.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.6 0.0 3.5 0.4 5.0 0.0 0.2 0.9 2.9 0.0 0.0 0.9 4.6 0.4 0.0 0.0 0.8 0.0 0.2 0.0 0.0 1.4 1.3 0.0 1.4 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.7 0.4 0.7 0.6 0.4 1.2 0.7 1.1 0.4 0.6 0.8 0.0 0.0 0.0 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 8.6 0.0 9.2 0.0 0.2 0.0 773.7 33.2 0.1 1.9 0.6 0.0 0.6 18.4 13.5 0.1 0.2 0.2 0.2 1.5 0.1 8.9 0.0 12.5 1021.3 0.2 0.0 0.0 676.2 0.0 20.9 0.0 7.3 1.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1815.7 1.5 0.0 0.1 17736.9 412.0 0.1 0.0 0.0 0.0 0.1 140.2 38.2 0.0 0.0 0.3 3.5 0.0 607.1 0.1 PRB1 "PM, PMF, PMS, PRB1L, PRB1M" ENSG00000251655 "Proline rich protein BstNI subfamily 1" 12 11351823-11395566 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 2529 "salivary gland: 16328.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" 0.0 0.0 0.1 0.0 0.3 2.4 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 6.4 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16328.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRB2 "cP7, PRPPRB1, Ps" ENSG00000121335 "Proline rich protein BstNI subfamily 2" P02812 12 11391540-11501041 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 952 "salivary gland: 12081.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 25000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.36e-1)" "unprognostic (1.01e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-2)" "unprognostic (9.21e-2)" "unprognostic (5.51e-3)" "unprognostic (1.97e-4)" "unprognostic (1.51e-1)" 0.0 0.0 1.9 0.0 5.8 1.6 0.0 0.3 7.4 0.1 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.4 0.0 0.0 0.3 0.0 1.4 1.4 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 12081.4 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.6 1.9 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.8 0.3 7.4 6.1 0.4 1.4 1.4 1.2 0.1 1.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRB3 PRG ENSG00000197870 "Proline rich protein BstNI subfamily 3" Q04118 12 11265924-11269805 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1919 "salivary gland: 14225.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.8;Endometrial ciliated cells: 1.7;Glandular and luminal cells: 1.7;Late spermatids: 3.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 2.2" "Secreted to digestive system" NA NA 27000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.12e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-1)" "unprognostic (7.46e-3)" "unprognostic (4.12e-2)" "unprognostic (9.65e-2)" "unprognostic (1.94e-2)" "unprognostic (8.27e-2)" "unprognostic (9.98e-2)" "unprognostic (2.35e-1)" "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 14225.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.8 1.7 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 PRB4 ENSG00000230657 "Proline rich protein BstNI subfamily 4" 12 11307077-11310436 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 206 "salivary gland: 3664.2" "Cell type enhanced" "Detected in single" "Early spermatids: 1.9" "Group enriched" "Detected in some" 10 "lung cancer: 2.0;melanoma: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.05e-1)" "unprognostic (8.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3664.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 206.6;Leydig cells: 100.6;Melanocytes: 192.1;Muller glia cells: 152.4;Peritubular cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 18.0;BJ: 7.7;fHDF/TERT166: 11.7;SuSa: 5.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" 114.8 23.4 12.6 4.2 14.2 0.5 77.5 7.7 20.2 126.7 20.0 136.4 6.6 147.7 7.6 41.3 108.6 40.4 212.0 11.6 10.0 25.3 15.6 124.7 8.0 10.2 8.2 128.2 13.1 2.5 22.6 12.0 9.4 73.6 8.9 21.5 32.7 77.1 35.6 56.4 61.0 51.4 8.3 44.2 41.3 7.2 10.3 3.2 60.4 36.9 15.9 147.8 92.9 9.4 0.2 0.2 0.5 0.1 18.0 0.5 0.4 7.7 1.0 0.2 0.2 0.0 0.1 1.2 0.6 11.7 0.1 0.6 0.2 0.3 0.3 0.0 0.1 0.2 0.5 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.2 2.1 0.0 0.4 0.2 0.4 1.3 0.1 0.1 0.5 0.4 0.3 0.1 0.4 0.2 0.4 0.0 0.3 1.0 0.2 0.2 0.2 0.8 5.2 0.2 0.1 0.6 0.5 0.2 0.3 0.1 0.2 0.3 1.2 0.1 0.2 0.5 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 12.6 14.2 7.7 20.2 11.6 10.0 10.2 8.2 9.4 8.3 10.3 9.4 8.8 0.0 5.8 5.2 0.9 18.2 1.0 0.0 2.2 3.6 4.2 5.1 7.4 1.5 0.6 0.0 2.1 0.1 0.3 0.1 0.0 0.0 1.1 0.6 1.7 15.6 0.0 2.7 1.6 0.0 0.1 206.6 4.6 1.6 5.1 0.2 22.9 0.3 0.3 1.7 0.2 0.0 0.0 0.3 19.2 5.3 100.6 0.9 192.1 22.5 0.0 152.4 0.0 7.5 0.5 0.0 0.0 199.7 0.4 0.6 0.0 0.1 1.5 8.9 26.3 9.6 38.3 3.1 2.4 1.6 9.9 0.3 1.6 0.1 0.0 1.3 PRG2 "BMPG, MBP, proMBP" ENSG00000186652 "Proteoglycan 2, pro eosinophil major basic protein" P13727 11 57386780-57390650 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Immunity "Antibiotic, Antimicrobial, Heparin-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 2616.3" "Group enriched" "Detected in some" 10 "Erythroid cells: 44.3;Extravillous trophoblasts: 107.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 36 "basophil: 7.2" "Lineage enriched" "Detected in single" 73 "granulocytes: 7.2" "Group enriched" "Detected in some" 62 "HL-60: 3328.5;HMC-1: 5009.7;NB-4: 10560.9" "Not detected" "Not detected" HPA038515 Supported "Secreted in female reproductive system" NA NA 100000000 "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 24: NB-4 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA038515: AB_10675800" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (3.39e-2)" "unprognostic (3.49e-1)" "unprognostic (8.62e-4)" "unprognostic (4.77e-3)" "unprognostic (3.20e-2)" "unprognostic (4.17e-2)" "unprognostic (2.26e-2)" "unprognostic (5.19e-3)" "unprognostic (2.17e-1)" "unprognostic (1.40e-11)" "unprognostic (4.26e-2)" "unprognostic (4.52e-3)" "unprognostic (6.47e-2)" "unprognostic (2.32e-1)" 0.7 0.0 0.0 0.1 0.0 215.8 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 2.5 1.1 1.4 0.0 0.0 0.3 3.8 0.0 0.2 2616.3 0.0 0.0 0.4 0.0 0.9 0.0 0.2 2.1 0.4 0.5 0.0 3.0 0.3 0.0 0.0 8.7 0.2 0.0 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 101.3 0.0 0.0 0.2 3328.5 5009.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 9.0 0.6 0.0 0.0 0.8 10560.9 0.0 0.0 0.0 0.3 0.8 1.0 0.0 0.0 1.6 4.2 0.4 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.4 0.2 0.4 0.3 7.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 44.3 0.0 0.0 107.2 0.5 0.0 0.0 6.3 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 PRG3 "MBP2, MBPH" ENSG00000156575 "Proteoglycan 3, pro eosinophil major basic protein 2" Q9Y2Y8 11 57376769-57381150 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "bone marrow: 48.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 46 "HMC-1: 198.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 3.5" HPA064183 Enhanced "Secreted in other tissues" NA NA 680000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "HPA064183: AB_2685205" 0.0 0.0 0.0 0.0 0.0 48.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 198.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 93.2;liver: 185.7" "Group enriched" "Detected in some" 15 "Fibroblasts: 320.6;Hepatocytes: 364.7" "Cancer enriched" "Detected in many" 10 "liver cancer: 28.4" "Region enriched" "Detected in single" 33 "hypothalamus: 30.8" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cell line enriched" "Detected in some" 6 "ASC diff: 284.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" NA NA 4300000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB054258: " "unprognostic (8.67e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-3)" "unprognostic (1.98e-1)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (4.11e-1)" "unprognostic (1.91e-13)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (1.60e-3)" "unprognostic (7.05e-3)" 93.2 2.3 0.0 2.3 0.0 0.3 15.1 0.4 0.9 0.6 3.9 1.2 0.0 0.6 0.9 0.3 20.0 0.4 31.7 0.0 30.8 0.2 185.7 26.4 0.4 0.0 0.0 2.1 1.5 0.0 2.1 0.0 0.1 0.6 0.1 0.1 3.9 0.1 9.5 7.7 0.4 0.3 0.2 0.7 1.4 0.2 0.2 0.3 1.7 8.1 0.3 2.6 0.5 0.0 0.0 0.1 0.0 0.0 284.6 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 1.1 0.1 0.2 0.2 0.0 26.2 0.0 44.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.7 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.9 0.0 30.8 0.0 0.0 0.1 0.2 0.2 0.0 5.1 22.4 16.2 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 2.7 10.0 21.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.2 3.7 4.1 0.0 2.7 0.0 0.0 0.0 320.6 0.0 0.8 16.4 0.0 6.4 364.7 0.1 0.0 0.1 0.0 0.0 9.4 1.9 0.8 0.0 2.8 1.8 0.0 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 0.1 0.0 0.0 10.9 0.0 0.0 3.5 1.5 0.0 0.3 0.0 1.1 0.0 2.3 0.1 0.0 0.1 PRH2 Pr ENSG00000134551 "Proline rich protein HaeIII subfamily 2" P02810 12 10929236-10934845 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 909 "salivary gland: 23048.6" "Group enriched" "Detected in some" 107 "Early spermatids: 35.5;Late spermatids: 136.2" "Cancer enriched" "Detected in some" 11 "head and neck cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 21000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (3.65e-2)" "unprognostic (3.59e-1)" "unprognostic (1.25e-1)" "unprognostic (5.52e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.01e-2)" "unprognostic (7.37e-2)" "unprognostic (1.63e-5)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (4.26e-1)" "unprognostic (3.43e-2)" 0.0 0.1 0.5 0.0 0.9 1.7 0.1 1.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 19.2 0.0 0.0 4.6 0.6 0.8 0.0 0.4 4.9 0.0 1.2 0.7 4.4 25.3 0.0 0.3 2.6 1.2 0.1 0.0 0.6 23048.6 0.0 0.0 0.9 0.0 0.0 0.5 0.1 0.0 3.9 0.8 0.0 0.1 0.0 0.1 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 1.0 1.0 0.6 0.8 1.2 0.7 1.2 0.5 0.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 35.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 136.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRL ENSG00000172179 Prolactin P01236 6 22287244-22302826 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Lactation Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1022 "pituitary gland: 37505.3" "Group enriched" "Detected in some" 5 "Early spermatids: 13.8;Late spermatids: 28.4;Rod photoreceptor cells: 14.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 31.0;SCLC-21H: 8.9;U-937: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB023353, HPA042416, HPA062017" Enhanced "Secreted to blood" NA NA 53900000 7200000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "CAB023353: AB_617369, HPA042416: AB_2677987, HPA062017: AB_2684660" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (5.89e-3)" "unprognostic (4.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.11e-4)" "unprognostic (4.54e-1)" "unprognostic (1.57e-1)" "unprognostic (3.79e-2)" "unprognostic (4.29e-5)" "unprognostic (2.20e-1)" 3.2 11.2 0.3 1.4 0.0 0.0 1.2 0.6 0.1 0.8 0.1 2.7 0.1 11.5 0.0 11.7 1.6 0.1 4.6 0.0 0.2 2.4 9.6 2.1 0.0 0.9 0.7 4.0 5.5 0.0 37505.3 36.6 1.1 2.3 0.0 33.7 3.6 0.0 2.4 7.7 2.5 2.2 0.0 4.0 19.3 4.0 1.0 4.0 14.2 0.0 0.0 0.4 1.6 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.1 0.4 0.0 0.2 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.2 0.9 0.7 1.1 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.0 13.8 0.1 3.5 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.3 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.5 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRLH PRH ENSG00000071677 "Prolactin releasing hormone" P81277 2 237566574-237567175 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 22.8" "Cell type enhanced" "Detected in single" "Endometrial ciliated cells: 1.0" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Region enhanced" "Detected in many" "medulla oblongata: 22.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.3;MCF7: 1.8;RPMI-8226: 1.4" "Group enriched" "Detected in some" 58 "hypothalamus: 11.3;pons and medulla: 21.5" "Region enriched" "Detected in single" 14 "medulla oblongata: 5.5" HPA014976 Uncertain "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA014976: AB_2732413" "unprognostic (8.28e-4)" "unprognostic (3.22e-2)" "unprognostic (5.42e-2)" 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 1.2 0.0 0.0 0.1 0.0 22.8 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 8.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.2 22.8 0.1 0.5 5.0 0.9 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 PROK1 "EGVEGF, PK1, PRK1" ENSG00000143125 "Prokineticin 1" P58294 1 110451149-110457358 "Predicted secreted proteins" Angiogenesis "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "ovary: 197.1;placenta: 50.2;testis: 59.1" "Group enriched" "Detected in some" 8 "Leydig cells: 173.1;Peritubular cells: 668.0" "Cancer enhanced" "Detected in many" "testis cancer: 4.7" "Region enhanced" "Detected in many" "medulla oblongata: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "ASC diff: 22.6" "Region enriched" "Detected in single" 11 "pons and medulla: 1.4" "Low region specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "unprognostic (2.66e-1)" "unprognostic (2.71e-2)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.26e-1)" "unprognostic (1.86e-1)" "unprognostic (3.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-2)" "unprognostic (7.39e-3)" "unprognostic (1.90e-1)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" 4.0 9.8 0.4 0.4 0.3 0.0 5.1 0.4 0.7 14.1 0.2 0.3 0.1 0.3 0.1 1.2 3.5 0.4 2.7 1.1 0.4 0.1 0.2 0.3 0.0 5.5 1.3 197.1 0.3 0.0 0.7 50.2 1.2 12.8 0.0 0.1 0.5 9.9 1.3 2.4 0.2 0.0 1.8 1.5 0.4 59.1 0.9 0.1 0.2 0.0 0.0 4.5 25.1 1.5 0.0 0.0 0.0 0.1 22.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.7 1.1 0.4 5.5 1.3 1.2 1.8 0.9 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.7 0.6 16.4 0.1 0.0 0.0 0.0 0.0 0.1 5.9 0.0 0.3 0.0 1.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 23.4 173.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 668.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.7 1.1 0.0 0.0 1.0 0.1 52.3 0.0 0.1 PROK2 "BV8, KAL4, MIT1, PK2" ENSG00000163421 "Prokineticin 2" Q9HC23 3 71771655-71785206 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biological rhythms" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 64.5;lymphoid tissue: 22.5" "Cell type enhanced" "Detected in some" "Erythroid cells: 5.9;Kupffer cells: 8.0;Macrophages: 11.3;monocytes: 6.9;Spermatocytes: 23.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.1" "Region enriched" "Detected in many" 7 "cerebral cortex: 13.3" "Immune cell enriched" "Detected in many" 50 "neutrophil: 414.4" "Lineage enriched" "Detected in many" 50 "granulocytes: 414.4" "Cell line enhanced" "Detected in some" "HL-60: 9.2;NB-4: 8.9;NTERA-2: 5.5;U-266/70: 12.0;U-266/84: 20.8;U-937: 8.3" "Group enriched" "Detected in some" 6 "basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA041408 Approved "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA041408: AB_10964057" "unprognostic (5.24e-2)" "unprognostic (3.13e-3)" "unprognostic (3.51e-3)" "unprognostic (3.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.94e-1)" "unprognostic (2.97e-2)" "unprognostic (9.52e-2)" "unprognostic (4.29e-2)" "unprognostic (9.91e-3)" "unprognostic (6.89e-2)" "unprognostic (5.73e-1)" "unprognostic (1.59e-4)" "unprognostic (2.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" 7.2 0.3 0.7 17.7 0.5 64.5 0.3 0.1 13.3 0.4 0.7 0.4 0.3 0.2 0.0 0.4 2.7 1.2 1.0 0.2 0.5 0.6 2.5 13.1 0.2 0.5 1.0 0.2 1.1 0.0 0.4 3.1 1.2 0.2 0.2 0.1 0.3 0.0 0.5 0.1 0.5 1.5 0.2 22.5 0.6 11.4 1.9 1.1 0.5 4.2 0.5 6.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.6 0.0 0.0 0.0 0.3 8.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 20.8 0.0 0.0 8.3 0.0 0.0 8.2 3.5 3.4 0.7 0.0 0.0 2.7 2.9 0.7 0.0 0.9 5.0 414.4 0.0 0.2 0.3 1.7 3.1 0.7 0.5 0.1 13.3 0.2 0.5 0.5 1.0 1.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 1.8 0.0 0.0 2.5 0.0 0.0 0.0 1.6 0.1 0.1 0.1 0.0 5.9 0.0 0.0 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 8.0 0.3 2.8 0.3 11.3 1.8 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 23.8 2.9 0.0 0.0 0.0 3.5 0.1 0.0 0.0 PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 83.1;Hepatocytes: 307.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 112.3;ASC TERT1: 100.1;HSkMC: 78.2;SK-MEL-30: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" 33.6 8.7 1.7 8.1 1.3 0.3 24.7 1.6 2.7 14.9 107.5 17.3 13.5 16.4 2.0 16.6 19.4 33.7 116.6 3.2 2.2 37.7 283.1 39.2 4.7 2.1 2.4 32.6 5.6 13.5 8.5 32.0 2.2 8.4 21.6 4.6 12.3 10.3 4.9 20.5 20.6 19.2 1.6 11.2 10.5 5.0 2.3 1.5 17.0 16.9 3.7 18.5 15.1 1.7 0.4 2.7 3.0 27.1 112.3 100.1 1.6 4.6 9.4 1.0 6.6 12.7 1.4 0.0 30.0 3.0 18.8 0.0 1.4 0.9 1.8 0.1 7.3 51.4 1.4 29.8 8.7 1.5 1.2 78.2 0.4 4.0 0.6 63.0 7.2 3.7 32.8 0.1 49.2 0.0 0.1 0.0 3.1 2.7 6.5 0.3 1.2 0.0 27.7 0.0 7.6 19.8 5.0 0.0 157.0 0.6 0.0 19.9 9.4 14.8 2.8 8.2 1.7 0.0 0.0 0.0 60.4 30.4 27.8 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 3.2 1.7 1.3 1.6 2.7 3.2 2.2 2.1 2.4 2.2 1.6 2.3 1.7 55.9 64.1 33.8 17.9 1.9 14.8 3.6 2.1 4.0 0.5 1.7 14.0 44.6 14.3 7.5 1.8 10.4 0.6 0.5 7.5 3.9 9.8 3.2 2.1 30.7 47.1 15.7 16.4 28.4 4.4 0.7 83.1 2.0 1.1 30.9 5.0 65.7 307.1 12.8 1.7 19.7 11.6 0.0 31.5 20.6 6.3 28.6 14.6 19.6 27.2 1.3 22.8 0.0 10.6 4.6 5.6 19.3 36.9 0.3 4.5 1.9 42.2 56.6 8.1 13.1 32.4 28.4 0.4 0.7 11.8 33.2 1.6 2.1 10.8 12.6 2.3 PROZ PZ ENSG00000126231 "Protein Z, vitamin K dependent plasma glycoprotein" P22891 13 113158648-113172386 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 109.2" "Group enriched" "Detected in some" 52 "Hepatocytes: 63.5;Proximal tubular cells: 20.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.2;Hep G2: 3.6" "Not detected" "Not detected" HPA052006 Supported "Secreted to blood" NA NA 1720000000 650000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA052006: AB_2681691" "unprognostic (5.03e-2)" "unprognostic (4.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (6.48e-2)" "unprognostic (1.39e-1)" "prognostic favorable (3.46e-4)" "unprognostic (4.10e-1)" "unprognostic (2.21e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (2.87e-1)" "unprognostic (9.83e-2)" "unprognostic (5.63e-2)" "unprognostic (1.41e-1)" "unprognostic (9.99e-2)" "unprognostic (2.51e-4)" 0.1 0.3 0.1 0.3 0.0 0.1 0.0 0.7 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 14.4 109.2 0.1 0.3 0.0 0.0 0.1 0.7 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.5 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.6 0.3 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.4 1.1 0.4 1.6 3.6 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.3 0.0 0.5 0.3 0.4 0.8 1.4 0.1 0.6 0.1 0.1 0.0 0.5 1.3 0.0 0.0 0.1 0.6 0.7 0.0 0.4 0.3 0.3 0.0 0.3 0.1 0.7 0.4 0.3 0.7 0.4 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 63.5 0.0 0.0 0.1 0.6 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 20.5 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 PRR27 C4orf40 ENSG00000187533 "Proline rich 27" Q6MZM9 4 70133616-70176799 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 959 "salivary gland: 1106.3" "Group enriched" "Detected in some" 25 "Early spermatids: 25.5;Late spermatids: 9.8" "Cancer enriched" "Detected in single" 10 "breast cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036150, HPA036151" Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA036150: AB_10673001, HPA036151: AB_2674971" "unprognostic (9.52e-2)" 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.3 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1106.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PRR4 "LPRP, PROL4" ENSG00000111215 "Proline rich 4" Q16378 12 10845849-10849475 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "salivary gland: 6616.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 92.8;Cone photoreceptor cells: 139.7;Horizontal cells: 85.8;Rod photoreceptor cells: 119.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "OE19: 2.8" HPA042133 Supported "Secreted to digestive system" NA NA 14000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA042133: AB_10793979" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.35e-2)" "unprognostic (1.74e-2)" "unprognostic (1.99e-1)" "unprognostic (5.03e-2)" "unprognostic (3.01e-3)" "unprognostic (3.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.23e-1)" "unprognostic (3.19e-2)" "unprognostic (1.09e-2)" "unprognostic (3.57e-6)" "unprognostic (2.81e-2)" "unprognostic (9.15e-2)" "unprognostic (1.21e-1)" "unprognostic (2.15e-2)" 1.9 2.0 0.6 0.0 0.6 0.1 9.7 0.6 1.8 0.1 0.6 0.2 7.6 0.0 0.0 148.1 0.0 0.0 0.4 0.6 0.6 0.2 0.2 74.4 0.0 0.8 0.6 0.1 2.7 0.0 2.0 0.1 0.6 4.0 0.0 0.0 6616.8 0.1 0.8 73.4 0.2 0.0 0.6 0.1 66.0 0.5 0.6 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 2.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 1.8 0.6 0.6 0.8 0.6 0.6 0.6 0.6 0.6 0.3 3.2 0.0 0.0 22.0 3.1 6.8 19.9 9.6 92.8 7.5 2.8 1.8 7.2 8.2 1.8 139.7 16.4 20.1 6.3 1.9 0.1 10.2 0.1 0.2 9.6 16.2 14.1 0.0 0.4 2.5 9.3 10.7 0.1 8.9 0.4 14.6 5.9 7.7 85.8 0.0 6.4 24.4 8.7 6.0 13.9 21.8 6.1 28.4 0.0 7.9 18.2 56.7 0.0 0.0 3.4 14.4 24.5 17.1 9.3 7.9 0.2 6.8 119.2 13.1 23.0 7.1 13.5 5.7 8.1 2.3 4.0 20.1 0.5 9.6 4.0 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1923 "pancreas: 341429.7" "Cell type enriched" "Detected in some" 28 "Exocrine glandular cells: 57138.3" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "OE19: 10.6;RPMI-8226: 4.5;U-2 OS: 2.8" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 100000000000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavorable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.12e-1)" 45.2 9.9 0.0 4.7 0.0 0.0 25.7 0.0 0.0 19.9 0.0 11.2 54.5 8.9 0.8 15.2 5.6 0.0 51.0 0.0 0.0 9.6 29.7 6.4 6.5 0.0 0.0 177.5 341429.7 0.1 10.3 13.9 0.0 15.2 0.0 0.0 44.2 4.2 8.9 12.1 12.7 0.0 0.0 13.4 77.1 6.9 0.0 0.0 6.4 0.0 0.0 4.7 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 100.7 0.0 0.1 0.0 3.6 0.0 0.0 0.0 57138.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 119.4 0.6 0.0 0.0 0.0 1985.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.2 0.2 PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Club cells: 34.3;Cytotrophoblasts: 48.0;Respiratory ciliated cells: 76.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 70.2;SH-SY5Y: 215.4;THP-1: 100.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035054 Uncertain Approved "Nucleoplasm,Actin filaments" "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" Nucleoplasm "HPA035054: AB_10603990" "unprognostic (4.30e-2)" "unprognostic (1.04e-2)" "unprognostic (2.55e-1)" "unprognostic (4.41e-2)" "prognostic favorable (2.66e-4)" "prognostic favorable (1.03e-4)" "unprognostic (4.21e-1)" "unprognostic (3.48e-2)" "unprognostic (7.83e-2)" "unprognostic (6.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (9.55e-2)" "unprognostic (1.09e-1)" 0.6 0.5 1.4 1.6 0.9 0.1 2.2 0.6 1.3 14.5 14.4 6.7 2.7 1.9 0.6 3.2 10.5 9.8 0.0 2.7 0.5 0.8 0.6 7.6 0.1 0.5 1.9 1.6 7.7 0.1 0.6 10.6 0.7 1.4 6.4 0.3 2.5 2.0 0.2 5.9 4.8 1.3 0.5 0.0 9.2 10.0 1.2 1.0 0.2 1.2 5.7 3.8 12.6 0.5 5.2 0.2 1.8 0.0 0.2 13.3 0.1 46.0 41.5 9.7 16.1 0.1 18.7 0.0 0.2 70.2 4.9 0.8 31.1 9.5 12.7 0.2 7.2 0.0 3.6 0.0 1.4 0.0 0.2 4.1 17.5 3.4 9.9 31.2 0.1 0.6 0.0 0.0 8.0 0.3 0.5 9.6 2.2 36.4 2.9 0.0 38.7 0.0 0.0 7.0 5.1 215.4 0.0 0.2 3.0 30.9 0.0 100.6 0.0 19.2 2.8 12.2 9.1 1.0 0.1 0.0 1.0 3.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.6 1.3 2.7 0.5 0.5 1.9 0.7 0.5 1.2 0.5 0.3 6.4 4.6 0.7 0.2 8.4 0.8 16.4 2.2 0.6 0.8 0.8 1.4 10.0 34.3 1.8 0.0 48.0 0.0 26.8 0.0 0.4 9.9 19.7 16.8 0.9 5.3 0.0 10.5 10.2 4.5 7.1 17.9 2.6 7.0 3.3 0.0 0.4 3.8 0.0 14.3 2.7 10.2 0.0 4.2 18.3 0.0 0.4 5.4 7.5 0.0 0.0 0.0 0.5 0.2 8.1 12.8 0.0 0.2 0.4 9.4 0.6 76.1 0.2 0.0 0.6 4.9 10.1 13.3 3.6 4.3 11.9 0.7 21.8 5.3 4.7 PRSS16 TSSP ENSG00000112812 "Serine protease 16" Q9NQE7 6 27247701-27256624 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 58 "lymphoid tissue: 826.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 42.1;Extravillous trophoblasts: 25.4;Syncytiotrophoblasts: 31.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.1" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "hTCEpi: 20.4;RPMI-8226: 11.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.50e-1)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.74e-2)" "unprognostic (9.21e-3)" "unprognostic (1.57e-1)" "unprognostic (7.89e-2)" "prognostic favorable (6.46e-5)" "unprognostic (1.57e-1)" "unprognostic (3.49e-2)" "unprognostic (5.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.62e-2)" 0.2 0.4 0.0 0.3 0.0 0.0 6.0 0.1 0.3 3.6 0.0 5.7 4.4 0.7 13.5 2.9 5.6 4.0 0.0 0.1 0.0 1.8 0.0 3.8 0.1 0.0 0.0 2.5 14.1 7.8 1.4 4.1 0.1 3.2 6.7 0.1 7.5 4.2 0.0 5.1 3.3 0.2 0.0 0.3 4.8 1.0 0.0 826.7 13.1 0.0 1.4 2.5 1.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.1 3.8 4.7 0.0 0.7 0.0 0.0 1.5 2.7 3.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 2.1 0.5 0.0 20.4 0.0 4.1 0.5 0.0 1.7 2.5 1.9 0.0 1.2 0.5 0.0 0.7 2.1 0.5 0.0 0.0 11.5 2.4 3.6 0.0 0.0 1.4 3.2 0.0 4.5 2.0 0.9 0.0 0.0 0.7 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.7 2.1 0.9 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 9.6 7.7 0.0 2.6 6.4 10.8 4.6 8.6 0.0 16.6 9.5 0.4 15.7 4.6 14.7 0.0 42.1 0.2 22.9 1.9 10.0 0.6 2.5 0.8 0.4 4.2 0.0 0.7 17.6 25.4 0.7 12.8 8.0 5.7 0.1 0.0 0.0 4.0 0.0 0.2 20.0 14.2 0.3 0.4 0.5 0.6 0.3 5.4 0.0 0.2 1.2 0.0 0.0 0.1 9.4 18.7 0.0 13.7 6.9 16.5 0.7 3.4 0.0 0.0 0.0 1.2 2.0 6.1 8.6 6.5 31.7 1.1 0.0 14.9 8.5 PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 452 "pancreas: 239420.0" "Cell type enriched" "Detected in some" 11 "Exocrine glandular cells: 108258.7" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 4.1;T-reg: 2.9" "Group enriched" "Detected in many" 8 "granulocytes: 4.1;T-cells: 2.9" "Cell line enhanced" "Detected in some" "OE19: 21.0;RPMI-8226: 67.5;U-2 OS: 15.2" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 890000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "prognostic favorable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" 65.1 12.5 0.1 0.2 0.1 3.2 25.4 0.0 0.1 27.6 0.0 12.6 358.5 11.4 0.0 18.2 9.6 0.1 25.0 0.0 0.0 9.4 32.2 8.2 1.3 0.0 0.0 64.9 239420.0 0.0 13.4 8.1 0.0 17.2 0.0 0.0 25.4 0.9 10.1 11.3 529.2 0.1 0.0 16.9 54.7 8.6 0.0 0.9 8.3 0.0 0.0 7.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.4 4.4 0.5 0.0 0.0 0.0 1.9 0.0 21.0 0.0 0.0 0.0 67.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.9 3.8 0.0 2.9 0.6 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 378.7 0.0 0.4 0.1 11.4 0.0 0.0 0.0 108258.7 0.0 0.3 4.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 348.9 0.0 0.0 0.0 0.0 9565.7 8.9 0.0 0.1 0.0 60.0 0.1 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 85.4 0.2 PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 79.6;salivary gland: 26.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 221.0;Club cells: 343.9;Ionocytes: 207.5;Pancreatic endocrine cells: 380.6;Urothelial cells: 479.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 17.3;MCF7: 14.6;RT4: 10.4;SK-BR-3: 22.9" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 23.4 0.0 0.5 0.3 0.7 0.4 79.6 1.3 0.8 0.0 0.0 0.0 16.7 0.5 2.9 0.0 0.0 0.0 0.0 5.8 1.5 2.4 1.1 0.0 6.0 0.5 0.0 26.9 0.3 0.0 3.2 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.3 0.0 2.2 2.5 23.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.3 17.3 0.0 0.0 0.0 0.0 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 22.9 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 4.2 0.0 0.2 23.2 221.0 128.8 28.5 0.0 42.8 23.7 0.3 38.6 343.9 16.5 0.0 36.7 1.9 18.5 1.9 113.1 0.0 28.4 4.6 1.8 3.6 0.0 0.0 98.3 37.1 1.3 52.5 56.6 0.0 0.0 0.0 0.1 2.3 0.0 0.0 7.5 207.5 0.0 1.4 0.0 0.0 0.9 7.2 0.0 1.0 0.0 0.0 0.0 0.0 380.6 32.3 0.0 0.3 75.4 0.6 0.2 108.0 0.0 0.0 0.0 13.7 0.1 0.2 22.7 27.6 10.5 2.7 0.0 6.9 479.5 PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 249.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.1;Endothelial cells: 502.1;Granulosa cells: 347.3;Hepatic stellate cells: 591.8;Theca cells: 445.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 104.6" "Group enriched" "Detected in many" 25 "NK-cells: 34.2;T-cells: 104.6" "Cell line enhanced" "Detected in many" "GAMG: 1093.7;hTERT-RPE1: 1296.9;TIME: 1138.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030591 Uncertain "Secreted to blood" NA NA 440000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA030591: AB_10602067" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "prognostic unfavorable (2.12e-4)" "unprognostic (1.89e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (5.56e-4)" "unprognostic (5.35e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.13e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (8.01e-2)" 55.0 21.4 7.8 35.3 7.8 2.1 43.2 7.1 8.7 249.1 12.9 103.6 19.2 103.4 13.4 22.1 24.9 83.8 28.3 7.9 8.0 42.4 15.0 63.3 21.8 14.0 13.9 26.8 29.8 36.0 16.4 61.7 8.8 61.3 50.3 2.7 52.4 128.2 79.6 19.4 29.0 115.5 7.1 18.0 54.2 31.8 14.1 17.5 40.9 18.7 10.2 99.6 79.1 7.4 62.7 153.3 161.1 1.0 70.4 172.3 0.7 269.0 244.4 293.2 232.6 368.1 484.7 0.2 208.2 414.7 1093.7 126.2 2.6 205.0 70.9 0.7 13.0 21.1 74.7 1.4 36.3 0.1 0.9 137.4 26.8 143.2 162.1 1296.9 604.8 0.9 1.3 0.3 223.4 87.7 0.2 0.3 9.8 211.7 16.8 0.0 0.0 0.7 111.5 82.3 1.5 1.0 59.9 4.5 18.7 397.6 6.0 0.6 1138.2 174.0 2.3 351.7 154.5 1.3 1.3 0.8 124.2 0.5 176.3 0.2 0.2 0.1 104.6 0.1 0.2 0.2 17.8 60.0 0.2 0.0 4.7 50.4 1.6 34.2 2.7 0.2 0.0 39.9 7.8 7.8 7.1 8.7 7.9 8.0 14.0 13.9 8.8 7.1 14.1 7.4 95.8 28.9 14.5 14.0 3.2 15.4 96.2 367.1 2.8 1.6 44.7 78.0 4.3 37.1 231.3 53.3 2.1 18.4 53.4 154.8 7.9 162.6 3.1 10.3 130.3 502.1 13.8 20.4 26.3 83.5 15.7 117.1 22.4 7.0 2.5 347.3 591.8 5.2 5.0 0.0 16.5 30.6 85.5 36.6 18.2 6.6 14.3 5.4 72.9 39.4 1.5 0.8 180.2 11.6 2.3 257.7 80.1 7.5 5.8 100.1 5.2 5.7 90.1 0.9 39.5 14.4 105.9 3.0 7.3 1.7 9.8 4.5 24.0 445.1 11.1 60.2 PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.5;esophagus: 388.6;vagina: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Horizontal cells: 11.8;Squamous epithelial cells: 9.6;Urothelial cells: 11.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.1;SK-BR-3: 24.4;T-47d: 14.6;U-266/70: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" NA NA 8700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" 1.0 0.4 0.9 0.2 0.9 0.3 1.3 1.0 2.0 83.5 0.6 1.0 0.0 1.0 0.0 388.6 0.7 0.2 0.4 0.8 1.4 1.1 0.6 0.6 0.3 1.2 1.5 0.5 0.8 0.7 1.5 0.1 1.0 1.0 0.0 0.2 52.5 0.4 0.3 3.3 0.6 0.0 1.0 0.6 0.8 2.6 1.2 0.6 0.8 0.0 29.9 0.8 134.2 0.9 0.1 0.3 0.4 2.1 0.3 0.7 6.1 0.0 0.2 0.2 0.2 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.5 0.1 0.1 0.0 1.0 0.0 0.3 1.2 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.6 0.0 2.0 0.0 1.1 1.4 0.2 0.0 1.0 0.2 0.1 0.2 0.3 0.7 2.8 0.0 24.4 0.6 0.1 14.6 1.8 0.0 0.4 0.0 0.1 0.0 5.2 3.7 0.5 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.9 1.0 2.0 0.8 1.4 1.2 1.5 1.0 1.0 1.2 0.9 1.5 9.6 5.8 0.0 0.5 1.8 2.5 1.3 0.6 5.2 5.1 6.2 1.2 1.5 5.6 1.8 4.2 0.7 0.5 1.2 0.0 1.5 3.3 0.6 1.4 1.8 0.0 0.0 0.4 1.4 0.6 1.4 1.1 1.6 3.8 1.1 0.4 0.7 0.3 11.8 0.8 0.5 0.0 0.3 3.1 1.0 0.3 0.8 1.8 1.9 0.9 2.6 0.0 0.0 0.3 1.1 1.2 0.0 0.2 1.7 0.1 0.7 3.4 6.6 0.0 2.7 1.5 3.0 3.9 9.6 2.4 3.3 1.3 0.6 1.4 11.1 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 268 "pancreas: 31113.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1022.9;Exocrine glandular cells: 2040.4;Pancreatic endocrine cells: 478.8;Paneth cells: 969.9;Proximal enterocytes: 1127.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 158.7" "Lineage enriched" "Detected in many" 104 "granulocytes: 158.7" "Group enriched" "Detected in many" 5 "OE19: 316.6;PC-3: 852.5" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 700000000 "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 3.8 4.6 23.5 7.2 29.3 0.6 1.7 25.8 35.4 30.8 16.9 87.0 92.6 0.4 0.0 116.2 0.3 22.8 6.3 28.2 25.6 3.7 12.4 0.6 0.7 25.0 24.5 12.9 31113.6 0.0 0.7 1.7 25.7 1.1 77.8 0.3 20.9 0.3 0.5 79.7 105.4 3.1 19.4 0.7 22.8 5.1 25.6 0.8 0.4 0.0 15.2 4.2 56.9 24.7 12.0 13.7 0.7 0.0 0.2 5.9 0.1 33.6 7.7 4.1 1.6 34.3 3.0 0.0 0.2 14.9 0.2 15.0 0.0 31.7 10.1 0.4 0.2 0.0 1.1 0.0 2.7 0.0 0.0 0.2 0.0 10.8 110.2 0.3 68.8 0.2 0.0 0.0 0.0 0.2 0.7 0.4 0.2 316.6 852.5 0.0 0.0 0.0 0.0 1.7 0.3 81.2 0.2 0.0 0.0 0.5 0.0 0.0 78.3 0.0 0.0 12.8 0.0 0.0 0.0 0.1 18.1 0.0 0.1 158.7 0.0 0.0 0.2 1.5 1.2 0.0 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.3 23.5 29.3 25.8 35.4 28.2 25.6 25.0 24.5 25.7 19.4 25.6 24.7 0.1 0.0 0.0 0.7 1.9 57.1 0.6 1.3 0.0 0.2 0.1 2.8 1.0 47.1 1.2 1.8 0.0 0.0 0.1 1022.9 3.9 43.2 31.4 0.0 0.0 3.2 192.6 0.0 32.8 2040.4 0.0 0.8 39.3 0.0 8.9 0.0 0.7 4.2 0.0 0.0 4.7 146.4 0.0 0.3 12.1 79.7 1.5 1.2 7.2 3.7 5.7 0.0 0.0 3.5 1.2 478.8 969.9 0.7 0.3 12.1 1127.1 14.7 0.1 0.2 0.0 0.0 1.7 0.5 0.9 1.1 134.1 0.1 2.1 0.0 329.0 56.2 PRSS33 EOS ENSG00000103355 "Serine protease 33" Q8NF86 16 2783953-2787948 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "fallopian tube: 4.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Melanocytes: 1.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 65 "eosinophil: 1296.1" "Lineage enriched" "Detected in many" 391 "granulocytes: 1296.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.7;hTERT-RPE1: 5.0;SK-MEL-30: 5.9;U-2 OS: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (4.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.99e-2)" "unprognostic (3.38e-2)" "unprognostic (3.10e-1)" "unprognostic (2.86e-2)" "unprognostic (1.16e-1)" "unprognostic (4.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.42e-2)" "unprognostic (2.28e-1)" "unprognostic (1.91e-1)" "unprognostic (2.70e-2)" 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.9 0.4 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.4 1296.1 0.2 0.4 0.2 0.1 0.1 0.0 0.2 0.2 0.1 0.3 2.1 3.3 0.3 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 36 "Muller glia cells: 410.9" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.4;CACO-2: 86.3;HAP1: 12.8;RPTEC TERT1: 24.6;SuSa: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 1.3 2.4 2.9 0.1 3.8 0.0 0.3 1.7 6.8 2.9 1.5 0.1 0.3 1.3 1.1 0.3 1.4 4.2 4.4 3.2 2.1 3.1 0.4 1.3 0.7 1.8 1.9 10.2 0.3 0.3 1.1 3.6 1.8 1.1 0.3 50.5 0.3 0.4 0.1 0.2 0.1 1.5 1.8 0.7 0.3 3.1 2.6 0.1 0.4 0.1 0.1 1.3 0.5 2.2 0.0 0.5 1.9 0.0 0.1 0.0 0.0 0.3 10.4 1.0 2.0 86.3 0.0 0.0 0.1 0.4 0.0 0.0 12.8 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 3.1 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 0.4 8.2 0.0 0.0 0.0 24.6 0.0 0.0 1.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 19.5 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 3.8 1.7 6.8 3.2 2.1 1.8 1.9 1.8 1.8 2.6 2.2 0.3 3.2 0.5 8.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 1.5 0.0 0.0 1.8 0.0 0.3 0.0 0.1 9.8 0.1 0.1 0.0 0.3 0.8 1.8 0.0 0.2 0.0 0.0 4.4 0.0 0.0 0.0 0.9 0.0 0.3 0.4 6.7 0.2 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 1.0 0.0 410.9 0.0 1.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 11.4 6.6 0.1 3.7 0.1 0.5 0.0 0.0 0.1 0.7 5.1 0.0 0.0 PRSS36 FLJ90661 ENSG00000178226 "Serine protease 36" Q5K4E3 16 31138926-31150083 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 11.7;Distal enterocytes: 13.2;Hofbauer cells: 18.7;Paneth cells: 15.4;Proximal enterocytes: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "HeLa: 2.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA036079 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA036079: AB_10602290" "unprognostic (3.74e-2)" "prognostic favorable (2.97e-7)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (4.26e-3)" "unprognostic (1.31e-5)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (2.65e-2)" "unprognostic (8.03e-2)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (9.86e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-1)" 1.4 0.8 0.4 0.3 0.6 0.4 0.5 0.4 0.8 0.2 0.3 0.7 1.0 0.1 0.0 0.3 0.3 0.1 0.3 0.5 0.5 0.2 0.3 0.7 0.1 0.5 0.4 0.1 0.2 0.1 2.6 0.7 0.5 0.1 0.2 0.0 0.5 0.1 0.2 1.0 0.7 0.3 0.4 0.1 0.3 0.4 0.6 0.8 0.3 0.0 0.2 0.4 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.4 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 1.0 0.1 0.0 0.2 0.0 0.0 0.4 0.6 0.4 0.8 0.5 0.5 0.5 0.4 0.5 0.4 0.6 0.5 0.3 0.0 1.1 0.7 0.2 1.9 2.6 8.9 1.8 0.5 5.9 11.7 1.1 2.8 3.5 0.0 0.0 0.8 1.2 13.2 0.0 1.7 1.7 0.9 0.6 0.6 0.0 0.4 0.6 2.8 1.2 1.3 1.1 0.9 0.0 0.5 3.3 3.3 18.7 0.0 0.8 4.1 2.0 3.2 3.8 0.9 2.8 4.2 0.0 0.0 5.4 0.6 4.1 0.0 0.1 1.8 15.4 2.6 0.0 1.7 46.9 1.9 1.2 0.0 0.0 0.4 0.4 0.6 4.4 1.5 2.6 0.5 0.5 1.1 3.9 1.9 PRSS37 ENSG00000165076 "Serine protease 37" A4D1T9 7 141836300-141841487 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "testis: 41.3" "Group enriched" "Detected in some" 138 "Early spermatids: 612.8;Late spermatids: 325.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA020541 Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA020541: AB_1853004" "unprognostic (4.70e-2)" "unprognostic (5.56e-2)" "unprognostic (2.69e-1)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (1.30e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-2)" "unprognostic (8.30e-7)" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (2.72e-2)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 41.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.7 0.2 0.2 0.1 0.3 0.2 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 612.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 325.7 2.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS38 MPN2 ENSG00000185888 "Serine protease 38" A1L453 1 227815693-227846470 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 28 "testis: 4.2" "Group enriched" "Detected in some" 17 "Spermatocytes: 28.8;Spermatogonia: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "U-266/84: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (9.54e-3)" "unprognostic (3.61e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS48 ESSPL ENSG00000189099 "Serine protease 48" Q7RTY5 4 151277171-151291453 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 18.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 2.2;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 3.7;Sertoli cells: 6.6;Spermatocytes: 3.1;Spermatogonia: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053801 Uncertain "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA053801: AB_2682267" "unprognostic (9.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.76e-2)" "unprognostic (4.10e-2)" 0.0 0.0 1.6 0.0 2.2 0.0 0.0 2.8 1.6 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.8 0.0 0.0 0.0 0.0 2.9 1.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.2 2.8 1.6 1.0 2.8 2.9 1.0 3.4 0.8 1.9 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.1 0.0 3.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS51 ENSG00000253649 "Serine protease 51" A0A1B0GVH4 8 10482878-10547585 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 17 "brain: 22.6" "Group enriched" "Detected in some" 10 "Early spermatids: 3.2;Late spermatids: 3.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 12 "cerebellum: 22.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.52e-1)" "unprognostic (3.00e-1)" "unprognostic (3.10e-1)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-2)" "unprognostic (2.72e-1)" "unprognostic (7.48e-2)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (1.02e-1)" "unprognostic (6.33e-3)" "unprognostic (2.71e-3)" "unprognostic (7.47e-2)" "unprognostic (3.42e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" 0.0 0.1 0.3 0.1 0.5 0.2 1.1 22.6 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.7 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 22.6 1.9 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS53 POL3S ENSG00000151006 "Serine protease 53" Q2L4Q9 16 31083425-31089628 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2;liver: 9.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.3;Inhibitory neurons: 4.3;Oligodendrocytes: 4.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 4.8;U-87 MG: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034955, HPA034956" Uncertain "Secreted in other tissues" NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA034955: AB_2674380, HPA034956: AB_10696365" "unprognostic (3.13e-1)" "unprognostic (4.15e-1)" "unprognostic (3.88e-3)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.63e-2)" "unprognostic (1.04e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.63e-4)" "unprognostic (2.53e-12)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" 0.2 0.1 1.7 0.4 1.9 0.0 0.2 1.9 3.2 0.5 1.5 0.4 0.3 0.3 0.1 0.3 0.1 0.3 0.2 1.8 1.9 0.6 9.9 0.4 0.4 1.8 1.8 0.3 0.6 0.0 0.8 0.1 1.8 0.9 0.1 0.1 0.4 0.2 0.1 2.8 0.4 0.4 1.7 0.5 0.5 0.0 1.8 0.1 0.4 0.0 0.0 0.4 0.5 2.2 0.3 0.4 0.1 0.3 0.0 0.5 0.8 0.4 0.8 0.5 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.7 0.8 0.0 0.4 0.3 1.0 0.0 0.4 0.1 0.9 0.2 1.1 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 4.8 0.3 0.4 0.0 0.4 0.0 0.5 0.2 0.3 0.8 0.5 1.6 0.1 0.7 0.2 0.1 2.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.9 3.2 1.8 1.9 1.8 1.8 1.8 1.7 1.8 2.2 0.2 0.0 0.0 1.6 0.2 0.4 0.2 0.2 0.0 0.4 0.1 0.1 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.4 6.3 0.2 0.2 0.2 1.1 0.3 0.0 0.3 0.4 0.7 0.1 0.0 4.3 0.1 0.0 0.0 0.4 0.2 1.8 0.4 0.0 0.0 0.0 0.1 0.0 0.5 4.4 0.4 0.0 1.2 0.2 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.2 0.1 0.1 0.5 1.4 0.0 1.0 0.1 0.1 0.3 PRSS54 "CT67, FLJ25339, KLKBL4" ENSG00000103023 "Serine protease 54" Q6PEW0 16 58279997-58295047 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 110 "testis: 41.4" "Group enriched" "Detected in some" 34 "Early spermatids: 526.0;Late spermatids: 208.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA041549 Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA041549: AB_10795640" "unprognostic (1.13e-1)" "unprognostic (3.24e-2)" "unprognostic (3.09e-2)" "unprognostic (3.08e-1)" "unprognostic (4.88e-2)" "unprognostic (1.23e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 526.0 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 208.3 5.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS57 "PRSSL1, UNQ782" ENSG00000185198 "Serine protease 57" Q6UWY2 19 685546-695498 "Enzymes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "bone marrow: 165.3" "Cell type enriched" "Detected in some" 9 "Erythroid cells: 77.8" "Cancer enriched" "Detected in single" 10 "pancreatic cancer: 2.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 13 "NB-4: 377.2;THP-1: 184.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (2.89e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (3.99e-4)" "unprognostic (3.07e-1)" "unprognostic (1.33e-2)" "unprognostic (3.50e-2)" "unprognostic (4.04e-2)" "unprognostic (7.70e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (8.16e-2)" "unprognostic (2.56e-2)" 0.1 0.0 0.0 0.0 0.0 165.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.1 7.9 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 377.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.4 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.0 3.2 0.0 5.9 1.1 0.0 0.4 0.2 0.0 0.0 0.0 3.1 1.5 0.0 0.0 0.5 0.7 2.5 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 77.8 0.1 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.0 0.0 2.5 1.0 8.2 0.0 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 PRSS58 TRYX3 ENSG00000258223 "Serine protease 58" Q8IYP2 7 142252143-142258058 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 180 "testis: 25.8" "Group enriched" "Detected in some" 129 "Early spermatids: 640.5;Late spermatids: 243.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 640.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 243.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 403.5;Extravillous trophoblasts: 648.4;Paneth cells: 262.6;Proximal enterocytes: 358.0;Syncytiotrophoblasts: 450.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 243.7;CACO-2: 165.9;CAPAN-2: 111.9;hTCEpi: 157.8;OE19: 79.6;SK-BR-3: 186.3" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in single" HPA030436 Uncertain "Secreted - unknown location" NA NA 4400000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.8 0.4 0.3 15.0 0.4 0.2 25.5 2.1 0.6 31.1 6.7 129.4 155.7 9.9 113.0 136.2 15.4 47.7 0.4 0.6 0.2 90.6 28.0 54.1 0.3 0.3 0.2 0.6 139.4 56.0 8.4 51.0 0.4 49.0 72.6 0.0 245.4 8.5 0.3 115.3 151.8 3.5 0.1 0.2 156.2 0.5 0.2 15.4 50.8 0.0 11.8 4.9 56.0 0.2 63.4 0.2 0.1 0.2 0.0 0.0 243.7 0.0 0.0 0.0 0.0 165.9 111.9 0.0 1.3 0.0 0.0 73.5 0.1 69.7 0.0 0.3 0.4 0.1 0.3 6.5 0.0 0.0 0.3 0.0 157.8 0.0 2.4 0.0 0.0 0.1 1.9 0.1 0.0 68.1 0.6 1.4 20.5 79.6 0.1 0.5 0.0 1.2 7.5 13.1 0.9 0.7 0.0 186.3 0.1 18.8 42.8 0.8 0.0 0.1 1.9 0.6 0.4 0.3 0.5 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.1 0.6 0.6 0.2 0.3 0.2 0.4 0.1 0.2 0.2 0.4 99.3 60.1 0.0 1.0 37.9 82.7 108.9 76.2 0.5 74.4 39.2 0.3 62.9 107.4 42.3 0.0 168.8 0.8 403.5 29.4 192.4 0.0 35.2 11.4 2.6 9.6 2.7 0.1 224.4 648.4 3.5 82.6 109.5 7.0 0.0 0.0 18.2 22.8 0.0 0.2 132.1 87.5 0.3 2.7 0.0 0.6 1.9 3.6 0.0 4.2 0.3 0.0 0.0 0.0 240.7 262.6 0.0 0.1 66.0 358.0 28.6 21.2 0.1 0.0 0.1 4.7 0.0 0.2 81.9 54.0 450.7 2.2 0.0 150.8 91.0 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840999-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "bone marrow: 2098.1" "Cell type enriched" "Detected in some" 17 "Erythroid cells: 26.5" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.0" "Cell line enriched" "Detected in some" 6 "THP-1: 2054.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced Approved Vesicles,Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Vesicles "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.8 0.2 0.6 0.0 0.7 2098.1 0.4 0.2 1.3 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 1.6 0.6 0.4 0.3 2.8 11.7 0.4 0.3 0.4 0.1 0.1 0.2 1.3 0.6 0.4 0.3 0.0 0.0 1.6 0.0 0.3 1.3 0.0 0.0 0.2 38.2 0.1 0.2 0.6 7.1 0.4 0.0 0.0 0.0 0.1 0.4 1.2 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 343.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 2054.4 0.0 0.0 0.0 0.2 0.9 0.0 0.2 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 9.9 0.6 0.7 0.2 1.3 0.6 0.4 0.3 0.4 0.4 0.2 0.6 0.4 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.8 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 26.5 0.4 0.0 0.9 0.9 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 1.5 0.0 0.1 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 405.6" "Group enriched" "Detected in some" 7 "Adipocytes: 161.4;Cardiomyocytes: 161.5;Hofbauer cells: 75.1;Smooth muscle cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 166.0" "Lineage enriched" "Detected in all" 11 "dendritic cells: 166.0" "Cell line enhanced" "Detected in many" "ASC diff: 947.9;HaCaT: 276.4;HUVEC TERT2: 436.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" 405.6 25.1 112.4 15.9 110.4 3.6 210.2 97.4 119.8 92.0 122.6 51.8 84.0 52.5 212.8 83.9 30.9 30.8 76.3 121.8 104.3 110.9 197.3 20.9 18.0 108.2 111.3 30.7 66.0 69.0 59.1 45.2 108.5 70.4 43.2 42.9 50.6 44.3 49.7 81.1 59.8 19.9 103.1 12.3 24.8 51.5 131.1 34.7 55.1 75.8 26.9 71.4 51.9 101.5 26.0 62.9 105.3 0.4 947.9 0.1 7.2 4.0 22.0 2.0 0.5 60.1 76.3 16.6 82.1 0.3 47.1 276.4 9.5 10.9 0.5 1.1 17.6 32.5 23.8 89.0 91.9 0.3 9.0 71.1 20.2 6.7 0.3 250.1 436.7 95.1 26.9 0.6 0.0 89.6 41.9 4.7 51.2 39.1 0.3 117.5 48.5 0.8 223.1 106.2 107.6 76.6 11.0 147.7 168.4 78.9 66.2 46.2 119.1 0.6 1.0 0.5 0.6 9.3 22.0 0.4 66.0 0.6 7.6 1.3 3.5 11.6 6.6 0.8 5.1 15.8 3.7 5.5 3.3 11.1 13.4 13.9 2.2 6.2 0.2 166.0 0.2 4.8 112.4 110.4 97.4 119.8 121.8 104.3 108.2 111.3 108.5 103.1 131.1 101.5 161.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.5 0.0 0.0 0.0 0.0 13.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 7.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.0 PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 98.5;stomach 1: 38.6" "Cell type enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 41.8" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CACO-2: 16.6;OE19: 32.2;RPMI-8226: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" NA NA 31000 "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" 0.3 0.0 0.0 0.0 0.3 0.0 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 98.5 0.0 0.0 0.0 0.0 38.6 3.4 0.1 0.2 0.0 0.0 3.1 0.0 0.2 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 PSG1 "CD66f, PBG1, PSBG1, PSGGA" ENSG00000231924 "Pregnancy specific beta-1-glycoprotein 1" P11464 19 42866464-42879822 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 161 "placenta: 259.7" "Cell type enriched" "Detected in some" 98 "Syncytiotrophoblasts: 207.0" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "U-2197: 412.3" HPA046327 Supported "Secreted in female reproductive system" NA NA 75000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (2.02e-1)" "unprognostic (3.54e-1)" "unprognostic (2.44e-7)" "unprognostic (2.28e-2)" 0.0 0.0 0.5 0.0 0.2 0.0 0.0 1.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.0 259.7 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.6 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 18.1 6.0 1.5 2.3 0.0 0.4 0.0 0.0 21.1 4.3 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.0 21.9 0.2 0.0 0.7 0.0 0.0 412.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.6 0.9 0.5 0.0 0.2 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 207.0 0.0 0.0 0.0 0.0 PSG11 "MGC22484, PSG13, PSG14" ENSG00000243130 "Pregnancy specific beta-1-glycoprotein 11" Q9UQ72 19 43007656-43026474 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 87 "placenta: 52.9" "Cell type enriched" "Detected in some" 57 "Syncytiotrophoblasts: 161.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "U-2197: 16.4" "HPA042240, HPA046327" Enhanced "Secreted in female reproductive system" NA NA 40000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA042240: AB_10797384, HPA046327: AB_2679624" "unprognostic (2.58e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.9 0.0 0.1 0.0 0.0 PSG2 "CEA, PSBG2, PSG1, PSGGB" ENSG00000242221 "Pregnancy specific beta-1-glycoprotein 2" P11465 19 43064209-43083045 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 204 "placenta: 238.5" "Cell type enriched" "Detected in some" 30 "Syncytiotrophoblasts: 802.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 10.8;fHDF/TERT166: 23.9;HBF TERT88: 34.8;SuSa: 9.4;U-2197: 45.7" "Secreted in female reproductive system" NA NA 41000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.02e-2)" 0.0 0.0 0.3 0.0 0.2 0.8 0.0 1.1 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 238.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.9 0.3 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 1.8 1.0 4.7 0.0 0.0 0.0 0.0 23.9 1.3 0.5 0.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 45.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.1 0.7 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 2.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 802.3 0.0 0.0 0.0 0.8 PSG3 ENSG00000221826 "Pregnancy specific beta-1-glycoprotein 3" Q16557 19 42721638-42740481 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 199 "placenta: 141.5" "Cell type enriched" "Detected in some" 88 "Syncytiotrophoblasts: 1579.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2197: 1.4" HPA046327 Supported "Secreted in female reproductive system" NA NA 67000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 141.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.0 3.9 11.2 0.0 0.1 0.3 0.0 0.0 0.4 0.0 17.9 0.9 0.0 0.8 0.0 0.1 0.0 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1579.6 0.0 0.0 0.0 0.0 PSG4 ENSG00000243137 "Pregnancy specific beta-1-glycoprotein 4" Q00888 19 43192702-43207299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "parathyroid gland: 55.6;placenta: 143.4" "Cell type enriched" "Detected in some" 38 "Syncytiotrophoblasts: 553.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "fHDF/TERT166: 552.6;U-2197: 147.3" HPA046327 Supported "Secreted in female reproductive system" NA NA 58000000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (4.29e-2)" "unprognostic (5.18e-2)" "unprognostic (9.49e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (7.75e-2)" "unprognostic (8.82e-3)" "unprognostic (1.03e-3)" "unprognostic (1.68e-2)" "unprognostic (2.85e-1)" "unprognostic (2.57e-1)" 0.1 0.1 0.1 0.0 0.1 0.0 1.1 0.9 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.5 55.6 0.1 143.4 0.0 0.2 0.0 0.0 1.2 0.2 0.0 3.3 0.0 1.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.8 0.0 1.8 0.1 0.7 0.3 0.0 2.7 0.0 1.9 552.6 4.6 0.0 0.2 0.4 5.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 8.2 53.6 3.6 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.4 0.0 0.0 0.0 7.1 0.9 14.5 0.0 0.0 4.4 2.1 5.5 147.3 0.1 0.2 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.3 0.0 1.5 0.4 0.5 0.3 0.0 0.3 0.0 0.0 4.7 0.0 0.0 0.0 14.3 0.1 0.1 0.2 0.1 0.0 0.0 1.0 0.0 11.9 0.4 0.0 2.7 0.0 0.1 0.0 0.0 2.0 0.0 1.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.5 0.3 0.7 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 553.7 0.0 0.0 0.0 0.3 PSG5 "FL-NCA-3, PSG" ENSG00000204941 "Pregnancy specific beta-1-glycoprotein 5" Q15238 19 43166256-43186536 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 63 "placenta: 111.8" "Cell type enriched" "Detected in some" 44 "Syncytiotrophoblasts: 724.4" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Region enhanced" "Detected in single" "cerebellum: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 427.9;fHDF/TERT166: 1485.4" HPA046327 Supported "Secreted in female reproductive system" NA NA 22000000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (1.59e-1)" "unprognostic (3.38e-2)" "unprognostic (4.69e-2)" "unprognostic (1.62e-2)" "unprognostic (2.18e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-2)" "unprognostic (1.12e-2)" "unprognostic (2.62e-2)" "unprognostic (1.03e-1)" "unprognostic (7.92e-2)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 111.8 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.0 0.9 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.3 0.0 0.0 0.2 0.6 0.1 427.9 122.3 7.0 57.8 0.0 0.3 0.0 0.0 1485.4 1.8 16.4 0.1 0.0 65.8 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.8 0.0 1.1 7.8 2.3 0.0 0.0 0.0 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 10.2 0.0 0.0 0.1 0.5 1.6 54.9 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.7 0.4 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.3 0.0 1.2 0.0 0.1 0.1 0.0 0.5 1.8 0.0 14.2 0.0 0.1 0.0 6.0 0.8 0.0 0.0 0.2 0.0 0.0 3.3 0.0 16.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 3.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.5 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 724.4 0.0 0.1 0.0 0.1 PSG6 ENSG00000170848 "Pregnancy specific beta-1-glycoprotein 6" Q00889 19 42902086-42919563 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 49.4" "Cell type enriched" "Detected in some" 125 "Syncytiotrophoblasts: 363.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-2197: 144.6" HPA046327 Supported "Secreted in female reproductive system" NA NA 65000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (4.23e-1)" 0.0 0.0 0.4 0.1 0.2 1.4 0.0 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.9 0.5 0.6 1.1 0.0 0.3 0.0 0.0 1.9 0.1 0.2 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.9 0.0 0.0 0.0 0.1 0.3 144.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.2 1.4 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 363.5 0.0 0.0 0.0 0.0 PSG7 ENSG00000221878 "Pregnancy specific beta-1-glycoprotein 7" Q13046 19 42924132-42937207 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "placenta: 4.1;skin 1: 1.2" "Cell type enriched" "Detected in some" 95 "Syncytiotrophoblasts: 162.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.6;fHDF/TERT166: 1.1;HBF TERT88: 2.3;U-2197: 1.8" HPA046327 Supported "Secreted in female reproductive system" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 162.0 0.0 0.0 0.0 0.0 PSG8 ENSG00000124467 "Pregnancy specific beta-1-glycoprotein 8" Q9UQ74 19 42752686-42855691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "placenta: 6.5" "Cell type enriched" "Detected in some" 11 "Syncytiotrophoblasts: 34.3" "Cancer enriched" "Detected in single" 17 "thyroid cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046327 Supported "Secreted in female reproductive system" NA NA 55000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (1.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 3.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.3 0.0 0.0 0.0 0.0 PSG9 "PSG11, PSGII" ENSG00000183668 "Pregnancy specific beta-1-glycoprotein 9" Q00887 19 43211791-43269530 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 135 "placenta: 106.3" "Cell type enriched" "Detected in some" 60 "Syncytiotrophoblasts: 277.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.2;GAMG: 16.3;HBF TERT88: 9.3;SuSa: 10.7;U-2197: 9.7" HPA046327 Supported "Secreted in female reproductive system" NA NA 43000000 "Cluster 28: Placenta - Pregnancy" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" "unprognostic (9.32e-2)" "unprognostic (3.28e-1)" "unprognostic (2.15e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 106.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.7 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 5.2 2.9 4.5 2.3 0.1 0.1 0.0 0.2 1.4 16.3 0.3 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.6 10.7 4.3 0.0 0.2 0.1 2.1 9.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 4.3 1.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 277.3 0.0 0.0 0.0 0.0 PSORS1C2 "C6orf17, SPR1" ENSG00000204538 "Psoriasis susceptibility 1 candidate 2" Q9UIG4 6 31137534-31139066 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "skin 1: 188.2" "Group enriched" "Detected in some" 8 "Endometrial ciliated cells: 3.3;Glandular and luminal cells: 9.0;Melanocytes: 8.8;Suprabasal keratinocytes: 7.0" "Cancer enhanced" "Detected in many" "testis cancer: 14.6;urothelial cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061228 Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" "HPA061228: AB_2684455" "unprognostic (8.86e-2)" "unprognostic (7.73e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (5.20e-3)" "unprognostic (1.67e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (3.78e-1)" "unprognostic (1.64e-2)" "unprognostic (1.06e-1)" "unprognostic (9.40e-5)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (2.66e-1)" 1.7 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 188.2 0.4 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.3 0.0 0.2 0.2 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.8 0.4 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.5 PSPN PSP ENSG00000125650 Persephin O60542 19 6375148-6379058 "Predicted secreted proteins" "Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in many" "Early spermatids: 8.0;Late spermatids: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" CAB025366 Uncertain "Secreted in other tissues" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" "CAB025366: " "unprognostic (3.21e-1)" "unprognostic (3.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (3.67e-1)" "unprognostic (2.05e-2)" "unprognostic (5.80e-3)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (6.27e-2)" "unprognostic (1.54e-6)" "unprognostic (5.39e-3)" "unprognostic (1.01e-3)" "unprognostic (4.25e-2)" "unprognostic (2.26e-1)" "unprognostic (2.44e-1)" "unprognostic (1.60e-1)" 0.6 0.8 2.4 0.4 2.6 0.6 0.5 4.9 2.8 1.1 2.0 1.0 0.5 0.9 1.1 1.0 1.1 0.5 0.8 2.6 2.2 1.7 1.5 0.8 0.5 2.2 2.2 1.2 1.1 0.8 1.5 0.4 2.0 1.2 0.5 1.1 0.7 0.5 0.6 0.7 1.1 0.5 1.9 1.2 1.2 1.2 2.3 0.7 1.5 0.4 0.6 0.8 0.8 2.5 0.7 1.6 0.9 2.3 2.1 1.4 0.5 0.8 0.8 0.9 0.9 1.6 0.5 0.8 1.2 1.0 0.8 1.0 1.5 0.6 1.0 1.2 1.2 0.8 0.9 1.2 1.5 0.7 1.2 1.6 1.8 0.7 1.1 2.4 0.6 1.3 1.0 1.0 1.0 1.2 1.6 1.4 0.9 1.6 1.8 1.3 1.1 0.5 1.5 0.9 1.2 1.9 1.3 1.2 1.1 1.1 1.4 0.8 0.7 1.1 1.0 2.0 0.5 1.8 3.1 0.4 2.0 1.4 1.1 1.3 0.5 0.4 0.4 0.4 0.6 0.4 0.3 0.6 0.2 0.5 0.5 0.5 0.8 0.4 0.7 0.6 0.4 0.4 2.4 2.6 4.9 2.8 2.6 2.2 2.2 2.2 2.0 1.9 2.3 2.5 0.8 0.0 1.7 0.0 0.3 0.6 1.0 1.4 0.0 2.5 2.3 1.5 1.8 0.0 0.5 1.8 0.0 1.1 1.0 4.5 0.0 1.2 8.0 2.4 1.7 1.4 3.0 0.8 0.1 0.2 0.7 1.3 0.0 1.9 1.3 2.2 2.2 2.6 2.2 1.7 0.1 2.0 0.0 1.3 0.6 28.7 0.9 0.7 1.8 1.0 1.5 1.8 1.0 0.0 0.0 0.9 4.2 2.2 1.9 1.5 6.2 3.3 2.2 2.2 0.0 1.2 1.3 1.3 0.9 0.9 1.0 1.4 0.7 1.3 2.9 1.1 PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 4898.3;testis: 3242.2" "Group enriched" "Detected in many" 11 "Leydig cells: 38051.3;Peritubular cells: 65156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1386.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1386.8" "Group enriched" "Detected in some" 6 "HHSteC: 518.7;HSkMC: 252.0" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" NA NA 2500000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "CAB009916: AB_2174617, HPA004938: AB_1855745, HPA067456: " "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" 391.1 297.1 1849.2 247.1 2423.8 9.9 121.1 2440.1 2559.6 1675.5 1508.4 84.8 31.5 320.4 735.9 172.5 492.1 396.7 4898.3 1760.9 2034.8 466.5 80.2 607.8 824.1 2339.4 2228.2 66.8 113.2 9.1 398.4 227.8 2318.0 727.0 17.7 146.1 97.8 813.1 108.3 164.9 205.9 99.7 1999.6 317.5 93.0 3242.2 2264.9 127.4 55.1 60.0 306.0 230.3 1181.0 2580.3 0.1 0.0 0.1 0.0 5.4 16.7 8.8 0.3 0.0 0.0 0.0 0.0 0.2 0.6 4.0 24.0 0.0 0.8 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.3 518.7 0.3 1.3 252.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.0 0.2 0.0 0.0 6.6 0.9 8.2 0.0 0.1 0.2 1.6 0.0 0.0 1.6 2.0 0.0 0.6 0.0 0.1 0.6 68.3 0.7 0.2 0.2 2.1 0.1 0.3 0.0 0.1 3.9 0.0 0.9 0.0 0.3 0.4 50.5 1.0 3.4 0.3 4.3 6.3 1.8 0.2 0.9 9.9 2.3 3.8 0.2 1386.8 1.4 11.2 1849.2 2423.8 2440.1 2559.6 1760.9 2034.8 2339.4 2228.2 2318.0 1999.6 2264.9 2580.3 29.3 0.0 0.6 665.0 1.5 70.4 3.2 0.1 5.7 46.8 6.6 14.7 333.6 8.6 0.1 138.0 52.1 14.4 1863.6 0.2 68.4 0.3 215.9 29.7 1156.5 167.8 0.0 13.5 4.0 0.0 55.0 1584.0 1.1 20.1 1.3 0.3 46.1 1.6 57.3 21.9 12.8 0.0 0.0 3.4 161.8 1230.9 38051.3 57.0 209.9 176.1 4.6 4625.8 583.9 63.3 850.4 1.7 0.0 65156.8 6.0 20.7 0.0 1.1 0.0 130.3 164.3 787.4 124.8 130.7 111.1 12.0 80.1 35.4 61.3 0.1 0.0 14.5 PTH PTH1 ENSG00000152266 "Parathyroid hormone" P01270 11 13492054-13496181 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 245 "parathyroid gland: 50184.7" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 1.0;Oligodendrocyte precursor cells: 1.0;Oligodendrocytes: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000072, CAB023409, CAB026363, HPA048540" Enhanced "Secreted to blood" NA NA 28000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB000072: , CAB023409: AB_619175, CAB026363: , HPA048540: AB_2680435" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 50184.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.2 205.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTH2 TIP39 ENSG00000142538 "Parathyroid hormone 2" Q96A98 19 49422419-49423441 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "brain: 4.3" "Cell type enhanced" "Detected in some" "Early spermatids: 2.4;Late spermatids: 3.1;Muller glia cells: 2.4;Spermatocytes: 2.0;Spermatogonia: 2.0" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "olfactory bulb: 2.9" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (3.41e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.1 4.3 0.7 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 2.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076307-43161719 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 317.3;Endometrial stromal cells: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 13.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 13.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved "Secreted to blood" NA NA 12000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA003222: AB_1079713" "unprognostic (1.80e-1)" "unprognostic (7.49e-3)" "unprognostic (6.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (5.85e-3)" "unprognostic (9.81e-3)" "unprognostic (1.47e-3)" "unprognostic (7.15e-2)" "unprognostic (5.11e-3)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (9.12e-2)" "unprognostic (5.70e-3)" 15.0 5.0 9.6 6.7 8.4 2.8 17.5 8.5 8.9 69.5 36.0 9.4 6.5 87.4 87.1 30.1 38.2 24.7 8.8 8.7 10.8 29.3 1.6 33.9 3.9 10.2 11.4 85.3 16.4 13.0 21.1 48.8 8.7 37.9 8.5 6.0 36.7 25.4 0.6 34.6 9.5 38.7 9.0 27.8 12.2 41.7 11.2 30.4 23.0 1.5 6.4 22.3 43.6 8.2 9.1 2.5 83.6 141.6 88.0 89.9 119.4 94.2 145.5 77.0 99.4 77.0 31.0 0.2 74.0 107.3 56.4 99.5 38.0 87.5 49.3 0.7 52.0 8.5 17.1 105.2 132.5 0.3 0.4 129.1 77.4 103.2 32.6 135.8 10.1 35.0 6.2 0.2 36.4 7.0 32.5 12.6 39.1 0.8 7.0 33.3 119.0 0.3 61.0 42.4 48.3 91.6 14.8 1.5 50.0 87.8 51.9 19.5 6.8 84.1 53.1 0.4 51.0 0.5 0.9 3.2 19.1 0.3 14.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.4 0.2 0.7 0.0 13.5 0.0 0.8 9.6 8.4 8.5 8.9 8.7 10.8 10.2 11.4 8.7 9.0 11.2 8.2 3.0 16.0 13.1 10.7 0.8 17.3 19.9 40.4 27.9 4.3 23.5 32.5 1.6 5.7 14.6 12.9 56.3 19.1 6.3 1.7 1.9 21.0 317.3 23.5 84.7 8.7 21.6 4.0 8.7 6.9 2.2 30.0 8.6 25.2 1.3 25.3 2.2 0.0 3.5 0.0 5.3 3.9 42.7 0.0 9.8 48.9 18.3 4.1 16.0 1.0 1.0 20.1 0.0 3.5 1.4 10.5 4.1 18.4 1.4 11.8 0.6 0.6 15.4 2.2 13.1 8.7 27.9 2.8 21.2 13.7 10.4 8.2 3.0 17.7 6.3 11.8 PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 280.4;parathyroid gland: 383.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 672.0;Extravillous trophoblasts: 416.0;Horizontal cells: 526.6;Muller glia cells: 548.5;Oligodendrocyte precursor cells: 322.7;Squamous epithelial cells: 439.9" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "AF22: 1717.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 167000 1400000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" 26.2 18.2 212.9 4.1 206.4 0.1 82.3 217.0 280.4 100.0 182.0 31.4 5.4 76.8 55.3 78.2 19.2 55.9 87.7 209.6 205.2 38.4 8.5 18.4 7.4 220.3 200.5 19.0 8.4 383.5 126.1 36.2 196.3 116.1 21.6 63.4 37.4 52.5 2.2 9.1 10.1 54.0 204.2 40.4 15.7 53.8 207.6 21.4 18.9 18.8 11.4 24.8 65.1 209.1 1.2 0.0 1717.6 21.2 0.4 0.9 140.6 45.3 134.3 25.1 34.3 0.4 0.2 0.0 0.2 60.0 15.6 1.0 0.0 0.0 18.9 0.0 1.4 0.0 0.0 0.0 7.7 0.0 0.5 1.9 0.0 16.6 0.2 24.6 0.0 0.0 0.0 8.2 7.0 0.0 0.0 0.6 133.5 0.0 1.1 0.1 2.8 0.4 0.7 0.0 8.0 116.5 0.0 0.0 0.2 24.1 0.2 0.2 0.0 37.4 32.9 1.8 99.4 0.7 0.0 0.0 119.7 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.9 206.4 217.0 280.4 209.6 205.2 220.3 200.5 196.3 204.2 207.6 209.1 10.1 0.0 0.0 303.3 1.3 23.2 1.7 85.0 209.5 27.7 244.6 117.3 14.6 2.8 20.9 1.8 6.2 220.0 2.2 0.0 9.8 1.1 24.5 53.4 672.0 32.0 0.0 0.0 4.9 0.0 416.0 248.8 0.5 24.6 0.0 1.1 7.1 0.3 20.4 526.6 18.1 0.0 0.0 0.3 20.6 14.0 172.7 4.0 44.4 102.1 0.0 548.5 0.0 322.7 218.4 0.3 0.0 185.5 2.5 18.6 0.0 7.5 7.2 32.3 59.2 3.0 91.4 4.0 2.4 439.9 13.9 193.3 4.4 144.7 0.0 2.2 PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.8;Inhibitory neurons: 104.2;Melanocytes: 80.0;Oligodendrocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "plasmacytoid DC: 12.5" "Lineage enriched" "Detected in single" 89 "dendritic cells: 12.5" "Cell line enhanced" "Detected in many" "AN3-CA: 121.8;HaCaT: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 150000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 54.7 21.2 34.4 5.0 25.5 1.5 36.2 3.2 30.9 40.2 0.0 25.2 2.6 30.5 2.2 16.5 41.1 13.7 37.0 34.3 10.0 11.2 6.0 26.9 5.5 16.4 16.4 35.8 32.4 9.7 29.1 2.3 17.6 30.5 1.6 5.7 18.6 14.6 14.4 20.6 13.6 8.6 1.6 9.0 23.2 9.9 27.3 4.2 29.4 7.4 4.4 32.0 31.8 34.9 11.3 64.0 56.2 121.8 25.3 20.5 7.4 19.4 22.5 22.8 18.5 0.7 6.2 0.2 44.5 32.2 18.0 124.6 15.1 0.2 10.0 1.5 24.3 0.0 27.2 40.5 11.7 0.0 14.1 21.8 5.4 4.8 0.9 29.4 0.6 7.9 18.5 0.2 9.1 48.0 5.2 12.3 31.7 0.4 27.0 0.0 12.4 0.0 4.7 22.5 43.1 58.9 18.3 3.4 34.6 10.7 22.0 4.8 2.8 20.2 34.3 46.9 23.6 6.2 0.1 36.9 10.5 0.0 44.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 34.4 25.5 3.2 30.9 34.3 10.0 16.4 16.4 17.6 1.6 27.3 34.9 1.1 6.4 1.1 53.8 3.2 60.9 42.4 16.1 22.2 49.6 3.3 5.5 14.1 27.1 4.9 12.9 2.1 0.7 56.4 0.1 9.8 1.4 3.4 5.4 11.4 9.7 3.0 0.0 76.8 0.9 32.2 51.2 5.1 5.3 0.0 4.0 25.4 20.2 1.7 11.8 104.2 0.0 10.2 0.3 20.0 5.4 46.6 3.4 80.0 15.9 0.8 46.6 0.0 71.9 90.2 0.5 0.0 36.1 6.3 35.0 0.0 2.9 1.7 10.1 13.1 46.4 22.6 7.4 14.8 16.8 36.7 1.0 2.0 2.7 0.4 30.0 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;skin 1: 31.9" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 2714.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 425.5;NTERA-2: 126.3;WM-115: 193.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" NA NA 3400000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" 1.6 1.6 66.0 1.2 64.2 0.0 4.0 57.2 88.4 1.8 21.5 4.4 0.6 0.1 0.8 7.9 0.3 0.7 1.3 64.0 64.1 0.1 0.1 1.2 0.0 60.9 62.9 0.7 2.7 0.0 2.3 0.2 62.4 1.0 1.1 19.0 3.4 0.7 0.1 31.9 1.0 1.3 63.7 1.0 13.8 0.3 58.6 0.2 0.1 0.3 2.6 0.9 2.3 72.4 0.1 0.0 425.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 27.7 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 126.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 5.4 15.2 0.1 0.0 0.0 0.1 0.0 0.0 0.7 10.9 5.6 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 66.0 64.2 57.2 88.4 64.0 64.1 60.9 62.9 62.4 63.7 58.6 72.4 0.1 0.0 1.5 625.2 0.2 25.2 8.6 82.2 44.9 18.3 5.6 12.2 1.3 0.0 39.7 0.0 4.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 37.7 0.7 0.1 1.3 9.2 0.0 0.0 10.1 0.0 0.0 0.1 65.6 72.0 0.0 0.0 0.0 1.6 0.7 0.3 0.1 19.6 22.5 0.0 90.4 0.0 2714.3 3.6 0.9 0.3 0.0 1.2 1.8 0.0 0.1 16.9 6.6 0.0 1.2 1.7 0.1 1.6 14.8 21.5 0.3 0.2 0.5 0.0 7.8 PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 231.5;urinary bladder: 191.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 16.2;Fibroblasts: 44.7;Glandular and luminal cells: 24.0;Langerhans cells: 23.6;Macrophages: 27.0;Melanocytes: 14.2" "Cancer enhanced" "Detected in many" "glioma: 22.5" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.9;thalamus: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1219.3;ASC TERT1: 1751.7;BJ hTERT+: 1201.8;HHSteC: 2261.1;HSkMC: 2364.2;hTEC/SVTERT24-B: 1276.5;TIME: 1761.1;U-2197: 1605.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Approved "Plasma membrane" "Secreted to blood" NA NA 1090000 970000 "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA069320: AB_2686118" "unprognostic (1.93e-2)" "unprognostic (4.96e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (8.35e-9)" "unprognostic (5.79e-3)" "prognostic unfavorable (6.36e-4)" "unprognostic (6.03e-3)" "prognostic unfavorable (8.75e-6)" "unprognostic (2.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.60e-2)" "unprognostic (2.63e-1)" "unprognostic (2.76e-9)" "unprognostic (6.03e-3)" "unprognostic (5.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.92e-3)" 231.5 11.1 0.4 38.8 0.4 89.0 57.9 0.6 1.9 2.8 1.1 13.0 0.8 2.5 0.5 2.9 21.4 7.7 46.8 0.6 0.5 6.8 2.6 83.2 0.9 0.7 0.6 1.4 41.6 1.1 4.4 11.4 0.6 6.9 2.3 0.4 5.4 0.5 5.2 25.4 9.7 5.7 0.3 23.6 24.8 0.7 4.0 1.6 5.8 0.5 0.3 191.7 3.1 0.4 1.2 0.0 752.4 0.2 1219.3 1751.7 0.3 132.3 1201.8 56.2 60.9 0.7 7.9 0.2 460.6 157.4 87.6 0.0 0.3 1.1 110.5 0.8 0.3 2.0 0.1 0.0 2261.1 2.5 0.0 2364.2 0.8 1276.5 429.8 110.2 266.4 0.1 0.3 0.0 380.1 0.0 0.3 2.9 11.2 0.0 4.6 0.2 0.0 0.2 5.3 53.1 6.0 0.8 7.6 1.0 0.9 0.1 0.6 2.4 1761.1 252.2 12.2 1605.1 23.0 0.2 0.5 0.9 52.8 6.4 74.2 0.0 0.3 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 1.9 0.6 0.5 0.7 0.6 0.6 0.3 4.0 0.4 2.3 0.0 1.7 0.0 0.1 1.7 1.7 0.3 0.0 1.8 3.6 0.6 0.6 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 7.2 2.4 16.2 10.3 5.1 0.0 0.0 0.5 0.0 0.1 44.7 0.0 24.0 0.0 0.7 3.3 0.0 2.6 0.0 1.0 0.0 0.0 10.0 23.6 1.2 0.3 27.0 14.2 0.0 2.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.8 0.0 4.0 7.2 0.0 0.4 0.4 1.0 0.3 0.4 0.0 0.0 0.4 PTX4 C16orf38 ENSG00000251692 "Pentraxin 4" Q96A99 16 1485886-1488981 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4 "brain: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HL-60: 21.2;NB-4: 15.7" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Low region specificity" "Detected in all" HPA073694 Supported "Secreted - unknown location" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 24: NB-4 - Immune response" "HPA073694: AB_2732237" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (1.12e-1)" "unprognostic (1.84e-4)" "unprognostic (3.98e-2)" "unprognostic (5.66e-2)" "unprognostic (1.10e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-2)" "unprognostic (3.54e-1)" "unprognostic (1.52e-4)" "unprognostic (2.23e-3)" "unprognostic (4.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.03e-1)" 0.1 0.2 0.6 0.0 0.2 0.7 0.0 0.2 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.5 3.1 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 21.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 15.7 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.2 0.2 0.3 0.4 0.8 1.5 3.1 2.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 4.5;intermediate monocyte: 4.5;myeloid DC: 3.8;non-classical monocyte: 5.5" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;monocytes: 5.5" "Cell line enhanced" "Detected in many" "TIME: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" NA NA 720000000 "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" 13.9 17.5 10.2 7.1 9.1 5.1 9.6 9.0 10.0 8.7 9.3 10.3 12.5 13.9 5.2 8.4 11.8 6.2 28.5 9.0 16.6 13.6 30.7 19.4 2.7 9.7 11.0 12.5 14.0 10.3 17.3 12.5 12.4 9.7 8.8 5.4 9.9 6.4 19.0 7.1 11.1 10.5 7.4 4.6 12.3 5.8 14.9 2.5 10.6 6.2 2.8 9.1 8.5 7.9 58.8 52.1 5.6 25.0 8.6 9.7 7.4 96.7 38.8 40.7 45.8 31.9 28.2 0.1 50.6 43.7 60.2 44.4 24.3 51.1 31.7 7.8 27.1 8.8 40.3 23.3 43.7 4.1 22.2 10.6 28.0 40.9 82.5 49.7 50.7 6.6 4.3 0.5 23.4 7.8 4.2 5.8 12.5 30.1 31.7 0.1 23.2 5.0 111.8 25.5 21.2 22.9 66.3 54.3 14.7 7.2 22.8 12.5 175.3 39.0 52.8 33.7 78.2 0.3 6.3 0.2 35.3 23.4 24.6 0.2 4.5 0.0 0.1 4.5 0.0 0.0 0.0 0.2 3.8 0.0 0.2 0.1 1.1 0.7 5.5 0.5 0.0 1.7 10.2 9.1 9.0 10.0 9.0 16.6 9.7 11.0 12.4 7.4 14.9 7.9 11.1 16.0 25.2 2.3 1.6 3.6 16.0 6.9 4.0 5.7 4.7 3.4 14.4 14.3 12.2 1.8 2.1 2.9 0.2 18.5 3.9 37.9 10.5 5.4 6.3 20.4 13.1 2.1 11.4 35.3 34.8 7.7 13.7 11.6 1.3 6.5 7.9 41.1 8.4 1.7 13.7 11.3 2.0 8.9 7.5 14.3 5.6 6.8 1.8 5.6 17.2 1.8 2.1 6.0 4.6 69.6 18.0 15.8 0.2 14.4 10.8 5.7 2.8 3.4 0.0 23.8 10.4 10.4 1.5 5.8 5.5 1.0 0.9 10.8 12.7 7.4 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 PYY PYY1 ENSG00000131096 "Peptide YY" P10082 17 43952738-44004469 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "intestine: 52.5" "Cell type enriched" "Detected in some" 96 "Enteroendocrine cells: 19377.2" "Group enriched" "Detected in many" 8 "endometrial cancer: 7.9;ovarian cancer: 15.2;testis cancer: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.9" "Region enriched" "Detected in single" 14 "pons and medulla: 1.4" "Low region specificity" "Detected in single" "HPA010973, CAB016734" Enhanced "Secreted to blood" NA NA 87100 "Cluster 9: Intestine - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB016734: AB_876471, HPA010973: AB_1855194" "unprognostic (8.17e-3)" "unprognostic (5.41e-2)" "unprognostic (9.93e-2)" "unprognostic (1.81e-3)" "unprognostic (2.48e-4)" "unprognostic (5.26e-2)" "unprognostic (4.14e-2)" "unprognostic (1.80e-2)" "unprognostic (1.75e-2)" "unprognostic (1.54e-2)" "unprognostic (2.91e-1)" "unprognostic (1.29e-1)" "unprognostic (5.69e-3)" "unprognostic (3.77e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" 0.1 1.7 0.2 1.4 0.3 0.1 0.4 0.2 0.7 0.3 0.1 52.5 2.5 0.4 0.4 0.0 0.4 0.0 0.0 0.3 0.3 1.4 0.2 0.2 0.3 0.3 0.3 0.0 0.6 0.2 0.0 0.0 0.4 0.3 36.6 0.8 0.1 0.8 0.1 0.1 41.6 0.1 0.1 0.1 0.5 1.1 0.4 0.3 0.5 0.1 0.1 0.0 0.0 0.5 0.1 0.2 0.2 0.4 0.3 0.6 0.0 0.4 0.1 0.5 0.3 0.5 0.3 0.2 0.6 0.5 0.4 0.2 0.4 0.1 0.3 1.2 0.2 0.7 0.2 0.0 0.4 0.2 2.9 0.8 0.1 0.5 0.2 0.6 0.1 0.3 0.2 0.5 0.4 0.6 0.2 0.4 0.6 0.4 0.2 0.1 0.1 0.0 0.8 0.0 0.4 0.1 0.3 0.0 0.7 0.3 0.5 0.0 0.5 0.6 0.5 0.1 0.4 0.0 0.5 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.7 0.3 0.3 0.3 0.3 0.4 0.1 0.4 0.5 0.1 0.0 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 65.0 1.9 0.0 1.0 7.9 1.3 0.1 19377.2 0.0 3.5 0.0 0.1 0.0 0.0 18.9 8.9 0.1 0.0 0.0 0.0 0.0 3.3 199.9 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 35.5 0.0 0.0 0.0 20.7 0.1 0.0 0.0 0.0 0.0 0.1 2.3 4.3 0.0 0.1 0.0 1.0 0.0 36.8 0.0 PZP CPAMD6 ENSG00000126838 "PZP alpha-2-macroglobulin like" P20742 12 9148840-9208395 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 81.6" "Group enriched" "Detected in some" 4 "Early spermatids: 26.2;Hepatocytes: 26.4;Late spermatids: 11.0;Oligodendrocyte precursor cells: 8.5;Respiratory ciliated cells: 24.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0;liver cancer: 0.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 9 "HeLa: 5.7;SiHa: 2.5" "HPA041403, HPA041471" Supported "Secreted to blood" NA NA 15000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA041403: AB_10804003, HPA041471: AB_10795636" "unprognostic (8.48e-3)" "unprognostic (1.12e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-4)" "unprognostic (4.79e-1)" "unprognostic (3.50e-2)" "unprognostic (2.04e-4)" "unprognostic (4.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (9.71e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-5)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (9.81e-3)" 0.2 0.0 0.4 0.0 1.3 0.1 0.2 0.9 0.6 0.2 0.6 0.0 0.0 1.3 0.1 0.0 1.2 0.0 0.7 0.9 0.6 0.2 81.6 0.8 0.0 2.3 6.7 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 0.6 0.0 2.3 1.0 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.1 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.9 0.6 0.9 0.6 2.3 6.7 3.9 0.9 1.0 1.3 1.9 3.2 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.8 0.0 0.0 1.6 0.0 2.7 0.0 2.1 0.0 1.4 0.0 0.0 0.0 26.2 4.7 0.2 2.1 0.0 0.0 3.7 0.0 0.0 0.1 0.0 1.7 0.0 0.0 1.8 26.4 0.0 0.0 2.9 0.0 0.0 0.3 0.0 11.0 0.0 0.2 0.0 2.8 0.0 0.0 2.1 8.5 4.6 0.0 0.0 0.4 0.7 0.0 0.0 0.0 24.7 0.6 0.0 0.3 0.4 0.5 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37342827-37373322 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 170.3;epididymis: 104.0" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 217.0;Ionocytes: 138.4;Langerhans cells: 163.4;Melanocytes: 528.3" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 1527.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 1527.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 117.1;SK-MEL-30: 426.8;U-266/84: 341.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 5.6 170.3 8.4 14.2 7.5 47.3 15.8 5.1 11.5 21.2 4.2 25.3 5.6 9.8 104.0 3.4 2.2 10.8 5.1 8.9 27.4 6.1 2.6 5.6 8.1 9.7 11.6 1.0 13.7 14.8 27.0 9.2 14.7 7.2 10.2 11.9 25.5 6.7 4.1 36.3 4.5 8.3 7.8 13.9 7.6 2.0 20.3 5.1 3.8 2.8 12.5 15.2 4.6 6.7 1.0 40.7 0.1 0.0 6.0 13.3 0.1 6.6 86.5 6.4 10.1 2.9 7.1 0.2 3.0 32.6 72.9 0.1 2.7 0.6 10.3 0.6 76.0 18.7 0.3 7.7 0.6 3.0 0.1 8.5 0.0 47.3 0.2 0.4 26.2 0.0 0.0 0.0 0.2 4.5 0.0 1.7 0.6 0.3 0.0 0.0 0.0 0.8 42.6 10.9 117.1 0.2 6.4 1.4 426.8 8.0 0.7 2.9 19.4 0.0 0.2 0.1 0.6 15.3 341.7 0.3 25.8 0.3 0.0 9.8 344.8 3.2 0.4 38.7 1.0 2.6 0.6 0.5 124.7 1.2 0.5 0.3 1527.7 0.2 3.3 2.4 0.1 169.8 8.4 7.5 5.1 11.5 8.9 27.4 9.7 11.6 14.7 7.8 20.3 6.7 1.8 3.2 2.3 0.3 12.5 39.0 13.6 40.0 2.2 21.8 7.9 8.5 1.1 1.5 17.7 22.0 2.1 0.7 0.8 6.1 1.9 45.4 0.6 2.6 24.7 17.5 217.0 1.7 8.5 2.4 6.1 26.7 3.1 4.0 55.3 1.6 22.5 0.3 20.5 43.7 7.3 6.6 138.4 21.2 163.4 2.9 3.1 26.8 528.3 6.5 64.3 0.8 3.1 3.0 1.3 31.8 1.8 23.7 26.0 9.1 0.2 11.7 4.3 3.2 13.1 0.6 6.6 1.7 0.7 0.6 14.5 4.7 5.6 5.0 7.3 5.8 QRFP "26RFa, P518" ENSG00000188710 "Pyroglutamylated RFamide peptide" P83859 9 130892707-130896812 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.1;Bipolar cells: 1.0;Rod photoreceptor cells: 1.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enriched" "Detected in single" 11 "monocytes: 1.0" "Cell line enhanced" "Detected in some" "U-138 MG: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043377 Uncertain "Secreted in other tissues" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "HPA043377: AB_10959754" "unprognostic (1.79e-3)" "unprognostic (1.01e-1)" "unprognostic (2.28e-3)" "unprognostic (4.14e-3)" "unprognostic (7.78e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-3)" "unprognostic (5.11e-3)" "unprognostic (1.77e-1)" "unprognostic (2.28e-1)" "unprognostic (5.43e-3)" "unprognostic (1.02e-1)" "unprognostic (2.52e-2)" "unprognostic (2.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" "unprognostic (7.04e-3)" 0.8 0.2 0.2 0.2 0.4 0.2 0.4 0.3 0.3 0.8 0.2 2.2 0.2 0.7 0.0 1.1 0.5 0.3 0.6 0.2 0.1 0.6 0.2 0.5 0.1 0.2 0.2 0.6 1.3 0.0 1.0 0.1 0.3 1.2 0.0 0.1 0.3 0.0 0.2 0.4 0.9 0.0 0.0 0.3 1.0 1.2 0.4 0.0 0.7 0.0 0.0 1.9 0.7 0.3 0.6 0.3 0.2 1.6 0.0 0.0 0.8 0.6 0.0 0.0 0.0 1.0 0.4 0.2 0.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.5 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 2.2 0.2 1.5 1.4 0.2 0.2 1.5 0.9 0.6 0.0 0.5 0.5 0.7 0.5 0.2 0.7 0.4 0.8 0.5 0.2 3.5 0.9 1.4 1.7 0.1 0.6 0.7 0.6 0.4 1.8 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.4 0.3 0.3 0.2 0.1 0.2 0.2 0.3 0.0 0.4 0.3 0.0 3.2 1.1 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1616.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1918.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 84.8 84.9 35.8 52.1 39.4 115.5 53.2 42.7 47.3 81.7 41.1 100.1 67.5 75.2 70.2 178.4 82.3 150.3 244.9 41.5 43.4 73.8 81.7 200.0 16.3 50.0 40.7 196.1 136.3 21.0 60.2 158.9 43.2 92.3 80.9 15.2 105.6 57.5 91.2 58.6 85.7 60.0 44.0 61.9 178.3 172.9 42.6 12.1 31.9 46.0 19.6 174.1 108.7 57.7 441.4 62.0 14.8 181.0 179.1 367.8 712.5 456.5 456.6 381.6 267.1 7.3 137.7 6.8 276.7 367.8 52.6 93.7 17.6 123.5 185.0 26.4 28.0 14.1 33.6 19.4 1918.6 48.6 129.2 197.9 55.5 408.0 484.3 499.9 569.4 32.1 20.2 66.3 255.3 76.4 10.4 89.7 49.4 302.6 174.6 19.7 33.0 11.8 63.1 123.6 51.9 52.6 133.8 179.8 91.9 32.2 33.0 226.3 678.3 473.8 187.5 322.0 392.9 48.3 84.4 12.2 180.9 153.9 146.0 16.2 53.1 20.6 14.0 29.9 10.2 5.4 9.1 9.6 39.2 3.2 8.1 8.0 40.2 16.9 28.6 8.0 11.5 28.6 35.8 39.4 42.7 47.3 41.5 43.4 50.0 40.7 43.2 44.0 42.6 57.7 36.6 57.7 101.6 8.5 7.7 13.8 27.4 81.2 7.4 11.5 86.2 47.9 48.3 51.5 112.5 71.7 25.0 19.5 10.7 138.1 0.0 230.4 49.2 49.2 19.4 41.7 46.2 6.9 17.2 130.1 1616.7 78.0 136.6 80.4 25.4 27.1 89.3 4.3 68.6 6.7 17.0 185.7 132.2 45.2 35.3 20.1 177.7 48.9 44.4 8.4 49.7 53.5 10.3 24.6 23.9 249.8 165.6 71.1 12.8 35.7 9.0 9.1 47.8 6.7 32.9 13.6 31.3 30.2 32.7 10.2 9.9 154.3 13.9 13.9 89.9 68.0 R3HDML dJ881L22.3 ENSG00000101074 "R3H domain containing like" Q9H3Y0 20 44337043-44351238 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "intestine: 2.4" "Cell type enriched" "Detected in single" 5 "Microglial cells: 1.0" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.0;OE19: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA070264 Enhanced "Secreted - unknown location" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "HPA070264: AB_2686244" "unprognostic (1.89e-1)" "unprognostic (2.23e-1)" "unprognostic (9.86e-2)" "unprognostic (9.12e-2)" "unprognostic (6.06e-3)" "unprognostic (2.64e-1)" "unprognostic (6.32e-2)" "unprognostic (4.95e-3)" 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.7 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 42.9;Club cells: 14.8;Ionocytes: 12.2;Respiratory ciliated cells: 23.3;Squamous epithelial cells: 8.9;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.5;hTCEpi: 22.6;SiHa: 11.9;U-87 MG: 9.3" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" 2.8 8.4 0.4 0.4 0.3 0.0 0.6 0.0 0.4 4.1 0.0 0.2 0.1 0.3 0.7 15.1 0.6 0.7 0.6 0.4 0.3 0.9 0.1 0.5 0.1 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.1 0.7 0.1 0.1 3.7 1.0 0.2 2.7 0.2 0.6 0.0 0.1 0.4 0.3 0.7 0.0 0.4 0.1 1.1 1.8 6.0 0.0 1.0 1.4 0.0 1.7 2.3 1.7 0.0 0.8 3.0 1.3 1.9 0.0 1.5 0.0 0.6 1.7 1.4 2.7 0.9 5.3 1.1 0.3 1.6 0.5 29.5 0.0 0.7 0.0 0.0 3.3 22.6 3.5 1.7 1.5 0.3 0.7 0.3 0.2 0.6 1.3 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 1.0 3.2 0.3 0.3 11.9 0.5 0.0 0.1 0.4 0.4 1.6 0.6 0.5 1.6 0.8 0.0 0.0 0.0 9.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.4 0.4 0.3 0.3 0.6 0.1 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 3.1 5.1 42.9 2.8 0.0 0.4 0.4 0.1 1.5 14.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.4 0.1 1.3 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.7 0.1 0.9 0.0 3.6 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 23.3 0.0 0.0 0.2 1.1 0.0 0.3 8.9 1.7 0.1 0.3 0.5 0.0 8.1 RARRES2 "HP10433, TIG2" ENSG00000106538 "Retinoic acid receptor responder 2" Q99969 7 150338317-150341662 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 2400.4;liver: 1994.6;pancreas: 1482.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 659.2;Hepatocytes: 2819.0;Muller glia cells: 785.1" "Cancer enhanced" "Detected in all" "liver cancer: 420.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 5.4" "Group enriched" "Detected in many" 6 "AF22: 132.9;Hep G2: 213.8;HHSteC: 172.9;NTERA-2: 411.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 75000000 460000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (2.72e-2)" "unprognostic (2.82e-3)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (2.50e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.83e-4)" "unprognostic (2.94e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.17e-2)" 525.6 2400.4 61.0 87.4 62.1 0.4 295.6 56.2 70.2 522.4 321.7 386.8 53.2 359.2 55.9 78.7 408.5 116.5 212.7 62.0 63.3 271.9 1994.6 466.8 109.8 65.9 73.6 626.3 1482.0 627.1 104.1 59.0 63.3 262.5 78.3 33.9 56.2 114.7 18.3 60.4 185.9 103.0 64.8 149.5 180.0 26.9 64.5 9.8 85.0 34.6 63.1 265.3 380.7 66.7 0.0 0.1 132.9 0.3 0.0 0.0 2.1 11.9 25.2 4.2 17.2 1.2 8.2 1.1 15.0 2.9 1.3 0.5 0.0 0.0 0.0 2.4 0.5 0.6 23.6 213.8 172.9 2.2 0.4 36.4 0.0 0.0 0.0 2.8 0.0 0.4 0.4 0.4 4.2 0.9 2.1 2.4 411.9 1.2 0.0 0.1 17.1 0.4 2.8 1.1 0.6 1.2 2.3 0.1 0.4 1.9 0.6 0.0 0.0 0.4 1.8 0.8 0.6 1.4 0.9 1.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 5.4 0.0 0.0 61.0 62.1 56.2 70.2 62.0 63.3 65.9 73.6 63.3 64.8 64.5 66.7 47.1 67.3 32.0 9.4 7.0 35.1 80.7 16.8 15.9 7.0 26.2 39.0 75.0 381.8 45.0 82.8 2.1 10.1 1.9 172.6 103.7 19.8 3.7 39.9 128.7 27.1 97.4 32.0 0.4 659.2 4.3 469.6 8.2 16.4 12.0 207.5 84.6 2819.0 11.6 10.1 0.4 233.9 541.2 53.8 42.4 19.3 454.2 8.9 44.4 7.5 1.0 785.1 0.0 9.0 0.3 209.1 107.4 194.9 1.2 82.0 1.2 269.1 29.8 25.4 13.1 302.5 181.1 4.9 5.2 4.4 28.8 14.6 12.3 307.5 418.7 31.9 RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348363-47357881 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transport "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 335 "retina: 542.3" "Group enriched" "Detected in some" 11 "Cone photoreceptor cells: 2070.4;Rod photoreceptor cells: 1610.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA041301: AB_2677398, HPA044239: AB_2678868" "unprognostic (3.48e-2)" "unprognostic (4.78e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.58e-2)" "unprognostic (5.09e-2)" "unprognostic (5.14e-3)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.1 0.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 542.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.3 1.2 1.6 0.5 0.3 0.6 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.7 0.0 0.0 0.5 0.0 0.0 0.0 2070.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 43.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1610.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 REG1A "PSP, PSPS, PSPS1, PTP, REG" ENSG00000115386 "Regenerating family member 1 alpha" P05451 2 79120362-79123409 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 103906.5" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 115721.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 1268.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 12.3;EFO-21: 18.3;HDLM-2: 15.2;NB-4: 11.0;OE19: 10.7;RPMI-8226: 32.5;SH-SY5Y: 12.5;U-2 OS: 31.1;U-251 MG: 10.8;U-266/84: 13.3" "CAB025138, HPA045549, HPA045579" Enhanced "Secreted to digestive system" NA NA 68000000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB025138: , HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (1.89e-1)" "unprognostic (2.91e-2)" "unprognostic (3.39e-1)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.52e-2)" "unprognostic (3.54e-3)" "unprognostic (5.53e-2)" "unprognostic (5.54e-2)" 26.8 5.8 0.0 198.7 0.0 20.7 9.9 0.0 0.0 10.9 0.0 96.5 7597.3 5.3 0.0 9.3 6.4 96.6 10.2 0.0 0.0 93.0 15.9 4.5 7.5 0.0 0.0 25.6 103906.5 0.0 8.5 3.4 0.0 6.1 283.0 0.0 9.4 0.1 4.3 28.1 5638.4 178.1 0.0 8.5 945.9 3.9 0.0 0.0 4.0 0.0 0.4 3.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.5 10.7 0.0 0.0 0.0 32.5 0.0 0.0 1.4 12.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 31.1 2.0 10.8 0.0 13.3 5.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.0 0.0 25.5 1.9 1549.8 0.1 0.1 0.0 12.7 5.3 0.0 0.0 115721.8 0.0 0.9 692.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1813.1 0.0 0.0 0.0 0.1 0.0 17.0 0.0 0.0 507.5 0.0 0.0 0.0 0.0 22774.8 732.4 0.0 0.2 0.0 5100.1 20.8 0.0 0.0 0.0 0.0 51.7 0.0 0.4 0.0 0.0 0.0 0.6 0.0 5419.7 0.0 REG1B "PSPS2, REGH, REGI-BETA, REGL" ENSG00000172023 "Regenerating family member 1 beta" P48304 2 79085023-79088019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 39745.3" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 36125.0" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 201.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 4.1;RPMI-8226: 3.0;U-2 OS: 15.7;U-251 MG: 3.9;U-266/84: 3.8" "HPA045549, HPA045579" Supported "Secreted to digestive system" NA NA 32000000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (4.08e-1)" "unprognostic (1.09e-1)" "unprognostic (3.51e-3)" "unprognostic (9.20e-2)" 14.6 2.1 0.0 35.8 0.0 9.8 3.3 0.0 0.1 3.9 0.0 17.3 738.0 2.0 0.0 3.5 2.1 0.4 3.3 0.0 0.0 2.6 5.5 1.7 1.7 0.0 0.0 2.1 39745.3 0.0 3.1 0.1 0.0 2.0 108.1 0.0 3.1 0.0 1.6 16.1 2754.3 112.1 0.0 3.2 5.0 1.5 0.0 0.0 1.7 0.0 0.0 1.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.1 3.9 0.0 3.8 1.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 86.7 0.0 0.0 0.0 3.3 1.8 0.0 0.0 36125.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.6 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 178.3 0.0 0.0 0.0 0.0 7978.5 174.7 0.0 0.0 0.0 3101.3 0.1 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 178.8 0.0 REG3A "HIP, PAP, PAP1, PBCGF, REG-III, REG3" ENSG00000172016 "Regenerating family member 3 alpha" Q06141 2 79157003-79159753 "Plasma proteins, Predicted secreted proteins, Transporters" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 61 "intestine: 6743.6;pancreas: 12212.2" "Group enriched" "Detected in some" 11 "Exocrine glandular cells: 1988.6;Pancreatic endocrine cells: 5382.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 710.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 17.6;EFO-21: 15.8;HDLM-2: 15.4;NB-4: 17.7;RPMI-8226: 24.6;SH-SY5Y: 14.6;U-2 OS: 28.5;U-251 MG: 11.0;U-266/84: 15.1" "HPA047894, HPA048334, HPA060705" Supported Approved Cytosol "Secreted to digestive system" NA NA 23000000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (2.43e-2)" "unprognostic (2.12e-1)" "unprognostic (3.62e-2)" "unprognostic (1.42e-1)" 18.5 10.0 0.0 13.3 0.0 0.2 0.6 0.0 0.0 0.3 0.0 19.2 5180.0 2.9 0.0 1.4 0.2 24.9 1.0 0.0 0.0 2.6 2.0 0.5 4.9 0.0 0.0 0.9 12212.2 0.0 2.1 0.1 0.0 0.5 0.0 0.0 2.1 0.0 0.6 0.4 6743.6 0.2 0.0 1.3 156.5 0.9 0.0 0.0 0.6 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.1 0.4 0.0 0.0 0.0 24.6 0.0 0.0 1.8 14.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.5 5.4 11.0 0.0 15.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 152.8 7.7 0.0 0.0 3.0 0.0 0.0 0.0 1988.6 0.0 0.0 189.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.2 0.0 0.0 0.0 6.8 0.0 1.4 0.0 0.0 55.8 0.0 0.0 0.0 0.0 5382.1 32.5 0.0 0.2 0.0 215.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 315.9 0.0 REG3G "LPPM429, PAP1B, UNQ429" ENSG00000143954 "Regenerating family member 3 gamma" Q6UW15 2 79025686-79028505 "Predicted secreted proteins" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "pancreas: 3517.1" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 184.9;Pancreatic endocrine cells: 53.5;Proximal enterocytes: 39.4" "Cancer enriched" "Detected in many" 13 "pancreatic cancer: 71.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047894, HPA048334, HPA060705" Uncertain Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (8.82e-2)" "unprognostic (7.20e-3)" "unprognostic (5.64e-2)" 1.0 46.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 2.4 0.1 165.7 0.3 0.3 0.0 0.2 0.0 0.0 6.0 0.4 0.1 0.0 0.0 0.0 0.2 3517.1 0.0 0.3 1.1 0.0 0.1 0.0 0.0 0.3 1.3 0.2 0.1 37.0 1.5 0.0 0.2 0.4 57.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.7 0.0 0.0 0.1 0.0 0.0 0.0 184.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 6.2 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 53.5 0.0 0.7 0.0 0.4 39.4 2.2 0.0 0.0 0.0 0.0 0.2 1.3 1.2 0.0 0.0 0.0 0.0 0.9 5.4 0.0 REG4 "GISP, REG-IV, RELP" ENSG00000134193 "Regenerating family member 4" Q9BYZ8 1 119794017-119811580 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 662.5" "Cell type enriched" "Detected in some" 7 "Intestinal goblet cells: 3458.1" "Group enriched" "Detected in many" 21 "colorectal cancer: 180.6;pancreatic cancer: 215.1;stomach cancer: 162.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive CD8 T-cell: 24.6" "Lineage enriched" "Detected in single" 101 "T-cells: 24.6" "Cell line enriched" "Detected in some" 60 "OE19: 6164.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025867, HPA046555" Enhanced "Secreted to digestive system" NA NA 460000 "Cluster 32: T-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB025867: , HPA046555: AB_2679696" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (2.86e-3)" "unprognostic (2.57e-1)" "unprognostic (6.52e-2)" "unprognostic (6.20e-3)" "unprognostic (1.11e-1)" "unprognostic (1.64e-2)" "unprognostic (7.10e-2)" "unprognostic (7.85e-2)" "unprognostic (2.99e-1)" "unprognostic (5.12e-3)" "unprognostic (8.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-3)" 0.7 0.0 0.0 34.4 0.1 0.3 0.0 0.1 0.2 0.4 0.1 236.2 264.5 0.5 0.0 1.5 0.0 0.5 0.0 0.1 0.1 0.7 0.3 0.0 1.6 0.1 0.1 0.0 133.7 0.0 0.0 0.0 0.2 2.6 314.0 0.0 2.3 0.2 0.0 0.0 662.5 8.5 0.0 0.2 19.0 2.4 0.1 0.4 0.0 0.0 0.8 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.3 2.3 0.1 6164.0 102.7 0.0 0.0 0.8 0.0 29.2 0.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 3.8 24.6 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 10.8 0.0 0.0 0.0 441.8 0.0 0.0 1.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3458.1 0.0 0.0 0.0 25.9 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 140.0 0.0 0.1 3.8 178.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 2.9 0.1 52.0 0.2 RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 64.4" "Group enriched" "Detected in some" 8 "Hepatic stellate cells: 128.5;Inhibitory neurons: 372.4" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Region enriched" "Detected in many" 10 "cerebellum: 64.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 16.2;PC-3: 8.6;SCLC-21H: 11.1;SH-SY5Y: 13.7;TIME: 33.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 110.0" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" NA NA 30000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.42e-1)" "unprognostic (2.93e-3)" "unprognostic (4.31e-2)" "unprognostic (1.29e-4)" "unprognostic (1.30e-1)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (8.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-3)" "unprognostic (3.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" 1.3 1.8 2.0 0.6 1.8 0.0 2.7 64.4 3.8 1.5 0.6 0.8 0.2 0.4 0.1 0.8 2.8 0.7 1.7 3.3 6.4 0.4 13.4 0.5 0.4 2.6 4.2 0.4 0.1 0.0 0.5 0.0 6.3 0.6 0.9 2.9 0.8 0.9 0.2 0.6 0.9 0.7 3.9 0.3 0.5 0.7 0.5 0.0 1.7 1.1 0.2 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 4.3 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.0 11.1 13.7 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.8 64.4 3.8 3.3 6.4 2.6 4.2 6.3 3.9 0.5 0.5 1.0 0.0 0.0 9.1 0.5 0.6 0.0 0.0 0.6 30.2 0.5 0.4 5.1 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 13.6 0.1 0.0 8.3 0.0 7.0 2.6 1.2 0.1 7.5 0.0 0.1 0.0 0.0 128.5 3.3 0.2 0.0 372.4 0.0 0.0 5.3 2.2 6.1 0.0 0.1 0.0 2.8 0.0 0.2 0.0 3.0 10.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.8 0.7 0.1 0.8 0.0 0.6 0.3 0.4 0.0 0.0 0.0 REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 162.2" "Cell type enhanced" "Detected in some" "Early spermatids: 6.8;Late spermatids: 28.4;Paneth cells: 5.6;Smooth muscle cells: 10.7;Urothelial cells: 7.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.0;BJ: 2.0;HMC-1: 2.6;SK-BR-3: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA005131 Approved "Secreted to blood" NA NA 692000 10000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" 1.0 1.4 0.3 0.2 0.9 0.0 0.1 0.0 0.2 4.3 3.2 0.4 0.3 9.6 0.3 0.2 2.3 0.1 1.8 0.2 0.0 162.2 0.7 0.7 0.0 0.3 0.4 16.3 0.0 0.0 0.6 15.2 0.1 0.3 0.2 0.1 0.8 0.8 0.0 0.1 0.1 1.5 0.0 0.1 0.0 0.9 0.2 0.5 0.0 0.0 0.5 5.2 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.2 0.2 0.0 0.3 0.4 0.1 0.0 0.2 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.8 0.7 0.0 0.7 0.1 0.0 0.2 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 1.2 6.8 0.2 0.5 0.4 0.0 0.0 0.3 1.1 0.2 2.8 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 28.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 5.6 0.4 0.0 1.8 0.0 0.0 0.0 0.3 0.0 0.0 10.7 0.3 0.2 0.0 0.0 1.1 0.1 1.3 0.0 7.0 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 RETNLB "FIZZ2, HXCP2, RELMb" ENSG00000163515 "Resistin like beta" Q9BQ08 3 108743424-108757384 "Predicted secreted proteins, Transporters" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "intestine: 245.5" "Cell type enriched" "Detected in some" 38 "Intestinal goblet cells: 210.1" "Cancer enriched" "Detected in some" 10 "colorectal cancer: 16.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "OE19: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA049152 Enhanced "Secreted to blood" NA NA 123000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA049152: AB_2680655" "prognostic favorable (6.86e-5)" "unprognostic (1.19e-3)" "unprognostic (3.37e-2)" "unprognostic (4.69e-2)" "unprognostic (2.67e-2)" "unprognostic (5.78e-2)" "unprognostic (4.26e-1)" 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 75.7 16.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 245.5 0.0 0.0 0.1 0.0 0.0 34.5 0.8 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 2.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 210.1 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 5.5 0.0 RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035273-93089204 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3;skeletal muscle: 199.1" "Cell type enhanced" "Detected in many" "Astrocytes: 143.3;Leydig cells: 119.0;Peritubular cells: 116.9;Prostatic glandular cells: 61.3;Skeletal myocytes: 69.3;Squamous epithelial cells: 58.3" "Cancer enriched" "Detected in many" 6 "glioma: 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 50.0;BEWO: 14.6;MOLT-4: 15.5;NTERA-2: 22.2;REH: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 2000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012343: AB_777667, HPA039880: AB_2676723, HPA044222: AB_2678861" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (8.85e-2)" "unprognostic (3.96e-3)" "unprognostic (5.73e-2)" "unprognostic (4.72e-3)" "unprognostic (2.53e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (3.59e-4)" "unprognostic (8.11e-2)" "unprognostic (2.92e-2)" "unprognostic (1.73e-1)" "unprognostic (7.98e-5)" 30.2 3.2 62.1 22.5 73.8 0.4 30.3 72.5 59.1 55.9 7.7 79.4 9.9 50.9 2.9 57.4 39.9 7.7 29.4 60.4 68.0 3.6 0.6 4.6 2.4 126.3 113.9 38.5 11.4 0.8 6.9 1.3 70.4 12.8 6.2 1.0 24.2 6.4 199.1 17.1 42.9 60.6 91.5 1.3 73.6 33.5 120.6 2.6 10.0 45.0 3.4 10.0 29.2 62.8 2.1 0.3 50.0 0.8 10.3 5.7 14.6 0.3 0.0 0.0 0.0 0.6 0.6 0.1 0.2 0.4 0.0 3.4 8.4 0.2 0.0 0.0 9.2 0.1 0.3 0.0 0.0 0.1 0.2 6.1 0.2 0.0 0.0 0.3 0.0 0.9 0.0 0.1 0.0 1.0 15.5 0.2 22.2 0.1 0.0 13.1 11.4 0.1 0.0 0.5 5.1 3.0 0.5 0.2 0.0 2.6 4.0 2.7 0.0 0.1 10.4 0.3 0.1 0.1 0.0 0.2 0.2 0.2 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 62.1 73.8 72.5 59.1 60.4 68.0 126.3 113.9 70.4 91.5 120.6 62.8 4.2 0.0 1.5 143.3 0.5 5.5 20.4 10.2 40.5 1.9 7.5 4.4 4.4 0.0 3.9 0.0 2.1 4.4 0.5 0.3 0.0 6.5 1.2 0.6 10.9 2.7 0.0 0.4 16.8 0.7 1.2 40.5 1.5 2.3 0.0 0.6 1.8 0.3 2.1 0.0 2.8 0.0 12.2 2.5 2.3 6.4 119.0 1.6 3.6 9.4 0.6 4.5 0.0 11.1 1.6 0.4 0.0 116.9 0.1 61.3 0.0 0.1 1.3 1.2 13.1 69.3 20.3 0.9 43.8 58.3 2.8 2.5 1.4 0.1 0.1 29.2 RLN1 H1 ENSG00000107018 "Relaxin 1" P04808 9 5334930-5339876 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "prostate: 23.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.8;Enteroendocrine cells: 4.8;Prostatic glandular cells: 10.6;Spermatocytes: 2.4;Spermatogonia: 3.1" "Cancer enriched" "Detected in some" 106 "prostate cancer: 67.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEL: 1.2" "Secreted to blood" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 35: Glandular cells - Unknown function" "unprognostic (7.12e-6)" "unprognostic (2.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.98e-1)" "unprognostic (2.22e-2)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (4.08e-4)" "unprognostic (8.15e-2)" "unprognostic (2.89e-4)" "unprognostic (8.82e-3)" "unprognostic (3.23e-2)" "unprognostic (3.23e-2)" "unprognostic (1.53e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.9 0.2 0.0 0.5 1.0 0.8 0.2 2.8 0.1 0.0 0.0 0.7 0.3 0.0 0.0 0.6 1.6 0.7 0.2 0.1 4.8 1.7 0.0 0.5 0.4 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.4 10.6 0.0 0.4 1.0 0.8 0.0 0.2 0.1 2.4 3.1 0.0 0.1 1.1 1.6 0.1 0.2 0.3 RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299864-5304716 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.2" "Cell type enhanced" "Detected in many" "Early spermatids: 13.0;Muller glia cells: 9.6;Spermatocytes: 17.3;Syncytiotrophoblasts: 13.5" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;prostate cancer: 6.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 26 "gdT-cell: 1.4;MAIT T-cell: 4.2;memory B-cell: 1.9;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 3.0;NK-cell: 3.5;T-reg: 1.3" "Group enriched" "Detected in many" 33 "B-cells: 1.9;NK-cells: 3.5;T-cells: 4.2" "Cell line enhanced" "Detected in some" "Daudi: 5.6;HEL: 21.9;T-47d: 6.1;U-266/84: 10.2" "Secreted to blood" NA NA 24400 10000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-3)" "unprognostic (1.26e-1)" "unprognostic (2.09e-3)" "unprognostic (2.84e-1)" "unprognostic (2.03e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (2.50e-3)" "unprognostic (9.18e-2)" "unprognostic (1.74e-6)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-4)" 0.4 0.0 0.4 1.4 0.5 0.3 2.3 0.6 0.7 0.4 0.5 0.5 0.0 0.5 0.3 0.3 5.2 0.2 0.5 0.4 0.5 1.9 0.0 0.7 2.8 0.6 0.5 0.1 0.5 4.2 2.9 0.6 0.6 3.9 0.4 2.9 0.3 0.6 0.0 0.4 0.5 0.2 0.5 0.9 0.5 2.8 0.5 2.7 0.8 0.2 2.3 0.2 0.1 0.5 3.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.0 0.3 1.6 5.6 0.4 0.0 0.0 0.9 0.0 2.8 0.7 4.4 2.0 21.9 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.5 0.0 0.0 0.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.6 2.7 3.0 0.0 0.6 0.1 0.2 6.1 0.1 0.2 0.0 0.5 0.0 0.1 1.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.2 1.9 2.8 2.3 0.0 1.4 4.0 3.0 0.0 3.5 0.0 0.0 1.3 0.8 0.4 0.5 0.6 0.7 0.4 0.5 0.6 0.5 0.6 0.5 0.5 0.5 0.8 3.2 0.6 0.3 2.6 0.5 2.3 1.5 1.2 1.5 3.8 3.0 1.9 1.5 1.2 1.8 0.0 6.3 1.3 0.1 7.9 2.8 13.0 3.3 0.3 0.8 3.6 1.7 0.4 1.5 2.3 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.6 3.3 0.9 1.7 2.0 0.0 0.0 5.3 0.6 0.1 0.0 1.0 0.8 9.6 4.1 0.0 0.9 0.8 0.2 0.4 0.5 1.0 0.1 1.4 5.0 1.7 0.0 0.6 0.4 17.3 5.1 1.4 1.3 13.5 3.4 0.0 1.5 0.5 RLN3 "H3, RXN3, ZINS4" ENSG00000171136 "Relaxin 3" Q8WXF3 19 14028148-14031551 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "parathyroid gland: 1.6;testis: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "midbrain: 11.7;pons and medulla: 27.2" "Region enriched" "Detected in many" 9 "pons: 23.6" "Secreted to blood" NA NA 60000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (1.96e-2)" "unprognostic (2.54e-2)" "unprognostic (3.94e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RNASE10 "RAH1, RNASE9" ENSG00000182545 "Ribonuclease A family member 10 (inactive)" Q5GAN6 14 20505537-20511169 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Fertilization" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "head and neck cancer: 2.0;testis cancer: 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 7.2;U-2 OS: 10.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052593 Uncertain "Secreted - unknown location" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA052593: AB_2681878" "unprognostic (2.48e-3)" "unprognostic (2.22e-1)" "unprognostic (2.46e-2)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (5.91e-3)" "unprognostic (5.03e-3)" "unprognostic (5.58e-3)" "unprognostic (4.20e-2)" "unprognostic (3.04e-1)" "unprognostic (1.98e-3)" "unprognostic (1.11e-1)" "unprognostic (7.88e-4)" "unprognostic (1.58e-1)" "unprognostic (3.62e-1)" "unprognostic (8.76e-2)" "unprognostic (2.58e-1)" 2.1 1.8 3.2 1.6 3.0 1.1 0.4 2.8 4.3 0.5 2.8 0.7 1.6 2.0 1.1 1.1 1.1 0.6 0.4 3.2 2.4 0.9 0.8 1.6 0.8 3.8 3.0 1.1 0.4 0.4 0.5 0.8 3.2 1.2 0.4 0.5 0.9 0.7 2.0 2.5 1.7 0.5 1.8 1.3 1.1 1.9 3.1 0.5 0.7 0.2 0.4 0.7 0.5 5.2 4.4 2.0 0.9 1.9 0.2 0.4 2.8 0.2 0.4 0.1 0.3 0.9 1.2 0.5 1.3 0.5 0.6 2.3 0.0 0.3 0.1 1.7 0.7 0.0 1.5 0.6 0.5 0.1 2.0 0.7 1.5 0.1 2.3 0.4 1.0 0.7 1.0 2.3 0.0 1.2 0.7 1.1 0.5 0.6 0.2 3.3 0.3 2.6 0.7 1.8 1.1 1.4 7.2 1.7 0.9 0.9 1.6 0.7 0.4 0.7 10.8 0.9 0.8 2.2 0.9 0.2 0.8 0.6 0.9 1.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.3 0.0 0.0 3.2 3.0 2.8 4.3 3.2 2.4 3.8 3.0 3.2 1.8 3.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 RNASE11 "C14orf6, RAJ1" ENSG00000173464 "Ribonuclease A family member 11 (inactive)" Q8TAA1 14 20583559-20609884 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 444.4" "Group enriched" "Detected in some" 63 "Early spermatids: 32.1;Late spermatids: 57.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA003724 Uncertain "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA003724: AB_1079817" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 444.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 61.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE12 RAI1 ENSG00000258436 "Ribonuclease A family member 12 (inactive)" Q5GAN4 14 20590193-20590823 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 300 "epididymis: 862.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044175, HPA059465" Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA044175: AB_10960390, HPA059465: AB_2732638" 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 862.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE13 RAL1 ENSG00000206150 "Ribonuclease A family member 13 (inactive)" Q5GAN3 14 21032818-21034807 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 306.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (2.54e-1)" "unprognostic (2.52e-1)" "unprognostic (2.86e-1)" "unprognostic (8.40e-2)" "unprognostic (1.93e-1)" "unprognostic (7.15e-2)" "unprognostic (1.63e-3)" "unprognostic (5.20e-4)" "unprognostic (1.47e-2)" 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 306.9 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.9 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RNASE3 "ECP, RAF1, RNS3" ENSG00000169397 "Ribonuclease A family member 3" P12724 14 20891399-20892348 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 95 "bone marrow: 934.3" "Cell type enhanced" "Detected in some" "Early spermatids: 22.9;Erythroid cells: 5.9;Kupffer cells: 4.5;Late spermatids: 10.9;Macrophages: 3.0;Rod photoreceptor cells: 3.5" "Cancer enriched" "Detected in single" 8 "glioma: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 22 "eosinophil: 304.6" "Lineage enriched" "Detected in many" 22 "granulocytes: 304.6" "Cell line enhanced" "Detected in some" "HL-60: 150.4;NB-4: 51.1;THP-1: 63.6;U-937: 301.8" HPA056183 Enhanced "Secreted to blood" NA NA 4200000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA056183: AB_2683059" "unprognostic (2.54e-2)" "unprognostic (6.61e-2)" "unprognostic (1.84e-1)" "unprognostic (2.50e-1)" "unprognostic (1.37e-2)" "unprognostic (8.21e-2)" "unprognostic (6.45e-2)" "unprognostic (9.20e-3)" "unprognostic (1.20e-1)" "unprognostic (9.21e-2)" "unprognostic (8.62e-7)" "unprognostic (6.29e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (2.37e-1)" 0.4 0.4 0.5 0.5 0.5 934.3 0.1 0.5 1.2 0.1 0.3 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.2 0.5 1.0 0.2 2.0 2.7 0.7 1.1 0.7 0.2 0.1 0.0 0.3 0.6 0.9 0.2 0.1 3.8 1.2 0.1 0.1 1.7 0.1 1.0 1.0 9.8 0.1 1.8 0.5 9.4 0.1 0.0 0.0 0.3 0.1 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 150.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 63.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 301.8 0.0 11.3 8.8 304.6 0.0 1.2 0.1 0.0 0.0 0.0 14.1 0.0 0.0 0.0 4.3 0.0 0.5 1.6 0.0 4.4 0.5 0.5 0.5 1.2 0.5 1.0 1.1 0.7 0.9 1.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.1 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.5 0.0 10.9 0.3 3.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 478.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 67.3;Gastric mucus-secreting cells: 47.4;Hepatocytes: 55.8;Intestinal goblet cells: 110.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 92.6;ASC TERT1: 107.2;Hep G2: 136.9;HSkMC: 63.1;OE19: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 61000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" 106.4 7.8 5.5 8.9 5.7 1.2 96.6 5.4 8.3 95.6 8.5 56.5 22.0 59.2 37.0 20.1 77.3 55.6 44.1 5.5 8.1 40.3 478.8 40.3 12.2 6.9 6.6 111.7 41.0 14.7 12.5 5.7 6.9 76.7 65.2 4.7 74.8 45.8 14.1 47.4 41.9 25.9 6.7 11.8 84.7 10.6 5.3 5.8 26.5 31.5 10.6 65.3 75.9 7.8 2.7 12.1 2.6 0.1 92.6 107.2 0.5 10.5 23.8 1.4 4.5 3.4 4.1 0.1 2.9 24.6 6.2 2.5 1.4 2.6 1.7 17.2 1.8 0.3 2.9 136.9 10.2 1.3 0.6 63.1 5.8 1.6 10.3 34.6 12.6 4.2 0.1 12.2 6.9 1.5 1.0 0.2 0.5 92.3 10.3 0.6 2.1 3.6 2.9 2.4 0.1 0.5 5.0 2.3 2.6 4.2 3.4 0.2 13.3 3.0 1.7 4.1 0.3 2.6 3.5 0.4 4.7 1.3 2.7 0.2 24.1 0.1 0.8 1.2 1.0 5.3 1.5 0.6 13.8 4.9 0.3 0.6 0.6 0.6 0.1 3.3 3.3 8.4 5.5 5.7 5.4 8.3 5.5 8.1 6.9 6.6 6.9 6.7 5.3 7.8 1.8 38.5 19.1 2.0 3.4 2.8 1.7 2.5 11.4 0.0 9.9 2.5 0.2 28.6 4.7 3.7 0.0 0.2 0.3 30.4 0.0 34.4 0.2 0.1 0.8 4.0 67.3 8.4 0.1 22.2 0.4 39.2 47.4 0.8 1.3 0.3 5.0 55.8 1.6 0.0 0.2 110.0 2.0 6.2 4.0 0.3 12.5 3.6 3.6 1.9 2.7 1.3 1.0 0.0 0.9 12.8 33.2 4.1 5.9 1.7 41.7 10.2 11.6 0.3 0.0 2.6 8.1 0.2 0.1 10.2 4.1 0.4 0.8 0.1 39.6 1.5 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 74.9;lymphoid tissue: 24.1;skin 1: 27.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.2;Cholangiocytes: 8.6;Prostatic glandular cells: 7.3;Urothelial cells: 27.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 24.7;hTCEpi: 10.3;hTERT-HME1: 53.3" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" NA NA 280000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" 0.1 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 74.9 0.0 6.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.5 0.0 4.7 0.5 0.3 27.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.0 0.0 0.0 24.1 0.2 9.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 53.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 30.2 1.5 0.0 0.0 0.1 2.4 0.5 8.6 0.4 0.0 0.0 1.5 0.0 0.1 0.0 4.5 0.9 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.3 5.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 7.3 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 5.3 0.3 0.0 0.2 27.2 RNASE8 RAE2 ENSG00000173431 "Ribonuclease A family member 8" Q8TDE3 14 21057822-21058455 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 229 "salivary gland: 54.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 54.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASE9 "h461, RAK1" ENSG00000188655 "Ribonuclease A family member 9 (inactive)" P60153 14 20556093-20560931 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 985 "epididymis: 98.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RNASET2 "bA514O12.3, FLJ10907, RNASE6PL" ENSG00000026297 "Ribonuclease T2" O00584 6 166922113-166957191 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Lyase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 490.2;Glandular and luminal cells: 761.3;Hofbauer cells: 382.2;Kupffer cells: 484.7;Macrophages: 418.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 497.9" "HPA029013, HPA066509" Approved "Secreted to blood" NA NA 15000000 "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA029013: AB_10602922, HPA066509: AB_2685682" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.13e-2)" "unprognostic (9.33e-2)" "unprognostic (1.76e-2)" "unprognostic (1.30e-1)" "unprognostic (1.15e-2)" "unprognostic (8.11e-2)" "unprognostic (1.79e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.70e-14)" "unprognostic (5.03e-2)" "unprognostic (7.34e-2)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" 34.9 35.0 50.1 68.6 50.4 124.3 50.2 52.2 65.9 161.5 52.3 74.0 57.6 49.1 140.7 24.8 134.6 69.6 19.8 49.5 53.5 31.2 52.4 47.2 117.4 68.2 54.3 36.2 144.7 40.7 26.3 43.5 66.2 51.9 89.9 8.3 112.8 94.1 7.3 25.4 65.4 27.8 61.9 195.1 72.9 13.3 59.1 43.8 76.7 12.1 86.9 54.9 32.2 79.8 12.8 14.2 12.6 37.8 57.0 40.6 8.4 15.8 21.2 7.3 7.4 33.7 19.9 11.1 149.8 41.3 16.7 41.0 20.8 18.6 4.3 15.9 35.1 10.2 20.6 84.6 19.1 152.7 37.3 23.9 33.6 4.3 2.7 30.4 10.1 21.7 20.9 94.5 10.9 44.9 12.6 109.5 6.4 140.0 13.0 25.0 16.6 131.7 136.3 9.9 4.4 28.7 32.0 100.4 8.3 22.3 13.1 497.9 19.3 14.9 9.8 43.7 13.5 15.0 19.5 1.4 32.3 149.2 10.3 116.9 185.6 674.8 29.1 277.0 53.4 136.7 159.9 72.3 226.4 119.6 128.4 41.4 438.9 30.7 368.8 369.3 90.8 179.8 50.1 50.4 52.2 65.9 49.5 53.5 68.2 54.3 66.2 61.9 59.1 79.8 21.8 19.2 29.3 10.1 270.1 43.3 116.4 45.1 72.3 10.5 97.0 95.1 9.5 47.1 28.0 38.6 0.0 63.4 286.8 133.7 23.5 59.2 10.3 490.2 78.9 44.9 75.4 27.6 13.6 27.4 58.8 45.8 80.0 761.3 71.7 38.6 19.2 20.0 382.2 13.5 37.1 204.0 24.4 484.7 187.7 11.3 35.4 418.2 58.7 113.4 146.1 24.4 64.9 14.6 1.7 74.1 324.8 29.3 158.6 61.2 178.5 19.6 19.0 7.1 26.3 31.9 18.6 10.0 23.1 58.3 34.5 27.8 149.2 15.3 193.0 103.9 RNLS "C10orf59, FLJ11218, renalase" ENSG00000184719 "Renalase, FAD dependent amine oxidase" Q5VYX0 10 88273864-88584530 "Enzymes, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 103.0;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 61.8;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 18.3;fHDF/TERT166: 17.1;HSkMC: 19.5" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 10500000000 "Cluster 7: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.27e-2)" "unprognostic (9.16e-2)" "unprognostic (1.27e-1)" "unprognostic (2.58e-1)" "unprognostic (1.46e-3)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (3.98e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (7.74e-3)" "unprognostic (1.37e-2)" "unprognostic (9.80e-2)" "unprognostic (1.71e-1)" 7.1 13.4 2.0 2.8 2.4 2.2 6.7 6.1 3.5 7.4 7.2 7.6 5.5 5.0 5.3 4.9 6.1 5.5 11.8 2.0 2.9 16.6 8.7 3.0 3.8 5.0 6.6 5.8 8.2 9.0 5.3 2.0 5.2 7.0 8.3 4.8 6.0 3.9 11.8 4.3 5.6 3.5 3.4 2.8 6.7 5.3 2.7 2.5 9.1 9.8 4.0 4.7 4.4 3.2 18.3 8.2 0.3 0.1 2.4 2.8 0.0 5.1 0.5 2.7 2.3 1.0 5.2 0.0 8.0 17.1 0.0 2.4 0.0 0.9 2.2 3.8 0.1 2.9 5.1 0.2 11.2 0.0 0.5 19.5 1.4 10.2 0.1 0.3 5.7 0.1 1.4 9.2 0.1 6.3 0.0 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 4.3 0.1 0.1 4.0 12.4 4.9 2.2 8.9 1.3 2.5 4.1 6.3 3.9 5.3 8.4 0.2 0.0 9.8 0.0 0.0 2.1 1.2 2.3 3.6 1.7 2.4 1.7 1.6 3.1 2.2 1.8 1.4 0.1 2.7 2.3 2.7 0.9 1.8 2.0 2.4 6.1 3.5 2.0 2.9 5.0 6.6 5.2 3.4 2.7 3.2 1.2 3.2 1.5 32.0 5.5 3.2 6.8 5.7 4.0 6.5 5.5 3.9 16.7 4.3 5.8 1.8 2.1 2.0 3.2 6.2 23.5 6.4 8.9 3.8 3.1 1.3 5.4 4.6 103.0 9.6 0.5 6.2 7.1 3.2 1.3 2.2 2.5 10.1 6.5 5.0 101.1 5.5 2.0 4.7 3.8 4.3 1.5 3.8 3.6 40.3 3.7 6.8 3.1 51.8 61.8 4.2 8.9 6.4 3.9 4.4 8.5 43.1 1.6 5.7 0.0 4.6 4.6 4.7 8.2 10.4 5.5 1.6 3.0 2.9 7.2 6.9 RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 201.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 19.8;granulocytes: 22.9;monocytes: 29.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036074, HPA036075, HPA061487" Approved Approved "Golgi apparatus" "Secreted - unknown location" NA NA 7800000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA036074: AB_2674926, HPA036075: AB_10672999, HPA061487: AB_2684537" "unprognostic (8.57e-2)" "unprognostic (3.43e-2)" "unprognostic (2.81e-1)" "unprognostic (5.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.95e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-3)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (1.91e-1)" "unprognostic (6.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.68e-1)" 25.2 31.1 8.0 22.8 8.3 25.2 25.8 8.1 8.5 26.7 16.1 53.6 68.5 25.6 39.0 53.8 40.6 22.3 14.7 8.5 8.7 25.9 32.4 30.5 22.1 9.9 9.1 23.4 34.1 25.4 13.3 27.5 9.1 25.9 57.0 4.2 38.3 27.6 18.8 37.0 58.1 28.1 9.1 33.4 28.5 17.9 10.6 21.7 33.2 12.7 26.5 23.3 28.8 11.8 66.2 71.0 40.8 62.7 65.1 61.3 102.1 49.5 95.6 60.9 67.6 51.8 83.1 14.3 61.8 87.8 38.0 117.4 52.5 97.2 42.4 39.1 67.6 35.5 32.5 48.7 55.1 92.3 121.3 55.9 97.9 54.1 62.0 74.7 110.6 34.8 82.5 21.6 62.1 61.0 12.8 40.2 58.4 105.4 34.4 48.3 57.5 101.6 128.7 61.2 46.9 39.9 122.2 155.9 52.1 78.9 116.6 52.4 79.9 28.9 38.0 28.7 61.3 45.3 39.6 12.9 27.8 77.3 58.1 22.9 14.9 22.1 3.0 25.9 4.1 2.5 3.2 3.4 19.8 4.6 2.8 3.2 11.0 2.9 29.9 7.2 5.4 4.0 8.0 8.3 8.1 8.5 8.5 8.7 9.9 9.1 9.1 9.1 10.6 11.8 26.7 9.6 21.5 8.5 19.7 28.8 40.5 31.2 40.5 15.5 32.8 33.1 12.2 38.6 26.7 25.8 10.4 116.6 21.4 136.6 19.6 71.1 5.4 35.9 17.7 26.1 44.9 19.0 12.7 51.2 91.1 26.1 45.3 21.5 15.2 23.2 27.1 51.4 103.7 11.8 11.1 71.9 14.2 81.0 39.4 4.9 25.4 72.9 24.9 15.0 86.7 12.6 17.5 5.5 8.1 47.8 83.4 23.0 23.6 25.0 201.7 65.8 39.1 8.0 26.3 11.4 28.2 22.7 9.5 53.6 21.6 87.6 17.7 33.2 86.6 34.8 RPTN FLJ39117 ENSG00000215853 Repetin Q6XPR3 1 152153595-152159228 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 52.2;skin 1: 29.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "head and neck cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030483, HPA030485" Enhanced "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA030483: AB_2673495, HPA030485: AB_10601159" "unprognostic (1.37e-2)" "unprognostic (5.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.54e-2)" "unprognostic (4.00e-2)" "unprognostic (5.23e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 29.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 52.2 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 RS1 "RS, XLRS1" ENSG00000102104 "Retinoschisin 1" O15537 X 18639688-18672108 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 207 "retina: 213.7" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 160.6;Rod photoreceptor cells: 162.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059546 Enhanced "Secreted in other tissues" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA059546: AB_2684058" "unprognostic (8.31e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (4.80e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-2)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.77e-3)" "unprognostic (4.14e-1)" "unprognostic (7.03e-2)" "unprognostic (1.06e-1)" "unprognostic (3.06e-2)" "unprognostic (5.12e-2)" "unprognostic (2.04e-4)" 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 213.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 6.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 1.9 0.0 0.0 0.0 160.6 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 162.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 RSPO1 "FLJ40906, RSPONDIN" ENSG00000169218 "R-spondin 1" Q2MKA7 1 37611350-37634892 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 28.9;endometrium 1: 41.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 7.7;Breast myoepithelial cells: 15.6;Fibroblasts: 5.4;Langerhans cells: 2.9" "Cancer enriched" "Detected in some" 13 "ovarian cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;THP-1: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046154, HPA062923" Uncertain Approved Vesicles "Secreted in female reproductive system" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA046154: AB_10964912, HPA062923: " "unprognostic (1.50e-2)" "unprognostic (1.97e-3)" "unprognostic (5.99e-3)" "unprognostic (2.22e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-6)" "unprognostic (1.84e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.76e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-2)" 11.3 0.1 0.0 0.8 0.1 0.1 7.9 0.1 0.1 28.9 0.0 1.8 1.1 41.4 2.2 3.1 20.0 2.7 0.7 0.1 0.0 0.8 0.1 4.0 1.9 0.1 0.1 2.1 0.5 0.1 0.1 0.4 0.1 6.7 0.5 0.1 1.3 1.8 0.0 6.6 3.3 13.1 0.0 0.8 4.0 0.2 0.1 0.0 0.0 0.5 3.0 1.5 19.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 7.7 15.6 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.1 0.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.4 0.1 0.3 0.0 0.0 0.1 RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 75.3;Inhibitory neurons: 86.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;U-266/70: 4.2" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" 0.2 0.0 2.8 0.7 4.4 0.1 0.0 1.3 16.2 3.4 2.6 13.9 3.4 0.0 1.7 5.9 0.0 3.2 0.2 6.6 13.2 0.0 0.4 7.1 0.0 2.6 23.0 0.3 0.0 0.0 2.9 17.3 2.0 8.7 7.8 0.3 0.0 2.3 0.0 0.0 4.6 0.3 2.1 0.0 7.6 0.7 3.5 0.0 0.0 0.0 0.0 1.7 0.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.4 1.3 16.2 6.6 13.2 2.6 23.0 2.0 2.1 3.5 6.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.3 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 86.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 4.7 0.0 0.0 0.0 4.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.7 0.0 0.0 1.0 0.0 0.2 0.0 0.0 RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 18.5;Endothelial cells: 42.4;Fibroblasts: 73.0;Hepatic stellate cells: 26.4;Inhibitory neurons: 17.8;Leydig cells: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 21.9;BJ hTERT+: 3.6;hTERT-RPE1: 6.3;U-138 MG: 4.6;U-87 MG: 4.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 33: Fibroblasts - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" 30.9 15.1 2.1 16.1 2.4 0.0 12.4 3.3 4.9 13.8 0.0 7.4 2.2 51.4 28.4 5.4 25.3 11.1 0.9 8.5 1.5 4.0 6.5 5.1 3.7 1.6 1.4 3.6 1.6 0.1 3.1 35.4 0.3 6.3 6.6 0.1 5.4 20.0 39.8 2.8 10.3 48.1 0.0 1.8 13.3 1.0 1.0 2.4 3.6 5.0 1.4 8.6 7.1 0.9 0.0 21.9 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 6.3 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.6 1.8 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 3.3 4.9 8.5 1.5 1.6 1.4 0.3 0.0 1.0 0.9 3.6 0.0 0.0 0.7 0.1 0.9 0.1 0.0 0.6 1.5 0.2 0.9 0.5 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.4 12.3 0.3 18.5 42.4 0.0 0.0 5.9 0.0 1.1 73.0 5.1 0.3 0.0 0.0 26.4 0.4 1.6 0.0 17.8 0.0 0.0 1.0 0.8 2.2 27.4 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.2 6.6 2.1 3.5 0.1 0.4 0.4 0.1 1.6 0.1 0.1 0.0 0.2 RSPO4 "C20orf182, dJ824F16.3" ENSG00000101282 "R-spondin 4" Q2I0M5 20 958452-1002311 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.0;lung: 12.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Early spermatids: 6.6;Late spermatids: 7.3;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.0;EFO-21: 2.0;fHDF/TERT166: 2.4;NTERA-2: 6.3;SK-BR-3: 4.3;U-2 OS: 6.9" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" HPA048887 Uncertain "Secreted in other tissues" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "HPA048887: AB_2680545" "unprognostic (2.36e-1)" "unprognostic (3.60e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (2.98e-6)" "unprognostic (8.93e-2)" "unprognostic (1.14e-3)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (6.50e-2)" "unprognostic (2.02e-2)" "unprognostic (5.26e-3)" "unprognostic (2.96e-1)" "unprognostic (5.68e-9)" "unprognostic (6.65e-3)" "unprognostic (4.41e-2)" "unprognostic (6.18e-3)" "unprognostic (2.22e-2)" 0.3 0.2 4.3 0.6 4.6 0.0 1.3 2.1 6.7 0.6 1.1 0.3 0.1 0.3 1.4 0.8 1.6 0.4 0.5 3.4 7.6 0.6 0.3 12.6 0.0 13.0 8.4 0.4 0.3 0.3 2.1 0.2 12.6 0.4 0.0 1.2 0.4 0.2 0.1 3.0 0.3 0.0 3.8 0.2 0.2 3.2 9.6 0.0 3.0 0.0 0.4 0.2 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.2 0.0 0.1 0.0 0.0 0.0 0.8 2.0 2.4 0.3 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 4.3 0.0 0.0 0.1 0.0 0.0 0.0 6.9 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 4.6 2.1 6.7 3.4 7.6 13.0 8.4 12.6 3.8 9.6 2.2 0.0 0.0 0.0 10.7 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.3 0.0 0.0 2.9 0.0 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.8 7.3 0.0 0.0 1.8 1.9 0.0 0.1 0.0 8.5 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 2.1 0.9 0.0 0.4 0.3 0.0 0.0 0.0 0.0 RSPRY1 KIAA1972 ENSG00000159579 "Ring finger and SPRY domain containing 1" Q96DX4 16 57186137-57240469 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003729 Approved "Secreted to blood" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA003729: AB_10964215" "unprognostic (2.73e-2)" "unprognostic (7.10e-2)" "unprognostic (1.32e-3)" "unprognostic (5.32e-2)" "unprognostic (1.63e-3)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.84e-2)" "unprognostic (1.36e-1)" "unprognostic (4.63e-2)" "unprognostic (1.29e-1)" "unprognostic (2.26e-2)" "unprognostic (1.01e-1)" "unprognostic (4.89e-2)" "unprognostic (4.68e-2)" "unprognostic (3.35e-1)" "unprognostic (6.47e-2)" "unprognostic (4.81e-3)" 10.1 8.9 8.8 10.1 10.1 7.0 13.2 9.4 9.5 15.1 19.0 14.4 16.0 13.1 12.6 11.7 11.6 16.0 8.6 8.2 9.1 16.1 19.7 9.5 13.4 10.0 9.7 14.4 18.5 15.3 8.3 15.1 9.3 13.8 16.2 8.5 11.5 14.0 9.1 9.7 16.2 15.3 8.6 9.7 13.4 21.8 10.6 17.5 17.3 10.6 17.3 16.1 9.2 11.7 17.0 25.7 39.5 20.4 24.6 30.8 23.5 29.7 30.5 39.1 31.0 27.4 21.8 23.8 37.6 39.7 27.0 21.6 34.7 28.6 44.4 16.2 14.4 12.7 18.9 39.5 32.1 22.7 33.5 37.3 27.7 38.4 53.6 29.6 53.5 27.2 21.3 9.6 34.3 9.9 38.7 15.3 25.6 28.4 29.1 48.9 27.2 22.0 46.6 17.1 13.4 29.8 47.8 17.8 12.3 22.4 17.5 22.9 37.8 27.9 27.2 17.6 24.6 25.0 24.7 38.6 24.5 22.0 30.3 27.6 22.5 30.1 24.8 24.7 22.6 26.1 22.7 22.9 26.0 24.0 26.2 25.2 24.5 26.4 36.3 16.5 30.0 18.2 8.8 10.1 9.4 9.5 8.2 9.1 10.0 9.7 9.3 8.6 10.6 11.7 18.6 32.1 13.1 22.5 24.0 34.0 21.0 27.5 38.7 17.1 28.5 17.3 17.5 42.9 23.2 18.4 10.4 26.9 18.9 27.4 25.4 25.2 107.2 22.2 36.7 23.8 21.5 24.8 22.0 23.4 37.7 29.2 25.5 28.9 10.8 31.1 22.5 41.8 17.3 15.2 25.6 32.9 28.5 22.9 23.8 65.9 20.2 19.8 14.2 19.7 25.1 19.7 15.5 36.2 35.8 25.5 15.5 21.4 21.2 29.1 29.5 28.1 23.3 18.2 6.6 25.5 25.2 60.9 52.3 27.9 37.1 27.9 21.8 37.7 23.5 23.0 RTBDN FLJ36353 ENSG00000132026 Retbindin Q9BSG5 19 12825478-12835428 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 288.0" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 350.3;Rod photoreceptor cells: 524.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 8.3;SH-SY5Y: 5.4;U-266/84: 23.1;U-87 MG: 4.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA052511 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA052511: AB_2797243" "unprognostic (4.55e-4)" "unprognostic (3.94e-3)" "unprognostic (2.18e-1)" "unprognostic (1.54e-4)" "unprognostic (3.33e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" "unprognostic (2.45e-2)" "unprognostic (2.02e-2)" "unprognostic (3.55e-1)" "unprognostic (6.48e-2)" "unprognostic (7.04e-3)" "unprognostic (7.66e-9)" "unprognostic (3.55e-2)" "unprognostic (1.00e-1)" "unprognostic (7.05e-2)" "unprognostic (2.24e-2)" 0.0 3.5 5.1 0.1 5.9 0.2 0.0 1.9 10.0 0.0 0.9 1.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 6.7 2.7 0.0 0.0 0.1 0.0 2.7 1.9 0.0 1.2 0.3 34.3 0.0 5.8 0.0 0.3 288.0 0.0 0.0 0.0 0.1 0.5 0.1 0.9 0.0 1.1 3.3 2.9 8.7 0.0 0.0 0.0 0.0 0.1 3.2 0.9 0.1 0.1 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.9 0.9 0.0 0.6 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.1 2.4 0.0 0.0 0.4 0.2 0.0 0.0 0.1 1.3 2.7 0.0 0.1 0.1 0.0 0.9 0.7 1.1 0.7 0.1 1.1 0.1 0.0 8.3 5.4 0.1 0.0 0.4 0.4 2.8 0.7 0.0 0.8 1.0 0.7 0.1 1.2 23.1 4.3 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.1 5.9 1.9 10.0 6.7 2.7 2.7 1.9 5.8 0.9 2.9 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 50.5 0.0 0.0 1.4 0.0 0.1 0.0 350.3 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.0 1.8 0.0 0.0 2.8 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 2.5 0.6 4.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 84.4 0.0 1.0 0.7 0.1 0.1 0.0 0.5 0.0 0.7 0.1 0.0 524.0 0.0 0.1 0.0 16.2 5.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 S100A12 "CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6" ENSG00000163221 "S100 calcium binding protein A12" P80511 1 153373711-153375621 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3489.7" "Group enriched" "Detected in many" 20 "Kupffer cells: 711.7;Macrophages: 475.0;monocytes: 998.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 51.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 1321.1;neutrophil: 1781.4" "Group enriched" "Detected in many" 13 "granulocytes: 1781.4;monocytes: 1321.1" "Cell line enhanced" "Detected in some" "hTCEpi: 2.6;THP-1: 1.6" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "HPA002881, CAB025872" Enhanced "Secreted to blood" NA NA 28500000 8300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB025872: , HPA002881: AB_1848175" "unprognostic (1.33e-1)" "unprognostic (4.51e-2)" "unprognostic (7.49e-2)" "unprognostic (1.36e-1)" "unprognostic (7.30e-2)" "unprognostic (4.36e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-3)" "unprognostic (9.04e-2)" "unprognostic (3.14e-2)" "unprognostic (1.58e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (5.03e-4)" "unprognostic (3.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.31e-2)" "unprognostic (7.70e-2)" 54.9 3.2 2.6 82.0 3.1 3489.7 7.0 2.9 7.7 21.9 3.2 5.5 1.7 2.1 0.0 52.4 19.3 6.7 16.6 2.7 2.6 15.2 25.6 148.4 1.9 3.2 2.9 2.1 3.6 1.3 4.3 19.8 3.9 3.5 0.4 0.3 11.4 0.2 4.0 3.7 4.4 40.4 3.0 523.2 8.9 0.9 2.9 30.2 6.0 14.8 46.5 41.9 33.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1321.1 5.2 1.9 44.9 1.0 3.2 0.8 1.5 122.7 1.0 1.1 0.5 1781.4 0.4 9.6 8.3 2.0 1031.8 2.6 3.1 2.9 7.7 2.7 2.6 3.2 2.9 3.9 3.0 2.9 2.9 0.0 19.2 24.4 0.0 6.1 0.1 0.3 9.8 0.0 0.0 0.1 0.0 1.1 8.6 9.2 1.8 0.0 0.5 2.9 0.0 0.0 0.1 1.4 0.0 0.0 2.1 0.0 14.1 0.1 0.2 0.9 4.1 1.1 0.0 13.9 0.0 6.8 3.8 8.6 0.0 0.1 0.0 0.0 711.7 0.8 1.8 0.0 475.0 0.0 1.0 998.3 0.0 36.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.7 7.8 0.0 0.0 0.8 0.4 0.0 0.2 5.7 0.0 0.5 6.9 0.0 0.1 0.2 S100A13 ENSG00000189171 "S100 calcium binding protein A13" Q99584 1 153618787-153631360 "Predicted intracellular proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 3084.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 28.3" "Group enriched" "Detected in all" 5 "dendritic cells: 11.9;NK-cells: 28.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 811.3;SuSa: 896.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019592, CAB025494" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 36000 "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "CAB025494: , HPA019592: AB_10601499" "unprognostic (1.50e-2)" "unprognostic (9.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (7.77e-2)" "unprognostic (9.72e-3)" "unprognostic (1.75e-3)" "unprognostic (9.93e-2)" "unprognostic (6.48e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.83e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-2)" 275.3 137.3 237.4 47.7 247.3 4.4 222.4 241.0 347.5 133.7 214.6 198.9 30.6 111.8 72.1 91.7 129.8 103.9 310.1 233.1 240.8 262.2 66.2 138.0 48.8 252.9 245.5 138.2 75.7 317.4 73.9 70.1 249.4 100.9 59.8 25.8 156.1 64.6 250.6 114.0 116.5 68.9 245.8 111.7 94.4 41.2 251.6 21.2 318.7 220.6 49.6 121.2 122.7 258.6 188.7 153.7 174.5 111.4 150.7 437.5 62.7 254.7 400.0 150.6 172.2 150.4 203.7 4.9 471.6 435.5 22.3 174.7 73.5 158.7 132.7 0.8 68.1 12.0 178.0 129.6 99.8 5.9 39.2 355.3 59.4 135.3 145.0 441.9 346.5 1.3 61.4 0.3 475.2 663.4 0.4 3.4 141.0 161.1 460.2 30.0 180.4 1.4 811.3 141.9 53.4 2.0 544.7 277.2 576.7 896.9 226.4 6.8 495.0 103.3 57.9 139.5 312.0 2.0 5.3 9.3 185.5 3.2 62.1 4.1 2.0 0.2 0.4 0.9 0.9 4.1 0.4 0.3 7.0 2.0 0.6 0.5 0.3 28.3 1.4 11.9 1.4 1.1 237.4 247.3 241.0 347.5 233.1 240.8 252.9 245.5 249.4 245.8 251.6 258.6 331.0 28.9 106.1 29.7 9.3 110.5 177.4 105.0 103.0 2.1 311.2 345.6 141.9 164.5 104.0 465.3 0.0 132.4 15.3 148.7 248.4 323.3 8.4 399.3 449.1 251.9 124.7 17.3 1.2 323.6 202.1 450.0 58.6 573.8 23.5 185.5 372.3 51.8 162.3 0.0 0.5 167.5 61.1 31.7 107.7 36.3 771.7 37.1 238.3 13.1 14.8 308.1 1.0 0.0 8.8 488.4 164.7 314.1 6.3 240.0 128.7 521.7 77.1 6.9 0.0 234.2 132.5 12.8 23.4 80.3 75.7 74.7 20.5 3084.7 100.6 244.3 S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 2708.8;Langerhans cells: 5952.7;Macrophages: 2786.0;monocytes: 3172.6;NK-cells: 2130.8;Skeletal myocytes: 2034.0;T-cells: 2111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 2614.3;ASC diff: 3300.1;BJ hTERT+: 6738.6;fHDF/TERT166: 4819.1;RPMI-8226: 2700.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.6" "CAB002618, HPA007486, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 9600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007486: , HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" 982.3 77.1 25.5 353.9 26.2 1090.8 561.9 27.5 53.1 566.3 32.0 301.7 91.7 177.8 124.5 224.0 217.6 167.6 268.5 24.7 27.4 247.0 64.3 874.2 221.0 31.7 26.4 51.0 53.8 18.1 24.8 182.9 29.8 223.7 331.5 10.0 245.4 155.8 163.0 371.5 234.3 297.7 27.8 443.0 133.3 32.2 33.7 112.6 191.9 424.6 315.4 391.6 455.2 34.1 11.8 2614.3 13.2 77.0 3300.1 2410.9 3.7 1664.4 6738.6 32.1 148.4 20.0 180.3 0.8 299.7 4819.1 3.5 65.3 8.8 20.9 23.6 405.2 2.3 1186.8 529.0 59.4 4.3 106.9 1924.6 364.2 21.5 62.2 13.0 4.9 2.6 0.7 9.9 4.2 2468.1 10.6 3.8 1273.9 7.2 189.7 1050.4 64.1 3.7 2700.2 103.5 71.3 108.5 11.6 24.9 1286.6 9.4 412.5 77.1 1493.7 3.1 8.5 13.7 2159.5 9.3 82.8 647.5 14.3 6.1 1367.9 127.2 2789.7 13536.2 1408.0 5800.5 9099.6 6077.0 761.6 5167.7 4700.0 9268.4 282.5 882.4 2641.3 12129.7 837.1 11862.4 1626.0 7406.7 24075.8 25.5 26.2 27.5 53.1 24.7 27.4 31.7 26.4 29.8 27.8 33.7 34.1 226.0 490.4 398.4 0.0 266.1 772.9 19.5 159.0 93.9 0.7 44.9 65.9 14.9 35.8 273.8 893.8 0.0 52.4 1345.4 8.9 111.6 21.9 7.3 53.0 473.0 209.1 4.8 730.9 0.0 23.5 255.5 1378.8 54.0 41.9 1395.8 0.6 96.4 18.6 1966.1 45.4 0.0 10.0 345.8 2708.8 5952.7 24.0 235.8 2786.0 1193.5 12.2 3172.6 3.6 2130.8 0.0 0.1 35.7 17.0 45.9 266.5 12.9 3.2 19.7 154.9 2.3 151.2 2034.0 1309.6 1.9 5.5 77.6 694.0 53.4 2111.1 32.5 11.3 73.1 S100A7 "PSOR1, S100A7c" ENSG00000143556 "S100 calcium binding protein A7" P31151 1 153457744-153460651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 1065.7;lymphoid tissue: 1239.6;skin 1: 346.5;vagina: 1020.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 59.3;Club cells: 70.4;Ionocytes: 18.3;Suprabasal keratinocytes: 89.6;Syncytiotrophoblasts: 26.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 1201.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 7.2;SK-BR-3: 16.9" "CAB001453, HPA006997, CAB033766" Enhanced Uncertain Cytosol "Secreted in other tissues" NA NA 14000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB001453: AB_564004, CAB033766: AB_2269963, HPA006997: AB_1079860" "unprognostic (3.28e-1)" "unprognostic (9.85e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-2)" "unprognostic (3.17e-1)" "unprognostic (2.94e-2)" "unprognostic (1.03e-2)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (2.99e-1)" "unprognostic (5.41e-2)" "unprognostic (1.21e-2)" 1.0 0.2 0.9 0.0 0.8 0.8 15.6 1.4 2.1 174.8 0.7 0.3 0.0 1.2 27.6 1065.7 0.3 0.2 0.5 0.8 0.8 0.1 0.5 0.4 0.2 0.9 0.8 0.5 0.4 0.0 0.2 0.2 0.8 0.5 0.0 0.0 55.5 0.2 0.4 346.5 0.2 1.4 0.8 0.3 0.4 0.3 0.7 12.4 0.2 0.0 1239.6 1.2 1020.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 7.2 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.7 16.9 0.0 0.9 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 1.4 2.1 0.8 0.8 0.9 0.8 0.8 0.8 0.7 1.1 0.0 0.0 0.0 0.0 0.0 11.7 0.2 59.3 0.0 0.0 1.1 0.0 0.0 0.0 70.4 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 1.9 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 6.3 0.0 0.0 0.0 4.7 0.2 0.2 3.8 89.6 26.4 0.1 8.4 0.6 0.4 S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 4126.5;Kupffer cells: 6348.0;Macrophages: 3758.3;monocytes: 6932.6;Squamous epithelial cells: 8480.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in some" 24 "hTCEpi: 241.8;SK-BR-3: 719.0;THP-1: 400.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" 582.3 54.3 41.7 1245.8 45.6 35382.0 70.0 43.4 88.0 5650.6 45.5 55.2 15.4 23.1 5.5 24565.6 236.1 99.0 121.1 40.9 42.7 103.0 176.7 1061.7 29.5 47.7 44.8 25.8 52.0 9.6 41.7 205.8 50.7 43.1 14.7 5.6 3988.2 5.0 48.5 267.3 47.7 430.2 44.2 3239.5 93.8 16.2 45.5 281.3 48.8 174.8 8952.6 561.9 11166.4 46.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.0 1.3 0.0 0.3 12.4 0.0 18.7 0.0 0.1 0.0 3.5 0.0 0.0 0.0 5.6 0.1 0.0 241.8 0.0 7.5 0.0 0.0 0.0 9.6 1.2 0.0 0.9 0.4 1.5 0.3 0.0 0.0 0.4 5.8 1.0 0.0 0.0 0.4 0.5 3.6 719.0 0.0 0.0 4.7 400.6 10.6 0.0 0.2 0.9 0.1 0.2 1.3 2.7 0.3 13.9 0.0 848.0 26833.7 3023.7 33.4 1999.2 49.2 57.2 21.8 18.2 4686.1 23.5 21.6 23.3 52973.6 27.1 493.1 188.1 37.1 24979.9 41.7 45.6 43.4 88.0 40.9 42.7 47.7 44.8 50.7 44.2 45.5 46.2 1.1 224.4 489.8 0.0 77.2 19.6 3.5 4126.5 50.7 0.0 13.2 3.9 10.0 70.1 817.0 14.7 0.0 5.8 67.1 0.3 0.0 1.0 210.7 0.5 0.6 33.1 0.0 143.5 0.0 0.9 8.5 61.3 1.1 0.5 227.1 0.1 76.1 54.6 417.5 0.0 0.0 0.2 207.5 6348.0 5.1 172.4 4.1 3758.3 0.0 0.0 6932.6 0.0 289.4 0.0 0.0 1.4 0.0 1.5 26.1 0.9 0.0 25.0 162.8 0.0 0.0 7.7 32.3 2.1 1.0 8480.1 113.2 6.7 91.4 0.0 0.0 31.3 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 SAA1 "PIG4, SAA, TP53I4" ENSG00000173432 "Serum amyloid A1" P0DJI8 11 18266260-18269977 "Disease related genes, Predicted secreted proteins" "Acute phase" Heparin-binding Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 48144.3" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 99298.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 1249.6" "Group enriched" "Detected in some" 5 "midbrain: 3.8;pons: 2.6;thalamus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 716.4" "Secreted to blood" NA NA 300000000 11000000000 "Cluster 7: Monocytes - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (1.50e-1)" "unprognostic (4.54e-3)" "unprognostic (1.79e-2)" "unprognostic (1.63e-2)" "unprognostic (7.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-2)" "unprognostic (8.95e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.57e-12)" "unprognostic (5.15e-2)" "unprognostic (9.78e-2)" "unprognostic (9.23e-3)" "unprognostic (1.64e-1)" 2040.4 54.4 0.1 161.7 0.2 0.0 1382.7 0.1 0.6 258.0 1.8 40.3 1.4 2.2 0.2 51.1 56.6 33.6 23.2 0.3 0.3 29.5 48144.3 98.5 1.1 0.8 3.8 3.3 46.7 0.5 66.6 7.2 2.6 66.5 6.4 0.0 2368.1 4.4 511.6 88.6 75.0 18.8 0.1 38.8 42.0 1.7 6.0 52.1 18.1 0.2 15.7 63.9 29.0 0.1 49.2 0.3 0.0 0.3 34.4 0.2 18.9 1.3 1.1 0.2 0.3 0.1 17.2 0.0 38.3 0.0 11.7 45.5 0.0 716.4 0.3 0.6 0.0 0.8 0.0 0.1 148.4 1.1 0.0 60.9 66.7 0.2 76.7 0.1 0.0 0.0 0.1 0.0 9.3 0.1 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 28.5 0.9 0.0 0.1 4.2 5.5 0.2 0.0 0.5 0.0 0.0 0.2 5.5 0.0 1.3 0.0 1.3 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.3 0.3 0.8 3.8 2.6 0.1 6.0 0.1 107.2 6.4 2.8 0.0 259.8 9.3 64.9 10039.5 10.2 0.0 210.6 1010.4 0.1 1701.5 7604.7 55.2 0.0 1.3 3.0 44.5 0.0 250.4 0.0 12.6 1.6 114.9 1.8 3543.7 0.1 81.1 34.4 8.3 0.0 14.3 2.5 0.0 2568.6 99298.7 1.0 0.0 0.1 5.2 2012.1 2454.9 0.3 0.0 0.0 2.6 51.6 0.0 2.6 0.0 1.0 0.0 0.1 68.8 5.5 0.0 0.1 185.5 3.1 0.2 15716.2 0.0 0.0 31.5 736.1 0.0 0.0 34.1 0.1 2.1 214.7 0.0 36.7 178.8 SAA2 ENSG00000134339 "Serum amyloid A2" P0DJI9 11 18239223-18248668 "Disease related genes, Predicted secreted proteins" "Acute phase" Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 36265.6" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 55342.6" "Cancer enriched" "Detected in many" 22 "liver cancer: 150.5" "Group enriched" "Detected in some" 9 "midbrain: 6.3;pons: 4.8;thalamus: 7.7" "Immune cell enhanced" "Detected in some" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 27.8;EFO-21: 20.2;GAMG: 19.6;HaCaT: 25.0;HBEC3-KT: 55.4;HSkMC: 17.6" "Secreted to blood" NA NA 9200000000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.73e-3)" "unprognostic (4.42e-2)" "unprognostic (2.63e-1)" "unprognostic (5.03e-2)" "unprognostic (1.40e-3)" "unprognostic (7.12e-2)" "unprognostic (7.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.57e-1)" "unprognostic (2.86e-2)" "unprognostic (2.78e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (1.53e-1)" "unprognostic (9.72e-2)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" 562.3 16.9 0.0 137.9 0.1 0.4 321.5 0.5 0.7 277.0 0.6 11.5 0.9 1.0 0.2 22.1 21.1 14.0 8.3 0.1 0.1 12.8 36265.6 35.7 0.6 0.2 6.3 1.7 13.9 0.2 31.1 1.7 4.8 38.5 1.3 0.6 1796.2 1.6 221.2 25.7 21.0 6.5 0.0 20.1 18.1 2.1 7.7 16.3 6.6 0.2 6.8 22.4 7.8 0.7 27.8 0.1 0.2 0.2 1.0 0.0 3.6 0.1 0.8 0.1 0.3 0.0 12.1 0.1 20.2 0.2 19.6 25.0 0.0 55.4 0.1 1.2 0.0 1.0 0.5 0.0 7.8 0.8 0.1 17.6 7.4 0.0 8.9 0.6 0.2 0.0 0.0 0.9 1.5 0.0 0.2 0.0 0.5 0.4 0.0 0.2 0.7 0.0 12.4 1.3 0.3 0.0 1.7 8.5 0.1 0.5 0.4 0.5 0.2 0.2 1.2 0.5 1.2 0.5 0.3 1.7 0.1 1.1 0.3 1.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.4 0.1 0.1 1.1 0.1 0.2 0.2 0.2 0.1 0.0 0.1 0.5 0.7 0.1 0.1 0.2 6.3 4.8 0.0 7.7 0.7 7.6 0.0 1.5 0.0 184.4 1.0 5.6 4629.9 0.6 0.0 56.8 68.5 0.2 1052.3 4596.4 3.7 0.0 0.4 0.8 21.9 0.0 70.3 1.6 12.3 0.9 68.2 0.0 2356.0 0.0 34.4 2.3 2.0 0.0 13.5 0.0 0.0 1442.8 55342.6 0.4 0.0 0.0 1.1 1204.4 1502.7 0.0 0.5 0.0 0.6 8.8 0.0 1.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.1 34.5 2.9 0.1 11449.8 0.0 0.0 3.1 400.9 0.3 0.0 5.6 0.1 0.5 144.2 0.0 5.3 65.4 SAA4 "C-SAA, CSAA" ENSG00000148965 "Serum amyloid A4, constitutive" P35542 11 18231355-18236802 "Plasma proteins, Predicted secreted proteins" "Acute phase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 124 "liver: 1943.5" "Group enriched" "Detected in some" 7 "Hepatocytes: 2132.8;Respiratory ciliated cells: 706.8" "Cancer enriched" "Detected in many" 141 "liver cancer: 118.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 28.8" "Not detected" "Not detected" "CAB026061, HPA060139" Supported "Secreted to blood" NA NA 65000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB026061: , HPA060139: AB_2684210" "unprognostic (4.70e-4)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (4.83e-1)" "unprognostic (4.15e-2)" "unprognostic (6.05e-2)" "unprognostic (3.63e-3)" "unprognostic (5.94e-2)" "unprognostic (2.40e-2)" "unprognostic (1.41e-1)" "unprognostic (7.35e-2)" "unprognostic (2.54e-8)" "unprognostic (2.49e-1)" "unprognostic (6.46e-2)" 7.4 0.5 0.3 0.4 0.3 0.0 6.7 0.3 0.6 15.6 0.3 0.2 0.0 0.0 0.2 0.5 0.5 1.0 0.1 0.3 0.3 0.4 1943.5 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.8 0.0 0.3 1.2 0.0 0.1 11.4 0.1 3.4 0.5 0.1 0.1 0.3 1.2 0.1 1.3 0.4 0.9 0.0 0.0 0.2 0.1 0.1 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.3 0.1 28.8 0.3 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.6 0.3 0.3 0.4 0.4 0.3 0.3 0.4 0.5 0.1 0.0 0.0 0.0 2.5 0.0 0.0 184.7 0.0 0.0 2.1 1.4 0.0 18.6 172.6 0.0 0.0 0.0 0.0 3.5 0.0 4.0 0.6 0.4 0.0 1.6 0.0 21.5 0.0 1.2 0.1 0.0 0.0 0.3 0.0 0.0 27.5 2132.8 0.1 0.0 0.0 0.0 71.2 38.0 0.0 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.3 0.0 0.0 706.8 0.0 0.0 0.0 23.6 0.1 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.5 SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1056.2;skin 1: 2444.7;vagina: 756.5" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 1017.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.2;ASC TERT1: 107.5;HSkMC: 146.1;U-2197: 51.6;U-87 MG: 119.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" NA NA 89000000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" 2.9 0.6 0.5 0.1 3.9 0.7 94.3 0.4 1.3 465.7 0.3 1.0 0.0 0.5 0.0 1056.2 0.2 0.3 1.4 0.5 0.4 0.4 1.7 0.9 0.0 0.5 0.4 0.7 1.5 0.0 0.9 0.3 0.5 0.5 0.0 0.0 351.8 0.0 13.1 2444.7 0.7 0.2 0.4 0.5 1.1 1.0 0.5 6.5 0.7 0.0 168.9 1.1 756.5 0.4 0.1 0.1 0.0 0.1 62.2 107.5 0.1 5.1 7.2 2.4 0.9 0.0 0.1 0.1 1.2 4.8 1.7 0.3 0.0 1.8 1.0 0.1 0.2 0.0 0.1 0.0 0.6 0.0 0.1 146.1 8.2 30.0 7.1 2.1 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.4 0.3 0.2 0.0 0.4 18.4 3.8 51.6 1.4 0.5 0.3 0.0 119.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.9 0.4 1.3 0.5 0.4 0.5 0.4 0.5 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 89.3 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.4 0.8 1.8 0.0 0.0 0.2 0.6 0.2 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 4.0 0.0 0.2 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 1.0 0.2 0.2 13.4 1017.6 0.3 0.7 0.0 0.0 0.4 SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 36.5;Collecting duct cells: 42.3;Muller glia cells: 48.5;Peritubular cells: 26.7;Smooth muscle cells: 28.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 7.5;pons: 6.3;spinal cord: 7.7;white matter: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 9.5;RPTEC TERT1: 16.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 40000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA029595: AB_10600763" "prognostic favorable (7.18e-4)" "unprognostic (5.08e-3)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (2.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.65e-2)" "unprognostic (2.92e-1)" "unprognostic (1.46e-1)" "unprognostic (9.54e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (6.14e-2)" "unprognostic (3.54e-1)" "unprognostic (2.12e-2)" "unprognostic (6.25e-2)" 6.4 3.0 0.4 1.4 0.5 0.3 3.4 1.2 0.6 5.2 0.6 4.7 0.9 4.4 4.5 9.5 8.2 1.3 2.3 0.8 0.8 8.3 0.6 3.9 1.5 7.5 0.9 3.3 1.2 0.1 1.6 9.4 6.3 15.1 1.1 9.0 4.6 10.8 0.6 1.9 2.5 8.9 7.7 1.1 9.6 2.6 0.4 0.2 2.5 1.4 0.2 17.9 4.7 16.7 0.2 0.2 0.4 0.5 0.0 0.0 1.3 9.5 0.0 0.0 0.0 0.1 0.2 0.4 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.4 0.3 0.4 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.3 0.0 0.0 0.4 0.3 0.9 0.5 0.2 0.2 0.1 0.0 16.9 0.1 0.5 0.5 1.0 0.4 0.1 3.1 0.2 0.1 0.5 0.1 1.5 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.5 1.2 0.6 0.8 0.8 7.5 0.9 6.3 7.7 0.4 16.7 0.6 9.6 0.0 1.0 0.2 1.3 6.9 0.0 36.5 2.4 5.8 11.6 3.8 4.3 0.0 42.3 2.1 0.2 1.0 0.5 1.9 1.3 10.3 7.2 1.4 1.7 0.0 0.0 0.5 0.0 0.4 13.2 10.7 14.9 0.0 0.2 1.4 0.2 0.4 0.0 0.4 0.2 0.0 0.0 0.4 3.2 12.2 0.4 3.6 0.0 0.0 48.5 0.0 1.0 0.2 0.6 0.0 26.7 0.0 1.8 0.0 3.6 0.0 2.2 6.6 0.9 28.7 11.4 4.4 0.6 1.3 0.4 0.5 0.2 0.1 0.5 SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 360.1;brain: 426.2;pituitary gland: 269.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 212.4;Enteroendocrine cells: 283.4;Inhibitory neurons: 109.9;Ionocytes: 138.4" "Group enriched" "Detected in many" 8 "glioma: 70.0;pancreatic cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.3;HSkMC: 45.9;hTERT-RPE1: 46.5;SCLC-21H: 47.6;SH-SY5Y: 20.7;WM-115: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 330000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Vesicles "HPA011893: AB_1856656, HPA075062: AB_2732277" "unprognostic (2.93e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-3)" "unprognostic (6.82e-4)" "unprognostic (2.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-3)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "prognostic favorable (5.58e-4)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.01e-10)" "unprognostic (2.47e-3)" "unprognostic (4.02e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-3)" 9.2 360.1 49.2 30.2 78.4 0.4 0.5 17.1 54.7 1.5 2.2 10.6 47.7 3.5 0.4 0.6 0.2 4.0 1.7 21.7 426.2 0.6 0.2 3.3 0.4 118.3 195.4 6.1 28.3 0.5 269.0 1.1 250.9 3.5 13.0 40.6 0.3 1.2 0.3 1.0 21.3 12.8 77.4 0.2 17.9 0.2 130.7 0.1 6.4 0.8 0.1 0.8 1.3 30.3 0.0 3.1 10.3 8.5 2.3 53.3 0.2 0.5 2.0 4.0 10.1 0.4 1.0 0.0 0.9 0.7 6.2 0.2 0.2 0.0 5.0 0.1 0.5 0.0 0.6 0.0 0.5 0.7 4.6 45.9 0.2 5.8 2.0 46.5 0.0 0.0 0.2 0.4 5.1 0.3 0.0 0.2 7.3 0.1 0.2 0.0 0.3 0.3 0.9 0.1 47.6 20.7 0.0 0.5 2.5 1.6 0.0 0.1 0.1 5.4 2.2 0.2 3.6 0.1 0.0 0.3 1.6 0.1 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 78.4 17.1 54.7 21.7 426.2 118.3 195.4 250.9 77.4 130.7 30.3 0.0 6.4 0.0 12.7 0.0 0.0 0.4 2.8 0.0 212.4 0.0 0.0 0.1 0.0 1.3 0.0 2.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.2 6.7 283.4 0.0 27.7 0.2 0.0 2.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 8.4 109.9 14.7 138.4 0.3 0.3 0.0 0.6 0.0 1.8 3.7 0.0 11.6 0.0 34.2 8.2 14.8 6.2 0.4 0.0 2.1 0.1 0.1 0.7 14.6 0.0 1.8 1.7 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.5 0.8 SCG3 "FLJ90833, SgIII" ENSG00000104112 "Secretogranin III" Q8WXD2 15 51681492-51721026 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 133.5;choroid plexus: 40.1;pituitary gland: 39.4;retina: 56.8" "Group enriched" "Detected in many" 4 "Astrocytes: 79.3;Bipolar cells: 120.4;Cone photoreceptor cells: 102.2;Enteroendocrine cells: 148.4;Excitatory neurons: 46.2;Horizontal cells: 148.0;Inhibitory neurons: 64.0;Ionocytes: 38.7;Oligodendrocyte precursor cells: 63.3;Rod photoreceptor cells: 93.3" "Group enriched" "Detected in many" 7 "glioma: 41.0;pancreatic cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 50.5;SCLC-21H: 121.2;SH-SY5Y: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006880, CAB033274, HPA053715" Enhanced Supported Supported Vesicles "Secreted in brain" NA NA 3100000 "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Vesicles "CAB033274: AB_2302033, HPA006880: AB_1079898, HPA053715: AB_2682239" "unprognostic (1.38e-2)" "unprognostic (2.42e-1)" "unprognostic (1.40e-1)" "unprognostic (5.24e-5)" "unprognostic (1.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.74e-1)" "unprognostic (9.93e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (8.17e-2)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" 0.5 16.7 71.0 1.1 87.0 0.6 0.5 85.8 133.5 0.1 40.1 1.8 2.3 0.2 0.3 0.3 0.3 0.2 0.2 88.2 112.7 0.2 0.2 0.6 0.4 68.7 75.8 0.1 15.6 0.2 39.4 0.1 68.9 0.3 2.0 56.8 0.2 0.0 0.1 0.6 2.0 0.5 71.9 0.2 9.9 2.6 79.8 0.5 1.0 0.0 0.2 0.2 0.2 71.6 0.2 0.1 4.8 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.2 0.3 0.5 0.0 0.6 0.4 0.1 0.0 0.1 0.1 0.5 0.1 0.3 0.1 0.0 0.3 3.0 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.8 0.0 0.3 0.1 0.1 50.5 0.1 0.2 0.3 0.1 0.4 0.0 0.5 121.2 57.5 0.2 0.4 0.2 15.5 0.1 3.8 0.1 0.3 0.7 0.2 0.2 0.4 0.2 0.4 0.7 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 71.0 87.0 85.8 133.5 88.2 112.7 68.7 75.8 68.9 71.9 79.8 71.6 0.2 0.0 0.0 79.3 0.0 0.3 0.0 0.3 0.0 120.4 0.0 0.1 0.2 0.0 0.1 0.0 102.2 0.0 0.0 0.2 1.9 0.4 20.0 0.0 0.0 4.3 148.4 0.0 46.2 1.0 0.1 4.1 0.0 0.0 0.0 0.0 1.8 0.0 0.4 148.0 64.0 3.4 38.7 0.0 0.3 11.3 0.0 0.1 1.8 7.5 6.7 19.2 0.0 63.3 8.9 5.3 0.0 0.4 0.0 0.4 0.1 0.0 0.8 93.3 0.0 0.4 0.2 13.8 5.8 0.0 0.0 0.0 0.0 0.2 0.3 0.3 SCG5 "7B2, SGNE1, SgV" ENSG00000166922 "Secretogranin V" P05408 15 32641676-32697098 "Predicted secreted proteins" Transport "Chaperone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.0;pituitary gland: 402.7" "Cell type enriched" "Detected in many" 4 "Enteroendocrine cells: 470.8" "Group enriched" "Detected in many" 5 "glioma: 38.2;pancreatic cancer: 82.9;thyroid cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 26.9;HSkMC: 33.5;NTERA-2: 15.3;SCLC-21H: 31.5;SH-SY5Y: 36.4;U-87 MG: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013136, HPA074618" Enhanced "Secreted to blood" NA NA 100000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA013136: AB_1856657, HPA074618: AB_2732262" "unprognostic (1.71e-1)" "unprognostic (9.87e-2)" "unprognostic (7.94e-2)" "unprognostic (1.30e-2)" "unprognostic (3.59e-3)" "prognostic unfavorable (9.64e-4)" "unprognostic (2.69e-1)" "unprognostic (1.27e-3)" "unprognostic (4.69e-2)" "unprognostic (1.97e-1)" "unprognostic (5.62e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (4.51e-9)" "unprognostic (3.57e-2)" "unprognostic (8.13e-2)" "unprognostic (3.08e-3)" "unprognostic (8.88e-2)" 1.7 61.1 54.0 3.3 62.0 0.3 3.7 52.2 100.4 1.0 77.3 7.9 17.9 5.3 42.5 0.5 3.4 5.5 1.3 58.9 75.1 0.9 3.6 3.8 1.3 56.5 48.3 3.2 133.0 73.7 402.7 0.3 58.7 5.0 9.8 26.7 0.2 0.9 0.2 1.3 5.6 6.7 57.7 0.5 37.8 5.3 56.3 0.3 5.8 0.1 0.3 2.6 2.7 58.9 0.5 0.2 0.1 0.2 0.6 4.5 0.1 4.2 0.4 0.4 0.4 0.1 0.0 0.5 1.9 0.4 1.7 1.2 0.5 0.2 1.2 0.7 0.3 0.6 0.0 0.1 26.9 0.2 0.7 33.5 0.1 0.8 0.4 0.9 0.7 1.0 0.3 0.6 0.8 0.0 0.3 0.3 15.3 0.1 0.8 0.1 0.4 0.6 0.4 0.0 31.5 36.4 0.2 0.0 0.2 0.4 0.1 0.4 0.0 5.2 3.8 0.3 0.5 0.6 2.3 0.4 47.2 1.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.0 62.0 52.2 100.4 58.9 75.1 56.5 48.3 58.7 57.7 56.3 58.9 0.2 0.0 0.5 20.2 0.3 0.6 0.2 6.2 0.0 51.0 0.5 16.5 0.4 0.0 3.9 0.0 2.1 0.2 0.1 1.1 0.0 0.6 52.1 3.7 19.3 1.1 470.8 0.0 82.8 78.3 0.3 17.9 23.0 0.6 2.5 51.4 0.4 11.9 6.0 50.5 97.8 14.5 97.6 0.6 0.8 80.0 2.1 1.6 3.6 20.6 0.6 15.6 0.0 52.3 79.7 22.9 1.1 7.9 0.3 1.4 0.5 0.0 0.5 32.6 0.0 0.3 34.2 39.2 2.9 0.1 0.3 0.3 0.3 51.8 2.4 1.0 SCGB1A1 "CC10, CC16, CCSP, UGB" ENSG00000149021 "Secretoglobin family 1A member 1" P11684 11 62405103-62423195 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Phospholipase A2 inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lung: 3079.0" "Cell type enriched" "Detected in some" 4 "Club cells: 43564.7" "Cancer enriched" "Detected in many" 8 "lung cancer: 215.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 71 "HaCaT: 1977.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025686, HPA031828" Enhanced "Secreted in other tissues" NA NA 13000000 "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025686: , HPA031828: AB_2674061" "unprognostic (2.40e-3)" "unprognostic (1.55e-2)" "unprognostic (5.46e-2)" "unprognostic (2.70e-2)" "unprognostic (4.69e-3)" "unprognostic (2.12e-2)" "unprognostic (1.23e-2)" "unprognostic (2.31e-2)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" 1.1 2.0 0.6 0.9 0.7 0.1 0.3 1.3 1.1 0.6 0.3 0.2 0.4 0.2 0.7 11.0 334.2 0.2 0.6 0.5 0.6 0.2 0.4 3079.0 0.2 0.6 0.9 2.0 1.9 0.0 2.4 1.7 0.5 85.1 0.0 0.2 0.5 0.9 0.3 0.3 1.6 0.0 0.5 7.2 4.3 0.2 1.0 2.8 0.4 0.0 5.9 0.2 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 1977.1 0.0 0.3 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.3 27.9 0.0 0.0 0.0 0.0 0.1 0.2 0.8 0.0 1.1 0.0 0.0 0.6 1.4 0.4 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.1 0.4 0.0 0.0 1.0 2.0 0.0 1.0 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.3 1.1 0.5 0.6 0.6 0.9 0.5 0.5 1.0 0.5 0.0 1125.0 2573.3 0.0 0.0 0.0 71.4 3938.5 0.0 0.0 0.0 0.0 0.0 0.0 43564.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 113.5 0.0 0.0 0.1 0.0 0.0 304.5 0.0 0.5 691.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4534.8 0.0 0.0 0.7 0.0 128.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.0 0.0 134.7 0.0 0.0 9997.0 0.0 0.0 0.0 850.3 0.0 0.0 3.9 0.0 0.0 83.7 0.0 0.0 800.2 SCGB1C1 RYD5 ENSG00000188076 "Secretoglobin family 1C member 1" Q8TD33 11 193078-194575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;pancreas: 1.4;retina: 3.4;salivary gland: 1.0" "Cell type enriched" "Detected in single" 5 "Macrophages: 2.7" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Region enhanced" "Detected in single" "pons: 1.3" "Group enriched" "Detected in some" 32 "basophil: 5.0;neutrophil: 1.3" "Lineage enriched" "Detected in single" 50 "granulocytes: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (5.09e-3)" 0.0 0.1 0.1 0.1 0.1 0.7 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 1.3 0.0 0.0 3.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.1 0.1 0.7 0.3 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCGB1C2 ENSG00000268320 "Secretoglobin family 1C member 2" P0DMR2 17 137569-139067 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 1.5;retina: 1.0" "Cell type enriched" "Detected in some" 4 "Muller glia cells: 5.0" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (4.65e-2)" 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.9 0.0 0.0 0.1 5.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCGB1D1 "LIPA, LPHA, MGC71958" ENSG00000168515 "Secretoglobin family 1D member 1" O95968 11 62190216-62193539 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "endometrial cancer: 23.3;ovarian cancer: 16.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "SCLC-21H: 6.0" "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "unprognostic (6.95e-3)" "unprognostic (9.01e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1227.2;cervix: 4002.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3242.1;Glandular and luminal cells: 3417.9" "Group enriched" "Detected in many" 6 "breast cancer: 625.1;endometrial cancer: 226.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 10.4" HPA035318 Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "HPA035318: AB_10610421" "unprognostic (8.76e-2)" "unprognostic (2.14e-1)" "prognostic favorable (3.46e-6)" "unprognostic (2.39e-2)" "unprognostic (5.89e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "prognostic favorable (8.03e-6)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" 12.9 4.9 4.1 0.0 4.0 0.0 1227.2 3.2 5.4 4002.8 13.8 0.3 0.1 89.0 355.8 10.1 110.3 0.1 3.1 3.5 4.4 10.1 0.2 0.1 0.1 4.7 5.7 1.1 4.5 0.5 5.2 0.2 4.2 8.6 0.2 1.8 69.2 2.9 7.2 342.4 0.4 0.0 3.5 0.0 0.3 0.2 4.3 0.4 0.6 6.0 0.0 0.2 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.1 0.0 1.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.0 3.2 5.4 3.5 4.4 4.7 5.7 4.2 3.5 4.3 4.6 2.1 0.0 0.0 0.0 1.6 27.4 4.8 0.0 0.0 0.5 647.8 251.6 10.9 0.0 0.0 7.3 0.0 0.0 5.3 0.0 23.5 0.3 0.0 3242.1 409.9 12.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 3417.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 15.0 823.6 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 46.1 0.0 0.9 0.0 0.2 8.6 0.0 0.0 0.0 7.0 0.1 20.0 0.0 0.0 1.1 SCGB1D4 IIS ENSG00000197745 "Secretoglobin family 1D member 4" Q6XE38 11 62296281-62299075 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "cervix: 52.3;endometrium 1: 15.6;epididymis: 43.7;fallopian tube: 53.7" "Cell type enriched" "Detected in some" 6 "Endometrial ciliated cells: 3089.4" "Cancer enriched" "Detected in some" 57 "endometrial cancer: 100.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.26e-3)" "unprognostic (3.20e-1)" 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 52.3 0.0 0.0 0.0 15.6 43.7 0.0 53.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 3089.4 111.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 457.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.9 0.0 0.0 0.0 SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 2021.0;epididymis: 1372.0" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2506.4;Glandular and luminal cells: 2597.0" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 8.6" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" 0.2 0.0 0.0 0.2 0.0 0.0 57.8 0.0 0.0 2021.0 0.1 12.7 1.3 118.8 1372.0 4.2 238.4 13.4 0.2 0.1 0.4 1.9 0.1 2.4 0.0 3.5 1.4 0.7 17.2 1.1 5.1 0.1 0.8 6.8 16.3 0.0 29.6 15.6 0.0 8.6 1.0 2.2 0.5 0.0 45.9 0.0 1.1 2.7 5.8 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 1.6 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.5 1.4 0.8 0.5 1.1 0.2 0.6 0.0 4.8 0.0 0.4 0.1 3.8 4.8 0.0 0.0 123.6 71.0 0.0 48.6 10.1 16.5 0.0 0.2 1.6 9.7 3.9 6.6 0.0 2506.4 397.7 7.6 37.1 0.0 0.0 5.3 0.0 3.8 26.5 2597.0 0.0 0.3 0.0 0.1 4.9 0.0 0.0 59.9 10.2 0.3 0.0 0.0 0.0 14.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 15.3 10.8 0.0 0.0 27.0 0.7 0.1 109.3 0.0 0.0 0.0 8.5 0.0 0.0 1.7 0.4 0.0 13.7 0.1 7.0 16.6 SCGB2A2 "MGB1, MGC71974, PSBP1, UGB2" ENSG00000110484 "Secretoglobin family 2A member 2" Q13296 11 62270158-62273160 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "breast: 2805.9;skin 1: 708.1" "Group enriched" "Detected in some" 11 "Breast glandular cells: 2119.6;Breast myoepithelial cells: 1028.8;Melanocytes: 1762.7" "Cancer enriched" "Detected in many" 23 "breast cancer: 823.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 124 "SK-BR-3: 18.0" CAB026270 Enhanced "Secreted in female reproductive system" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "CAB026270: AB_912980" "unprognostic (2.38e-1)" "unprognostic (7.28e-2)" "prognostic favorable (9.57e-8)" "unprognostic (4.17e-1)" "unprognostic (3.75e-1)" 34.4 0.2 0.0 0.0 0.0 0.0 2805.9 0.0 0.0 309.2 0.0 0.4 0.0 4.1 0.0 76.6 0.1 0.0 4.0 0.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 1.6 1.3 0.0 0.2 0.0 0.0 159.3 0.1 1.8 708.1 0.2 0.0 0.0 0.2 0.3 1.1 0.0 2.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.6 49.6 0.3 0.0 0.0 0.0 2119.6 1028.8 0.1 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 1.4 41.9 21.6 11.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 141.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 3.2 1762.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 10.9 0.0 9.2 0.0 0.0 0.0 SCGB2B2 "SCGB4A2, SCGBL" ENSG00000205209 "Secretoglobin family 2B member 2" Q4G0G5 19 34593329-34675699 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 8.6" "Cell type enhanced" "Detected in some" "Astrocytes: 63.6;Excitatory neurons: 32.8;Inhibitory neurons: 45.3;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8;Oligodendrocytes: 104.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;U-266/70: 1.0" HPA046806 Uncertain "Secreted in other tissues" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA046806: AB_10962373" "unprognostic (9.99e-2)" "unprognostic (3.62e-1)" "unprognostic (9.51e-2)" "unprognostic (1.38e-5)" "unprognostic (4.80e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-2)" "unprognostic (2.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-3)" "unprognostic (3.67e-1)" "unprognostic (3.52e-2)" "unprognostic (2.90e-1)" "unprognostic (2.49e-1)" "unprognostic (3.40e-2)" "unprognostic (1.52e-1)" 0.3 0.4 0.7 0.0 1.0 0.1 0.9 0.4 0.9 0.1 0.1 0.2 0.1 0.3 2.6 0.9 0.3 0.2 0.3 0.6 0.7 0.3 0.5 0.5 0.3 1.0 1.0 0.2 8.6 0.3 0.3 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.7 2.9 0.2 0.1 0.5 0.4 0.3 2.0 1.0 0.1 0.5 1.1 0.3 0.4 0.1 0.9 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.2 0.4 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.4 0.2 0.4 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.4 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 1.0 0.4 0.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.4 0.9 0.6 0.7 1.0 1.0 0.9 0.5 1.0 0.9 0.0 0.0 0.0 63.6 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.1 0.0 0.2 0.0 0.0 32.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.3 0.0 0.0 0.0 0.0 31.0 0.0 0.0 3.6 17.8 0.0 0.0 0.0 52.8 104.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 270.0;lung: 508.1;salivary gland: 746.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2883.9;Breast myoepithelial cells: 4199.8;Club cells: 13674.8;Respiratory ciliated cells: 3325.6;Urothelial cells: 3139.7" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 51.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NB-4: 2.3;T-47d: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" 1.8 1.5 1.1 0.2 1.2 0.5 122.4 0.7 1.2 270.0 11.7 0.5 0.6 1.5 1.2 74.8 29.9 2.9 0.7 1.1 5.9 1.5 7.0 508.1 0.4 1.4 1.6 2.0 18.2 0.0 12.6 0.1 1.0 37.9 0.0 0.0 746.5 2.4 0.3 4.9 1.0 0.0 1.2 9.4 50.7 3.0 3.0 0.8 3.1 0.0 0.8 14.5 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 20.3 2.4 17.2 13.3 1.8 3.3 4.5 10.1 0.0 5.9 5.0 0.0 0.0 51.8 0.2 4.3 2.6 1.1 1.2 0.7 1.2 1.1 5.9 1.4 1.6 1.0 1.2 3.0 1.5 36.4 173.1 1441.5 0.0 5.9 0.5 51.2 2883.9 0.6 0.0 1831.7 4199.8 0.4 1554.2 13674.8 0.0 0.0 0.0 30.4 0.1 0.0 20.5 0.1 1.6 0.1 40.5 0.0 10.7 0.2 1.6 0.3 15.2 3.6 1.7 35.3 1.0 68.9 1.1 0.4 0.0 0.0 0.1 1566.5 1.2 0.6 0.2 0.6 14.8 5.4 0.0 0.6 0.0 0.0 0.0 0.1 146.1 0.5 0.0 0.0 214.9 0.0 0.0 3325.6 0.0 0.0 1.6 305.2 0.3 4.4 140.8 0.4 0.0 20.2 0.1 0.2 3139.7 SCGB3A2 "LU103, PNSP1, UGRP1" ENSG00000164265 "Secretoglobin family 3A member 2" Q96PL1 5 147870682-147882191 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 124 "lung: 1271.2" "Group enriched" "Detected in some" 8 "Alveolar cells type 2: 4396.4;Club cells: 6565.6" "Cancer enriched" "Detected in some" 10 "lung cancer: 211.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 50 "basophil: 71.6" "Lineage enriched" "Detected in many" 50 "granulocytes: 71.6" "Cell line enhanced" "Detected in many" "A-431: 89.1;EFO-21: 52.3;NTERA-2: 61.0;PC-3: 302.9;SuSa: 120.6" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 800000 "Cluster 46: Basophils - DNA binding" "Cluster 19: Lung - Lung function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.85e-1)" "unprognostic (1.77e-1)" "unprognostic (2.99e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-2)" "unprognostic (3.17e-2)" "unprognostic (1.05e-2)" "unprognostic (1.90e-8)" "unprognostic (9.31e-3)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (9.11e-2)" 0.6 0.6 3.3 1.5 2.4 2.4 4.0 5.3 6.0 0.7 0.6 0.6 1.0 1.7 5.0 2.1 1.4 1.2 1.7 3.3 6.2 1.2 1.3 1271.2 2.8 3.4 1.2 2.1 0.6 0.7 1.1 2.0 3.1 1.1 1.8 10.2 6.2 1.4 2.1 5.0 1.4 0.9 0.3 4.2 4.1 1.9 2.0 1.3 7.2 0.8 2.2 0.7 0.1 2.6 89.1 1.3 1.1 2.0 1.1 0.6 2.3 1.4 0.3 0.2 0.2 0.5 1.1 0.4 52.3 0.3 0.8 0.8 2.5 1.3 0.5 0.3 1.6 3.4 10.5 0.3 0.0 0.7 3.3 1.4 0.8 0.7 0.0 2.0 0.2 0.3 2.4 1.1 0.2 1.7 0.9 0.8 61.0 0.0 302.9 0.2 0.9 0.3 1.2 0.7 4.3 1.1 12.3 1.1 0.2 120.6 1.3 0.6 1.7 1.2 35.5 1.6 1.3 1.7 1.4 0.4 0.4 1.5 4.1 71.6 1.0 0.2 0.4 0.7 0.1 0.2 0.2 0.2 0.6 0.4 0.0 0.2 0.4 1.4 0.9 0.3 0.2 0.1 3.3 2.4 5.3 6.0 3.3 6.2 3.4 1.2 3.1 0.3 2.0 2.6 0.0 618.6 4396.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 6565.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 14.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.2 106.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 623.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.2 SCN1B ENSG00000105711 "Sodium voltage-gated channel beta subunit 1" Q07699 19 35030470-35040449 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 256.5;skeletal muscle: 572.0;tongue: 227.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.9;Excitatory neurons: 50.4;Hofbauer cells: 31.3;Inhibitory neurons: 48.3;Kupffer cells: 35.1;Macrophages: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.5;EFO-21: 12.7;TIME: 26.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 349.1" "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (8.18e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (6.40e-2)" "unprognostic (1.17e-2)" "unprognostic (2.69e-2)" "unprognostic (4.40e-2)" "unprognostic (1.20e-1)" "unprognostic (3.34e-2)" "unprognostic (4.72e-3)" "prognostic favorable (1.38e-4)" "unprognostic (2.25e-1)" "unprognostic (2.05e-2)" "unprognostic (9.68e-3)" "unprognostic (5.81e-2)" "unprognostic (4.12e-2)" "unprognostic (4.78e-2)" 20.2 13.6 48.2 3.3 53.0 2.3 16.3 95.8 256.5 15.5 7.7 9.7 1.9 9.4 2.2 8.6 21.7 4.8 95.4 45.0 97.2 8.3 8.5 11.1 3.0 120.4 67.0 7.8 12.3 18.2 17.4 5.3 115.7 8.7 2.7 10.7 15.4 3.6 572.0 6.3 8.0 4.5 52.2 19.8 8.4 2.8 153.5 1.3 11.1 227.8 0.8 13.4 10.5 113.6 0.4 17.5 0.2 1.0 5.2 7.8 0.1 7.1 6.1 3.4 0.9 0.7 0.2 0.2 12.7 7.1 3.0 0.3 1.1 0.7 1.6 0.2 0.8 0.2 2.5 4.5 6.9 0.1 0.1 2.5 0.1 0.4 0.2 6.8 11.6 0.2 0.4 0.1 2.2 1.7 0.2 0.2 0.8 1.6 5.1 0.9 1.8 0.2 0.5 0.1 8.1 4.3 0.9 0.1 1.4 0.6 1.6 0.4 26.1 6.7 6.6 0.3 4.6 0.3 0.5 1.0 4.0 0.8 4.8 0.7 0.2 0.1 0.3 0.1 0.6 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.3 0.7 48.2 53.0 95.8 256.5 45.0 97.2 120.4 67.0 115.7 52.2 153.5 113.6 12.8 0.0 3.3 11.8 1.1 1.8 0.8 1.6 0.0 67.9 1.6 7.7 20.3 0.0 0.6 0.0 2.1 0.4 2.9 0.0 9.8 0.3 0.3 2.0 2.0 9.7 0.0 0.4 50.4 2.6 0.6 9.9 2.0 1.8 2.5 0.1 20.7 1.2 31.3 8.4 48.3 1.6 0.0 35.1 3.7 0.0 7.5 29.5 3.6 15.9 3.0 13.3 0.0 6.0 18.5 0.7 0.1 2.2 2.7 1.1 0.1 2.5 1.0 22.8 0.0 25.3 3.6 0.2 0.7 0.1 1.1 1.0 2.0 0.1 0.8 0.3 SCPEP1 RISC ENSG00000121064 "Serine carboxypeptidase 1" Q9HB40 17 56978129-57006768 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 300.9" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 456.2;Club cells: 304.9;Respiratory ciliated cells: 397.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 319.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 389.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039102, HPA057200" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA039102: AB_10673605, HPA057200: AB_2683365" "unprognostic (5.83e-3)" "unprognostic (7.43e-3)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (9.26e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "unprognostic (1.70e-1)" "unprognostic (3.56e-3)" "unprognostic (1.40e-1)" "unprognostic (3.25e-1)" "unprognostic (7.28e-2)" "unprognostic (8.89e-2)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" 64.1 121.5 25.7 32.6 26.4 75.8 91.0 27.3 42.9 69.8 34.5 46.9 31.4 37.5 73.1 54.8 48.5 71.2 60.1 27.2 30.9 88.6 32.0 95.1 48.7 30.1 29.5 53.6 17.0 300.9 28.7 20.8 30.6 61.6 33.7 8.1 90.0 102.9 15.8 46.3 40.3 60.9 28.7 44.8 54.2 14.3 28.4 14.6 135.1 32.5 60.6 71.1 51.1 33.6 48.3 20.9 49.4 41.4 389.3 85.6 26.0 23.3 119.6 41.9 77.8 13.7 33.3 63.3 126.4 55.9 65.8 44.0 22.0 105.4 46.8 82.0 36.1 19.8 28.2 8.7 89.1 39.1 190.1 103.7 45.0 52.0 43.0 37.5 72.3 24.3 5.1 257.9 59.1 20.3 19.9 100.4 20.4 15.2 39.3 24.2 53.8 41.4 9.3 143.7 13.8 33.8 56.3 45.6 33.3 57.1 19.1 104.1 34.1 118.3 29.9 68.8 26.5 250.5 187.2 35.9 88.1 28.5 34.4 2.1 228.5 319.0 11.8 137.1 8.0 56.0 8.2 8.3 105.7 55.1 11.3 12.3 34.8 23.7 141.0 18.0 10.2 118.7 25.7 26.4 27.3 42.9 27.2 30.9 30.1 29.5 30.6 28.7 28.4 33.6 48.8 44.8 61.8 25.1 52.7 23.7 208.6 456.2 37.5 12.7 52.4 110.7 32.5 10.0 304.9 95.6 16.7 9.9 20.5 2.0 19.6 22.2 1.0 51.5 24.5 27.1 24.4 21.2 37.2 6.8 19.4 115.4 4.6 13.6 8.2 4.3 62.8 15.7 160.5 10.1 24.9 5.0 126.1 135.0 33.7 3.4 64.3 110.2 24.9 20.6 142.2 18.9 25.7 21.1 20.7 4.8 1.6 68.1 39.0 74.1 62.4 29.7 397.8 17.0 52.6 28.1 63.2 4.4 12.3 38.1 19.9 11.1 18.8 67.1 8.0 122.6 SCRG1 SCRG-1 ENSG00000164106 "Stimulator of chondrogenesis 1" O75711 4 173384701-173406380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7;choroid plexus: 15.2" "Cell type enhanced" "Detected in many" "Astrocytes: 46.4;Muller glia cells: 148.3;Oligodendrocyte precursor cells: 102.1" "Cancer enriched" "Detected in many" 6 "glioma: 35.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "WM-115: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012882 Approved "Secreted in brain" NA NA 240000 "Cluster 17: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA012882: AB_1856635" "unprognostic (1.09e-1)" "unprognostic (1.83e-2)" "unprognostic (2.60e-5)" "unprognostic (2.58e-1)" "unprognostic (3.22e-2)" "unprognostic (7.51e-2)" "unprognostic (3.58e-2)" "unprognostic (1.14e-3)" "unprognostic (2.08e-1)" "unprognostic (2.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.95e-10)" "unprognostic (4.86e-2)" "unprognostic (2.21e-1)" "unprognostic (4.34e-3)" "unprognostic (8.74e-4)" 1.3 0.8 19.0 0.6 20.5 0.7 0.5 20.6 30.7 1.6 15.2 4.4 0.5 1.8 0.9 0.4 2.5 1.5 2.9 19.4 20.3 0.2 0.1 0.4 0.2 22.8 19.9 0.8 0.3 0.0 1.0 0.2 22.5 2.3 0.5 2.3 1.1 3.2 0.5 0.5 0.9 4.7 21.6 0.5 2.8 10.8 19.4 0.0 0.3 0.0 0.1 2.0 0.8 24.7 0.1 0.0 0.6 0.2 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.5 0.2 0.1 3.5 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 17.1 1.8 0.5 0.3 0.2 0.4 0.1 0.2 0.1 0.2 0.2 0.3 0.2 0.3 1.2 0.5 0.5 0.3 0.1 0.1 19.0 20.5 20.6 30.7 19.4 20.3 22.8 19.9 22.5 21.6 19.4 24.7 1.3 0.0 3.0 46.4 1.0 3.6 1.1 0.0 0.0 14.5 2.4 3.9 1.3 0.0 0.7 0.0 37.5 0.2 3.3 0.3 0.0 0.3 18.3 0.7 1.7 2.1 1.2 0.0 19.0 0.0 0.4 17.3 1.1 0.4 8.9 0.9 4.2 0.3 0.6 16.8 20.9 0.5 0.0 3.3 2.6 32.3 26.1 3.8 23.2 2.8 1.9 148.3 2.1 102.1 26.4 0.2 0.1 20.7 1.0 1.9 0.4 0.3 0.8 28.3 13.1 2.4 20.3 3.1 2.4 0.1 2.6 0.7 3.1 0.5 0.3 1.0 SCT ENSG00000070031 Secretin P09683 11 626309-627181 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 44.2" "Cell type enhanced" "Detected in some" "dendritic cells: 92.8;Enteroendocrine cells: 267.8;Intestinal goblet cells: 46.4;Proximal enterocytes: 39.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 138 "plasmacytoid DC: 126.7" "Lineage enriched" "Detected in single" 138 "dendritic cells: 126.7" "Cell line enhanced" "Detected in single" "HSkMC: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050961 Enhanced "Secreted to blood" NA NA 571000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA050961: AB_2681291" "unprognostic (5.28e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (3.70e-4)" "unprognostic (2.72e-1)" "unprognostic (7.91e-2)" "unprognostic (1.73e-1)" "unprognostic (2.43e-3)" "unprognostic (4.19e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-2)" "unprognostic (1.88e-1)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (8.37e-2)" "unprognostic (5.45e-1)" "unprognostic (6.09e-2)" "unprognostic (1.13e-1)" 0.1 0.2 0.7 0.1 1.8 0.6 0.0 1.9 1.9 0.3 0.0 0.9 44.2 0.1 0.3 0.3 0.2 0.0 1.8 0.7 0.3 0.4 0.4 2.2 1.3 1.3 0.7 0.4 0.2 0.0 2.0 0.7 1.5 0.6 0.1 0.2 0.2 0.0 10.3 0.1 8.6 0.0 0.1 3.3 0.7 3.0 1.4 0.4 0.5 1.3 0.7 0.3 0.1 4.1 0.1 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.9 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.9 0.0 126.7 0.0 0.4 0.7 1.8 1.9 1.9 0.7 0.3 1.3 0.7 1.5 0.1 1.4 4.1 0.1 0.0 0.0 0.7 4.1 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.4 1.5 0.0 0.0 0.0 0.1 92.8 1.6 1.9 0.0 1.7 0.3 0.3 0.1 267.8 0.0 0.0 0.0 0.0 1.9 1.1 0.4 0.0 3.5 0.4 0.0 0.2 0.0 0.1 46.4 0.0 0.0 1.2 1.1 1.5 3.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 13.6 0.0 0.0 0.2 39.2 0.2 0.0 0.0 0.0 1.6 0.2 0.8 10.2 0.0 0.1 0.0 0.1 0.1 3.2 0.2 SCUBE1 ENSG00000159307 "Signal peptide, CUB domain and EGF like domain containing 1" Q8IWY4 22 43197280-43343372 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 26.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 13.3;Granulosa cells: 37.2;Peritubular cells: 45.5;Theca cells: 14.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 49.8;THP-1: 20.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003190 Approved "Secreted to blood" NA NA 2170000 190000 "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA003190: AB_1079882" "unprognostic (5.29e-2)" "unprognostic (7.15e-6)" "unprognostic (6.03e-3)" "unprognostic (8.33e-2)" "unprognostic (3.65e-1)" "unprognostic (4.55e-2)" "unprognostic (1.34e-1)" "unprognostic (5.76e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-2)" "unprognostic (1.02e-2)" "unprognostic (2.70e-1)" "unprognostic (2.30e-1)" "unprognostic (6.87e-3)" 1.8 6.1 0.8 0.8 1.1 0.1 1.2 0.1 1.4 0.9 4.1 3.8 5.9 1.1 0.1 3.6 1.2 0.8 0.2 0.6 3.8 3.5 5.1 6.8 0.0 1.7 10.2 26.4 0.1 9.1 3.8 2.6 7.0 1.9 2.0 0.4 3.6 0.5 9.6 0.6 7.7 0.5 0.3 5.7 7.0 7.1 1.2 0.1 3.1 1.9 0.0 3.3 0.7 0.4 0.0 0.0 2.2 7.8 0.0 0.0 4.9 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.1 0.1 0.3 0.1 0.7 0.0 0.0 0.1 0.7 0.0 0.1 0.7 0.2 0.2 49.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.2 0.0 0.1 0.0 0.3 0.1 20.4 0.0 0.3 0.2 0.6 0.0 2.1 4.3 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.1 1.4 0.6 3.8 1.7 10.2 7.0 0.3 1.2 0.4 0.2 9.6 1.7 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.9 0.1 1.4 0.0 0.6 0.0 0.0 0.2 0.2 0.0 1.9 0.1 3.0 1.3 1.2 1.3 0.0 0.0 0.4 0.0 13.3 2.6 0.5 3.4 1.3 37.2 0.4 1.9 0.8 0.0 0.3 0.2 0.0 0.0 0.4 4.6 7.8 0.2 0.0 0.0 0.1 4.1 0.0 0.0 0.3 0.1 0.0 45.5 0.4 0.0 0.0 0.4 0.7 0.2 0.0 0.4 1.2 3.8 2.0 0.0 0.1 0.4 2.8 14.3 0.0 0.1 SCUBE2 "Cegb1, Cegf1, FLJ16792" ENSG00000175356 "Signal peptide, CUB domain and EGF like domain containing 2" Q9NQ36 11 9019476-9138114 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 48.8" "Cell type enhanced" "Detected in many" "Adipocytes: 30.3;Basal prostatic cells: 51.4;Breast glandular cells: 45.0;Breast myoepithelial cells: 31.5;Prostatic glandular cells: 39.8" "Cancer enhanced" "Detected in all" "breast cancer: 54.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 6 "monocytes: 1.0" "Cell line enhanced" "Detected in some" "HAP1: 5.7;SK-MEL-30: 8.1;T-47d: 28.4" "Group enriched" "Detected in some" 4 "olfactory bulb: 4.6;thalamus: 2.7" "Low region specificity" "Detected in all" "HPA006353, HPA029871" Uncertain "Secreted to blood" NA NA 1100000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "HPA006353: AB_1856642, HPA029871: AB_10602299" "prognostic favorable (2.41e-4)" "unprognostic (5.72e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "unprognostic (2.73e-1)" "unprognostic (6.12e-4)" "unprognostic (3.11e-1)" "unprognostic (6.39e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (1.54e-2)" "unprognostic (3.04e-1)" "unprognostic (1.94e-2)" "unprognostic (9.12e-4)" "unprognostic (4.35e-1)" "unprognostic (5.94e-2)" "unprognostic (2.88e-1)" 14.8 2.0 3.5 3.7 3.5 0.0 32.2 13.7 3.1 17.6 0.2 11.1 3.6 13.4 48.8 4.5 18.2 7.9 4.3 4.0 4.9 1.3 0.9 4.6 3.9 3.0 3.6 0.9 22.0 19.5 9.6 22.5 3.7 33.3 4.5 1.9 2.3 8.7 9.0 12.3 16.3 13.0 5.4 5.0 21.4 2.2 4.7 2.4 5.2 6.2 7.6 28.6 6.9 5.1 0.0 0.1 1.5 0.9 0.5 0.6 0.2 1.6 0.8 0.9 0.6 0.3 0.0 0.0 0.6 3.9 0.1 0.0 5.7 0.0 1.4 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.1 1.3 0.0 0.4 0.0 0.3 0.6 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.9 0.0 0.0 0.1 0.0 0.2 0.4 3.1 0.7 1.0 1.1 0.1 8.1 1.3 28.4 0.0 0.0 0.6 0.4 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.5 3.5 13.7 3.1 4.0 4.9 3.0 3.6 3.7 5.4 4.7 5.1 30.3 16.0 9.2 1.6 0.0 7.4 51.4 0.3 1.2 0.4 45.0 31.5 0.6 0.0 5.6 1.8 0.0 0.2 0.1 1.0 0.0 0.1 3.4 2.2 8.8 3.3 1.2 0.0 3.1 1.8 0.2 9.4 0.0 6.4 0.0 0.3 1.1 0.1 0.8 13.5 14.9 5.2 6.1 0.3 1.5 2.5 0.3 0.7 19.6 5.6 0.1 0.0 0.0 13.6 4.6 0.1 4.3 0.7 0.0 39.8 0.6 0.0 1.5 0.3 0.0 5.2 1.5 0.6 0.7 0.1 1.8 0.4 0.3 6.6 9.6 15.6 SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 10.8;Horizontal cells: 10.1;Rod photoreceptor cells: 7.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.0;ASC diff: 76.7;ASC TERT1: 102.2;HSkMC: 48.1;hTEC/SVTERT24-B: 30.1;U-138 MG: 29.1;WM-115: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Approved "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" 1.7 2.4 0.7 0.9 1.1 0.1 0.4 2.0 1.0 0.5 2.9 4.2 0.1 0.6 0.9 0.7 0.8 0.5 3.4 0.5 0.6 2.9 0.1 0.7 0.1 0.8 1.0 0.5 0.1 0.1 1.7 0.7 0.3 2.2 0.9 1.4 0.2 4.5 0.3 0.8 0.7 0.9 0.1 0.2 1.4 1.1 0.7 0.1 28.9 0.0 0.2 5.1 0.9 0.8 0.0 0.1 26.0 0.2 76.7 102.2 0.3 6.7 3.3 0.1 0.1 0.5 0.1 0.0 0.9 15.5 0.0 0.0 5.3 0.0 0.4 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 48.1 0.0 30.1 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 1.2 0.0 0.4 0.1 0.0 0.0 0.1 2.9 0.5 0.0 0.1 0.7 1.9 10.2 0.7 0.1 1.5 29.1 1.3 0.0 0.2 0.1 0.0 0.0 4.6 0.0 25.2 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.7 1.1 2.0 1.0 0.5 0.6 0.8 1.0 0.3 0.1 0.7 0.8 0.2 0.0 0.6 0.7 0.5 0.0 0.2 0.4 0.0 2.6 0.3 0.0 3.5 0.0 2.0 1.8 2.1 1.2 0.5 0.0 0.0 0.0 2.1 1.2 0.4 0.6 10.8 0.0 2.2 0.0 2.1 1.3 0.0 0.4 1.3 0.5 0.0 0.1 0.3 10.1 3.2 0.1 0.0 0.6 0.4 3.3 0.9 0.2 1.8 0.0 0.1 3.0 0.0 4.0 3.5 0.1 0.0 3.8 0.4 0.1 0.0 0.1 0.9 7.1 0.0 0.6 3.2 0.5 2.1 0.0 0.0 0.7 0.2 0.1 0.0 0.2 SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 491.6;liver: 484.7;skin 1: 447.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 267.4;Hepatocytes: 603.1;Squamous epithelial cells: 246.6;Syncytiotrophoblasts: 250.8;Urothelial cells: 492.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 7 "midbrain: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 482.2;hTCEpi: 436.6;U-251 MG: 470.0;U-266/70: 467.4;U-266/84: 1069.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" NA NA 63100000 3100000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 22: Epithelial cell types - Mixed function" "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" 2.4 17.4 0.7 17.2 0.2 1.2 23.8 2.3 0.8 127.2 0.7 61.8 75.8 2.2 19.9 491.6 10.5 77.1 0.6 0.3 2.0 99.5 484.7 59.6 7.3 0.6 17.3 1.6 16.6 5.4 2.0 32.6 0.8 56.3 33.3 0.7 85.8 25.9 1.6 447.4 53.6 2.2 0.2 20.1 87.3 3.3 2.5 5.1 18.3 0.0 43.2 104.8 242.1 0.1 252.6 137.6 42.7 108.1 11.6 1.6 134.9 68.7 65.4 62.7 52.8 29.5 148.9 0.3 24.8 48.8 34.8 241.4 19.0 482.2 41.8 1.3 12.5 0.0 12.2 150.2 10.3 11.0 1.0 6.4 436.6 56.5 132.9 87.2 6.9 0.0 6.4 94.7 34.0 149.6 0.6 2.6 38.7 189.6 263.1 5.3 15.7 189.9 80.5 370.0 12.4 99.7 51.9 342.4 15.2 17.1 34.5 2.8 10.7 246.9 78.6 9.2 470.0 467.4 1069.8 1.0 74.5 0.6 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 2.3 0.8 0.3 2.0 0.6 17.3 0.8 0.2 2.5 0.1 0.4 93.0 99.0 0.0 33.0 113.9 189.1 162.8 81.4 0.6 29.9 26.7 0.9 267.4 161.8 42.3 0.0 3.8 0.7 147.2 31.3 61.3 0.1 16.6 5.0 3.5 10.8 13.5 0.3 21.8 46.3 5.0 55.0 22.9 6.3 7.5 7.5 603.1 2.3 21.9 0.2 73.1 50.8 10.6 11.9 0.3 0.6 2.5 21.4 0.0 0.6 0.3 0.0 1.0 0.0 111.4 78.0 1.2 165.1 78.0 106.5 88.5 43.4 0.4 0.0 0.1 15.0 1.0 14.0 246.6 229.0 250.8 4.0 0.1 85.1 492.8 SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 515.9;Pancreatic endocrine cells: 476.4;Suprabasal keratinocytes: 472.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 512.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 320000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" 68.0 73.1 90.3 26.3 116.8 10.1 113.1 90.2 120.7 53.0 68.5 102.6 37.8 53.0 11.8 124.3 76.6 72.2 65.9 66.4 90.2 166.9 410.9 168.3 9.8 120.5 127.8 26.3 90.3 34.7 43.2 27.3 95.4 53.0 62.6 35.1 103.7 45.9 101.5 190.4 42.4 53.8 89.9 32.3 140.1 47.1 151.9 8.2 51.1 35.4 35.2 124.7 68.7 71.4 162.1 20.7 11.1 0.8 269.2 164.3 474.4 201.5 273.0 222.9 158.6 242.7 400.0 0.2 88.1 255.4 224.5 203.1 8.2 512.2 269.0 46.7 7.4 4.9 15.8 95.8 292.4 1.0 8.2 223.1 336.5 92.4 223.2 123.3 29.9 3.7 8.2 0.5 130.5 159.9 0.2 14.2 20.4 139.9 63.1 0.3 99.7 0.6 367.7 211.7 4.3 15.6 277.2 169.4 51.4 125.2 123.1 9.7 56.4 169.4 141.4 17.3 131.8 8.5 6.7 0.7 266.2 16.4 103.2 1.5 1.6 0.4 0.7 0.6 2.1 0.3 2.0 0.8 1.5 0.3 0.4 0.5 0.8 0.7 0.6 1.4 4.4 0.7 90.3 116.8 90.2 120.7 66.4 90.2 120.5 127.8 95.4 89.9 151.9 71.4 21.9 291.7 391.2 106.7 3.8 373.7 322.2 352.8 75.1 14.5 208.8 90.6 59.3 245.9 218.4 189.4 12.5 38.9 7.8 174.3 64.6 296.0 1.2 116.6 20.8 16.0 55.1 7.4 0.2 515.9 230.0 43.0 170.7 179.0 13.9 10.8 11.4 260.6 18.8 0.0 0.3 131.9 160.7 19.3 106.0 3.8 4.1 39.5 76.5 5.6 33.0 10.0 0.0 3.5 1.8 476.4 121.7 5.3 2.1 284.2 59.0 153.8 178.6 23.6 0.0 34.9 33.5 1.8 2.5 170.9 472.8 67.5 16.8 3.2 90.7 423.9 SECTM1 K12 ENSG00000141574 "Secreted and transmembrane 1" Q8WVN6 17 82321024-82334074 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 90.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.4;Kupffer cells: 52.7;Macrophages: 36.8;Paneth cells: 48.2;Proximal enterocytes: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 154.2" "Group enriched" "Detected in many" 13 "granulocytes: 154.2;monocytes: 58.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 83.3;BJ hTERT+: 86.7;BJ hTERT+ SV40 Large T+: 66.1;BJ hTERT+ SV40 Large T+ RasG12V: 64.4;PC-3: 70.2;SiHa: 122.5;SK-BR-3: 66.9;U-2197: 92.8" "Low region specificity" "Detected in some" HPA051214 Approved "Secreted to blood" NA NA 16000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA051214: AB_2732565" "unprognostic (2.42e-1)" "unprognostic (2.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.15e-2)" "unprognostic (4.55e-2)" "unprognostic (9.39e-2)" "unprognostic (3.17e-3)" "unprognostic (7.75e-3)" "unprognostic (2.10e-2)" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.43e-1)" "unprognostic (4.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" 20.7 4.0 1.4 40.5 1.3 11.7 13.0 1.1 2.9 15.0 2.4 36.7 66.8 11.0 1.7 12.8 14.3 12.4 5.9 1.3 2.0 35.9 5.9 28.7 17.4 3.4 1.9 5.8 4.1 1.9 2.4 13.1 2.7 13.9 23.6 0.1 34.6 5.7 2.4 15.9 90.4 14.6 1.8 42.4 24.4 1.6 2.1 5.8 3.8 2.5 8.5 17.8 13.4 1.9 20.4 4.5 0.0 1.4 33.3 83.3 1.7 9.9 86.7 66.1 64.4 2.1 40.9 0.0 0.4 29.1 1.0 60.4 0.0 4.0 2.5 6.5 0.2 8.3 28.2 5.5 25.4 0.0 0.0 35.8 8.6 3.6 1.5 4.9 1.9 0.2 0.3 0.1 42.7 0.8 0.1 0.1 0.2 5.3 70.2 0.0 0.5 1.0 19.0 0.1 4.5 0.5 122.5 66.9 1.5 0.2 5.6 1.8 0.7 7.5 0.6 92.8 0.1 0.3 0.0 0.1 1.7 0.0 0.4 0.1 30.9 0.0 0.4 58.2 0.3 0.0 0.6 0.2 8.3 0.0 0.1 0.1 154.2 0.0 56.3 3.5 0.0 4.5 1.4 1.3 1.1 2.9 1.3 2.0 3.4 1.9 2.7 1.8 2.1 1.9 8.2 12.8 2.4 0.0 1.0 9.4 4.6 0.8 5.2 0.0 4.4 1.5 0.9 0.0 3.0 1.8 0.0 0.3 1.8 63.4 0.0 9.5 0.1 3.0 4.4 6.0 0.0 0.0 0.0 9.9 0.9 6.1 8.6 7.3 1.3 0.0 3.6 1.3 7.1 0.0 0.0 8.7 2.0 52.7 10.7 0.4 5.3 36.8 1.8 0.0 19.5 0.0 1.0 0.0 0.0 5.4 48.2 0.0 1.1 19.5 62.5 3.2 3.6 0.0 0.0 0.6 1.8 0.1 0.2 0.9 3.4 0.3 1.1 0.0 1.3 21.3 SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2087.6;liver: 6268.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 448.7;Alveolar cells type 2: 529.3;Granulosa cells: 458.1;Hofbauer cells: 858.5;Macrophages: 373.3;Proximal tubular cells: 1044.7" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Hep G2: 567.4;HSkMC: 451.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 2220000000 1800000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" 719.1 424.3 164.8 179.9 345.6 40.1 617.5 386.0 290.0 460.0 145.5 644.0 620.0 335.8 459.7 240.7 376.5 670.5 237.2 156.3 231.3 853.7 6268.1 512.0 552.4 519.4 316.4 701.2 229.0 246.0 108.3 973.0 490.3 214.2 714.2 59.2 170.8 374.1 156.4 171.8 2087.6 233.2 310.3 948.8 257.0 87.8 284.7 170.4 147.0 265.6 177.4 414.3 213.1 524.3 0.7 1.7 7.7 1.0 43.6 12.2 7.3 4.1 10.9 0.0 0.0 12.5 65.3 2.0 36.3 1.5 1.4 1.7 0.2 0.1 0.0 2.4 52.7 3.1 0.2 567.4 25.9 3.2 0.4 451.1 0.7 0.0 0.1 1.9 0.1 1.5 6.4 12.9 23.5 1.3 1.1 6.4 30.6 17.0 0.9 1.3 2.0 100.8 12.5 8.0 2.2 2.7 2.7 16.7 1.6 54.6 125.4 0.7 0.7 3.2 1.7 5.2 1.0 8.4 1.5 2.0 1.7 5.9 1.5 0.1 0.1 0.5 0.5 0.1 0.6 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.5 0.6 0.2 0.9 0.3 0.3 164.8 345.6 386.0 290.0 156.3 231.3 519.4 316.4 490.3 310.3 284.7 524.3 312.7 448.7 529.3 0.0 15.2 0.0 0.0 0.0 0.0 0.0 312.0 271.1 0.0 0.0 102.1 125.0 0.0 223.4 9.4 0.0 197.6 73.4 0.0 83.8 231.0 75.8 0.0 0.0 0.0 52.8 17.5 358.7 0.0 116.1 26.5 458.1 0.0 0.0 858.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 373.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 4.9 0.0 0.0 1044.7 52.5 0.0 0.0 0.0 133.1 0.0 0.0 0.0 0.0 112.9 10.0 361.8 0.0 0.0 SEMA3A "coll-1, Hsema-I, SEMA1, SEMAD, SemD" ENSG00000075213 "Semaphorin 3A" Q14563 7 83955777-84492724 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.6" "Cell type enhanced" "Detected in many" "Astrocytes: 58.4;Cone photoreceptor cells: 45.9;Excitatory neurons: 89.7;Rod photoreceptor cells: 66.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.5" "Lineage enriched" "Detected in single" 16 "monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 129.3;BJ: 102.9;fHDF/TERT166: 112.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029447, HPA052235" Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029447: AB_10602302, HPA052235: AB_2681770" "unprognostic (1.20e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.51e-1)" "unprognostic (5.82e-2)" "unprognostic (1.37e-2)" "unprognostic (5.98e-3)" "unprognostic (2.92e-3)" "unprognostic (6.05e-3)" "unprognostic (1.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.44e-2)" "unprognostic (6.18e-12)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.61e-2)" "unprognostic (1.47e-4)" 6.8 0.2 3.8 3.8 5.8 0.1 1.5 0.6 3.0 4.4 0.0 9.8 1.4 1.0 2.2 5.8 1.6 5.6 2.5 2.0 0.7 0.4 0.4 2.3 3.3 3.8 0.2 0.4 0.4 0.5 2.1 10.4 4.6 2.9 5.7 22.6 0.4 0.4 0.1 1.1 2.4 4.7 0.6 3.8 2.0 1.2 0.3 0.5 1.7 0.5 1.6 5.4 0.6 4.4 11.8 32.8 129.3 0.1 3.8 3.1 8.4 102.9 60.0 8.5 5.3 11.4 30.7 0.0 4.8 112.0 1.1 57.0 0.3 24.6 11.8 0.0 4.2 0.0 6.0 0.0 3.3 2.6 0.0 3.9 0.0 18.1 4.4 26.2 32.1 0.1 0.1 0.2 3.4 0.6 0.0 0.0 48.6 0.5 11.6 2.3 55.3 3.4 18.5 0.8 9.8 5.2 0.8 0.2 1.1 20.7 0.6 1.1 18.3 11.2 11.6 32.6 15.1 7.6 5.5 0.0 11.5 4.5 22.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.8 5.8 0.6 3.0 2.0 0.7 3.8 0.2 4.6 0.6 0.3 4.4 1.0 3.2 1.7 58.4 0.0 0.9 0.0 15.4 0.0 15.1 0.2 0.3 6.0 0.0 22.4 0.0 45.9 0.4 0.3 0.1 0.0 0.1 0.2 2.0 0.7 7.3 0.0 0.0 89.7 2.0 0.2 9.3 0.0 9.0 1.3 3.5 1.8 0.1 1.0 3.3 10.0 0.0 2.0 0.3 2.7 0.2 2.5 0.5 1.8 7.5 0.0 19.6 0.0 9.5 5.8 5.5 0.0 0.0 0.0 0.3 0.0 0.0 15.6 66.3 0.0 1.5 2.1 1.7 1.9 0.4 1.3 0.3 1.1 18.6 0.0 0.2 SEMA3B "LUCA-1, SemA, sema5, SEMAA, semaV" ENSG00000012171 "Semaphorin 3B" Q13214 3 50267558-50277546 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 174.5;brain: 184.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.5;Distal enterocytes: 129.1;Gastric mucus-secreting cells: 208.0;Oligodendrocytes: 157.8;Proximal enterocytes: 336.4;Syncytiotrophoblasts: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 73.7;Hep G2: 105.7;SK-BR-3: 54.5;WM-115: 173.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 27.9" HPA030651 Uncertain "Secreted in other tissues" NA NA 790000 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" "HPA030651: AB_10602224" "prognostic favorable (1.27e-4)" "unprognostic (6.48e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (4.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.28e-1)" "unprognostic (1.85e-2)" "unprognostic (4.27e-1)" "unprognostic (7.99e-2)" "unprognostic (7.78e-2)" "unprognostic (3.89e-1)" "unprognostic (8.87e-3)" "unprognostic (1.69e-2)" 33.6 174.5 50.2 9.0 124.4 0.2 17.3 87.7 78.2 46.2 35.2 53.6 41.3 45.7 2.2 9.1 37.0 10.0 40.3 53.1 66.4 70.9 6.1 49.2 0.3 125.7 101.9 24.5 41.4 10.6 10.4 35.3 98.6 34.0 10.5 2.0 12.7 20.6 7.4 7.9 62.8 14.2 76.2 5.1 56.8 14.8 110.4 0.6 24.2 8.7 0.3 19.6 32.3 184.2 12.7 8.2 0.8 8.0 0.6 1.0 2.0 16.3 22.3 4.7 7.9 5.5 29.7 0.0 14.3 15.3 0.0 1.8 0.4 26.2 1.8 0.2 0.7 0.0 73.7 105.7 16.8 0.0 0.8 5.1 0.5 5.4 4.1 19.9 0.0 0.1 0.2 2.2 0.8 22.4 0.0 0.7 1.1 23.4 4.5 0.3 1.2 0.6 7.4 1.4 1.0 3.8 4.2 54.5 9.2 2.4 3.6 0.1 0.5 1.3 15.4 4.3 5.3 4.4 0.2 0.2 7.9 0.2 173.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.2 124.4 87.7 78.2 53.1 66.4 125.7 101.9 98.6 76.2 110.4 184.2 6.5 163.5 18.6 45.1 1.8 0.0 8.3 0.0 6.2 3.7 19.3 8.5 14.5 44.3 18.6 64.4 0.0 3.6 1.2 129.1 1.9 38.3 11.2 29.8 11.6 6.1 10.3 0.0 0.6 23.1 1.0 35.3 208.0 73.1 11.4 11.4 5.7 1.2 1.9 0.0 0.8 45.7 0.0 1.6 0.0 21.4 4.1 2.8 0.0 12.2 0.7 17.3 0.0 3.0 157.8 32.5 79.9 3.0 0.6 14.1 336.4 40.4 5.1 1.6 6.6 19.0 7.5 6.6 11.4 2.0 0.0 111.6 2.4 0.2 31.5 32.7 SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 92.2;Breast myoepithelial cells: 93.5;Fibroblasts: 109.6;Ionocytes: 91.6;Oligodendrocytes: 223.7;Respiratory ciliated cells: 103.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.6" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.6" "Cell line enhanced" "Detected in many" "GAMG: 252.7;RT4: 238.3;T-47d: 267.0;U-2197: 349.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 13000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: AB_10797389" "unprognostic (1.93e-2)" "unprognostic (2.54e-3)" "unprognostic (4.94e-1)" "unprognostic (9.86e-2)" "unprognostic (6.74e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (9.28e-3)" "unprognostic (1.91e-3)" "unprognostic (1.39e-2)" "unprognostic (9.01e-2)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.07e-2)" "unprognostic (1.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-2)" 53.8 9.5 4.9 12.7 8.1 0.8 57.3 9.1 5.5 53.0 2.6 38.4 10.6 42.7 23.1 20.5 15.4 30.0 22.1 11.0 12.7 10.0 1.3 18.4 1.0 15.0 8.0 48.5 2.6 0.8 3.7 6.0 17.5 66.6 31.3 1.0 27.3 42.3 19.3 17.9 14.1 44.4 10.0 22.2 20.6 12.9 8.4 1.4 1.8 34.3 1.1 69.8 14.4 12.8 6.6 77.0 156.4 0.6 35.2 82.5 0.3 51.8 59.7 25.9 32.5 12.4 144.7 0.0 2.1 17.7 252.7 31.2 0.7 47.0 42.4 0.1 15.8 9.9 63.6 0.7 41.3 0.7 0.2 36.1 32.3 63.6 62.0 220.2 0.5 0.0 0.5 0.1 46.4 113.7 0.2 0.3 1.4 22.2 12.2 0.1 75.5 1.2 142.9 238.3 0.8 82.4 145.7 38.9 9.5 66.3 267.0 0.2 125.2 140.1 64.2 349.2 93.9 1.2 0.0 0.1 52.8 0.0 142.3 49.6 5.7 0.9 0.0 2.4 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 2.6 0.0 1.9 3.3 0.0 1.7 4.9 8.1 9.1 5.5 11.0 12.7 15.0 8.0 17.5 10.0 8.4 12.8 7.4 9.6 8.9 3.3 0.3 26.4 41.8 92.2 10.8 0.3 15.8 93.5 38.2 1.5 39.8 7.3 6.2 0.5 1.7 56.1 1.9 3.8 0.5 20.3 11.9 7.7 6.0 4.6 41.7 6.6 1.3 109.6 17.9 34.4 5.1 13.2 1.1 0.0 8.8 0.0 16.7 15.7 91.6 3.1 14.9 2.3 7.8 9.0 55.2 20.6 8.3 1.5 1.0 3.0 223.7 68.2 12.4 52.3 0.0 53.7 12.5 0.4 103.0 0.6 0.0 38.8 17.3 0.7 2.7 3.0 18.9 0.3 1.5 9.9 30.4 70.0 SEMA3D "coll-2, Sema-Z2" ENSG00000153993 "Semaphorin 3D" O95025 7 84995553-85186855 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 47.8;thyroid gland: 45.4" "Cell type enhanced" "Detected in many" "Early spermatids: 157.4;Leydig cells: 52.5;Peritubular cells: 62.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 28.4;HaCaT: 28.7;TIME: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037522 Uncertain Approved "Golgi apparatus,Plasma membrane" "Secreted in other tissues" NA NA 120000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane" "HPA037522: AB_10672494" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (7.58e-3)" "unprognostic (4.02e-3)" "unprognostic (9.94e-2)" "unprognostic (5.62e-2)" "unprognostic (1.63e-1)" "unprognostic (9.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (5.25e-3)" 3.2 2.9 5.9 1.0 1.9 0.0 5.9 0.8 4.6 5.6 0.0 2.8 1.8 2.4 2.6 1.7 5.1 1.7 2.2 6.2 4.7 3.8 1.0 3.6 3.3 2.3 8.9 1.9 0.7 0.2 0.5 0.7 2.2 8.3 3.4 2.2 4.3 1.9 0.0 2.4 3.3 1.4 3.0 47.8 3.3 3.8 3.2 0.3 45.4 0.9 1.4 3.1 0.7 3.2 0.0 0.0 12.1 0.0 0.0 0.0 0.5 7.6 8.2 8.8 4.2 0.0 0.0 0.0 2.2 28.4 0.2 28.7 3.1 0.0 5.8 0.0 5.8 0.0 3.1 0.0 0.1 0.0 0.0 0.1 0.0 1.5 7.2 10.1 13.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.6 7.5 2.1 8.9 6.8 2.8 0.0 0.1 1.1 0.0 0.0 0.4 13.8 0.4 0.0 44.2 0.0 2.7 0.4 0.0 5.4 3.4 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 0.8 4.6 6.2 4.7 2.3 8.9 2.2 3.0 3.2 3.2 2.8 0.0 3.3 18.3 1.8 3.6 2.4 0.1 0.0 2.6 0.8 8.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 157.4 1.6 0.3 14.8 26.5 0.0 12.3 0.2 0.0 15.3 0.0 4.3 2.5 0.2 2.9 0.0 1.3 1.7 5.1 0.7 2.0 0.0 5.7 23.3 52.5 0.5 12.4 19.7 0.0 1.9 0.0 3.0 0.9 0.0 0.0 62.4 0.0 5.8 1.9 4.7 0.8 4.1 0.0 0.7 2.0 0.7 0.8 0.1 2.4 0.0 0.5 11.2 1.0 0.4 SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 110.2;Bipolar cells: 75.7;Excitatory neurons: 84.9;Oligodendrocyte precursor cells: 250.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 3.9;SK-BR-3: 19.9;U-2 OS: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029419: AB_10602090, HPA063804: AB_2685127" "unprognostic (4.42e-2)" "unprognostic (1.48e-2)" "unprognostic (7.82e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-1)" "unprognostic (4.27e-2)" "unprognostic (9.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.25e-1)" "unprognostic (1.42e-1)" "unprognostic (9.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-6)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" 1.2 0.1 3.1 0.2 2.8 0.0 2.8 0.6 2.3 1.8 0.1 2.1 0.6 1.9 0.3 1.2 0.6 2.3 0.1 5.0 5.3 0.1 0.1 2.2 0.0 1.6 4.3 0.1 0.4 0.0 0.2 0.2 1.3 4.3 1.7 3.9 2.2 3.3 0.2 0.5 1.2 1.1 3.2 0.0 1.3 0.0 4.3 1.7 0.6 1.0 0.1 3.2 0.7 3.7 0.2 1.1 0.2 0.0 0.5 3.1 0.0 0.0 0.2 0.2 0.3 0.0 0.3 0.0 0.0 0.0 0.5 0.0 3.4 0.0 1.3 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.9 0.0 0.0 0.5 0.4 1.1 0.0 2.0 0.0 0.0 0.8 0.1 0.0 0.0 19.9 0.0 3.2 1.6 0.0 0.0 0.7 6.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 2.8 0.6 2.3 5.0 5.3 1.6 4.3 1.3 3.2 4.3 3.7 10.5 176.3 110.2 2.9 0.2 1.1 1.3 1.6 0.0 75.7 19.0 7.5 1.7 18.6 43.2 1.8 0.0 0.8 0.2 0.1 0.0 3.9 1.1 3.8 1.2 10.7 0.0 0.0 84.9 1.1 0.4 21.3 3.1 9.3 24.0 0.2 0.0 0.3 0.1 0.0 12.3 0.0 4.1 1.0 2.1 0.0 0.9 3.6 1.8 1.0 1.0 29.6 0.0 250.3 6.0 6.2 0.0 0.0 0.3 2.6 0.1 0.5 35.7 3.6 0.0 0.8 1.0 0.3 0.6 0.3 0.4 0.3 2.8 0.0 0.0 2.5 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 80.1;breast: 64.2" "Cell type enriched" "Detected in many" 6 "Adipocytes: 151.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "ASC diff: 26.1;Hep G2: 7.1;HUVEC TERT2: 7.4;THP-1: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" NA NA 5600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA001761: AB_1079902" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "unprognostic (7.08e-2)" "unprognostic (1.47e-2)" "unprognostic (2.85e-1)" "unprognostic (5.79e-4)" "unprognostic (5.20e-3)" "unprognostic (9.14e-2)" "unprognostic (5.54e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-3)" "unprognostic (4.14e-1)" "prognostic favorable (8.86e-5)" "unprognostic (5.63e-2)" "unprognostic (2.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" 80.1 1.9 9.9 3.4 9.4 0.1 64.2 18.9 11.4 5.1 6.2 6.8 3.0 5.9 1.3 4.5 5.2 5.9 18.6 8.4 9.0 19.8 1.3 23.9 1.6 10.8 10.0 3.2 3.1 1.8 2.4 26.7 11.3 4.6 3.7 0.4 10.6 2.5 12.8 12.7 9.6 3.9 9.9 8.0 5.7 1.3 12.1 1.7 7.7 18.6 1.8 8.3 7.8 9.1 0.0 0.1 0.1 0.2 26.1 0.2 2.5 0.0 0.0 0.0 0.0 0.7 0.3 3.3 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 3.9 0.2 7.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 7.4 2.6 0.0 0.4 0.0 0.3 0.2 4.3 1.2 0.7 0.1 0.0 0.0 4.1 0.0 0.3 0.5 0.5 0.0 0.4 0.5 0.1 1.9 6.5 2.9 0.1 2.4 0.0 0.0 0.5 2.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 9.9 9.4 18.9 11.4 8.4 9.0 10.8 10.0 11.3 9.9 12.1 9.1 151.5 3.2 1.3 0.0 0.3 0.4 0.1 0.1 0.0 1.7 5.1 5.5 10.7 0.0 0.0 3.7 0.0 1.7 0.9 0.3 0.0 0.0 3.0 2.8 1.6 20.4 9.6 0.0 0.0 0.0 0.2 3.6 1.1 5.8 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.3 5.0 0.3 0.5 0.0 24.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.2 0.2 0.0 9.4 0.0 0.1 0.2 0.0 4.1 3.0 0.1 0.1 0.5 0.1 7.5 0.4 0.1 0.2 0.0 SEMG1 "CT103, SEMG" ENSG00000124233 "Semenogelin 1" P04279 20 45207033-45209768 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 147 "seminal vesicle: 30405.5" "Group enriched" "Detected in some" 18 "Basal prostatic cells: 7.5;Prostatic glandular cells: 3.4" "Cancer enriched" "Detected in some" 14 "prostate cancer: 20.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 239 "eosinophil: 26.8" "Lineage enriched" "Detected in single" 269 "granulocytes: 26.8" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;THP-1: 3.1" "HPA042476, HPA064892" Enhanced "Secreted in male reproductive system" NA NA 7000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" "HPA042476: AB_10794799, HPA064892: AB_2732724" "unprognostic (3.71e-1)" "unprognostic (2.92e-2)" "unprognostic (1.44e-1)" "unprognostic (3.32e-1)" "unprognostic (1.11e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.1 0.0 0.0 0.0 30405.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 SEMG2 SGII ENSG00000124157 "Semenogelin 2" Q02383 20 45221373-45224458 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 149 "seminal vesicle: 10407.9" "Group enriched" "Detected in some" 9 "Basal prostatic cells: 1.2;Collecting duct cells: 3.7;Early spermatids: 1.2;Late spermatids: 1.8;Prostatic glandular cells: 1.9" "Cancer enriched" "Detected in single" 25 "prostate cancer: 9.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042767, HPA042835" Enhanced "Secreted in male reproductive system" NA NA 5000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 22: Epithelial cell types - Mixed function" "HPA042767: AB_10959312, HPA042835: AB_10964060" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.8 0.0 0.0 0.0 10407.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 45 "liver: 34022.4" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 42919.3" "Cancer enriched" "Detected in all" 10 "liver cancer: 3850.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2482.1;intermediate monocyte: 3411.9;neutrophil: 2823.2;non-classical monocyte: 4518.8" "Group enriched" "Detected in all" 5 "granulocytes: 2823.2;monocytes: 4518.8" "Cell line enriched" "Detected in many" 10 "Hep G2: 4769.1" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "cerebellum: 130.6" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 2070000000000 140000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB013211: , CAB016648: AB_1611888, CAB073396: , HPA000927: AB_1844761, HPA001292: AB_1844762" "prognostic favorable (1.61e-5)" "unprognostic (3.37e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.50e-3)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.96e-1)" 49.1 9.7 7.3 225.0 7.1 157.1 100.6 9.1 21.3 105.7 11.1 151.0 278.6 42.3 5.3 10.1 22.4 352.3 12.5 7.3 11.1 621.2 34022.4 570.7 37.0 20.9 14.4 5.4 201.0 5.2 9.1 26.6 15.8 12.6 178.8 2.6 33.6 140.5 3.7 8.2 760.9 75.7 12.2 313.6 282.5 3.0 16.2 15.0 23.0 11.9 25.2 55.8 9.1 16.9 25.9 0.3 0.0 0.5 1.0 0.0 1.5 0.6 1.7 0.6 1.1 187.8 500.8 2.6 15.6 0.0 1.4 1.9 0.0 10.9 1.2 70.1 0.0 4.3 2.0 4769.1 0.3 16.8 2.3 4.1 5.4 0.3 18.5 1.9 0.0 0.0 3.2 0.4 0.0 0.8 1.1 12.1 2.0 5.5 8.0 1.9 16.7 2.4 300.8 3.0 0.6 1.3 6.4 1.6 1.4 0.4 262.1 2.7 1.6 2.1 59.4 1.9 7.1 3.3 1.8 7.0 4.4 41.8 0.6 10.6 2482.1 634.3 5.5 3411.9 6.8 7.7 3.6 4.1 683.6 3.6 4.3 3.6 2823.2 5.3 4518.8 14.9 4.5 2770.7 7.3 7.1 9.1 21.3 7.3 11.1 20.9 14.4 15.8 12.2 16.2 16.9 2.2 35.3 285.9 0.0 137.4 2.3 1.0 36.3 0.0 0.2 100.8 31.5 5.3 4520.9 165.5 150.8 0.0 1.6 3.9 52.0 68.4 3787.9 0.2 70.0 2.8 57.0 12.1 1227.4 0.0 225.8 4.5 3.6 36.2 51.3 1.3 0.1 938.8 42919.3 167.6 0.0 0.0 742.4 30.5 1454.0 74.1 1.1 0.0 413.3 1.8 1.0 291.7 0.3 9.2 0.0 0.0 2161.6 137.0 0.0 1.5 6.8 5270.0 745.9 108.3 0.2 0.0 0.6 17.4 0.0 0.2 0.6 1.7 6.4 75.5 0.0 83.2 6.7 SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "liver: 346.9" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 259.1" "Cancer enriched" "Detected in some" 51 "liver cancer: 40.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 21.2" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 3960000000 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Cytosol "HPA048739: AB_2797237" "unprognostic (7.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.00e-4)" "unprognostic (6.11e-2)" "unprognostic (2.81e-4)" "unprognostic (2.31e-4)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (7.93e-3)" 0.4 0.4 0.4 0.6 0.7 3.3 0.6 3.2 1.4 0.6 0.4 0.7 0.7 0.7 0.5 0.4 0.3 0.5 0.6 0.4 0.4 0.5 346.9 0.4 0.8 1.5 0.5 0.9 0.5 0.2 0.2 0.5 0.8 0.4 0.7 3.1 0.4 0.4 0.5 1.7 0.7 0.6 0.4 0.7 0.7 0.6 0.7 1.3 0.7 0.4 0.4 0.2 0.1 2.5 0.6 0.2 1.8 0.7 0.7 0.6 0.4 0.5 0.5 0.9 0.8 2.7 0.6 2.1 0.3 0.4 0.2 0.4 2.2 0.5 1.3 0.8 1.4 2.0 0.8 21.2 0.4 1.6 1.1 0.6 0.5 0.3 0.7 1.1 1.0 1.1 0.5 1.3 1.0 0.3 1.4 0.8 0.8 0.2 0.6 0.9 1.2 0.9 0.5 0.7 0.9 0.8 0.4 0.4 0.2 1.0 0.9 0.9 0.6 0.7 0.4 0.7 0.6 1.1 0.5 0.9 0.9 1.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 3.2 1.4 0.4 0.4 1.5 0.5 0.8 0.4 0.7 2.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 2.8 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 6.6 8.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 3.3 259.1 0.0 0.0 0.0 0.4 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SERPINA11 ENSG00000186910 "Serpin family A member 11" Q86U17 14 94442464-94452800 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 92 "liver: 490.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 278.7" "Cancer enriched" "Detected in some" 9 "liver cancer: 94.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 17.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 230000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.50e-2)" "unprognostic (3.26e-1)" "unprognostic (9.00e-2)" "prognostic favorable (6.30e-4)" "unprognostic (7.44e-2)" "unprognostic (2.02e-2)" "unprognostic (1.70e-1)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 5.3 0.0 0.0 0.0 0.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 490.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 3.9 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.3 0.0 0.0 4.3 1.8 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.6 278.7 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.2 SERPINA12 "OL-64, Vaspin" ENSG00000165953 "Serpin family A member 12" Q8IW75 14 94487274-94517844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 396.4" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 20.9" "Group enriched" "Detected in some" 5 "liver cancer: 1.8;melanoma: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "Hep G2: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 6500000 "Cluster 61: Skin - Cornification" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.82e-3)" "unprognostic (6.44e-2)" "unprognostic (3.25e-1)" "unprognostic (1.00e-2)" "unprognostic (5.98e-2)" "unprognostic (2.97e-2)" "unprognostic (7.64e-3)" "unprognostic (6.67e-2)" 0.3 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 396.4 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 9176.5;pancreas: 4910.2" "Cell type enhanced" "Detected in some" "Ductal cells: 20.9;Exocrine glandular cells: 33.0;Fibroblasts: 68.6;Late spermatids: 12.2;Pancreatic endocrine cells: 18.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "Hep G2: 449.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" NA NA 697000000000 94000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" 91.8 58.0 100.4 43.4 116.5 2.1 371.0 117.7 293.8 368.8 110.3 79.5 11.7 44.9 11.5 42.5 116.6 146.0 311.7 103.6 320.0 215.5 9176.5 169.9 5.0 196.3 183.1 181.5 4910.2 1.0 271.2 14.6 138.3 580.5 13.3 131.5 1505.8 54.9 177.8 55.7 91.6 83.1 141.4 31.7 290.5 66.9 176.3 2.6 72.6 38.9 6.4 207.4 70.4 173.0 0.2 0.5 0.0 0.3 0.2 0.8 0.3 0.1 0.1 0.0 0.0 1.2 4.9 0.6 4.5 0.0 3.3 0.9 0.0 4.4 0.0 2.7 0.0 1.0 0.2 449.9 56.9 1.9 0.7 52.0 63.9 0.0 2.5 5.4 0.0 0.0 0.3 0.2 0.0 17.1 0.5 0.5 0.8 1.6 0.0 0.6 2.2 0.2 3.8 0.2 0.1 0.0 1.8 2.5 65.6 0.4 2.4 0.0 0.6 0.0 8.5 0.1 19.4 1.1 2.0 2.1 0.4 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 116.5 117.7 293.8 103.6 320.0 196.3 183.1 138.3 141.4 176.3 173.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.5 1.8 0.0 5.6 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 20.9 3.7 0.2 0.1 0.3 0.0 0.0 0.0 33.0 0.0 68.6 9.7 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.3 0.0 0.0 1.0 0.2 0.0 0.0 0.0 18.7 0.0 0.4 0.3 0.5 0.0 0.1 1.5 0.0 0.0 1.7 0.8 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 SERPINA4 "KAL, kallistatin, KLST, KST, PI4" ENSG00000100665 "Serpin family A member 4" P29622 14 94561442-94569913 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 550.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 245.9;Exocrine glandular cells: 93.8;Hepatocytes: 478.5;Pancreatic endocrine cells: 62.1" "Cancer enriched" "Detected in many" 4 "liver cancer: 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 28.4" "Not detected" "Not detected" "HPA003607, HPA068939" Approved Uncertain Vesicles "Secreted to blood" NA NA 14500000000 14000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA003607: AB_1079914, HPA068939: " "unprognostic (1.65e-3)" "unprognostic (4.13e-2)" "prognostic favorable (2.95e-4)" "unprognostic (2.09e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (4.03e-3)" "unprognostic (1.02e-2)" "unprognostic (2.24e-4)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.4 41.0 0.0 1.5 53.4 0.0 0.0 0.0 7.3 550.0 0.0 0.0 0.0 0.0 0.0 116.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.3 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 245.9 0.0 3.7 0.0 0.0 0.0 0.0 11.7 30.0 0.0 3.3 0.3 0.3 0.0 2.7 0.0 93.8 0.0 0.0 5.1 4.5 0.0 0.2 5.3 478.5 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 62.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 400.4;Endometrial ciliated cells: 175.2;Glandular and luminal cells: 345.3;Hepatocytes: 198.2;Late spermatids: 277.8;Peritubular cells: 144.4" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" 5.1 484.5 1.8 3.3 2.4 0.0 19.6 2.2 1.7 29.6 3.0 5.3 5.5 31.8 1.2 0.8 26.3 160.5 19.0 1.6 7.2 151.4 785.6 1.0 3.6 3.5 3.8 30.1 173.9 0.2 3.2 0.1 5.3 6.8 1.9 14.0 9.4 153.3 46.4 3.3 3.6 2.1 1.7 112.2 12.1 432.4 2.8 0.9 4.1 152.6 4.7 2.3 4.0 3.7 0.8 0.1 2.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 12.0 12.2 0.0 8.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 261.3 0.3 0.4 0.0 1.7 0.3 0.1 0.0 2.3 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.5 0.2 3.9 0.1 0.4 17.4 0.2 0.1 7.9 0.9 0.1 0.0 0.5 0.0 0.6 0.4 1.5 0.2 0.1 0.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 2.2 1.7 1.6 7.2 3.5 3.8 5.3 1.7 2.8 3.7 0.9 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.2 18.9 14.1 0.8 400.4 0.1 33.1 2.1 0.0 0.1 0.0 64.6 103.2 78.7 175.2 19.7 40.3 0.0 2.7 0.0 122.2 0.0 18.2 0.5 345.3 0.0 78.2 2.5 198.2 0.0 8.4 0.0 0.0 0.0 3.2 0.7 277.8 57.2 1.9 0.0 0.0 0.6 5.4 0.0 0.0 0.2 18.3 0.0 144.4 0.0 0.1 0.0 7.5 0.0 1.4 6.6 11.6 1.5 11.1 2.9 0.0 0.6 0.3 1.8 58.7 0.0 0.1 SERPINA6 CBG ENSG00000170099 "Serpin family A member 6" P08185 14 94304248-94323389 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 776.6" "Group enriched" "Detected in some" 4 "Cholangiocytes: 204.5;Hepatocytes: 390.8" "Cancer enriched" "Detected in many" 9 "liver cancer: 244.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "T-47d: 961.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA017864 Approved "Secreted to blood" NA NA 60800000000 37000000000 "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "HPA017864: AB_1856721" "unprognostic (2.82e-2)" "unprognostic (1.67e-1)" "unprognostic (1.02e-3)" "prognostic favorable (6.96e-5)" "unprognostic (2.93e-3)" "unprognostic (9.98e-3)" "unprognostic (4.43e-2)" "unprognostic (3.11e-1)" "unprognostic (4.80e-3)" "unprognostic (2.94e-1)" "unprognostic (2.47e-2)" "unprognostic (4.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.14e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 1.9 0.0 3.5 0.1 0.5 0.0 0.0 12.6 35.1 0.0 0.0 0.0 43.5 776.6 0.1 0.0 0.0 0.0 0.3 17.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 114.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.4 4.5 0.1 0.4 0.0 0.1 0.7 0.0 0.0 961.9 0.0 0.0 0.5 0.0 0.6 0.0 0.3 0.0 0.5 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.1 0.7 0.0 0.0 4.4 0.0 0.4 204.5 0.3 0.0 0.0 0.3 0.0 0.4 1.9 33.1 0.0 62.6 0.3 0.4 9.0 16.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.2 9.7 390.8 0.0 0.0 0.0 0.8 2.0 8.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 1.0 1.2 0.0 0.0 0.0 0.1 43.0 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.8 0.1 SERPINA7 TBG ENSG00000123561 "Serpin family A member 7" P05543 X 106032435-106038727 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 612 "liver: 282.2" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 182.8" "Cancer enriched" "Detected in single" 203 "liver cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 475 "Hep G2: 69.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA002803 Approved "Secreted to blood" NA NA 39800000000 25000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA002803: AB_1079915" "unprognostic (6.22e-2)" "unprognostic (1.63e-3)" "unprognostic (3.34e-1)" "unprognostic (2.62e-1)" "unprognostic (2.15e-3)" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 282.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 182.8 0.0 0.0 0.0 0.7 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 SERPINA9 "CENTERIN, GCET1, SERPINA11b" ENSG00000170054 "Serpin family A member 9" Q86WD7 14 94462717-94479689 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "lymphoid tissue: 72.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "stomach cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 66 "Daudi: 69.5" "Region enriched" "Detected in many" 16 "basal ganglia: 71.8" "Secreted to blood" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (1.32e-2)" "unprognostic (1.05e-1)" "unprognostic (1.94e-2)" "unprognostic (3.89e-3)" "unprognostic (6.10e-2)" "unprognostic (6.67e-2)" "unprognostic (1.38e-2)" "unprognostic (1.16e-1)" 0.0 0.0 0.0 13.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 1.7 0.8 0.1 0.0 0.3 0.2 0.0 0.0 1.4 0.0 0.0 72.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SERPINB1 "anti-elastase, EI, ELANH2, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 466.8;esophagus: 478.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1424.3;Pancreatic endocrine cells: 1067.8;Urothelial cells: 984.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.3;OE19: 162.5;U-937: 144.9" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cytoplasmic bodies" "HPA018871: AB_1856724, HPA018882: , HPA052642: AB_2681896" "unprognostic (1.13e-2)" "unprognostic (1.93e-1)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-3)" "unprognostic (9.67e-2)" "unprognostic (3.59e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.88e-2)" "unprognostic (1.08e-3)" "unprognostic (9.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" 36.6 54.4 10.7 69.7 14.4 466.8 25.0 11.1 14.0 55.6 17.3 77.7 140.4 15.6 22.2 478.3 35.8 57.4 26.8 10.7 12.7 33.2 32.1 81.7 51.3 15.1 13.0 18.1 232.1 29.8 32.9 27.0 14.6 15.9 87.5 13.4 99.6 16.9 54.2 15.8 107.3 24.9 13.6 67.4 97.9 7.1 13.7 31.9 30.7 22.9 122.8 88.6 112.4 14.8 42.9 49.7 2.7 0.3 10.6 21.8 41.2 11.8 36.1 14.5 26.1 47.1 125.3 0.3 86.6 26.6 15.6 26.8 4.8 11.4 11.1 59.4 7.5 76.6 16.0 37.0 37.2 13.5 46.2 26.8 18.4 7.3 3.3 7.2 48.7 0.0 27.1 9.9 13.4 19.9 1.7 35.4 4.5 162.5 22.1 3.9 0.5 44.4 51.0 9.3 8.8 4.8 28.8 11.2 64.2 5.9 5.6 43.2 29.1 4.6 10.4 10.2 3.6 0.1 2.2 0.5 17.4 144.9 2.4 118.0 207.1 109.4 53.3 103.7 45.8 43.5 48.1 48.4 150.4 32.3 47.4 50.6 182.3 85.1 82.8 48.6 58.5 175.8 10.7 14.4 11.1 14.0 10.7 12.7 15.1 13.0 14.6 13.6 13.7 14.8 79.9 240.4 269.9 0.7 90.7 35.1 165.1 699.1 38.1 4.2 55.0 51.2 17.6 72.9 420.9 46.0 2.1 124.5 120.8 264.1 56.7 490.3 1.7 210.6 28.7 118.9 96.3 176.3 0.9 1424.3 149.1 89.1 345.1 104.5 452.2 32.1 124.9 20.2 183.0 10.1 0.9 263.1 109.9 332.7 308.2 3.5 34.8 387.3 71.2 15.9 589.7 48.3 139.0 4.5 6.6 1067.8 308.4 27.8 65.2 147.5 333.7 81.3 343.8 17.2 13.1 109.7 67.2 2.0 11.2 461.5 38.1 99.7 112.9 59.2 242.6 984.3 SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1341 "liver: 5056.6" "Cell type enriched" "Detected in some" 49 "Hepatocytes: 2707.9" "Cancer enriched" "Detected in some" 871 "liver cancer: 1504.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 37 "Hep G2: 84.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" NA NA 120000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB016790: , HPA001816: AB_1079926, HPA024007: AB_1856732" "unprognostic (1.28e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-2)" "unprognostic (5.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.93e-2)" "prognostic favorable (3.40e-5)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.48e-2)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-2)" "unprognostic (5.28e-3)" "unprognostic (5.80e-2)" "unprognostic (6.35e-2)" "unprognostic (8.21e-2)" 0.3 0.1 0.2 0.0 0.3 0.0 0.1 0.3 0.3 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.3 0.2 3.7 5056.6 0.3 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.1 0.3 0.1 0.0 0.7 0.1 0.0 0.3 0.1 0.2 0.0 0.2 1.5 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 84.2 0.0 1.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.2 1.8 0.1 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.0 1.0 0.1 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.2 0.3 0.1 3.2 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 37.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 1.6 0.0 34.7 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.1 42.1 2707.9 0.2 0.0 0.1 0.0 0.0 55.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 4.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.3 3.7 0.0 0.0 0.2 SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 1253.1" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 283.7" "Cancer enriched" "Detected in many" 80 "liver cancer: 334.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "Hep G2: 208.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" NA NA 50000000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB008639: AB_1618010, HPA055767: AB_2682912" "unprognostic (1.68e-1)" "unprognostic (8.27e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.09e-4)" "unprognostic (5.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-3)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-9)" "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (8.36e-3)" "unprognostic (1.46e-1)" 0.3 0.2 0.1 0.0 0.8 0.2 0.4 1.7 0.8 1.0 87.7 0.0 0.0 2.0 0.0 0.1 0.9 0.4 1.1 1.7 0.0 0.3 1253.1 2.5 0.0 0.0 0.0 1.8 0.5 10.1 0.8 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.2 0.4 0.1 0.2 0.0 0.7 0.0 0.0 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 208.2 0.1 0.8 0.5 0.1 0.0 1.6 0.0 0.0 20.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 2.4 16.5 0.0 0.7 0.0 0.0 3.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.1 0.1 0.0 0.2 7.2 0.2 13.9 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.5 0.1 0.0 0.1 0.8 1.7 0.8 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 11.3 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.7 1.6 0.0 0.1 2.3 0.0 0.0 1.3 0.0 3.9 283.7 0.1 0.0 0.9 0.0 0.0 6.3 0.0 0.0 1.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.5 3.4 0.0 0.0 SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 418.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 165.1;Fibroblasts: 162.1;Pancreatic endocrine cells: 231.8;Smooth muscle cells: 239.3;Syncytiotrophoblasts: 651.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 20 "NK-cells: 9.5" "Cell line enhanced" "Detected in many" "BJ: 3483.8;HUVEC TERT2: 4014.7;LHCN-M2: 3874.5;TIME: 10032.6;U-138 MG: 4609.6;U-251 MG: 4256.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA050039, CAB068501" Uncertain Approved Cytosol "Secreted to blood" No No 142000000 13000000 "Cluster 22: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB068501: AB_1642775, HPA050039: AB_2680997" "unprognostic (5.02e-2)" "prognostic unfavorable (5.01e-4)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.10e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (2.84e-5)" "unprognostic (6.80e-3)" "prognostic unfavorable (4.41e-6)" "unprognostic (2.33e-1)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.88e-8)" "prognostic unfavorable (3.27e-6)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.51e-4)" 215.5 75.3 3.1 91.6 3.4 1.7 56.2 5.2 12.8 62.1 5.0 31.7 7.4 31.1 1.0 16.4 41.3 360.3 136.0 3.9 6.6 166.2 345.8 260.2 21.3 6.4 3.7 105.6 135.1 11.8 12.3 418.0 4.5 37.8 5.4 4.9 10.6 8.0 17.8 21.2 13.1 74.3 4.8 13.8 30.3 5.5 12.7 6.7 59.5 4.3 3.5 359.9 19.2 6.0 77.3 64.4 1.2 5.1 766.6 1511.0 89.3 3483.8 654.6 1717.6 1487.4 9.4 5.5 2.7 812.6 1117.9 2367.3 18.1 0.4 269.4 1756.2 4.3 0.7 1.1 5.2 61.4 1532.6 0.2 3.8 596.1 106.9 2641.4 1374.8 928.5 4014.7 0.2 6.4 2.5 3874.5 0.4 0.6 2.2 18.2 1.3 41.7 0.6 6.1 4.8 5.1 30.3 1.0 0.8 286.3 77.2 8.3 410.9 3.3 9.9 10032.6 4609.6 204.0 1593.8 4256.0 0.6 2.9 4.2 1150.5 2.4 45.9 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 9.5 0.0 0.3 0.0 0.8 3.1 3.4 5.2 12.8 3.9 6.6 6.4 3.7 4.5 4.8 12.7 6.0 35.8 0.0 7.7 0.0 1.1 40.0 43.7 97.4 14.2 0.3 0.3 2.3 2.5 4.3 11.0 5.5 0.0 56.0 1.0 0.4 0.0 65.1 0.0 4.7 53.8 165.1 5.3 0.0 0.5 4.5 75.1 162.1 0.5 3.2 10.2 12.4 40.4 112.3 15.9 0.0 0.3 0.2 8.2 4.6 9.6 1.1 17.7 11.1 7.2 5.6 1.1 0.7 0.0 0.0 0.0 231.8 0.0 12.0 3.6 9.7 0.1 0.0 8.2 0.3 39.5 55.4 239.3 0.0 0.1 9.0 24.7 651.7 2.3 2.1 0.5 8.1 SERPINE2 "GDN, nexin, PI7, PN1, PNI" ENSG00000135919 "Serpin family E member 2" P07093 2 223975045-224039318 "Plasma proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein, Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 1091.9" "Cell type enriched" "Detected in many" 8 "Granulosa cells: 4466.0" "Cancer enriched" "Detected in all" 9 "melanoma: 271.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 12.9;naive CD8 T-cell: 6.8;NK-cell: 23.2" "Group enriched" "Detected in many" 15 "NK-cells: 23.2;T-cells: 12.9" "Cell line enhanced" "Detected in many" "BJ: 1492.9;fHDF/TERT166: 6425.1;SK-MEL-30: 2966.9;WM-115: 2183.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000277 Approved "Golgi apparatus" "Secreted in female reproductive system" NA NA 910000 "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "HPA000277: " "unprognostic (1.73e-1)" "unprognostic (7.08e-3)" "unprognostic (8.49e-2)" "unprognostic (7.78e-3)" "unprognostic (2.57e-3)" "unprognostic (5.57e-2)" "unprognostic (1.49e-2)" "unprognostic (7.43e-3)" "unprognostic (4.41e-1)" "unprognostic (7.12e-2)" "unprognostic (7.56e-3)" "unprognostic (2.40e-1)" "unprognostic (1.97e-3)" "unprognostic (1.23e-2)" "unprognostic (1.31e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.48e-5)" 28.0 19.8 120.3 75.7 125.9 6.5 14.3 128.6 158.7 28.1 71.1 22.7 28.2 17.4 5.6 36.2 20.8 46.0 100.0 115.9 145.9 39.3 10.8 14.5 30.9 158.1 152.6 145.6 8.5 3.4 8.7 1091.9 134.4 26.4 21.8 5.4 12.6 7.5 6.6 11.2 27.0 119.6 141.1 30.9 8.9 57.6 146.4 17.0 26.1 10.8 44.0 146.9 27.6 132.0 3.1 83.8 29.4 32.6 1172.5 438.7 4.4 1492.9 851.5 118.1 112.7 4.8 7.0 0.4 32.5 6425.1 188.0 5.0 3.5 102.5 101.0 0.6 26.8 16.6 49.9 22.7 57.7 12.8 1.5 128.3 68.5 342.0 505.6 304.6 9.0 5.4 0.5 1.9 412.1 4.5 2.3 3.9 56.2 31.8 92.3 10.3 25.2 64.5 1100.2 97.5 43.0 7.1 284.4 0.5 2966.9 385.2 1.2 6.4 1056.5 692.5 96.6 214.4 72.7 6.3 13.3 0.8 443.5 11.1 2183.6 0.0 0.0 0.0 0.7 0.0 0.5 0.8 0.6 0.6 0.0 1.2 12.9 6.8 0.5 23.2 0.0 0.2 0.7 2.7 120.3 125.9 128.6 158.7 115.9 145.9 158.1 152.6 134.4 141.1 146.4 132.0 13.5 0.0 1.1 233.1 3.1 23.3 16.0 132.2 351.7 5.3 7.9 8.5 5.3 0.0 4.6 7.3 0.0 106.1 11.3 19.5 11.7 13.0 2.6 5.3 17.7 20.9 24.0 23.1 86.1 33.2 524.3 556.7 5.6 5.9 2.5 4466.0 23.2 0.0 45.5 0.0 11.4 4.7 0.0 0.8 26.9 9.9 401.4 9.7 142.3 23.4 3.5 2.5 2.1 199.6 13.5 22.1 14.9 98.9 5.6 27.2 2.0 146.2 1.7 3.5 13.1 5.2 146.6 4.2 70.9 34.8 14.5 133.9 10.7 18.9 3.1 7.2 SERPINE3 ENSG00000253309 "Serpin family E member 3" A8MV23 13 51335773-51364735 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;pancreas: 1.3;retina: 1.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.6;Early spermatids: 2.6;Excitatory neurons: 2.3;Inhibitory neurons: 1.9;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 2.5;Spermatocytes: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.3" "HPA051904, HPA055804" Uncertain "Secreted in other tissues" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA051904: AB_2681659, HPA055804: AB_2682928" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (9.66e-2)" "unprognostic (3.89e-2)" "unprognostic (5.52e-2)" "unprognostic (8.54e-3)" "unprognostic (2.67e-3)" "unprognostic (2.73e-1)" "unprognostic (1.87e-2)" "unprognostic (1.99e-3)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (3.94e-6)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.31e-2)" 0.7 0.1 0.3 0.2 0.6 0.0 0.1 1.7 0.9 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.7 0.2 0.1 0.2 0.0 0.3 0.5 0.3 0.1 1.3 0.0 0.1 0.0 0.6 0.1 0.0 1.8 0.1 0.0 0.0 0.8 0.7 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.5 0.0 0.0 0.0 0.3 0.6 0.8 0.2 0.5 0.0 0.3 0.1 0.2 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 1.7 0.9 0.7 0.2 0.5 0.3 0.6 0.2 0.3 0.8 0.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.2 0.2 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.1 2.9 0.0 0.9 0.0 0.0 0.5 0.7 0.0 0.0 SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1875.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 697.8;Cytotrophoblasts: 795.6;Fibroblasts: 951.9;Hepatocytes: 765.0;Leydig cells: 1818.0;Peritubular cells: 1045.7" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enhanced" "Detected in many" "hippocampal formation: 85.4" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1454.4" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1454.4" "Group enriched" "Detected in many" 4 "ASC diff: 1232.0;ASC TERT1: 956.3;Hep G2: 606.0;HHSteC: 410.6;HSkMC: 1313.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" NA NA 9290000000 44000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" 535.5 57.5 5.7 124.2 9.6 11.9 490.2 17.9 28.0 558.7 1875.2 131.3 41.9 358.2 90.2 109.3 557.4 559.7 376.5 85.4 1.1 35.1 974.8 158.9 133.5 0.1 5.1 408.3 207.6 11.2 62.4 311.6 1.3 202.8 52.0 61.4 124.6 105.8 434.8 162.9 131.7 221.7 2.8 133.2 124.7 277.7 25.4 106.2 193.1 465.5 117.7 323.4 273.5 7.0 0.5 3.7 2.8 2.0 1232.0 956.3 20.4 56.8 49.8 0.6 0.0 9.7 0.5 2.3 1.9 71.8 0.3 3.2 86.0 4.4 0.0 0.6 46.0 1.0 1.2 606.0 410.6 1.1 1.1 1313.4 6.9 0.9 1.1 11.4 0.6 4.2 117.5 0.4 63.2 0.2 7.0 7.2 30.7 0.3 1.0 2.9 219.9 1.6 0.1 6.0 1.9 42.2 0.7 0.7 57.0 3.4 6.7 184.2 2.0 0.5 17.6 14.1 1.2 0.7 2.4 28.1 1.7 0.6 0.8 0.1 12.0 1.1 0.6 4.4 0.4 9.0 0.7 0.9 79.8 5.2 2.0 5.5 1.7 1.3 0.2 1454.4 0.8 14.2 5.7 9.6 17.9 28.0 85.4 1.1 0.1 5.1 1.3 2.8 25.4 7.0 59.0 3.2 10.4 0.3 10.8 95.0 238.0 697.8 27.9 59.3 6.7 71.2 12.1 11.5 167.7 1.8 223.1 795.6 226.1 0.0 0.0 0.3 11.2 12.5 372.4 26.2 0.0 19.2 5.3 24.5 98.7 951.9 11.2 6.7 22.9 1.7 28.2 765.0 151.6 3.3 2.6 0.0 366.2 60.4 262.6 53.0 1818.0 79.0 108.5 9.4 79.0 11.6 1.0 0.5 2.0 6.8 0.1 1045.7 7.0 155.5 0.2 27.3 105.5 39.1 19.7 193.3 202.8 12.7 8.7 4.5 78.6 534.8 14.3 10.2 0.3 47.7 SERPINF2 "A2AP, AAP, ALPHA-2-PI, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1578.5" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1007.7" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.7" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.7" "Cell line enriched" "Detected in some" 24 "Hep G2: 145.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001885, CAB024863" Approved "Secreted to blood" NA NA 11900 61000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB024863: , HPA001885: AB_1079922" "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" 11.6 2.0 1.4 4.3 1.5 0.4 18.3 1.2 2.2 7.1 11.1 4.2 0.7 8.7 101.4 3.0 19.6 0.7 2.5 2.0 1.4 74.1 1578.5 12.9 3.0 1.6 1.6 7.7 9.2 0.1 1.9 0.8 1.7 21.4 0.5 0.5 6.1 32.6 4.3 5.5 11.6 1.8 1.3 7.1 3.7 12.5 1.8 2.6 7.9 0.4 3.5 7.3 5.8 2.2 1.8 6.1 0.0 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.3 0.9 0.0 0.3 0.9 0.0 3.3 0.0 0.0 0.0 0.1 0.9 145.9 1.1 0.8 0.1 1.6 1.2 0.0 0.7 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.7 0.1 0.3 0.3 0.1 0.9 1.3 0.0 0.3 0.0 0.2 0.6 0.0 1.1 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.9 1.4 0.0 0.8 0.0 0.5 0.0 0.0 10.7 0.5 0.0 0.0 0.0 1.2 0.0 44.7 0.0 1.2 1.4 1.5 1.2 2.2 2.0 1.4 1.6 1.6 1.7 1.3 1.8 2.2 1.6 3.2 19.6 0.3 5.3 1.5 4.9 10.3 8.0 0.2 20.5 8.8 0.7 27.1 7.0 1.8 6.2 0.2 32.1 0.7 9.8 0.0 0.6 0.1 2.7 3.4 4.2 23.6 1.6 4.9 0.3 2.7 0.0 0.3 1.3 0.3 14.6 1007.7 7.7 0.0 1.9 2.1 12.2 32.2 20.1 0.8 33.8 8.2 1.8 1.0 10.9 0.1 0.0 1.0 0.7 3.8 2.7 26.7 3.2 2.8 2.2 87.5 4.4 0.4 0.0 1.3 1.2 0.4 0.5 1.3 1.6 0.3 2.6 0.0 3.3 1.8 SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2622.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 726.4;Ductal cells: 604.0;Fibroblasts: 793.6;Hepatocytes: 2530.0;Leydig cells: 735.3" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.2;plasmacytoid DC: 60.6" "Group enriched" "Detected in many" 243 "dendritic cells: 60.6;granulocytes: 65.2;monocytes: 25.7" "Group enriched" "Detected in many" 6 "ASC diff: 1372.2;ASC TERT1: 694.9;HSkMC: 1159.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 194.1" "CAB026161, HPA048738" Supported "Secreted to blood" NA NA 28000000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" 971.5 144.2 27.4 90.0 27.5 10.9 733.0 27.1 36.0 629.4 53.4 358.7 52.0 616.7 163.3 162.0 793.2 533.0 547.1 26.2 34.8 337.3 2622.4 785.0 147.6 67.4 34.7 918.3 267.5 55.2 138.2 198.9 34.2 329.3 97.0 34.5 250.5 258.1 151.8 293.5 283.5 226.8 42.3 240.7 344.8 50.6 37.2 36.1 338.2 173.4 64.4 555.9 519.8 35.1 0.0 0.0 48.2 0.0 1372.2 694.9 7.3 74.2 57.0 16.8 30.7 2.5 0.0 0.0 96.7 42.1 0.0 0.0 0.4 4.7 9.4 0.0 0.1 33.7 0.0 1.7 170.3 0.9 5.4 1159.0 15.5 5.7 0.2 6.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 1.3 46.6 0.0 0.0 4.3 4.0 0.7 7.4 0.0 0.2 14.4 0.3 0.0 0.9 41.8 0.2 3.3 0.0 0.8 21.2 0.7 0.0 0.2 0.4 0.6 0.2 0.5 0.0 0.0 18.3 0.3 0.0 25.7 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 65.2 0.2 11.5 60.6 0.0 5.7 27.4 27.5 27.1 36.0 26.2 34.8 67.4 34.7 34.2 42.3 37.2 35.1 162.1 118.6 110.8 5.5 8.0 75.8 61.2 7.1 24.5 0.8 24.2 57.7 28.7 726.4 57.5 158.2 0.0 37.1 15.3 0.0 43.0 604.0 4.8 76.0 297.4 150.5 0.0 69.2 3.6 44.0 93.4 793.6 8.6 69.6 7.6 8.3 260.5 2530.0 43.6 0.0 6.2 0.1 2.0 118.9 94.2 25.6 735.3 46.9 90.7 15.9 10.4 57.2 0.0 3.5 0.5 41.4 0.0 228.7 4.5 32.4 0.0 53.5 23.1 4.5 269.5 143.6 259.6 2.5 10.4 9.0 59.5 25.2 16.8 3.4 0.0 37.4 SERPINI1 PI12 ENSG00000163536 "Serpin family I member 1" Q99574 3 167735243-167825569 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 301.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 219.4;Excitatory neurons: 176.9;Inhibitory neurons: 228.8;Oligodendrocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 29.2;Karpas-707: 29.1;U-266/84: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001565, HPA056092" Enhanced Uncertain Cytosol "Secreted in brain" NA NA 750000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA001565: AB_1079924, HPA056092: AB_2683036" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-3)" "unprognostic (1.35e-1)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.61e-1)" "unprognostic (6.07e-3)" "unprognostic (2.18e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-3)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" 13.1 15.8 138.8 4.1 157.7 2.3 11.7 115.9 301.4 8.4 82.1 5.1 2.2 8.6 8.2 5.5 7.9 6.3 14.0 162.0 129.1 32.1 4.1 6.4 4.6 122.8 153.6 6.9 39.5 6.9 42.8 6.7 123.9 11.8 4.4 84.4 23.0 7.4 3.2 3.1 4.4 6.1 134.6 8.7 10.8 15.8 134.5 4.4 11.2 8.1 8.2 4.9 6.0 164.8 0.8 3.5 5.5 0.4 10.3 2.2 0.3 1.9 2.7 1.3 2.2 1.5 5.9 29.2 9.5 1.3 4.5 1.3 3.9 3.8 1.5 7.7 6.5 8.9 22.5 10.7 0.7 1.4 1.1 3.8 1.4 0.8 1.3 2.9 0.4 10.5 18.9 29.1 1.2 2.7 0.8 1.9 3.3 4.2 4.5 2.7 0.4 3.2 11.2 1.0 2.2 13.4 3.6 6.8 8.3 12.4 10.6 4.4 1.0 5.5 0.5 0.5 10.3 23.0 28.4 18.8 4.2 7.7 3.2 1.5 0.3 0.8 9.3 0.7 6.9 22.1 9.7 10.2 0.5 25.2 6.9 8.1 0.9 9.5 0.5 7.2 27.2 5.2 138.8 157.7 115.9 301.4 162.0 129.1 122.8 153.6 123.9 134.6 134.5 164.8 49.8 6.4 1.5 43.1 10.7 3.7 13.2 6.4 14.2 219.4 3.6 14.1 8.2 1.5 6.7 5.5 14.6 6.1 6.2 0.7 7.9 1.8 0.4 2.0 1.0 16.0 4.8 7.4 176.9 18.0 6.0 8.9 2.6 1.7 2.5 2.3 3.9 0.6 2.3 5.0 228.8 0.3 73.2 0.6 3.2 2.4 4.1 0.9 7.2 25.3 1.2 78.0 2.1 31.2 174.7 3.0 0.0 2.6 14.6 6.7 0.0 39.9 13.6 35.4 26.3 5.2 54.7 3.0 27.4 0.5 1.7 5.1 6.2 1.1 0.3 2.3 SERPINI2 "MEPI, PANCPIN, PI14, TSA2004" ENSG00000114204 "Serpin family I member 2" O75830 3 167441789-167479004 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 133 "pancreas: 1370.0" "Cell type enhanced" "Detected in some" "Astrocytes: 37.5;Exocrine glandular cells: 93.4;Respiratory ciliated cells: 22.9" "Cancer enriched" "Detected in some" 6 "pancreatic cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "THP-1: 9.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 8.7" "Secreted to digestive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 43: THP-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (1.88e-2)" "unprognostic (2.23e-3)" "unprognostic (1.14e-1)" "unprognostic (5.27e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "unprognostic (2.04e-1)" "unprognostic (3.13e-1)" "unprognostic (1.76e-5)" "unprognostic (5.35e-2)" "unprognostic (4.16e-2)" 0.1 0.1 3.7 0.0 2.9 0.4 0.1 4.4 1.5 0.2 10.2 0.1 1.0 0.2 0.2 0.2 3.9 0.0 0.5 2.5 3.7 0.2 0.0 1.0 0.1 9.6 7.7 0.5 1370.0 0.0 0.4 0.0 7.1 0.2 0.0 0.0 0.4 0.0 0.0 0.1 1.9 0.1 9.4 0.2 0.3 0.1 4.3 0.0 0.0 0.2 0.1 0.1 0.1 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 9.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.7 2.9 4.4 1.5 2.5 3.7 9.6 7.7 7.1 9.4 4.3 5.8 0.0 0.0 1.1 37.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 5.9 0.1 0.1 0.0 0.0 3.6 93.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 1.2 0.0 0.0 2.0 0.9 4.8 0.0 0.0 0.0 0.0 0.7 0.0 22.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2461.5;skin 1: 1219.1;vagina: 692.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7750.0;Basal prostatic cells: 2119.7;Squamous epithelial cells: 3587.1;Suprabasal keratinocytes: 10714.0;Urothelial cells: 2780.0" "Cancer enhanced" "Detected in all" "cervical cancer: 1510.8;head and neck cancer: 2526.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cell line enhanced" "Detected in many" "A-431: 770.8;HaCaT: 1181.6;HBEC3-KT: 1819.0;hTCEpi: 1196.7" "Low region specificity" "Detected in many" "CAB006268, HPA011105, CAB040552" Enhanced Supported Cytosol "Secreted in other tissues" NA Yes 29000000 "Cluster 34: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB006268: AB_425459, CAB040552: , HPA011105: AB_1844339" "unprognostic (5.70e-2)" "unprognostic (1.26e-1)" "unprognostic (8.37e-2)" "prognostic favorable (1.92e-4)" "unprognostic (1.26e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (1.71e-2)" "unprognostic (2.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (7.45e-6)" "unprognostic (7.90e-3)" "unprognostic (3.25e-1)" "unprognostic (8.12e-2)" "unprognostic (2.06e-2)" 3.1 0.8 1.9 11.6 1.8 2.0 29.1 1.8 9.5 350.2 0.4 95.4 48.8 8.0 0.7 2461.5 2.2 21.4 1.3 1.9 1.6 16.0 3.7 56.1 0.2 9.0 4.4 0.9 2.2 0.1 2.7 1.6 4.3 77.2 32.5 0.6 332.8 3.2 5.0 1219.1 40.8 3.3 1.2 0.9 66.6 0.7 5.2 22.1 2.0 0.1 147.9 167.6 692.0 2.3 770.8 126.9 0.1 1.1 0.3 0.1 37.2 0.5 0.0 0.1 0.3 46.6 393.6 6.7 32.2 0.2 0.6 1181.6 0.3 1819.0 0.0 183.4 5.4 0.9 119.6 138.4 0.1 0.4 1.4 0.4 1196.7 0.6 310.1 0.2 0.2 0.7 1.8 4.5 0.1 163.8 0.7 0.3 2.3 132.6 208.7 0.5 0.4 43.1 281.3 173.9 0.7 0.7 181.2 31.9 1.8 2.9 83.6 1.5 0.5 0.5 337.2 0.3 4.9 1.0 5.8 3.8 1.5 0.7 0.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 1.8 1.8 9.5 1.9 1.6 9.0 4.4 4.3 1.2 5.2 2.3 1.6 179.5 162.2 0.0 5.0 7750.0 2119.7 1374.7 1714.2 0.0 72.6 119.9 0.8 24.3 285.6 16.5 0.0 18.6 0.7 972.0 3.9 48.8 0.0 138.0 20.1 45.3 67.4 0.0 0.0 76.2 59.9 46.2 221.2 251.8 32.3 0.0 0.4 4.5 1.9 0.0 0.1 140.7 114.0 0.6 479.7 0.0 0.0 9.7 533.6 0.0 1.0 0.0 0.0 0.0 0.1 524.8 933.0 0.0 21.2 1030.2 318.5 0.6 158.2 0.0 0.0 0.7 55.2 0.0 0.6 3587.1 10714.0 6.0 23.4 0.1 292.4 2780.0 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 299.3;choroid plexus: 509.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 710.9;Breast myoepithelial cells: 1158.6;Cardiomyocytes: 266.3;Leydig cells: 578.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 3203.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" Yes No 1300000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: AB_2685376" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" 88.4 12.9 9.2 10.5 12.7 1.4 299.3 18.2 15.0 203.7 509.2 24.5 12.2 132.5 1.8 26.1 98.5 61.3 124.8 29.4 8.5 115.3 6.1 4.7 4.0 29.9 10.5 46.8 6.2 1.4 1.2 19.5 29.7 42.6 30.1 2.2 236.9 102.3 2.6 55.4 18.9 82.9 7.7 21.4 24.4 28.4 10.8 3.1 12.7 32.8 3.2 44.9 95.6 24.7 0.1 29.0 75.9 1.9 67.5 3.9 14.5 132.9 694.5 197.9 187.2 0.0 17.8 0.0 0.6 0.7 15.8 0.9 10.8 53.7 277.6 0.0 2.3 0.0 0.0 0.0 6.4 0.0 0.7 11.8 255.9 19.9 19.3 3203.5 6.2 0.2 0.0 0.0 3.7 0.0 0.0 0.2 205.8 0.1 0.3 0.0 15.7 0.0 422.6 0.0 4.1 18.5 5.5 0.0 41.5 264.7 0.1 2.1 1.9 0.1 19.6 0.2 18.3 0.0 0.0 0.0 0.2 0.0 279.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.7 18.2 15.0 29.4 8.5 29.9 10.5 29.7 7.7 10.8 24.7 8.4 0.0 0.0 2.0 1.2 11.2 134.0 1.4 147.4 1.8 710.9 1158.6 266.3 0.0 0.7 62.5 2.1 2.2 9.1 0.0 80.3 4.4 5.0 3.0 131.6 21.0 0.0 0.0 0.2 0.0 82.0 229.5 16.8 3.4 0.0 19.3 53.6 0.3 2.0 1.7 12.1 0.0 0.0 0.3 4.0 25.7 578.4 4.0 99.6 0.0 0.0 76.2 0.0 7.5 20.6 0.1 0.0 130.1 2.1 29.7 0.0 3.2 0.0 1.8 0.0 34.9 18.0 2.3 16.8 53.7 5.5 0.8 7.3 72.6 0.0 9.3 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SFRP5 SARP3 ENSG00000120057 "Secreted frizzled related protein 5" Q5T4F7 10 97766751-97771999 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 98.7;heart muscle: 78.7;intestine: 36.4;pancreas: 143.2" "Cell type enriched" "Detected in some" 7 "Cholangiocytes: 273.1" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 30.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "naive CD8 T-cell: 3.6" "Lineage enriched" "Detected in single" 4 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "A549: 2.5;CACO-2: 12.4;RPMI-8226: 4.5;SCLC-21H: 2.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 120.7" "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (2.63e-4)" "unprognostic (3.03e-3)" "unprognostic (6.74e-2)" "unprognostic (3.43e-2)" "unprognostic (9.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (3.19e-1)" "unprognostic (2.85e-1)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (4.51e-9)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (9.17e-2)" "unprognostic (1.62e-1)" 2.9 9.6 2.8 0.3 3.9 0.3 2.4 1.6 0.6 3.5 98.7 36.4 29.8 1.8 2.2 2.0 2.2 4.1 78.7 5.6 7.5 0.4 8.8 3.4 0.3 3.6 8.3 0.6 143.2 0.0 0.9 0.0 3.6 6.8 0.5 0.2 2.8 4.0 1.3 3.1 26.3 0.4 1.6 0.1 10.5 0.8 14.7 0.1 1.0 2.9 0.1 3.2 4.9 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 4.5 0.0 0.0 2.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.8 0.0 0.2 2.8 3.9 1.6 0.6 5.6 7.5 3.6 8.3 3.6 1.6 14.7 0.2 0.0 3.2 3.6 0.3 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 7.8 273.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.1 0.6 0.0 0.0 0.2 16.8 0.0 3.2 0.0 0.0 0.0 0.0 2.2 0.7 0.0 0.0 0.3 1.3 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.2 3.3 2.5 0.0 0.0 0.0 37.8 0.0 0.0 0.2 0.0 1.2 0.4 0.1 5.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 SFTA2 SFTPG ENSG00000196260 "Surfactant associated 2" Q6UW10 6 30931353-30955636 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 49.1;lung: 179.1" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 535.2;Alveolar cells type 2: 806.4" "Cancer enhanced" "Detected in many" "lung cancer: 121.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "CACO-2: 12.0;CAPAN-2: 5.5" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (5.82e-2)" "unprognostic (1.16e-1)" "unprognostic (7.20e-3)" "unprognostic (6.64e-2)" "unprognostic (3.12e-1)" "unprognostic (1.34e-1)" "unprognostic (6.37e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (1.16e-1)" "unprognostic (3.96e-4)" "unprognostic (8.84e-2)" "unprognostic (2.36e-2)" "unprognostic (5.39e-3)" "unprognostic (7.95e-2)" 0.2 0.2 0.5 0.1 0.6 0.0 0.3 0.5 0.9 4.7 0.5 0.1 0.0 0.4 0.0 49.1 0.6 0.8 0.2 0.5 0.5 6.1 0.4 179.1 0.2 0.6 0.6 0.4 4.4 0.3 0.1 0.2 0.6 0.2 0.0 0.1 4.1 0.1 0.6 0.1 0.2 0.1 0.6 0.3 7.9 1.7 0.5 0.1 2.0 0.1 0.2 0.2 21.6 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.5 0.9 0.5 0.5 0.6 0.6 0.6 0.6 0.5 0.6 0.2 535.2 806.4 0.0 1.0 0.1 0.1 0.0 0.0 0.5 0.9 0.3 0.0 140.2 111.8 53.3 0.0 0.1 0.0 0.0 3.9 22.7 3.8 76.1 2.5 2.1 0.0 0.0 0.0 35.6 0.0 0.8 13.7 23.0 12.6 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 13.7 0.3 1.3 0.0 0.0 0.1 2.8 0.0 0.0 0.1 94.2 0.0 0.4 0.5 0.3 0.0 0.8 8.1 0.1 0.0 1.1 0.4 7.5 1.7 2.8 0.0 0.0 1.7 0.1 0.1 1.1 SFTPA1 "COLEC4, SFTP1, SP-A, SP-A1" ENSG00000122852 "Surfactant protein A1" Q8IWL2 10 79610939-79615455 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1048 "lung: 7084.8" "Cell type enriched" "Detected in some" 11 "Alveolar cells type 2: 13480.7" "Cancer enriched" "Detected in some" 25 "lung cancer: 706.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 27 "plasmacytoid DC: 2.7" "Lineage enriched" "Detected in single" 27 "dendritic cells: 2.7" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 43.2" "CAB016793, HPA042638, HPA045752, HPA049368" Supported "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB016793: , HPA042638: AB_2678095, HPA045752: AB_2679442, HPA049368: AB_2680731" "unprognostic (5.83e-4)" "unprognostic (1.17e-1)" "unprognostic (3.38e-2)" "unprognostic (4.24e-1)" "unprognostic (3.47e-2)" "unprognostic (9.09e-2)" 0.5 6.7 0.1 2.6 0.1 0.0 0.5 0.3 0.3 0.9 0.0 0.3 0.0 0.1 0.0 0.2 0.2 0.0 0.8 0.2 0.0 0.2 0.9 7084.8 0.0 0.0 0.0 6.3 0.7 0.0 0.3 1.4 0.0 1.0 0.0 0.0 0.2 4.8 0.8 0.8 0.4 0.0 0.0 4.9 3.8 0.3 0.0 1.5 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.7 0.1 0.0 0.0 0.0 0.0 43.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 7.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.1 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 13480.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 183.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 454.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 SFTPA2 "COLEC5, SP-A2" ENSG00000185303 "Surfactant protein A2" Q8IWL1 10 79555852-79560407 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 404 "lung: 10798.8" "Cell type enriched" "Detected in some" 10 "Alveolar cells type 2: 16905.3" "Cancer enriched" "Detected in many" 21 "lung cancer: 863.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "BEWO: 7.3;NB-4: 8.3;RPMI-8226: 26.1;U-2197: 14.7" "CAB002439, HPA042638, HPA045752, HPA049368" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 19: Lung - Lung function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB002439: AB_564143, HPA042638: AB_2678095, HPA045752: AB_2679442, HPA049368: AB_2680731" "unprognostic (2.51e-1)" "unprognostic (4.87e-2)" "unprognostic (4.99e-2)" "unprognostic (4.38e-2)" "unprognostic (4.29e-2)" "unprognostic (1.05e-1)" "unprognostic (5.78e-2)" "unprognostic (5.08e-1)" "unprognostic (4.94e-2)" "unprognostic (1.68e-3)" "unprognostic (3.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (4.69e-3)" 0.7 12.1 0.4 4.6 0.6 0.0 1.0 3.1 0.9 1.4 0.0 1.4 0.0 0.2 0.1 0.4 0.2 0.0 1.1 0.5 0.4 0.4 1.1 10798.8 0.0 1.2 0.0 6.5 1.3 0.0 0.4 2.3 1.3 26.7 2.6 0.2 0.4 8.3 1.0 1.1 0.5 0.1 0.0 6.7 10.5 0.5 0.3 2.7 0.8 0.0 0.1 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 8.3 0.4 0.0 0.0 0.2 0.0 26.1 0.0 0.3 0.3 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.2 14.7 0.1 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.6 3.1 0.9 0.5 0.4 1.2 0.0 1.3 0.0 0.3 0.6 0.0 1593.0 16905.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 329.9 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.2 0.0 0.0 22.3 1.8 0.0 0.3 3.1 0.0 22.0 0.0 0.2 431.4 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.2 2.0 0.0 0.0 1.0 0.0 0.1 135.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.7 0.0 2.4 0.1 SFTPB "SFTP3, SP-B" ENSG00000168878 "Surfactant protein B" P07988 2 85657314-85668741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 32 "lung: 3566.0" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 15343.4" "Cancer enriched" "Detected in many" 5 "lung cancer: 1306.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 2.8;NB-4: 3.5;U-2197: 6.7;U-266/70: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002440, HPA034820, HPA062148" Enhanced "Secreted in other tissues" NA NA 80000000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "CAB002440: AB_564142, HPA034820: AB_2674347, HPA062148: AB_2684697" "unprognostic (6.46e-3)" "unprognostic (4.94e-2)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (2.25e-3)" "unprognostic (4.57e-3)" "unprognostic (8.57e-3)" "unprognostic (6.45e-3)" "unprognostic (1.13e-1)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (2.99e-6)" "unprognostic (2.37e-1)" "unprognostic (1.09e-1)" "unprognostic (7.90e-2)" "unprognostic (4.38e-2)" 0.8 4.4 1.5 2.2 1.4 0.4 0.5 1.7 3.0 0.5 1.1 0.5 0.3 0.2 0.7 0.4 0.3 0.2 1.4 1.3 2.1 2.1 1.2 3566.0 0.3 1.4 1.1 11.0 0.9 0.2 5.4 1.5 1.5 1.2 0.4 2.9 0.5 2.0 1.2 0.8 0.7 0.1 0.8 4.1 5.1 0.4 1.4 0.3 113.1 0.3 0.2 0.2 0.4 1.5 0.1 0.2 0.2 0.5 0.3 0.5 2.8 0.2 0.2 0.1 0.0 0.3 0.6 0.0 0.2 0.0 0.3 2.0 0.2 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.1 0.1 1.4 0.0 0.3 0.2 0.1 0.5 0.0 0.4 0.3 0.4 0.1 0.3 1.1 3.5 1.6 0.5 0.4 1.3 0.2 0.3 0.2 0.3 0.4 0.3 0.0 0.4 0.2 0.3 0.3 0.3 0.0 0.2 0.6 6.7 0.1 2.4 0.6 0.2 0.6 0.5 0.1 0.3 0.6 0.2 0.2 1.1 0.1 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.6 0.2 0.7 0.2 0.4 0.4 1.5 1.4 1.7 3.0 1.3 2.1 1.4 1.1 1.5 0.8 1.4 1.5 0.0 3650.6 15343.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.5 0.0 1930.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 14.4 0.0 0.0 0.2 0.2 0.0 26.9 0.0 0.0 262.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.0 0.3 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 185.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 36.5 0.0 0.0 0.2 SFTPC "BRICD6, PSP-C, SFTP2, SMDP2, SP-C" ENSG00000168484 "Surfactant protein C" P11686 8 22156913-22164479 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 795 "lung: 18462.2" "Cell type enriched" "Detected in some" 12 "Alveolar cells type 2: 107013.9" "Cancer enriched" "Detected in some" 218 "lung cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 9.5;NB-4: 12.4;SCLC-21H: 5.1;U-2197: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010928 Enhanced "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA010928: AB_1857425" "unprognostic (1.84e-1)" "unprognostic (1.96e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.97e-1)" "unprognostic (4.97e-2)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-2)" 2.6 23.2 10.3 10.3 12.1 0.0 0.9 10.8 15.8 1.6 8.3 1.3 0.0 0.4 0.3 0.9 0.4 0.0 2.8 10.2 10.6 1.0 2.8 18462.2 0.0 11.9 11.2 21.5 1.7 0.0 1.1 4.7 10.8 3.0 0.0 0.0 0.8 8.9 2.0 3.1 2.3 0.0 10.3 14.0 6.4 2.8 11.4 0.0 4.3 0.1 0.2 0.1 0.9 15.3 0.0 0.1 0.0 0.0 0.5 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 12.4 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 5.1 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.1 0.1 24.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 12.1 10.8 15.8 10.2 10.6 11.9 11.2 10.8 10.3 11.4 15.3 0.0 8535.2 107013.9 0.7 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 1416.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 67.8 0.0 0.0 0.9 0.0 0.0 174.6 0.0 0.0 986.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 30.4 0.0 106.6 23.2 0.0 0.0 0.0 0.0 0.5 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 339.6 0.0 6.6 0.0 0.3 0.1 0.1 0.0 0.6 0.0 163.4 0.4 0.0 0.1 SFTPD "COLEC7, SFTP4, SP-D" ENSG00000133661 "Surfactant protein D" P35247 10 79937467-79982614 "Predicted secreted proteins" "Gaseous exchange, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "lung: 507.9" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 2: 1863.1" "Cancer enriched" "Detected in many" 16 "lung cancer: 106.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 10.0;non-classical monocyte: 36.3" "Lineage enriched" "Detected in many" 18 "monocytes: 36.3" "Cell line enhanced" "Detected in some" "BEWO: 1.1;HaCaT: 1.0;hTCEpi: 3.2;MCF7: 1.3;U-2197: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB004578, HPA044582, HPA056768" Enhanced "Secreted in other tissues" NA NA 8200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "CAB004578: AB_628276, HPA044582: AB_2679004, HPA056768: AB_2683232" "unprognostic (3.81e-5)" "unprognostic (7.00e-2)" "unprognostic (1.19e-2)" "unprognostic (1.41e-2)" "unprognostic (4.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.66e-3)" "unprognostic (6.83e-2)" "unprognostic (3.85e-1)" "unprognostic (2.23e-1)" "unprognostic (5.29e-2)" "unprognostic (2.57e-1)" "unprognostic (4.70e-2)" "unprognostic (2.57e-2)" "unprognostic (2.38e-1)" "unprognostic (1.45e-1)" "unprognostic (8.86e-2)" 1.1 1.8 2.2 0.4 2.4 19.7 0.9 1.7 2.5 1.3 2.3 1.0 0.1 0.5 1.3 1.8 1.8 0.9 1.1 2.2 2.4 1.6 1.0 507.9 0.0 1.7 2.0 1.1 4.2 2.0 3.4 0.7 1.8 1.4 0.1 0.3 1.0 1.2 0.2 5.0 0.4 0.4 1.4 0.6 1.1 1.3 2.6 0.5 5.8 0.2 0.2 0.3 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.8 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 10.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.9 2.2 2.4 1.7 2.5 2.2 2.4 1.7 2.0 1.8 1.4 2.6 1.7 0.3 439.1 1863.1 1.0 0.2 0.9 1.3 7.8 1.2 1.7 1.4 1.8 0.7 0.0 38.0 5.5 0.0 0.1 0.0 0.0 1.9 1.4 7.4 0.6 0.1 1.5 0.0 0.0 4.9 5.8 3.0 4.4 0.0 0.9 20.2 1.6 0.4 0.7 0.1 0.0 3.5 0.0 0.0 0.0 2.7 12.2 1.2 2.9 0.0 1.9 0.6 2.8 0.0 0.0 0.6 2.0 0.1 0.4 0.0 0.8 0.0 0.2 9.6 0.5 0.0 1.8 0.4 0.4 0.3 0.6 1.8 0.1 4.3 0.1 0.1 0.6 SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 63.4" "Cell type enhanced" "Detected in some" "Early spermatids: 51.6;Late spermatids: 124.5;Proximal enterocytes: 31.1" "Cancer enriched" "Detected in some" 28 "liver cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.4;Hep G2: 3.0;HSkMC: 4.3" "Not detected" "Not detected" "Secreted to blood" NA NA 9100000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.35e-3)" "unprognostic (6.47e-2)" "unprognostic (5.65e-2)" "unprognostic (2.35e-1)" "unprognostic (8.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.50e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.32e-3)" "unprognostic (3.58e-3)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (7.83e-3)" "unprognostic (4.35e-1)" "unprognostic (5.50e-3)" "unprognostic (1.06e-1)" 0.7 1.3 1.8 0.0 1.8 0.1 0.4 1.7 2.0 0.7 1.9 0.3 5.3 0.5 0.9 0.2 0.6 0.3 0.6 1.9 1.8 3.5 63.4 0.3 0.1 1.8 1.8 0.7 0.4 0.5 0.7 0.3 1.9 0.5 0.2 0.9 0.2 0.4 0.8 0.1 7.1 0.2 1.7 0.4 0.3 12.4 1.7 0.2 0.8 0.7 0.1 0.3 0.2 1.8 0.1 2.4 2.4 0.3 4.4 2.0 0.1 0.6 0.9 0.9 0.5 0.9 0.3 0.0 0.5 0.8 1.2 0.3 0.1 0.1 0.5 0.1 0.3 0.0 0.6 3.0 1.4 0.0 0.1 4.3 0.3 1.6 0.8 0.8 0.1 0.0 0.2 0.1 0.2 0.5 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.3 0.3 0.1 0.3 1.8 0.0 0.2 0.8 0.4 0.0 0.8 0.4 0.0 0.0 0.2 0.3 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.7 2.0 1.9 1.8 1.8 1.8 1.9 1.7 1.7 1.8 0.2 0.0 0.0 0.7 0.5 0.0 0.3 0.1 0.0 0.4 0.5 0.6 0.5 0.0 0.2 0.0 0.0 0.4 0.0 0.2 5.9 0.5 51.6 0.4 0.6 0.1 0.0 0.0 1.0 0.2 0.1 0.4 0.0 0.2 0.0 0.6 1.1 13.8 0.3 0.0 0.9 1.3 2.0 0.8 0.0 124.5 0.9 0.5 0.0 0.0 0.0 2.4 0.0 0.5 0.6 0.1 1.3 0.7 0.0 0.3 31.1 12.8 0.4 1.3 6.6 0.2 0.3 7.2 0.8 0.0 0.0 0.3 0.1 1.1 0.5 0.3 SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.9;Alveolar cells type 2: 23.4;Endothelial cells: 64.4;Hepatic stellate cells: 85.3;Kupffer cells: 26.7;Late spermatids: 23.0;Microglial cells: 26.2;Spermatocytes: 30.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 49.1;TIME: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" 23.4 9.8 9.4 3.3 8.8 1.2 20.9 7.7 10.6 13.2 7.4 7.4 3.4 12.1 4.3 5.0 12.5 6.9 22.7 8.3 8.3 10.5 5.8 20.6 3.9 8.4 9.1 7.6 3.0 4.9 3.7 16.5 8.8 8.1 4.2 0.6 5.4 4.2 7.1 6.4 8.9 8.0 8.1 21.4 5.5 22.2 10.2 2.6 22.1 11.3 2.3 9.7 9.9 8.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 4.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 49.1 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.5 0.0 1.0 13.6 0.0 0.3 1.4 0.0 0.1 0.2 0.1 0.0 1.0 0.0 0.5 0.3 0.2 1.5 1.5 1.1 0.9 0.6 0.6 0.1 0.9 0.8 0.9 2.4 1.7 1.1 4.0 0.0 0.5 9.4 8.8 7.7 10.6 8.3 8.3 8.4 9.1 8.8 8.1 10.2 8.0 56.9 0.0 23.4 3.9 0.3 3.3 0.4 0.3 1.2 0.1 0.4 1.3 4.4 1.5 1.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 13.0 0.4 0.3 64.4 0.0 2.7 0.3 0.0 0.0 6.7 0.0 0.5 3.8 2.1 85.3 3.4 1.4 0.0 0.3 0.0 0.0 26.7 6.6 23.0 1.5 2.0 0.0 26.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 3.7 0.7 0.0 0.1 0.0 0.4 0.0 3.3 2.2 30.6 13.0 0.3 1.6 0.1 0.7 0.3 0.0 0.3 SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 106.7" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 76.0;granulocytes: 55.0;Syncytiotrophoblasts: 188.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.9;memory B-cell: 7.2;naive B-cell: 4.5;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 13 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Cell line enriched" "Detected in some" 7 "HMC-1: 500.7" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA008945: , HPA009084: AB_1079967, HPA018198: AB_1856868" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (9.31e-3)" "unprognostic (8.46e-4)" "unprognostic (2.91e-1)" "unprognostic (2.02e-2)" "unprognostic (2.64e-1)" "unprognostic (8.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.15e-2)" "unprognostic (4.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.57e-3)" 0.6 0.1 0.2 3.0 0.3 0.5 0.7 0.4 0.3 1.6 0.1 2.2 2.2 1.5 1.0 2.5 0.3 2.5 0.4 0.2 0.0 0.1 0.1 4.3 3.8 0.1 0.1 0.1 0.3 0.1 0.0 106.7 0.2 1.0 3.1 0.4 0.5 0.7 0.5 0.5 3.3 1.3 0.0 1.7 2.6 0.3 0.2 0.7 0.0 0.6 4.2 1.8 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 1.2 500.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 19.1 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.9 0.2 4.9 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 1.6 4.5 0.0 0.0 0.2 0.6 0.0 11.0 0.0 0.4 0.2 0.3 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.2 0.5 0.0 0.0 1.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 5.2 0.7 0.0 0.0 55.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.5 0.0 0.0 0.0 SIRPD "dJ576H24.4, PTPNS1L2" ENSG00000125900 "Signal regulatory protein delta" Q9H106 20 1534251-1557705 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 57.8" "Group enriched" "Detected in some" 118 "Early spermatids: 427.6;Late spermatids: 522.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "neutrophil: 37.2" "Group enriched" "Detected in many" 4 "granulocytes: 37.2;monocytes: 21.0" "Cell line enhanced" "Detected in some" "HL-60: 1.5;HMC-1: 1.9;NB-4: 2.6;THP-1: 5.6;U-937: 1.2" "Not detected" "Not detected" HPA042663 Enhanced "Secreted in male reproductive system" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 36: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "HPA042663: AB_2678102" "unprognostic (4.91e-2)" "unprognostic (1.51e-2)" "unprognostic (3.01e-2)" "unprognostic (4.47e-1)" "unprognostic (2.49e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (2.79e-1)" "unprognostic (3.66e-8)" "unprognostic (2.14e-1)" "unprognostic (3.32e-2)" "unprognostic (9.57e-3)" "unprognostic (2.44e-2)" 0.2 0.1 0.2 2.8 0.1 2.7 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.4 0.1 0.1 0.1 0.1 0.2 1.9 1.1 0.3 0.2 0.3 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.1 1.5 0.1 57.8 0.1 0.0 0.0 0.0 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.9 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 21.0 21.5 0.1 13.5 0.2 0.1 0.1 0.2 6.8 0.0 0.1 0.0 37.2 0.0 6.1 4.3 0.3 6.6 0.2 0.1 0.0 0.3 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 427.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 4.0 0.0 522.7 3.4 2.2 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647295 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 76.6" "Cell type enhanced" "Detected in some" "B-cells: 29.8;Melanocytes: 14.2;monocytes: 22.9;Plasma cells: 49.2;T-cells: 35.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 66.3" "Group enriched" "Detected in many" 10 "B-cells: 22.7;T-cells: 66.3" "Cell line enriched" "Detected in some" 104 "HDLM-2: 195.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" NA NA 350000 "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" 1.1 0.5 0.0 13.6 0.0 6.6 1.6 0.0 0.1 1.1 0.3 2.6 3.7 0.4 0.1 1.4 0.4 2.3 1.1 0.0 0.0 0.9 0.9 2.1 21.6 0.3 0.0 0.4 0.3 0.1 0.1 3.0 0.1 0.6 3.0 0.0 1.7 0.3 0.3 0.7 3.9 0.9 0.1 6.7 3.9 0.2 0.1 76.6 0.6 0.0 19.1 8.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 195.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.4 0.0 1.8 0.0 0.1 0.2 0.0 10.7 0.0 66.3 16.5 46.3 33.0 0.3 22.7 17.5 4.4 0.6 0.0 0.1 4.4 61.7 9.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 1.4 0.0 5.2 0.0 29.8 2.0 0.1 0.0 0.0 0.0 0.7 0.3 0.3 0.0 0.6 1.8 0.0 0.0 4.8 0.0 0.0 0.0 4.1 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 1.2 0.5 0.0 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.8 10.7 8.5 0.0 5.2 14.2 1.0 22.9 0.0 0.0 0.5 0.1 0.0 0.0 0.0 49.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.8 0.1 0.1 0.0 1.7 0.1 35.6 0.0 0.1 0.1 SLIT1 "MEGF4, SLIL1, Slit-1, SLIT3" ENSG00000187122 "Slit guidance ligand 1" O75093 10 96998038-97185959 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 32.5;pituitary gland: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 27.0;Excitatory neurons: 96.2;Inhibitory neurons: 34.6;Late spermatids: 25.5;Oligodendrocyte precursor cells: 25.1" "Group enriched" "Detected in many" 4 "glioma: 9.2;thyroid cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "JURKAT: 23.2;MOLT-4: 81.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006879 Approved "Plasma membrane" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA006879: AB_1078197" "unprognostic (2.72e-1)" "unprognostic (2.25e-2)" "unprognostic (5.67e-3)" "unprognostic (1.43e-5)" "unprognostic (8.40e-2)" "unprognostic (2.60e-3)" "unprognostic (4.57e-2)" "unprognostic (1.81e-2)" "unprognostic (3.53e-1)" "unprognostic (6.06e-2)" "unprognostic (2.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.66e-1)" "unprognostic (2.18e-1)" "unprognostic (1.21e-1)" "unprognostic (4.39e-3)" 0.4 0.1 28.6 0.2 32.5 0.2 0.1 0.0 29.8 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.1 28.7 5.2 0.1 0.1 0.2 0.1 0.0 2.1 0.1 0.6 0.1 13.5 0.0 0.0 0.3 0.1 0.8 0.1 0.0 0.1 0.0 0.2 0.1 1.6 0.3 0.3 1.8 14.1 2.4 2.5 0.0 0.1 0.1 0.1 7.4 0.0 0.1 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.1 0.3 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 23.2 0.0 0.6 0.0 0.2 81.0 0.3 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 4.9 2.1 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.1 1.7 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 28.6 32.5 0.0 29.8 28.7 5.2 0.0 2.1 0.0 1.6 14.1 7.4 0.2 0.0 0.0 6.5 0.5 0.0 0.1 0.0 0.0 3.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 27.0 0.5 0.1 0.1 1.8 0.0 96.2 0.0 0.0 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.5 0.0 34.6 0.0 0.0 0.3 0.0 25.5 0.0 0.3 0.0 2.8 0.2 0.1 0.0 25.1 3.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.5 0.2 0.0 0.1 0.2 3.4 2.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SLITRK1 "KIAA1910, LRRC12" ENSG00000178235 "SLIT and NTRK like family member 1" Q96PX8 13 83877205-83882474 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 13.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 15.3;Excitatory neurons: 18.4;Inhibitory neurons: 14.0;Oligodendrocyte precursor cells: 25.1;Oligodendrocytes: 14.3" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 3.0;AF22: 1.2;LHCN-M2: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074835 Enhanced "Secreted in brain" NA NA 330000 "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "HPA074835: " "unprognostic (2.29e-1)" "unprognostic (4.32e-1)" "unprognostic (4.71e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (7.95e-2)" 0.0 0.1 5.6 0.0 11.0 0.0 0.0 0.0 13.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 2.4 0.0 0.0 0.0 0.0 1.2 0.2 0.0 1.1 0.0 1.9 0.0 0.9 0.0 0.0 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.0 9.6 3.0 0.0 1.2 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 11.0 0.0 13.2 10.0 2.4 1.2 0.2 0.9 0.0 4.5 9.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 15.3 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 25.1 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLPI "ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4" ENSG00000124107 "Secretory leukocyte peptidase inhibitor" P03973 20 45252239-45254564 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 27919.2;salivary gland: 14140.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 4134.5;Basal respiratory cells: 18759.4;Club cells: 20435.8;Respiratory ciliated cells: 8096.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 79 "neutrophil: 321.8" "Lineage enriched" "Detected in many" 79 "granulocytes: 321.8" "Cell line enhanced" "Detected in many" "EFO-21: 1719.5;hTCEpi: 2037.1;OE19: 767.9;SiHa: 622.1;THP-1: 531.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002303, HPA027774" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 26400000 9600000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "CAB002303: AB_564008, HPA027774: AB_10602405" "unprognostic (2.31e-2)" "unprognostic (3.07e-1)" "unprognostic (3.10e-2)" "unprognostic (2.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.16e-2)" "unprognostic (9.98e-2)" "unprognostic (2.90e-1)" "unprognostic (3.23e-1)" "unprognostic (1.83e-3)" "unprognostic (4.01e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (6.91e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-1)" "unprognostic (8.81e-2)" "unprognostic (8.31e-2)" 259.4 13.8 4.1 70.8 4.3 353.5 306.7 5.0 22.5 27919.2 28.9 97.8 4.5 107.1 16.5 1372.7 714.2 294.7 68.4 4.5 4.8 382.6 268.0 1181.7 2.0 5.6 5.5 11.5 36.1 5.5 470.2 8.3 5.5 112.6 106.7 0.6 14140.1 2946.3 599.9 272.4 19.9 14.0 4.8 22.5 154.7 28.1 10.4 47.7 30.4 51.5 215.8 226.6 685.3 4.8 4.9 19.4 0.0 0.3 0.2 0.0 1.1 0.1 0.0 0.1 0.0 1.5 318.7 0.9 1719.5 0.2 23.9 132.8 0.0 64.1 0.0 8.6 0.3 0.3 227.1 0.2 326.4 0.5 1.0 8.8 2037.1 0.1 134.0 0.0 0.2 0.0 0.2 0.3 0.0 0.4 0.4 24.4 0.4 767.9 120.1 0.6 0.7 0.1 355.5 14.6 0.3 0.0 622.1 131.4 1.8 0.4 2.8 531.8 0.3 0.4 8.5 1.2 1.1 1.2 9.7 6.1 0.0 33.0 0.5 3.6 0.9 0.4 0.1 3.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 321.8 0.0 4.0 0.0 0.0 7.9 4.1 4.3 5.0 22.5 4.5 4.8 5.6 5.5 5.5 4.8 10.4 4.8 6.3 1807.7 4134.5 0.3 5.4 100.7 1330.7 18759.4 2.2 0.0 594.2 607.6 3.9 1609.9 20435.8 3428.2 0.0 2.3 10.1 225.8 0.0 407.5 381.6 632.0 170.7 43.3 200.2 18.7 0.0 258.9 1.2 326.0 193.7 1398.8 77.0 0.0 15.7 508.5 6.8 0.0 0.0 74.7 2616.3 8.5 73.3 69.8 25.4 27.1 39.2 0.0 5.3 0.0 0.0 1.0 0.1 901.6 370.3 0.0 1.3 1289.4 2.7 3.4 8096.4 0.0 0.0 8.6 971.2 1.8 1.8 347.3 138.9 2.1 29.5 0.0 224.5 3338.5 SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1039.2;skin 1: 858.5" "Group enriched" "Detected in some" 16 "Squamous epithelial cells: 20.8;Suprabasal keratinocytes: 65.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;MCF7: 1.5;RT4: 1.1;T-47d: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" NA NA 7700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" 0.9 0.6 0.1 0.0 0.0 0.0 11.3 0.7 0.5 105.0 0.0 0.3 0.0 0.2 0.0 1039.2 0.2 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 70.1 0.0 1.4 858.5 0.3 0.0 0.0 0.2 0.8 0.3 0.1 0.9 0.2 0.0 17.4 0.3 206.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.6 0.0 0.0 1.8 1.5 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.8 65.8 0.0 0.0 0.0 0.0 0.8 SLURP2 ENSG00000283992 "Secreted LY6/PLAUR domain containing 2" P0DP57 8 142764338-142769828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 870.8;skin 1: 334.1;vagina: 219.7" "Cell type enhanced" "Detected in single" "Pancreatic endocrine cells: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HaCaT: 28.5" "Secreted in other tissues" NA NA 3100000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" 1.1 0.1 0.4 0.0 0.7 0.0 2.0 2.9 2.4 187.1 0.0 19.4 0.3 5.0 0.2 870.8 4.0 0.2 1.2 1.0 0.1 0.2 0.3 0.5 0.0 1.8 0.2 1.0 0.4 0.0 0.2 0.1 1.7 6.5 0.2 0.3 75.2 2.1 0.4 334.1 2.8 0.8 0.2 0.3 5.8 0.3 0.4 1.2 0.6 0.0 22.9 9.9 219.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.1 6.2 0.0 0.0 28.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 2.9 2.4 1.0 0.1 1.8 0.2 1.7 0.2 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMIM20 "C4orf52, MITRAC7, PNX" ENSG00000250317 "Small integral membrane protein 20" Q8N5G0 4 25861830-25929874 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016552 Approved Approved Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" Nucleoli "HPA016552: AB_1859536" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" "unprognostic (1.78e-1)" "unprognostic (6.52e-3)" "unprognostic (1.55e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.46e-1)" "unprognostic (1.02e-1)" "unprognostic (5.42e-2)" "unprognostic (2.86e-1)" "prognostic favorable (8.97e-5)" "unprognostic (5.51e-2)" "unprognostic (5.84e-2)" "unprognostic (1.53e-1)" "unprognostic (5.12e-3)" 27.9 36.7 36.7 16.6 37.7 13.1 27.2 38.1 50.2 22.2 39.8 30.9 39.9 23.9 72.2 15.7 23.8 23.9 46.8 36.5 38.4 46.0 38.2 19.7 30.4 36.9 36.1 33.9 43.4 28.2 17.6 14.1 36.9 23.9 25.5 29.9 35.1 17.5 95.9 13.9 35.1 17.8 37.9 23.6 38.6 20.5 36.8 17.4 31.4 61.4 24.8 28.8 19.1 39.2 29.9 24.5 32.3 31.3 34.9 75.4 43.0 28.4 34.3 24.0 30.4 21.9 51.6 48.8 48.1 31.7 49.6 8.5 37.9 36.3 33.4 27.9 30.1 28.3 16.4 42.0 59.1 34.0 18.0 53.9 71.6 30.6 46.1 46.7 18.7 32.5 45.9 15.5 29.6 19.1 37.0 57.5 61.0 39.6 36.1 30.1 42.0 31.7 53.5 21.6 41.3 38.4 18.3 12.7 66.0 35.2 26.3 47.5 31.4 25.8 30.5 29.3 36.8 30.2 26.9 52.6 39.2 35.6 33.4 30.6 31.5 15.9 26.2 37.7 34.5 47.3 37.5 33.2 36.9 47.9 50.4 41.1 16.3 35.6 29.4 38.3 42.9 31.7 36.7 37.7 38.1 50.2 36.5 38.4 36.9 36.1 36.9 37.9 36.8 39.2 21.5 9.6 41.6 9.4 48.0 21.9 30.4 89.4 26.7 7.7 49.8 63.1 61.8 61.5 59.0 36.8 8.4 63.7 22.5 50.9 131.0 70.0 11.5 34.7 30.6 23.1 19.3 9.2 3.8 62.5 59.7 40.0 31.6 34.6 10.8 37.1 21.8 66.5 69.7 1.7 4.6 64.0 59.0 62.9 32.1 23.1 37.6 44.5 44.4 4.7 42.9 95.3 38.1 9.5 7.9 46.2 44.6 48.2 38.4 38.9 130.1 166.5 47.0 22.2 72.3 26.8 35.8 44.5 36.4 27.3 19.5 43.8 29.8 71.2 65.4 30.8 SMIM31 LINC01207 ENSG00000248771 "Small integral membrane protein 31" A0A1B0GVY4 4 164754064-164803795 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 7.8;intestine: 24.6;prostate: 11.0" "Group enriched" "Detected in some" 5 "Exocrine glandular cells: 93.3;Pancreatic endocrine cells: 139.7" "Cancer enhanced" "Detected in many" "prostate cancer: 8.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted - unknown location" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (2.84e-1)" "unprognostic (1.18e-1)" "unprognostic (2.47e-2)" "unprognostic (1.87e-4)" "unprognostic (2.95e-2)" "unprognostic (1.78e-1)" "unprognostic (4.17e-2)" "unprognostic (4.82e-1)" "unprognostic (9.47e-2)" "unprognostic (5.63e-3)" 0.1 0.1 0.3 1.4 0.3 1.0 1.0 0.6 0.5 5.0 0.3 15.4 22.0 0.3 0.9 0.1 0.1 7.8 0.1 0.3 0.1 0.1 0.1 0.4 0.3 0.4 0.2 0.1 0.4 0.1 0.0 0.1 0.4 11.0 15.5 0.2 1.2 0.1 0.2 0.2 24.6 0.7 0.1 0.1 0.6 0.1 0.4 0.0 0.1 0.0 0.1 1.7 0.0 0.9 0.1 0.8 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.3 0.1 0.4 0.0 0.1 0.0 0.3 1.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.4 0.1 0.1 0.1 0.2 0.3 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.3 0.1 0.3 0.0 0.0 0.3 0.3 0.6 0.5 0.3 0.1 0.4 0.2 0.4 0.1 0.4 0.9 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 1.1 0.0 0.0 9.3 3.7 0.0 0.1 0.0 0.0 0.0 3.8 0.0 2.5 2.2 0.3 0.0 0.0 0.0 93.3 0.0 0.2 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.7 0.0 0.0 0.0 0.0 0.0 0.8 10.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;liver: 67.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.4;Oligodendrocyte precursor cells: 372.4;Oligodendrocytes: 81.1;Peritubular cells: 133.2" "Cancer enhanced" "Detected in many" "glioma: 27.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 50.3;HeLa: 122.6;HSkMC: 38.3;SiHa: 72.1;SK-BR-3: 30.6;U-266/70: 42.3;U-87 MG: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 140000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "CAB034427: AB_2193382, HPA004153: AB_1080035" "unprognostic (3.31e-1)" "unprognostic (2.17e-3)" "unprognostic (8.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.09e-3)" "unprognostic (4.76e-2)" "unprognostic (2.80e-2)" "unprognostic (5.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.09e-2)" "unprognostic (3.92e-1)" "unprognostic (2.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" 15.9 10.3 29.2 0.5 30.3 0.1 6.2 53.2 29.1 9.4 17.5 1.3 1.9 2.2 7.7 0.3 6.6 0.5 8.3 27.9 31.6 3.0 67.9 0.6 0.9 38.4 38.8 1.4 10.3 0.3 4.4 8.0 36.8 33.4 1.0 2.4 5.8 38.8 12.7 2.4 1.4 1.0 41.2 27.2 3.8 35.7 29.6 0.4 4.2 2.7 0.5 1.3 6.3 52.8 0.0 3.3 50.3 0.0 9.8 6.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 2.9 0.0 0.0 20.4 0.0 122.6 17.4 0.1 0.0 0.0 38.3 11.9 1.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.0 0.2 72.1 30.6 0.0 0.3 0.0 0.0 0.4 0.3 2.9 0.0 0.0 42.3 0.0 0.0 51.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.2 30.3 53.2 29.1 27.9 31.6 38.4 38.8 36.8 41.2 29.6 52.8 0.3 0.0 0.0 12.1 2.5 0.3 0.0 0.7 0.0 2.1 1.3 3.8 2.0 7.2 0.1 0.0 16.7 24.2 4.0 0.0 0.0 0.3 4.7 11.9 0.6 2.9 15.6 0.0 1.0 2.3 0.8 6.0 3.6 1.5 0.0 1.4 3.3 104.4 2.8 0.0 13.5 0.1 14.2 2.5 0.4 19.0 7.8 0.3 0.0 1.0 0.1 0.3 0.0 372.4 81.1 3.7 0.1 133.2 12.4 0.0 0.0 0.0 1.1 0.3 0.0 0.7 2.3 2.1 3.9 0.0 0.4 40.2 0.4 0.4 0.0 0.1 SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 149.8;Leydig cells: 321.8;Peritubular cells: 769.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.1;EFO-21: 2.8;RPMI-8226: 11.3;RPTEC TERT1: 3.8;SuSa: 9.1" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in single" "spinal cord: 1.4" "Secreted to extracellular matrix" NA NA 120000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.23e-1)" "unprognostic (5.29e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (6.20e-3)" 67.8 14.0 10.6 13.0 12.7 0.0 61.0 10.8 16.2 82.1 42.3 44.1 21.4 164.0 147.2 53.1 119.6 100.8 57.2 10.6 11.3 13.0 4.0 14.7 14.7 11.8 11.8 124.1 25.2 12.2 4.5 18.8 11.9 31.0 24.9 2.8 17.1 54.6 42.1 28.9 27.8 76.5 10.2 4.4 144.7 44.2 12.2 10.9 43.5 54.8 11.1 68.7 21.8 10.0 2.4 0.0 8.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.4 1.0 0.0 0.0 0.0 0.0 11.3 3.8 0.0 1.7 0.3 0.0 0.3 0.1 9.1 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 12.7 10.8 16.2 10.6 11.3 11.8 11.8 11.9 10.2 12.2 10.0 8.1 0.0 1.7 0.7 0.0 11.1 8.0 0.0 1.2 7.1 12.5 12.1 7.7 0.0 1.8 11.0 0.0 2.5 0.0 3.6 0.0 0.0 2.6 40.3 42.3 11.0 19.7 0.0 0.5 0.0 1.7 149.8 1.1 58.4 0.0 17.2 3.3 0.0 1.2 0.0 9.7 4.5 0.0 0.0 3.9 17.2 321.8 2.9 3.6 6.5 0.0 0.4 0.0 2.0 0.1 0.1 0.4 769.2 0.1 6.7 2.0 0.0 2.2 0.8 46.0 14.7 63.3 3.9 5.1 0.8 2.7 2.6 1.7 17.3 47.4 1.1 SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 131.3;Late spermatids: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 139.1;fHDF/TERT166: 144.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" 21.8 36.5 38.8 13.9 44.7 7.3 20.1 45.1 43.0 21.2 33.9 25.3 16.8 20.9 14.4 20.6 14.6 21.5 55.8 39.1 43.0 73.7 95.3 31.3 14.6 42.7 42.6 17.9 32.8 34.2 41.9 21.6 43.3 29.4 14.9 8.5 29.0 20.0 37.9 37.9 23.8 17.6 40.9 21.1 25.4 14.0 47.5 17.8 34.0 29.4 11.0 23.6 21.0 46.8 16.4 13.1 10.1 26.5 139.1 72.2 17.1 60.4 95.0 27.7 33.0 22.0 11.9 4.7 27.4 144.0 59.3 7.4 8.4 12.7 13.0 21.0 9.6 5.1 19.5 6.0 62.3 3.7 37.4 96.0 23.4 25.9 17.7 100.9 61.6 1.7 9.1 30.5 58.9 17.0 0.1 6.5 3.9 23.2 22.3 1.2 5.5 7.0 23.9 6.2 17.0 9.7 27.6 19.5 38.5 12.9 7.3 7.0 53.9 103.0 10.9 59.1 15.4 37.6 44.0 3.5 93.7 10.8 47.1 1.9 2.5 3.4 6.4 2.1 5.0 1.5 5.5 5.0 1.3 3.1 10.0 10.1 2.5 6.6 0.6 1.7 4.7 3.2 38.8 44.7 45.1 43.0 39.1 43.0 42.7 42.6 43.3 40.9 47.5 46.8 14.1 25.6 14.4 10.7 12.2 7.9 22.8 15.3 6.8 12.6 13.7 9.0 37.7 24.3 12.8 25.8 25.0 38.8 11.5 131.3 11.7 53.4 50.0 6.2 13.0 18.6 23.8 9.9 5.8 38.2 14.4 31.4 15.8 21.0 10.8 9.4 26.7 88.5 34.1 20.2 5.5 20.3 24.4 15.5 6.2 200.7 11.5 15.8 55.2 4.7 7.8 16.4 36.0 6.6 15.5 24.7 83.1 13.5 23.1 26.0 51.7 75.1 2.4 5.2 0.0 8.9 17.1 1.4 3.1 7.5 8.0 34.3 23.3 10.2 18.0 15.4 SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.3;Distal enterocytes: 291.5;Paneth cells: 157.5;Proximal enterocytes: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 44.2;hTCEpi: 36.9;OE19: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 15.0 23.3 4.6 18.7 5.1 22.9 23.7 8.2 9.4 72.8 8.9 60.7 45.5 13.3 6.5 13.6 7.9 17.2 5.6 5.3 5.7 47.4 80.0 14.1 21.4 5.9 5.4 9.1 20.8 32.4 7.5 44.0 5.9 21.8 65.7 6.0 13.7 16.6 39.8 64.5 77.3 8.5 5.7 27.0 30.5 2.9 5.4 5.1 9.1 55.8 16.2 35.5 30.9 7.7 0.3 2.6 6.1 2.8 44.2 19.9 19.5 10.4 27.8 3.1 6.6 3.3 2.7 0.0 1.4 6.6 8.2 4.9 1.7 5.3 2.6 0.0 5.4 2.5 9.8 9.0 28.3 0.0 0.1 24.4 36.9 3.0 5.3 12.0 5.5 0.0 3.8 0.0 12.7 9.3 0.0 0.2 1.1 58.8 8.0 0.0 10.8 0.4 15.1 4.2 4.4 0.1 1.5 18.5 27.9 3.9 3.1 1.4 11.0 5.9 3.5 0.6 6.8 0.0 0.0 0.0 8.7 4.9 13.7 80.9 4.0 1.1 0.0 4.3 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 7.5 0.0 0.0 1.4 4.6 5.1 8.2 9.4 5.3 5.7 5.9 5.4 5.9 5.7 5.4 7.7 11.8 3.2 17.8 5.2 2.4 53.7 24.5 13.7 15.9 3.0 12.2 6.6 4.0 25.8 9.7 5.5 4.2 156.3 0.4 291.5 56.7 24.6 0.2 4.2 12.6 7.1 48.7 5.7 7.4 25.7 40.4 46.3 34.7 5.2 10.1 0.8 18.9 77.8 62.7 3.3 10.5 61.7 59.0 126.3 10.0 1.2 15.5 33.4 35.6 11.2 9.9 11.5 2.1 11.1 11.0 19.5 157.5 14.3 0.9 16.7 383.1 129.3 7.5 6.2 13.1 12.8 9.9 1.1 3.7 15.5 76.0 115.1 2.0 11.4 38.9 16.6 SMPDL3B ASML3B ENSG00000130768 "Sphingomyelin phosphodiesterase acid like 3B" Q92485 1 27935000-27959157 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.1;pancreas: 49.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.1;Ductal cells: 31.5;Paneth cells: 47.5;Proximal enterocytes: 37.4;Undifferentiated cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "eosinophil: 3.3;myeloid DC: 1.3;neutrophil: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.3;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "BEWO: 46.0;CAPAN-2: 35.3;NTERA-2: 27.6;RPMI-8226: 30.1;SK-BR-3: 45.9;T-47d: 33.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA030561 Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 400000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Golgi apparatus" "HPA030561: AB_10604095" "unprognostic (1.22e-2)" "unprognostic (4.45e-1)" "unprognostic (4.58e-3)" "unprognostic (3.83e-2)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.50e-1)" "unprognostic (2.68e-1)" "unprognostic (3.95e-1)" "unprognostic (6.02e-2)" "unprognostic (1.64e-1)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.48e-1)" "unprognostic (4.40e-2)" "unprognostic (3.09e-3)" 1.5 0.3 0.5 2.2 0.6 2.0 5.7 2.5 0.6 2.8 2.0 22.2 24.1 1.9 15.8 1.1 7.0 2.2 0.3 1.1 0.7 5.2 0.4 6.6 1.2 0.4 0.4 0.2 49.4 7.9 1.0 0.3 0.5 3.6 23.6 0.1 12.5 0.5 0.0 0.9 14.2 1.0 0.6 1.7 16.5 0.7 0.8 0.5 13.9 0.0 3.1 2.2 0.4 0.6 5.4 2.5 0.0 0.3 0.0 0.0 46.0 0.0 1.1 0.6 3.4 12.1 35.3 1.7 8.3 0.0 0.7 5.9 3.8 3.2 0.5 0.0 23.6 7.9 0.5 3.0 0.0 2.6 0.0 0.2 2.9 7.0 0.4 1.0 1.0 0.3 1.0 0.4 0.0 19.5 0.1 0.8 27.6 4.1 4.3 0.5 0.2 30.1 24.6 9.5 23.4 0.5 0.0 45.9 1.3 4.7 33.3 1.4 0.0 0.0 7.6 0.1 0.0 0.3 12.9 0.6 0.8 0.0 0.1 0.1 0.1 3.3 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.2 0.1 0.0 1.8 0.3 0.0 0.0 0.0 0.1 0.5 0.6 2.5 0.6 1.1 0.7 0.4 0.4 0.5 0.6 0.8 0.6 0.1 9.6 17.9 0.0 2.3 0.1 2.7 4.0 0.0 0.0 15.0 6.5 0.4 1.5 13.8 9.2 0.0 2.5 0.5 38.1 0.0 31.5 0.4 2.2 0.3 1.1 20.4 1.3 0.8 23.3 0.2 0.2 18.3 5.6 0.0 2.0 0.4 0.0 0.3 0.0 0.1 21.6 10.2 0.0 0.4 0.2 0.0 0.9 0.0 1.0 0.0 0.0 0.0 1.0 0.0 21.7 47.5 0.0 16.6 3.7 37.4 8.7 2.7 0.0 0.0 0.0 0.8 0.0 0.2 0.6 0.1 7.7 0.8 0.1 31.2 3.0 SMR3A "PBI, PRL5, PROL5" ENSG00000109208 "Submaxillary gland androgen regulated protein 3A" Q99954 4 70360760-70367158 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "salivary gland: 59.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 0.7;liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044567 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Mammary glandular cells - Lactation" "HPA044567: AB_10796114" "unprognostic (2.06e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMR3B "P-B, PRL3, PROL3" ENSG00000171201 "Submaxillary gland androgen regulated protein 3B" P02814 4 70370093-70390244 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 946 "salivary gland: 217144.9" "Group enriched" "Detected in some" 55 "Breast glandular cells: 2.3;Early spermatids: 8.4;Late spermatids: 6.0" "Cancer enriched" "Detected in some" 22 "breast cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 39 "EFO-21: 4.5" "Secreted to digestive system" NA NA 1900000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 38: EFO-21 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (3.72e-1)" 0.0 9.1 0.0 0.0 0.0 7.6 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.1 8.9 0.0 0.0 44.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 47.3 229.5 0.0 1.6 23.2 0.0 1.6 0.0 0.0 217144.9 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SNED1 "FLJ00133, Snep, SST3" ENSG00000162804 "Sushi, nidogen and EGF like domains 1" Q8TER0 2 240998618-241095568 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 95.0;Excitatory neurons: 86.0;Leydig cells: 95.1;Microglial cells: 77.8;Peritubular cells: 71.1;Skeletal myocytes: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "ASC TERT1: 410.4;HSkMC: 211.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036414, HPA036415" Uncertain "Secreted to blood" NA NA 27000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA036414: AB_10960852, HPA036415: AB_10964128" "unprognostic (1.41e-1)" "unprognostic (3.92e-2)" "unprognostic (1.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.57e-3)" "unprognostic (4.62e-2)" "unprognostic (7.77e-4)" "unprognostic (3.49e-2)" "unprognostic (4.96e-1)" "unprognostic (7.85e-3)" "unprognostic (3.42e-2)" "unprognostic (2.06e-2)" "unprognostic (2.80e-2)" "unprognostic (1.16e-1)" "unprognostic (3.72e-1)" "unprognostic (5.51e-3)" "unprognostic (4.95e-3)" 23.8 9.3 4.2 6.4 8.5 1.2 15.8 14.1 6.9 34.1 32.4 7.3 4.5 18.0 11.8 6.1 21.6 18.7 11.1 10.7 11.7 7.1 8.0 13.3 4.7 8.3 6.4 21.9 7.3 3.1 7.2 1.9 4.8 12.5 3.4 2.5 14.6 7.5 19.8 12.1 10.4 6.3 0.6 14.1 5.7 9.3 2.2 3.3 30.2 9.1 2.9 11.5 10.7 5.9 0.1 0.6 0.4 4.8 61.1 410.4 0.3 2.4 1.5 0.5 0.2 0.2 0.2 0.1 1.0 4.4 0.5 0.2 0.4 0.0 0.3 2.7 1.0 0.2 4.5 0.4 2.6 0.2 0.5 211.6 0.1 0.5 0.3 28.4 9.5 0.2 0.1 2.7 11.5 2.4 1.6 0.2 0.7 0.1 0.3 0.2 8.1 0.1 5.6 0.5 0.8 0.3 1.9 8.3 4.2 0.6 1.8 0.8 23.7 8.7 0.6 50.9 1.5 0.8 0.4 1.5 11.7 0.1 2.6 0.0 0.0 0.0 0.0 0.3 0.3 1.9 0.4 0.2 0.0 0.6 0.2 0.2 0.0 0.0 0.7 0.0 0.4 0.0 4.2 8.5 14.1 6.9 10.7 11.7 8.3 6.4 4.8 0.6 2.2 5.9 8.0 6.4 11.0 95.0 8.4 3.6 0.9 0.4 2.8 2.8 1.1 1.8 2.4 1.5 8.5 5.5 0.0 0.1 0.3 0.3 0.0 1.2 1.3 10.6 16.8 10.9 2.4 3.2 86.0 1.2 0.1 22.1 2.6 10.7 0.0 5.0 22.9 5.8 0.2 1.7 32.5 0.2 0.0 2.9 5.9 5.9 95.1 2.7 1.8 77.8 0.6 7.4 0.0 11.6 7.0 0.7 0.1 71.1 0.9 3.0 0.0 0.5 4.2 1.2 26.3 53.7 4.9 0.6 1.5 0.7 2.6 0.4 1.8 36.4 0.5 0.6 SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 436.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 498.5;Leydig cells: 424.1;Peritubular cells: 365.6;Smooth muscle cells: 428.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.2;BJ: 38.1;PC-3: 55.1;RPTEC TERT1: 231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" NA NA 50400000 510000000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA042110: AB_2677850" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" 221.4 20.4 14.3 26.1 20.9 0.0 134.2 15.8 23.8 226.5 436.1 122.7 18.2 151.6 10.4 62.1 177.6 22.4 150.1 47.1 14.1 124.1 16.5 155.0 10.6 22.9 23.4 59.7 86.7 2.6 19.8 39.8 17.5 131.3 13.4 1.9 70.9 23.4 22.0 91.9 65.2 37.1 16.4 24.8 102.1 74.1 19.0 5.8 176.6 22.9 7.0 178.3 170.4 13.6 0.0 0.0 0.0 0.0 66.2 17.3 2.0 38.1 16.7 2.3 1.4 0.5 0.0 0.0 11.8 8.0 0.1 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.0 16.8 0.0 15.8 0.0 17.9 0.1 0.0 1.1 0.0 0.0 0.1 0.3 1.1 8.0 0.0 55.1 0.0 0.0 0.6 231.3 0.8 0.2 0.2 0.0 1.2 0.0 2.1 32.8 0.0 0.0 8.7 1.0 1.6 0.4 0.1 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 20.9 15.8 23.8 47.1 14.1 22.9 23.4 17.5 16.4 19.0 13.6 46.1 12.8 18.1 7.2 1.0 90.8 65.5 0.6 10.2 0.4 21.7 22.1 23.0 144.4 7.6 90.1 0.0 211.4 1.8 25.6 15.6 63.6 18.7 81.9 45.8 21.0 34.6 0.0 0.1 1.8 17.0 498.5 5.1 80.3 0.0 0.1 15.4 0.2 17.3 0.0 0.1 51.9 0.0 0.3 115.5 33.9 424.1 3.2 80.0 3.7 0.0 20.7 0.0 0.5 0.7 3.5 89.3 365.6 1.1 80.4 0.0 142.7 0.1 1.4 197.2 6.5 428.9 73.2 4.4 6.1 70.3 190.0 7.6 6.1 51.8 9.6 SOGA1 "C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA" ENSG00000149639 "Suppressor of glucose, autophagy associated 1" O94964 20 36777447-36863538 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 63.9" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 54.8;Oligodendrocytes: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043992 Approved Approved Nucleoli,Cytosol "Secreted to blood" NA Yes "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" "HPA043992: AB_2678762" "unprognostic (2.34e-2)" "unprognostic (1.35e-1)" "unprognostic (6.58e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (2.27e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (1.09e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.49e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (4.45e-3)" 6.6 14.2 13.4 3.6 18.1 1.1 6.2 63.9 16.4 9.5 0.0 12.3 1.9 10.9 3.8 7.0 9.6 4.8 9.5 12.8 14.4 7.8 0.9 6.2 2.5 14.6 15.0 10.4 2.8 7.3 4.9 6.2 12.6 9.0 2.8 4.5 4.7 8.8 2.4 8.6 5.8 8.4 8.8 4.6 6.4 7.9 15.1 2.9 12.2 3.9 3.1 11.2 7.4 21.9 13.4 18.0 21.5 23.2 12.2 11.2 5.6 11.6 12.5 16.1 9.5 7.3 2.1 6.0 4.2 20.4 14.0 17.8 17.3 10.8 16.8 0.9 3.4 9.7 18.5 9.7 6.4 2.1 9.0 6.3 13.0 15.4 10.9 7.0 10.6 6.5 6.9 1.2 17.8 13.0 6.9 5.1 5.5 1.3 13.8 16.1 19.9 2.3 9.5 4.0 25.5 15.9 24.1 26.1 7.5 9.4 33.3 14.4 16.3 40.2 7.7 19.9 25.7 2.4 0.6 5.8 17.1 2.8 26.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 13.4 18.1 63.9 16.4 12.8 14.4 14.6 15.0 12.6 8.8 15.1 21.9 16.5 0.0 1.8 18.9 4.4 12.6 5.4 6.3 13.6 26.3 9.6 8.9 16.1 5.7 6.7 20.2 37.5 15.6 11.3 1.7 1.9 3.8 0.9 8.6 20.5 14.5 6.0 1.3 19.9 1.5 10.2 12.0 0.5 21.9 10.8 33.0 10.4 0.6 10.0 23.5 30.3 1.5 0.0 7.6 10.7 2.4 12.2 8.1 5.4 21.5 4.5 17.8 0.0 54.8 50.9 1.4 2.4 18.8 1.8 6.0 2.1 1.5 3.9 3.8 13.1 23.2 16.9 0.5 1.3 13.7 16.1 3.3 1.4 14.0 3.0 2.9 SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 79.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 387.8;Excitatory neurons: 247.4;Microglial cells: 404.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 125.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 125.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 142.8;Daudi: 68.7;OE19: 93.5;RT4: 102.1;U-698: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" NA NA 79000 "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB011500: AB_443414, HPA031321: AB_2673826" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (9.53e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-3)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.80e-7)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-2)" 7.0 6.1 29.1 24.4 39.1 47.4 13.9 49.5 35.5 44.4 0.0 17.3 11.6 5.4 8.9 5.4 40.1 7.3 2.4 33.8 39.7 19.0 58.2 10.4 21.1 40.3 46.8 9.0 8.0 10.4 16.8 2.3 47.0 20.8 16.9 20.3 21.8 25.4 1.7 3.4 18.1 4.5 45.3 21.8 10.3 5.1 38.8 17.0 13.5 4.0 23.0 15.7 6.6 79.1 1.3 8.1 7.3 1.1 0.0 0.0 7.4 0.4 2.4 0.3 0.0 11.9 142.8 68.7 8.5 1.8 10.5 47.4 9.1 7.0 0.1 0.0 2.6 0.0 10.3 16.8 0.1 29.6 0.1 0.0 7.6 0.0 25.8 4.0 0.0 8.7 0.0 0.7 0.0 9.7 7.1 15.3 8.8 93.5 10.8 7.7 0.4 1.6 15.8 102.1 5.1 1.5 15.2 21.5 0.0 16.0 21.0 9.5 0.3 0.1 4.9 1.0 0.0 0.0 0.0 139.8 0.1 38.6 0.4 44.3 15.9 59.1 22.1 6.9 29.3 1.9 24.6 20.0 6.6 5.1 23.1 20.8 125.7 20.9 9.4 16.4 19.3 21.2 29.1 39.1 49.5 35.5 33.8 39.7 40.3 46.8 47.0 45.3 38.8 79.1 1.6 6.4 23.3 160.9 20.7 4.5 42.3 23.3 18.2 68.8 44.5 22.0 12.3 18.6 36.8 79.1 387.8 0.4 130.1 132.1 0.0 10.3 1.2 21.6 2.9 10.3 6.1 8.8 247.4 0.7 0.7 5.8 14.3 24.7 12.0 20.6 34.6 114.5 39.1 50.5 80.1 54.6 40.7 62.4 16.9 5.0 77.9 67.0 3.6 404.7 97.5 28.0 146.2 74.9 86.0 6.4 81.1 57.9 28.6 36.1 168.6 1.0 15.6 31.2 0.0 19.5 10.3 2.9 18.8 20.8 2.4 0.4 60.2 32.7 42.2 33.4 SOST "DAND6, VBCH" ENSG00000167941 Sclerostin Q9BQB4 17 43753738-43758791 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" Heparin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "kidney: 13.3" "Cell type enhanced" "Detected in some" "B-cells: 1.4;Collecting duct cells: 1.8" "Cancer enhanced" "Detected in some" "lung cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 5.2;SuSa: 3.0" "Group enriched" "Detected in some" 11 "basal ganglia: 1.7;cerebellum: 1.0" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA 16000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.26e-1)" "unprognostic (4.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.55e-3)" "unprognostic (3.37e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-1)" "unprognostic (8.35e-2)" "unprognostic (1.38e-2)" "unprognostic (1.20e-1)" "unprognostic (8.92e-2)" "unprognostic (1.56e-1)" "unprognostic (7.90e-2)" 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 13.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SPACA3 "ALLP17, CT54, LYC3, LYZL3, SLLP1" ENSG00000141316 "Sperm acrosome associated 3" Q8IXA5 17 32970376-32997877 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 125.3" "Group enriched" "Detected in some" 75 "Early spermatids: 1298.4;Late spermatids: 933.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 5 "B-cells: 1.2" "Cell line enriched" "Detected in some" 16 "U-266/70: 91.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA023633 Enhanced "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA023633: AB_1857407" "unprognostic (6.48e-2)" "unprognostic (2.83e-1)" "unprognostic (1.30e-1)" "unprognostic (7.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.31e-2)" "unprognostic (3.37e-1)" "unprognostic (5.91e-2)" "unprognostic (1.68e-1)" "unprognostic (5.70e-4)" "unprognostic (3.86e-2)" "unprognostic (1.79e-1)" "unprognostic (4.63e-1)" 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.7 0.3 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 20.9 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.2 125.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 91.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.7 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1298.4 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 1.6 0.0 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 933.6 13.1 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 4.9 0.4 0.0 3.8 0.0 0.7 0.0 6.6 0.0 0.0 14.7 6.9 0.0 0.0 0.0 0.0 0.1 0.9 0.0 SPACA5 "dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288" ENSG00000171489 "Sperm acrosome associated 5" Q96QH8 X 48004336-48009729 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 14.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Early spermatids: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA044747: AB_2679071, HPA047149: AB_2679955" 0.0 0.0 0.6 0.0 0.7 0.1 0.1 1.2 0.9 0.1 0.2 0.1 0.0 0.2 0.5 0.0 0.2 0.1 0.0 0.3 0.6 0.1 0.0 0.1 0.4 0.7 0.7 0.2 0.9 0.0 0.0 0.0 0.7 0.2 0.1 0.3 0.1 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 14.0 0.8 0.0 0.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.6 0.7 1.2 0.9 0.3 0.6 0.7 0.7 0.7 0.2 0.8 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPACA5B LYZL5B ENSG00000171478 "Sperm acrosome associated 5B" Q96QH8 X 48130657-48132613 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 23.9" "Cell type enriched" "Detected in single" 16 "Early spermatids: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA044747: AB_2679071, HPA047149: AB_2679955" 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.4 0.2 0.4 0.2 0.3 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPACA7 C13orf28 ENSG00000153498 "Sperm acrosome associated 7" Q96KW9 13 112376355-112434689 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 109 "testis: 84.1" "Group enriched" "Detected in some" 22 "Early spermatids: 1259.3;Late spermatids: 829.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA048349 Enhanced "Secreted in male reproductive system" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA048349: AB_2732548" "unprognostic (3.97e-2)" 0.0 0.1 0.1 0.1 0.4 0.5 0.0 0.7 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 84.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.7 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.7 0.4 0.2 0.2 0.3 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1259.3 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 829.7 6.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.7 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAG11A "EDDM2A, HE2" ENSG00000178287 "Sperm associated antigen 11A" Q6PDA7 8 7847876-7868867 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11461 "epididymis: 4564.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;NB-4: 5.7;RPMI-8226: 1.7" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA023842: AB_2732429, HPA057479: " 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4564.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAG11B "EDDM2B, EP2, EP2C, EP2D, HE2" ENSG00000164871 "Sperm associated antigen 11B" Q08648 8 7442684-7463674 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1636 "epididymis: 864.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA023842: AB_2732429, HPA057479: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 864.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4430.9;Endothelial cells: 2372.1;Peritubular cells: 2523.5;Sertoli cells: 4674.1;Skeletal myocytes: 2379.0;Smooth muscle cells: 2781.9" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 24.9;SuSa: 31.4;U-266/70: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Enhanced "Secreted in other tissues" NA NA 630000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" 755.6 129.5 664.6 124.5 810.9 0.5 532.1 612.4 1058.4 732.7 580.4 624.3 125.1 1244.5 443.8 308.1 754.5 487.9 600.2 744.6 723.5 72.5 25.0 481.1 99.1 655.7 730.9 286.8 91.8 128.0 197.8 315.4 663.4 584.2 187.5 95.2 228.3 999.2 244.8 130.2 280.1 1191.2 774.7 157.9 347.7 97.5 694.8 103.2 369.9 594.7 100.0 488.0 466.4 681.2 0.7 0.0 24.9 0.3 0.2 0.1 2.6 0.1 0.1 0.0 0.0 0.0 0.1 0.4 1.8 0.0 0.0 1.4 2.4 0.0 0.0 1.7 0.0 0.3 1.1 0.4 1.1 0.3 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.5 0.2 3.5 0.6 0.0 0.0 0.3 0.4 1.2 0.0 0.1 0.8 1.6 0.1 0.2 0.1 31.4 0.4 0.5 0.0 0.2 0.3 1.5 0.2 9.1 1.4 0.6 3.4 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 664.6 810.9 612.4 1058.4 744.6 723.5 655.7 730.9 663.4 774.7 694.8 681.2 4430.9 12.8 56.4 1155.7 6.2 46.3 187.2 0.6 59.7 10.7 24.4 251.6 334.2 4.3 43.3 7.3 2.1 2.2 8.6 0.0 13.7 0.8 11.8 34.9 935.8 2372.1 0.0 32.0 382.3 0.4 3.2 1413.1 6.1 46.7 7.6 1.4 899.5 9.1 9.2 3.3 450.1 0.0 0.0 5.3 55.2 47.0 659.5 31.6 56.9 261.4 0.0 179.4 0.0 210.6 53.8 0.1 0.0 2523.5 25.2 50.4 0.0 24.6 7.4 34.4 4674.1 2379.0 2781.9 5.7 7.9 56.8 39.9 2.5 26.9 38.8 0.0 124.2 SPATA20 "FLJ21347, SSP411, Tisp78" ENSG00000006282 "Spermatogenesis associated 20" Q8TB22 17 50543058-50555852 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 117.5" "Group enriched" "Detected in all" 15 "Early spermatids: 594.1;Late spermatids: 1543.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 60.1;MCF7: 59.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022023, HPA027144, HPA031442" Enhanced Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA022023: AB_1857417, HPA027144: AB_1857418, HPA031442: AB_10610557" "unprognostic (9.27e-3)" "unprognostic (1.90e-1)" "unprognostic (9.60e-2)" "unprognostic (9.74e-3)" "unprognostic (2.63e-3)" "unprognostic (7.23e-2)" "unprognostic (1.56e-1)" "unprognostic (3.07e-1)" "unprognostic (7.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.12e-3)" "unprognostic (4.93e-2)" "unprognostic (6.74e-2)" "unprognostic (1.75e-1)" "unprognostic (2.29e-1)" "unprognostic (2.66e-1)" "prognostic favorable (9.69e-5)" 10.3 36.8 25.7 7.2 24.6 4.4 10.5 25.5 33.2 16.9 30.0 14.8 10.0 18.0 9.7 10.1 13.7 12.9 33.3 24.2 27.6 18.6 17.6 8.9 6.4 26.9 28.0 21.1 22.0 17.0 11.7 6.4 27.5 17.1 6.4 3.2 17.7 11.2 18.5 8.6 10.8 8.3 26.0 14.1 22.0 117.5 33.1 2.3 22.5 18.4 3.8 14.6 10.3 24.8 8.8 39.4 4.8 25.7 7.9 22.7 6.0 14.9 24.2 9.2 7.3 29.1 12.9 9.2 38.4 13.9 8.9 7.0 1.4 6.3 4.2 14.4 5.3 7.4 9.5 60.1 27.8 2.4 17.1 33.3 8.8 4.7 13.0 17.9 11.6 2.4 0.7 16.8 5.5 59.3 0.0 2.1 3.1 19.0 18.0 4.4 6.9 2.9 35.4 39.5 4.5 11.3 13.0 12.1 17.0 5.6 21.0 1.1 19.7 9.8 22.2 5.6 3.7 31.8 14.0 0.2 14.9 1.4 6.9 0.0 5.0 1.0 1.6 4.5 1.9 2.8 1.2 1.1 8.3 1.7 1.5 1.7 0.2 7.3 3.4 1.6 0.8 3.7 25.7 24.6 25.5 33.2 24.2 27.6 26.9 28.0 27.5 26.0 33.1 24.8 12.6 6.4 5.0 17.3 14.0 10.7 15.1 13.4 25.6 5.3 13.3 17.4 32.5 20.0 13.1 23.9 4.2 17.3 9.8 32.6 27.4 35.6 594.1 13.0 13.2 11.7 37.9 6.1 10.3 39.0 10.3 23.5 66.8 23.2 17.7 38.5 10.8 26.7 34.6 11.8 9.5 28.4 16.2 23.6 14.8 1543.1 38.2 20.0 21.4 6.5 19.3 26.9 12.3 8.5 2.3 23.7 31.1 38.0 17.9 12.2 18.4 38.8 5.9 2.4 6.6 18.1 19.1 10.0 13.8 11.9 8.8 9.9 11.2 39.9 23.8 17.1 SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.2" "Group enriched" "Detected in many" 4 "Early spermatids: 400.4;Spermatocytes: 455.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 17.8;BJ hTERT+ SV40 Large T+ RasG12V: 18.6;HBF TERT88: 21.7;HMC-1: 13.4;OE19: 15.9;RPTEC TERT1: 26.8;SCLC-21H: 19.9;WM-115: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045936, HPA051040" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" NA NA 52000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA045936: AB_2679504, HPA051040: AB_2681322" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (9.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (5.96e-2)" "unprognostic (2.79e-1)" "unprognostic (2.40e-1)" "unprognostic (8.99e-2)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (9.67e-2)" 2.3 3.4 1.1 0.8 1.1 0.4 2.2 1.2 1.6 1.2 1.0 1.6 1.2 1.5 6.3 2.6 1.8 3.5 3.1 1.1 1.2 2.0 1.2 1.1 0.8 1.3 1.2 3.4 1.9 4.7 1.2 12.9 1.3 3.5 1.1 2.8 1.8 2.9 1.6 1.0 0.9 1.2 1.3 1.3 1.5 73.2 1.1 0.9 1.9 1.9 0.7 2.4 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 17.8 18.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 21.7 5.0 0.0 0.0 0.0 0.0 6.3 0.0 13.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 2.9 0.0 0.0 3.3 15.9 0.0 0.0 1.4 0.0 26.8 0.2 19.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 31.6 1.1 1.3 0.4 0.2 1.1 0.5 0.5 0.4 0.3 0.8 0.3 0.3 0.5 0.5 0.2 0.8 0.4 0.4 0.5 1.1 1.1 1.2 1.6 1.1 1.2 1.3 1.2 1.3 1.3 1.1 1.6 5.1 0.0 0.0 0.0 0.2 1.9 3.0 23.7 1.8 1.0 2.7 4.1 4.1 1.5 4.0 7.3 4.2 92.3 0.3 0.2 1.9 2.1 400.4 3.9 3.4 3.6 1.8 0.8 0.0 2.7 7.2 5.5 0.0 2.0 0.0 1.7 2.2 1.8 7.8 0.0 0.0 0.9 6.1 2.1 3.3 90.3 21.1 1.2 5.4 0.0 1.0 5.3 0.0 0.0 0.0 0.9 0.0 8.6 0.0 3.3 0.0 3.9 6.3 5.6 46.0 3.4 4.2 455.0 88.7 1.1 2.3 62.1 0.5 11.1 0.2 1.5 SPINK1 "PCTT, PSTI, Spink3, TATI" ENSG00000164266 "Serine peptidase inhibitor Kazal type 1" P00995 5 147824572-147831671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "pancreas: 53063.4" "Group enriched" "Detected in many" 9 "Exocrine glandular cells: 50621.7;Pancreatic endocrine cells: 16750.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 513.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "CACO-2: 417.2;RT4: 1139.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026366, HPA027498" Enhanced "Secreted to digestive system" NA NA 8000000 "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB026366: , HPA027498: AB_10603115" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (9.96e-3)" "unprognostic (3.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.79e-4)" "unprognostic (8.34e-3)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "unprognostic (1.88e-1)" "unprognostic (3.82e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.44e-7)" "unprognostic (7.98e-2)" "unprognostic (2.07e-1)" "prognostic favorable (2.15e-5)" 8.8 1.5 0.1 36.4 0.1 6.8 4.1 0.3 1.2 3.1 0.3 428.2 394.4 5.5 0.8 2.9 1.3 111.9 12.0 0.2 0.2 142.5 491.8 2.7 2.7 0.1 0.1 25.6 53063.4 0.0 1.9 3.2 0.2 4.4 441.3 0.6 12.8 1.4 1.2 21.1 403.9 14.1 0.0 2.5 1475.2 0.9 0.3 0.4 1.0 0.0 0.3 995.6 10.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 417.2 0.3 0.1 6.8 0.0 0.8 0.9 2.2 0.0 0.0 3.9 0.0 0.0 0.0 107.0 0.3 0.0 3.9 0.0 2.1 0.0 3.0 5.8 0.0 0.0 0.0 0.3 0.0 0.3 0.8 1.3 2.1 138.9 0.8 0.8 0.0 2.5 0.0 1139.0 0.5 1.7 0.0 0.2 0.1 5.4 0.1 0.0 0.0 0.1 13.7 1.1 3.8 2.2 5.9 3.0 16.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 1.2 0.2 0.2 0.1 0.1 0.2 0.0 0.3 0.6 0.0 0.0 3.6 0.0 9.7 0.0 15.1 0.3 0.0 0.0 5.5 0.8 0.1 1451.2 11.1 377.0 0.0 0.0 0.0 280.8 86.1 1286.7 0.1 0.3 0.4 9.4 517.2 18.7 1.0 50621.7 0.1 1.9 1580.5 5.0 4.5 2.0 39.3 3385.8 0.1 0.0 0.2 2087.4 0.0 30.9 0.0 0.2 0.0 13.7 0.0 0.0 269.8 0.0 0.0 0.0 0.1 16750.7 563.8 0.0 1.3 173.5 1457.1 1.6 0.7 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 1365.3 649.1 SPINK13 "HESPINTOR, LiESP6, MGC149260, SPINK5L3" ENSG00000214510 "Serine peptidase inhibitor Kazal type 13" Q1W4C9 5 148268180-148286255 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 328.8" "Group enriched" "Detected in some" 6 "Leydig cells: 39.7;Peritubular cells: 26.7" "Cancer enhanced" "Detected in some" "renal cancer: 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HeLa: 574.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036456 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA036456: AB_10673496" "unprognostic (5.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-2)" "unprognostic (6.43e-3)" "unprognostic (1.25e-3)" "unprognostic (5.01e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (4.03e-10)" "unprognostic (4.31e-2)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (2.95e-2)" 0.3 1.9 0.7 0.1 1.2 0.0 0.0 0.9 1.0 0.2 0.0 1.1 0.0 0.2 328.8 0.1 0.4 0.2 0.5 0.4 0.8 0.6 0.0 0.3 0.1 1.3 0.8 0.5 0.2 0.0 0.5 0.0 1.4 1.7 0.0 1.5 0.2 31.3 0.4 0.5 0.0 0.1 0.7 0.0 1.6 1.3 1.1 0.1 0.3 0.0 0.0 1.5 0.1 2.8 0.0 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 574.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.0 0.0 0.3 30.0 0.2 0.3 0.0 22.5 0.0 0.0 0.2 1.9 0.0 0.6 1.1 0.1 0.4 0.1 0.6 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.9 1.0 0.4 0.8 1.3 0.8 1.4 0.7 1.1 2.8 0.1 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 0.0 0.1 39.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 1.4 2.8 0.0 26.7 0.1 0.5 0.0 0.1 0.0 0.6 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPINK14 SPINK5L2 ENSG00000196800 "Serine peptidase inhibitor Kazal type 14 (putative)" Q6IE38 5 148169733-148175398 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.8;intestine: 1.0;liver: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "OE19: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 65: Brain - Ion transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" "unprognostic (4.98e-2)" "unprognostic (3.44e-1)" "unprognostic (1.94e-2)" "unprognostic (2.96e-2)" "unprognostic (5.69e-1)" "unprognostic (1.48e-3)" 0.0 0.0 2.3 0.0 1.3 0.0 0.8 0.5 3.3 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.6 0.0 1.1 0.1 0.0 1.6 1.0 0.0 0.0 0.0 0.0 0.2 2.5 0.1 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.3 0.5 3.3 0.9 0.6 1.6 1.0 2.5 1.0 1.4 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 SPINK2 HUSI-II ENSG00000128040 "Serine peptidase inhibitor Kazal type 2" P20155 4 56809860-56821742 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "epididymis: 5310.4" "Group enriched" "Detected in many" 10 "Early spermatids: 1217.2;Late spermatids: 1399.4;Spermatocytes: 1989.6" "Group enriched" "Detected in some" 5 "lung cancer: 1.3;testis cancer: 4.6;thyroid cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "NK-cell: 146.4" "Lineage enriched" "Detected in many" 7 "NK-cells: 146.4" "Cell line enriched" "Detected in some" 4 "U-266/70: 90.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB020824, HPA026813" Enhanced "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB020824: , HPA026813: AB_1857446" "unprognostic (5.56e-3)" "unprognostic (3.60e-1)" "unprognostic (7.54e-2)" "unprognostic (2.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.60e-1)" "prognostic favorable (2.82e-4)" "unprognostic (9.83e-2)" "unprognostic (6.62e-2)" "unprognostic (9.40e-3)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (4.10e-3)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.87e-2)" 0.5 0.1 0.1 1.1 0.2 13.5 1.3 0.1 0.6 1.3 1.8 2.8 1.9 0.3 5310.4 0.2 0.3 0.1 7.4 0.2 0.2 0.3 0.2 0.2 4.7 0.3 0.3 0.4 0.1 0.0 4.2 0.0 0.2 3.5 2.1 0.0 2.0 240.7 1.8 0.5 3.1 0.3 0.2 1.7 3.0 346.1 0.3 3.9 0.6 2.3 4.8 0.5 4.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.7 2.9 18.0 0.5 0.0 0.0 0.0 0.0 4.5 0.0 6.0 0.3 3.0 0.0 0.0 0.2 0.7 0.0 0.4 0.0 0.0 0.0 0.2 0.0 90.5 0.4 0.0 0.0 0.0 0.0 4.4 0.0 1.1 0.5 0.1 0.6 9.1 5.1 5.4 1.4 10.5 11.1 21.6 0.9 146.4 0.0 0.8 0.3 5.4 0.1 0.2 0.1 0.6 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.1 0.2 0.0 0.0 0.0 7.2 2.0 14.2 1.8 1.8 0.0 0.2 0.6 3.4 0.0 0.2 0.0 0.0 0.0 2.5 1.4 0.0 0.0 1217.2 0.2 0.1 1.6 1.8 32.4 0.3 0.0 0.3 0.8 0.5 0.2 1.3 0.3 0.0 0.0 0.1 0.0 0.2 10.4 0.0 0.0 3.6 1399.4 37.9 2.5 12.4 0.0 1.6 1.5 1.0 0.0 0.1 0.0 13.1 24.5 35.2 9.5 0.4 0.3 0.3 0.0 13.1 0.4 1.9 1989.6 149.9 0.1 0.3 0.0 16.8 0.0 2.6 2.6 SPINK4 "MGC133107, PEC-60" ENSG00000122711 "Serine peptidase inhibitor Kazal type 4" O60575 9 33218365-33248567 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 980.5" "Cell type enriched" "Detected in some" 14 "Intestinal goblet cells: 8017.1" "Group enriched" "Detected in many" 20 "colorectal cancer: 237.5;pancreatic cancer: 269.7;stomach cancer: 111.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 1.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.8" "Group enriched" "Detected in some" 12 "HMC-1: 175.7;OE19: 480.7" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in single" HPA007286 Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Secreted to digestive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Vesicles" Nucleoplasm "HPA007286: AB_1080083" "unprognostic (3.49e-2)" "unprognostic (2.32e-1)" "prognostic favorable (8.85e-5)" "unprognostic (3.09e-4)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (9.66e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-1)" "unprognostic (3.25e-1)" "unprognostic (2.42e-3)" 1.4 0.6 0.0 84.2 0.0 0.6 0.1 0.7 0.3 0.0 0.1 639.5 263.4 1.8 0.0 0.1 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.1 0.1 0.0 0.9 2.1 0.9 0.0 0.1 0.0 980.5 92.1 0.1 0.5 0.2 0.1 638.1 42.2 0.0 0.2 1.4 0.3 0.0 0.1 0.0 0.0 0.0 17.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 11.7 27.8 1.1 0.0 0.0 175.7 0.0 0.0 0.0 0.4 0.5 0.0 0.1 4.1 0.3 0.0 3.9 0.4 2.3 0.0 480.7 0.4 0.0 0.0 0.2 0.0 0.5 0.4 1.4 15.2 3.1 0.0 0.1 14.2 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.3 0.1 1.4 0.3 0.0 1.8 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.3 0.0 0.0 0.0 21.7 0.1 0.0 0.0 0.0 0.0 5.5 12.5 0.1 0.0 56.5 0.0 0.2 1.0 0.1 0.0 0.6 88.2 0.0 0.0 0.0 0.0 0.0 43.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8017.1 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.9 0.0 0.5 0.1 0.1 106.8 0.0 0.1 0.2 541.4 0.0 0.0 129.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.1 191.5 0.2 SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 338.5;esophagus: 1015.0;skin 1: 318.2;vagina: 582.6" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 1622.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 14.7;HeLa: 22.7;Karpas-707: 19.3;SuSa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" NA NA 43000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" 1.1 0.3 0.0 0.5 0.1 0.0 17.5 0.0 0.2 338.5 0.0 4.8 0.3 0.6 0.3 1015.0 0.4 1.8 1.7 0.1 0.0 0.8 0.4 2.0 0.1 0.1 0.1 0.3 0.8 1.0 2.0 2.4 0.2 1.3 10.6 0.0 145.0 0.5 1.8 318.2 0.6 0.4 0.0 0.3 5.0 1.6 0.1 9.1 2.2 1.1 292.9 0.7 582.6 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 1.8 0.0 0.0 14.7 0.0 1.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.3 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.0 0.9 19.3 0.0 2.1 0.0 0.0 2.6 2.0 0.3 0.0 0.0 0.0 0.0 5.7 2.8 0.0 0.6 0.0 0.0 6.6 4.6 0.0 0.0 0.0 0.1 0.0 0.0 5.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 5.7 9.6 45.4 0.3 0.2 53.7 1.5 331.1 102.4 0.0 4.2 3.4 1.2 34.3 115.6 0.0 0.0 1.9 0.0 177.9 0.0 0.2 11.0 2.5 0.7 12.9 4.2 0.0 0.7 1.3 2.1 2.6 17.9 4.8 1.3 0.0 7.9 0.2 0.1 0.0 0.8 33.8 16.2 0.8 2.1 3.8 0.6 0.7 3.6 2.8 0.0 0.0 0.0 2.0 1.2 7.6 60.3 0.0 3.7 0.7 0.0 0.0 9.4 0.0 0.0 0.2 2.4 1.3 4.6 1622.6 64.4 1.5 1.1 1.0 97.9 2.7 SPINK6 "BUSI2, MGC21394, UNQ844" ENSG00000178172 "Serine peptidase inhibitor Kazal type 6" Q6UWN8 5 148202794-148215137 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 5.7;lymphoid tissue: 4.9;salivary gland: 6.9;vagina: 10.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.5;Hofbauer cells: 2.8;Oligodendrocyte precursor cells: 1.0;Prostatic glandular cells: 5.2" "Group enriched" "Detected in many" 6 "cervical cancer: 21.4;head and neck cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 74 "HeLa: 3708.0;SiHa: 2339.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA011039 Uncertain "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "HPA011039: AB_2668412" "unprognostic (2.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.65e-1)" "unprognostic (4.87e-2)" "prognostic favorable (7.16e-4)" "unprognostic (2.49e-2)" "unprognostic (4.04e-1)" "unprognostic (1.80e-2)" "unprognostic (2.09e-2)" "unprognostic (2.22e-2)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" 0.6 0.2 0.1 0.0 0.7 0.0 0.2 3.0 1.1 5.7 0.1 1.7 0.0 0.0 1.2 2.4 0.0 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.5 0.3 6.9 0.0 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.4 4.9 0.0 0.1 0.0 0.6 10.1 2.1 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.5 3708.0 4.0 0.0 0.6 0.0 0.0 28.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 2339.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.3 40.8 0.2 0.1 0.0 0.7 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 3.0 1.1 0.4 0.1 0.6 0.4 0.9 0.1 0.4 2.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.8 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.4 0.0 5.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 256.8;esophagus: 620.4;vagina: 614.0" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 49.2" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" NA NA 230000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.3 256.8 0.1 0.1 0.0 0.1 0.1 620.4 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.7 0.0 0.3 0.1 0.0 0.0 140.1 0.0 0.2 9.3 0.1 0.1 0.1 0.1 4.2 0.1 0.2 4.7 0.1 0.1 115.9 0.6 614.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 0.0 0.0 0.0 0.0 0.0 4.5 SPINK8 ENSG00000229453 "Serine peptidase inhibitor Kazal type 8 (putative)" P0C7L1 3 48306842-48328341 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 11.5;breast: 44.1" "Group enriched" "Detected in some" 5 "Breast glandular cells: 22.1;Breast myoepithelial cells: 9.9" "Group enriched" "Detected in some" 10 "breast cancer: 8.6;glioma: 9.6;prostate cancer: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "eosinophil: 1.3;neutrophil: 1.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.7" "Cell line enriched" "Detected in some" 60 "SK-BR-3: 73.2" "Region enriched" "Detected in many" 9 "hippocampal formation: 73.7" "Low region specificity" "Detected in all" HPA053151 Uncertain "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA053151: AB_2682059" "prognostic unfavorable (8.47e-4)" "unprognostic (1.98e-1)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" 0.0 0.0 2.2 0.0 2.2 11.5 44.1 2.6 4.5 0.0 0.4 0.0 0.1 0.0 2.5 2.8 0.2 0.0 0.0 3.0 1.8 0.0 0.0 0.1 0.0 2.9 1.5 0.0 0.4 0.0 0.1 0.2 2.6 0.5 0.0 0.3 2.1 0.3 0.0 0.1 0.0 0.0 1.8 0.6 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.1 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 73.2 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 2.2 2.2 2.6 4.5 3.0 1.8 2.9 1.5 2.6 1.8 2.6 2.9 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 22.1 9.9 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 1.1 0.1 0.0 1.2 0.0 0.0 2.7 1.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 2.0 0.0 0.0 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.6 SPINK9 ENSG00000204909 "Serine peptidase inhibitor Kazal type 9" Q5DT21 5 148321203-148339852 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 16.0;Alveolar cells type 2: 27.9;Club cells: 14.9;granulocytes: 10.1;Respiratory ciliated cells: 14.6" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 12.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 24.4;U-266/84: 26.9" "Low region specificity" "Detected in single" HPA038288 Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA 24000 "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Vesicles" "HPA038288: AB_10795400" "unprognostic (1.84e-1)" "unprognostic (4.87e-3)" "unprognostic (2.88e-1)" "unprognostic (9.02e-2)" "unprognostic (5.49e-3)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "unprognostic (1.91e-2)" "unprognostic (3.93e-1)" "unprognostic (2.01e-1)" "unprognostic (3.99e-2)" "unprognostic (1.90e-1)" 1.5 3.2 17.1 3.0 13.7 6.5 0.5 19.2 26.6 0.6 5.0 2.0 2.2 2.6 1.9 2.2 1.0 1.4 2.0 14.6 10.6 1.8 1.6 1.1 2.6 10.0 6.1 1.8 1.1 0.5 0.1 3.2 10.8 2.5 1.7 10.3 1.5 0.5 3.8 3.4 2.4 0.5 2.6 1.9 2.4 4.2 11.5 3.2 1.5 0.1 1.6 0.9 0.0 28.0 15.4 2.6 2.9 3.4 0.7 1.2 2.8 3.5 0.2 0.3 0.5 5.3 10.8 3.4 24.4 0.1 2.0 3.5 0.9 0.7 1.0 6.1 1.4 7.7 8.3 2.7 0.3 2.9 2.6 0.2 0.7 0.5 0.1 2.0 0.0 2.5 4.9 18.3 0.4 9.6 2.5 4.7 13.7 5.5 5.0 3.9 3.4 4.0 1.0 10.0 6.3 7.9 3.0 8.6 2.8 8.6 14.0 3.0 5.9 4.4 14.1 3.9 4.5 11.1 26.9 4.0 2.6 2.1 6.2 12.4 1.8 1.0 1.1 1.0 1.4 0.8 1.3 1.4 0.4 1.9 1.8 1.8 6.6 3.9 2.2 1.9 0.9 0.1 17.1 13.7 19.2 26.6 14.6 10.6 10.0 6.1 10.8 2.6 11.5 28.0 0.1 16.0 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.4 0.0 14.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 1.9 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.1 10.1 0.1 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 2.2 0.4 0.0 0.1 0.0 0.3 14.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.7 0.0 0.0 0.2 SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1254.0;Distal enterocytes: 477.6;Proximal enterocytes: 514.5;Syncytiotrophoblasts: 1673.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 323.2;HaCaT: 377.6;hTCEpi: 264.0;RT4: 308.2;SK-BR-3: 558.8;T-47d: 267.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" 2.8 0.7 0.9 16.4 1.5 1.4 34.7 5.0 1.3 42.8 6.4 108.7 159.9 13.2 78.9 255.5 33.6 38.0 1.3 0.9 2.0 79.9 3.5 47.6 6.4 2.8 3.2 2.4 69.2 132.9 31.4 144.9 2.2 52.3 89.2 0.4 162.7 31.4 0.6 148.9 138.2 4.3 1.7 6.9 88.3 1.8 3.2 9.9 34.7 0.4 45.5 57.1 90.1 2.3 124.8 1.0 0.0 0.9 0.1 0.0 323.2 2.3 3.0 4.0 2.4 195.3 202.4 0.3 141.2 0.4 3.6 377.6 30.8 181.9 2.4 1.0 10.6 5.6 3.3 10.8 2.2 21.9 93.9 0.3 264.0 3.9 16.5 3.4 14.7 12.1 2.7 1.1 0.2 96.5 0.9 16.6 37.4 207.6 17.7 12.6 0.0 24.9 179.3 308.2 79.8 3.9 9.3 558.8 15.7 56.9 267.7 16.1 0.0 0.2 2.0 1.2 0.5 1.2 24.5 0.8 0.8 16.3 1.1 0.0 19.7 14.3 0.4 15.9 0.8 8.4 3.0 1.4 32.4 6.0 1.1 0.3 25.9 5.5 18.1 4.0 0.5 7.6 0.9 1.5 5.0 1.3 0.9 2.0 2.8 3.2 2.2 1.7 3.2 2.3 0.8 57.7 14.7 0.0 7.6 76.0 96.7 220.0 55.8 0.1 96.2 63.5 0.5 105.8 207.3 134.3 0.0 1254.0 1.4 477.6 25.4 429.4 0.8 63.3 14.2 6.9 147.3 4.8 0.5 255.1 105.1 10.4 106.5 155.6 10.2 1.9 0.4 0.5 135.4 0.0 0.5 169.4 221.8 10.0 23.8 1.1 3.7 19.8 14.2 0.0 68.6 0.0 0.0 0.0 0.0 309.8 375.2 0.0 2.1 135.7 514.5 44.2 46.6 0.3 0.0 0.1 12.6 0.6 5.9 93.2 87.9 1673.8 6.6 0.1 182.7 222.3 SPINT3 HKIB9 ENSG00000101446 "Serine peptidase inhibitor, Kunitz type 3" P49223 20 45512461-45515622 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.8;seminal vesicle: 10.7" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 1.5;Endometrial ciliated cells: 1.4;Glandular and luminal cells: 4.0;Suprabasal keratinocytes: 2.3;Urothelial cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA026852 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Endometrium - Transcription" "HPA026852: AB_2732434" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.4 SPINT4 "C20orf137, dJ601O1.1" ENSG00000149651 "Serine peptidase inhibitor, Kunitz type 4" Q6UDR6 20 45722347-45725830 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 255 "epididymis: 278.8" "Cell type enriched" "Detected in single" 9 "Rod photoreceptor cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" HPA046703 Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA046703: AB_2732530" "unprognostic (3.61e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 278.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.4 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPOCK1 "SPOCK, testican-1, TIC1" ENSG00000152377 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1" Q08629 5 136975298-137598379 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 172.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 252.8;Inhibitory neurons: 349.9;Muller glia cells: 243.8;Oligodendrocyte precursor cells: 273.4;Oligodendrocytes: 913.1;Peritubular cells: 150.1" "Cancer enriched" "Detected in all" 7 "prostate cancer: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 573.1;hTERT-RPE1: 1112.8;HUVEC TERT2: 594.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007450, HPA026770" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA007450: AB_10603116, HPA026770: " "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.08e-4)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.72e-4)" "unprognostic (9.09e-3)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.77e-5)" "prognostic unfavorable (9.40e-4)" "unprognostic (1.26e-1)" "unprognostic (2.21e-1)" "unprognostic (1.90e-2)" 29.7 41.4 67.9 4.1 116.3 0.3 19.0 129.2 99.5 25.6 9.9 24.9 1.2 44.2 34.3 6.1 18.6 18.6 54.2 100.5 50.9 24.3 0.2 2.9 0.6 80.7 84.5 4.8 5.5 13.7 9.9 9.3 89.8 65.6 3.2 48.7 7.6 25.5 17.5 9.3 4.6 30.7 78.4 8.5 9.1 21.7 102.6 7.5 9.4 7.1 0.4 11.4 21.7 172.9 4.6 0.9 299.4 0.4 573.1 116.0 0.4 100.6 90.0 207.7 115.9 0.0 0.6 0.4 0.2 206.7 53.3 4.4 1.4 70.3 65.3 17.8 0.6 0.2 16.7 0.0 4.0 0.0 0.4 203.8 28.5 128.6 23.2 1112.8 594.4 0.2 0.0 0.4 60.5 0.5 0.0 0.2 19.1 0.0 28.4 0.0 0.2 0.0 140.3 9.4 3.7 14.4 49.9 0.8 0.1 35.6 0.4 1.2 98.9 294.0 10.6 102.1 28.5 0.1 0.1 0.1 159.4 4.4 136.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 67.9 116.3 129.2 99.5 100.5 50.9 80.7 84.5 89.8 78.4 102.6 172.9 2.0 0.0 0.0 91.7 0.0 1.8 1.6 5.8 0.0 9.7 0.4 0.4 58.8 1.5 0.4 22.0 2.1 0.4 0.0 0.2 1.9 0.6 12.0 4.2 37.9 8.4 35.0 0.0 252.8 1.4 0.3 58.8 0.0 2.9 0.0 0.1 1.1 0.0 0.9 8.4 349.9 0.1 16.2 1.2 3.0 9.5 17.4 1.6 7.2 17.8 2.3 243.8 0.0 273.4 913.1 2.0 0.1 150.1 0.1 40.9 0.0 3.1 0.9 7.3 13.1 11.6 16.4 7.4 7.1 0.7 1.4 0.1 0.4 0.0 0.3 3.2 SPOCK2 "KIAA0275, testican-2" ENSG00000107742 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2" Q92563 10 72059034-72089032 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.1;lymphoid tissue: 114.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 288.4;Bipolar cells: 116.5;dendritic cells: 86.4;Inhibitory neurons: 81.1;Microglial cells: 75.9;NK-cells: 90.6;T-cells: 195.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 117.5;MAIT T-cell: 198.8;memory CD4 T-cell: 115.9;memory CD8 T-cell: 93.5;naive CD4 T-cell: 87.8;naive CD8 T-cell: 89.4;T-reg: 174.3" "Lineage enriched" "Detected in all" 8 "T-cells: 198.8" "Group enriched" "Detected in some" 7 "Hep G2: 50.2;SCLC-21H: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044605 Enhanced "Secreted to blood" NA NA 34000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "HPA044605: AB_10965991" "prognostic favorable (4.05e-4)" "unprognostic (3.11e-3)" "unprognostic (2.92e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.18e-2)" "unprognostic (9.04e-2)" "prognostic favorable (4.72e-4)" "prognostic unfavorable (7.19e-4)" "unprognostic (4.53e-3)" "unprognostic (2.29e-1)" "unprognostic (1.46e-3)" "unprognostic (5.59e-2)" "unprognostic (5.49e-2)" "unprognostic (3.19e-3)" "unprognostic (2.24e-2)" 9.4 46.6 152.6 44.5 108.0 58.1 3.8 160.4 143.2 4.2 2.8 7.6 9.2 4.0 3.1 3.3 6.2 15.3 10.0 117.4 150.1 68.0 2.7 86.5 67.3 212.1 157.7 7.1 1.6 2.0 44.0 3.4 220.1 4.7 5.4 33.4 3.3 5.6 5.1 1.8 32.3 4.4 127.9 29.1 13.6 25.1 207.3 114.4 10.4 6.7 45.3 9.9 3.8 95.6 0.2 0.4 0.3 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 8.2 0.3 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.8 0.2 1.4 50.2 1.6 0.4 1.2 0.1 0.4 0.0 0.0 0.2 0.1 2.7 0.1 0.8 0.0 0.3 0.9 0.3 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.3 68.2 4.1 0.1 1.5 0.4 0.3 0.0 1.9 0.2 0.0 0.3 0.3 0.1 0.7 1.7 7.3 0.3 0.1 0.2 0.6 0.4 0.2 117.5 1.2 198.8 23.6 115.9 93.5 0.3 18.3 87.8 89.4 13.5 14.4 0.4 3.5 174.3 48.4 152.6 108.0 160.4 143.2 117.4 150.1 212.1 157.7 220.1 127.9 207.3 95.6 17.3 288.4 10.0 51.9 54.6 3.8 0.4 2.1 0.0 116.5 1.9 2.0 3.1 1.5 4.1 14.7 6.2 0.1 86.4 2.4 0.0 3.6 8.1 2.5 1.0 29.9 4.9 3.6 39.6 0.8 0.1 8.4 3.6 1.0 3.8 0.2 7.9 0.4 0.2 3.3 81.1 1.3 2.0 1.6 7.9 10.5 5.3 5.5 5.4 75.9 4.1 5.0 90.6 28.6 8.3 0.0 4.4 6.0 34.2 0.5 0.1 0.5 2.4 17.6 0.0 17.9 2.4 6.3 1.1 0.5 4.4 0.4 195.1 0.8 0.7 0.3 SPOCK3 testican-3 ENSG00000196104 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3" Q9BQ16 4 166733384-167234796 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.9;parathyroid gland: 175.0;prostate: 73.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 1010.6;Oligodendrocyte precursor cells: 399.1;Oligodendrocytes: 1851.1" "Cancer enhanced" "Detected in many" "prostate cancer: 7.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 1.8" "Group enriched" "Detected in many" 12 "dendritic cells: 1.8;monocytes: 1.2" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.2;hTERT-RPE1: 6.5;PC-3: 2.7;RH-30: 7.1;SCLC-21H: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.54e-2)" "unprognostic (8.69e-2)" "unprognostic (2.90e-3)" "unprognostic (1.20e-1)" "unprognostic (4.09e-4)" "unprognostic (3.75e-1)" "unprognostic (1.97e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-1)" "unprognostic (3.94e-4)" "unprognostic (8.92e-2)" "unprognostic (4.18e-3)" "unprognostic (2.62e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-3)" "unprognostic (1.64e-1)" 0.3 24.7 51.4 0.6 87.2 0.1 0.3 73.0 97.3 0.9 18.7 0.9 0.8 2.9 18.8 0.2 1.1 0.3 0.3 48.4 63.8 0.2 0.4 0.4 0.5 83.2 64.9 17.4 0.7 175.0 0.3 0.0 79.4 73.9 0.5 14.3 0.3 34.9 0.2 0.0 1.3 2.8 72.8 0.4 0.7 0.5 68.4 0.3 0.2 24.0 0.3 1.7 0.2 143.9 0.0 1.6 0.2 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.4 0.1 0.2 0.0 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 6.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 2.7 0.0 7.1 0.4 0.0 1.1 2.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.5 51.4 87.2 73.0 97.3 48.4 63.8 83.2 64.9 79.4 72.8 68.4 143.9 0.0 0.0 0.0 12.7 0.1 0.0 1.5 8.1 0.0 43.7 0.0 0.0 1.6 0.0 10.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 15.0 0.0 0.2 1.6 0.0 1.3 106.7 0.0 0.1 15.7 2.0 0.0 1.3 3.2 0.0 0.0 0.1 15.2 1010.6 0.0 6.1 0.0 0.0 2.9 0.9 0.5 0.0 98.4 0.2 1.3 0.0 399.1 1851.1 0.1 0.0 0.4 0.0 3.3 0.0 0.1 6.7 6.3 0.0 0.0 2.5 0.5 0.7 0.0 0.0 0.1 0.0 55.4 0.0 0.8 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 187.1" "Cell type enhanced" "Detected in many" "dendritic cells: 427.0;Endometrial stromal cells: 256.6;Extravillous trophoblasts: 355.8;Fibroblasts: 257.7;NK-cells: 1096.8" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 255.9" "Lineage enriched" "Detected in all" 5 "T-cells: 255.9" "Group enriched" "Detected in many" 5 "HHSteC: 303.8;HSkMC: 546.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" 66.2 40.4 4.0 18.8 7.7 19.5 50.6 15.6 3.9 161.4 3.5 51.5 18.5 187.1 4.4 40.6 49.7 32.2 35.5 3.5 0.8 37.1 79.1 63.0 3.9 2.9 1.7 34.4 18.7 0.9 15.1 19.2 3.5 111.8 7.2 0.7 28.8 8.4 19.1 38.3 63.5 42.7 0.2 26.9 43.8 4.7 1.8 1.8 16.3 6.6 1.0 68.4 94.0 1.5 0.4 0.6 0.0 0.0 10.2 79.0 3.0 6.2 5.0 0.8 1.0 0.0 0.1 1.8 9.7 26.9 0.9 45.0 0.0 0.2 0.0 0.3 0.1 0.2 3.0 12.7 303.8 0.2 1.5 546.6 0.0 0.6 0.0 0.0 0.0 4.1 0.3 9.2 0.0 0.3 5.3 12.2 3.5 9.7 0.7 1.0 3.3 7.9 0.0 0.0 1.7 1.1 1.1 0.0 2.9 1.7 0.4 1.5 0.1 0.2 0.9 20.5 0.0 1.3 2.7 0.6 0.1 6.5 0.0 3.7 0.9 1.0 255.9 1.1 5.5 0.7 33.1 105.8 0.4 1.0 14.4 96.8 9.8 50.4 2.2 42.9 0.1 123.2 4.0 7.7 15.6 3.9 3.5 0.8 2.9 1.7 3.5 0.2 1.8 1.5 9.8 0.0 5.6 1.3 6.6 36.8 2.0 82.5 2.2 3.7 5.1 3.8 4.0 24.3 43.0 1.8 0.0 3.4 427.0 9.7 1.9 3.8 0.2 12.7 256.6 5.7 13.8 4.0 8.4 1.3 355.8 257.7 10.7 6.6 6.3 0.2 15.4 40.4 12.8 0.0 0.6 9.7 73.2 5.8 15.4 0.5 29.8 9.5 26.6 6.5 9.2 0.9 1096.8 0.5 0.7 1.5 6.7 9.4 64.0 15.8 16.3 28.3 32.6 0.4 6.6 22.5 89.9 0.2 0.5 21.3 21.5 38.9 100.8 8.1 7.9 13.2 SPP1 "BNSP, BSPI, ETA-1, OPN" ENSG00000118785 "Secreted phosphoprotein 1" P10451 4 87975650-87983426 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Biomineralization, Cell adhesion" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 2424.4;kidney: 3587.6;placenta: 2791.9" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 60702.5" "Group enriched" "Detected in all" 4 "glioma: 1690.9;renal cancer: 1385.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "neutrophil: 24.8" "Lineage enriched" "Detected in single" 249 "granulocytes: 24.8" "Cell line enhanced" "Detected in many" "EFO-21: 4825.8;Hep G2: 2469.7;RPTEC TERT1: 10348.3" "Region enhanced" "Detected in all" "pons and medulla: 316.8" "Low region specificity" "Detected in all" "HPA027540, HPA027541" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 114000000 73000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "HPA027540: AB_10600222, HPA027541: AB_10601446" "unprognostic (4.74e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.13e-3)" "unprognostic (2.04e-1)" "unprognostic (2.31e-2)" "unprognostic (6.96e-3)" "prognostic unfavorable (2.84e-6)" "unprognostic (2.46e-3)" "unprognostic (7.86e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (4.31e-2)" "unprognostic (2.55e-1)" "unprognostic (7.19e-2)" "unprognostic (1.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.63e-2)" 113.1 24.4 276.0 59.5 490.3 1.0 70.2 652.0 736.4 27.5 265.0 44.9 9.5 131.2 9.8 4.8 52.8 2424.4 37.0 301.6 417.1 3587.6 35.6 18.8 9.1 813.2 645.3 9.9 292.0 19.2 20.6 2791.9 781.8 15.7 7.6 745.5 88.7 22.1 16.0 2.7 14.4 38.3 472.6 9.2 11.0 11.7 633.1 8.4 8.3 0.4 5.7 25.0 6.0 855.0 2.2 144.0 19.1 1.1 0.0 0.2 0.3 5.6 4.4 1.4 9.1 0.6 0.2 0.2 4825.8 2.3 371.5 1.4 0.0 0.0 3.1 11.2 0.0 0.0 1.8 2469.7 0.3 6.8 5.1 0.5 0.3 34.9 0.1 118.8 4.2 0.2 0.1 10.8 1.3 0.2 1.2 21.3 227.5 0.3 0.0 2.4 0.5 1189.8 10348.3 1.8 1.1 0.9 0.3 0.8 339.1 441.9 0.5 5.2 0.3 11.5 27.1 0.4 25.8 0.9 7.9 13.9 436.3 1.1 457.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 276.0 490.3 652.0 736.4 301.6 417.1 813.2 645.3 781.8 472.6 633.1 855.0 35.7 3.2 4.7 5.2 34.0 1.5 5.2 0.1 1.2 46.6 1767.7 22.4 17.9 1584.2 0.3 2183.1 27.1 335.6 6.9 0.0 1003.7 7273.8 0.1 61.2 25.2 367.9 0.0 2.7 1.4 71.7 294.5 48.9 0.0 154.2 0.0 1.7 5.7 5.0 60702.5 785.7 9.9 0.0 0.0 57.4 7.7 1.0 0.9 247.7 1.8 99.3 69.2 3862.9 0.0 4.5 532.1 215.4 0.0 0.0 0.1 0.4 0.0 5594.0 1.6 169.7 0.0 0.9 21.6 0.5 0.2 1.1 1.0 667.8 30.0 0.4 0.0 9.9 SPP2 SPP24 ENSG00000072080 "Secreted phosphoprotein 2" Q13103 2 234050679-234077134 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4373 "liver: 519.1" "Cell type enriched" "Detected in some" 20 "Hepatocytes: 258.7" "Cancer enriched" "Detected in some" 112 "liver cancer: 65.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 480000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "prognostic favorable (2.33e-6)" "unprognostic (7.02e-3)" "unprognostic (9.62e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 519.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 5.3 0.3 0.6 0.0 0.7 0.0 0.1 5.1 0.0 5.0 258.7 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 SPTY2D1OS SPTY2D1-AS1 ENSG00000247595 "SPTY2D1 opposite strand" A0A0U1RRN3 11 18588781-18610255 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 34 "testis: 487.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 7.5;Distal tubular cells: 23.5;Endometrial stromal cells: 6.9;Granulosa cells: 18.4;Proximal tubular cells: 14.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 4.4;HeLa: 7.6;Hep G2: 4.5" "Low region specificity" "Detected in many" "Secreted in male reproductive system" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.07e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-3)" "unprognostic (5.14e-2)" "unprognostic (6.61e-2)" "unprognostic (9.32e-2)" "unprognostic (4.44e-7)" "unprognostic (1.75e-1)" "unprognostic (1.39e-2)" "unprognostic (7.83e-2)" "unprognostic (5.36e-2)" "unprognostic (6.50e-3)" "unprognostic (5.41e-4)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" 0.9 1.8 1.4 1.4 1.5 0.9 2.7 3.2 2.9 1.7 3.8 1.5 0.2 2.0 3.7 1.3 1.6 1.2 1.5 1.4 2.6 2.0 0.7 0.8 0.7 2.2 1.7 2.4 1.1 0.9 1.6 1.2 1.9 2.0 2.3 3.5 1.7 1.4 1.5 14.1 1.0 1.3 0.9 1.2 0.9 487.5 1.8 0.4 1.7 0.3 0.8 0.9 1.3 2.7 0.5 4.4 1.7 2.3 1.5 2.3 2.1 0.3 0.5 0.9 1.0 3.4 1.2 0.8 0.2 0.4 0.9 0.9 0.0 0.0 0.0 1.3 1.6 0.5 7.6 4.5 0.2 0.6 1.3 0.9 0.3 0.2 1.0 1.1 0.9 0.0 1.2 0.3 0.3 1.6 0.1 1.6 1.2 1.1 2.7 0.1 0.5 0.3 1.8 1.8 0.4 0.2 1.6 0.1 0.0 0.6 0.9 0.0 0.9 1.6 1.3 0.8 0.1 0.0 0.2 0.0 0.6 0.9 1.1 0.2 0.3 0.6 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.5 0.2 0.1 0.1 0.3 0.2 1.4 1.5 3.2 2.9 1.4 2.6 2.2 1.7 1.9 0.9 1.8 2.7 2.8 3.2 3.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.5 6.0 0.0 0.0 1.3 5.5 0.0 1.0 1.5 0.0 23.5 3.2 0.0 4.9 6.9 1.1 0.0 0.0 0.0 5.0 1.1 1.8 0.0 3.9 0.0 18.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 14.3 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.5 0.8 2.1 0.0 0.0 SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 111.4" "Group enriched" "Detected in some" 4 "Distal tubular cells: 86.1;Proximal tubular cells: 202.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 17.5;HBEC3-KT: 8.9;hTERT-HME1: 12.4;SuSa: 14.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 17.1;hippocampal formation: 17.9;olfactory bulb: 7.5;pons: 8.0" "Secreted to blood" NA NA 2650000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.78e-2)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.81e-2)" "unprognostic (2.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (5.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.37e-3)" "unprognostic (9.78e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" 111.4 0.1 8.7 0.1 9.2 0.4 4.1 8.6 24.2 0.0 7.2 0.1 0.0 1.3 0.6 0.2 0.2 0.1 2.8 8.1 11.5 26.4 2.3 0.6 0.2 8.6 13.9 0.0 20.7 0.4 0.0 17.7 26.6 0.0 0.0 1.7 6.9 0.5 2.0 0.0 0.3 0.1 8.0 0.4 0.5 0.2 9.6 3.0 20.2 8.8 0.1 0.0 0.0 9.9 0.0 0.5 0.8 0.0 3.0 1.2 0.0 0.0 0.1 0.1 1.2 17.5 0.0 0.7 0.3 0.0 0.3 0.0 0.0 8.9 1.6 0.0 0.0 4.7 0.0 0.1 1.8 0.0 0.0 5.7 0.9 0.3 12.4 0.2 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 2.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 1.7 14.6 0.0 0.2 0.3 0.0 5.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.7 9.2 8.6 24.2 8.1 11.5 8.6 13.9 26.6 8.0 9.6 9.9 1.4 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 3.0 0.7 0.9 28.9 0.0 0.0 25.8 0.0 0.0 0.1 0.0 86.1 0.4 0.0 0.5 0.3 0.6 0.0 0.0 0.0 19.1 0.0 1.7 0.0 2.5 0.0 0.0 0.7 0.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 13.7 0.0 0.0 1.2 4.9 4.1 0.0 0.1 2.5 0.0 0.0 0.0 0.1 0.0 202.2 0.0 0.5 0.0 2.4 0.9 0.0 1.8 0.0 0.0 0.4 1.0 0.1 0.0 0.1 SRGN "PPG, PRG, PRG1" ENSG00000122862 Serglycin P10124 10 69088103-69104805 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Biomineralization" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 8096.7" "Cell type enhanced" "Detected in many" "dendritic cells: 2922.2;granulocytes: 2343.1;Kupffer cells: 1789.9;Langerhans cells: 6618.2;Macrophages: 3639.1;monocytes: 3188.2;Plasma cells: 1740.9;T-cells: 2235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 5714.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 5714.1" "Cell line enhanced" "Detected in many" "HL-60: 4442.1;NB-4: 2549.7;THP-1: 4346.8;TIME: 2609.1;U-937: 3546.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000759 Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA000759: AB_1079675" "unprognostic (3.61e-2)" "unprognostic (1.62e-2)" "unprognostic (2.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (4.50e-2)" "unprognostic (1.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.63e-1)" "unprognostic (8.22e-2)" "unprognostic (5.80e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.65e-1)" "unprognostic (2.32e-2)" "unprognostic (4.07e-2)" "unprognostic (4.08e-2)" 404.6 114.9 48.8 799.8 50.5 8096.7 136.4 55.5 99.6 93.2 70.1 101.8 77.9 63.5 25.9 91.0 96.8 316.4 111.9 48.2 67.8 98.3 239.4 347.3 437.2 82.4 59.3 30.7 68.4 131.6 62.1 355.6 67.8 58.9 118.9 15.5 40.1 57.4 37.5 18.9 111.4 219.4 65.5 362.8 95.0 18.3 64.7 228.9 72.7 117.1 314.6 508.3 46.1 71.0 5.3 43.0 0.2 0.4 768.1 749.7 1.2 94.9 63.9 235.1 283.5 0.1 18.2 9.1 117.4 4.1 134.4 1.1 0.0 20.6 799.9 535.7 0.4 87.1 29.8 0.3 312.7 4442.1 914.9 306.8 1.1 641.5 39.2 223.8 1227.8 13.3 82.5 419.9 1239.9 0.2 18.7 2549.7 0.7 0.1 84.6 2.4 2.3 446.7 0.6 6.0 0.3 0.8 2.3 0.6 16.0 0.0 2.2 4346.8 2609.1 187.9 12.9 3.8 20.1 486.4 508.4 57.3 112.2 3546.9 1.2 2349.8 1105.3 2730.6 474.9 774.6 313.4 73.5 228.5 362.8 583.0 39.0 125.5 268.4 5714.1 962.8 693.6 631.9 392.6 1590.5 48.8 50.5 55.5 99.6 48.2 67.8 82.4 59.3 67.8 65.5 64.7 71.0 1081.4 112.2 198.1 0.7 592.0 175.9 12.5 38.3 8.6 1.1 16.0 28.2 21.2 21.5 57.5 33.1 0.0 10.2 2922.2 2.9 0.0 4.2 4.1 4.6 15.0 566.8 1.8 277.8 0.2 9.8 10.2 87.9 70.3 6.6 2343.1 0.4 636.1 22.1 847.1 0.0 0.5 1.7 0.0 1789.9 6618.2 8.4 7.5 3639.1 556.7 80.6 3188.2 1.4 1292.5 0.0 0.2 1.3 1.2 18.0 1740.9 12.2 0.3 4.7 45.6 5.0 72.3 22.8 97.5 0.9 2.2 8.7 141.8 14.2 2235.9 1.2 5.5 18.1 SRPX ETX1 ENSG00000101955 "Sushi repeat containing protein X-linked" P78539 X 38149336-38220924 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 215.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 256.9;Granulosa cells: 138.9;Hepatic stellate cells: 418.7;Leydig cells: 110.3;Peritubular cells: 95.2" "Group enriched" "Detected in all" 5 "glioma: 64.2;melanoma: 70.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 49 "plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 49 "dendritic cells: 7.8" "Cell line enhanced" "Detected in many" "ASC diff: 3742.4;ASC TERT1: 827.3;HSkMC: 1258.3;HUVEC TERT2: 803.2" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "spinal cord: 12.4" "Secreted - unknown location" NA NA 140000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.35e-1)" "unprognostic (1.09e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (6.48e-2)" "unprognostic (3.83e-3)" "unprognostic (3.50e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (7.80e-13)" "unprognostic (6.94e-3)" "unprognostic (3.90e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.36e-4)" 215.2 37.2 8.2 22.4 12.8 0.1 148.0 17.8 5.9 48.6 5.2 83.0 7.9 56.1 39.6 36.6 113.4 58.1 93.3 7.0 16.7 7.4 17.7 46.6 5.0 13.2 14.2 21.4 23.9 2.7 4.6 88.9 15.4 18.3 24.8 1.6 22.9 15.3 15.6 29.2 52.6 52.9 15.1 1.7 42.5 6.7 13.8 19.2 59.1 13.6 5.3 103.8 42.9 15.4 0.3 5.0 12.1 0.2 3742.4 827.3 0.9 35.3 67.8 11.9 20.2 0.5 3.6 0.1 0.3 74.3 119.9 1.9 2.0 30.8 9.8 0.2 13.8 0.1 1.0 0.4 167.8 3.0 0.4 1258.3 2.6 114.9 58.3 132.8 803.2 1.4 0.1 0.2 130.1 1.7 0.5 0.1 10.2 1.8 26.2 0.0 43.5 6.4 0.8 2.3 2.3 2.3 1.7 0.1 170.1 31.2 0.0 0.4 349.1 82.2 42.3 108.8 103.7 0.0 0.1 0.1 239.0 3.1 106.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 0.0 0.1 8.2 12.8 17.8 5.9 7.0 16.7 13.2 14.2 15.4 15.1 13.8 15.4 28.7 3.2 1.3 17.0 0.6 15.3 2.2 2.8 7.4 0.4 2.9 8.6 14.2 0.0 0.2 1.8 0.0 3.6 2.1 2.5 0.0 0.3 0.7 1.1 35.1 67.2 0.0 2.7 1.9 0.4 5.4 256.9 1.5 0.8 0.0 138.9 418.7 2.5 6.1 0.0 2.7 5.8 0.0 11.4 15.2 4.9 110.3 1.6 74.7 1.0 0.0 0.2 0.0 2.5 0.3 0.8 1.8 95.2 0.2 1.6 0.4 0.2 0.0 0.4 26.3 4.8 54.6 0.7 2.3 1.7 7.2 7.1 1.9 21.4 0.5 0.8 SRPX2 SRPUL ENSG00000102359 "Sushi repeat containing protein X-linked 2" O60687 X 100644195-100675788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.8" "Cell type enhanced" "Detected in many" "Adipocytes: 20.9;Fibroblasts: 34.3;Granulosa cells: 21.6;Microglial cells: 37.5;Skeletal myocytes: 17.5;Urothelial cells: 49.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 282.3;ASC TERT1: 116.9;HSkMC: 103.3;HUVEC TERT2: 72.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 2.8" HPA038786 Approved "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038786: AB_10672724" "unprognostic (4.10e-2)" "unprognostic (4.55e-2)" "unprognostic (2.08e-1)" "unprognostic (3.72e-2)" "unprognostic (1.96e-1)" "unprognostic (4.21e-3)" "unprognostic (3.59e-3)" "unprognostic (5.41e-2)" "unprognostic (3.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.86e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-3)" "unprognostic (1.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.85e-1)" 31.8 7.5 3.6 6.3 4.5 0.2 20.7 1.3 2.6 11.3 8.5 7.1 1.2 6.0 0.9 17.7 7.1 3.1 12.7 2.8 5.8 13.9 5.4 13.8 0.4 4.3 5.6 8.3 2.9 0.7 2.5 9.3 3.1 6.3 1.8 0.1 4.6 3.8 3.4 3.7 5.1 4.4 2.0 12.9 4.5 1.1 7.4 0.3 4.3 4.8 1.2 16.8 10.9 2.5 11.7 1.2 2.9 0.1 282.3 116.9 0.0 26.3 19.8 8.0 25.1 1.4 17.6 0.0 1.1 15.9 7.5 0.7 0.2 13.1 8.6 0.1 0.1 0.2 0.9 2.8 29.3 0.2 0.6 103.3 0.3 27.8 0.9 24.6 72.7 0.0 0.0 0.1 27.1 0.0 0.0 0.0 3.4 0.2 0.3 0.0 2.5 0.0 11.4 37.6 0.4 0.0 0.0 0.8 0.2 6.1 0.3 0.1 36.7 13.8 12.3 10.3 0.9 0.1 0.0 0.1 18.3 0.0 8.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.5 1.3 2.6 2.8 5.8 4.3 5.6 3.1 2.0 7.4 2.5 20.9 0.0 0.6 10.1 0.3 0.4 5.0 6.5 0.6 0.0 4.8 1.8 0.9 0.0 13.7 0.0 0.0 0.2 0.0 1.9 0.0 1.6 3.6 0.6 11.2 1.6 0.0 0.0 0.4 0.0 0.4 34.3 1.1 0.4 0.0 21.6 4.6 0.2 0.9 0.0 0.2 0.1 4.1 0.3 1.6 2.7 15.8 0.3 0.0 37.5 0.0 0.0 0.0 2.0 0.1 0.8 0.0 6.0 0.2 1.6 0.0 0.1 15.5 0.0 0.0 17.5 14.6 0.2 0.1 0.6 0.4 0.5 0.3 2.6 0.4 49.1 SSC4D "S4D-SRCRB, SRCRB-S4D, SRCRB4D" ENSG00000146700 "Scavenger receptor cysteine rich family member with 4 domains" Q8WTU2 7 76389334-76409697 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.6;parathyroid gland: 7.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.0;Distal tubular cells: 3.9;Hepatocytes: 3.7;Spermatogonia: 3.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "EFO-21: 6.7;Hep G2: 9.6;SuSa: 10.7;U-2 OS: 25.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062611 Uncertain "Secreted - unknown location" NA NA 980000 "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 7: Non-specific - Mitochondria" "HPA062611: AB_2684807" "unprognostic (3.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (2.83e-6)" "prognostic unfavorable (7.08e-4)" "unprognostic (3.52e-2)" "unprognostic (3.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.49e-2)" "unprognostic (8.49e-3)" "unprognostic (3.18e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (2.59e-1)" "unprognostic (3.90e-1)" "unprognostic (2.56e-2)" "unprognostic (1.73e-2)" 0.7 0.3 0.2 0.0 0.4 0.0 0.3 0.0 0.2 0.3 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 2.6 0.4 0.1 0.0 0.2 0.2 0.7 2.2 7.0 2.6 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.1 0.0 0.5 0.0 0.0 1.0 0.0 0.3 0.0 0.8 0.2 0.0 0.0 0.1 1.0 0.5 0.0 0.0 10.7 0.2 0.0 0.0 0.0 25.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.2 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.5 1.6 0.1 0.0 0.5 0.0 0.6 0.4 1.4 1.4 2.1 0.0 0.0 11.0 0.0 0.3 0.0 0.2 3.9 1.9 0.1 0.5 0.1 0.3 0.0 0.0 1.6 1.7 1.4 0.4 0.0 0.4 0.0 0.7 1.1 3.7 2.8 1.7 1.4 0.1 0.0 0.6 0.0 0.4 0.9 0.9 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.4 0.1 0.4 0.0 0.4 0.4 1.3 0.0 0.2 0.0 0.8 0.6 0.6 3.5 1.0 0.0 0.3 0.1 0.6 0.2 0.4 SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.3;Fibroblasts: 27.0;Leydig cells: 18.0;Peritubular cells: 15.8;Skeletal myocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 26.9;BJ: 22.7;fHDF/TERT166: 27.5;hTERT-RPE1: 23.2;U-87 MG: 27.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" 13.1 2.2 2.6 3.6 4.6 0.1 8.8 3.0 2.1 23.0 1.8 33.6 1.9 39.7 3.9 5.7 17.0 12.9 17.6 1.8 2.1 3.6 1.7 9.1 1.3 3.9 2.6 14.5 1.8 0.3 17.6 1.9 4.0 8.8 2.8 1.1 3.4 12.8 3.6 5.6 8.7 20.1 2.2 11.1 9.8 2.6 3.6 2.0 3.8 2.8 0.5 10.6 15.9 2.1 0.1 1.4 0.5 0.0 3.3 26.9 0.0 22.7 5.5 3.7 4.6 0.4 0.0 1.2 0.3 27.5 1.1 0.0 0.0 0.0 1.9 0.1 0.3 5.6 1.5 0.0 5.2 0.1 9.6 12.3 0.0 5.4 0.0 23.2 0.0 0.7 0.2 0.3 0.6 0.1 0.1 0.5 0.9 0.0 0.2 0.7 1.2 0.3 2.5 0.0 2.9 0.4 0.4 0.0 0.5 0.5 0.4 1.2 7.9 1.0 1.3 1.1 3.8 0.4 0.0 0.1 27.8 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.6 3.0 2.1 1.8 2.1 3.9 2.6 4.0 2.2 3.6 2.1 3.5 3.2 0.6 4.2 0.3 1.9 0.3 0.3 0.0 5.3 0.8 1.1 2.8 0.0 0.1 0.0 2.1 0.1 0.4 0.8 1.9 0.1 0.6 1.5 19.3 3.3 0.0 0.0 1.5 0.0 0.1 27.0 2.0 0.9 0.0 0.5 2.2 0.0 1.2 3.3 1.1 0.4 0.0 1.0 3.8 1.3 18.0 2.0 1.8 2.8 0.7 2.1 0.0 0.0 0.3 0.1 0.3 15.8 0.3 0.3 4.6 0.2 0.7 1.9 0.0 32.1 6.8 0.9 1.1 0.4 1.8 0.0 0.5 0.9 1.4 0.2 SST SMST ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 449.5;intestine: 386.6;pancreas: 479.4;stomach 1: 418.0" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 1404.1;Intestinal goblet cells: 460.2" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 449.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 22.4;U-2 OS: 44.7;U-251 MG: 7.6;U-698: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" 5.5 43.0 59.9 4.6 52.1 4.2 0.5 1.3 67.8 0.6 2.5 31.8 386.6 0.7 0.1 1.6 0.4 1.1 1.3 30.6 449.5 6.2 0.3 0.3 1.5 96.9 48.1 2.4 479.4 0.0 9.3 0.1 50.3 1.3 23.8 6.3 0.1 21.6 0.1 8.9 133.3 2.8 137.8 0.2 418.0 0.2 117.2 1.1 1.0 0.0 0.0 7.3 1.8 18.7 0.0 0.0 0.8 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 44.7 0.4 7.6 0.0 2.9 11.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.9 52.1 1.3 67.8 30.6 449.5 96.9 48.1 50.3 137.8 117.2 18.7 0.0 0.0 0.0 9.1 0.5 0.0 0.0 3.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 5.5 0.0 0.1 0.0 4.3 0.0 0.0 0.3 0.3 0.5 0.1 1404.1 0.0 1.7 0.0 0.2 0.7 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 146.2 460.2 215.7 0.0 0.0 0.1 0.0 0.0 0.0 9.4 3.6 0.0 0.0 3.0 9.1 0.0 0.6 0.0 0.0 0.0 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.9 13.8 0.2 ST6GAL1 SIAT1 ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930325-187078553 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 495.9;lymphoid tissue: 148.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 237.3;Hepatic stellate cells: 258.5;Hepatocytes: 608.7;Microglial cells: 602.4" "Cancer enhanced" "Detected in all" "liver cancer: 70.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 250.6;U-266/70: 628.0;U-266/84: 887.9;U-698: 334.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" NA NA 15000000 3300000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" 24.5 12.5 27.0 50.2 26.2 15.2 32.5 29.8 24.8 61.4 33.3 38.1 13.9 16.1 5.9 13.5 27.0 17.8 36.0 25.8 33.9 60.0 495.9 30.1 101.7 44.0 37.5 10.1 8.1 45.5 9.8 18.5 50.3 48.8 45.4 2.6 39.3 14.6 12.8 8.3 29.1 18.9 44.1 67.5 28.8 3.5 39.2 66.6 64.8 20.2 148.1 28.0 8.9 48.3 4.3 5.0 20.6 17.1 1.1 0.0 36.3 1.6 3.0 1.4 2.0 1.9 2.0 250.6 19.5 0.1 8.8 10.1 132.7 15.4 1.6 11.3 7.4 10.1 0.8 119.0 1.3 22.8 75.0 1.7 28.3 0.0 11.5 19.9 77.5 24.2 52.2 20.3 5.2 8.7 17.0 14.7 49.9 11.3 7.6 38.2 0.4 8.1 9.9 0.5 36.4 4.1 1.5 26.6 64.6 29.1 38.9 16.8 32.6 0.2 3.3 0.6 2.1 628.0 887.9 334.0 0.5 45.4 84.7 22.6 8.9 3.6 46.9 16.2 42.9 87.9 51.3 39.7 14.2 83.3 80.4 58.4 4.2 26.9 29.3 11.9 43.8 58.7 27.0 26.2 29.8 24.8 25.8 33.9 44.0 37.5 50.3 44.1 39.2 48.3 34.6 44.8 27.4 13.4 110.0 4.0 13.8 68.0 4.6 0.3 5.1 4.1 26.2 75.8 55.9 237.3 0.0 0.3 26.3 20.7 0.0 17.1 0.5 8.9 5.0 56.0 94.1 24.8 47.2 0.9 3.5 3.7 7.7 16.1 10.8 7.3 258.5 608.7 20.3 0.0 31.5 10.9 34.6 61.3 16.4 1.1 0.3 18.2 7.2 602.4 17.2 0.1 26.8 145.3 2.8 6.0 17.8 0.7 124.3 103.6 0.6 0.5 39.8 1.1 0.0 2.2 6.8 0.0 0.5 0.8 1.6 0.7 28.4 0.3 37.3 39.0 STATH STR ENSG00000126549 Statherin P02808 4 69995966-70002570 "Plasma proteins, Predicted secreted proteins, Transporters" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 925 "salivary gland: 9143.2" "Group enriched" "Detected in some" 9 "Breast glandular cells: 9.8;Early spermatids: 2.8" "Group enriched" "Detected in some" 14 "head and neck cancer: 3.5;lung cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044569 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Mammary glandular cells - Lactation" "HPA044569: AB_10966146" "unprognostic (2.00e-2)" 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 2.1 9.8 0.0 5.6 0.8 0.0 0.1 0.0 0.0 9143.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 9.8 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STC1 STC ENSG00000159167 "Stanniocalcin 1" P52823 8 23841929-23854806 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 64.3" "Cell type enhanced" "Detected in many" "Adipocytes: 162.2;Collecting duct cells: 97.5;Endometrial ciliated cells: 84.0;Endothelial cells: 242.0;Glandular and luminal cells: 301.5;Theca cells: 214.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 348.4;hTEC/SVTERT24-B: 201.7;U-251 MG: 145.4;U-87 MG: 623.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB018625, HPA023918" Approved "Secreted in other tissues" NA NA 240000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "CAB018625: AB_2197536, HPA023918: AB_1857566" "unprognostic (1.18e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "prognostic unfavorable (6.44e-5)" "prognostic unfavorable (6.32e-4)" "unprognostic (2.84e-2)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.82e-2)" "unprognostic (1.44e-2)" "unprognostic (7.61e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.23e-6)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.79e-1)" "unprognostic (1.19e-3)" "unprognostic (8.95e-3)" 44.7 3.1 2.1 2.6 1.4 0.1 26.2 2.0 5.8 49.4 13.8 7.4 1.7 32.4 0.6 7.0 5.9 14.8 25.7 4.1 3.9 17.9 4.0 10.5 0.7 4.5 4.3 2.8 13.7 10.5 28.9 29.1 4.5 9.3 1.9 8.3 10.3 7.3 2.6 3.0 2.9 7.5 3.4 0.2 10.4 0.2 4.7 1.5 64.3 6.4 1.3 44.4 10.2 2.9 1.5 1.3 1.9 0.0 13.0 14.3 0.3 20.6 348.4 6.7 31.5 0.1 0.0 0.1 30.0 6.8 116.6 1.1 0.8 5.1 58.0 2.2 0.4 0.1 0.0 0.0 0.9 0.0 0.5 65.1 0.0 201.7 0.5 96.4 2.8 0.0 0.6 0.5 28.8 0.0 0.0 0.1 8.4 0.0 1.0 0.0 0.3 0.0 11.7 0.0 0.8 0.0 31.4 2.1 2.1 2.3 21.3 0.4 27.0 82.3 3.1 1.6 145.4 0.0 0.1 0.1 623.7 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.4 2.0 5.8 4.1 3.9 4.5 4.3 4.5 3.4 4.7 2.9 162.2 3.2 13.6 0.0 0.2 22.7 2.4 15.7 0.0 3.1 75.3 8.0 3.3 32.9 3.7 97.5 0.0 0.9 0.0 0.8 0.0 37.0 0.1 84.0 42.7 242.0 0.0 0.0 0.2 0.2 6.1 67.9 2.6 301.5 1.3 0.2 23.2 0.0 2.5 8.4 0.3 0.0 0.0 0.3 25.8 0.2 5.0 1.5 17.8 0.0 0.0 0.9 0.0 0.0 0.1 6.7 0.0 0.0 1.2 7.6 0.0 0.1 0.5 2.1 0.0 0.5 7.4 0.0 0.0 0.3 20.6 1.9 2.6 214.5 1.0 9.6 STC2 STC-2 ENSG00000113739 "Stanniocalcin 2" O76061 5 173314723-173328447 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 143.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 278.3;Breast myoepithelial cells: 119.6;Extravillous trophoblasts: 59.5" "Cancer enriched" "Detected in all" 6 "breast cancer: 91.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 1019.9;T-47d: 940.0;U-138 MG: 382.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA045372 Approved Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA 19000000 "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "HPA045372: AB_10961040" "prognostic favorable (7.40e-5)" "unprognostic (2.40e-2)" "unprognostic (9.03e-3)" "unprognostic (1.21e-1)" "unprognostic (1.89e-3)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (3.07e-5)" "unprognostic (5.28e-3)" "unprognostic (6.12e-3)" "unprognostic (1.53e-1)" "unprognostic (2.13e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.17e-8)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.56e-2)" "unprognostic (5.06e-2)" "unprognostic (7.93e-3)" 7.4 1.7 0.7 2.4 0.9 0.0 143.6 2.2 3.1 13.2 1.9 4.8 0.6 3.0 0.3 2.0 2.0 6.4 9.9 3.0 1.8 3.6 0.8 11.3 1.1 5.0 6.4 0.7 32.6 3.3 1.7 28.0 3.7 4.8 0.6 7.7 1.0 6.7 4.4 12.8 2.7 21.2 1.3 11.5 3.4 0.7 2.9 0.2 9.1 4.9 0.3 4.7 3.0 3.0 52.5 15.3 2.7 13.0 47.9 20.5 133.8 234.5 239.4 59.1 115.0 74.4 36.7 0.0 33.4 139.8 298.2 21.5 33.8 72.0 102.5 0.1 18.9 0.0 26.7 50.2 311.3 15.8 4.3 43.6 117.9 133.3 7.9 274.4 16.7 42.4 2.4 0.1 1019.9 41.6 0.7 0.7 7.9 23.4 73.2 0.3 36.5 27.4 0.0 3.9 35.6 9.6 10.3 1.1 42.5 10.4 940.0 15.9 151.5 382.8 1.3 229.1 49.2 42.0 24.3 10.5 74.6 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 2.2 3.1 3.0 1.8 5.0 6.4 3.7 1.3 2.9 3.0 6.9 0.0 0.0 0.0 0.4 5.0 0.2 4.9 0.6 11.1 278.3 119.6 27.1 0.0 0.6 0.0 0.0 37.0 2.4 0.4 0.0 31.6 0.6 9.5 1.0 25.3 7.2 0.0 0.2 13.1 59.5 16.7 0.0 16.1 0.0 0.0 3.6 0.0 5.2 0.0 0.2 0.2 0.0 0.0 4.8 1.0 23.0 0.5 10.6 1.0 0.0 0.9 0.0 0.0 0.1 7.8 0.0 0.4 0.0 0.8 0.0 4.5 0.2 2.4 0.0 2.3 24.6 0.7 0.8 0.5 6.3 21.9 1.0 0.9 0.4 0.5 SVBP "CCDC23, MGC45441" ENSG00000177868 "Small vasohibin binding protein" Q8N300 1 42807052-42817397 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 149.0;Erythroid cells: 135.4;Spermatocytes: 158.0;Spermatogonia: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008507 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Secreted to blood" Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA008507: AB_2072066" "prognostic favorable (6.33e-4)" "unprognostic (2.68e-2)" "unprognostic (2.91e-1)" "unprognostic (4.60e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.15e-2)" "unprognostic (3.35e-3)" "unprognostic (1.59e-2)" "unprognostic (6.73e-3)" "unprognostic (2.16e-1)" "unprognostic (5.37e-3)" "unprognostic (1.17e-3)" "unprognostic (7.07e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" 34.7 15.1 36.4 13.7 37.7 43.1 29.9 39.1 49.9 30.9 33.6 29.3 11.6 24.9 26.2 17.7 27.2 15.2 24.7 37.1 38.4 25.6 19.1 17.4 23.0 38.2 37.3 36.3 12.1 22.1 30.6 20.6 37.5 20.3 15.7 22.6 15.9 15.4 28.0 17.7 19.9 19.2 38.2 22.1 19.0 52.9 37.1 48.3 19.0 23.5 23.5 23.9 24.8 40.3 25.9 12.9 75.2 26.9 30.9 48.3 37.2 21.5 18.1 28.8 29.7 22.8 20.2 29.1 23.5 28.6 22.6 18.3 14.3 23.7 35.2 53.6 23.7 54.5 12.1 43.9 25.6 41.3 35.2 31.2 37.4 16.2 15.4 29.7 29.1 56.0 46.2 14.3 35.3 12.0 41.5 50.8 40.8 23.7 14.5 30.9 55.8 19.2 29.9 25.3 45.5 40.4 26.8 14.9 31.7 76.9 11.3 120.1 22.7 25.4 28.1 19.6 35.6 14.9 19.1 20.7 16.1 27.5 24.4 60.5 40.2 76.5 26.8 40.8 23.5 56.4 46.5 32.3 39.2 59.8 42.8 37.2 70.3 37.3 43.8 33.0 115.7 24.7 36.4 37.7 39.1 49.9 37.1 38.4 38.2 37.3 37.5 38.2 37.1 40.3 46.2 9.6 6.3 0.0 25.0 0.0 33.0 0.0 23.9 6.2 33.1 53.1 0.0 28.6 9.3 20.2 2.1 53.8 20.0 19.5 54.8 51.7 149.0 32.2 34.6 32.3 18.2 135.4 0.0 24.5 66.0 36.6 14.3 18.2 11.4 22.8 42.8 45.6 70.4 6.7 0.0 19.6 0.0 51.8 0.0 61.6 42.9 48.4 0.0 0.0 70.2 33.1 29.9 0.0 0.0 43.1 21.7 53.8 16.9 21.9 20.5 43.2 7.3 15.5 59.2 28.1 28.4 158.0 153.8 21.4 0.0 61.6 21.4 24.1 23.6 31.1 TAC1 "NKNA, NPK, TAC2" ENSG00000006128 "Tachykinin precursor 1" P20366 7 97732084-97740472 "Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 55.6;lymphoid tissue: 46.1" "Cell type enriched" "Detected in some" 7 "Inhibitory neurons: 99.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-266/70: 22.8" "Region enhanced" "Detected in all" "basal ganglia: 560.0" "Region enriched" "Detected in all" 10 "basal ganglia: 388.8" HPA014429 Enhanced "Secreted to blood" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA014429: AB_1857722" "unprognostic (9.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (2.08e-1)" "unprognostic (7.95e-2)" "unprognostic (3.24e-1)" "unprognostic (1.70e-2)" "unprognostic (3.21e-2)" "unprognostic (1.70e-1)" "unprognostic (1.69e-1)" "unprognostic (3.86e-2)" 2.1 8.6 7.3 10.9 34.2 0.0 2.1 2.0 12.1 0.6 1.9 9.8 8.3 0.8 1.6 0.0 1.0 6.6 1.4 6.1 45.1 7.3 0.3 0.5 0.0 53.2 55.6 0.2 0.6 0.5 1.5 0.0 21.5 1.3 3.6 3.4 6.8 2.1 0.3 1.2 10.3 7.5 16.4 46.1 3.0 0.4 23.9 0.1 7.4 0.0 0.0 1.5 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 34.2 2.0 12.1 6.1 45.1 53.2 55.6 21.5 16.4 23.9 6.4 0.1 0.0 0.0 2.9 0.5 0.4 0.1 0.0 0.0 0.0 0.4 0.6 0.3 7.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 2.0 1.0 0.0 0.0 0.0 1.2 0.0 0.0 13.2 0.0 9.7 0.0 0.0 0.0 0.0 0.1 0.0 99.4 5.4 0.0 0.0 0.4 0.1 0.3 0.1 0.0 1.9 0.0 0.0 0.0 1.5 3.4 0.5 0.0 0.0 0.0 4.2 0.3 9.1 0.0 0.0 0.0 1.1 1.3 0.2 2.1 0.0 0.1 0.0 0.4 0.0 0.5 0.9 TAC3 "LncZBTB39, LncZBTB39-1:2, NK3, NKB, NKNB, ZNEUROK1" ENSG00000166863 "Tachykinin precursor 3" Q9UHF0 12 57010000-57028883 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "placenta: 431.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Extravillous trophoblasts: 19.6;Inhibitory neurons: 40.0;Syncytiotrophoblasts: 18.3" "Cancer enriched" "Detected in many" 7 "urothelial cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "K-562: 14.4;SuSa: 13.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA045919 Supported Supported Approved Vesicles "Secreted in female reproductive system" NA NA 130000 "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA045919: AB_10960533" "unprognostic (4.53e-2)" "unprognostic (1.97e-2)" "unprognostic (8.41e-2)" "unprognostic (3.00e-2)" "unprognostic (3.61e-2)" "unprognostic (1.76e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "unprognostic (1.34e-1)" "unprognostic (2.03e-1)" "unprognostic (5.28e-2)" "unprognostic (4.71e-14)" "unprognostic (1.58e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" 0.1 0.3 15.2 2.5 11.0 1.0 0.1 5.2 16.5 0.1 5.6 3.8 3.0 0.3 0.0 0.1 0.0 0.3 0.1 11.2 25.1 0.1 0.1 0.1 0.2 16.8 7.7 0.2 0.6 0.0 0.7 431.7 7.7 0.2 1.5 6.1 0.0 0.0 0.2 0.5 6.5 4.8 27.3 0.1 13.1 1.8 6.2 0.5 0.1 0.0 0.4 3.1 0.3 9.8 0.0 0.1 0.0 0.4 0.0 0.0 1.2 0.0 1.1 0.3 0.0 1.6 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 14.4 0.3 0.0 0.0 0.0 0.2 1.6 0.5 0.0 0.0 0.0 0.0 0.0 1.5 2.1 0.6 0.0 0.8 0.0 13.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 11.0 5.2 16.5 11.2 25.1 16.8 7.7 7.7 27.3 6.2 9.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 13.9 0.0 1.4 0.0 0.0 0.1 0.0 0.4 0.1 1.2 2.7 0.5 0.0 19.6 2.6 0.0 0.1 0.0 4.3 0.7 0.0 2.2 0.0 40.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.5 2.8 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 2.6 1.0 0.0 0.0 18.3 0.0 0.0 1.8 0.0 TAC4 "HK-1, PPT-C, Pptc" ENSG00000176358 "Tachykinin precursor 4" Q86UU9 17 49838309-49848017 "Predicted secreted proteins" "Hypotensive agent" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 5.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Excitatory neurons: 2.3;Inhibitory neurons: 1.2;Oligodendrocyte precursor cells: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.5;BEWO: 5.9;CACO-2: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.49e-2)" "unprognostic (8.14e-2)" "unprognostic (8.95e-2)" "unprognostic (1.71e-1)" "unprognostic (6.24e-2)" "unprognostic (8.15e-2)" "unprognostic (5.61e-2)" "unprognostic (6.05e-3)" "unprognostic (3.19e-1)" "unprognostic (2.00e-1)" "unprognostic (4.52e-2)" "unprognostic (4.69e-3)" "unprognostic (8.19e-5)" "unprognostic (8.69e-2)" "unprognostic (2.23e-1)" "unprognostic (7.98e-2)" "unprognostic (1.92e-1)" 0.2 0.3 0.5 0.3 0.4 0.7 0.1 1.7 1.1 0.2 0.8 0.1 0.2 0.2 0.0 0.6 0.0 0.3 1.1 0.4 0.0 0.1 1.7 0.3 0.4 0.3 0.1 0.1 0.1 0.1 5.0 0.2 0.2 0.3 0.0 0.3 0.4 0.0 0.2 1.7 0.2 0.3 0.0 0.7 0.3 0.3 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.3 0.0 2.5 0.0 0.4 0.0 0.0 5.9 0.0 0.0 0.0 0.0 3.5 0.2 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.7 0.1 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.2 0.3 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.3 0.0 0.5 0.2 0.1 0.1 0.2 0.6 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 1.7 1.1 0.4 0.0 0.3 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TAFA1 "FAM19A1, TAFA-1" ENSG00000183662 "TAFA chemokine like family member 1" Q7Z5A9 3 68004247-68545621 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 15.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 6 "T-cells: 20.7" "Cell line enriched" "Detected in single" 10 "REH: 1.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 12.5;cerebral cortex: 35.6;hippocampal formation: 33.0" HPA013407 Approved "Secreted in brain" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "HPA013407: AB_1848386" "unprognostic (5.19e-2)" "unprognostic (4.64e-3)" "unprognostic (1.97e-2)" "unprognostic (1.86e-2)" "unprognostic (7.95e-2)" "unprognostic (6.40e-2)" "unprognostic (3.42e-3)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (2.41e-1)" "unprognostic (1.41e-2)" "unprognostic (7.87e-2)" "unprognostic (1.35e-3)" "unprognostic (2.11e-1)" "unprognostic (1.99e-1)" "unprognostic (3.50e-4)" "unprognostic (5.77e-2)" 0.2 1.1 4.1 0.3 7.3 0.0 0.0 0.0 13.9 0.0 1.6 0.2 1.3 0.2 1.1 0.1 0.0 0.7 0.1 13.9 9.1 0.3 0.3 0.1 0.6 12.4 1.0 0.0 0.0 0.0 0.4 0.0 15.4 1.4 0.1 0.3 0.1 3.8 0.1 0.0 0.2 0.3 0.4 0.4 0.1 0.2 8.6 0.0 0.1 0.2 0.2 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 20.7 0.0 15.9 0.0 16.6 11.1 0.0 0.0 11.9 15.9 0.4 3.7 0.0 0.1 8.4 3.3 4.1 7.3 0.0 13.9 13.9 9.1 12.4 1.0 15.4 0.4 8.6 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TAFA3 "FAM19A3, TAFA-3" ENSG00000184599 "TAFA chemokine like family member 3" Q7Z5A8 1 112720419-112727235 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "adrenal gland: 15.5;retina: 51.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.3;BJ hTERT+: 4.7;HEL: 1.8;U-87 MG: 1.7" "Region enriched" "Detected in single" 21 "olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA055927 Approved "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA055927: AB_2682972" "unprognostic (9.96e-2)" "unprognostic (4.30e-1)" "unprognostic (3.36e-2)" "unprognostic (5.63e-4)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.66e-1)" "unprognostic (3.40e-2)" "unprognostic (1.13e-1)" "unprognostic (6.43e-2)" "unprognostic (1.32e-1)" "unprognostic (9.82e-2)" "unprognostic (2.51e-1)" "unprognostic (5.14e-6)" "unprognostic (2.10e-4)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-1)" 0.3 15.5 1.3 0.1 0.7 0.0 0.2 1.2 0.7 0.1 0.4 0.0 0.0 0.1 0.7 0.2 0.3 0.1 0.1 0.5 0.6 0.1 0.0 0.0 0.4 1.9 3.0 0.6 0.0 0.0 0.3 0.1 1.0 0.3 0.0 51.2 0.1 0.2 0.0 0.2 0.0 0.1 0.9 0.0 0.0 8.0 2.6 0.1 0.3 0.0 0.0 0.1 0.2 0.8 1.3 0.2 0.1 0.0 0.0 0.3 0.3 0.1 4.7 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.8 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.6 0.6 0.1 0.2 0.0 0.0 0.0 1.7 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.7 1.2 0.7 0.5 0.6 1.9 3.0 1.0 0.9 2.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 TAFA4 "FAM19A4, TAFA-4" ENSG00000163377 "TAFA chemokine like family member 4" Q96LR4 3 68731766-68953297 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 14.9;brain: 11.6;retina: 11.1;stomach 1: 4.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.8;NTERA-2: 9.2;SCLC-21H: 1.0;SuSa: 2.5" "Region enriched" "Detected in many" 5 "thalamus: 13.5" "Low region specificity" "Detected in many" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "unprognostic (1.92e-1)" "unprognostic (9.97e-3)" "unprognostic (2.28e-1)" "unprognostic (8.19e-3)" "unprognostic (8.78e-2)" "unprognostic (2.00e-2)" "unprognostic (3.01e-2)" "unprognostic (1.22e-1)" "unprognostic (3.66e-2)" "unprognostic (8.06e-2)" "unprognostic (2.50e-1)" 0.0 14.9 4.8 0.2 5.0 0.0 0.0 3.8 3.0 0.0 0.4 0.4 0.0 0.0 0.0 0.2 0.0 1.2 0.0 1.4 7.9 0.1 0.0 0.1 0.0 4.5 9.4 0.4 0.0 0.0 0.7 0.3 4.3 0.9 0.0 11.1 0.0 0.1 0.0 0.0 0.2 0.2 3.2 0.0 4.9 1.0 11.6 0.0 0.0 0.0 0.0 0.1 0.0 7.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 5.0 3.8 3.0 1.4 7.9 4.5 9.4 4.3 3.2 11.6 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAFA5 "FAM19A5, TAFA-5" ENSG00000219438 "TAFA chemokine like family member 5" Q7Z5A7 22 48489553-48850912 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 85.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Fibroblasts: 1.1" "Cancer enhanced" "Detected in all" "glioma: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 17.3;HEK 293: 13.6;Hep G2: 32.1;NTERA-2: 12.7;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025629 Approved "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB025629: " "unprognostic (2.86e-1)" "unprognostic (2.98e-1)" "unprognostic (3.42e-2)" "unprognostic (2.19e-1)" "unprognostic (3.57e-1)" "unprognostic (1.80e-1)" "unprognostic (2.82e-3)" "unprognostic (2.41e-2)" "unprognostic (6.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.26e-1)" "unprognostic (9.31e-3)" "unprognostic (2.64e-2)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.94e-2)" 2.7 1.3 50.3 0.8 40.6 0.0 2.0 37.0 51.8 19.7 15.0 8.4 1.0 8.1 4.7 0.9 5.2 2.0 2.5 53.9 43.0 2.4 2.7 2.1 0.4 55.2 85.9 12.1 2.4 4.3 7.0 0.1 51.1 6.8 0.2 3.6 4.9 3.2 1.5 5.4 3.3 0.7 41.5 0.3 2.9 3.3 49.6 1.2 0.8 1.7 0.1 4.0 4.9 28.2 0.0 1.3 2.5 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 17.3 0.1 0.1 1.3 0.0 0.0 0.0 13.6 0.0 0.2 32.1 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.3 12.7 0.6 0.0 0.6 0.0 7.4 0.0 0.0 7.2 0.2 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 40.6 37.0 51.8 53.9 43.0 55.2 85.9 51.1 41.5 49.6 28.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBL2 "DKFZP43N024, WBSCR13, WS-betaTRP" ENSG00000106638 "Transducin beta like 2" Q9Y4P3 7 73567537-73578791 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.2" "Group enriched" "Detected in all" 7 "Early spermatids: 398.2;Late spermatids: 515.4;Spermatocytes: 345.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007477, HPA051533" Supported Cytosol "Secreted in male reproductive system" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA007477: AB_1080214, HPA051533: AB_2681523" "unprognostic (9.04e-2)" "unprognostic (6.61e-3)" "unprognostic (4.24e-2)" "unprognostic (1.10e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.24e-3)" "unprognostic (7.50e-2)" "unprognostic (2.87e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.88e-5)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" 4.9 9.1 1.7 5.3 1.8 1.6 4.2 2.8 5.4 4.6 2.7 4.7 5.4 4.5 8.3 5.4 4.3 2.7 4.0 1.9 1.7 4.2 5.9 5.5 1.9 1.7 1.6 4.8 16.4 5.6 3.2 4.4 1.8 4.4 5.5 4.0 11.0 4.3 2.9 4.9 4.3 4.6 1.6 3.1 6.4 44.2 1.7 2.3 4.9 1.5 3.2 3.6 4.5 1.8 22.1 27.5 8.7 12.6 19.9 18.2 10.2 26.9 18.4 9.3 17.1 40.9 22.0 18.4 5.4 21.7 19.5 15.9 18.2 9.5 19.4 6.8 10.8 6.6 11.8 26.3 28.5 13.3 22.4 11.4 15.0 28.7 22.1 16.7 10.2 2.4 26.0 12.6 14.7 20.2 13.2 10.7 8.7 23.8 18.1 8.6 14.6 38.8 10.5 16.0 8.4 14.3 25.8 65.8 16.9 10.1 17.2 5.7 18.7 17.1 8.8 17.1 25.7 25.8 18.0 20.0 23.3 15.3 21.3 16.8 11.1 4.9 6.3 7.3 5.9 3.0 5.0 5.2 13.6 4.1 5.9 3.7 1.4 8.8 7.4 10.2 6.5 8.1 1.7 1.8 2.8 5.4 1.9 1.7 1.7 1.6 1.8 1.6 1.7 1.8 8.6 25.6 9.3 3.3 8.1 4.6 14.5 17.3 4.0 10.8 10.8 6.3 4.7 11.5 13.5 5.5 8.4 45.2 6.5 12.7 1.9 26.1 398.2 11.3 14.9 12.6 9.5 6.3 4.1 30.1 54.6 17.3 7.7 11.6 14.0 13.9 10.0 14.7 27.4 3.3 4.5 16.8 6.1 9.4 3.8 515.4 23.6 17.5 7.2 4.7 17.3 8.1 10.3 4.5 4.1 22.6 13.7 26.7 19.9 17.1 14.6 5.1 9.8 13.4 6.6 13.8 15.1 345.8 27.9 7.8 3.7 43.4 5.0 17.0 15.8 9.0 TCN1 "TC1, TCI" ENSG00000134827 "Transcobalamin 1" P20061 11 59852800-59866489 "Plasma proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "salivary gland: 776.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 52.0;Cholangiocytes: 62.9;Club cells: 94.9;Exocrine glandular cells: 372.3;Glandular and luminal cells: 84.7;Urothelial cells: 61.0" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 124.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 149 "basophil: 2374.2" "Lineage enriched" "Detected in many" 1592 "granulocytes: 2374.2" "Cell line enriched" "Detected in some" 21 "OE19: 159.0" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 4000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "prognostic favorable (1.90e-4)" "unprognostic (1.17e-1)" "unprognostic (5.89e-2)" "unprognostic (3.61e-3)" "unprognostic (2.49e-2)" "unprognostic (5.28e-3)" "unprognostic (4.52e-3)" "unprognostic (3.11e-3)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (9.07e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.56e-8)" "unprognostic (2.50e-1)" "unprognostic (8.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" 0.1 0.2 0.0 0.7 0.0 190.7 5.4 0.0 0.2 31.7 0.0 0.2 9.6 3.1 0.0 23.0 1.4 173.8 0.1 0.0 0.0 0.1 0.4 1.4 0.3 0.0 0.0 0.0 5.3 108.5 0.2 0.5 0.0 1.2 0.8 0.0 776.3 0.0 0.1 0.9 1.0 0.0 0.0 4.5 76.3 0.3 0.0 1.3 0.0 0.0 0.9 15.5 10.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 2.2 0.0 0.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 159.0 7.5 0.0 0.2 0.0 1.5 0.0 0.0 0.0 7.3 0.0 1.6 0.0 0.0 3.0 0.1 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 2374.2 0.0 0.3 0.0 0.1 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.4 15.9 0.1 1.4 0.1 0.3 4.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 19.2 52.0 0.0 0.0 21.9 4.2 0.2 62.9 94.9 23.9 0.0 0.0 0.5 0.3 0.0 23.7 0.4 2.2 8.0 0.4 0.0 0.0 0.1 372.3 0.0 0.1 3.6 84.7 0.0 0.0 0.0 0.3 0.2 0.0 0.1 1.2 12.2 0.6 0.3 0.0 0.3 0.9 0.0 0.0 0.7 0.0 0.0 0.5 0.0 46.5 0.0 0.0 0.1 5.0 0.0 0.3 11.7 0.0 0.0 0.0 2.5 0.0 0.0 6.0 0.1 0.0 0.5 0.0 0.2 61.0 TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Hepatic stellate cells: 137.4;Kupffer cells: 144.1;Proximal enterocytes: 563.6;Proximal tubular cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.8;intermediate monocyte: 66.5;non-classical monocyte: 24.4" "Lineage enriched" "Detected in many" 8 "monocytes: 66.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 117.6;HUVEC TERT2: 142.6;Karpas-707: 184.0;RPTEC TERT1: 70.7;TIME: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" NA NA 19000000 "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" 49.6 30.6 24.6 16.0 24.1 5.5 37.9 25.5 30.6 25.9 27.1 23.4 23.6 28.7 20.3 8.6 21.5 50.1 28.7 22.7 25.3 115.8 17.3 37.7 35.3 27.1 26.1 14.8 12.1 8.6 15.1 18.6 27.7 16.0 27.8 11.1 13.2 45.4 6.0 9.0 59.5 36.8 25.5 46.7 17.4 21.9 29.7 6.4 26.4 13.7 10.0 22.0 14.7 25.3 0.2 9.5 41.8 0.2 24.6 117.6 1.4 3.1 30.9 8.0 13.1 4.6 21.2 0.6 45.7 6.2 0.7 1.5 3.7 2.2 2.5 0.0 2.3 0.2 1.2 2.0 58.5 0.6 33.7 19.8 2.5 6.1 5.1 8.8 142.6 0.0 0.8 184.0 12.7 0.1 0.1 3.3 16.4 11.7 1.0 4.9 6.0 64.2 70.7 1.1 14.4 1.9 0.3 0.6 12.0 2.8 0.4 2.0 85.3 26.4 3.5 3.3 1.3 5.1 1.4 0.2 9.5 1.7 0.6 0.0 43.8 0.0 0.1 66.5 0.7 0.0 0.8 0.4 7.9 0.0 0.3 0.6 1.4 0.0 24.4 1.5 0.2 18.8 24.6 24.1 25.5 30.6 22.7 25.3 27.1 26.1 27.7 25.5 29.7 25.3 105.0 3.2 3.9 3.9 3.7 5.2 2.2 4.7 0.6 8.0 7.1 5.1 6.5 27.1 13.7 12.9 20.9 0.4 0.5 70.9 7.9 7.8 1.1 3.5 5.4 64.6 6.7 0.8 0.2 6.0 0.8 19.5 5.1 6.2 4.5 23.4 137.4 5.6 45.9 1.7 1.9 28.6 4.1 144.1 9.4 1.4 10.5 53.8 23.2 8.4 8.8 7.4 0.0 5.5 1.7 5.1 50.2 9.8 13.5 2.0 563.6 125.8 2.8 29.1 13.1 0.9 5.5 1.0 12.6 0.5 5.3 0.4 2.2 5.6 21.0 2.7 TDGF1 "CR, CR-1, CRIPTO, Cripto-1" ENSG00000241186 "Teratocarcinoma-derived growth factor 1" P13385 3 46574534-46582457 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.4;lymphoid tissue: 20.9" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 121.3" "Cancer enriched" "Detected in many" 4 "testis cancer: 27.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 25.7;NTERA-2: 110.6;SuSa: 66.3" "Group enriched" "Detected in many" 5 "cerebellum: 11.2;pons and medulla: 8.7" "Low region specificity" "Detected in single" HPA051928 Uncertain Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Vesicles Cytosol "HPA051928: " "unprognostic (7.84e-3)" "unprognostic (2.00e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.93e-1)" "unprognostic (3.61e-1)" "unprognostic (1.72e-2)" "unprognostic (6.77e-2)" "unprognostic (1.74e-1)" "unprognostic (8.76e-3)" "unprognostic (2.01e-1)" "unprognostic (2.10e-2)" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" 0.4 3.4 2.4 0.5 1.9 0.3 0.3 2.1 4.8 0.7 1.4 2.6 0.7 1.0 2.0 0.1 0.1 0.6 0.6 1.8 1.7 23.4 1.3 0.4 0.4 2.1 1.8 7.7 0.4 0.1 0.1 0.2 2.2 0.4 4.6 0.4 1.0 0.3 1.5 0.3 0.5 1.2 1.7 20.9 2.7 0.5 3.1 15.1 0.8 1.5 0.1 0.2 0.1 1.9 0.1 0.2 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 1.8 0.0 0.2 0.0 0.0 25.7 0.2 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.2 110.6 4.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 66.3 0.1 0.1 1.8 0.2 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.7 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.9 0.3 0.1 0.1 0.0 0.0 2.4 1.9 2.1 4.8 1.8 1.7 2.1 1.8 2.2 1.7 3.1 1.9 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.5 0.0 0.0 0.0 0.9 121.3 0.2 5.0 0.3 0.1 8.2 2.4 0.0 0.0 0.0 0.0 0.3 8.2 0.2 0.0 14.3 0.4 1.4 0.1 0.0 0.0 5.5 0.0 0.0 0.0 1.0 0.3 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.3 0.6 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.1 17.7 6.1 0.0 TECTA "DFNA12, DFNA8, DFNB21" ENSG00000109927 "Tectorin alpha" O75443 11 121101243-121191490 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Astrocytes: 5.2;Cone photoreceptor cells: 4.2;Early spermatids: 5.6;Excitatory neurons: 9.9;Hepatic stellate cells: 8.9;Inhibitory neurons: 7.2;Oligodendrocyte precursor cells: 5.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.1;SH-SY5Y: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018870 Approved "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA018870: AB_1857879" "unprognostic (1.12e-3)" "unprognostic (2.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.45e-2)" "unprognostic (4.30e-2)" "unprognostic (3.11e-1)" "unprognostic (3.00e-2)" "unprognostic (3.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.39e-6)" "unprognostic (1.22e-1)" "unprognostic (4.15e-3)" "unprognostic (6.97e-3)" "unprognostic (1.12e-1)" "unprognostic (3.28e-2)" "unprognostic (4.19e-2)" 0.3 0.5 1.6 0.2 2.1 0.2 0.3 1.0 1.6 0.3 1.5 0.5 0.1 0.3 0.6 0.1 0.3 0.3 1.1 1.3 2.0 0.5 0.4 0.4 0.1 1.5 1.4 0.7 0.3 0.8 1.3 0.2 1.5 0.5 0.1 1.1 0.3 0.5 0.8 0.1 0.2 0.2 0.9 0.3 0.3 0.9 1.6 0.2 0.7 0.4 0.1 0.3 0.2 1.9 0.0 0.0 1.1 0.5 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.7 1.7 0.1 0.0 0.1 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 1.0 1.6 1.3 2.0 1.5 1.4 1.5 0.9 1.6 1.9 0.5 3.2 0.5 5.2 0.1 0.0 0.1 0.0 0.0 1.8 0.2 0.3 1.9 1.5 0.6 0.0 4.2 0.0 0.2 0.0 0.0 0.2 5.6 0.6 0.3 0.5 0.0 0.0 9.9 0.4 0.1 0.4 0.0 0.3 0.0 0.6 8.9 0.6 0.1 0.0 7.2 0.0 0.0 0.3 0.0 2.7 0.3 0.2 0.0 1.0 0.2 0.9 0.0 5.0 2.8 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.2 0.7 0.0 1.9 0.4 0.9 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 TECTB ENSG00000119913 "Tectorin beta" Q96PL2 10 112283400-112305038 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late spermatids: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted in other tissues" NA NA "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.14e-2)" "unprognostic (2.84e-2)" "unprognostic (9.75e-3)" "unprognostic (1.65e-1)" "unprognostic (1.32e-2)" "unprognostic (5.54e-2)" "unprognostic (2.80e-2)" "unprognostic (8.10e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TEPP ENSG00000159648 "Testis, prostate and placenta expressed" Q6URK8 16 57976435-57988116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 14.2" "Group enriched" "Detected in many" 12 "Early spermatids: 317.5;Late spermatids: 440.1" "Group enriched" "Detected in some" 4 "thyroid cancer: 3.2;urothelial cancer: 1.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "naive CD8 T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA062092 Enhanced "Secreted in male reproductive system" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "HPA062092: AB_2684679" "unprognostic (4.86e-2)" "unprognostic (2.72e-1)" "unprognostic (4.12e-2)" "unprognostic (2.56e-2)" "unprognostic (1.79e-2)" "unprognostic (8.04e-2)" "unprognostic (3.67e-1)" "unprognostic (2.40e-2)" "unprognostic (2.74e-1)" "unprognostic (2.48e-1)" "unprognostic (1.52e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.46e-1)" "unprognostic (3.97e-3)" "unprognostic (2.59e-1)" 0.1 0.4 0.3 0.0 0.3 0.0 0.2 0.1 0.4 0.5 0.1 0.1 0.0 0.2 0.2 0.4 0.3 0.0 0.4 0.3 0.4 0.2 0.0 0.5 0.0 0.3 0.3 0.4 0.2 0.0 0.1 0.0 0.2 0.4 0.0 0.2 0.3 0.4 0.0 0.2 0.1 0.0 0.1 0.1 0.0 14.2 0.4 0.1 2.2 0.0 0.1 0.8 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.9 0.0 1.1 0.8 0.0 0.2 1.1 1.7 0.0 0.1 0.0 0.1 0.6 0.4 0.3 0.3 0.1 0.4 0.3 0.4 0.3 0.3 0.2 0.1 0.4 0.2 0.5 12.8 5.9 0.0 0.2 0.1 8.2 24.4 2.2 0.1 1.0 8.6 30.4 1.5 8.7 1.8 0.0 2.7 0.5 0.0 0.0 0.0 317.5 0.4 0.1 1.4 0.0 0.0 0.2 0.6 4.1 1.4 0.0 0.2 2.5 0.2 2.5 0.0 0.5 0.0 0.1 0.0 4.1 0.0 0.6 440.1 3.7 0.3 1.8 0.0 0.0 0.8 0.0 0.5 0.1 0.1 0.0 0.4 0.0 1.6 0.0 0.0 3.0 1.1 0.0 0.2 3.1 2.7 3.3 0.3 0.0 1.1 1.7 2.9 0.0 3.6 TEX101 "CT131, MGC4766, SGRG, SPATA44, TES101RP" ENSG00000131126 "Testis expressed 101" Q9BY14 19 43401496-43418597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 117.7" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 909.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebral cortex: 21.5" "Immune cell enriched" "Detected in single" 557 "basophil: 55.7" "Lineage enriched" "Detected in single" 557 "granulocytes: 55.7" "Cell line enhanced" "Detected in single" "THP-1: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA041915, HPA042513" Enhanced "Secreted in male reproductive system" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA041915: AB_10795268, HPA042513: AB_10795507" "unprognostic (2.50e-2)" "unprognostic (5.67e-4)" "unprognostic (2.64e-1)" "unprognostic (6.89e-2)" "unprognostic (1.87e-1)" "unprognostic (5.78e-4)" "unprognostic (1.70e-1)" "unprognostic (2.84e-2)" "unprognostic (6.54e-2)" "unprognostic (4.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.67e-7)" "unprognostic (8.83e-2)" "unprognostic (2.24e-1)" "unprognostic (7.49e-2)" "unprognostic (7.04e-2)" 0.1 0.4 0.3 0.3 0.3 0.1 0.2 0.3 21.5 0.5 0.2 0.5 0.4 0.4 0.2 1.3 0.3 0.2 0.5 2.6 0.2 0.2 0.5 0.2 0.2 4.3 0.2 0.5 1.6 0.1 0.0 0.2 2.0 0.3 0.5 0.0 1.1 0.2 0.6 1.5 0.5 0.3 1.1 0.1 0.2 117.7 0.3 1.0 0.1 0.0 1.3 0.1 1.0 0.4 0.2 0.0 0.3 0.1 0.2 0.6 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.4 0.3 0.1 0.1 0.2 0.1 0.3 0.0 0.1 0.4 0.1 0.5 0.1 0.2 0.3 0.4 0.0 0.2 0.2 0.4 0.2 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.7 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.2 0.6 0.1 0.0 1.3 0.1 0.2 0.1 0.1 0.3 0.2 0.3 0.1 0.2 0.1 0.1 55.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 21.5 2.6 0.2 4.3 0.2 2.0 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.2 0.1 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.2 0.0 0.0 31.5 6.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 909.7 151.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "liver: 7525.8;retina: 2433.0" "Group enriched" "Detected in many" 9 "Hepatocytes: 7205.2;Muller glia cells: 12965.3" "Cancer enriched" "Detected in many" 42 "liver cancer: 783.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 48 "Hep G2: 780.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" NA NA 19800000000000 98000000000 "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "CAB009538: AB_793365, HPA001527: AB_1080357, HPA005692: AB_1080354" "prognostic favorable (4.05e-4)" "unprognostic (2.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.50e-1)" "unprognostic (8.99e-2)" "unprognostic (5.18e-2)" "unprognostic (6.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (2.35e-13)" "unprognostic (2.17e-3)" "unprognostic (5.49e-2)" "unprognostic (3.47e-3)" "unprognostic (9.70e-2)" 80.9 1.2 186.3 1.0 412.5 2.4 13.3 591.8 274.2 2.0 58.9 2.3 0.9 1.7 1.4 11.0 1.4 1.9 12.1 173.7 287.7 3.4 7525.8 1.9 1.3 786.9 385.4 2.1 4.6 2.2 4.4 1.3 628.2 5.4 1.2 2433.0 55.8 1.8 2.1 4.2 1.6 1.5 484.9 2.9 1.9 14.3 398.1 1.2 2.2 2.7 3.0 1.2 2.8 862.1 1.9 1.4 1.8 1.2 5.5 3.4 0.9 1.9 2.0 1.0 0.8 3.4 1.5 1.7 1.6 1.8 1.2 2.1 1.3 1.8 1.5 1.1 0.7 16.3 2.7 780.9 1.3 4.6 2.7 2.4 3.8 1.0 1.7 1.8 2.2 0.9 6.4 2.1 2.6 1.3 1.1 1.2 1.2 1.2 1.8 1.5 2.9 1.2 1.1 3.1 1.9 1.4 2.4 2.6 7.0 1.3 1.9 1.3 2.9 2.4 1.5 1.6 1.1 1.7 3.0 1.4 2.0 1.5 1.6 0.6 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 186.3 412.5 591.8 274.2 173.7 287.7 786.9 385.4 628.2 484.9 398.1 862.1 0.7 16.0 32.4 36.2 11.4 1.0 5.6 0.6 0.0 101.3 5.3 4.3 2.7 117.2 22.9 0.0 91.8 0.2 0.2 0.1 1.9 0.7 5.4 0.8 1.0 16.7 0.0 56.2 34.2 1.1 0.3 3.9 0.0 0.6 17.7 1.3 87.4 7205.2 0.1 47.1 34.7 0.0 0.0 124.7 0.3 3.8 0.3 4.7 0.0 9.4 0.6 12965.3 0.0 45.2 1077.2 1.1 0.0 0.4 0.0 18.7 0.0 0.5 22.1 400.4 0.0 11.6 0.4 0.5 0.4 3.6 0.0 0.3 7.8 0.5 0.0 3.0 TFF1 "BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2" ENSG00000160182 "Trefoil factor 1" P04155 21 42362282-42366535 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "stomach 1: 7973.0" "Group enriched" "Detected in many" 9 "Gastric mucus-secreting cells: 12908.9;Pancreatic endocrine cells: 14603.3" "Group enriched" "Detected in many" 10 "breast cancer: 402.1;colorectal cancer: 268.3;pancreatic cancer: 805.7;stomach cancer: 744.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "MCF7: 13512.4;OE19: 5337.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002170, HPA003425" Enhanced "Secreted to digestive system" NA NA 950000 "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002170: AB_563985, HPA003425: AB_1848260" "prognostic favorable (5.00e-4)" "unprognostic (8.81e-3)" "unprognostic (9.82e-2)" "prognostic favorable (5.67e-4)" "unprognostic (2.42e-1)" "unprognostic (1.72e-3)" "unprognostic (8.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" "unprognostic (6.62e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (7.72e-3)" "unprognostic (1.07e-1)" 2.3 0.3 0.0 20.3 0.0 0.0 26.7 0.0 0.0 9.7 0.0 114.7 34.8 0.2 0.0 18.3 0.9 167.2 0.6 0.0 0.0 0.9 0.8 1.3 0.2 0.0 0.0 0.2 10.7 0.0 0.2 1.1 0.0 25.0 108.4 0.0 32.4 0.7 0.2 0.1 68.4 4.8 0.0 3.1 7973.0 0.1 0.0 0.2 5.3 0.0 0.2 30.6 2.2 0.0 0.0 42.7 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 16.2 5.7 0.0 1.1 0.0 1.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 13512.4 4.6 0.5 5.5 5337.9 223.4 1.7 0.0 0.2 0.0 1.4 0.3 0.2 0.0 5.0 0.0 1.3 5.0 0.1 0.0 0.0 3.5 0.1 0.0 3.6 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 18.7 0.0 6.1 5.9 0.0 0.0 432.7 197.2 0.0 564.7 12.1 35.0 0.0 0.1 3.1 601.9 0.0 245.7 0.0 1.8 0.2 3.5 430.2 0.0 0.0 821.8 3.1 5.1 12908.9 2.9 13.4 0.0 0.0 1.6 0.2 0.0 0.0 1395.6 111.9 0.0 0.0 0.0 0.0 9.2 0.0 0.0 10.3 0.0 0.0 0.0 0.0 14603.3 500.9 0.0 40.6 432.4 78.0 0.0 2.8 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 8.9 0.0 80.0 232.6 TFF2 SML1 ENSG00000160181 "Trefoil factor 2" Q03403 21 42346357-42350997 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 6852.1" "Group enriched" "Detected in some" 5 "Cholangiocytes: 2057.4;Gastric mucus-secreting cells: 7217.7" "Group enriched" "Detected in many" 11 "pancreatic cancer: 320.9;stomach cancer: 244.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.4;Karpas-707: 20.0;OE19: 55.4;PC-3: 145.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025834, HPA036705" Enhanced "Secreted to digestive system" NA NA 890000 "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB025834: , HPA036705: AB_2675263" "unprognostic (3.95e-2)" "unprognostic (9.87e-2)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.89e-2)" "unprognostic (5.55e-2)" "unprognostic (1.27e-9)" "unprognostic (1.99e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (5.26e-3)" 1.4 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.8 0.0 6.5 1424.4 0.1 0.0 3.4 1.2 105.4 0.2 0.0 0.0 0.3 4.0 1.0 0.0 0.0 0.0 0.0 17.2 0.0 0.2 1.0 0.0 0.1 4.2 0.0 2.9 0.0 0.1 0.1 0.5 0.2 0.0 2.7 6852.1 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 35.4 0.0 0.2 0.0 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 2.9 0.0 2.6 55.4 145.2 1.1 0.0 8.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.1 0.0 0.0 2.7 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.0 0.0 0.0 0.0 3.6 0.5 0.2 2057.4 0.0 0.0 0.0 0.0 0.0 3.4 0.0 104.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 93.8 0.2 1.3 7217.7 0.0 0.0 0.5 0.0 6.1 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 2.9 5.4 0.0 0.6 0.0 0.0 0.0 0.0 833.8 5.5 0.0 11.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.0 0.0 0.1 11.8 TFF3 "HITF, ITF" ENSG00000160180 "Trefoil factor 3" Q07654 21 42311667-42315651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 305.8;intestine: 355.3;salivary gland: 340.2;thyroid gland: 416.7" "Cell type enriched" "Detected in many" 10 "Intestinal goblet cells: 33890.3" "Cancer enhanced" "Detected in all" "colorectal cancer: 765.0" "Region enriched" "Detected in single" 6 "midbrain: 1.9" "Immune cell enriched" "Detected in single" 9 "eosinophil: 1.8" "Lineage enriched" "Detected in single" 18 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "MCF7: 58.7;OE19: 126.6;T-47d: 27.8;TIME: 105.0" "CAB020681, HPA035464" Enhanced Approved Nucleoplasm,Nucleoli "Secreted to blood" No NA 151000000 6500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Nucleoli "CAB020681: , HPA035464: AB_2674636" "unprognostic (2.84e-2)" "unprognostic (3.61e-3)" "unprognostic (1.07e-1)" "prognostic favorable (5.60e-6)" "unprognostic (1.28e-1)" "unprognostic (2.35e-2)" "unprognostic (2.13e-1)" "unprognostic (5.03e-2)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (3.71e-1)" "unprognostic (6.90e-2)" "unprognostic (4.31e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" "unprognostic (3.86e-2)" 11.5 5.9 0.1 27.8 0.1 2.2 26.3 0.3 0.2 305.8 0.1 355.3 208.0 2.8 0.5 22.7 49.8 82.8 3.5 0.1 0.1 5.7 6.6 9.9 3.5 0.1 1.9 3.5 6.1 0.0 1.3 0.1 0.2 9.8 305.8 0.1 340.2 1.6 0.9 6.7 290.6 8.4 0.1 23.1 7.4 0.5 0.2 1.8 416.7 1.7 0.9 3.6 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 58.7 0.0 0.7 0.1 126.6 12.1 0.0 9.0 0.3 0.1 0.0 16.1 0.1 0.0 1.7 0.0 0.0 27.8 0.0 105.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 1.9 0.2 0.1 0.2 0.1 36.9 16.0 25.3 0.0 15.4 41.6 15.1 196.3 3.4 0.1 804.5 444.7 21.6 919.3 595.9 22.0 0.0 0.6 3.4 2188.7 0.0 9.4 0.5 29.3 1.4 322.8 770.9 0.0 0.0 67.8 0.7 21.5 71.4 11.4 59.2 2.0 170.3 5.8 2.1 5.0 0.0 33890.3 3263.2 3.4 42.4 9.0 2.5 2.8 96.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 1855.5 7.9 6.1 73.0 2788.7 0.1 453.2 0.1 0.0 1.1 28.2 1.0 0.3 4.3 38.6 0.8 14.9 0.6 1376.3 107.7 TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.3;placenta: 191.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2284.2;Hepatic stellate cells: 872.4;Syncytiotrophoblasts: 879.2" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.3;neutrophil: 1.3;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "HHSteC: 386.2;HUVEC TERT2: 742.5;LHCN-M2: 459.9;TIME: 451.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" NA NA 58100000 87000000 "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" 67.5 12.6 2.6 20.5 3.4 8.2 52.3 4.9 5.8 41.5 7.4 23.3 52.5 25.7 18.5 33.3 35.6 57.6 38.5 4.1 2.2 56.3 272.3 126.7 33.3 6.8 2.5 26.5 25.0 7.1 6.1 191.2 3.9 15.7 27.4 4.5 15.0 12.8 26.8 19.8 41.8 30.7 3.7 20.7 19.2 6.9 3.6 11.1 36.2 42.8 17.7 52.9 29.8 3.2 38.9 24.7 29.3 0.8 224.3 267.7 0.7 66.0 156.3 42.7 65.1 22.6 192.6 0.7 27.3 52.7 74.7 2.1 15.9 3.6 110.3 1.9 7.6 12.3 73.8 197.3 386.2 0.9 0.4 123.1 5.1 232.8 61.9 93.4 742.5 0.7 31.2 0.7 459.9 35.4 4.6 0.7 22.9 0.8 68.8 0.3 40.2 0.3 72.9 1.4 0.3 0.5 56.7 2.1 3.5 95.8 0.7 0.2 451.4 30.6 29.0 61.4 13.5 1.1 1.7 0.4 239.4 0.6 35.4 3.3 0.2 0.2 0.2 0.1 0.1 0.4 0.1 0.0 0.2 0.5 0.2 0.2 1.3 0.5 0.1 2.7 0.1 2.3 2.6 3.4 4.9 5.8 4.1 2.2 6.8 2.5 3.9 3.7 3.6 3.2 99.2 35.3 335.5 1.3 4.4 20.8 2.9 33.5 4.6 0.6 16.1 9.1 7.0 173.0 102.5 38.6 0.0 59.5 4.8 0.5 13.7 140.0 41.5 7.3 74.2 287.1 105.0 43.1 0.7 273.1 2284.2 283.0 12.2 5.3 13.9 1.5 872.4 382.1 50.2 1.7 0.2 11.3 158.7 63.7 41.3 15.2 171.8 21.9 26.6 13.1 33.7 33.1 1.0 0.0 0.1 157.6 34.1 70.0 9.5 8.0 36.6 109.4 45.2 1.1 216.9 141.2 127.8 2.7 0.5 10.2 18.5 879.2 8.1 30.6 18.5 16.7 TFPI2 "PP5, REF1, TFPI-2" ENSG00000105825 "Tissue factor pathway inhibitor 2" P48307 7 93885396-93890753 "Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "placenta: 954.6" "Cell type enhanced" "Detected in many" "Ductal cells: 1476.3;Glandular and luminal cells: 575.6;Prostatic glandular cells: 412.6;Syncytiotrophoblasts: 2184.1" "Cancer enhanced" "Detected in all" "renal cancer: 65.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 3001.0;hTEC/SVTERT24-B: 1373.4;U-138 MG: 1245.9;U-2197: 1050.8;U-87 MG: 2051.0" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 29.7" "CAB010142, HPA049158, HPA070525" Enhanced "Secreted to extracellular matrix" NA NA 51000 "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010142: AB_628166, HPA049158: AB_2680659, HPA070525: " "prognostic favorable (8.33e-7)" "unprognostic (2.20e-2)" "unprognostic (2.10e-2)" "prognostic favorable (5.42e-4)" "unprognostic (5.19e-3)" "unprognostic (3.98e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-2)" "unprognostic (6.86e-2)" "unprognostic (7.54e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (3.38e-3)" "unprognostic (3.65e-2)" "unprognostic (1.97e-1)" "unprognostic (7.91e-2)" 51.3 28.3 0.6 36.5 0.7 0.3 30.0 0.5 1.6 2.7 1.2 3.5 1.3 32.1 5.5 2.2 19.1 15.6 7.8 0.6 4.0 20.5 21.2 11.3 3.0 5.0 0.7 46.7 76.6 0.1 9.7 954.6 0.7 7.1 2.0 51.7 4.0 5.5 2.6 1.0 1.4 9.6 0.6 4.1 5.1 0.7 1.4 6.9 0.8 1.4 1.2 26.6 1.0 0.9 1.4 179.6 42.0 1.9 99.8 15.4 0.5 178.3 33.5 20.6 15.0 0.3 1.6 0.0 3001.0 47.0 43.9 18.6 1.1 216.1 24.6 2.8 1.3 0.1 10.2 0.7 545.7 0.0 0.9 9.1 10.7 1373.4 90.1 200.0 449.0 0.0 0.4 2.2 210.1 0.3 0.4 0.7 10.8 0.0 45.7 0.5 0.0 0.2 52.1 5.4 1.6 110.2 0.0 12.7 1.2 29.9 1.5 2.9 680.3 1245.9 13.2 1050.8 1.8 0.1 4.4 14.6 2051.0 0.3 140.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.7 0.5 1.6 0.6 4.0 5.0 0.7 0.7 0.6 1.4 0.9 141.3 3.2 3.9 0.0 1.2 0.6 311.3 77.9 0.6 17.5 37.2 7.9 0.5 21.5 122.9 318.2 39.6 16.1 0.6 0.0 0.0 1476.3 0.0 280.3 38.3 122.3 0.0 2.7 0.0 41.9 214.2 137.2 0.0 575.6 0.0 0.1 108.1 1.4 16.2 3.3 0.0 0.5 12.2 4.1 4.0 0.1 1.5 5.2 3.6 2.8 17.1 22.4 0.0 0.0 0.0 39.4 0.0 0.0 0.2 412.6 0.0 1.7 27.4 161.3 0.0 7.0 35.5 0.4 3.6 1.1 1.4 2184.1 4.9 0.7 0.0 35.0 TFRC "CD71, p90, TFR1" ENSG00000072274 "Transferrin receptor" P02786 3 196027183-196082096 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 254.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 556.4;Syncytiotrophoblasts: 502.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 860.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000153, HPA028598" Enhanced Supported Endosomes,Lysosomes "Secreted to blood" NA NA 1310000000 38000000 "Cluster 27: Non-specific - Gene expression" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Endosomes, Lysosomes" "CAB000153: AB_2533029, HPA028598: AB_10601599" "unprognostic (2.95e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" "unprognostic (6.75e-2)" "unprognostic (7.88e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.92e-2)" "unprognostic (3.30e-3)" "unprognostic (4.35e-2)" "unprognostic (1.34e-2)" "unprognostic (1.14e-2)" "unprognostic (3.63e-3)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (2.96e-4)" "unprognostic (2.62e-2)" 44.6 28.7 21.6 63.4 18.3 254.5 20.2 18.5 32.3 31.3 15.7 77.2 35.9 23.8 11.1 36.0 25.9 24.9 31.0 21.9 19.0 26.4 27.8 78.0 23.0 24.2 19.9 93.9 15.9 44.8 13.1 103.2 26.3 13.2 55.6 47.3 15.7 13.4 76.2 21.8 32.1 31.5 20.8 15.5 21.4 21.6 25.3 22.0 20.1 68.7 28.1 68.5 17.4 20.7 175.3 155.0 69.8 142.1 151.7 87.3 438.7 242.5 183.7 168.1 276.3 384.6 156.6 178.5 446.3 91.0 363.5 261.8 243.3 81.1 204.2 860.4 82.4 677.4 120.2 179.2 119.4 561.8 130.4 99.1 78.6 144.5 129.0 47.8 56.9 95.6 287.3 164.1 132.8 161.7 185.8 116.8 214.9 228.6 314.0 97.3 103.9 214.1 148.3 435.3 159.3 65.9 234.4 613.9 55.2 115.9 595.0 115.8 72.5 198.4 159.7 175.3 369.7 46.3 387.8 276.7 232.3 149.2 122.3 0.0 1.6 2.2 2.2 7.3 1.4 5.1 2.4 1.5 3.5 3.1 2.1 1.7 0.2 1.9 13.2 7.1 6.4 2.1 21.6 18.3 18.5 32.3 21.9 19.0 24.2 19.9 26.3 20.8 25.3 20.7 25.4 44.8 32.1 43.1 46.6 60.3 37.2 33.6 21.1 53.1 37.1 34.9 103.0 41.5 38.8 20.2 148.0 122.5 53.2 156.6 0.0 49.4 3.5 35.3 20.3 23.6 56.1 556.4 24.7 41.8 25.3 32.4 77.5 56.1 23.4 40.2 8.6 93.2 73.4 13.5 28.3 67.8 22.4 37.1 77.6 5.3 11.5 161.7 17.8 44.0 49.4 22.0 9.2 11.6 8.2 52.0 50.8 8.6 42.1 25.6 48.3 13.1 32.1 44.4 26.3 36.3 29.3 23.8 18.2 51.3 35.8 502.7 42.6 16.6 103.5 23.7 TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 9329.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 5.5;Cardiomyocytes: 3.0;Early spermatids: 2.3;Late spermatids: 2.2;Microglial cells: 1.9;Proximal tubular cells: 4.0" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;HSkMC: 2.4;Karpas-707: 5.6;PC-3: 2.8;U-266/70: 2.0;U-266/84: 1.8" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in some" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" 1.6 3.2 3.0 0.5 0.4 7.8 1.4 0.2 1.9 1.2 1.5 1.8 0.0 1.8 1.0 2.0 0.4 8.6 13.6 1.7 0.2 2.9 3.6 4.2 12.0 0.4 0.5 1.2 8.0 2.7 1.2 0.2 0.5 3.6 0.1 0.1 3.9 1.8 2.8 6.3 1.7 0.1 0.2 1.9 2.2 2.9 0.5 0.4 9329.0 0.0 0.6 0.6 1.7 0.5 0.0 0.0 0.0 0.0 0.5 0.7 0.3 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.4 1.7 0.6 0.0 0.5 0.0 0.7 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 2.0 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.1 0.1 3.0 0.4 0.2 1.9 1.7 0.2 0.4 0.5 0.5 0.2 0.5 0.5 0.3 0.0 0.6 0.3 0.2 0.0 5.5 0.1 0.0 0.0 0.1 0.1 3.0 0.0 1.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.3 0.3 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.4 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.5 0.1 0.1 0.0 0.4 0.1 0.5 0.0 4.0 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.0 0.6 0.0 0.2 1.1 0.0 1.2 TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 59.3;Pancreatic endocrine cells: 74.5;Urothelial cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.3;eosinophil: 23.8;neutrophil: 23.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 23.8" "Cell line enhanced" "Detected in many" "A-431: 72.5;CAPAN-2: 82.5;HBEC3-KT: 72.3;OE19: 54.6;RPTEC TERT1: 72.6;U-87 MG: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" No No 57900 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" 2.2 0.5 9.2 5.0 16.8 1.6 6.9 15.0 12.2 6.1 5.2 10.7 8.5 1.3 2.9 25.5 6.1 14.1 0.7 10.4 11.7 13.4 4.5 3.9 4.1 21.0 15.8 0.1 7.5 3.0 0.5 1.9 18.5 2.4 7.9 7.4 6.4 1.2 0.1 12.2 10.0 1.4 16.6 5.8 8.5 2.5 13.2 1.0 8.1 0.3 9.0 10.0 12.8 27.3 72.5 11.3 0.1 0.2 0.0 0.0 0.0 11.0 0.0 0.3 0.1 0.2 82.5 0.0 43.2 0.4 11.2 37.1 0.6 72.3 0.1 0.1 1.6 0.0 1.8 6.0 0.0 0.9 0.1 0.0 29.1 0.1 27.8 3.4 0.0 5.6 0.0 0.4 0.0 2.6 0.1 1.4 1.1 54.6 22.9 0.0 0.5 19.8 72.6 27.2 0.6 0.1 5.8 0.0 0.1 0.2 9.8 0.7 0.6 0.3 4.9 0.1 15.7 0.4 0.6 0.1 69.0 2.4 25.6 11.3 0.8 23.8 1.7 0.2 4.4 0.0 1.0 1.0 1.0 0.0 0.5 0.4 23.8 0.3 0.0 0.0 0.0 0.7 9.2 16.8 15.0 12.2 10.4 11.7 21.0 15.8 18.5 16.6 13.2 27.3 0.4 6.4 2.7 0.3 0.2 16.2 12.3 16.9 10.8 1.4 9.8 12.1 2.3 24.3 21.8 25.8 0.0 0.0 2.2 19.8 1.9 37.3 21.3 8.1 0.7 1.7 1.2 0.0 0.8 10.0 0.0 0.6 13.7 10.5 5.7 0.0 0.0 3.0 3.9 0.0 3.6 6.2 12.2 3.2 2.4 1.9 0.3 4.1 0.0 6.5 18.2 7.9 2.1 59.3 36.1 74.5 9.0 0.0 0.7 16.8 21.1 6.6 20.4 0.7 0.0 0.1 1.1 0.6 0.2 12.2 24.9 0.0 1.9 0.0 5.6 63.6 TGFB1 "CED, DPD1, TGFB, TGFbeta" ENSG00000105329 "Transforming growth factor beta 1" 19 41301587-41353922 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 438.3;Extravillous trophoblasts: 452.1;Macrophages: 188.8;NK-cells: 223.5;T-cells: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000361, HPA073356" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 1290000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" Cytosol "CAB000361: AB_2201910, HPA073356: " "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (3.29e-2)" "unprognostic (4.90e-2)" "unprognostic (3.75e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (8.51e-3)" "unprognostic (5.63e-3)" "unprognostic (2.47e-2)" "unprognostic (5.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.65e-3)" "unprognostic (2.79e-2)" "unprognostic (6.39e-2)" "unprognostic (4.86e-3)" 39.8 28.6 10.8 39.7 10.7 82.9 25.4 11.8 9.4 53.2 9.5 31.0 14.4 45.9 7.4 52.2 27.7 18.1 35.8 9.5 15.5 35.8 14.7 63.4 34.0 24.5 14.9 17.4 14.3 11.5 18.0 32.1 17.6 31.6 8.4 0.6 21.2 19.8 8.1 29.3 37.8 21.8 18.4 88.9 20.1 8.1 19.4 16.7 20.2 8.3 25.7 44.1 45.3 17.7 57.7 87.6 3.4 0.3 41.7 35.3 10.0 81.9 64.4 25.2 15.4 40.4 30.1 57.0 88.6 110.5 26.8 30.1 17.8 54.6 11.1 76.6 17.9 199.0 18.0 50.4 47.7 54.9 119.6 45.0 17.5 50.5 32.7 138.7 135.2 21.1 108.0 116.8 27.9 42.1 43.1 79.6 9.4 12.0 52.7 44.4 13.1 85.4 46.8 20.3 0.3 6.5 23.9 0.1 15.1 32.5 1.9 36.3 170.3 96.4 77.2 20.7 91.2 74.4 31.7 36.3 90.3 106.4 16.4 1.1 0.8 3.9 0.7 1.2 0.6 0.2 0.3 0.4 0.5 0.3 0.2 0.3 2.4 0.3 0.8 0.9 0.3 0.9 10.8 10.7 11.8 9.4 9.5 15.5 24.5 14.9 17.6 18.4 19.4 17.7 55.0 0.0 0.0 3.3 120.6 44.4 36.5 64.8 38.7 0.2 14.4 9.7 2.3 4.3 17.2 16.5 0.0 5.4 438.3 1.4 0.0 12.8 1.0 5.7 18.2 63.1 0.0 28.0 1.6 17.1 452.1 34.3 14.3 5.0 64.9 20.0 71.4 2.7 141.2 0.0 2.1 1.4 22.4 136.1 158.6 1.8 12.2 188.8 23.2 30.0 105.8 0.3 223.5 0.0 0.6 45.1 16.4 18.0 156.5 32.9 0.4 9.0 9.7 0.7 39.5 13.9 78.6 3.1 8.0 40.3 18.9 55.7 221.9 4.1 0.8 31.1 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 TGFBI "BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1" ENSG00000120708 "Transforming growth factor beta induced" Q15582 5 136028988-136063818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Sensory transduction, Vision" "Amyloidosis, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 457.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.8;Kupffer cells: 292.9;Langerhans cells: 251.2;Macrophages: 198.9;Pancreatic endocrine cells: 590.1;Smooth muscle cells: 326.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 77.3" "Group enriched" "Detected in many" 32 "classical monocyte: 252.3;intermediate monocyte: 149.1;myeloid DC: 156.9;non-classical monocyte: 121.4;plasmacytoid DC: 324.5" "Group enriched" "Detected in all" 46 "dendritic cells: 324.5;monocytes: 252.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2857.3;GAMG: 2417.8;HSkMC: 2675.6;hTCEpi: 1915.6;LHCN-M2: 2269.4;U-2197: 1916.3;U-87 MG: 3667.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA008612, HPA017019" Enhanced "Secreted to blood" NA NA 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA008612: AB_1857970, HPA017019: AB_2669511" "unprognostic (1.05e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.38e-3)" "prognostic favorable (1.17e-4)" "unprognostic (5.21e-3)" "unprognostic (5.53e-3)" "unprognostic (4.60e-2)" "unprognostic (8.71e-3)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.42e-3)" "unprognostic (2.26e-1)" "prognostic unfavorable (7.82e-10)" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (3.42e-1)" "unprognostic (1.70e-3)" 133.2 55.3 9.5 164.0 10.4 25.9 112.2 10.0 25.5 51.8 51.9 92.8 48.2 59.7 41.6 28.7 59.7 146.1 95.5 10.4 11.5 124.0 132.1 89.7 66.2 15.8 11.9 25.4 22.4 18.4 77.6 457.6 15.7 69.5 84.4 2.8 68.3 58.9 34.8 314.1 65.3 291.0 12.2 121.1 67.4 7.6 77.3 57.7 40.4 41.7 44.4 138.9 39.0 14.0 102.2 405.6 0.8 3.8 1104.3 354.4 1.5 295.1 42.9 209.9 125.1 186.4 1276.3 0.1 181.6 2857.3 2417.8 498.0 1.0 981.4 208.0 2.3 0.1 0.1 451.6 501.3 718.9 0.7 3.9 2675.6 1915.6 77.9 93.1 827.5 188.1 0.2 0.2 3.8 2269.4 4.8 0.7 0.7 13.1 5.1 0.9 0.4 24.3 3.4 96.7 8.8 1.3 0.7 473.7 15.5 3.9 452.8 3.7 110.9 745.6 1419.3 59.8 1916.3 1139.6 0.3 0.7 1.9 3667.3 0.9 1077.5 1.6 252.3 1.0 0.9 149.1 1.0 1.0 1.0 2.0 156.9 0.4 0.3 1.0 5.3 6.2 121.4 324.5 0.5 108.5 9.5 10.4 10.0 25.5 10.4 11.5 15.8 11.9 15.7 12.2 77.3 14.0 12.4 3.2 21.4 0.0 6.3 119.4 4.8 141.8 4.6 0.4 1.9 5.5 8.9 4.3 21.8 1.8 0.0 9.9 146.5 1.3 0.0 67.5 2.4 2.3 57.9 16.4 3.5 8.8 0.4 112.6 8.5 113.5 0.5 1.7 5.1 0.0 21.0 25.7 251.8 1.7 0.0 7.8 6.1 292.9 251.2 1.9 10.2 198.9 49.8 4.7 151.1 0.3 6.2 0.0 0.0 590.1 0.0 2.2 1.9 1.0 0.1 2.7 8.5 0.2 26.3 156.8 326.1 0.2 0.9 1.9 55.7 19.4 8.5 10.8 0.9 2.5 TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.9;Hepatic stellate cells: 322.7;Leydig cells: 146.3;Skeletal myocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 35.2" "Group enriched" "Detected in many" 18 "NK-cells: 16.6;T-cells: 35.2" "Cell line enhanced" "Detected in many" "ASC diff: 227.2;ASC TERT1: 108.4;RT4: 57.1;U-2197: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" NA NA 50000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB018971: , HPA008257: AB_1080258" "unprognostic (7.57e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (9.39e-3)" "prognostic favorable (4.84e-4)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "prognostic favorable (4.99e-4)" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.08e-2)" 66.3 35.2 6.9 9.2 6.8 5.0 62.1 7.6 8.0 56.6 20.4 28.8 8.2 33.9 24.2 28.5 36.6 20.0 16.2 7.6 6.7 28.2 16.6 27.3 7.2 6.0 10.1 81.5 12.3 5.9 7.1 58.5 7.8 16.4 12.5 1.5 35.0 32.7 12.8 25.0 19.7 27.4 7.9 40.0 18.1 11.0 8.0 7.7 13.2 29.4 4.2 47.3 28.6 7.8 9.9 9.4 14.1 2.4 227.2 108.4 44.6 7.1 35.3 8.1 9.9 4.4 1.4 0.1 1.7 13.0 6.4 1.4 3.6 1.0 6.2 34.1 7.6 0.0 11.1 41.2 5.0 0.3 0.1 26.3 4.7 17.8 4.0 1.3 4.2 0.0 23.6 0.7 2.4 0.2 0.1 0.1 5.9 4.6 3.2 0.5 4.8 2.1 3.2 57.1 0.7 0.0 3.4 0.2 20.4 5.8 1.2 3.7 12.7 13.5 3.5 78.0 1.7 34.8 3.3 0.0 2.8 1.9 1.7 1.2 0.0 0.0 35.2 0.2 19.4 0.0 8.7 19.2 0.0 0.0 2.7 12.7 0.6 16.6 1.4 1.2 4.5 8.1 6.9 6.8 7.6 8.0 7.6 6.7 6.0 10.1 7.8 7.9 8.0 7.8 77.6 9.6 9.7 58.8 3.1 37.6 10.0 2.3 44.3 0.3 38.2 60.1 20.7 30.0 4.2 31.3 2.1 27.5 66.7 0.5 3.9 2.0 54.3 11.2 32.8 90.5 24.0 10.7 7.7 5.1 12.0 143.9 5.1 8.1 2.5 20.5 322.7 21.0 11.8 0.0 34.0 1.9 8.2 23.2 29.4 29.8 146.3 5.2 35.6 82.4 0.7 1.2 62.8 7.5 0.9 3.3 0.4 74.4 21.3 8.5 1.4 20.9 8.3 0.2 13.1 187.2 36.5 0.8 2.2 17.2 34.1 58.0 36.9 92.2 3.7 8.0 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 432.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.5;Cytotrophoblasts: 311.1;Ductal cells: 226.7;Endometrial stromal cells: 459.1;Hepatic stellate cells: 408.0;Hepatocytes: 205.7;Pancreatic endocrine cells: 326.5;Syncytiotrophoblasts: 374.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 1546.7;EFO-21: 505.5;hTERT-RPE1: 994.3;HUVEC TERT2: 695.3;TIME: 924.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Yes No 1700000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 105.9 45.1 23.0 68.4 22.3 3.2 30.3 22.9 29.5 432.0 53.0 30.6 29.8 266.3 28.3 37.3 217.7 127.7 394.9 21.4 23.0 76.7 244.1 288.5 18.0 25.4 22.5 40.6 25.6 19.3 95.9 234.3 26.0 88.7 20.8 2.1 9.8 56.6 63.9 4.0 63.7 159.0 24.4 32.7 62.3 3.9 30.6 15.4 36.3 33.4 10.3 154.2 87.8 24.8 65.0 47.5 0.2 1.8 47.3 5.1 24.0 95.5 45.2 0.7 1.8 78.4 1546.7 0.1 505.5 1.0 105.4 1.7 0.1 221.7 3.4 0.7 0.2 10.3 2.6 35.0 191.9 0.0 0.5 5.2 0.4 40.2 0.3 994.3 695.3 0.0 21.4 0.1 16.0 0.3 0.0 0.6 0.8 0.9 4.6 0.0 0.1 0.3 69.0 0.0 0.0 1.3 224.4 0.2 7.6 31.6 2.2 0.6 924.2 1.6 57.6 7.8 46.3 0.0 0.6 0.8 60.7 0.1 18.4 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 22.3 22.9 29.5 21.4 23.0 25.4 22.5 26.0 24.4 30.6 24.8 58.0 9.6 18.3 0.0 7.4 0.5 10.4 41.0 0.6 0.0 8.5 8.8 204.5 31.5 55.3 14.7 2.1 311.1 0.1 11.7 3.9 226.7 3.2 16.7 459.1 183.8 0.0 74.5 0.1 145.7 38.6 37.7 0.5 13.1 2.5 2.8 408.0 205.7 54.4 0.0 0.1 1.8 6.1 23.7 2.1 5.0 1.2 35.5 0.0 28.1 6.5 0.4 0.0 0.0 0.3 326.5 1.1 6.0 0.0 68.6 63.0 27.6 23.6 0.5 0.0 5.2 49.1 0.4 4.0 0.9 0.0 374.2 3.9 2.1 3.3 26.4 THBS1 "THBS, THBS-1, TSP, TSP-1, TSP1" ENSG00000137801 "Thrombospondin 1" P07996 15 39581079-39599466 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, Unfolded protein response" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 279.5;Granulosa cells: 228.3;Macrophages: 598.0;Smooth muscle cells: 283.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 15.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2610.2;HUVEC TERT2: 2494.4;LHCN-M2: 1863.4;TIME: 3552.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.6" "CAB033678, HPA059756" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 16000000000 1400000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB033678: AB_793044, HPA059756: AB_2684121" "unprognostic (1.72e-2)" "unprognostic (9.55e-3)" "unprognostic (7.49e-2)" "unprognostic (3.31e-1)" "unprognostic (4.34e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (6.40e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (8.47e-5)" "prognostic unfavorable (8.50e-4)" "unprognostic (1.00e-1)" "unprognostic (9.25e-3)" "unprognostic (1.48e-3)" 364.3 72.5 1.7 394.0 3.7 114.7 95.1 2.1 11.3 66.7 27.3 166.4 24.8 161.3 3.5 49.1 142.6 275.2 98.3 2.2 2.1 70.9 129.4 309.2 32.3 10.8 4.4 76.3 69.1 7.0 26.8 99.0 10.8 89.8 85.6 0.4 137.3 12.0 16.2 35.4 83.5 243.6 0.9 79.8 150.5 2.2 14.3 12.0 34.0 4.3 7.1 396.3 36.2 2.1 171.9 62.7 49.0 17.8 199.4 233.9 0.7 1025.7 861.6 283.6 185.5 185.0 135.7 1.0 348.4 2610.2 54.4 621.0 2.2 516.1 145.0 43.4 0.5 46.6 35.0 46.9 44.4 0.3 13.2 524.9 37.2 237.2 535.1 1123.6 2494.4 1.6 1.5 1.7 1863.4 14.7 0.8 3.6 8.9 17.7 20.3 0.7 125.7 1.3 430.6 472.6 0.6 0.4 300.7 16.4 18.5 60.8 178.6 3.3 3552.9 972.6 221.0 1141.1 1146.6 2.4 1.8 2.0 33.0 0.8 1064.4 0.3 8.7 15.7 0.7 0.8 2.7 0.0 0.4 0.5 0.5 0.1 0.1 0.1 1.5 7.8 0.1 0.4 0.0 10.5 1.7 3.7 2.1 11.3 2.2 2.1 10.8 4.4 10.8 0.9 14.3 2.1 19.0 25.6 19.6 0.7 4.9 95.7 131.2 37.6 181.6 0.1 66.8 69.8 48.7 18.6 19.9 69.9 6.2 1.9 8.2 144.5 0.0 52.1 0.2 64.9 127.7 79.2 3.6 0.0 0.9 127.5 2.5 279.5 15.8 38.2 162.7 228.3 44.6 7.4 6.3 0.0 1.3 46.4 48.8 105.9 97.9 0.3 1.8 598.0 39.2 13.1 5.9 0.1 3.1 0.0 0.1 183.9 55.1 0.4 5.9 79.2 8.5 48.3 11.9 1.5 6.6 59.0 283.8 0.2 0.3 51.8 51.0 2.1 19.5 10.8 67.8 42.1 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 THBS3 ENSG00000169231 "Thrombospondin 3" P49746 1 155195588-155209051 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 29 "Early spermatids: 297.1;Late spermatids: 1075.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 76.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA006293, HPA073242" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 9400000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA006293: AB_10602898, HPA073242: AB_2732223" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (2.43e-4)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.63e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (4.23e-1)" "unprognostic (4.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.88e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.38e-12)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (8.50e-3)" "unprognostic (2.26e-1)" 16.7 9.3 4.5 8.9 5.1 9.1 16.3 3.0 5.3 24.9 7.9 25.0 5.4 33.6 21.0 14.1 24.4 16.7 23.2 4.9 5.4 16.4 14.5 15.6 5.7 4.8 6.7 24.9 19.1 10.8 15.9 8.8 4.5 20.0 10.7 4.7 13.3 15.5 5.8 18.8 14.1 28.6 3.3 11.0 14.5 14.9 6.4 4.4 23.6 8.0 6.2 18.8 19.4 4.2 3.3 7.8 28.3 28.9 15.1 17.5 1.7 13.3 19.6 6.1 10.9 1.0 24.0 2.2 14.7 29.4 1.8 7.9 0.8 5.0 4.5 5.3 1.9 1.9 9.8 1.1 16.3 1.6 3.9 30.3 17.2 8.9 12.2 76.2 11.0 4.9 1.7 4.6 5.5 12.0 1.3 3.0 6.5 6.9 3.9 26.2 1.2 5.3 12.7 8.2 41.7 23.8 3.4 6.5 6.8 40.7 19.1 4.1 8.5 20.1 4.6 3.8 4.7 11.1 1.4 0.5 18.2 1.7 1.7 0.0 1.6 0.6 0.6 0.8 0.4 0.5 0.9 0.7 1.3 0.2 1.0 0.3 0.7 0.3 0.2 0.2 1.7 0.8 4.5 5.1 3.0 5.3 4.9 5.4 4.8 6.7 4.5 3.3 6.4 4.2 4.0 0.0 14.3 7.2 1.4 7.9 2.6 3.1 4.6 2.5 6.6 6.1 1.7 5.7 2.8 0.0 0.0 1.7 3.5 3.3 1.9 4.9 297.1 5.3 10.3 5.6 4.8 0.8 11.2 2.5 1.8 22.6 5.6 5.0 0.0 7.5 2.9 5.4 9.9 8.4 6.3 4.3 6.1 3.8 8.6 1075.2 23.3 3.7 10.6 0.0 1.9 1.5 1.0 0.0 3.2 3.7 2.9 10.1 1.4 2.3 2.7 3.8 2.6 3.7 0.0 11.8 8.1 20.8 4.8 3.7 5.3 1.4 2.2 2.4 3.4 2.2 THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 216.7;heart muscle: 167.9;smooth muscle: 251.4;tongue: 214.6" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 493.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.5" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.5" "Cell line enhanced" "Detected in some" "AF22: 3.1;THP-1: 7.0;U-2 OS: 2.8;U-266/70: 2.6" "Region enriched" "Detected in many" 8 "white matter: 85.7" "Region enriched" "Detected in many" 27 "spinal cord: 89.3" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 510000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB004597: AB_628352, HPA042426: AB_2677992" "unprognostic (1.41e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.64e-2)" "unprognostic (9.94e-2)" "unprognostic (8.10e-2)" "unprognostic (5.64e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-3)" "unprognostic (2.74e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.33e-4)" 216.7 1.2 15.4 5.2 19.6 10.6 26.8 13.8 13.0 2.1 5.0 58.1 2.2 26.8 1.6 6.0 2.5 10.4 167.9 12.2 24.5 0.7 0.3 1.3 1.1 22.3 25.3 4.1 22.8 35.7 14.3 0.2 19.9 9.0 8.7 7.5 46.5 5.7 77.2 2.9 3.3 251.4 21.7 0.3 8.6 8.7 28.0 3.6 27.0 214.6 4.0 3.5 5.8 20.0 0.1 0.0 3.1 0.2 0.2 1.3 0.3 0.1 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.2 0.8 0.1 0.1 0.4 0.8 0.1 0.4 0.3 0.0 0.2 1.7 0.0 0.0 0.9 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 2.4 0.0 0.0 0.0 0.9 0.0 0.2 0.0 2.5 0.7 0.0 0.0 0.2 1.3 0.0 7.0 0.0 0.0 2.8 0.2 0.2 2.6 0.1 0.4 1.1 2.2 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 19.6 13.8 13.0 12.2 24.5 22.3 25.3 19.9 21.7 28.0 20.0 57.0 0.0 1.1 37.2 0.7 0.3 0.1 0.2 2.2 1.3 0.8 1.8 9.1 0.0 0.7 3.7 56.3 0.1 0.5 0.0 0.0 0.2 40.8 0.3 0.8 9.4 9.0 0.0 9.7 0.0 0.0 84.2 0.5 0.3 0.0 5.9 0.4 0.2 0.1 1.7 12.7 0.0 0.0 0.0 0.3 7.2 0.9 2.7 1.8 6.5 0.0 2.2 0.0 60.3 24.0 0.0 0.0 43.6 0.3 1.0 0.0 0.8 0.2 1.9 493.0 78.9 116.9 14.5 2.1 0.6 1.0 0.0 2.1 1.2 0.0 0.0 THEM6 "C8orf55, DSCD75" ENSG00000130193 "Thioesterase superfamily member 6" Q8WUY1 8 142727223-142736927 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 82.4;RT4: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023255 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted - unknown location" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "HPA023255: AB_1845782" "unprognostic (6.20e-3)" "unprognostic (2.21e-1)" "unprognostic (9.10e-2)" "unprognostic (5.33e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-2)" "unprognostic (1.74e-2)" "unprognostic (6.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.44e-1)" "unprognostic (4.91e-2)" "unprognostic (6.76e-2)" "prognostic favorable (6.66e-7)" "unprognostic (7.02e-3)" "unprognostic (3.55e-2)" "unprognostic (2.39e-2)" "prognostic favorable (4.49e-4)" 14.3 17.2 15.8 4.4 13.9 5.3 15.6 14.4 18.3 9.6 12.0 13.3 11.5 6.9 3.5 21.0 9.4 7.3 16.6 16.1 15.4 21.6 47.0 10.6 6.5 20.7 17.2 4.4 23.1 15.7 12.5 8.3 16.7 12.5 5.1 1.4 16.3 10.3 12.4 16.6 11.6 3.5 15.0 11.0 15.6 3.7 15.9 6.8 14.2 7.2 4.1 17.2 11.5 14.2 28.5 23.1 3.5 23.9 10.9 3.8 16.6 14.3 11.8 21.5 14.9 14.2 41.5 11.9 31.8 5.4 8.0 64.4 10.2 31.0 3.5 9.9 28.2 9.1 12.3 28.9 11.9 5.3 9.2 5.5 10.9 4.2 6.0 4.3 18.4 16.6 4.3 5.9 3.7 82.4 21.7 1.3 5.4 53.0 74.5 24.9 2.4 27.4 25.9 114.0 53.1 20.8 21.9 64.7 18.6 3.2 31.9 4.3 10.7 9.2 6.7 26.8 2.5 3.8 5.6 5.2 9.5 25.7 11.6 7.2 4.9 2.6 10.9 9.2 16.6 5.1 11.6 14.1 4.7 6.7 13.6 12.9 0.7 11.1 9.0 3.6 11.6 9.1 15.8 13.9 14.4 18.3 16.1 15.4 20.7 17.2 16.7 15.0 15.9 14.2 35.4 9.6 5.8 6.2 6.7 3.6 7.5 5.7 2.8 10.4 24.7 25.3 7.4 11.5 7.8 18.4 6.2 18.3 11.5 16.6 5.9 13.7 3.3 5.5 3.0 14.6 31.8 11.6 11.3 11.6 10.1 4.8 7.7 9.0 0.0 6.6 19.2 20.8 11.4 16.8 7.8 13.5 6.1 3.1 1.4 15.7 2.8 3.9 5.4 2.8 2.3 13.5 16.5 11.6 7.3 9.4 9.0 4.1 3.7 10.7 29.0 16.2 2.4 11.3 0.0 6.1 4.3 2.7 5.7 18.4 7.7 3.4 10.3 8.2 22.4 25.1 THNSL2 "FLJ10916, SOFAT, TSH2" ENSG00000144115 "Threonine synthase like 2" Q86YJ6 2 88170295-88186636 "Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Proximal tubular cells: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 31.6;MCF7: 12.2;SK-MEL-30: 12.6;SuSa: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035395 Approved "Secreted - unknown location" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035395: AB_10601600" "unprognostic (1.51e-2)" "unprognostic (1.03e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (4.53e-2)" "unprognostic (8.73e-2)" "unprognostic (6.64e-2)" "unprognostic (7.26e-2)" "unprognostic (1.93e-1)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-2)" "unprognostic (2.01e-3)" "unprognostic (6.98e-2)" "unprognostic (8.81e-2)" "unprognostic (1.40e-1)" "unprognostic (1.24e-2)" 13.9 22.6 14.9 2.4 16.9 0.9 16.4 15.1 15.6 14.8 15.0 18.0 5.6 11.2 22.6 6.5 19.2 7.7 17.8 13.8 18.1 28.5 50.0 7.2 1.9 16.7 16.2 14.9 14.2 32.3 29.1 8.6 16.0 22.3 3.7 7.3 12.9 13.5 50.1 9.3 12.6 6.3 16.1 7.5 13.5 13.0 16.7 1.1 21.9 35.8 1.8 12.5 9.9 16.3 0.3 0.0 0.0 0.0 2.7 0.9 1.5 4.6 5.0 6.4 8.3 6.6 7.7 0.0 2.2 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.0 0.0 0.0 31.6 0.0 0.6 5.1 10.3 1.9 0.0 0.5 0.0 0.0 0.0 0.0 4.7 12.2 0.0 0.1 6.2 7.1 0.6 0.0 0.0 0.0 5.2 0.5 0.3 0.0 5.4 0.4 12.6 15.0 8.8 2.0 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.2 0.3 0.3 0.4 0.2 0.4 0.1 0.2 0.4 0.7 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 14.9 16.9 15.1 15.6 13.8 18.1 16.7 16.2 16.0 16.1 16.7 16.3 2.8 3.2 9.3 13.1 3.1 6.6 8.6 8.3 9.6 12.8 23.2 20.2 17.3 20.0 2.9 14.7 0.0 42.5 0.4 9.2 58.7 14.8 1.3 14.5 8.9 3.6 2.4 6.1 2.8 3.0 15.7 13.8 6.6 8.4 0.0 8.1 7.9 43.6 4.6 13.5 3.0 6.8 4.1 10.7 4.6 4.2 9.0 2.8 14.2 5.6 11.3 43.5 3.1 4.0 16.7 5.4 8.9 9.8 1.7 6.3 13.4 87.2 5.2 7.3 0.0 8.9 6.4 3.7 11.4 3.7 5.1 23.9 1.7 13.8 6.2 5.6 THPO "MGDF, MPLLG, TPO" ENSG00000090534 Thrombopoietin P40225 3 184371935-184381968 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 35.4" "Cell type enhanced" "Detected in some" "Early spermatids: 2.3;Hepatocytes: 12.7;Late spermatids: 4.0;Proximal tubular cells: 9.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.0;Hep G2: 15.6;K-562: 2.8;RPMI-8226: 4.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1070000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (5.57e-2)" "unprognostic (3.15e-2)" "unprognostic (1.75e-1)" "unprognostic (2.21e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (1.40e-3)" "unprognostic (4.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.25e-2)" 1.8 2.5 5.2 0.5 3.9 0.0 1.4 4.7 4.8 3.9 2.4 0.7 0.2 3.8 1.3 0.4 2.0 0.4 1.2 4.5 2.8 4.5 35.4 0.8 0.2 3.3 2.9 2.8 1.7 0.1 0.7 0.5 3.0 1.3 0.3 0.0 0.5 0.5 1.9 0.6 0.7 1.5 3.0 1.3 0.9 3.9 2.8 0.0 0.8 0.9 0.1 0.9 1.9 3.6 0.0 0.0 0.0 0.0 0.5 0.0 2.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 15.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.3 0.6 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 3.9 4.7 4.8 4.5 2.8 3.3 2.9 3.0 3.0 2.8 3.6 0.1 0.0 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 1.6 0.1 0.0 0.0 2.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 12.7 0.6 0.0 1.3 0.0 0.0 0.8 0.0 4.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 1.1 0.8 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 103.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 106.4;Basal squamous epithelial cells: 449.0;Microglial cells: 247.3;Squamous epithelial cells: 141.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 45.3;BJ hTERT+: 53.0;T-47d: 43.3;TIME: 66.6;U-2197: 44.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.0" "Secreted - unknown location" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" 4.8 8.4 9.8 1.6 7.8 0.0 14.7 6.1 8.6 103.7 9.5 7.0 7.9 22.2 7.8 60.3 37.0 10.9 41.6 8.5 7.2 14.2 7.0 10.3 0.9 7.8 9.1 3.1 6.4 0.7 9.7 3.6 7.6 34.0 6.9 1.2 11.4 15.0 3.0 8.5 8.7 10.3 7.0 1.9 12.0 3.1 15.9 1.6 8.8 2.5 2.5 13.3 38.5 5.9 6.0 45.3 0.8 13.0 6.7 40.2 0.2 22.0 53.0 11.2 5.8 0.3 8.7 0.0 17.7 7.8 38.5 17.0 1.8 9.1 6.8 2.0 2.0 0.0 4.4 0.0 4.3 0.0 0.0 3.0 6.7 6.7 26.6 30.5 20.7 0.0 0.0 0.5 9.2 9.1 0.0 0.1 3.9 0.1 7.8 0.0 0.7 0.8 29.5 6.0 0.7 5.5 8.8 10.9 0.0 5.0 43.3 0.1 66.6 0.2 1.0 44.4 11.8 0.0 0.3 0.0 10.4 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 7.8 6.1 8.6 8.5 7.2 7.8 9.1 7.6 7.0 15.9 5.9 1.1 19.2 9.0 6.5 0.0 13.9 106.4 11.3 449.0 3.0 48.7 43.9 60.1 58.6 7.5 5.5 6.2 0.4 0.8 16.2 1.9 18.3 7.5 19.3 13.2 9.8 3.0 0.0 17.1 1.8 0.4 12.5 2.6 31.8 0.0 0.3 6.1 12.3 0.2 0.0 19.1 6.1 0.0 0.0 2.1 16.9 17.4 1.6 8.8 247.3 0.0 0.3 0.0 8.5 6.7 13.6 11.0 74.4 1.2 94.6 29.3 0.5 11.0 0.9 0.0 16.8 6.6 0.9 1.7 141.5 10.9 0.8 3.1 42.2 13.2 29.7 THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Bipolar cells: 183.8;Horizontal cells: 208.6;Inhibitory neurons: 494.3;Oligodendrocyte precursor cells: 262.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cell line enhanced" "Detected in some" "A549: 10.3;HUVEC TERT2: 6.7;REH: 7.1;SH-SY5Y: 10.2;THP-1: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" 2.4 0.7 2.9 0.7 2.3 0.0 2.1 3.2 4.4 3.3 0.0 1.0 0.3 2.8 0.8 0.5 2.1 2.6 0.7 4.2 3.5 7.5 0.6 1.1 0.3 2.8 4.9 2.5 0.4 1.2 1.6 4.1 2.5 3.4 0.7 5.0 0.5 2.1 0.2 0.5 0.5 2.4 3.4 0.9 0.5 0.8 4.8 0.2 1.9 1.2 0.2 1.8 1.7 2.4 0.0 10.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 7.1 0.0 0.0 0.3 0.1 0.7 10.2 0.0 0.3 0.0 1.6 0.1 19.2 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 3.2 4.4 4.2 3.5 2.8 4.9 2.5 3.4 4.8 2.4 46.9 22.4 8.2 150.5 0.0 2.7 1.4 0.0 1.2 183.8 0.8 0.5 1.5 21.5 2.8 55.2 112.6 23.5 0.1 0.4 7.9 7.0 1.2 4.9 22.4 42.6 41.7 0.0 56.6 2.2 4.3 8.1 0.5 18.8 0.0 6.1 28.2 1.3 2.2 208.6 494.3 0.8 0.0 1.5 2.9 0.5 24.2 0.5 12.4 105.9 0.0 20.7 0.0 262.4 5.4 5.5 6.8 1.5 0.1 7.7 0.1 8.8 0.1 9.3 0.0 10.6 5.0 1.6 1.1 0.6 2.4 51.9 0.8 21.5 1.2 1.1 TIMP1 "CLGI, EPO, TIMP" ENSG00000102265 "TIMP metallopeptidase inhibitor 1" P01033 X 47582408-47586789 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 2277.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 2325.3;Hepatic stellate cells: 2681.5;Langerhans cells: 2307.7;Leydig cells: 1776.0;Macrophages: 1705.0;Peritubular cells: 1561.7;Smooth muscle cells: 2043.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 3225.4;ASC TERT1: 4323.2;fHDF/TERT166: 2762.5;HSkMC: 2960.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022360, HPA053417" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 127000000 520000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "CAB022360: , HPA053417: AB_2682142" "unprognostic (5.86e-3)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.68e-2)" "unprognostic (1.81e-2)" "unprognostic (1.07e-3)" "unprognostic (4.99e-2)" "unprognostic (8.24e-3)" "unprognostic (9.12e-3)" "unprognostic (9.69e-2)" "unprognostic (9.10e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (2.90e-11)" "unprognostic (1.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (2.66e-1)" 1043.9 895.8 110.6 1713.4 110.5 122.2 253.0 114.1 329.6 630.5 160.0 228.0 68.3 342.1 237.4 130.8 570.2 1220.1 995.3 113.5 119.9 469.6 458.6 1221.2 150.4 132.9 125.2 820.8 170.1 224.1 510.7 589.3 130.1 749.1 204.0 25.9 518.6 412.7 61.8 132.4 180.0 741.1 118.9 239.9 208.9 267.7 286.5 80.3 340.0 78.9 119.7 2277.2 303.3 115.6 194.7 295.9 150.4 1850.9 3225.4 4323.2 36.4 2079.0 1728.4 632.5 514.0 118.9 360.1 1.8 269.6 2762.5 355.3 187.2 82.9 896.0 394.8 387.0 193.8 204.1 191.7 174.9 2097.2 136.6 2440.9 2960.8 227.7 1951.9 410.1 743.6 292.1 0.7 315.8 142.9 1088.6 343.1 2.5 518.0 166.8 229.8 647.9 2.5 318.3 173.8 1038.8 120.4 2.5 8.6 1243.6 8.2 276.9 277.6 15.3 257.6 284.8 943.7 1012.1 1108.3 206.3 58.8 135.0 7.4 2688.9 322.6 634.2 331.9 488.4 8.3 139.4 853.2 137.8 21.9 224.6 122.9 511.4 10.1 73.0 65.4 504.5 88.4 817.9 15.0 104.0 431.4 110.6 110.5 114.1 329.6 113.5 119.9 132.9 125.2 130.1 118.9 286.5 115.6 145.9 109.0 170.1 6.2 57.5 231.2 591.5 937.3 132.6 25.4 147.8 133.2 22.5 374.6 355.5 132.4 0.0 25.2 59.3 53.6 0.0 538.6 21.6 34.7 511.9 772.1 277.2 102.7 0.4 411.3 280.1 2325.3 53.5 66.7 491.4 163.7 2681.5 345.1 329.7 0.0 0.4 73.0 297.0 741.4 2307.7 86.9 1776.0 1705.0 512.3 6.5 289.0 141.7 73.2 8.5 0.6 802.1 42.4 1561.7 257.4 741.4 1.1 12.9 109.1 8.4 690.2 304.1 2043.5 52.8 10.6 25.8 174.7 45.0 126.5 231.9 50.5 513.7 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1663.5;Fibroblasts: 967.5;Leydig cells: 1398.6;Peritubular cells: 1934.1;Sertoli cells: 2327.1;Smooth muscle cells: 1116.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 502.6;BJ: 1173.0;BJ hTERT+: 514.7;fHDF/TERT166: 1073.7;WM-115: 893.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (4.98e-2)" "unprognostic (1.77e-3)" "unprognostic (1.60e-1)" "unprognostic (8.53e-4)" "unprognostic (1.67e-2)" "unprognostic (1.05e-2)" "unprognostic (7.01e-2)" "unprognostic (3.22e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (1.90e-5)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.66e-3)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (3.11e-2)" 805.5 288.7 71.7 41.4 74.9 1.1 556.9 68.7 72.6 376.1 221.0 190.4 30.5 393.3 230.4 168.1 373.9 153.5 532.8 64.3 79.2 248.0 92.0 625.1 69.5 83.2 86.7 116.2 81.1 139.5 139.1 999.5 76.0 178.8 81.2 31.7 178.7 341.1 128.1 170.3 122.1 379.6 70.3 187.2 152.1 64.1 106.2 41.1 340.1 325.9 28.8 197.4 261.1 59.5 19.6 0.0 16.9 2.7 502.6 280.6 1.0 1173.0 514.7 94.1 110.8 20.5 0.3 0.1 28.1 1073.7 3.6 18.3 3.2 48.4 135.0 0.1 14.3 147.4 23.5 52.4 197.4 0.1 59.7 47.4 120.4 166.9 9.5 3.4 0.0 0.0 0.1 0.9 44.6 1.2 0.4 5.0 2.5 0.0 0.8 0.1 3.4 0.4 2.1 97.0 12.5 16.8 24.1 0.5 322.9 266.6 0.7 1.3 0.0 7.9 25.2 245.9 19.1 0.2 0.4 0.4 232.3 0.2 893.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.7 74.9 68.7 72.6 64.3 79.2 83.2 86.7 76.0 70.3 106.2 59.5 1663.5 365.4 35.9 101.9 5.3 77.4 766.2 49.5 10.2 4.0 31.2 177.2 279.9 14.3 22.2 51.5 4.2 492.2 4.6 0.3 3.9 2.5 14.9 27.9 747.6 677.3 1.8 35.3 26.1 0.7 433.7 967.5 21.4 23.9 89.2 11.4 743.9 102.0 109.2 3.3 15.7 0.0 24.4 39.3 95.0 57.7 1398.6 28.6 76.5 116.2 0.7 146.6 0.0 52.3 0.8 0.9 0.0 1934.1 9.5 159.5 0.0 15.5 8.5 5.5 2327.1 339.2 1116.6 6.2 7.0 14.3 56.4 809.0 21.5 4.8 0.7 163.4 TIMP4 ENSG00000157150 "TIMP metallopeptidase inhibitor 4" Q99727 3 12153068-12158912 "Plasma proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 177.7;breast: 119.6" "Cell type enriched" "Detected in many" 10 "Adipocytes: 363.9" "Cancer enriched" "Detected in many" 13 "glioma: 66.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 212.9;ASC TERT1: 53.0;HSkMC: 91.9;NTERA-2: 50.7;U-87 MG: 53.6" "Region enhanced" "Detected in all" "cerebellum: 106.1" "Region enriched" "Detected in all" 9 "cerebellum: 47.7" "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.99e-2)" "unprognostic (5.14e-3)" "unprognostic (1.02e-2)" "unprognostic (2.10e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-4)" "unprognostic (9.33e-3)" "unprognostic (4.26e-3)" "unprognostic (1.36e-1)" "unprognostic (1.74e-2)" "unprognostic (3.78e-1)" "unprognostic (6.81e-2)" "unprognostic (4.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (6.66e-5)" "unprognostic (2.86e-1)" 177.7 8.3 7.7 3.9 8.4 0.6 119.6 49.6 7.2 9.3 3.9 12.1 1.4 8.1 1.0 2.9 6.8 4.4 31.0 6.8 8.8 2.8 1.1 6.6 0.6 13.7 8.6 3.8 4.0 1.4 12.3 9.9 11.7 5.5 4.3 1.0 8.9 2.3 16.7 7.7 11.0 4.4 11.3 3.4 9.2 0.7 7.1 2.0 23.1 30.1 0.1 9.8 8.7 11.6 0.7 24.2 0.7 0.0 212.9 53.0 26.4 0.8 8.9 1.0 1.3 0.5 0.1 0.0 2.2 0.9 0.8 0.9 0.0 0.8 0.4 1.0 0.0 0.0 12.7 0.9 33.2 0.0 0.1 91.9 2.2 5.8 0.2 1.6 0.0 0.0 0.5 17.3 0.2 0.6 0.0 0.0 50.7 0.0 6.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 5.0 0.0 0.0 6.1 0.0 0.0 1.0 0.1 0.0 0.6 0.9 0.0 0.1 0.0 53.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 8.4 49.6 7.2 6.8 8.8 13.7 8.6 11.7 11.3 7.1 11.6 363.9 0.0 0.0 0.0 0.4 0.1 1.3 0.3 0.6 0.4 12.4 2.8 7.0 0.0 0.2 0.0 0.0 0.4 1.4 1.3 0.0 0.6 1.6 0.2 2.1 33.6 6.6 5.3 0.1 2.6 2.7 15.7 0.0 0.0 0.0 0.2 22.5 0.0 3.4 0.0 0.2 2.8 0.0 1.2 0.3 7.5 12.2 0.8 3.6 0.0 0.0 0.7 0.0 9.0 0.1 4.6 4.8 2.6 0.0 4.2 2.7 0.5 5.5 0.0 32.9 3.1 29.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 2.0 2.2 TINAG ENSG00000137251 "Tubulointerstitial nephritis antigen" Q9UJW2 6 54307859-54390142 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 110.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 48.6;Distal tubular cells: 23.5;Proximal enterocytes: 72.5;Proximal tubular cells: 207.1" "Cancer enriched" "Detected in some" 4 "renal cancer: 15.8" "Group enriched" "Detected in some" 6 "medulla oblongata: 1.7;pons: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 33 "RPTEC TERT1: 91.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035427, HPA073753" Approved "Secreted to extracellular matrix" NA NA 40000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035427: AB_10601822, HPA073753: " "unprognostic (7.62e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (7.27e-2)" "unprognostic (5.99e-3)" "prognostic favorable (8.75e-5)" "unprognostic (7.10e-2)" 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 14.0 11.7 0.0 0.0 0.0 0.0 1.7 0.1 0.2 0.0 110.4 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 13.8 0.0 0.0 0.0 0.2 0.0 14.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 91.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 1.7 0.1 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.3 0.0 0.0 0.0 48.6 23.5 0.0 1.0 0.1 0.0 0.0 9.7 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 15.3 0.0 0.0 0.0 72.5 207.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.3 0.0 18.4 0.0 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TLL2 ENSG00000095587 "Tolloid like 2" Q9Y6L7 10 96364608-96513926 "Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;heart muscle: 3.6;tongue: 1.9" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 82.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "RPTEC TERT1: 20.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.28e-2)" "unprognostic (7.54e-4)" "unprognostic (1.50e-1)" "unprognostic (3.31e-3)" "unprognostic (2.67e-1)" "unprognostic (2.14e-3)" "unprognostic (1.31e-2)" "unprognostic (3.52e-4)" "unprognostic (7.08e-2)" "unprognostic (2.50e-1)" "unprognostic (6.71e-2)" "unprognostic (3.37e-2)" "unprognostic (4.98e-4)" "unprognostic (2.90e-1)" "unprognostic (8.41e-2)" "unprognostic (1.95e-4)" "unprognostic (2.30e-1)" 0.0 0.1 1.3 0.1 1.5 0.2 0.0 0.6 1.7 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.3 3.6 1.2 1.3 0.0 0.0 0.0 0.1 2.6 1.0 0.1 0.2 0.0 0.4 0.1 2.9 0.1 0.1 0.2 0.2 0.0 0.9 0.0 0.3 0.1 2.2 0.1 0.3 0.1 4.7 0.0 0.1 1.9 0.0 0.0 0.0 2.0 0.2 0.1 0.4 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.1 0.2 0.1 0.2 0.1 0.0 2.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.6 0.1 0.1 0.4 0.0 20.1 0.0 0.7 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 0.6 1.7 1.2 1.3 2.6 1.0 2.9 2.2 4.7 2.0 0.4 0.0 1.1 0.3 0.7 0.1 0.5 1.9 0.0 0.0 0.0 0.0 5.5 1.5 1.0 0.0 0.0 2.4 0.1 0.0 0.0 0.2 6.9 0.2 0.1 1.4 0.0 0.0 1.9 0.6 0.1 2.4 1.5 0.5 0.0 82.4 0.0 0.0 0.3 0.0 5.6 1.7 2.0 0.3 1.4 5.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.5 18.6 0.7 0.0 0.0 1.4 0.8 1.0 0.2 0.2 0.0 0.0 0.7 0.4 0.2 2.6 0.0 0.4 3.4 0.3 0.1 0.2 0.6 TMEFF2 "CT120.2, HPP1, TENB2, TPEF, TR" ENSG00000144339 "Transmembrane protein with EGF like and two follistatin like domains 2" Q9UIK5 2 191949043-192194933 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 33.3;prostate: 36.6;seminal vesicle: 13.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 416.1;Inhibitory neurons: 382.0;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 1337.5" "Cancer enriched" "Detected in some" 21 "prostate cancer: 57.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 36.9;LHCN-M2: 107.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015587 Approved "Secreted in male reproductive system" NA NA "Cluster 65: Brain - Ion transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA015587: AB_1858069" "unprognostic (2.12e-3)" "unprognostic (5.37e-1)" "unprognostic (3.10e-1)" "unprognostic (5.89e-7)" "unprognostic (4.96e-2)" "unprognostic (1.27e-1)" "unprognostic (8.82e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (5.55e-2)" "unprognostic (2.09e-2)" "unprognostic (3.79e-2)" "unprognostic (4.17e-3)" "unprognostic (1.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" 0.3 2.3 30.2 0.1 25.8 0.0 0.3 16.0 26.6 0.1 5.8 0.9 0.6 0.0 8.1 1.2 0.1 1.7 1.8 28.5 26.9 0.0 0.0 0.1 0.0 21.5 23.5 0.2 0.0 0.0 0.3 0.0 22.4 36.6 1.5 3.3 0.1 13.3 0.3 0.2 0.6 0.1 16.6 0.0 0.9 0.7 26.3 0.0 0.2 0.6 0.1 0.8 0.5 33.3 0.0 0.9 36.9 0.0 5.6 5.8 0.1 0.1 0.7 1.8 2.2 0.0 0.0 0.0 0.0 10.3 4.5 0.0 2.3 0.0 7.1 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.0 15.6 0.0 2.0 10.8 9.0 0.1 0.0 0.0 0.0 107.1 0.0 0.0 0.1 2.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.2 2.8 0.0 0.0 0.0 7.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 25.8 16.0 26.6 28.5 26.9 21.5 23.5 22.4 16.6 26.3 33.3 0.1 0.0 0.0 11.8 0.0 0.1 0.1 0.0 0.0 16.6 0.0 0.0 1.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.3 0.0 0.0 416.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.6 382.0 0.5 0.0 0.0 0.7 2.3 26.4 0.0 0.0 11.2 0.0 0.6 0.0 210.6 1337.5 0.0 0.0 8.6 0.0 5.7 0.1 0.0 0.0 1.6 6.6 24.6 0.6 1.2 2.6 0.3 0.3 0.0 0.4 0.0 0.0 0.1 TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447463-68497604 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 89.5;esophagus: 220.2;salivary gland: 56.7;vagina: 156.3" "Cell type enriched" "Detected in some" 14 "Ionocytes: 476.0" "Group enriched" "Detected in many" 6 "cervical cancer: 22.0;head and neck cancer: 25.3;lung cancer: 11.5;urothelial cancer: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.5;OE19: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043816, HPA051062" Enhanced Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA043816: , HPA051062: AB_2681329" "unprognostic (2.53e-1)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" "unprognostic (9.14e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (2.22e-1)" "unprognostic (9.70e-3)" "unprognostic (2.16e-1)" "unprognostic (3.74e-2)" "unprognostic (4.03e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 89.5 0.0 0.0 0.0 0.0 18.2 220.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 2.2 0.0 0.0 56.7 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 24.5 6.5 156.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 12.9 0.7 0.0 0.0 0.5 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.3 6.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 476.0 0.0 0.3 1.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.2 6.6 0.3 1.1 0.7 0.0 0.0 32.6 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TMPRSS4 "MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.7;intestine: 43.5;urinary bladder: 74.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.7;Club cells: 103.5;Distal enterocytes: 187.9;Squamous epithelial cells: 119.2;Urothelial cells: 258.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Immune cell enriched" "Detected in single" 7 "basophil: 2.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.1" "Group enriched" "Detected in some" 5 "CAPAN-2: 103.7;HaCaT: 39.2;OE19: 141.6;RPTEC TERT1: 70.6;RT4: 95.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA006238: AB_1080316" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-2)" "unprognostic (5.50e-2)" "unprognostic (8.17e-3)" "unprognostic (1.95e-2)" "unprognostic (2.41e-1)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-2)" "unprognostic (9.96e-3)" 0.2 0.0 0.1 6.1 0.1 0.8 0.3 1.8 0.3 16.6 0.3 43.5 25.4 2.1 3.2 108.7 1.0 14.3 0.2 0.1 0.0 21.1 0.2 1.4 0.2 0.1 0.0 0.1 0.3 0.0 0.2 0.1 0.2 7.8 42.9 0.4 6.5 0.2 0.2 4.1 22.4 1.5 0.0 0.2 31.4 1.1 0.2 1.1 0.2 0.1 14.9 74.6 16.7 0.3 18.5 0.1 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.7 103.7 0.1 3.5 0.0 0.1 39.2 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 3.4 0.3 0.0 1.3 0.3 4.5 0.1 141.6 0.0 0.1 0.1 0.2 70.6 95.9 0.1 0.1 0.0 8.4 0.1 0.2 0.5 0.1 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 1.8 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 1.7 0.0 0.4 1.1 35.2 101.7 38.1 0.0 0.0 0.0 0.7 0.0 103.5 11.0 0.0 0.2 0.0 187.9 0.0 1.5 3.0 45.3 4.6 0.8 4.2 0.0 0.2 7.3 3.0 0.5 53.5 66.4 5.7 0.0 0.0 0.1 0.2 0.0 0.2 55.3 34.6 0.3 0.3 2.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 52.6 67.5 0.0 2.7 17.5 55.2 2.4 69.4 0.0 0.0 0.0 4.7 0.0 0.1 119.2 6.3 0.3 0.5 0.0 71.2 258.6 TNC "DFNA56, HXB, MGC167029, TN" ENSG00000041982 "Tenascin C" P24821 9 115019575-115118257 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 376.2" "Cell type enhanced" "Detected in many" "Astrocytes: 160.3;Basal prostatic cells: 72.1;Basal respiratory cells: 150.6;Basal squamous epithelial cells: 126.3;Prostatic glandular cells: 69.2;Smooth muscle cells: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 798.5;hTEC/SVTERT24-B: 634.4;U-138 MG: 526.0;U-251 MG: 484.5;U-87 MG: 711.8;WM-115: 1253.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004592, HPA004823" Approved "Secreted to extracellular matrix" NA NA 560000000 840000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB004592: AB_628342, HPA004823: AB_1080243" "unprognostic (5.46e-2)" "unprognostic (3.76e-2)" "unprognostic (7.57e-2)" "unprognostic (1.69e-1)" "unprognostic (9.20e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (7.86e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-2)" "unprognostic (1.82e-1)" "unprognostic (4.87e-3)" "unprognostic (1.79e-2)" "unprognostic (1.92e-2)" "unprognostic (7.60e-2)" "unprognostic (1.97e-3)" 61.0 4.7 16.4 170.4 28.5 0.9 41.2 14.0 9.8 43.6 3.0 174.3 16.7 106.8 12.2 23.9 25.5 14.1 32.6 15.6 34.3 82.0 7.7 54.2 39.8 20.3 43.8 5.3 4.8 2.3 7.2 4.0 28.0 39.1 28.3 4.8 19.8 33.3 6.2 25.9 56.5 376.2 15.0 40.8 62.4 4.8 65.4 17.1 13.3 3.2 22.6 96.7 15.9 20.5 25.1 6.0 6.9 1.3 37.5 10.1 0.1 205.7 798.5 425.4 203.6 5.3 55.3 0.0 32.8 291.7 6.9 89.9 0.0 12.0 241.3 0.4 2.2 0.0 4.8 0.0 0.7 0.4 3.9 6.2 1.7 634.4 289.9 42.9 0.1 0.0 0.0 5.2 11.4 0.0 0.1 0.3 65.2 0.9 85.3 0.2 451.9 0.1 373.3 0.1 0.6 5.9 91.4 0.2 19.3 140.9 1.0 1.4 0.1 526.0 88.4 94.2 484.5 14.3 0.4 0.4 711.8 0.6 1253.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 16.4 28.5 14.0 9.8 15.6 34.3 20.3 43.8 28.0 15.0 65.4 20.5 0.7 12.8 43.5 160.3 0.4 12.1 72.1 150.6 126.3 0.1 9.3 33.3 1.4 0.0 14.8 1.8 0.0 1.1 0.3 0.0 0.0 25.8 15.4 6.7 47.8 11.1 0.0 0.0 7.0 4.5 0.6 19.0 0.0 24.9 2.5 0.5 6.1 0.0 1.2 0.0 0.9 0.0 0.0 0.6 4.7 18.4 3.4 0.9 5.4 1.9 0.1 1.3 0.0 4.0 0.8 3.9 0.0 0.4 0.3 69.2 0.0 0.3 3.5 0.2 0.0 1.3 58.9 0.4 0.2 4.8 4.5 1.0 2.6 0.1 0.1 5.8 TNF "DIF, TNF-alpha, TNFA, TNFSF2" ENSG00000232810 "Tumor necrosis factor" P01375 6 31575565-31578336 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in many" "B-cells: 90.7;dendritic cells: 60.8;Langerhans cells: 72.7;Macrophages: 108.3;T-cells: 100.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 68.0" "Group enriched" "Detected in all" 5 "granulocytes: 20.8;monocytes: 68.0;T-cells: 36.6" "Group enriched" "Detected in some" 8 "HDLM-2: 103.7;NB-4: 214.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB078469 Supported "Secreted to blood" NA NA 10100 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "CAB078469: AB_908070" "unprognostic (1.93e-1)" "unprognostic (1.07e-2)" "unprognostic (3.85e-2)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-2)" "unprognostic (1.67e-1)" "unprognostic (3.46e-1)" "unprognostic (1.19e-2)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-2)" "unprognostic (1.82e-1)" "unprognostic (9.85e-3)" "unprognostic (1.09e-1)" "unprognostic (2.04e-1)" 1.4 0.5 0.0 3.3 0.0 12.7 0.5 0.0 0.1 0.1 0.0 0.9 0.0 1.5 0.0 0.7 0.3 0.6 2.6 0.1 0.0 1.2 0.6 3.6 1.6 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 1.5 2.4 0.2 0.1 6.5 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.8 0.0 0.0 0.0 0.0 103.7 0.0 19.4 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 214.4 0.0 0.0 0.0 9.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 10.1 0.0 23.2 39.5 36.6 7.2 17.2 13.9 7.6 7.0 5.0 5.2 20.8 2.0 68.0 4.3 13.6 14.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 3.0 0.0 90.7 8.4 1.2 12.1 4.6 0.2 17.4 20.4 2.0 2.8 4.0 0.0 2.1 0.9 60.8 0.5 0.0 7.4 0.1 15.5 5.9 10.7 0.0 0.0 0.0 3.3 1.7 2.0 1.5 30.5 12.6 0.0 1.8 0.1 36.5 0.0 0.0 0.4 10.2 14.1 72.7 0.0 0.3 108.3 5.4 1.9 3.4 0.1 2.1 0.0 0.1 14.3 0.0 0.0 10.4 1.7 0.0 0.1 3.0 0.2 0.0 0.6 4.0 0.0 0.0 1.3 4.1 1.1 100.0 0.0 0.4 0.3 TNFAIP6 "TSG-6, TSG6" ENSG00000123610 "TNF alpha induced protein 6" P98066 2 151357592-151380046 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "urinary bladder: 196.0" "Cell type enhanced" "Detected in many" "Early spermatids: 443.9;Fibroblasts: 302.3;Langerhans cells: 137.4;Melanocytes: 74.7" "Cancer enhanced" "Detected in many" "renal cancer: 27.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "neutrophil: 183.0" "Lineage enriched" "Detected in many" 22 "granulocytes: 183.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 67.5;HHSteC: 40.3;hTEC/SVTERT24-B: 54.9;SH-SY5Y: 21.6;U-2197: 44.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB032719, HPA050884" Uncertain "Secreted to blood" NA NA 100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB032719: AB_2204650, HPA050884: AB_2681261" "unprognostic (1.31e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (8.66e-2)" "unprognostic (2.51e-2)" "unprognostic (1.15e-3)" "unprognostic (3.26e-3)" "unprognostic (3.75e-4)" "unprognostic (4.49e-3)" "unprognostic (1.22e-1)" "unprognostic (1.90e-1)" "unprognostic (5.87e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.59e-4)" "unprognostic (1.06e-2)" "unprognostic (1.25e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (9.16e-5)" 15.6 0.5 1.9 27.6 2.2 7.6 11.1 1.5 2.8 9.2 1.2 6.3 0.7 2.0 0.3 2.2 2.2 19.8 15.4 1.7 2.2 0.4 1.2 11.0 0.6 1.6 2.2 0.5 1.2 0.3 0.4 1.8 1.9 3.2 2.8 0.0 3.4 0.9 1.7 2.7 2.2 7.2 1.6 3.0 4.0 10.6 2.6 1.4 1.6 2.8 0.5 196.0 1.6 2.3 0.0 0.0 0.0 0.0 3.8 15.5 0.0 2.5 67.5 2.5 12.4 0.0 0.0 0.0 0.8 1.1 1.4 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.3 0.0 40.3 0.0 0.0 19.5 0.0 54.9 3.8 2.3 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.3 0.0 15.5 0.0 1.1 0.0 0.0 0.0 0.0 21.6 0.5 0.0 0.0 0.4 0.0 0.0 0.0 2.2 4.4 44.3 0.8 0.0 0.0 0.0 4.8 0.7 3.3 0.0 8.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 183.0 0.0 2.1 0.0 0.0 2.5 1.9 2.2 1.5 2.8 1.7 2.2 1.6 2.2 1.9 1.6 2.6 2.3 4.5 3.2 1.7 1.3 1.1 64.7 0.9 11.1 0.0 0.0 1.5 1.4 2.2 0.0 1.5 0.0 0.0 0.1 0.3 0.1 0.0 2.8 443.9 2.9 2.7 7.3 0.0 0.8 0.7 0.0 0.9 302.3 0.5 10.6 2.5 0.0 1.4 0.0 1.4 0.0 0.4 0.0 0.0 6.9 137.4 38.5 2.5 49.6 74.7 1.9 5.9 0.0 0.0 13.6 7.1 1.5 0.0 0.4 1.4 3.0 0.0 0.2 0.2 0.0 0.0 40.6 45.5 10.7 1.9 1.0 53.0 1.8 6.0 0.3 0.0 3.8 TNFRSF11B "OCIF, OPG, TR1" ENSG00000164761 "TNF receptor superfamily member 11b" O00300 8 118923557-118951885 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 29.9;thyroid gland: 101.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 134.3;Collecting duct cells: 73.5;Ductal cells: 32.7;Proximal tubular cells: 117.3" "Cancer enhanced" "Detected in all" "renal cancer: 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 40 "dendritic cells: 3.9" "Group enriched" "Detected in many" 4 "BJ: 546.7;BJ hTERT+: 2013.0" "Low region specificity" "Detected in all" CAB034939 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "CAB034939: " "unprognostic (1.39e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (5.27e-2)" "unprognostic (2.33e-2)" "unprognostic (4.27e-3)" "unprognostic (1.10e-3)" "unprognostic (1.21e-3)" "unprognostic (5.50e-2)" "unprognostic (9.94e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (2.43e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.32e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (3.88e-4)" 3.3 3.3 2.6 5.3 3.1 0.0 2.6 2.6 4.1 1.1 3.5 2.5 1.4 10.2 0.5 0.4 1.4 5.8 9.4 2.5 2.7 29.9 14.2 9.4 7.0 5.0 3.0 0.3 1.8 0.5 1.8 4.9 3.3 1.6 3.5 0.3 1.4 1.0 0.4 0.5 2.2 2.6 3.1 2.6 1.2 0.1 3.0 1.3 101.8 0.8 2.9 10.7 0.3 3.8 0.0 0.9 8.6 0.0 27.5 5.3 0.0 546.7 2013.0 25.9 7.2 6.3 1.1 0.0 143.7 302.4 0.0 5.6 0.0 0.0 13.2 0.1 0.0 0.0 23.1 0.0 3.6 0.0 0.0 2.9 0.0 26.7 0.0 10.9 0.3 0.0 0.0 0.0 73.8 13.6 0.0 0.1 0.9 2.6 3.3 0.0 1.0 0.0 23.6 0.0 1.3 0.0 4.8 0.2 0.0 0.3 0.0 0.1 1.2 16.9 8.6 10.1 1.2 0.6 0.0 0.1 2.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 2.6 3.1 2.6 4.1 2.5 2.7 5.0 3.0 3.3 3.1 3.0 3.8 2.1 3.2 0.0 7.2 0.7 2.2 0.6 1.4 0.0 0.2 134.3 4.1 3.8 22.8 1.0 73.5 0.0 0.0 0.2 2.5 9.8 32.7 0.1 0.6 1.4 7.4 9.5 0.0 0.8 1.3 0.2 9.4 0.0 1.7 0.0 0.0 4.6 2.0 0.5 0.0 0.3 9.2 2.0 0.3 3.9 0.3 0.3 1.1 0.0 0.0 8.3 1.2 0.0 3.0 0.3 9.2 0.8 0.0 0.0 6.8 1.1 117.3 0.1 0.1 0.0 0.4 4.3 0.1 0.3 0.0 1.1 0.0 0.4 0.0 2.8 0.3 TNFRSF18 "AITR, CD357, GITR" ENSG00000186891 "TNF receptor superfamily member 18" Q9Y5U5 1 1203508-1206592 "CD markers, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 189.0;dendritic cells: 72.2;Langerhans cells: 86.4;Melanocytes: 49.8;Plasma cells: 55.3;Suprabasal keratinocytes: 150.6;T-cells: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cell: 184.5;T-reg: 71.8" "Group enriched" "Detected in many" 11 "NK-cells: 184.5;T-cells: 71.8" "Group enriched" "Detected in some" 12 "RPMI-8226: 225.6;SCLC-21H: 152.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008025 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA008025: AB_1849696" "unprognostic (1.20e-3)" "unprognostic (4.61e-2)" "unprognostic (4.59e-2)" "prognostic favorable (7.72e-6)" "unprognostic (2.73e-4)" "prognostic favorable (4.12e-4)" "unprognostic (3.43e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.40e-11)" "unprognostic (1.02e-3)" "unprognostic (2.39e-1)" "unprognostic (3.74e-1)" "unprognostic (2.08e-1)" 1.9 0.6 1.1 7.3 1.3 2.9 2.4 2.5 3.1 11.1 0.7 6.0 7.2 1.4 0.0 6.3 1.4 0.9 0.5 1.0 0.6 2.8 0.9 4.6 5.5 1.3 0.6 0.3 0.3 9.4 4.9 0.3 1.3 2.8 1.5 0.0 5.6 0.6 0.8 38.5 7.1 0.3 0.6 9.0 5.2 0.9 0.9 1.9 1.4 0.0 3.8 2.0 3.3 1.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 1.2 0.1 0.5 16.1 0.1 0.1 225.6 0.3 0.0 152.8 0.2 0.0 0.6 0.0 0.0 8.2 0.1 0.0 0.0 0.3 0.2 0.0 0.9 0.3 0.2 0.6 0.1 0.0 0.2 0.2 0.0 6.8 0.1 12.6 4.6 28.9 4.4 0.1 11.5 0.9 1.5 0.8 184.5 0.1 0.3 71.8 6.7 1.1 1.3 2.5 3.1 1.0 0.6 1.3 0.6 1.3 0.6 0.9 1.2 11.2 0.0 1.3 0.3 23.5 189.0 12.5 15.5 16.5 0.0 5.0 3.0 2.9 0.0 3.2 0.0 0.0 0.0 72.2 0.3 0.0 0.8 0.0 1.2 1.2 4.1 3.5 0.0 2.0 0.6 1.3 4.7 1.1 2.9 45.7 0.0 0.7 0.0 0.8 0.0 0.3 0.2 20.3 0.3 86.4 0.0 0.0 5.4 49.8 0.0 12.7 0.0 21.6 0.5 0.3 0.4 0.0 0.0 55.3 10.1 0.1 0.1 0.8 0.0 0.0 6.2 2.2 0.0 0.0 0.3 150.6 0.0 75.7 0.0 0.8 7.0 TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 507.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" NA NA 17700 570000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010309: AB_2206639, HPA004102: AB_1846232" "unprognostic (2.19e-2)" "unprognostic (3.76e-2)" "unprognostic (8.14e-2)" "prognostic favorable (8.22e-4)" "unprognostic (3.07e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.50e-1)" "unprognostic (1.41e-3)" "unprognostic (1.00e-1)" "unprognostic (8.05e-2)" "unprognostic (4.78e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (5.14e-3)" "unprognostic (1.74e-1)" 166.5 133.3 33.7 76.7 34.4 42.4 120.0 35.3 38.6 105.0 47.8 114.1 101.5 111.8 23.0 105.6 106.7 88.8 80.6 32.4 40.3 94.5 176.5 130.7 38.1 45.7 40.4 90.6 57.3 53.7 57.3 82.4 39.6 86.9 56.4 3.5 76.0 46.3 91.0 103.7 109.5 97.5 40.4 111.3 84.4 22.6 39.7 39.2 97.4 63.1 36.1 113.2 113.2 37.4 40.2 296.4 40.9 60.2 277.7 282.0 75.7 82.2 143.0 108.2 93.9 34.7 153.6 3.7 28.9 179.3 85.6 107.1 12.9 96.4 74.1 0.8 25.3 20.3 79.2 82.2 245.5 104.4 66.9 291.8 94.4 90.2 131.4 250.4 134.1 42.0 33.7 29.8 126.3 57.1 34.0 100.0 102.1 146.1 87.6 27.9 66.6 32.4 83.7 70.7 0.1 2.1 117.8 60.9 62.5 103.6 16.4 111.4 146.0 84.6 71.7 64.7 78.4 0.1 10.6 12.8 100.5 95.9 107.0 17.1 165.8 93.5 62.2 130.4 60.0 0.5 25.1 51.0 123.7 0.4 22.3 34.0 507.2 9.7 111.5 31.6 26.2 117.3 33.7 34.4 35.3 38.6 32.4 40.3 45.7 40.4 39.6 40.4 39.7 37.4 102.0 51.3 37.1 15.3 4.8 123.0 115.8 127.3 81.4 0.4 50.1 35.9 9.3 67.2 70.8 27.6 0.0 62.0 35.5 204.0 15.6 98.7 1.2 25.5 66.5 111.8 33.6 30.1 4.6 119.4 120.2 109.3 43.8 42.3 7.6 27.6 159.2 145.0 176.4 0.0 1.3 56.8 32.6 146.7 113.4 5.4 102.2 102.4 71.2 32.8 127.1 15.9 104.0 11.1 0.9 116.6 239.4 65.8 4.2 141.2 227.5 96.9 30.8 0.7 124.9 64.1 89.4 1.3 1.1 57.0 134.7 148.6 31.2 21.5 57.4 140.1 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNFRSF6B "DcR3, M68, TR6" ENSG00000243509 "TNF receptor superfamily member 6b" O95407 20 63696652-63698684 "Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 51.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 21.6" "Lineage enriched" "Detected in many" 16 "dendritic cells: 21.6" "Group enriched" "Detected in some" 4 "HBEC3-KT: 28.3;RPTEC TERT1: 110.7;TIME: 69.0" HPA047154 Approved "Secreted to blood" NA NA 406000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "HPA047154: AB_2679959" 30.9 5.1 14.4 14.3 11.9 0.2 24.7 11.5 18.2 7.8 7.4 13.7 0.0 8.0 0.0 11.7 9.6 0.5 7.7 11.4 14.7 16.6 5.5 51.2 1.2 17.0 12.9 7.3 8.3 0.0 15.4 0.0 16.8 10.6 0.1 0.0 10.2 0.0 7.1 13.8 16.1 0.9 15.0 39.3 9.8 6.8 18.7 0.0 12.3 0.0 3.4 16.0 9.6 11.4 0.0 0.5 0.0 0.0 0.0 0.2 1.5 1.8 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.5 0.0 0.0 9.4 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.8 0.0 0.0 0.0 110.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 69.0 0.0 1.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 1.3 21.6 0.1 0.1 14.4 11.9 11.5 18.2 11.4 14.7 17.0 12.9 16.8 15.0 18.7 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TNFSF10 "Apo-2L, CD253, TL2, TRAIL" ENSG00000121858 "TNF superfamily member 10" P50591 3 172505508-172523475 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 732.8;Exocrine glandular cells: 424.6;Proximal tubular cells: 556.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 265.4;classical monocyte: 133.4;intermediate monocyte: 203.5;neutrophil: 257.1;non-classical monocyte: 213.2" "Group enriched" "Detected in all" 5 "granulocytes: 265.4;monocytes: 213.2" "Cell line enhanced" "Detected in many" "BEWO: 73.1;CAPAN-2: 53.7;HaCaT: 51.5;HMC-1: 244.5;RPTEC TERT1: 122.1" "Low region specificity" "Detected in all" HPA054938 Uncertain "Secreted to blood" NA NA 67400 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA054938: AB_2682643" "unprognostic (9.16e-2)" "unprognostic (2.79e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-3)" "unprognostic (2.52e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (1.32e-1)" "unprognostic (6.27e-2)" 51.0 49.9 9.5 55.4 9.8 14.8 84.5 9.8 17.0 37.3 17.3 76.8 100.3 47.1 19.6 66.4 39.1 45.3 31.7 9.0 9.9 145.1 209.0 177.2 54.7 12.0 10.2 27.1 22.2 77.7 10.4 167.9 11.0 86.7 91.4 1.4 127.9 42.7 20.7 54.6 95.2 26.3 11.0 70.9 47.3 4.8 10.3 34.2 29.3 61.7 46.8 70.3 62.4 10.6 12.4 0.6 0.1 0.2 8.2 6.6 73.1 0.0 0.5 3.7 5.9 0.3 53.7 7.9 34.7 0.0 3.2 51.5 0.3 6.3 0.7 19.6 0.2 0.2 1.5 1.1 0.4 14.7 244.5 8.2 8.0 1.3 0.2 0.0 25.6 1.6 0.3 8.7 0.0 0.1 1.9 19.4 0.3 0.2 0.5 2.9 0.2 3.5 122.1 4.6 0.3 0.5 27.2 1.0 0.6 0.4 15.3 8.0 1.1 0.1 0.2 0.1 0.7 9.3 1.1 9.5 0.6 8.0 0.2 265.4 133.4 14.7 10.9 203.5 15.0 16.7 30.4 16.8 49.1 18.2 21.6 8.5 257.1 49.3 213.2 2.9 36.8 73.6 9.5 9.8 9.8 17.0 9.0 9.9 12.0 10.2 11.0 11.0 10.3 10.6 326.5 70.5 114.4 0.0 26.2 22.0 169.5 398.4 69.4 0.3 146.5 97.3 7.9 84.4 281.1 66.2 0.0 6.6 20.7 294.2 45.0 732.8 4.5 60.5 18.2 247.5 48.3 9.7 0.1 424.6 189.4 69.2 44.9 121.0 257.0 2.4 186.7 75.2 23.5 1.7 0.1 111.3 175.0 79.8 23.7 3.8 18.3 70.5 7.2 52.5 160.3 18.7 52.5 0.0 0.1 244.0 216.4 4.9 23.2 82.7 317.0 556.7 114.5 1.5 0.0 6.5 22.3 0.1 0.3 103.1 25.6 10.9 51.8 19.7 74.3 170.1 TNFSF11 "CD254, ODF, OPGL, RANKL, TRANCE" ENSG00000120659 "TNF superfamily member 11" O14788 13 42562736-42608013 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Cytokine, Developmental protein, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.5;liver: 5.2;lymphoid tissue: 15.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 10.8;Breast myoepithelial cells: 5.1;Ductal cells: 6.2;Early spermatids: 8.0;Late spermatids: 15.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "NK-cell: 13.6" "Lineage enriched" "Detected in many" 7 "NK-cells: 13.6" "Cell line enhanced" "Detected in some" "HSkMC: 2.1;NTERA-2: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009193, HPA045142" Enhanced "Secreted to blood" NA NA 17200 "Cluster 15: NK-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 35: Glandular cells - Unknown function" "CAB009193: , HPA045142: AB_2679231" "unprognostic (3.97e-4)" "unprognostic (1.40e-1)" "unprognostic (9.01e-3)" "unprognostic (3.81e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (7.09e-2)" "unprognostic (7.70e-2)" "unprognostic (2.29e-1)" "unprognostic (1.25e-3)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (3.94e-5)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (5.46e-2)" "unprognostic (7.74e-2)" 0.2 0.0 0.0 4.8 0.0 0.2 4.5 0.0 0.1 0.8 0.2 0.9 0.4 0.1 0.0 0.1 0.0 1.4 0.1 0.0 0.1 0.1 5.2 0.1 15.2 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 1.1 0.0 0.1 1.9 0.0 0.0 0.6 0.5 1.3 0.1 1.5 0.0 0.1 5.0 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.0 0.0 10.8 5.1 0.4 1.5 0.2 0.0 0.0 0.0 2.3 0.0 0.0 6.2 8.0 0.5 0.1 0.1 1.2 0.0 0.2 0.2 0.0 0.2 0.0 0.7 0.0 0.3 0.0 1.0 0.0 0.0 0.7 0.9 0.0 0.0 0.4 15.3 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 3.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 0.0 0.3 0.0 1.8 0.0 0.0 0.0 TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7549058-7557890 "Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 17.7;BJ hTERT+: 18.4;HDLM-2: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" NA NA 853000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA035984: , HPA052967: AB_2682000" "unprognostic (2.96e-3)" "unprognostic (2.96e-1)" "unprognostic (4.71e-2)" "prognostic favorable (5.70e-5)" "unprognostic (5.31e-2)" "unprognostic (7.91e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (6.09e-2)" "unprognostic (6.20e-2)" "unprognostic (8.62e-2)" "unprognostic (3.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (8.74e-2)" "unprognostic (2.38e-1)" 41.6 28.5 57.4 9.8 55.3 3.1 36.6 49.4 66.5 37.6 48.9 68.2 9.7 38.2 7.0 13.9 37.7 15.6 39.6 54.8 50.4 32.9 16.5 37.7 15.8 55.7 54.2 42.7 23.2 11.1 18.0 11.2 53.2 39.4 5.7 2.9 26.1 27.2 16.9 15.8 26.7 13.3 52.8 38.4 38.8 5.6 57.0 4.8 22.9 9.3 5.5 47.1 30.1 52.1 0.0 0.5 0.7 0.0 14.9 17.7 4.0 6.9 18.4 7.7 5.7 0.1 2.5 0.0 5.8 16.3 0.8 1.4 1.4 0.6 1.6 20.3 2.0 0.9 0.4 2.3 12.8 0.0 0.0 15.0 2.6 2.8 0.3 3.0 12.1 0.0 0.0 0.0 7.0 0.0 0.0 0.5 0.6 0.1 7.5 0.1 0.0 0.1 11.6 0.0 0.0 7.9 2.5 0.0 12.6 0.1 1.4 0.6 16.1 15.1 1.1 0.1 8.8 0.0 0.0 0.0 2.4 0.0 10.5 2.6 3.5 11.6 5.1 5.9 6.0 2.9 4.3 3.1 2.2 1.8 4.1 4.2 2.0 2.8 1.5 2.5 4.0 1.1 57.4 55.3 49.4 66.5 54.8 50.4 55.7 54.2 53.2 52.8 57.0 52.1 115.9 9.6 12.2 0.0 20.4 6.1 11.1 1.5 6.8 6.7 21.7 41.7 4.3 17.2 3.4 16.5 0.0 1.6 38.3 2.5 7.9 15.2 0.4 4.1 15.2 33.9 1.2 3.2 0.0 12.1 0.8 42.7 4.6 8.5 34.3 6.8 48.5 3.4 44.3 20.2 0.0 3.4 0.0 59.7 26.8 1.2 50.7 62.1 19.6 0.0 28.6 46.6 40.2 0.0 0.0 8.1 1.7 50.4 3.6 6.7 0.4 39.6 0.6 2.6 59.2 34.4 56.7 0.2 1.1 2.1 7.5 0.8 38.7 9.4 4.1 6.0 TNFSF13 "APRIL, CD256" ENSG00000161955 "TNF superfamily member 13" O75888 17 7558292-7561608 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 141.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 10.4;Basal squamous epithelial cells: 8.0;Erythroid cells: 5.9;Gastric mucus-secreting cells: 11.2;Macrophages: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 438.1;intermediate monocyte: 420.9" "Group enriched" "Detected in all" 12 "dendritic cells: 283.5;granulocytes: 158.9;monocytes: 438.1" "Cell line enhanced" "Detected in many" "EFO-21: 43.6;RPMI-8226: 39.9;RPTEC TERT1: 110.6;U-937: 44.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004863 Uncertain "Secreted to blood" NA NA 6770000 35000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "HPA004863: AB_1078187" "unprognostic (2.46e-2)" "unprognostic (2.20e-1)" "unprognostic (3.42e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (3.57e-1)" "unprognostic (3.32e-2)" "unprognostic (3.70e-2)" "unprognostic (3.75e-1)" "unprognostic (1.15e-1)" "unprognostic (6.95e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.30e-9)" "unprognostic (4.69e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.38e-2)" 27.7 31.6 39.5 37.7 43.7 48.4 29.5 39.7 47.3 33.5 66.7 45.9 74.7 13.3 19.2 12.5 31.8 54.1 18.0 35.3 37.6 55.6 16.2 100.7 33.1 44.8 43.3 24.8 41.1 18.0 19.7 14.7 41.1 22.6 41.9 13.0 141.9 32.1 5.3 10.5 39.5 24.8 40.0 30.6 54.0 4.6 44.8 14.1 27.0 10.1 24.5 26.0 15.5 38.8 20.8 8.3 2.8 5.5 3.2 1.7 3.4 3.7 2.7 1.5 1.3 4.6 12.8 9.1 43.6 3.8 5.2 13.1 0.1 3.6 1.6 16.2 7.0 5.9 18.2 9.7 6.7 5.1 5.9 3.6 3.6 1.0 5.7 8.8 4.7 6.5 4.6 3.5 1.3 3.1 2.3 16.6 2.7 20.3 6.0 16.5 3.4 39.9 110.6 13.5 5.1 4.9 7.2 18.8 2.5 4.1 25.2 12.4 2.4 4.8 5.8 2.1 8.1 0.8 2.8 2.4 1.9 44.1 9.5 75.2 438.1 158.9 0.9 420.9 0.8 13.7 0.5 0.7 283.5 25.0 2.4 1.5 56.9 7.9 265.4 130.8 0.9 257.1 39.5 43.7 39.7 47.3 35.3 37.6 44.8 43.3 41.1 40.0 44.8 38.8 0.2 6.4 10.4 0.0 2.1 0.0 0.2 0.2 8.0 0.1 0.4 0.1 0.0 0.0 2.0 1.8 0.0 0.0 0.1 1.0 0.0 0.4 0.0 0.2 0.1 0.0 1.2 5.9 0.0 0.2 0.0 2.9 11.2 0.4 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 19.5 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.2 0.7 0.3 1.5 0.2 0.0 0.1 0.2 0.0 0.0 2.6 0.0 0.0 0.8 0.1 0.6 0.2 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNFSF14 "CD258, HVEM-L, LIGHT, LTg" ENSG00000125735 "TNF superfamily member 14" O43557 19 6661253-6670588 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 29.0;liver: 107.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 26.3;dendritic cells: 40.5;granulocytes: 26.1;Macrophages: 20.0;NK-cells: 26.8;T-cells: 43.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 199.7" "Group enriched" "Detected in all" 4 "granulocytes: 199.7;T-cells: 61.2" "Cell line enhanced" "Detected in some" "HDLM-2: 16.9;NB-4: 4.9;THP-1: 3.1;U-937: 10.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA012700 Uncertain Approved Vesicles "Secreted to blood" NA NA 41000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012700: AB_1852870" "unprognostic (2.78e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-3)" "unprognostic (3.82e-4)" "unprognostic (4.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (1.05e-2)" "unprognostic (9.23e-2)" "unprognostic (9.22e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (6.07e-13)" "unprognostic (1.09e-1)" "unprognostic (9.56e-3)" "unprognostic (1.75e-1)" "unprognostic (3.62e-2)" 29.0 1.7 2.2 3.1 1.3 1.9 2.7 0.8 6.4 2.1 1.3 2.7 1.8 0.9 0.3 1.8 9.7 1.2 3.8 1.0 1.2 1.3 107.9 4.9 2.5 1.3 1.7 5.1 4.5 0.0 1.1 0.2 1.7 2.0 1.3 0.2 2.2 0.2 0.5 0.6 5.9 1.2 0.9 3.2 2.3 0.6 3.1 1.1 2.8 0.6 2.0 4.1 2.3 1.7 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.5 0.0 0.0 0.0 16.9 0.0 0.0 0.2 1.1 0.0 0.5 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.4 0.0 140.9 17.6 115.3 41.8 4.0 61.2 0.4 17.7 34.5 6.9 1.9 2.8 15.0 199.7 30.7 0.5 0.7 15.9 12.8 2.2 1.3 0.8 6.4 1.0 1.2 1.3 1.7 1.7 0.9 3.1 1.7 0.7 9.6 26.3 0.0 1.6 2.9 0.7 0.9 0.0 0.0 1.1 0.8 0.8 15.7 8.2 0.0 0.0 0.1 40.5 0.0 0.0 4.1 1.2 4.8 2.6 0.9 0.0 0.4 0.1 3.8 0.2 12.4 1.1 18.1 26.1 0.2 1.8 15.8 12.8 0.0 0.1 0.2 0.0 3.4 12.3 0.0 0.3 20.0 3.6 1.0 5.8 0.0 26.8 0.0 0.1 6.0 0.0 0.0 4.8 0.6 0.0 0.4 2.8 0.0 0.0 1.4 1.0 0.2 0.3 0.3 3.3 0.0 43.7 0.0 0.0 0.4 TNFSF15 "MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A" ENSG00000181634 "TNF superfamily member 15" O95150 9 114784652-114806039 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.6;Basal squamous epithelial cells: 14.8;Endometrial ciliated cells: 15.7;Glandular and luminal cells: 28.9;Squamous epithelial cells: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 13.2;hTEC/SVTERT24-B: 8.6;HUVEC TERT2: 16.7;OE19: 16.0;RT4: 16.5;TIME: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012948, HPA046522" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted to blood" NA NA 1110000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA012948: AB_1858024, HPA046522: AB_2679683" "unprognostic (3.41e-1)" "unprognostic (2.06e-2)" "unprognostic (3.76e-1)" "unprognostic (1.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.67e-2)" "unprognostic (1.64e-1)" "unprognostic (2.29e-2)" "unprognostic (5.40e-2)" "unprognostic (1.38e-1)" "unprognostic (7.78e-2)" "unprognostic (2.09e-1)" "unprognostic (8.64e-5)" "unprognostic (1.97e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-3)" "unprognostic (4.46e-3)" 0.8 0.7 0.1 2.5 0.2 0.1 0.9 0.1 0.5 1.5 0.1 2.3 9.5 1.0 0.9 1.2 0.9 1.9 0.0 0.1 0.2 4.5 0.2 4.1 0.8 0.3 0.1 0.1 0.1 0.8 0.1 4.4 0.2 4.1 2.0 0.0 4.8 1.9 0.1 0.6 3.5 2.0 0.0 0.5 2.9 0.1 0.2 0.6 0.9 0.0 1.0 4.7 0.7 0.4 0.5 4.4 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.2 3.0 1.6 0.0 0.0 0.5 13.2 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.0 16.7 0.0 0.0 0.9 0.4 0.6 0.0 0.0 0.3 16.0 0.0 0.0 0.1 0.0 0.1 16.5 0.1 0.0 0.0 0.7 0.0 5.6 1.2 0.0 7.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.5 0.1 0.2 0.3 0.1 0.2 0.0 0.2 0.4 0.2 12.8 12.1 0.0 0.1 0.5 7.7 25.6 14.8 0.3 3.7 3.7 0.6 1.5 4.9 7.3 0.0 0.7 0.4 8.0 0.0 4.9 0.7 15.7 2.9 0.3 0.0 0.0 0.1 2.0 0.2 1.2 8.2 28.9 0.0 0.0 0.0 0.0 2.3 0.0 0.7 2.4 2.0 0.3 5.1 0.1 0.0 5.0 0.0 0.0 5.3 0.1 0.0 0.0 0.1 1.3 0.5 0.4 1.2 4.9 8.9 9.3 1.0 0.3 0.0 0.4 3.0 0.0 0.0 13.7 0.6 0.3 1.0 0.1 7.4 6.5 TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 12.0;breast: 4.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Fibroblasts: 7.5;Hepatic stellate cells: 2.5;Langerhans cells: 2.5;Smooth muscle cells: 10.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.6;NB-4: 3.6;THP-1: 11.1;U-266/70: 2.7;U-937: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" NA NA 34000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" 12.0 0.2 0.0 0.1 0.1 0.0 4.9 0.0 0.1 0.1 0.1 0.3 0.8 0.0 0.0 0.1 0.0 1.7 0.3 0.2 0.0 0.4 1.3 0.4 0.1 0.0 0.1 0.0 0.3 0.8 2.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 3.1 0.4 0.4 0.1 0.4 0.4 0.1 0.1 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 11.1 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 6.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.7 0.0 0.1 7.5 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 10.4 0.4 1.4 0.0 1.8 0.1 0.1 0.0 0.0 0.1 TNR ENSG00000116147 "Tenascin R" Q92752 1 175315194-175743616 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 31.3;retina: 16.2" "Group enriched" "Detected in some" 6 "Horizontal cells: 580.5;Oligodendrocyte precursor cells: 2288.6" "Cancer enriched" "Detected in single" 46 "glioma: 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 1.9;U-937: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022343, HPA027134, HPA027150, HPA029859" Enhanced "Secreted in brain" NA NA 58000 "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022343: , HPA027134: AB_1851983, HPA027150: AB_1851985, HPA029859: AB_10600916" "unprognostic (1.04e-1)" "unprognostic (7.43e-2)" "unprognostic (3.11e-2)" "unprognostic (1.12e-3)" "unprognostic (2.38e-1)" "unprognostic (1.51e-2)" "unprognostic (9.66e-2)" "unprognostic (2.57e-2)" "unprognostic (5.79e-2)" "unprognostic (5.06e-2)" "unprognostic (3.03e-3)" "unprognostic (7.26e-4)" "unprognostic (4.48e-4)" "unprognostic (3.26e-3)" "unprognostic (3.83e-1)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" 0.0 1.4 30.7 0.2 24.3 0.1 0.0 15.2 26.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 31.3 27.7 0.0 0.4 0.5 0.2 23.3 16.4 0.0 0.4 0.0 2.7 0.0 20.3 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.4 0.0 20.8 0.2 0.3 0.4 18.2 0.1 0.1 0.0 0.3 0.0 0.0 30.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.7 24.3 15.2 26.3 31.3 27.7 23.3 16.4 20.3 20.8 18.2 30.5 0.0 0.0 0.0 20.2 2.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 226.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 580.5 179.6 0.0 0.0 0.0 0.3 1.6 0.0 0.1 0.0 3.7 0.0 1.8 0.0 2288.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.8 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TOR2A "FLJ14771, TORP1" ENSG00000160404 "Torsin family 2 member A" "Q5JU69, Q8N2E6" 9 127731524-127735313 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 69.1;Theca cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071229 Approved Uncertain "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA071229: AB_2732175" "unprognostic (1.67e-1)" "unprognostic (9.19e-3)" "unprognostic (1.47e-1)" "unprognostic (1.27e-3)" "unprognostic (3.04e-2)" "unprognostic (6.97e-2)" "unprognostic (2.43e-3)" "unprognostic (4.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.33e-1)" "unprognostic (6.51e-3)" "unprognostic (1.05e-2)" "unprognostic (6.98e-2)" "prognostic favorable (7.51e-4)" "unprognostic (1.72e-1)" "unprognostic (3.27e-1)" "unprognostic (2.82e-2)" 6.8 10.7 9.6 6.8 9.3 26.9 6.7 9.4 13.2 7.9 9.5 12.2 11.2 6.7 3.4 11.4 7.0 4.9 5.4 9.2 9.1 10.2 14.0 8.7 7.7 9.4 9.2 8.2 13.6 3.1 10.0 7.9 8.9 8.1 5.4 2.9 8.7 3.6 3.3 9.5 12.8 2.7 8.6 20.8 11.8 20.4 9.7 8.4 8.7 2.2 4.5 7.1 7.1 9.1 7.4 11.5 9.7 12.2 4.7 4.6 13.0 5.1 6.3 8.0 6.3 7.9 12.6 13.6 7.5 4.4 6.0 23.2 3.0 6.4 2.2 21.1 11.0 5.2 10.6 9.7 7.7 11.0 27.0 7.4 11.8 7.4 3.9 4.0 11.5 16.2 16.2 37.3 4.7 43.4 14.3 34.7 8.7 24.0 9.9 23.4 4.5 30.9 8.3 6.9 21.0 8.3 4.7 16.6 5.3 5.3 37.0 21.4 7.2 5.2 6.0 9.1 6.0 23.4 21.8 5.6 6.4 17.8 5.0 26.5 68.5 96.5 32.8 80.2 26.1 12.1 18.9 32.5 71.6 18.0 14.0 25.2 44.0 26.9 78.3 16.2 32.2 41.5 9.6 9.3 9.4 13.2 9.2 9.1 9.4 9.2 8.9 8.6 9.7 9.1 5.3 3.2 5.1 6.2 12.4 1.5 4.4 16.6 1.2 13.7 8.7 5.8 0.6 15.7 9.6 3.7 0.0 37.9 16.0 26.4 1.9 19.1 69.1 7.0 5.7 8.5 22.8 34.1 5.5 27.4 38.9 10.1 8.2 10.8 5.7 11.7 15.0 7.5 56.9 8.4 4.6 20.4 20.3 33.9 8.3 10.7 11.5 26.2 3.6 2.8 25.2 11.7 30.9 6.0 3.7 15.5 28.7 11.3 21.1 6.0 33.9 8.7 7.7 14.6 0.0 2.5 4.2 30.6 10.9 7.5 1.4 51.9 15.0 114.6 18.3 4.9 TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240379-1242554 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "granulocytes: 5873.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 893 "basophil: 89.3" "Lineage enriched" "Detected in single" 893 "granulocytes: 89.3" "Cell line enriched" "Detected in some" 166 "HMC-1: 3813.2" "CAB016369, CAB022175, HPA049153, HPA049554" Supported "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "CAB016369: AB_628406, CAB022175: , HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favorable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" 96.6 2.9 0.3 23.6 0.5 2.4 47.2 0.3 0.9 53.7 0.9 83.0 71.6 73.3 6.0 64.3 26.6 129.7 14.7 0.4 0.4 13.9 12.2 128.5 21.3 0.4 0.3 3.2 18.9 2.3 3.5 1.2 0.6 65.9 34.6 0.0 60.2 22.5 10.1 122.7 148.7 17.9 0.4 5.9 104.0 8.9 0.4 14.2 4.7 13.0 13.2 113.5 52.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 1.3 3813.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.3 2.1 6.1 0.5 0.4 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.1 1.1 0.0 0.0 2.8 22.9 2.0 89.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.5 0.3 0.9 0.4 0.4 0.4 0.3 0.6 0.4 0.4 0.3 0.0 25.6 135.5 0.0 2.9 18.6 5.1 0.0 1.2 0.0 0.9 0.1 0.3 0.0 8.1 0.0 0.0 0.0 0.2 0.9 0.0 1.2 0.3 0.0 0.0 4.1 0.0 3.8 0.0 0.0 0.2 7.6 0.5 0.0 5873.9 0.0 0.0 0.3 5.2 0.0 0.0 0.0 0.0 0.3 25.6 0.2 0.0 7.7 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 11.7 4.0 0.4 0.1 5.1 0.0 0.0 0.3 3.2 0.0 0.1 0.1 9.9 0.3 440.9 0.0 0.5 5.6 TPSB2 ENSG00000197253 "Tryptase beta 2" P20231 16 1227272-1230184 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 25 "granulocytes: 8966.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 50 "basophil: 5.0" "Lineage enriched" "Detected in single" 50 "granulocytes: 5.0" "Cell line enriched" "Detected in some" 7 "HMC-1: 297.5" "HPA049153, HPA049554" Supported "Secreted to blood" NA NA 16000000 "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" 95.1 2.5 0.3 20.2 0.6 4.3 47.8 0.3 0.9 53.2 1.0 77.8 35.5 71.8 9.8 64.6 30.4 103.9 15.0 0.5 0.5 15.5 12.2 127.8 26.2 0.5 0.4 3.5 18.9 1.5 3.9 1.3 0.5 67.0 19.8 0.0 64.5 13.3 10.0 122.5 146.1 22.0 0.5 5.2 102.1 9.9 0.5 4.9 4.7 10.4 9.9 118.6 53.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.2 0.4 297.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 4.7 0.3 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.7 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.3 0.9 0.5 0.5 0.5 0.4 0.5 0.5 0.5 0.3 0.1 38.5 275.3 0.0 2.8 0.0 4.4 0.0 0.0 0.0 1.5 0.0 1.5 0.0 16.7 0.0 0.0 0.1 0.6 0.7 0.0 2.4 0.6 0.0 0.0 3.2 0.0 18.9 0.0 0.0 0.2 6.0 2.0 0.0 8966.1 0.0 0.0 0.0 3.8 0.0 0.1 0.7 0.0 0.0 0.0 1.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 25.8 5.4 0.7 0.1 3.6 0.0 0.0 0.4 1.1 0.0 0.7 0.0 0.0 0.1 345.1 0.0 1.0 6.1 TREM1 "CD354, TREM-1" ENSG00000124731 "Triggering receptor expressed on myeloid cells 1" Q9NP99 6 41267926-41286682 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 96.0;lung: 65.3;lymphoid tissue: 44.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 26.1;Hofbauer cells: 25.1;Kupffer cells: 35.5;Langerhans cells: 21.5;Late spermatids: 20.6;Macrophages: 104.2;monocytes: 19.9" "Cancer enhanced" "Detected in many" "lung cancer: 9.6" "Region enhanced" "Detected in some" "cerebral cortex: 8.5" "Immune cell enriched" "Detected in many" 7 "neutrophil: 615.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 615.1" "Group enriched" "Detected in some" 4 "SuSa: 6.2;U-87 MG: 24.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005563, HPA053612" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA005563: AB_1858259, HPA053612: " "unprognostic (6.41e-2)" "unprognostic (1.47e-3)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (6.07e-3)" "unprognostic (2.97e-2)" "unprognostic (5.73e-5)" "unprognostic (1.29e-1)" "unprognostic (1.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.24e-3)" "unprognostic (7.65e-2)" "unprognostic (3.18e-7)" "unprognostic (6.32e-3)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (7.26e-2)" 20.4 1.4 0.4 44.1 0.4 96.0 1.2 0.4 8.5 0.8 2.3 0.9 0.4 2.2 0.0 1.5 3.9 9.9 3.8 0.4 0.6 1.1 6.9 65.3 0.4 0.9 0.7 0.5 3.9 1.1 2.4 7.7 1.9 0.7 0.3 0.6 1.2 0.5 0.5 0.2 1.0 8.4 0.6 11.1 0.8 0.3 2.6 3.1 0.7 2.6 1.3 12.6 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 6.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 1.6 0.0 0.1 82.7 2.3 0.0 20.7 0.1 0.6 0.1 0.0 32.8 1.5 0.2 0.0 615.1 0.2 10.1 0.7 0.0 32.5 0.4 0.4 0.4 8.5 0.4 0.6 0.9 0.7 1.9 0.6 2.6 0.9 0.0 6.4 26.1 0.0 1.8 0.4 0.4 5.4 0.0 0.0 0.1 0.1 0.3 2.8 12.4 0.0 0.0 0.4 0.3 0.1 0.0 0.3 12.1 0.3 1.8 3.8 0.0 0.0 0.0 0.2 1.1 2.5 1.1 0.1 6.3 0.0 0.7 0.5 25.1 0.0 0.0 0.0 2.0 35.5 21.5 20.6 0.0 104.2 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.2 0.0 0.3 13.3 0.1 0.0 0.8 2.8 0.0 0.1 0.0 0.1 14.6 2.0 0.0 0.0 0.1 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TREML4 TLT4 ENSG00000188056 "Triggering receptor expressed on myeloid cells like 4" Q6UXN2 6 41228339-41238882 "Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "eosinophil: 4.5;neutrophil: 8.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 6 "HEL: 1.1" "Not detected" "Not detected" HPA065044 Uncertain Approved "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA065044: AB_2685411" "unprognostic (1.49e-1)" "unprognostic (1.51e-1)" "unprognostic (5.58e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (9.50e-3)" "unprognostic (1.18e-4)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (5.26e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.3 0.2 0.7 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.5 0.0 0.4 0.0 0.1 0.0 0.0 0.5 0.9 0.0 0.0 8.1 0.0 0.4 0.7 0.0 0.4 0.0 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRH ENSG00000170893 "Thyrotropin releasing hormone" P20396 3 129974688-129977935 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 68.7;cervix: 26.0;endometrium 1: 18.7;retina: 35.2" "Cell type enriched" "Detected in some" 10 "Muller glia cells: 234.5" "Group enriched" "Detected in some" 5 "breast cancer: 13.3;endometrial cancer: 10.2;glioma: 4.3" "Group enriched" "Detected in many" 6 "hypothalamus: 68.7;medulla oblongata: 59.4;pons: 38.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.0" "Group enriched" "Detected in many" 5 "hypothalamus: 175.6;olfactory bulb: 148.0" "Low region specificity" "Detected in many" HPA035596 Enhanced "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 5: Muller glia cells - Visual perception" "HPA035596: AB_2674695" "unprognostic (1.22e-1)" "unprognostic (8.94e-2)" "unprognostic (5.82e-3)" "unprognostic (5.24e-2)" "unprognostic (2.82e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (4.44e-2)" "unprognostic (3.86e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" 0.2 0.0 4.9 0.1 0.9 3.7 1.9 2.2 0.8 26.0 0.1 0.0 0.1 18.7 0.0 0.0 2.5 0.0 0.5 2.3 68.7 0.5 0.0 0.6 0.0 59.4 9.1 3.8 0.0 0.0 0.2 0.2 38.2 0.1 0.0 35.2 0.5 0.1 0.1 0.4 0.0 0.3 2.8 0.1 0.0 1.2 3.7 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.9 2.2 0.8 2.3 68.7 59.4 9.1 38.2 2.8 3.7 0.7 0.3 0.0 0.0 0.3 0.2 0.8 0.7 0.0 0.0 10.4 1.6 1.4 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 7.1 9.0 0.8 0.7 0.0 0.0 0.2 0.0 0.1 0.2 0.0 22.5 0.0 0.1 0.0 0.0 0.1 5.0 0.3 0.0 0.0 0.0 11.5 2.7 0.0 2.0 0.0 0.0 0.0 234.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9.2 0.0 0.0 0.2 0.7 1.6 0.0 0.1 0.1 0.2 0.1 0.0 4.3 TSHB ENSG00000134200 "Thyroid stimulating hormone subunit beta" P01222 1 115029826-115034302 "Human disease related genes, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2634 "pituitary gland: 1757.6" "Cell type enhanced" "Detected in single" "Late spermatids: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Not detected" "Not detected" "CAB022202, HPA042681" Enhanced "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: Spermatids - Spermatogenesis" "CAB022202: , HPA042681: AB_2732500" "unprognostic (2.14e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" 0.1 0.6 0.3 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.4 0.2 0.0 0.4 0.3 0.0 0.3 0.0 1757.6 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.2 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.4 0.3 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 237.3" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 506.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 168.0;ASC diff: 282.5;OE19: 188.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" NA NA 6200000 "Cluster 6: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nuclear bodies" "HPA008164: AB_1853327" "unprognostic (1.07e-2)" "unprognostic (2.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (3.66e-4)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (4.81e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (2.87e-4)" "prognostic favorable (1.66e-4)" "prognostic unfavorable (2.80e-8)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (6.71e-2)" "unprognostic (3.88e-2)" 96.5 12.1 4.2 8.3 4.5 2.1 80.4 6.5 5.8 147.1 27.8 23.5 37.1 46.4 20.6 62.8 67.7 14.9 34.8 6.5 2.7 41.5 237.3 15.0 2.4 4.4 3.1 47.0 16.8 6.4 14.8 30.3 5.0 44.0 14.4 4.1 33.9 24.6 9.5 60.0 32.3 41.1 1.9 6.9 28.2 9.1 3.9 4.7 37.6 5.7 5.6 41.6 99.6 4.4 3.7 168.0 19.1 18.4 282.5 36.1 34.6 5.9 32.2 12.6 12.0 22.2 48.0 0.3 32.7 21.1 53.7 68.6 10.9 42.7 3.9 35.7 5.9 8.3 43.5 63.1 53.6 3.0 11.9 37.3 46.0 22.5 18.2 24.0 15.7 6.4 19.9 1.4 11.7 81.9 0.5 6.5 24.5 188.9 7.4 5.9 18.3 28.7 29.7 29.7 16.8 28.5 32.7 25.7 15.4 15.8 34.5 2.7 4.9 35.4 28.2 86.8 14.2 1.1 0.6 1.4 16.6 8.9 6.4 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 4.2 4.5 6.5 5.8 6.5 2.7 4.4 3.1 5.0 1.9 3.9 4.4 6.2 0.0 0.5 1.0 0.5 17.3 12.1 25.8 27.9 3.5 13.6 13.2 3.2 11.5 12.1 1.8 0.0 50.0 0.1 33.2 0.0 6.7 0.2 8.1 35.6 5.8 7.8 13.5 0.5 21.7 71.8 33.0 14.8 10.6 1.3 38.7 9.7 506.3 9.9 0.0 0.1 12.4 26.4 9.1 6.4 2.0 37.3 0.8 5.4 1.9 1.6 9.2 0.0 0.0 0.0 21.3 21.2 45.1 0.1 14.6 28.6 21.9 3.0 0.6 0.0 1.0 11.3 0.4 2.0 22.3 22.6 43.8 1.6 8.6 13.8 20.1 TSLP ENSG00000145777 "Thymic stromal lymphopoietin" Q969D9 5 111070062-111078026 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 11.5;urinary bladder: 12.0" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 108.1;Basal squamous epithelial cells: 338.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 15.0;HHSteC: 17.1;hTCEpi: 10.3;hTEC/SVTERT24-B: 18.9;hTERT-HME1: 12.5;hTERT-RPE1: 38.6;U-87 MG: 14.1" "Not detected" "Not detected" HPA056350 Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 38400 "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "HPA056350: " "unprognostic (6.47e-4)" "unprognostic (3.26e-1)" "unprognostic (6.57e-2)" "unprognostic (1.93e-1)" "unprognostic (5.03e-2)" "unprognostic (7.72e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-2)" "unprognostic (5.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-1)" "unprognostic (1.88e-1)" "unprognostic (5.04e-2)" "unprognostic (1.95e-1)" "unprognostic (2.76e-1)" "unprognostic (1.74e-3)" 1.6 0.7 0.3 1.3 0.3 0.0 1.5 0.3 0.5 1.4 0.2 1.1 0.7 0.8 0.3 3.8 0.6 8.8 4.3 0.3 0.3 1.2 11.5 1.9 0.4 0.4 0.3 0.3 0.3 0.4 0.4 0.1 0.4 6.2 0.9 0.0 1.2 4.0 1.4 0.8 1.0 0.6 0.3 0.4 1.2 4.8 1.1 0.2 2.7 1.4 0.5 12.0 1.9 0.4 0.0 0.0 0.0 1.8 2.3 15.0 0.0 0.0 2.3 0.4 2.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.5 0.8 0.0 2.4 2.8 0.1 0.0 17.1 0.5 0.0 0.3 10.3 18.9 12.5 38.6 0.0 6.6 0.3 0.0 3.2 0.0 2.5 0.0 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.0 1.2 0.0 1.1 0.0 0.0 0.9 0.0 0.0 4.1 0.0 0.0 14.1 0.3 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.3 0.3 0.4 0.3 0.4 0.3 1.1 0.4 6.2 0.0 3.1 0.3 0.1 55.8 26.6 108.1 338.6 0.0 6.5 8.0 7.4 0.0 35.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 38.5 0.1 0.9 10.5 0.0 0.0 0.0 0.0 0.1 10.0 0.0 0.1 0.0 0.9 7.9 9.4 0.2 0.0 0.0 0.0 24.4 1.2 5.0 26.3 0.6 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 24.7 0.2 1.6 3.5 0.0 0.0 6.9 3.8 0.4 0.9 38.0 25.1 0.0 0.8 1.9 0.1 3.1 TSPEAR "C21orf29, DFNB98, MGC11251, TSP-EAR" ENSG00000175894 "Thrombospondin type laminin G domain and EAR repeats" Q8WU66 21 44497893-44711572 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.3;Early spermatids: 3.3;Excitatory neurons: 1.1;Oligodendrocytes: 1.0" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 1.7;U-2 OS: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "CAB034203, CAB034204, HPA052995" Uncertain "Secreted in other tissues" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "CAB034203: AB_1567654, CAB034204: AB_1567655, HPA052995: AB_2682008" "unprognostic (8.61e-3)" "unprognostic (2.45e-1)" "unprognostic (1.86e-4)" "unprognostic (7.87e-3)" "unprognostic (4.08e-2)" "unprognostic (1.00e-3)" "unprognostic (7.92e-3)" "unprognostic (1.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (3.86e-4)" "unprognostic (2.13e-2)" "unprognostic (4.80e-7)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.0 1.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 TTC9B FLJ30373 ENSG00000174521 "Tetratricopeptide repeat domain 9B" Q8N6N2 19 40216058-40218399 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "brain: 110.8;choroid plexus: 32.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.1;Excitatory neurons: 39.3;Horizontal cells: 18.5;Inhibitory neurons: 19.7;Oligodendrocyte precursor cells: 27.2" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "SCLC-21H: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042496 Approved Approved Nucleoplasm,Vesicles,Mitochondria "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" Vesicles "HPA042496: AB_10795506" "unprognostic (2.31e-1)" "unprognostic (1.39e-4)" "unprognostic (5.09e-2)" "unprognostic (5.24e-2)" "unprognostic (8.47e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (7.95e-2)" "unprognostic (2.78e-1)" "unprognostic (1.54e-2)" "unprognostic (3.69e-1)" "unprognostic (8.75e-6)" "unprognostic (1.39e-1)" "unprognostic (8.23e-2)" "unprognostic (1.95e-1)" "unprognostic (5.24e-2)" 0.0 0.6 73.9 0.3 74.7 0.0 0.0 49.7 110.8 0.0 32.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 84.2 60.6 0.2 0.0 0.0 0.0 45.1 46.3 0.0 0.0 0.0 0.9 0.0 46.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.1 43.0 0.0 0.2 0.3 60.4 0.0 0.0 0.0 0.0 0.0 0.1 69.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 26.8 1.4 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 73.9 74.7 49.7 110.8 84.2 60.6 45.1 46.3 46.4 43.0 60.4 69.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.1 0.0 39.1 0.2 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.8 0.2 0.2 1.8 0.0 39.3 0.5 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 18.5 19.7 0.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 4.7 0.0 1.7 0.0 27.2 5.0 0.1 1.2 0.7 0.0 0.1 0.0 0.0 1.2 8.4 0.0 0.0 0.1 7.0 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 TTR "CTS, CTS1, HsT2651, PALB" ENSG00000118271 Transthyretin P02766 18 31557009-31598833 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Transport "Hormone, Thyroid hormone" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "choroid plexus: 142023.1" "Cell type enriched" "Detected in many" 30 "Hepatocytes: 23659.3" "Group enriched" "Detected in many" 28 "liver cancer: 928.2;pancreatic cancer: 666.0" "Group enriched" "Detected in all" 7 "cerebellum: 621.7;hippocampal formation: 1730.9;thalamus: 688.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 160.1;EFO-21: 39.6;Hep G2: 249.0;U-2 OS: 57.0" "Group enriched" "Detected in all" 5 "basal ganglia: 1538.3;hippocampal formation: 4891.0;pons and medulla: 5758.5;thalamus: 3400.4" "Region enhanced" "Detected in all" "medulla oblongata: 1381.8" "CAB002517, HPA002550, CAB062567, CAB073406" Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 345000000000 99000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB002517: AB_563965, CAB062567: AB_2665620, CAB073406: , HPA002550: AB_1080419" "unprognostic (6.79e-3)" "unprognostic (3.38e-2)" "unprognostic (4.10e-1)" "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (8.15e-2)" "unprognostic (3.74e-2)" "unprognostic (9.66e-3)" "unprognostic (8.72e-2)" "unprognostic (1.23e-2)" "unprognostic (8.35e-3)" "unprognostic (5.26e-1)" "unprognostic (3.52e-2)" 4.2 0.6 148.5 0.5 56.7 9.6 0.4 621.7 83.7 2.0 142023.1 6.0 14.9 1.3 0.9 2.2 0.8 51.2 2.9 1730.9 37.3 18.4 21288.1 0.8 2.4 106.5 86.0 1.1 1785.1 186.8 6.0 2.7 27.1 1.6 4.5 80.1 1.8 0.4 1.1 15.6 6.8 0.3 12.3 3.8 49.8 2.3 688.2 1.1 1.3 0.0 0.1 2.3 0.6 133.9 1.6 0.4 0.6 0.5 0.8 0.1 1.0 0.8 0.3 0.0 0.0 160.1 0.0 2.9 39.6 0.5 0.6 0.4 0.0 0.3 0.0 5.9 0.8 5.2 1.8 249.0 0.4 11.2 1.0 0.1 0.1 0.1 0.0 0.7 0.0 0.3 2.8 0.4 0.0 0.5 0.4 0.7 0.6 4.5 0.3 0.3 7.4 0.2 0.3 1.6 0.9 1.1 5.8 0.0 0.2 1.7 0.6 0.2 1.7 2.4 57.0 0.5 4.3 1.0 2.6 17.6 0.7 4.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.1 0.0 0.1 0.0 0.0 148.5 56.7 621.7 83.7 1730.9 37.3 106.5 86.0 27.1 12.3 688.2 133.9 0.0 0.0 0.0 0.0 15.1 0.5 0.0 0.0 0.0 144.8 0.0 0.0 1.8 779.2 0.0 5.5 162.6 0.3 0.0 1.5 5.9 3.1 6.8 0.5 0.5 14.1 356.2 192.5 0.0 2.0 3.6 0.7 13.3 0.0 0.0 0.2 192.4 23659.3 2.4 26.9 0.1 19.6 0.0 313.7 0.0 8.7 0.3 1.2 0.0 0.0 0.0 24.9 0.0 0.0 0.0 130.5 5.2 0.0 0.0 0.2 1.3 26.9 0.0 56.0 0.0 0.0 0.3 3.3 1.1 0.0 0.1 4.0 10.9 0.0 1.7 0.0 TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 111.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.2;Glandular and luminal cells: 76.8;Suprabasal keratinocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" 5.6 6.8 4.7 2.8 4.2 6.7 10.1 5.0 5.3 25.4 3.4 11.6 7.5 5.3 6.3 48.1 5.1 5.9 4.9 3.8 5.9 14.1 7.0 8.4 0.9 4.0 4.0 7.4 17.2 11.4 7.2 13.3 5.2 9.6 13.0 2.1 18.3 9.2 2.5 111.5 10.8 6.2 3.3 1.5 12.8 5.4 6.2 2.2 5.7 2.7 6.2 12.4 26.8 3.5 40.7 13.7 10.0 11.5 2.3 1.9 63.1 10.7 9.5 41.3 39.6 43.6 31.5 3.5 64.6 12.5 19.5 46.4 17.6 16.2 30.1 27.0 8.7 2.2 23.0 6.7 32.2 0.8 4.7 6.5 18.9 32.5 71.6 24.5 3.4 5.0 3.6 26.8 12.8 16.8 2.0 0.5 11.7 29.6 11.4 0.1 28.1 14.2 34.7 61.8 19.5 8.0 68.2 45.8 8.0 29.4 36.5 2.1 8.6 7.4 51.7 46.2 71.7 6.6 13.7 0.5 6.3 0.9 4.7 5.2 0.6 0.7 0.3 0.1 0.7 0.6 1.0 0.5 0.9 0.2 0.8 0.3 2.5 0.1 0.3 0.1 3.5 0.5 4.7 4.2 5.0 5.3 3.8 5.9 4.0 4.0 5.2 3.3 6.2 3.5 2.1 25.6 2.0 1.6 3.8 69.2 35.2 14.7 35.9 2.5 28.8 20.2 9.8 8.6 19.0 14.7 0.0 28.1 6.6 59.5 13.7 18.2 2.7 43.2 8.9 2.7 32.2 2.7 4.4 15.2 13.9 7.0 46.9 76.8 4.5 9.0 1.1 10.5 4.0 0.0 9.3 39.1 20.3 0.0 12.7 3.2 2.5 6.5 8.8 1.0 2.0 2.1 0.0 8.5 1.8 47.4 34.6 5.3 7.7 21.7 15.4 11.2 15.9 0.5 6.6 4.1 5.5 0.6 3.5 39.6 66.5 56.8 5.8 10.9 35.7 35.6 TULP2 "CT65, TUBL2" ENSG00000104804 "TUB like protein 2" O00295 19 48880967-48898744 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 37.6" "Group enriched" "Detected in some" 16 "Early spermatids: 281.1;Late spermatids: 233.0" "Cancer enriched" "Detected in single" 8 "testis cancer: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 3.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 3.0" "Cell line enhanced" "Detected in some" "BEWO: 2.6;U-266/70: 3.0;U-266/84: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075828 Approved Cytosol "Secreted in male reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA075828: " "unprognostic (9.97e-2)" "unprognostic (5.55e-3)" "unprognostic (1.15e-1)" "unprognostic (9.39e-2)" "unprognostic (1.69e-4)" "unprognostic (6.79e-4)" "unprognostic (1.07e-2)" "unprognostic (2.57e-1)" "unprognostic (5.94e-3)" "unprognostic (1.08e-2)" "unprognostic (9.82e-2)" "unprognostic (1.33e-1)" "unprognostic (4.59e-4)" "unprognostic (6.37e-2)" "unprognostic (1.63e-1)" "unprognostic (1.08e-1)" "unprognostic (1.97e-1)" 0.2 0.5 1.9 0.1 2.3 5.2 0.5 3.5 8.4 0.3 1.0 0.3 0.0 1.0 0.1 0.8 0.8 0.8 0.5 2.3 1.9 0.2 0.1 0.5 0.2 1.6 1.4 1.4 0.1 0.1 0.1 0.1 2.0 0.7 0.2 0.5 0.1 0.2 0.5 0.1 0.5 0.4 1.4 1.4 0.4 37.6 2.1 0.1 0.3 0.1 0.3 0.3 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.7 0.9 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.4 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.0 3.4 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.0 0.0 0.0 1.9 2.3 3.5 8.4 2.3 1.9 1.6 1.4 2.0 1.4 2.1 1.7 0.2 0.0 0.5 0.3 0.8 0.3 0.1 0.0 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 281.1 0.8 2.7 1.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 2.2 2.5 0.1 0.0 0.2 0.2 0.0 0.6 0.2 0.0 0.3 0.7 233.0 4.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 6.4 1.4 15.4 1.4 0.4 0.4 0.0 0.6 0.1 0.0 0.0 TWSG1 TSG ENSG00000128791 "Twisted gastrulation BMP signaling modulator 1" Q9GZX9 18 9334767-9402420 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.2;Peritubular cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014898 Uncertain Supported Centrosome,Cytosol "Secreted - unknown location" No No 3500000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Centrosome, Cytosol" "HPA014898: AB_1858467" "unprognostic (2.55e-1)" "unprognostic (3.17e-2)" "unprognostic (7.31e-2)" "unprognostic (8.95e-3)" "unprognostic (2.92e-3)" "unprognostic (1.83e-1)" "unprognostic (8.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.33e-2)" "unprognostic (1.05e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" 23.7 19.5 7.7 16.7 9.6 8.2 17.5 9.2 12.2 40.6 12.7 22.1 11.1 51.3 45.8 26.1 30.5 36.3 18.6 7.4 9.2 36.3 10.0 19.7 11.8 10.5 9.4 32.3 9.7 33.2 9.8 24.8 10.4 43.0 22.4 5.7 11.1 64.6 5.7 12.9 12.5 80.1 9.7 13.6 14.9 11.8 8.9 7.0 34.9 16.5 14.9 34.7 16.2 11.0 57.3 19.9 57.6 28.6 111.2 99.7 26.6 107.2 132.4 57.6 81.9 21.2 73.5 8.2 52.7 142.5 37.4 19.5 57.1 42.4 105.3 22.0 15.4 14.7 15.9 10.8 98.7 10.8 29.4 102.0 34.1 48.3 23.3 78.7 90.8 7.8 22.7 14.6 149.2 17.0 11.9 13.2 18.9 33.6 16.1 20.7 58.7 5.0 65.7 75.2 7.4 20.0 83.3 23.1 22.9 23.9 26.1 25.0 75.6 104.9 52.4 99.5 67.5 21.2 20.1 15.1 64.5 14.9 37.9 8.3 2.7 4.0 4.3 1.5 2.8 2.1 2.0 4.5 5.5 1.6 2.3 4.8 1.2 2.9 0.5 5.3 1.0 2.1 7.7 9.6 9.2 12.2 7.4 9.2 10.5 9.4 10.4 9.7 8.9 11.0 9.0 25.6 18.4 13.1 8.1 39.6 21.3 18.5 51.2 4.8 18.5 11.6 7.8 10.0 21.0 75.4 0.0 6.3 12.1 12.1 1.9 9.1 141.2 13.3 38.6 18.1 6.0 9.9 28.0 7.6 18.3 61.9 10.2 23.4 6.3 31.6 17.2 7.5 16.0 3.3 31.0 8.2 57.0 9.4 30.1 30.7 37.6 12.2 23.2 17.8 15.3 16.1 7.2 29.1 31.6 9.2 10.7 95.2 17.8 46.3 1.3 12.6 12.4 5.0 72.3 28.9 56.6 24.6 9.6 26.6 26.9 4.7 10.1 20.4 12.2 27.1 TXNDC16 KIAA1344 ENSG00000087301 "Thioredoxin domain containing 16" Q9P2K2 14 52430596-52552522 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 26.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 69.8;Glandular and luminal cells: 124.9;Inhibitory neurons: 88.8" "Cancer enhanced" "Detected in all" "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002543 Approved Approved Mitochondria "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA002543: AB_1079199" "unprognostic (1.37e-1)" "unprognostic (7.79e-3)" "unprognostic (5.95e-3)" "unprognostic (2.36e-1)" "unprognostic (5.95e-3)" "unprognostic (9.73e-2)" "unprognostic (2.50e-1)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-2)" "unprognostic (1.21e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (3.55e-3)" "unprognostic (2.04e-1)" 6.2 4.0 4.6 3.5 4.6 5.1 6.9 10.1 6.0 9.3 0.6 5.8 4.1 6.9 14.6 3.7 4.1 5.2 3.7 4.9 4.3 5.0 7.4 4.4 4.5 3.9 4.0 10.3 6.4 7.0 3.8 5.8 4.3 26.7 5.9 9.1 4.0 13.0 2.0 4.6 4.8 4.3 4.0 10.2 6.3 7.1 4.1 5.9 4.0 4.0 3.9 3.4 3.8 6.7 8.3 0.8 8.9 5.0 6.5 4.7 7.0 2.7 3.6 4.5 8.7 3.0 6.6 13.5 8.9 2.2 2.8 7.7 10.3 3.7 6.9 5.7 13.5 6.2 6.2 2.8 4.7 7.4 2.9 8.8 3.4 5.8 4.2 4.0 5.1 5.8 8.0 20.4 3.9 4.0 9.3 5.1 9.9 5.5 4.9 18.4 16.9 12.4 5.7 8.4 29.0 10.0 13.2 13.5 3.9 7.5 8.6 5.4 2.7 6.0 3.0 6.9 4.6 5.6 8.0 13.5 1.7 7.7 3.5 1.3 3.0 1.2 1.3 2.4 1.3 0.5 1.3 0.9 2.6 0.3 0.6 0.6 1.7 0.6 2.9 1.0 2.4 1.0 4.6 4.6 10.1 6.0 4.9 4.3 3.9 4.0 4.3 4.0 4.1 6.7 9.1 9.6 6.4 23.2 6.1 6.6 6.0 2.5 9.6 42.3 26.6 19.0 10.1 8.6 5.0 7.3 8.4 2.3 15.1 8.8 1.9 5.2 4.0 69.8 9.6 7.4 18.5 21.8 61.0 3.9 1.6 7.2 13.3 124.9 2.5 13.9 15.4 14.1 3.3 10.1 88.8 17.9 0.0 18.8 8.6 4.2 27.7 13.0 1.8 24.4 5.9 7.3 7.2 45.8 51.5 1.3 8.5 52.3 11.3 19.0 5.9 2.8 4.4 44.8 0.0 11.1 11.2 12.0 9.5 8.1 8.4 1.1 7.7 5.7 10.9 4.5 UCMA "C10orf49, GRP" ENSG00000165623 "Upper zone of growth plate and cartilage matrix associated" Q8WVF2 10 13221766-13234374 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;ovary: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;basal ganglia: 2.2;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046718 Uncertain "Secreted to extracellular matrix" NA NA 20000 "Cluster 10: Brain - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "HPA046718: AB_2679771" "unprognostic (4.25e-1)" 0.0 0.0 1.2 0.0 2.2 0.0 0.0 0.2 1.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 1.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.2 0.2 1.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 UCN "UI, UROC" ENSG00000163794 Urocortin P55089 2 27307400-27308445 "Predicted secreted proteins" Hearing Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.2" "Cell type enhanced" "Detected in many" "Astrocytes: 7.8;Excitatory neurons: 6.5;Inhibitory neurons: 5.5;Oligodendrocytes: 6.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 19.4" "Low region specificity" "Detected in many" CAB010911 Approved Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 133000 "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB010911: AB_261834" "unprognostic (7.35e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.42e-2)" "unprognostic (5.08e-2)" "unprognostic (7.72e-2)" "unprognostic (5.69e-3)" "unprognostic (2.66e-1)" "unprognostic (2.48e-1)" "unprognostic (1.15e-1)" "unprognostic (3.80e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.84e-7)" "unprognostic (4.84e-2)" "unprognostic (3.87e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" 1.5 5.1 8.6 0.6 8.2 1.1 1.5 8.4 13.5 3.3 4.2 2.4 0.3 2.4 0.5 0.9 3.0 0.8 4.2 8.0 7.3 2.0 5.9 1.9 0.7 9.7 18.2 2.9 2.3 0.0 4.3 1.0 14.9 3.0 0.0 0.9 0.9 0.3 4.8 1.3 1.9 0.4 7.1 2.9 1.3 2.8 8.4 0.6 1.7 0.4 0.2 2.8 1.7 10.1 1.2 2.7 0.4 0.7 1.2 1.0 5.1 0.4 1.0 0.4 0.4 0.2 2.1 1.1 0.6 0.4 1.2 0.4 0.4 0.3 0.0 3.4 4.4 2.4 2.0 2.2 2.9 0.2 2.6 1.5 2.0 0.2 2.4 2.6 0.0 2.0 2.4 1.9 0.1 2.0 1.3 7.2 4.4 0.1 2.8 3.5 2.3 1.5 0.1 0.5 0.7 2.3 1.1 0.1 6.4 0.3 1.1 3.2 0.2 0.8 4.8 1.4 1.9 19.4 2.3 0.7 3.7 5.7 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 8.6 8.2 8.4 13.5 8.0 7.3 9.7 18.2 14.9 7.1 8.4 10.1 0.8 0.0 0.5 7.8 1.1 0.5 0.3 0.3 0.0 2.3 1.8 1.0 0.4 4.3 0.2 0.0 0.0 0.6 3.2 0.5 0.0 0.7 0.6 0.5 0.9 0.8 0.0 2.7 6.5 3.8 0.6 0.7 0.0 0.5 0.0 1.2 1.1 1.1 0.7 1.7 5.5 0.3 2.0 1.3 2.4 0.4 1.5 0.9 0.0 3.7 0.9 1.8 0.0 2.5 6.0 0.6 1.1 0.7 0.1 0.7 1.1 0.5 0.5 3.5 0.0 1.5 1.2 1.1 0.6 0.0 0.0 0.8 0.8 0.4 0.5 0.1 UCN2 "SRP, UCN-II, UCNI, URP" ENSG00000145040 "Urocortin 2" Q96RP3 3 48561718-48563781 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 13.1;vagina: 4.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.9;Basal respiratory cells: 1.4" "Cancer enriched" "Detected in many" 5 "melanoma: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 18.8;hTCEpi: 27.3;hTEC/SVTERT24-B: 21.5;SiHa: 19.1;U-251 MG: 20.7;WM-115: 55.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA066841 Uncertain Approved Vesicles "Secreted to blood" NA NA 98600 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA066841: AB_2685735" "unprognostic (7.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.80e-2)" "unprognostic (1.96e-2)" "unprognostic (2.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.92e-3)" "unprognostic (2.02e-3)" "unprognostic (1.62e-1)" "unprognostic (2.93e-3)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (3.34e-14)" "unprognostic (4.39e-2)" "unprognostic (2.75e-1)" "unprognostic (1.36e-1)" "unprognostic (2.88e-2)" 0.1 0.0 0.2 0.3 0.1 0.1 0.4 0.3 0.4 2.3 0.1 0.2 0.1 1.2 0.7 3.4 0.2 0.4 0.3 0.2 0.4 1.4 0.0 0.2 0.0 0.3 0.3 0.2 0.0 0.0 0.3 0.2 0.3 3.1 0.0 0.0 1.6 0.4 0.3 13.1 0.2 0.2 0.2 0.7 0.2 1.4 0.3 0.0 0.0 0.0 0.1 0.5 4.5 0.2 0.0 3.1 0.5 0.1 1.8 1.1 2.6 9.7 12.1 5.9 4.4 0.0 0.0 0.0 0.4 2.3 7.0 1.9 0.0 11.6 3.2 9.2 0.2 0.2 18.8 1.5 2.0 0.0 0.5 1.3 27.3 21.5 4.3 4.1 0.0 0.2 0.0 0.2 0.9 0.0 0.0 1.8 0.8 0.0 0.2 0.2 0.3 0.0 1.8 0.0 0.0 0.0 19.1 0.0 14.5 1.7 0.3 0.4 0.0 2.6 1.8 0.3 20.7 0.1 0.3 0.0 8.8 0.1 55.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.2 0.4 0.3 0.3 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 UCN3 "SPC, UCNIII" ENSG00000178473 "Urocortin 3" Q969E3 10 5364966-5374692 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.8;pancreas: 5.8;stomach 1: 3.4" "Cell type enriched" "Detected in some" 29 "Enteroendocrine cells: 242.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.4" "Region enhanced" "Detected in some" "medulla oblongata: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SCLC-21H: 1.2" "Region enhanced" "Detected in some" "hypothalamus: 5.1" HPA038281 Uncertain "Secreted to blood" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA038281: AB_10672408" "unprognostic (2.00e-2)" "unprognostic (2.31e-1)" "unprognostic (1.60e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-3)" "unprognostic (8.42e-2)" "unprognostic (3.55e-2)" "unprognostic (2.91e-2)" 0.0 0.8 1.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 2.3 8.8 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.8 0.7 0.0 0.6 0.0 1.9 0.5 0.0 5.8 0.0 2.7 0.1 0.1 0.3 2.3 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.1 0.0 0.8 1.9 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.1 242.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.3 0.6 2.9 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.2 ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 28.9;Basal respiratory cells: 17.9;dendritic cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "SiHa: 66.7;U-2197: 47.4" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" 1.5 0.7 1.3 0.6 1.6 1.8 0.7 1.6 2.6 0.9 0.7 0.2 0.2 0.1 0.1 6.1 0.2 0.5 2.0 3.0 1.0 2.1 0.5 3.4 0.3 1.8 1.2 0.0 0.4 0.6 0.5 1.6 1.8 0.2 0.1 0.2 0.7 0.1 0.3 0.5 0.2 0.7 0.8 0.2 0.3 1.5 1.1 0.7 1.2 0.7 0.8 1.4 1.6 1.7 19.9 1.8 0.5 6.1 1.1 5.6 3.3 20.1 11.8 20.6 16.8 7.4 11.0 0.0 29.9 23.0 29.6 13.9 7.6 18.4 11.8 9.1 3.9 1.1 2.8 0.0 7.1 0.0 1.5 2.7 13.9 18.3 8.0 16.7 11.9 16.6 2.5 0.0 15.4 13.9 1.8 0.0 0.0 3.6 10.2 3.0 4.5 0.0 29.0 5.7 0.6 0.0 66.7 1.4 1.9 3.2 1.8 8.5 18.8 13.5 17.1 47.4 23.5 0.0 0.1 0.9 19.2 10.7 9.9 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.8 1.5 0.0 0.0 0.3 1.8 0.0 0.4 0.0 0.0 1.7 0.5 1.3 1.6 1.6 2.6 3.0 1.0 1.8 1.2 1.8 0.8 1.1 1.7 28.9 0.0 1.3 0.0 1.2 3.7 6.5 17.9 7.4 0.0 1.3 4.4 0.3 0.0 9.4 1.8 0.0 0.0 12.1 0.5 0.0 7.5 7.0 0.3 0.5 9.1 0.0 0.0 3.0 8.8 0.5 3.0 1.1 0.2 0.0 0.1 7.1 0.2 2.2 0.0 0.7 0.3 2.0 0.8 2.1 8.0 0.0 3.1 1.8 0.0 0.0 0.4 4.1 0.5 0.3 4.5 0.0 0.0 1.4 1.4 0.0 0.1 1.4 0.0 0.0 1.0 4.2 3.1 7.0 11.8 2.8 0.0 11.0 0.6 0.4 5.2 UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 693 "kidney: 2277.8" "Group enriched" "Detected in some" 146 "Collecting duct cells: 248.3;Distal tubular cells: 950.9" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" NA NA 55000000 66000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2277.8 0.8 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 248.3 0.0 0.0 0.0 0.0 950.9 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UTS2 "PRO1068, U-II, UCN2, UII" ENSG00000049247 "Urotensin 2" O95399 1 7843083-7853512 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 43.0" "Cell type enhanced" "Detected in many" "dendritic cells: 15.3;granulocytes: 41.2;monocytes: 17.9;NK-cells: 88.6;T-cells: 18.2" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 5 "medulla oblongata: 43.0;pons: 27.0;white matter: 25.2" "Immune cell enriched" "Detected in many" 5 "T-reg: 45.2" "Lineage enriched" "Detected in many" 5 "T-cells: 45.2" "Cell line enhanced" "Detected in some" "CACO-2: 22.6;HEL: 7.1;HMC-1: 5.7;THP-1: 26.2" "Region enriched" "Detected in single" 19 "pons and medulla: 6.1" "Region enriched" "Detected in some" 12 "spinal cord: 79.7" HPA017000 Uncertain "Secreted to blood" NA NA 2590000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA017000: AB_1858656" "unprognostic (2.10e-3)" "unprognostic (1.35e-1)" "unprognostic (3.89e-3)" "unprognostic (1.33e-3)" "unprognostic (2.32e-5)" "unprognostic (1.09e-4)" "unprognostic (4.95e-2)" "unprognostic (6.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-5)" "unprognostic (1.75e-1)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (3.30e-3)" 0.5 3.7 0.1 0.5 0.1 2.9 0.1 1.5 0.5 0.3 0.0 0.7 0.6 0.1 0.0 0.1 0.4 0.5 0.0 0.2 4.6 0.3 0.1 0.5 1.8 43.0 6.2 0.3 0.0 0.0 0.0 0.0 27.0 1.4 1.2 0.9 0.0 0.0 0.3 0.3 0.5 1.2 4.0 1.1 0.2 0.0 0.9 0.9 0.1 0.0 0.3 0.2 0.1 25.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.1 0.0 0.2 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.5 0.1 0.6 5.0 0.0 6.7 0.0 4.4 4.5 0.8 0.0 0.4 1.3 0.1 6.1 0.0 0.0 45.2 1.7 0.1 0.1 1.5 0.5 0.2 4.6 43.0 6.2 27.0 4.0 0.9 25.2 0.1 0.0 1.9 0.0 5.1 1.5 0.1 0.1 1.8 3.2 0.0 0.0 0.1 0.0 0.7 1.8 0.0 0.0 15.3 2.7 0.0 0.0 0.0 0.0 0.1 0.3 1.2 1.7 0.4 0.0 0.0 0.6 1.1 0.1 41.2 0.0 0.0 0.0 0.1 5.0 0.5 3.7 0.0 0.0 1.3 0.0 0.0 5.5 0.0 1.0 17.9 0.8 88.6 0.5 0.2 0.1 4.7 0.0 4.3 1.2 3.0 0.6 0.0 1.2 0.0 0.2 0.3 0.0 0.0 0.8 0.4 0.1 18.2 0.0 8.0 0.0 UTS2B "U2B, URP, UTS2D" ENSG00000188958 "Urotensin 2B" Q765I0 3 191267168-191330536 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 14.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;B-cells: 2.6;Early spermatids: 8.3;Late spermatids: 2.3;Oligodendrocyte precursor cells: 3.0;Spermatocytes: 2.6;Spermatogonia: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 4 "memory B-cell: 2.8;naive B-cell: 1.8" "Lineage enriched" "Detected in single" 5 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "PC-3: 3.3" "Region enriched" "Detected in some" 9 "pons and medulla: 11.3" "Region enriched" "Detected in single" 46 "spinal cord: 6.0" HPA026992 Uncertain "Secreted - unknown location" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA026992: AB_1858703" "unprognostic (1.73e-2)" "unprognostic (4.38e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.92e-1)" "unprognostic (2.17e-2)" "unprognostic (2.77e-2)" "unprognostic (2.14e-2)" "unprognostic (3.09e-1)" "unprognostic (2.63e-2)" "unprognostic (3.39e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (7.58e-2)" "unprognostic (2.08e-1)" "unprognostic (1.29e-1)" "unprognostic (3.10e-2)" 1.0 1.2 0.8 0.8 0.5 0.5 1.2 4.1 1.4 0.2 0.0 0.5 5.3 0.7 0.5 0.7 1.0 1.2 0.7 0.7 0.5 0.6 3.2 0.5 1.0 0.7 0.4 1.0 0.5 0.2 0.0 0.4 1.1 0.6 0.4 14.9 0.6 0.2 0.5 1.1 3.2 0.5 0.1 0.6 1.6 2.3 0.6 0.1 0.5 0.0 0.3 0.4 0.1 0.9 0.4 1.0 1.3 0.6 0.3 1.6 0.4 1.0 0.5 0.3 0.2 0.7 0.5 0.7 0.5 0.4 2.6 0.5 0.4 0.0 1.6 0.6 0.5 0.6 1.4 2.9 0.3 0.8 0.4 0.6 0.2 0.2 0.3 0.9 0.3 0.6 0.4 0.6 0.5 0.6 0.2 0.5 0.7 1.3 3.3 0.9 1.5 0.2 0.2 1.6 0.7 0.5 0.6 0.7 0.4 0.5 0.5 0.5 1.4 0.7 0.4 1.3 0.4 1.1 0.6 0.6 0.9 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.5 4.1 1.4 0.7 0.5 0.7 0.4 1.1 0.1 0.6 0.9 0.2 3.2 1.1 0.7 2.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 8.3 1.4 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.1 0.0 0.7 1.6 0.0 0.2 0.1 1.5 0.0 0.0 0.1 0.2 2.6 2.1 0.0 0.3 0.3 0.0 0.1 0.0 0.1 VASH1 KIAA1036 ENSG00000071246 "Vasohibin 1" Q7L8A9 14 76761468-76783015 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 67.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 139.7;Early spermatids: 72.8;Late spermatids: 95.3;Microglial cells: 53.4;Rod photoreceptor cells: 98.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 46.1;HEL: 35.1;HUVEC TERT2: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000653 Uncertain "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA000653: AB_1080551" "unprognostic (1.47e-1)" "unprognostic (9.13e-2)" "unprognostic (2.56e-2)" "unprognostic (7.29e-2)" "unprognostic (1.93e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-3)" "unprognostic (1.62e-1)" "unprognostic (9.23e-2)" "unprognostic (6.94e-2)" "prognostic favorable (6.56e-6)" "unprognostic (8.84e-2)" "unprognostic (6.44e-3)" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (5.06e-2)" "unprognostic (1.73e-1)" 12.1 18.5 33.2 12.3 34.0 3.0 7.4 30.8 28.8 9.2 21.3 7.9 5.6 11.9 4.2 4.3 8.7 9.0 36.0 28.1 30.8 8.1 3.8 16.0 7.8 38.7 36.3 13.4 5.7 3.9 13.7 19.9 36.6 6.5 5.2 67.6 5.6 4.5 7.5 4.6 8.2 11.5 37.1 18.3 5.1 13.2 36.1 3.2 6.1 7.0 6.6 8.5 6.6 36.4 1.1 5.6 46.1 13.8 11.6 8.4 2.3 4.0 1.3 3.4 1.4 1.5 3.1 2.1 2.8 3.2 4.2 1.3 7.3 1.5 1.0 25.0 5.3 35.1 3.4 1.5 6.9 1.5 3.5 4.5 0.3 1.3 0.2 10.4 85.0 6.2 1.6 0.4 1.1 7.1 1.3 3.0 4.7 1.4 2.8 1.3 4.6 1.0 0.9 2.6 19.1 14.8 4.6 1.8 2.2 9.1 7.8 7.4 24.2 4.3 9.6 5.2 2.0 2.0 1.1 1.2 6.1 11.2 8.3 0.0 0.8 0.0 0.6 2.0 0.5 0.1 0.3 0.3 1.3 0.3 0.2 0.3 0.0 0.2 2.7 2.4 0.1 0.5 33.2 34.0 30.8 28.8 28.1 30.8 38.7 36.3 36.6 37.1 36.1 36.4 17.3 0.0 2.3 7.2 2.7 0.6 0.0 0.3 0.0 9.4 0.9 2.4 10.9 1.5 0.7 1.8 139.7 0.4 11.1 0.0 0.0 0.9 72.8 0.8 7.7 27.5 6.7 0.0 13.4 0.0 0.3 7.6 1.5 0.6 12.0 18.1 31.8 1.2 14.8 0.0 11.9 0.4 2.0 14.2 9.3 95.3 1.8 23.6 1.8 53.4 7.6 15.2 3.1 21.6 21.8 0.3 0.0 3.0 0.4 0.0 0.0 0.2 0.0 98.8 13.1 5.5 10.0 0.8 2.3 0.4 0.1 0.3 1.8 5.7 0.2 0.1 VASH2 FLJ12505 ENSG00000143494 "Vasohibin 2" Q86V25 1 212950520-212992037 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.9" "Group enriched" "Detected in many" 6 "Early spermatids: 92.8;Late spermatids: 80.8" "Cancer enhanced" "Detected in many" "testis cancer: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 24.2;AN3-CA: 29.6;NTERA-2: 46.2;RH-30: 135.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045820 Approved Cytosol "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA045820: " "unprognostic (2.22e-1)" "unprognostic (1.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.57e-2)" "unprognostic (1.25e-2)" "unprognostic (4.04e-2)" "unprognostic (2.59e-3)" "unprognostic (3.50e-2)" "unprognostic (2.45e-1)" "unprognostic (6.58e-2)" "unprognostic (1.84e-5)" "unprognostic (1.95e-3)" "unprognostic (2.74e-1)" "unprognostic (6.85e-2)" "unprognostic (6.81e-4)" 1.7 0.1 0.9 3.3 0.8 0.9 2.0 0.2 1.1 1.7 0.0 0.5 0.7 1.9 0.4 4.0 0.7 2.6 1.1 0.6 0.4 0.4 0.2 1.1 2.3 1.6 0.9 0.6 0.2 0.8 2.6 0.8 1.6 2.7 0.6 0.5 0.9 0.8 0.5 0.5 0.9 1.8 0.2 1.2 0.8 7.9 2.1 4.3 0.3 0.8 2.1 1.4 0.5 0.7 0.3 1.7 24.2 29.6 0.2 0.1 4.0 0.1 0.0 1.0 1.3 0.1 0.6 0.1 0.4 0.1 0.6 0.1 9.9 0.0 1.2 20.3 3.7 2.0 1.4 1.5 0.1 0.2 0.4 3.8 0.0 1.3 0.0 0.6 0.3 11.4 0.1 5.9 2.0 0.5 13.1 1.5 46.2 0.0 3.6 7.6 135.5 1.3 0.2 1.9 5.6 8.6 3.1 0.2 0.3 12.4 4.5 0.9 0.0 1.0 2.7 0.6 1.3 3.4 6.2 0.9 0.1 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.8 0.2 1.1 0.6 0.4 1.6 0.9 1.6 0.2 2.1 0.7 0.9 0.0 1.1 0.0 0.6 1.5 0.8 0.2 5.7 3.0 4.1 6.0 1.2 0.0 0.0 0.0 2.1 0.1 12.6 0.2 0.0 0.7 92.8 0.9 1.4 1.1 1.2 0.8 5.4 0.2 0.3 10.9 2.0 1.0 0.0 11.2 0.0 0.1 0.2 1.7 4.3 0.2 2.0 0.3 3.2 80.8 0.3 1.5 0.0 0.0 0.7 0.4 0.0 0.5 0.6 0.1 0.0 0.7 1.0 1.5 0.0 0.4 0.9 2.0 0.0 8.4 4.0 3.2 1.1 0.4 1.6 0.0 0.5 0.1 0.3 0.4 VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 58.7;Fibroblasts: 104.2;Leydig cells: 50.1;Peritubular cells: 60.9;Sertoli cells: 98.6;Smooth muscle cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 21.8;MCF7: 18.4;U-2197: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" NA Yes 2000000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" 55.7 15.5 1.5 5.8 2.3 2.7 31.5 0.8 2.3 48.1 3.0 12.1 3.4 30.3 0.0 34.1 24.6 7.3 30.5 1.1 0.5 56.1 31.8 44.9 2.8 6.3 5.5 40.0 10.3 0.0 12.8 10.4 1.7 17.9 0.0 0.3 15.9 0.0 6.9 38.8 11.2 0.0 1.6 13.0 13.4 16.8 4.6 0.0 26.8 0.0 0.0 26.5 38.9 2.7 4.2 0.0 0.6 0.5 0.2 0.2 12.6 21.8 0.1 0.0 0.0 1.9 5.5 0.0 4.5 0.3 2.6 0.3 0.0 0.0 0.0 13.7 2.2 0.9 15.9 14.9 0.6 0.0 0.4 7.9 0.0 0.3 0.0 3.1 0.0 0.1 3.1 0.8 0.0 18.4 1.0 5.3 2.2 0.4 2.4 1.0 0.0 0.0 0.0 0.1 1.4 9.3 6.5 13.5 0.6 2.2 6.8 2.5 0.0 17.5 12.5 78.4 4.6 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 0.8 2.3 1.1 0.5 6.3 5.5 1.7 1.6 4.6 2.7 10.0 6.4 13.1 5.5 1.4 9.6 7.8 4.2 9.1 0.5 21.9 10.9 16.2 32.9 6.4 23.9 0.0 5.4 2.8 1.5 7.9 13.1 1.1 12.1 58.7 4.6 0.0 0.0 1.1 2.9 7.2 104.2 16.8 20.5 3.8 4.6 2.9 15.3 3.4 0.0 0.9 2.0 2.0 0.6 21.7 2.8 50.1 2.0 14.2 2.8 0.0 18.3 0.0 0.5 0.3 28.3 1.2 60.9 0.8 6.4 0.2 12.3 2.7 0.7 98.6 12.6 80.9 0.8 4.1 3.7 7.5 10.0 3.5 2.3 0.8 4.9 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 349.4;Muller glia cells: 265.8" "Cancer enhanced" "Detected in all" "renal cancer: 79.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 398.9;U-87 MG: 628.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" NA NA 562000 57000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "CAB005429: AB_2212984, CAB039240: , CAB069907: AB_10001947, HPA069116: AB_2686089" "unprognostic (1.12e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (2.42e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.34e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (1.76e-5)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.73e-4)" 155.8 52.7 17.6 36.5 20.3 45.5 92.4 34.2 28.2 45.2 46.8 32.6 50.9 104.0 10.5 61.3 40.9 80.1 208.3 22.8 25.1 116.9 217.3 94.1 9.3 27.0 38.5 25.0 68.1 105.0 22.3 46.2 26.8 120.3 21.4 229.1 32.1 17.8 221.2 44.2 44.6 57.1 19.6 70.1 63.9 5.3 32.0 5.6 270.9 150.9 9.5 122.3 61.7 24.9 76.5 13.4 12.5 71.8 21.0 32.9 84.2 45.6 81.1 29.7 58.4 43.1 9.9 24.9 35.5 27.7 305.4 30.6 34.0 92.0 52.0 27.4 10.4 19.0 17.8 29.2 220.3 20.8 40.4 58.0 178.6 290.6 286.2 398.9 7.7 21.0 35.7 121.7 109.4 31.3 2.3 28.3 7.9 221.2 19.2 2.3 12.0 60.5 114.8 62.9 22.3 46.8 65.6 44.4 162.0 16.1 17.3 75.1 10.4 122.6 32.9 179.2 76.1 68.8 43.6 49.1 628.6 47.9 43.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 20.3 34.2 28.2 22.8 25.1 27.0 38.5 26.8 19.6 32.0 24.9 63.6 349.4 84.7 121.5 9.8 70.5 51.2 76.8 60.3 37.8 67.0 57.1 164.7 77.2 85.7 22.0 31.3 1.3 11.6 92.9 1.9 54.7 0.0 38.4 59.1 29.0 27.4 21.3 12.1 40.8 6.3 69.7 124.4 121.2 112.0 111.7 17.5 116.0 13.9 180.0 17.0 71.8 12.2 16.2 199.0 0.3 1.8 144.1 28.4 10.3 11.3 265.8 0.0 124.1 1.8 86.0 47.1 3.4 15.9 119.4 61.9 20.5 11.4 43.9 0.0 42.1 79.1 1.1 1.9 82.0 78.3 7.9 11.4 17.4 51.0 137.5 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.9;Muller glia cells: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 209.8 82.0 45.7 12.0 51.3 3.9 151.3 41.8 53.1 103.6 48.2 151.5 12.1 99.9 7.2 50.8 72.5 19.2 253.3 38.7 45.1 84.6 44.0 82.5 14.4 54.8 47.4 82.6 84.9 18.3 104.2 9.8 45.0 92.7 4.7 12.7 57.7 28.5 143.8 77.3 59.5 10.2 44.2 55.9 89.2 17.5 50.6 6.6 83.7 51.5 9.1 118.0 77.5 37.3 15.4 25.9 9.9 28.1 49.7 36.8 12.7 14.7 27.8 13.1 16.0 13.8 31.7 19.8 28.6 14.0 28.8 20.8 15.8 11.5 2.3 20.6 15.1 16.7 33.9 13.3 45.4 4.8 20.1 39.6 12.0 19.6 12.2 33.9 18.4 20.6 20.2 32.5 22.2 31.8 27.4 12.6 7.0 10.9 22.3 32.1 20.5 46.5 11.0 19.5 14.0 46.4 12.4 38.1 57.4 7.6 25.1 5.6 13.0 50.8 30.2 23.1 8.7 90.5 45.5 15.4 41.6 5.3 25.1 0.3 0.2 0.6 0.9 0.0 0.8 3.0 0.8 0.9 0.4 2.4 0.9 1.6 0.0 0.4 0.0 30.5 0.5 0.4 45.7 51.3 41.8 53.1 38.7 45.1 54.8 47.4 45.0 44.2 50.6 37.3 54.1 19.2 32.6 43.8 27.6 12.7 6.7 10.1 2.2 47.9 32.8 65.7 204.9 10.0 7.6 14.7 33.3 9.6 68.3 11.9 39.2 14.8 1.1 24.2 47.7 21.9 53.3 4.4 7.3 12.9 16.8 68.6 5.1 31.6 18.4 62.7 19.6 9.8 51.4 65.6 26.6 12.2 20.3 31.5 21.5 3.5 60.9 50.0 35.6 19.7 17.7 130.6 12.3 29.1 11.8 14.5 7.3 109.1 12.3 11.5 20.3 31.6 8.9 39.6 6.6 47.4 53.7 0.5 1.2 6.4 13.9 8.9 19.0 34.3 12.8 7.5 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VEGFD "FIGF, VEGF-D" ENSG00000165197 "Vascular endothelial growth factor D" O43915 X 15345596-15384413 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 42.7" "Cell type enriched" "Detected in some" 12 "Fibroblasts: 39.8" "Cancer enhanced" "Detected in some" "liver cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.4;ASC TERT1: 2.8;EFO-21: 1.3;HSkMC: 2.8" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 3.5;hippocampal formation: 3.3;white matter: 2.6" "Not detected" "Not detected" HPA027342 Uncertain "Secreted to blood" NA NA 592000 450000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA027342: AB_1848597" "unprognostic (5.90e-2)" "unprognostic (9.79e-3)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-1)" "unprognostic (6.06e-3)" "unprognostic (5.57e-2)" "unprognostic (2.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.59e-5)" "unprognostic (3.08e-2)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (1.75e-2)" 11.4 9.9 1.8 0.7 1.8 0.0 20.3 1.5 2.3 19.2 1.5 5.0 1.2 3.8 4.9 2.7 4.1 2.8 15.5 1.6 2.0 1.7 1.5 42.7 0.4 1.8 1.7 4.4 0.7 2.7 7.0 0.2 2.0 1.5 2.0 0.3 2.3 1.8 17.6 1.2 4.2 3.3 1.3 2.8 5.8 0.6 2.1 0.3 1.5 23.0 1.3 6.0 8.1 2.0 0.0 0.6 0.5 0.9 3.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.3 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.3 2.8 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.3 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.5 2.3 1.6 2.0 1.8 1.7 2.0 1.3 2.1 2.0 3.1 3.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 39.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.3 1.6 0.0 0.0 VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 1407.4" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 128.3;Horizontal cells: 225.4" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Region enriched" "Detected in all" 6 "hypothalamus: 1407.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 172.0;SK-MEL-30: 511.5;U-2 OS: 85.9;WM-115: 141.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1270000 3100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavorable (4.25e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" 2.1 3.1 23.7 0.8 24.8 0.1 0.1 5.5 174.6 0.0 0.0 0.5 0.1 0.7 0.0 0.0 0.0 0.0 0.1 22.7 1407.4 3.6 0.0 0.1 0.0 235.4 69.9 0.1 16.1 0.0 117.0 0.0 158.8 0.1 0.0 2.2 0.0 0.0 0.0 0.8 0.3 0.2 16.6 0.1 1.9 0.9 48.7 0.0 0.6 0.0 0.0 0.0 0.1 27.3 2.2 1.1 1.1 9.5 0.0 0.0 10.3 0.9 0.0 0.0 0.0 2.4 0.9 0.1 3.1 0.0 1.4 1.4 0.5 0.1 0.0 1.0 0.7 0.3 0.0 0.9 0.1 0.6 4.4 0.1 0.2 0.2 0.7 0.0 0.0 0.1 3.7 2.3 0.0 23.4 0.1 2.4 17.6 1.0 2.3 0.8 0.0 0.1 0.3 0.1 14.1 172.0 0.3 0.9 511.5 1.1 0.4 0.3 0.0 0.4 85.9 0.0 2.0 0.1 0.8 4.7 13.5 0.4 141.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 24.8 5.5 174.6 22.7 1407.4 235.4 69.9 158.8 16.6 48.7 27.3 1.7 0.0 0.0 3.6 0.9 1.5 1.0 0.0 1.2 22.0 0.9 0.6 2.9 0.0 0.0 0.0 0.0 1.5 1.0 1.3 29.4 0.3 0.1 0.4 0.4 0.9 128.3 0.0 22.7 0.0 8.4 0.3 3.1 0.5 0.0 1.4 0.0 0.0 0.6 225.4 37.7 4.5 0.0 0.0 0.4 0.6 0.6 0.7 0.0 11.2 0.0 2.1 0.0 4.0 4.8 5.9 2.8 0.0 0.9 4.3 2.7 1.2 0.0 5.0 0.0 0.1 0.8 0.2 4.3 0.6 2.3 1.4 0.5 5.4 2.3 0.6 VIP ENSG00000146469 "Vasoactive intestinal peptide" P01282 6 152750797-152759765 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.2;lymphoid tissue: 155.5" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 80.6;Melanocytes: 28.4" "Group enriched" "Detected in some" 6 "colorectal cancer: 3.7;pancreatic cancer: 4.3;stomach cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 2.7;TIME: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017324, CAB018649, HPA072701, CAB079780" Supported Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 122000 "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB018649: AB_2304501, CAB079780: , HPA017324: AB_1858754, HPA072701: AB_2686550" "unprognostic (9.58e-2)" "unprognostic (2.29e-2)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (3.62e-1)" "unprognostic (2.92e-3)" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (5.90e-2)" 2.7 12.2 5.5 155.5 7.9 0.1 1.9 4.9 10.9 1.8 4.6 72.2 16.6 1.2 0.4 4.3 1.5 3.7 4.3 7.3 28.7 2.5 1.1 3.4 0.4 6.9 40.0 0.8 8.3 0.3 0.8 0.6 7.7 2.7 61.4 1.0 0.5 0.5 1.4 0.4 45.8 41.6 4.8 9.7 22.2 1.0 11.9 0.1 2.3 1.7 0.1 1.6 9.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 7.9 4.9 10.9 7.3 28.7 6.9 40.0 7.7 4.8 11.9 5.9 2.5 0.0 0.0 3.3 0.2 0.4 0.0 0.0 0.0 1.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 80.6 0.0 0.0 0.3 0.0 6.5 0.0 0.0 28.4 4.7 0.0 0.0 0.0 2.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 68.3;Fibroblasts: 58.8;Granulosa cells: 45.1;Leydig cells: 115.2;Skeletal myocytes: 45.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "ASC diff: 33.6;ASC TERT1: 65.2;BJ: 32.9;fHDF/TERT166: 112.3;SuSa: 62.2;THP-1: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" 35.4 0.9 0.2 0.5 0.5 0.9 15.4 0.8 0.9 6.0 0.4 3.9 0.4 1.0 0.6 8.7 7.9 2.3 18.6 0.3 0.1 0.2 0.0 1.2 2.3 0.1 0.1 28.7 1.0 0.6 3.1 2.2 0.1 7.0 1.5 0.0 11.6 2.3 12.5 12.7 2.7 0.2 0.0 0.1 4.7 3.0 0.3 1.0 8.9 41.1 2.2 15.0 14.6 0.2 0.0 0.0 0.0 0.0 33.6 65.2 0.0 32.9 7.7 10.4 4.3 0.0 0.0 0.0 0.0 112.3 0.1 0.2 6.2 0.0 6.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.3 1.6 0.0 0.0 0.0 2.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.7 0.0 62.2 0.0 35.6 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 2.5 2.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.5 0.8 0.9 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.2 4.1 0.0 0.0 0.7 0.0 4.2 0.9 0.0 68.3 0.0 0.2 10.0 3.2 0.0 0.0 0.0 0.0 10.6 0.9 0.3 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.0 1.8 0.0 11.0 58.8 0.0 0.0 0.0 45.1 0.4 0.0 1.1 0.0 0.7 0.4 0.0 0.0 3.5 2.7 115.2 0.5 7.2 20.6 0.0 0.0 4.1 0.5 0.3 0.0 0.1 23.3 0.8 0.1 0.0 0.0 0.0 0.0 6.6 45.2 6.1 1.1 0.6 1.6 3.4 4.2 1.1 0.1 0.3 0.2 VMO1 ENSG00000182853 "Vitelline membrane outer layer 1 homolog" Q7Z5L0 17 4785285-4786433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.8;pituitary gland: 27.7" "Group enriched" "Detected in many" 4 "Club cells: 923.5;monocytes: 857.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "non-classical monocyte: 111.9" "Lineage enriched" "Detected in many" 9 "monocytes: 111.9" "Cell line enhanced" "Detected in some" "A549: 3.0;MCF7: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023038 Uncertain "Secreted to blood" NA NA 2900000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA023038: AB_10964632" "unprognostic (1.30e-1)" "unprognostic (5.71e-2)" "unprognostic (1.65e-3)" "unprognostic (9.09e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (5.58e-3)" "unprognostic (1.20e-1)" "unprognostic (1.65e-1)" "unprognostic (7.41e-2)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.34e-6)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-1)" "unprognostic (2.69e-1)" 5.1 2.5 4.5 7.0 4.5 2.4 2.3 4.7 6.5 3.1 6.7 2.1 4.9 1.6 0.1 1.7 1.6 3.4 2.3 4.5 5.2 5.5 10.4 8.9 2.0 6.1 4.7 1.0 2.3 13.3 27.7 2.3 5.1 3.0 0.8 0.5 5.2 1.6 10.1 2.0 5.6 0.9 5.3 21.8 1.6 0.7 5.1 2.1 1.4 1.5 0.5 4.7 2.5 6.1 0.2 3.0 0.3 1.8 0.3 0.7 0.3 0.6 1.1 0.1 0.3 0.9 1.1 0.1 0.0 0.1 0.2 0.5 0.0 0.4 0.2 2.2 0.4 0.1 0.6 0.8 0.6 0.0 1.3 0.5 0.4 0.1 0.4 0.6 0.0 0.4 0.3 0.4 0.6 3.9 0.0 0.9 0.7 0.7 1.3 0.7 1.5 0.3 0.0 0.7 0.2 0.4 0.2 0.2 0.3 0.2 1.2 0.1 0.3 1.2 0.1 0.3 0.2 0.0 0.3 0.0 0.5 0.6 0.9 0.1 0.2 0.0 0.0 9.7 0.0 0.0 0.0 0.0 12.3 0.1 0.0 0.1 0.0 0.4 111.9 0.0 0.0 3.7 4.5 4.5 4.7 6.5 4.5 5.2 6.1 4.7 5.1 5.3 5.1 6.1 2.8 3.2 7.7 1.0 2.8 8.5 13.4 217.2 0.6 6.7 2.8 3.7 0.9 1.5 923.5 0.0 0.0 0.4 0.8 1.1 1.9 0.9 8.2 0.4 0.8 5.2 1.2 3.2 0.5 1.5 0.3 2.5 0.0 0.4 14.0 0.3 79.6 3.3 16.2 0.0 0.9 1.0 101.7 59.8 210.9 40.3 0.3 70.8 5.4 1.0 857.9 1.0 0.0 0.0 0.6 1.5 0.3 1.2 0.7 11.2 4.3 2.4 158.4 2.9 13.1 1.3 45.5 0.6 1.5 0.8 7.2 0.3 2.0 0.5 1.3 14.2 VNN3 HSA238982 ENSG00000093134 "Vanin 3" Q9NY84 6 132722787-132736935 "Enzymes, Metabolic proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 34.9;liver: 34.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 20.7;Club cells: 42.5;Gastric mucus-secreting cells: 15.8;Respiratory ciliated cells: 86.1" "Cancer enriched" "Detected in some" 4 "liver cancer: 3.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "neutrophil: 76.2" "Lineage enriched" "Detected in many" 33 "granulocytes: 76.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 150000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.20e-2)" "unprognostic (2.70e-1)" "unprognostic (7.92e-3)" "unprognostic (1.71e-2)" "unprognostic (3.05e-3)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.01e-1)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (5.84e-8)" "unprognostic (1.25e-2)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" 1.2 0.1 0.1 2.2 0.1 34.9 0.2 0.1 0.5 1.6 0.2 0.1 0.0 0.1 0.0 0.8 1.9 1.0 0.4 0.1 0.1 0.3 34.7 4.5 0.4 0.1 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.3 0.0 0.0 1.0 0.1 0.1 0.2 0.2 0.2 0.1 5.5 0.4 0.1 0.2 0.4 0.1 1.1 0.4 0.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.2 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.1 20.7 0.0 0.0 0.2 0.0 0.4 0.0 42.5 0.0 0.0 0.0 0.1 0.2 0.0 3.7 0.2 2.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.8 1.7 0.0 0.0 0.4 10.0 0.1 0.0 0.0 0.0 6.1 5.8 0.0 0.2 0.0 3.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.0 0.0 0.1 86.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.0 0.2 0.2 0.3 4.1 VSTM1 UNQ3033 ENSG00000189068 "V-set and transmembrane domain containing 1" Q6UX27 19 54040825-54063953 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 43.2" "Cell type enhanced" "Detected in some" "Early spermatids: 3.4;Late spermatids: 20.3;Macrophages: 4.5;monocytes: 12.4;NK-cells: 3.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "eosinophil: 129.2" "Lineage enriched" "Detected in many" 16 "granulocytes: 129.2" "Cell line enhanced" "Detected in some" "HMC-1: 1.0;hTERT-HME1: 1.0;U-2 OS: 1.0" "Low region specificity" "Detected in all" HPA059365 Approved Vesicles "Secreted to blood" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA059365: " "unprognostic (5.13e-2)" "unprognostic (5.31e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (9.47e-2)" "unprognostic (1.31e-5)" "unprognostic (3.73e-1)" "unprognostic (1.14e-1)" "unprognostic (9.74e-2)" "unprognostic (4.67e-2)" 0.2 0.1 0.0 0.2 0.0 43.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.0 1.4 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 7.4 129.2 0.0 6.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 8.1 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 2.1 0.0 0.4 0.0 0.0 2.5 0.0 20.3 0.0 4.5 0.0 0.0 12.4 0.0 3.1 0.5 0.6 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 VSTM2A "MGC33530, VSTM2" ENSG00000170419 "V-set and transmembrane domain containing 2A" Q8TAG5 7 54542325-54571080 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.2;brain: 31.3;prostate: 9.7;retina: 14.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.0;Enteroendocrine cells: 7.3;Excitatory neurons: 12.5;Fibroblasts: 10.9;Inhibitory neurons: 30.1" "Cancer enhanced" "Detected in some" "breast cancer: 4.6;glioma: 3.0" "Region enhanced" "Detected in many" "cerebral cortex: 31.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 4.2;SH-SY5Y: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 31000 "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (1.89e-1)" "unprognostic (1.14e-2)" "unprognostic (4.66e-1)" "prognostic favorable (5.34e-4)" "unprognostic (4.34e-2)" "unprognostic (6.79e-2)" "unprognostic (7.15e-2)" 0.0 10.2 4.4 0.0 9.9 0.0 0.3 0.0 31.3 0.0 0.0 4.4 1.4 0.0 0.0 0.0 0.0 0.1 0.0 10.5 6.6 0.0 0.0 0.0 0.0 2.2 1.5 0.0 0.6 0.0 0.3 0.0 0.0 9.7 4.0 14.3 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 4.7 0.4 13.7 0.0 0.2 0.2 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.2 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 9.9 0.0 31.3 10.5 6.6 2.2 1.5 0.0 0.7 13.7 2.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 7.3 0.0 12.5 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 2.5 0.5 0.0 1.1 0.0 0.0 0.2 0.0 0.1 0.7 4.1 0.0 0.2 2.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.4 0.3 VSTM2L "C20orf102, dJ1118M15.2" ENSG00000132821 "V-set and transmembrane domain containing 2 like" Q96N03 20 37903111-37945350 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 87.0;heart muscle: 81.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 25.2;Cholangiocytes: 61.5;Club cells: 28.7;Inhibitory neurons: 44.0;Respiratory ciliated cells: 83.0" "Group enriched" "Detected in all" 5 "lung cancer: 23.6;pancreatic cancer: 34.4;prostate cancer: 72.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 67.2;HDLM-2: 98.8;hTCEpi: 23.4;SH-SY5Y: 22.5;SK-BR-3: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043832 Uncertain "Secreted - unknown location" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA043832: AB_10968449" "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.63e-5)" "unprognostic (4.96e-3)" "unprognostic (1.56e-1)" "unprognostic (1.83e-2)" "unprognostic (1.39e-1)" "unprognostic (1.52e-1)" "unprognostic (2.34e-3)" "unprognostic (9.86e-2)" "unprognostic (2.00e-1)" "unprognostic (1.85e-3)" "unprognostic (1.29e-3)" "unprognostic (1.68e-1)" "unprognostic (9.66e-2)" "prognostic unfavorable (8.14e-4)" 0.7 6.1 33.9 0.8 33.8 0.0 0.5 1.3 76.9 12.5 0.0 3.2 1.2 1.7 9.7 1.0 15.5 17.5 81.8 87.0 38.7 1.4 3.0 11.5 0.4 19.1 36.5 0.3 2.6 0.0 17.3 0.8 10.6 9.2 0.4 3.0 7.3 16.2 1.1 1.0 1.2 0.8 41.8 29.6 7.9 4.9 45.9 3.0 1.7 0.0 1.0 0.7 0.6 20.0 0.0 0.8 7.7 0.3 0.3 0.4 0.2 0.9 0.0 0.0 0.0 0.3 67.2 0.0 0.4 0.6 0.3 0.2 0.1 3.2 0.0 98.8 1.9 0.1 0.1 0.0 3.6 0.1 2.5 3.2 23.4 0.1 0.7 2.4 0.0 0.1 0.0 0.0 8.4 0.0 0.1 0.1 0.2 2.3 20.1 0.0 0.0 0.3 0.1 0.0 2.6 22.5 2.7 81.0 0.8 0.0 0.4 0.0 4.6 0.0 0.6 0.2 1.5 0.2 0.1 0.0 0.5 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 33.8 1.3 76.9 87.0 38.7 19.1 36.5 10.6 41.8 45.9 20.0 0.1 6.4 1.8 2.0 0.1 0.4 1.2 10.7 1.8 8.5 1.0 0.0 25.2 61.5 28.7 0.0 8.4 0.6 1.3 0.2 0.0 3.7 0.4 0.1 0.5 0.3 18.6 0.0 17.8 0.2 0.2 1.8 4.1 0.0 0.0 1.5 2.9 1.3 0.0 13.5 44.0 1.2 10.2 0.8 1.5 0.9 5.3 0.9 0.0 1.9 0.0 0.9 0.0 3.0 3.2 7.9 2.6 16.1 0.1 5.3 0.1 1.0 83.0 4.6 0.0 0.0 2.9 0.2 0.8 0.1 0.6 0.1 1.2 3.5 0.2 0.7 VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Granulosa cells: 96.9;Late spermatids: 140.6;Sertoli cells: 59.2;Theca cells: 44.7" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 8.6;RH-30: 9.3;SH-SY5Y: 7.9;U-138 MG: 10.6;U-2197: 24.0;U-87 MG: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" 18.7 41.5 7.1 3.2 9.0 0.3 9.8 8.0 6.6 22.3 7.7 7.8 2.5 12.3 7.4 7.8 8.5 10.5 12.3 6.2 7.6 12.3 3.9 10.9 3.5 8.9 9.3 35.2 1.5 26.8 5.1 10.4 9.2 13.5 5.6 2.3 3.4 11.7 5.6 4.9 4.9 11.4 8.6 2.3 5.6 9.4 8.4 6.5 27.8 5.9 4.6 12.0 7.5 9.4 0.0 0.0 3.1 0.1 1.3 0.7 0.1 2.6 4.1 0.9 0.2 0.0 0.1 0.1 0.1 6.1 3.4 0.1 0.2 0.0 0.4 3.2 1.4 0.2 0.1 0.1 0.1 0.1 0.0 4.7 0.0 4.2 0.0 0.0 0.0 0.8 8.6 0.1 0.8 0.1 0.0 0.2 0.6 0.0 0.0 0.0 9.3 5.0 0.0 0.1 0.1 7.9 0.1 0.0 0.0 0.4 0.1 0.3 0.0 10.6 1.2 24.0 0.1 0.0 6.8 0.0 11.6 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.3 0.1 0.1 0.0 0.0 7.1 9.0 8.0 6.6 6.2 7.6 8.9 9.3 9.2 8.6 8.4 9.4 9.4 3.2 17.5 17.3 1.3 6.5 1.6 0.1 0.6 5.4 1.2 1.1 16.7 0.0 9.4 0.0 2.1 0.4 3.7 0.2 1.9 0.1 88.5 0.8 10.7 6.2 0.0 0.0 11.1 0.0 0.3 29.7 0.0 0.7 12.6 96.9 5.3 5.0 0.7 5.0 7.0 0.0 0.0 2.2 11.1 140.6 9.6 2.9 7.2 4.7 1.0 9.1 2.1 20.1 33.3 0.2 0.1 14.7 0.7 0.8 0.0 9.4 3.8 2.9 59.2 20.6 37.7 1.3 4.4 0.4 4.3 0.4 2.0 44.7 0.0 0.7 VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 6039.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 5507.4" "Cancer enriched" "Detected in many" 85 "liver cancer: 2216.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "CACO-2: 1748.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 606000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Vesicles" "CAB016695: AB_1624536, CAB016765: , HPA060933: AB_2684389, HPA068011: " "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.13e-2)" "unprognostic (9.74e-2)" "unprognostic (8.42e-2)" "prognostic favorable (3.74e-4)" "unprognostic (6.20e-2)" "unprognostic (3.97e-1)" "unprognostic (8.95e-2)" "unprognostic (3.24e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.10e-11)" "unprognostic (8.82e-3)" "unprognostic (2.27e-1)" "unprognostic (4.86e-3)" "unprognostic (7.09e-2)" 6.2 98.9 2.4 2.5 2.7 0.3 0.9 5.4 3.7 1.0 0.4 0.9 4.6 1.4 0.9 0.5 2.2 61.2 53.1 2.5 2.8 3.6 6039.5 1.8 4.3 2.1 5.3 1.9 17.7 0.1 3.0 40.6 2.3 1.2 0.3 47.4 0.6 4.3 0.4 0.8 1.3 2.7 1.5 2.9 5.1 10.0 2.2 0.1 0.8 0.5 0.4 4.2 0.7 2.4 0.0 28.4 0.7 0.4 0.2 0.3 7.3 1.8 0.8 0.9 0.9 1748.9 0.1 1.2 0.2 0.2 0.2 0.7 0.0 0.0 0.1 0.2 0.2 1.2 1.1 86.7 2.5 6.1 0.5 0.4 0.0 0.6 0.0 3.9 0.1 0.0 1.6 0.3 0.2 0.7 0.2 0.0 0.8 0.4 0.1 0.4 3.5 0.1 0.3 0.0 1.0 1.4 115.6 8.0 0.2 4.3 0.3 0.0 1.0 0.4 0.3 0.1 0.2 1.0 0.5 1.4 0.5 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 2.4 2.7 5.4 3.7 2.5 2.8 2.1 5.3 2.3 1.5 2.2 2.4 0.1 0.0 1.1 2.0 21.5 0.0 0.0 0.0 0.0 13.0 0.1 0.1 18.1 1162.4 0.0 0.0 77.2 3.7 0.0 0.0 3.9 16.8 0.0 0.0 1.2 7.3 0.0 131.0 0.9 19.7 2.8 48.1 0.0 0.0 0.0 1.8 120.3 5507.4 4.7 38.7 1.0 0.1 0.0 160.3 0.3 0.2 0.0 0.3 0.0 0.0 20.1 6.9 0.0 1.0 0.5 23.5 1.2 1.5 0.0 0.0 0.1 9.5 0.0 38.3 0.0 0.4 1.5 4.2 0.6 0.0 0.0 9.6 9.0 0.7 0.0 0.0 VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 275.1;Endothelial cells: 142.7;Syncytiotrophoblasts: 290.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 47.2;CACO-2: 46.7;CAPAN-2: 136.6;Hep G2: 84.4;SCLC-21H: 47.6;T-47d: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 250000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (2.78e-1)" "unprognostic (4.85e-2)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (9.52e-3)" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" "unprognostic (3.08e-2)" "unprognostic (6.71e-2)" 36.2 15.2 55.3 31.5 91.7 0.2 38.4 79.4 76.7 51.0 24.4 114.3 15.3 70.4 11.5 41.3 50.4 22.4 38.0 59.4 58.9 58.6 133.3 29.6 13.7 103.4 81.6 22.5 55.3 12.5 20.0 38.4 87.9 131.3 5.3 2.3 64.0 203.6 10.1 26.2 37.6 20.4 74.2 11.7 52.6 27.1 88.3 3.0 67.4 3.4 5.1 118.5 50.6 151.2 47.2 15.4 2.2 15.7 0.4 1.4 24.5 3.1 0.1 2.2 0.1 46.7 136.6 0.0 43.0 1.3 5.0 12.1 15.9 8.1 0.3 3.0 11.3 1.5 0.1 84.4 3.5 0.0 5.5 2.7 0.4 1.0 0.0 0.4 0.6 0.0 1.6 0.0 0.1 11.7 0.1 0.9 6.1 16.5 4.3 0.6 0.8 2.2 2.7 7.9 47.6 7.4 0.0 41.7 5.8 3.7 61.1 0.6 1.4 0.1 0.6 0.4 15.2 0.3 0.2 0.2 2.3 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 91.7 79.4 76.7 59.4 58.9 103.4 81.6 87.9 74.2 88.3 151.2 103.4 19.2 36.1 5.9 2.8 6.5 19.1 5.2 12.0 7.6 40.4 59.4 3.6 44.3 14.2 53.3 4.2 275.1 1.4 24.2 7.9 82.0 0.6 16.0 46.2 142.7 12.5 2.7 0.5 65.0 99.2 28.3 16.8 17.7 1.3 2.0 8.2 49.4 22.8 15.2 1.5 8.9 6.1 1.0 4.3 4.0 34.2 1.1 24.9 18.7 2.6 52.1 0.0 13.0 48.7 48.0 11.0 59.0 2.6 21.5 0.8 5.4 10.7 4.3 6.6 62.4 17.2 0.8 2.1 11.9 8.5 290.3 1.3 6.3 10.4 14.9 VWA2 "AMACO, CCSP-2, FLJ16213, FLJ45857, NET42" ENSG00000165816 "Von Willebrand factor A domain containing 2" Q5GFL6 10 114239254-114294489 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 8.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 6.8;Early spermatids: 9.6;Gastric mucus-secreting cells: 5.1;Late spermatids: 15.8;Microglial cells: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 5.7;HaCaT: 3.0;SCLC-21H: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037847 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA037847: AB_10670961" "unprognostic (6.03e-2)" "unprognostic (8.29e-2)" "unprognostic (3.27e-2)" "unprognostic (7.33e-2)" "unprognostic (1.26e-2)" "unprognostic (6.82e-2)" "unprognostic (3.02e-2)" "unprognostic (9.33e-3)" "unprognostic (2.44e-1)" "unprognostic (3.70e-1)" "unprognostic (1.37e-3)" "unprognostic (3.14e-1)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (9.30e-2)" "unprognostic (1.22e-1)" 0.5 0.0 2.7 0.4 1.6 0.5 3.1 2.2 1.6 4.0 0.3 1.3 1.6 0.9 1.0 1.2 6.4 0.2 0.0 1.4 1.3 0.5 0.0 3.3 0.2 1.9 1.7 0.1 2.3 0.2 0.3 0.4 1.8 5.4 1.0 0.3 4.5 1.0 0.3 6.4 1.4 0.1 1.7 1.4 8.4 1.1 2.1 3.4 0.8 0.2 0.5 0.7 0.9 1.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.3 0.0 0.0 3.0 0.0 0.6 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 1.6 0.0 0.0 0.6 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.7 1.6 2.2 1.6 1.4 1.3 1.9 1.7 1.8 1.7 2.1 1.5 0.4 0.0 0.0 0.0 0.0 0.3 4.1 2.8 6.8 0.0 1.1 0.3 0.5 0.0 1.7 1.8 0.0 1.3 0.0 0.1 0.0 2.1 9.6 0.7 0.1 0.2 0.0 0.0 4.1 1.6 0.0 0.1 5.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.4 2.0 0.0 0.0 15.8 0.3 0.0 0.0 16.9 0.0 0.0 0.0 2.5 0.1 2.2 0.2 0.0 0.0 2.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.8 0.3 1.1 0.0 0.7 0.0 0.1 0.5 1.3 VWA3A "FLJ40941, FLJ46765" ENSG00000175267 "Von Willebrand factor A domain containing 3A" A6NCI4 16 22092538-22156964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.2;choroid plexus: 53.0;fallopian tube: 39.7" "Cell type enhanced" "Detected in some" "Astrocytes: 25.5;Club cells: 16.7;Endometrial ciliated cells: 45.6;Excitatory neurons: 33.8;Late spermatids: 15.2;Respiratory ciliated cells: 88.0" "Group enriched" "Detected in some" 4 "endometrial cancer: 3.2;glioma: 1.4;ovarian cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/84: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041696, HPA042044" Uncertain "Secreted - unknown location" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 49: Ciliated cells - Cilium organization" "HPA041696: AB_10964202, HPA042044: AB_10968997" "unprognostic (2.69e-2)" "unprognostic (1.54e-1)" "unprognostic (9.75e-4)" "prognostic favorable (8.15e-4)" "unprognostic (2.70e-1)" "unprognostic (4.46e-2)" "unprognostic (1.65e-2)" "unprognostic (6.79e-3)" "unprognostic (5.55e-2)" "unprognostic (2.67e-1)" "unprognostic (6.81e-2)" "unprognostic (1.40e-1)" "unprognostic (2.16e-5)" "unprognostic (1.08e-1)" "unprognostic (2.97e-1)" "unprognostic (6.24e-2)" "unprognostic (3.06e-4)" 0.3 0.3 9.6 0.0 11.9 0.4 0.3 4.1 13.2 11.0 53.0 0.3 0.1 2.5 0.1 0.1 39.7 0.0 0.8 7.8 6.5 0.5 0.1 8.8 0.1 21.0 28.2 0.5 0.3 0.1 16.6 0.1 13.3 0.4 0.1 0.3 0.1 0.1 0.1 1.9 0.3 0.1 15.1 0.3 0.2 8.2 10.1 0.1 0.5 0.2 0.2 0.1 0.1 10.9 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.2 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.9 4.1 13.2 7.8 6.5 21.0 28.2 13.3 15.1 10.1 10.9 0.3 0.0 1.1 25.5 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.6 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 45.6 0.3 0.0 0.0 0.0 33.8 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 15.2 0.3 0.2 0.0 3.7 0.0 0.0 0.0 4.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 88.0 0.0 0.0 0.0 1.2 1.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290919-20354894 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;choroid plexus: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 10.9;Inhibitory neurons: 1.8;Late spermatids: 9.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "SCLC-21H: 1.2" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" 0.0 0.4 0.8 0.1 0.9 0.0 0.0 0.1 0.1 0.0 19.1 0.0 0.0 0.0 1.3 0.0 0.3 0.2 0.0 1.1 2.9 1.3 0.0 0.1 0.1 3.7 6.3 0.0 0.0 1.1 2.9 0.1 5.1 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 3.0 0.0 0.2 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.1 0.1 1.1 2.9 3.7 6.3 5.1 1.5 3.0 0.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 VWA7 "C6orf27, G7c, NG37" ENSG00000204396 "Von Willebrand factor A domain containing 7" Q9Y334 6 31765590-31777328 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 21.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 4.2;Gastric mucus-secreting cells: 8.2;Proximal enterocytes: 5.0;Proximal tubular cells: 2.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 2.9;hypothalamus: 8.2;medulla oblongata: 5.9;pons: 5.5;thalamus: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.2;HMC-1: 1.3;Karpas-707: 1.1;U-266/84: 1.6" "Group enriched" "Detected in some" 5 "cerebellum: 7.0;pons and medulla: 3.9" "Low region specificity" "Detected in many" "HPA046954, HPA054262" Approved Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 9200 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA046954: AB_2679875, HPA054262: AB_2682430" "unprognostic (9.13e-2)" "unprognostic (8.60e-4)" "unprognostic (9.99e-2)" "unprognostic (2.43e-1)" "unprognostic (2.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (4.40e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-2)" "unprognostic (1.65e-2)" "unprognostic (9.25e-2)" "prognostic favorable (4.35e-8)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (9.48e-2)" "unprognostic (7.66e-2)" 0.4 0.3 0.5 0.1 0.3 0.0 0.7 0.1 2.9 0.8 0.0 1.3 1.0 4.6 0.0 0.4 7.2 0.7 5.2 0.8 8.2 5.7 1.4 1.4 0.1 5.9 1.0 0.5 2.6 1.7 21.3 0.0 5.5 0.8 0.4 0.2 1.4 1.3 6.6 0.8 2.3 0.0 0.0 0.5 3.0 0.7 7.5 0.0 1.8 0.0 0.1 0.6 0.7 1.0 0.8 1.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 0.9 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.6 0.1 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.1 2.9 0.8 8.2 5.9 1.0 5.5 0.0 7.5 1.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 0.5 1.2 0.5 0.1 0.3 0.8 0.0 0.3 1.8 0.0 0.0 0.2 1.4 1.9 0.6 0.0 1.5 0.1 0.1 4.2 0.0 1.5 0.5 0.0 0.1 8.2 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 2.1 0.0 0.4 0.3 5.0 2.4 1.6 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 0.4 0.0 0.5 0.4 VWC2 "PSST739, UNQ739" ENSG00000188730 "Von Willebrand factor C domain containing 2" Q2TAL6 7 49773638-49921950 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.9;heart muscle: 5.0;ovary: 4.9" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 361.7;Oligodendrocyte precursor cells: 163.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 8.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA055243 Approved "Secreted to extracellular matrix" NA NA 39000 "Cluster 21: Non-specific - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055243: AB_2682755" "unprognostic (3.30e-1)" "unprognostic (1.04e-1)" "unprognostic (8.90e-4)" "unprognostic (8.97e-2)" "unprognostic (8.77e-2)" "unprognostic (1.56e-3)" "unprognostic (3.41e-2)" "unprognostic (4.11e-1)" "unprognostic (6.65e-2)" "unprognostic (1.69e-4)" "unprognostic (1.60e-2)" "unprognostic (2.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.94e-1)" "unprognostic (9.70e-3)" 0.1 0.0 2.5 0.0 2.6 0.0 0.0 8.9 1.7 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 5.0 0.6 1.6 0.1 0.0 0.1 0.0 0.8 1.9 4.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.1 0.4 0.3 0.1 0.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.6 8.9 1.7 0.6 1.6 0.8 1.9 0.9 0.3 4.0 0.5 0.0 0.0 0.0 3.3 0.0 0.5 0.1 0.0 10.8 22.6 0.0 0.0 50.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 18.4 0.5 0.0 0.0 65.2 0.0 0.0 1.6 0.0 0.4 0.0 47.6 0.0 0.0 0.0 1.7 361.7 0.2 0.0 0.0 1.6 0.0 0.0 0.3 0.0 10.3 0.0 0.9 0.0 163.3 1.7 0.0 7.3 0.0 0.1 0.2 0.1 0.0 0.0 13.5 0.0 0.1 2.7 0.0 0.4 0.7 2.0 0.0 0.3 0.6 0.3 0.2 VWC2L ENSG00000174453 "Von Willebrand factor C domain containing 2 like" B2RUY7 2 214411054-214578976 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 2.7;retina: 1.4" "Group enriched" "Detected in some" 21 "Excitatory neurons: 67.4;Inhibitory neurons: 132.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044815, HPA059414" Uncertain "Secreted - unknown location" NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044815: AB_10962359, HPA059414: AB_2684007" "unprognostic (8.77e-2)" "unprognostic (2.83e-3)" "unprognostic (2.05e-2)" "unprognostic (8.49e-2)" "unprognostic (1.51e-3)" "unprognostic (4.36e-1)" "unprognostic (2.56e-2)" "unprognostic (2.05e-1)" "unprognostic (3.89e-1)" 0.0 0.0 2.1 0.0 1.7 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.2 0.0 0.0 0.0 0.0 0.8 1.8 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.7 0.1 2.1 2.7 2.2 0.8 1.8 1.8 0.2 2.3 1.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 67.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 132.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 4.5 2.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.3;ovary: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Cone photoreceptor cells: 29.2;Hepatocytes: 16.4;Rod photoreceptor cells: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.2;Hep G2: 26.3;HSkMC: 13.4;REH: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Vesicles, Cytosol" "HPA040401: AB_2676963, HPA043921: AB_2678731" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-3)" "unprognostic (9.27e-4)" "unprognostic (1.21e-2)" "unprognostic (4.01e-4)" "unprognostic (3.04e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-4)" "unprognostic (7.20e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-1)" 2.8 1.1 0.6 0.1 0.9 1.6 1.5 0.3 1.6 2.9 0.0 0.6 0.3 1.3 0.6 0.9 3.5 0.6 0.8 0.7 0.7 0.5 14.3 0.3 0.2 0.5 1.2 7.9 0.3 0.1 0.6 2.4 0.4 1.0 0.4 0.8 0.9 0.5 0.7 0.7 0.4 0.4 0.0 0.4 0.4 1.8 0.5 2.5 0.8 0.4 0.1 0.6 1.2 0.2 0.0 0.1 1.5 0.2 0.2 1.8 0.6 0.2 2.0 0.0 0.3 7.2 0.0 0.5 0.0 0.4 0.1 0.0 2.3 0.0 0.1 0.4 0.0 0.8 0.0 26.3 1.2 0.0 0.3 13.4 0.6 0.7 0.0 0.1 2.3 3.3 0.2 0.3 0.3 0.1 5.5 0.0 2.2 0.0 0.0 14.0 0.2 0.0 0.1 0.1 0.6 1.0 0.0 0.1 0.7 2.4 0.9 0.0 0.8 0.3 0.3 0.5 0.2 0.2 0.6 1.2 0.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.3 1.6 0.7 0.7 0.5 1.2 0.4 0.0 0.5 0.2 2.1 3.2 1.7 19.2 0.3 1.8 1.8 3.8 3.4 3.6 1.7 0.5 1.0 1.5 2.3 0.0 29.2 1.0 0.5 0.2 0.0 0.1 0.5 2.9 1.0 5.5 1.8 6.1 7.5 0.5 5.0 2.6 0.0 1.8 3.8 6.5 2.5 16.4 1.2 0.0 5.8 0.1 2.0 3.5 2.4 0.8 6.8 2.6 1.8 2.8 2.3 2.3 1.0 2.5 1.4 0.0 0.0 1.9 0.4 1.1 0.1 0.3 5.4 21.1 0.0 0.9 1.1 1.1 3.4 1.3 2.3 4.4 0.9 7.7 0.3 0.7 VWDE FLJ14712 ENSG00000146530 "Von Willebrand factor D and EGF domains" Q8N2E2 7 12330885-12403941 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.3;salivary gland: 3.3;thyroid gland: 3.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.8;Excitatory neurons: 11.8;Granulosa cells: 5.4;Inhibitory neurons: 11.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 5.0;K-562: 13.0;NTERA-2: 4.8;SCLC-21H: 7.0" "Low region specificity" "Detected in many" "HPA026619, HPA036044, HPA036045" Uncertain Approved Cytosol "Secreted - unknown location" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA026619: AB_2671920, HPA036044: AB_2674916, HPA036045: " "unprognostic (6.39e-2)" "unprognostic (1.65e-3)" "unprognostic (5.36e-3)" "unprognostic (1.78e-4)" "unprognostic (1.39e-2)" "unprognostic (4.19e-3)" "unprognostic (2.38e-1)" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (6.25e-2)" "unprognostic (1.68e-1)" "unprognostic (6.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-3)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.73e-1)" 0.0 0.3 0.5 0.1 0.8 2.3 1.6 0.0 0.5 0.1 0.0 0.3 0.1 0.4 4.3 0.1 1.1 0.4 2.0 0.4 0.3 0.2 0.1 0.2 0.1 0.4 0.4 0.0 0.0 0.3 0.4 0.1 0.3 1.1 0.1 0.0 3.3 1.6 0.0 0.4 0.1 0.1 0.5 0.1 0.7 0.2 0.3 0.1 3.1 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.0 1.2 0.0 0.2 2.4 0.0 1.5 0.5 0.7 0.3 2.4 0.1 0.0 0.0 0.9 0.7 1.7 1.6 1.1 2.7 2.4 3.4 5.0 0.0 0.0 1.9 1.5 0.1 0.2 0.0 1.1 2.4 1.0 1.3 13.0 0.0 0.0 1.6 0.0 0.0 4.8 0.0 0.8 0.0 0.0 1.1 0.4 1.2 7.0 1.5 0.0 1.4 0.0 1.7 0.0 0.8 0.1 0.0 0.9 0.0 1.5 2.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.8 0.0 0.5 0.4 0.3 0.4 0.4 0.3 0.5 0.3 0.1 0.1 0.0 1.5 0.3 0.0 0.3 2.1 0.9 2.8 0.0 1.6 1.0 8.8 0.0 1.2 0.0 0.0 0.3 0.0 0.2 0.0 0.1 1.2 0.7 0.2 0.2 0.0 3.0 11.8 0.0 0.5 1.1 0.0 1.8 0.0 5.4 0.0 0.0 0.1 0.0 11.6 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 1.2 0.0 0.0 2.9 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.4 0.4 0.7 0.1 0.1 0.7 0.4 0.5 1.8 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WDR25 "C14orf67, MGC4645" ENSG00000176473 "WD repeat domain 25" Q64LD2 14 100376418-100530303 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003113 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA003113: AB_2215263" "unprognostic (5.31e-2)" "unprognostic (5.76e-3)" "unprognostic (2.28e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.36e-4)" "unprognostic (1.79e-2)" "unprognostic (6.62e-2)" "unprognostic (3.94e-3)" "unprognostic (2.44e-2)" "unprognostic (1.37e-2)" "prognostic favorable (3.89e-5)" "unprognostic (1.01e-2)" "unprognostic (1.73e-1)" "unprognostic (7.30e-2)" "unprognostic (7.51e-2)" 6.4 10.0 7.6 2.5 7.8 4.1 6.5 8.0 9.5 8.1 8.1 6.7 3.2 7.9 4.2 4.5 6.8 3.0 6.6 7.4 7.5 7.0 8.6 5.8 3.6 7.6 7.6 6.6 12.9 3.5 11.3 3.3 8.5 7.9 2.5 4.5 5.7 3.6 10.7 5.7 4.8 2.7 7.0 5.7 6.5 7.4 7.3 5.6 9.1 4.5 2.3 7.9 5.4 7.8 3.5 6.1 4.2 15.6 6.7 6.2 3.5 6.4 10.2 7.3 7.4 2.9 6.5 5.1 7.9 5.0 2.0 6.2 4.0 7.8 3.8 5.0 2.9 3.4 6.9 4.9 12.2 4.0 3.8 9.3 9.2 5.3 7.9 6.4 5.3 5.9 4.2 7.3 4.8 13.5 6.0 4.4 3.2 4.2 10.7 4.3 5.9 3.6 5.6 2.8 9.8 10.3 5.2 1.9 9.0 4.0 7.2 1.4 9.2 2.8 3.2 10.8 3.7 4.9 2.6 2.5 9.7 3.0 5.4 34.0 16.4 24.6 8.6 14.6 8.7 13.0 11.1 9.1 14.3 8.5 11.7 8.6 8.7 5.6 16.3 11.0 12.0 12.2 7.6 7.8 8.0 9.5 7.4 7.5 7.6 7.6 8.5 7.0 7.3 7.8 7.1 0.0 6.4 12.1 5.1 3.2 4.3 8.6 0.6 8.8 5.5 6.1 2.6 0.0 6.9 3.7 10.4 8.4 6.7 6.3 9.8 12.7 9.2 13.8 6.7 8.8 5.4 11.0 17.8 33.6 4.7 6.2 8.2 8.5 3.8 3.9 5.0 8.7 6.9 5.0 16.9 9.0 14.2 5.6 4.0 6.3 6.8 3.7 5.4 16.9 5.4 14.0 5.2 14.6 19.1 13.3 3.8 11.3 6.3 3.3 7.5 17.9 11.8 16.2 13.1 4.5 7.2 15.6 17.0 2.8 3.0 7.0 5.0 9.2 7.1 3.0 WFDC1 PS20 ENSG00000103175 "WAP four-disulfide core domain 1" Q9HC57 16 84294846-84329844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 99.8;seminal vesicle: 115.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.1;Fibroblasts: 72.6;Peritubular cells: 257.3;Smooth muscle cells: 95.8;Theca cells: 325.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 29.8;BJ: 20.5;HEL: 18.2;HeLa: 27.6;THP-1: 9.9;U-937: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031411 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA031411: AB_10600921" "unprognostic (6.53e-2)" "unprognostic (1.27e-1)" "unprognostic (1.61e-2)" "unprognostic (8.66e-4)" "unprognostic (1.41e-2)" "unprognostic (1.50e-3)" "unprognostic (1.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.78e-2)" "unprognostic (5.49e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (3.04e-1)" 8.1 26.9 16.5 10.5 16.5 1.9 4.3 19.1 21.2 21.5 12.9 79.3 8.9 17.3 18.8 24.5 7.9 35.1 4.4 16.1 15.5 16.7 5.5 29.5 0.6 17.0 16.2 3.7 1.0 0.4 5.7 99.8 15.3 69.0 17.4 8.4 6.2 115.1 1.2 3.2 14.6 32.2 14.9 3.5 20.8 12.5 16.3 0.3 4.8 1.6 0.8 54.2 13.5 14.9 0.0 0.0 4.4 29.8 0.0 0.1 0.2 20.5 2.5 0.0 0.0 0.0 0.0 0.0 5.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 27.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.5 0.0 0.4 0.0 0.0 2.3 0.0 0.0 5.3 0.1 0.0 0.5 3.2 0.1 0.1 9.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 16.5 19.1 21.2 16.1 15.5 17.0 16.2 15.3 14.9 16.3 14.9 3.4 3.2 0.5 9.1 0.0 1.8 0.9 0.1 0.0 111.1 2.0 0.9 1.4 0.0 0.1 1.8 0.0 2.1 0.1 0.9 11.7 0.0 27.8 0.6 10.6 3.9 4.2 0.0 4.1 0.0 2.0 72.6 7.7 0.5 0.0 0.2 12.5 0.0 6.6 5.0 0.9 4.7 0.0 0.0 3.0 41.1 15.8 2.3 0.0 2.8 0.0 1.4 0.0 29.1 0.6 0.1 0.6 257.3 0.3 1.3 0.4 1.3 0.7 4.2 0.0 1.0 95.8 5.5 0.9 0.1 0.4 3.8 0.5 325.9 3.1 1.0 WFDC10A "C20orf146, dJ688G8.3, WAP10" ENSG00000180305 "WAP four-disulfide core domain 10A" Q9H1F0 20 45629739-45631196 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 439 "epididymis: 288.1" "Cell type enhanced" "Detected in some" "Early spermatids: 1.1;granulocytes: 4.5;Late spermatids: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 288.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WFDC10B WAP12 ENSG00000182931 "WAP four-disulfide core domain 10B" Q8IUB3 20 45684653-45705019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 27.3;retina: 11.7" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Early spermatids: 5.5;Late spermatids: 10.1;Microglial cells: 3.7;Rod photoreceptor cells: 9.6;Spermatocytes: 4.8" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "PC-3: 1.9" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.14e-1)" "unprognostic (2.31e-1)" "unprognostic (1.37e-4)" "unprognostic (1.60e-1)" "unprognostic (2.69e-1)" "unprognostic (4.81e-2)" "unprognostic (4.30e-3)" "unprognostic (5.64e-2)" "unprognostic (1.14e-2)" "unprognostic (3.36e-1)" "unprognostic (0.00e+0)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" "unprognostic (2.21e-2)" "unprognostic (3.17e-1)" 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.2 0.6 0.4 0.2 0.6 0.0 0.3 27.3 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.0 0.7 0.0 0.5 0.6 0.1 0.0 0.0 0.1 0.4 0.3 0.7 0.5 11.7 0.0 0.2 0.0 1.2 0.2 0.4 0.4 0.0 0.3 4.3 0.2 0.2 0.0 0.0 0.0 5.9 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.6 1.9 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.2 0.1 0.5 0.6 0.3 0.4 0.2 0.3 0.0 0.0 0.5 3.6 0.0 0.0 0.1 0.4 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.3 0.0 0.1 0.0 0.0 1.3 0.4 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.4 2.0 0.0 0.0 10.1 0.0 0.0 0.0 3.7 0.0 0.9 0.0 1.5 0.9 1.2 0.1 0.0 0.0 0.4 0.3 0.0 0.0 9.6 0.0 0.0 0.1 4.8 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.7 WFDC11 WAP11 ENSG00000180083 "WAP four-disulfide core domain 11" Q8NEX6 20 45648563-45670270 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 18 "epididymis: 93.8" "Cell type enriched" "Detected in some" 12 "Early spermatids: 55.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "basophil: 2.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.3" "Group enriched" "Detected in some" 5 "HeLa: 8.7;RPMI-8226: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.4 0.8 0.2 0.5 2.9 0.3 2.9 2.4 0.1 0.8 0.2 0.0 0.2 93.8 0.2 0.2 0.5 0.1 0.4 0.5 0.2 0.3 0.1 0.2 0.5 0.1 0.2 0.2 0.1 0.0 0.2 0.6 0.4 0.0 2.0 0.6 0.1 0.1 1.5 0.2 0.1 0.0 0.2 0.3 5.0 0.4 0.0 0.3 0.0 0.1 0.2 0.0 3.0 0.1 0.7 0.0 0.1 0.4 0.5 0.8 0.7 0.1 0.0 0.0 0.5 0.2 0.4 0.2 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.5 0.8 8.7 0.5 0.0 0.4 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.4 0.1 0.0 0.1 0.3 0.7 0.7 0.2 0.4 0.1 0.3 5.3 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.7 0.0 0.1 0.4 0.2 0.1 0.3 0.3 0.0 0.0 1.4 0.2 2.3 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.3 0.3 0.0 0.2 0.0 0.0 0.8 0.5 2.9 2.4 0.4 0.5 0.5 0.1 0.6 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.8 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 WFDC12 "C20orf122, dJ211D12.4, WAP2" ENSG00000168703 "WAP four-disulfide core domain 12" Q8WWY7 20 45123425-45124465 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 42.0" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 2.6;Collecting duct cells: 5.5" "Group enriched" "Detected in many" 7 "head and neck cancer: 18.9;melanoma: 14.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 86000 "Cluster 31: Skin - Epidermis development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "unprognostic (1.18e-2)" "unprognostic (5.42e-2)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (3.40e-3)" "unprognostic (1.72e-2)" "unprognostic (8.70e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (4.49e-2)" "unprognostic (3.91e-1)" "unprognostic (5.50e-3)" 0.1 0.1 1.2 0.1 0.7 1.0 2.5 0.2 1.1 0.8 0.4 0.2 0.5 0.2 1.8 6.7 0.1 0.2 0.0 1.0 0.2 0.3 0.2 1.1 0.2 0.3 0.2 0.2 0.0 0.1 0.0 0.1 0.6 1.8 0.2 0.7 2.1 2.9 0.6 42.0 0.2 0.2 0.0 0.2 0.1 1.7 0.7 1.2 0.3 0.0 1.5 0.1 9.8 0.5 0.2 0.1 0.0 0.1 0.9 0.1 0.3 0.1 0.4 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.6 0.4 0.0 0.0 0.3 0.3 0.3 0.0 0.3 0.0 0.0 0.3 0.2 0.4 0.3 0.1 0.2 0.3 0.3 0.1 0.1 0.3 0.4 0.4 0.1 0.0 0.5 0.1 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.1 0.3 0.3 0.3 0.3 0.3 0.2 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.2 1.1 1.0 0.2 0.3 0.2 0.6 0.0 0.7 0.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.5 5.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 WFDC13 "C20orf138, dJ601O1.3, WAP13" ENSG00000168634 "WAP four-disulfide core domain 13" Q8IUB5 20 45702038-45708817 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "epididymis: 89.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Rod photoreceptor cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (2.53e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-3)" "unprognostic (7.96e-3)" "unprognostic (2.04e-1)" "unprognostic (1.02e-11)" "unprognostic (1.17e-1)" "unprognostic (1.44e-2)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 89.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 WFDC2 "dJ461P17.6, EDDM4, HE4, WAP5" ENSG00000101443 "WAP four-disulfide core domain 2" Q14508 20 45469753-45481532 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartic protease inhibitor, Protease inhibitor, Serine protease inhibitor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 5211.9;salivary gland: 1988.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4507.8;Club cells: 6299.8;Collecting duct cells: 1988.1;Endometrial ciliated cells: 3253.3;Glandular and luminal cells: 4817.5;Respiratory ciliated cells: 2935.3;Urothelial cells: 3783.3" "Group enriched" "Detected in all" 4 "endometrial cancer: 1815.6;ovarian cancer: 1086.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "A-431: 115.8;CAPAN-2: 210.6;EFO-21: 171.3;HaCaT: 151.9;RPTEC TERT1: 165.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042302 Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA042302: AB_2677939" "unprognostic (5.75e-2)" "unprognostic (2.23e-1)" "unprognostic (4.37e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (7.19e-3)" "unprognostic (1.94e-1)" "unprognostic (5.49e-3)" "unprognostic (3.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.42e-1)" "unprognostic (1.40e-1)" "prognostic favorable (4.44e-5)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" "unprognostic (3.20e-2)" 16.8 1.6 6.7 11.0 14.1 0.0 81.2 6.6 9.3 5211.9 22.3 163.7 9.6 240.0 941.9 54.9 676.7 166.1 6.0 7.2 7.5 909.9 23.6 144.7 0.9 7.7 9.1 10.4 30.5 81.9 152.4 0.7 7.1 221.7 224.9 6.9 1988.3 825.3 2.0 38.2 60.1 28.9 6.9 0.7 44.1 14.9 7.2 12.3 253.8 0.5 8.8 161.2 25.0 7.3 115.8 0.0 0.3 0.4 0.0 0.1 4.7 0.0 0.0 0.0 0.0 4.9 210.6 0.0 171.3 0.0 0.7 151.9 0.0 0.0 0.0 0.8 1.9 0.0 1.2 0.3 0.0 0.2 0.7 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 6.7 0.3 2.7 18.4 0.6 0.0 0.1 0.0 0.0 165.6 1.3 5.0 1.0 10.6 0.0 1.1 2.0 3.1 0.6 0.0 0.3 2.8 0.6 0.5 0.7 0.6 1.6 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.7 14.1 6.6 9.3 7.2 7.5 7.7 9.1 7.1 6.9 7.2 7.3 2.8 169.9 273.8 2.6 4.2 8.9 1190.9 4507.8 35.3 30.3 340.4 238.5 2.0 94.4 6299.8 1988.1 22.9 1.0 4.3 239.8 221.1 308.2 1.6 3253.3 359.3 21.7 422.7 0.0 4.7 129.2 0.8 23.4 31.6 4817.5 10.1 12.5 3.9 3.3 1.9 0.0 7.6 1764.7 1328.5 0.6 1.1 5.0 36.1 26.8 10.6 1.9 5.7 31.3 0.0 2.0 3.4 179.0 424.6 0.0 0.8 1169.7 1.7 113.9 2935.3 6.1 6.6 1.1 319.1 12.4 11.9 110.2 14.1 0.7 36.8 0.0 318.2 3783.3 WFDC3 "dJ447F3.3, WAP14" ENSG00000124116 "WAP four-disulfide core domain 3" Q8IUB2 20 45747944-45791932 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 16.7;testis: 20.0" "Group enriched" "Detected in many" 5 "Early spermatids: 115.9;Late spermatids: 222.8;Spermatocytes: 108.1" "Cancer enhanced" "Detected in many" "lung cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "PC-3: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-1)" "unprognostic (5.75e-2)" "unprognostic (9.30e-4)" "unprognostic (6.63e-3)" "unprognostic (4.02e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-3)" "unprognostic (1.79e-1)" "unprognostic (1.36e-8)" "unprognostic (8.53e-2)" "unprognostic (2.45e-1)" "unprognostic (5.27e-3)" "unprognostic (3.03e-2)" 0.3 0.0 0.5 0.1 0.6 0.0 1.2 0.6 0.5 0.0 0.4 0.2 0.3 0.1 0.8 0.0 0.6 0.0 0.0 0.5 0.5 0.2 0.0 0.1 0.0 0.6 0.9 0.0 0.1 0.0 0.1 0.0 0.6 0.1 0.1 0.3 0.0 0.2 0.0 16.7 0.0 0.9 0.8 0.0 0.0 20.0 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.6 0.5 0.5 0.5 0.6 0.9 0.6 0.8 0.6 0.6 0.5 0.0 2.6 0.7 0.1 1.1 5.9 2.7 0.0 1.2 2.4 1.8 0.8 0.0 12.3 3.7 6.2 0.4 0.0 5.7 11.7 2.5 115.9 17.6 0.7 0.2 3.6 0.0 0.6 10.0 1.8 2.1 3.1 3.4 1.3 1.7 2.9 0.9 1.1 0.0 0.6 12.1 24.4 0.6 0.8 222.8 1.5 1.3 0.0 0.0 0.3 2.2 0.0 1.0 0.8 13.1 2.0 2.6 0.0 6.2 5.8 5.9 9.0 28.7 0.0 0.5 1.5 108.1 2.6 1.5 3.1 0.0 0.4 0.4 1.1 14.3 WFDC5 "dJ211D12.5, WAP1" ENSG00000175121 "WAP four-disulfide core domain 5" Q8TCV5 20 45109452-45115172 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 393.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 55.8;Early spermatids: 17.6;Late spermatids: 10.4;Suprabasal keratinocytes: 43.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.32e-1)" "unprognostic (3.22e-2)" "unprognostic (3.05e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.32e-5)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.96e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.1 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.6 1.5 1.2 393.9 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.6 0.0 0.0 13.3 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 55.8 0.4 2.5 0.6 0.0 0.1 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.1 0.0 0.0 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 10.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 3.0 43.2 0.0 0.1 0.0 0.1 0.2 WFDC6 "C20orf171, dJ461P17.11, WAP6" ENSG00000243543 "WAP four-disulfide core domain 6" Q9BQY6 20 45534196-45539482 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 250.9" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 34.2" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.9;testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-87 MG: 2.6" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.68e-3)" "unprognostic (2.21e-3)" "unprognostic (1.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.91e-2)" 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.4 1.0 0.0 0.0 0.0 0.2 250.9 0.1 7.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.5 0.1 0.0 0.0 0.0 0.0 37.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 34.2 0.0 0.0 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 WFDC8 "C20orf170, dJ461P17.1, WAP8" ENSG00000158901 "WAP four-disulfide core domain 8" Q8IUA0 20 45551153-45579326 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 518 "epididymis: 410.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-87 MG: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042710, HPA071119" Enhanced "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "HPA042710: AB_2732501, HPA071119: AB_2732172" "unprognostic (5.63e-3)" "unprognostic (1.09e-2)" "unprognostic (2.34e-1)" "unprognostic (9.96e-2)" "unprognostic (1.07e-2)" 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 410.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 WFDC9 "dJ688G8.2, WAP9" ENSG00000180205 "WAP four-disulfide core domain 9" Q8NEX5 20 45607939-45631284 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 464 "epididymis: 989.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 989.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WFIKKN1 "C16orf12, RJD2, WFDC20A, WFIKKN" ENSG00000127578 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1" Q96NZ8 16 629239-634117 "Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.3" "Cell type enhanced" "Detected in some" "Astrocytes: 4.9;Horizontal cells: 10.1;Melanocytes: 3.6" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 4.4;Hep G2: 1.0;NTERA-2: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (3.12e-1)" "unprognostic (2.57e-1)" "unprognostic (3.17e-2)" "unprognostic (1.59e-2)" "unprognostic (3.55e-1)" "unprognostic (2.28e-2)" "unprognostic (3.36e-2)" "unprognostic (4.45e-2)" "unprognostic (8.53e-2)" "unprognostic (2.43e-1)" "unprognostic (3.78e-3)" "unprognostic (1.19e-1)" "unprognostic (5.56e-3)" "unprognostic (1.53e-1)" "unprognostic (3.02e-1)" "unprognostic (2.50e-3)" "unprognostic (4.70e-5)" 0.2 0.1 0.3 0.0 0.4 0.0 0.1 1.5 0.8 0.4 0.0 0.3 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.3 0.0 2.3 0.8 0.4 0.0 0.2 0.0 0.6 1.1 0.0 1.2 0.0 0.1 0.8 0.0 0.0 0.3 0.0 0.5 1.0 0.3 0.0 0.0 0.6 0.5 1.0 0.1 0.0 0.5 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.5 0.8 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.5 0.4 0.0 0.5 4.9 0.1 0.9 0.2 0.5 0.6 2.9 0.7 0.8 0.8 0.0 0.3 0.0 0.0 0.2 0.2 2.2 0.0 0.0 0.1 1.3 1.9 0.9 1.2 0.0 1.4 0.2 0.1 0.3 0.0 1.8 1.3 1.4 0.7 0.9 0.1 10.1 0.5 1.4 0.0 0.6 0.0 0.1 0.0 0.2 3.6 1.0 0.0 1.1 0.0 1.0 1.1 0.7 2.4 0.7 0.0 0.7 2.1 0.4 1.4 0.1 0.0 0.7 0.4 1.6 0.7 1.4 1.6 0.3 0.2 0.3 1.4 0.3 WFIKKN2 "WFDC20B, WFIKKNRP" ENSG00000173714 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2" Q8TEU8 17 50834650-50842353 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "choroid plexus: 578.0;ovary: 146.2" "Group enriched" "Detected in some" 11 "Leydig cells: 9.0;Peritubular cells: 24.0" "Group enriched" "Detected in some" 5 "glioma: 0.7;testis cancer: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "medulla oblongata: 12.6;midbrain: 5.1;thalamus: 6.1" "Secreted in other tissues" NA NA 4500000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" "unprognostic (7.31e-2)" "unprognostic (7.31e-2)" "unprognostic (1.31e-2)" "unprognostic (4.80e-2)" "unprognostic (3.46e-2)" "unprognostic (5.72e-2)" "unprognostic (5.42e-3)" "unprognostic (2.54e-3)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (2.19e-1)" "unprognostic (4.08e-3)" "unprognostic (1.42e-3)" "unprognostic (2.17e-1)" "unprognostic (2.75e-2)" "unprognostic (1.14e-1)" 0.1 1.3 2.6 0.0 1.7 0.0 0.1 5.3 1.7 0.3 578.0 1.0 0.0 1.1 0.5 0.2 0.8 0.2 0.7 8.7 0.8 0.1 0.0 0.2 0.0 1.4 1.1 146.2 0.3 0.0 2.2 0.0 1.5 0.4 0.0 0.3 0.1 0.6 2.1 0.9 0.2 0.3 0.8 0.0 0.2 2.4 6.5 0.5 0.0 0.9 0.0 0.1 0.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 5.3 1.7 8.7 0.8 1.4 1.1 1.5 0.8 6.5 1.8 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 9.0 0.1 0.0 0.0 0.0 1.5 0.0 0.5 0.1 0.0 0.0 24.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2736.1" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.2;LHCN-M2: 1.0;NTERA-2: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" 1.3 2.7 22.4 0.3 34.3 0.0 22.9 16.3 44.6 1.6 15.0 0.3 0.0 8.6 23.8 4.7 1.5 0.0 0.5 24.8 35.4 0.7 0.0 117.4 0.1 16.6 16.5 1.2 0.3 0.0 46.5 0.0 16.2 14.2 0.3 599.7 45.1 2.8 0.1 6.6 2.2 0.9 16.5 0.1 1.4 0.7 23.4 0.2 0.0 0.7 0.0 1.7 2.2 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 34.3 16.3 44.6 24.8 35.4 16.6 16.5 16.2 16.5 23.4 18.4 0.0 35.3 197.8 186.1 0.0 12.6 34.5 0.0 2.2 25.0 0.7 13.7 1.6 0.0 26.6 1.8 8.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 4.7 0.0 0.0 0.6 0.0 0.0 27.8 0.5 0.1 7.6 1.0 0.0 0.0 0.0 15.2 46.5 0.0 0.0 0.0 20.4 0.0 0.0 0.8 23.2 12.2 0.0 2736.1 0.0 1.5 0.9 0.0 0.0 0.4 0.2 25.5 0.0 1.2 34.2 80.8 0.0 1.8 1.5 2.5 2.0 0.4 10.5 0.0 1.2 0.0 0.0 0.8 WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 4.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.1;Gastric mucus-secreting cells: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 4.5;cerebral cortex: 2.1" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 29 "T-cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" 0.0 0.0 0.8 0.5 4.5 1.1 0.0 0.0 2.1 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.7 0.2 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.3 0.7 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 5.1 0.1 2.0 2.9 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.2 0.5 0.8 4.5 0.0 2.1 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 WNT10A ENSG00000135925 "Wnt family member 10A" Q9GZT5 2 218880852-218899581 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant, Ectodermal dysplasia, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 7.0;skin 1: 8.9" "Cell type enhanced" "Detected in many" "B-cells: 12.2;Basal keratinocytes: 17.1;Basal respiratory cells: 15.5;Basal squamous epithelial cells: 30.1;Bipolar cells: 16.2;dendritic cells: 16.4;Plasma cells: 30.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 6.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 6.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 50.8;HaCaT: 140.1;HDLM-2: 58.7;RPTEC TERT1: 29.2;U-266/70: 69.0" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Region enhanced" "Detected in single" "basal ganglia: 2.1" HPA013898 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "HPA013898: AB_1858847" "unprognostic (2.99e-4)" "unprognostic (4.31e-2)" "unprognostic (8.55e-2)" "unprognostic (1.17e-3)" "unprognostic (2.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.23e-3)" "unprognostic (9.52e-2)" "unprognostic (6.64e-9)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (4.89e-3)" "unprognostic (1.82e-1)" 0.7 0.2 0.7 1.0 1.6 0.5 0.5 0.2 1.3 1.5 0.2 1.6 3.7 0.0 0.4 7.0 1.2 0.3 0.1 1.2 0.5 2.4 0.2 0.7 2.5 0.4 0.6 0.2 0.1 0.0 4.3 3.4 0.5 1.7 1.0 1.4 2.5 1.0 0.0 8.9 2.1 0.0 0.3 2.0 2.5 0.4 0.7 1.1 0.2 0.0 1.9 2.7 2.9 0.7 15.8 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 50.8 2.8 10.4 0.0 3.8 140.1 0.0 0.1 0.0 58.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 10.5 29.2 0.4 0.0 0.4 0.3 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 69.0 1.1 1.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 6.2 1.0 0.0 0.7 1.6 0.2 1.3 1.2 0.5 0.4 0.6 0.5 0.3 0.7 0.7 0.2 0.0 0.0 0.3 12.2 17.1 8.2 15.5 30.1 16.2 0.5 1.3 1.4 0.0 1.1 9.2 2.1 1.2 16.4 0.0 0.0 0.3 1.2 0.3 0.1 0.2 0.0 0.4 1.3 0.0 0.4 1.9 0.5 0.2 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.0 2.0 0.0 1.3 0.1 0.6 1.0 7.2 0.0 0.0 0.5 0.0 0.5 0.1 0.1 0.0 0.0 30.4 2.5 0.0 0.3 0.6 1.5 0.0 0.1 0.8 0.9 0.6 5.2 4.7 0.1 9.8 0.0 0.2 3.2 WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.3;Extravillous trophoblasts: 21.7;Fibroblasts: 4.8;Inhibitory neurons: 4.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 7.3;T-47d: 8.2;U-266/84: 7.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA055048, HPA062539" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA055048: AB_2682683, HPA062539: AB_2684793" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" 1.5 0.2 13.1 1.5 14.9 1.2 0.6 4.2 17.9 0.8 3.2 1.4 1.4 0.3 1.5 1.4 1.0 0.5 1.5 15.3 7.3 0.4 0.4 1.1 1.7 8.6 7.6 0.2 0.3 0.1 2.4 0.3 8.2 0.8 0.7 0.1 0.9 0.6 0.7 3.4 4.3 0.1 5.1 4.1 1.1 3.3 10.4 1.9 1.0 0.4 1.5 1.3 1.0 9.8 1.9 1.2 0.0 1.7 0.0 0.0 4.6 1.3 2.4 0.5 0.1 3.6 4.0 0.0 0.3 0.2 1.5 2.2 4.8 0.3 0.2 1.1 6.3 2.1 1.7 0.1 0.0 0.7 2.9 0.0 0.4 0.1 2.1 4.1 0.0 1.5 7.3 0.3 0.7 2.4 0.1 2.5 0.0 1.3 2.5 0.0 0.6 2.2 0.0 0.4 0.1 0.0 0.3 0.1 0.6 2.2 8.2 2.7 0.0 2.5 4.9 0.4 0.6 2.6 7.8 0.0 1.0 5.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.9 4.2 17.9 15.3 7.3 8.6 7.6 8.2 5.1 10.4 9.8 0.2 0.0 0.0 0.7 0.2 0.4 0.0 0.0 1.8 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.8 0.2 0.1 0.0 0.0 0.0 7.3 0.0 21.7 4.8 0.0 0.1 0.0 0.0 0.7 0.0 0.3 0.0 4.7 0.2 0.0 0.0 1.2 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.7 3.0 0.9 1.3 1.4 1.6 0.0 0.0 0.1 WNT11 ENSG00000085741 "Wnt family member 11" O96014 11 76186325-76210736 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.4" "Group enriched" "Detected in some" 5 "Adipocytes: 41.5;Fibroblasts: 23.2;Theca cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 6 "NK-cells: 2.9" "Cell line enhanced" "Detected in some" "BEWO: 36.2;CACO-2: 12.1;CAPAN-2: 17.8;EFO-21: 57.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA050101 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA050101: AB_2681015" "prognostic favorable (5.97e-4)" "unprognostic (9.27e-2)" "unprognostic (2.01e-2)" "unprognostic (2.52e-1)" "unprognostic (1.87e-2)" "unprognostic (8.43e-2)" "unprognostic (7.88e-2)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (2.88e-2)" "unprognostic (4.36e-2)" "unprognostic (3.10e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (3.16e-3)" "unprognostic (1.09e-3)" 37.4 20.8 1.7 0.4 3.5 0.9 23.7 4.1 2.2 4.8 14.3 3.6 2.5 2.7 1.3 1.2 6.7 2.1 8.3 3.8 3.5 2.8 8.0 6.3 1.1 7.4 2.7 4.5 9.5 1.2 3.1 4.1 6.9 4.3 1.1 0.3 4.3 1.1 12.3 8.1 3.3 0.6 2.8 3.5 1.4 0.9 2.8 0.9 17.2 7.1 0.2 4.0 3.8 2.1 0.0 0.0 0.0 0.0 2.9 0.2 36.2 0.0 0.0 0.1 0.2 12.1 17.8 0.0 57.0 0.1 0.2 5.5 1.1 0.0 0.0 5.5 2.1 2.9 1.4 2.2 0.0 0.0 0.4 0.1 1.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 1.4 0.3 0.0 0.4 0.9 0.0 2.9 0.4 0.0 2.1 0.2 0.0 2.5 0.1 1.4 0.0 0.0 2.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.2 1.7 3.5 4.1 2.2 3.8 3.5 7.4 2.7 6.9 2.8 2.8 2.1 41.5 0.0 0.0 0.3 0.5 1.3 0.5 0.0 1.2 0.0 0.9 1.9 4.7 0.0 0.0 0.0 0.0 0.9 2.3 2.2 0.0 0.0 0.0 5.0 2.9 1.8 0.0 0.0 0.2 0.2 3.3 23.2 0.0 1.1 0.0 0.4 0.7 2.5 0.1 0.0 0.5 0.5 0.0 0.3 2.3 0.0 0.0 0.7 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 2.6 0.7 0.7 0.1 3.8 0.0 0.0 0.0 0.0 1.8 5.7 0.4 0.5 0.1 0.9 1.4 0.9 24.3 1.5 0.1 WNT16 ENSG00000002745 "Wnt family member 16" Q9UBV4 7 121325367-121341104 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 6.0;skin 1: 20.5" "Cell type enhanced" "Detected in some" "B-cells: 4.6;Basal keratinocytes: 10.1;Endometrial stromal cells: 3.6;Inhibitory neurons: 6.0;Microglial cells: 3.7;Plasma cells: 2.6;Suprabasal keratinocytes: 11.5" "Cancer enhanced" "Detected in some" "lung cancer: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 145 "memory B-cell: 15.6;naive B-cell: 15.4" "Lineage enriched" "Detected in single" 146 "B-cells: 15.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.3;HEK 293: 5.4;hTEC/SVTERT24-B: 1.6;U-2197: 2.6;U-266/70: 1.6" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "spinal cord: 4.4" "Secreted to extracellular matrix" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (6.53e-2)" "unprognostic (3.63e-2)" "unprognostic (7.24e-2)" "unprognostic (1.90e-2)" "unprognostic (2.94e-3)" "unprognostic (5.23e-2)" "unprognostic (1.77e-2)" "unprognostic (1.16e-1)" "unprognostic (1.12e-1)" "unprognostic (1.94e-1)" "unprognostic (3.77e-1)" "unprognostic (2.18e-2)" "unprognostic (3.57e-10)" "unprognostic (5.89e-3)" "unprognostic (2.73e-1)" "unprognostic (5.50e-2)" "unprognostic (1.66e-1)" 0.2 0.3 0.3 0.3 0.6 0.0 1.4 0.2 0.4 6.0 0.5 0.5 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.4 0.2 0.1 0.2 0.3 1.1 0.2 0.2 0.0 0.1 0.0 0.3 0.4 0.1 0.6 0.1 0.1 0.1 1.8 0.1 20.5 0.5 0.2 0.3 0.8 0.2 0.1 0.0 0.1 0.1 0.0 0.4 0.1 3.2 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.2 0.0 0.5 0.1 0.5 0.0 0.0 0.0 0.0 5.4 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.3 1.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.6 0.2 0.4 0.4 0.2 0.2 0.2 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 4.6 10.1 0.1 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 3.6 0.1 0.0 0.4 0.1 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 3.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 11.5 0.0 0.1 0.0 0.1 0.0 WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 39.9" "Cell type enhanced" "Detected in some" "Early spermatids: 30.9;Endometrial stromal cells: 33.1;Fibroblasts: 82.5;Late spermatids: 14.7;Spermatocytes: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 11.5" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA020920: AB_1858850" "unprognostic (1.90e-1)" "unprognostic (6.97e-2)" "unprognostic (2.88e-2)" "unprognostic (4.11e-3)" "unprognostic (9.14e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-2)" "unprognostic (2.75e-1)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.36e-2)" "unprognostic (1.41e-1)" "unprognostic (3.43e-1)" "unprognostic (4.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-1)" 1.2 0.0 0.2 0.1 0.4 0.0 0.8 0.1 0.7 3.5 0.3 0.1 0.0 8.6 0.1 0.0 0.8 0.2 0.4 0.4 0.3 0.1 0.5 6.9 0.0 0.1 0.5 0.3 0.1 0.0 0.1 39.9 0.1 3.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.1 0.1 0.9 0.0 0.5 1.5 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.7 0.4 0.3 0.1 0.5 0.1 0.1 1.5 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 1.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 30.9 0.8 33.1 9.8 0.0 0.0 1.4 0.0 3.6 82.5 0.0 0.6 0.0 0.0 10.8 0.6 7.7 0.0 0.5 0.0 0.0 0.8 0.3 14.7 1.5 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 13.6 0.5 0.0 2.7 9.0 0.2 0.0 0.0 0.2 WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 80.2;Peritubular cells: 197.5" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.4;HSkMC: 8.0;SuSa: 3.4;TIME: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA047274: AB_2732539, HPA066368: AB_2685664" "unprognostic (2.08e-3)" "unprognostic (2.06e-3)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (9.42e-2)" "unprognostic (4.90e-3)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (5.65e-4)" "unprognostic (5.41e-2)" "unprognostic (7.64e-2)" "unprognostic (4.80e-2)" "unprognostic (2.49e-2)" 4.5 1.9 2.0 1.5 4.9 0.1 2.8 2.1 2.8 8.2 2.0 5.6 3.0 4.9 2.8 5.8 4.7 2.8 4.3 1.9 1.7 2.4 1.0 6.3 0.8 1.8 1.7 10.9 1.8 0.6 2.3 4.8 1.9 6.1 5.3 5.5 2.2 13.9 1.6 11.1 5.2 2.2 1.4 1.7 3.8 3.8 1.8 0.2 1.9 0.8 0.7 5.6 9.1 2.3 0.4 0.3 2.2 0.5 2.2 4.4 0.4 1.0 1.0 0.2 0.4 0.2 0.5 1.1 0.2 1.1 0.2 1.4 0.7 0.3 0.2 0.0 0.4 0.1 0.8 0.3 1.8 0.2 0.5 8.0 0.8 0.4 0.1 1.3 1.2 0.3 0.1 0.2 0.2 0.3 0.1 0.1 0.3 0.0 0.3 0.1 0.3 0.0 1.5 0.3 0.3 0.3 0.7 0.1 0.7 3.4 0.0 0.2 3.5 0.3 1.4 0.8 0.3 0.1 0.1 0.0 0.9 0.1 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.0 4.9 2.1 2.8 1.9 1.7 1.8 1.7 1.9 1.4 1.8 2.3 7.6 12.8 3.3 2.0 2.0 10.1 1.8 6.1 5.2 14.1 2.1 0.9 6.5 1.5 3.9 1.8 27.1 2.1 2.4 3.5 0.0 0.8 5.6 2.6 3.6 10.2 8.4 2.1 5.5 1.4 0.8 17.7 1.1 6.8 2.5 2.8 6.1 0.2 1.1 5.0 6.2 2.2 4.1 2.1 8.2 3.4 80.2 4.0 3.6 30.9 2.2 9.8 0.0 11.6 7.1 2.0 4.8 197.5 2.5 4.4 2.9 0.9 4.6 27.6 0.0 9.7 2.7 5.9 5.5 26.4 13.9 1.9 1.9 2.0 1.5 2.6 WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.3;skin 1: 27.7" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.5;Early spermatids: 27.7;Late spermatids: 63.8;Suprabasal keratinocytes: 17.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;U-698: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" 0.8 0.4 1.3 0.4 1.1 0.1 1.0 0.7 1.0 1.0 0.2 0.6 3.4 0.5 0.0 1.3 0.5 0.1 0.9 0.8 1.2 1.7 12.3 0.9 0.2 1.4 1.8 0.5 0.8 2.5 1.7 0.2 1.2 1.3 0.2 0.2 1.2 0.0 0.2 27.7 2.7 0.2 0.7 0.7 0.4 4.4 4.4 0.1 1.3 0.0 0.1 0.4 1.1 0.7 3.9 1.7 8.5 0.0 0.1 0.1 0.7 0.8 0.9 3.0 0.0 2.7 1.7 1.6 2.3 2.1 6.1 1.3 0.4 0.0 3.9 0.0 0.4 0.0 3.0 2.3 0.0 0.1 0.1 0.2 1.8 1.1 2.3 3.5 1.1 2.5 1.5 0.0 1.0 1.7 0.0 1.4 0.0 1.0 2.4 2.9 1.9 0.2 0.6 0.0 0.1 0.7 1.6 0.0 1.2 2.1 0.0 4.0 0.2 3.2 2.1 0.4 1.5 0.6 0.2 14.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 1.1 0.7 1.0 0.8 1.2 1.4 1.8 1.2 0.7 4.4 0.7 0.2 0.0 1.5 3.9 0.5 44.5 0.6 0.6 3.4 1.1 3.0 1.7 1.3 1.5 0.4 0.0 0.0 2.2 0.1 0.7 1.9 0.7 27.7 0.1 0.7 0.5 0.0 0.0 5.4 2.5 0.1 1.1 0.0 0.2 0.0 0.7 0.4 4.0 0.2 8.4 4.3 0.6 0.0 0.0 1.5 63.8 0.3 0.1 1.8 1.0 0.6 0.2 0.0 4.0 1.1 2.9 1.4 0.4 0.0 1.2 3.7 0.5 0.3 0.8 0.0 1.4 1.1 0.9 2.9 0.8 17.6 0.3 0.0 0.3 0.9 0.3 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 40.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.1;Breast glandular cells: 19.9;Breast myoepithelial cells: 24.3;Endometrial stromal cells: 71.4;Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;SCLC-21H: 10.2;SK-BR-3: 8.6;T-47d: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" 0.8 9.0 2.4 0.4 1.5 0.3 2.2 0.2 2.9 8.9 0.5 2.3 3.2 4.5 8.9 12.1 8.3 2.6 0.1 2.0 2.9 1.1 1.4 1.2 0.1 1.6 1.8 16.8 3.0 0.1 5.6 1.6 1.2 5.5 1.6 0.2 4.1 2.6 3.1 40.8 3.1 1.9 1.1 0.3 4.3 0.6 3.9 1.1 3.4 0.6 1.5 3.1 6.3 1.1 1.3 0.1 2.5 0.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.3 8.5 0.0 0.6 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 1.1 0.2 0.3 0.0 0.0 0.0 1.6 10.2 0.0 0.1 8.6 0.6 0.6 3.4 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.5 0.2 2.9 2.0 2.9 1.6 1.8 1.2 1.1 3.9 1.1 0.9 3.2 8.6 0.3 0.7 16.7 4.3 42.1 6.8 0.0 19.9 24.3 0.6 0.0 15.2 0.0 0.0 0.7 0.1 0.9 0.0 2.7 0.1 4.1 71.4 0.6 29.4 0.0 0.2 0.6 0.1 3.1 0.5 1.6 0.0 0.2 0.7 0.5 0.1 0.0 1.9 16.0 4.1 0.0 0.2 0.9 0.0 0.4 5.4 6.5 0.1 0.0 0.0 0.0 0.3 0.9 0.1 3.8 0.6 5.7 0.3 0.0 12.0 0.0 0.0 0.4 2.2 0.0 0.3 2.5 10.4 0.3 0.6 0.0 0.6 4.2 WNT5A hWNT5A ENSG00000114251 "Wnt family member 5A" P41221 3 55465715-55490539 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 27.4;salivary gland: 34.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Basal squamous epithelial cells: 34.7;Club cells: 31.3;Endometrial stromal cells: 101.6;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 227.2;BJ hTERT+: 315.4;HeLa: 242.1;SiHa: 354.2;U-87 MG: 248.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.34e-3)" "unprognostic (1.35e-1)" "prognostic favorable (2.94e-5)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (1.14e-1)" "unprognostic (2.16e-2)" "unprognostic (3.91e-2)" "unprognostic (5.89e-2)" "unprognostic (9.58e-2)" "unprognostic (8.34e-3)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (9.70e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-3)" "unprognostic (3.63e-2)" 2.3 0.8 1.9 3.1 1.9 0.1 4.9 1.7 1.8 5.7 0.6 3.1 3.5 27.4 3.1 16.9 6.7 7.2 1.6 2.5 3.2 2.7 2.6 4.9 2.2 3.9 4.3 9.1 4.3 1.0 1.8 10.8 3.0 4.6 3.2 1.2 34.4 8.3 2.0 2.4 3.8 5.9 3.8 4.0 3.5 1.8 3.1 2.4 2.8 1.7 5.1 18.7 12.1 5.4 0.0 0.4 20.8 0.2 15.8 37.7 0.0 227.2 315.4 46.3 80.4 1.3 0.0 6.6 0.6 132.2 19.5 0.2 10.0 0.2 48.2 0.0 6.2 6.4 242.1 0.1 35.1 0.0 0.4 25.0 5.9 139.2 7.6 22.5 0.1 0.2 0.0 109.5 113.3 0.0 0.1 0.1 11.1 0.5 13.6 0.0 14.1 1.0 6.2 7.6 0.0 1.0 354.2 43.1 0.0 18.0 0.1 0.0 0.0 76.1 13.2 70.0 18.2 25.8 0.0 2.4 248.5 0.3 35.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 1.7 1.8 2.5 3.2 3.9 4.3 3.0 3.8 3.1 5.4 1.1 51.3 23.2 4.2 0.0 1.5 1.6 1.4 34.7 13.2 12.1 4.4 4.3 0.0 31.3 12.9 0.0 3.0 0.0 0.2 0.0 0.2 15.8 13.3 101.6 4.3 0.0 0.0 3.0 0.2 0.6 19.9 0.0 13.9 2.5 8.5 1.1 2.6 1.3 0.0 9.0 0.3 10.2 2.4 1.3 4.2 19.6 2.6 0.0 5.6 4.2 1.6 0.0 31.2 0.1 0.4 2.5 30.1 0.1 0.9 2.3 1.0 1.9 1.4 0.0 1.6 7.7 0.1 1.1 17.5 1.6 1.5 1.5 6.5 1.6 9.6 WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 32.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 25.6;Microglial cells: 19.7;Muller glia cells: 40.4;Urothelial cells: 16.2" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 231.4;BJ hTERT+: 143.5;BJ hTERT+ SV40 Large T+: 165.4;BJ hTERT+ SV40 Large T+ RasG12V: 136.4;fHDF/TERT166: 162.6;HBF TERT88: 144.1;hTEC/SVTERT24-B: 144.8;U-138 MG: 142.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061991 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" 3.0 2.3 3.6 4.1 4.1 0.5 3.0 2.8 3.7 5.5 1.8 24.6 4.3 7.2 5.0 14.9 6.2 2.8 4.0 2.8 5.3 1.9 4.6 3.0 2.6 4.7 3.9 8.2 1.5 9.0 11.2 3.9 4.6 32.4 5.8 5.4 15.7 20.0 1.4 5.3 5.0 5.4 3.9 5.2 6.4 1.8 4.2 3.7 2.0 6.7 3.0 13.9 9.7 3.1 0.3 0.1 1.4 0.2 34.6 61.2 0.0 231.4 143.5 165.4 136.4 8.7 0.9 2.9 0.4 162.6 111.1 3.5 3.3 0.0 144.1 55.0 7.9 12.8 0.0 0.0 8.5 0.2 0.1 51.3 3.3 144.8 41.3 66.6 0.0 0.1 9.5 51.9 39.4 0.1 0.0 0.3 5.7 0.2 0.5 0.0 2.3 4.0 2.0 0.0 1.0 3.2 4.9 0.5 0.2 17.7 0.2 0.9 0.0 142.4 5.9 56.7 119.7 13.9 2.2 0.7 13.9 0.0 1.5 0.0 1.8 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 3.6 4.1 2.8 3.7 2.8 5.3 4.7 3.9 4.6 3.9 4.2 3.1 0.9 0.0 0.6 7.5 1.5 0.9 11.0 1.9 25.6 1.8 0.7 6.5 2.2 0.0 3.3 0.0 0.0 1.0 0.2 2.4 0.0 1.1 0.2 1.7 10.4 1.4 0.0 0.0 6.9 0.7 1.1 8.0 0.5 2.7 0.0 0.3 0.4 1.7 5.3 0.0 7.9 1.9 2.0 2.1 2.9 0.5 2.1 2.7 3.6 19.7 4.1 40.4 0.0 4.0 5.6 2.8 5.0 2.6 4.5 8.8 1.0 0.2 4.3 2.7 6.6 7.9 4.3 0.7 5.7 7.7 1.3 0.7 0.2 0.0 1.7 16.2 WNT6 ENSG00000115596 "Wnt family member 6" Q9Y6F9 2 218859805-218874233 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 92.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.7" "Region enhanced" "Detected in many" "basal ganglia: 10.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "BEWO: 34.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.7" HPA070759 Approved "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" "HPA070759: AB_2732164" "unprognostic (1.86e-2)" "unprognostic (6.03e-2)" "unprognostic (5.14e-2)" "unprognostic (2.06e-1)" "unprognostic (5.32e-2)" "unprognostic (7.34e-2)" "unprognostic (8.08e-3)" "unprognostic (4.73e-2)" "unprognostic (1.27e-2)" "unprognostic (1.19e-1)" "unprognostic (1.21e-2)" "unprognostic (2.66e-1)" "unprognostic (1.24e-3)" "unprognostic (5.26e-2)" "unprognostic (4.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" 3.5 0.6 1.1 0.1 10.0 0.0 3.5 0.3 4.2 4.3 0.5 7.4 0.1 2.4 0.0 1.3 3.2 0.0 3.4 0.9 0.8 1.1 0.3 0.3 0.1 1.0 1.1 3.1 0.8 0.0 2.0 2.0 1.1 3.1 0.0 0.1 1.1 0.1 1.1 2.6 2.8 0.0 0.5 7.2 2.7 3.6 2.5 0.0 1.1 0.0 0.1 1.9 3.7 0.2 0.0 0.0 0.0 1.2 0.0 0.0 34.4 0.0 0.0 0.0 0.0 3.3 0.5 0.0 3.7 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 5.0 1.7 0.0 0.0 3.7 0.1 4.7 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 10.0 0.3 4.2 0.9 0.8 1.0 1.1 1.1 0.5 2.5 0.2 2.5 0.0 0.0 0.0 1.6 0.5 21.0 1.1 0.6 3.5 1.4 8.5 0.6 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.0 0.1 3.4 0.4 3.1 5.9 0.0 0.0 0.2 0.0 1.6 2.0 0.0 0.1 0.0 0.4 2.5 0.0 0.8 1.7 0.1 0.0 0.0 0.0 0.3 4.5 0.0 0.3 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.4 3.1 5.5 0.0 0.0 0.0 2.0 92.1 0.3 15.5 16.9 0.3 0.2 0.1 0.7 0.2 0.1 0.0 1.3 WNT7A Wnt-7a ENSG00000154764 "Wnt family member 7A" O00755 3 13816258-13880071 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;gallbladder: 2.3;placenta: 2.7" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 68.7;Extravillous trophoblasts: 147.5;Pancreatic endocrine cells: 98.8;Syncytiotrophoblasts: 185.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.2;ovarian cancer: 11.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 1.7;naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cell line enhanced" "Detected in some" "BEWO: 59.8;EFO-21: 56.0;PC-3: 19.9;RPTEC TERT1: 100.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015719, CAB025894" Approved "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB025894: , HPA015719: AB_1858856" "unprognostic (1.26e-2)" "unprognostic (4.60e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (3.02e-1)" "unprognostic (1.14e-3)" "unprognostic (2.49e-1)" "unprognostic (3.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (7.89e-2)" "unprognostic (3.78e-2)" "unprognostic (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (3.74e-1)" "unprognostic (8.88e-3)" 0.0 0.0 3.6 0.1 3.1 0.1 0.0 1.0 3.7 0.2 0.3 0.0 0.0 1.1 0.2 0.4 0.1 2.3 0.0 2.4 2.1 0.2 0.0 2.0 0.2 5.1 1.9 0.0 0.1 0.0 0.0 2.7 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.0 3.4 1.3 0.0 1.3 2.5 0.0 0.0 0.0 0.1 0.3 0.1 2.8 8.6 0.0 0.8 0.0 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 7.6 0.0 56.0 0.0 0.1 11.2 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 1.7 100.3 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.6 3.1 1.0 3.7 2.4 2.1 5.1 1.9 2.5 3.4 2.5 2.8 0.0 12.8 0.0 8.5 0.0 5.9 2.8 2.6 0.0 0.0 0.0 0.0 0.7 8.6 1.4 0.0 0.0 68.7 0.0 0.0 0.0 13.8 17.3 14.5 0.4 0.6 0.0 0.0 4.0 9.1 147.5 0.4 0.0 17.9 0.0 0.0 0.0 0.0 7.4 0.0 2.4 0.0 0.0 0.0 0.0 5.6 0.0 0.1 0.0 1.0 0.0 0.0 0.0 4.5 0.3 98.8 0.0 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.2 6.0 2.3 0.0 1.3 185.7 1.5 0.0 0.0 6.0 WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 17.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.6;Basal prostatic cells: 26.4;Basal squamous epithelial cells: 42.1;Club cells: 23.9;Pancreatic endocrine cells: 43.3;Prostatic glandular cells: 26.2;Urothelial cells: 46.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 119.4;HeLa: 103.7;RPTEC TERT1: 41.4;SK-BR-3: 51.0;U-87 MG: 93.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" 0.0 0.0 4.6 0.0 3.4 0.0 1.1 1.8 5.1 3.5 0.4 0.0 0.0 0.1 0.1 12.4 1.2 2.9 0.0 4.9 4.5 6.3 0.1 3.1 0.0 2.7 2.3 0.0 0.5 0.1 0.5 0.4 4.3 4.4 0.0 0.0 2.2 1.9 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.3 5.4 0.7 0.3 0.0 1.0 9.1 8.3 1.9 23.2 119.4 0.3 0.0 0.0 0.0 15.2 0.4 1.3 0.0 0.0 0.5 15.5 0.1 3.7 0.2 1.3 25.8 0.9 15.1 0.0 0.1 1.0 0.0 103.7 0.6 0.0 0.0 0.1 0.0 10.2 0.1 3.0 0.4 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.1 9.7 22.4 0.0 0.0 1.3 41.4 33.9 4.3 0.0 10.3 51.0 0.0 0.2 8.5 13.6 0.0 2.1 1.8 0.0 1.0 0.0 0.0 0.0 93.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 3.4 1.8 5.1 4.9 4.5 2.7 2.3 4.3 1.7 5.4 1.9 0.3 6.4 15.6 3.9 0.5 33.6 26.4 16.3 42.1 0.5 4.0 0.6 1.6 8.6 23.9 12.9 4.2 3.5 0.1 0.1 0.0 5.9 0.3 1.7 0.4 0.7 0.0 0.0 0.3 0.5 0.3 1.7 0.0 4.3 2.5 0.2 0.4 0.1 0.1 0.0 1.2 0.0 0.0 0.0 3.7 0.2 0.3 0.3 0.0 1.0 1.0 0.2 0.0 7.5 0.1 43.3 0.0 0.4 1.5 26.2 0.0 0.1 13.8 1.1 0.0 0.8 1.9 0.2 1.8 21.0 20.5 0.7 0.5 0.0 0.0 46.6 WNT8A WNT8D ENSG00000061492 "Wnt family member 8A" Q9H1J5 5 138083990-138092365 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.8;Inhibitory neurons: 1.5;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA038539 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038539: AB_10669646" "unprognostic (1.11e-5)" "unprognostic (4.11e-2)" "unprognostic (4.11e-2)" "unprognostic (5.32e-2)" 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WNT8B ENSG00000075290 "Wnt family member 8B" Q93098 10 100463009-100483744 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "parathyroid gland: 1.2" "Cell type enhanced" "Detected in single" "Oligodendrocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.3;JURKAT: 3.1;RPMI-8226: 1.0;SCLC-21H: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036570 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036570: AB_10670113" "unprognostic (6.92e-2)" "unprognostic (1.57e-1)" "unprognostic (7.13e-2)" "unprognostic (6.67e-2)" "unprognostic (3.88e-1)" "unprognostic (1.90e-1)" "unprognostic (2.64e-1)" "unprognostic (9.16e-4)" "unprognostic (1.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (7.83e-2)" "unprognostic (2.42e-3)" "unprognostic (5.02e-2)" "unprognostic (1.63e-1)" "unprognostic (2.68e-2)" "unprognostic (1.24e-2)" 0.0 0.8 0.1 0.0 0.4 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.4 1.2 0.1 0.0 0.0 0.2 0.0 0.9 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.1 0.2 0.0 1.0 0.0 0.7 1.1 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WNT9A WNT14 ENSG00000143816 "Wnt family member 9A" O14904 1 227918656-227947932 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.7;skeletal muscle: 26.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 5.1;Ionocytes: 6.1;Respiratory ciliated cells: 12.5;Urothelial cells: 5.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 16.2;PC-3: 10.8;RH-30: 16.4;SCLC-21H: 14.9;SiHa: 14.7;U-2197: 10.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.27e-2)" "unprognostic (3.24e-1)" "unprognostic (3.77e-3)" "unprognostic (4.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.39e-2)" "unprognostic (1.44e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.48e-1)" "unprognostic (1.38e-2)" "unprognostic (1.70e-2)" "unprognostic (3.72e-2)" "unprognostic (8.71e-2)" "unprognostic (5.04e-2)" "unprognostic (9.93e-2)" 3.3 1.4 0.4 1.1 0.6 0.1 3.0 0.6 0.8 4.1 7.7 18.7 1.3 5.3 0.4 5.8 5.5 2.1 10.1 0.7 0.9 0.9 0.2 3.9 0.3 1.2 0.9 9.8 2.8 1.2 2.8 2.1 2.1 2.5 1.1 0.0 2.4 1.0 26.3 1.1 6.0 4.3 0.5 1.0 5.9 1.5 0.7 1.1 2.0 2.8 0.3 4.9 3.4 0.5 1.0 3.3 0.4 0.1 0.4 0.7 8.1 1.1 0.9 0.1 0.0 0.0 8.8 0.0 4.7 1.5 3.3 16.2 0.4 0.8 0.0 1.6 0.6 0.0 6.0 0.2 0.4 0.0 0.5 0.1 4.0 0.1 0.1 0.3 1.0 0.0 0.0 0.1 1.8 2.2 0.0 0.0 1.0 0.0 10.8 0.2 16.4 1.7 4.6 1.1 14.9 0.0 14.7 6.6 0.0 5.2 8.4 1.8 0.6 2.1 1.3 10.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.6 0.8 0.7 0.9 1.2 0.9 2.1 0.5 0.7 0.5 0.3 3.2 0.6 0.3 0.0 0.9 1.3 3.6 0.0 0.0 3.1 1.3 1.4 0.0 4.3 1.8 0.0 0.3 0.2 0.8 0.0 0.7 0.1 2.1 2.1 0.4 3.0 0.0 0.7 1.3 0.2 5.1 1.5 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 2.9 6.1 0.0 0.4 0.1 4.4 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.9 1.1 0.0 4.5 0.1 1.8 0.1 0.1 12.5 0.0 0.0 1.3 1.1 0.0 1.8 3.9 0.3 0.0 0.2 0.1 0.1 5.3 WNT9B "WNT14B, WNT15" ENSG00000158955 "Wnt family member 9B" O14905 17 46833201-46886730 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 14.0;seminal vesicle: 9.7" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Microglial cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SuSa: 7.4" "Region enriched" "Detected in single" 7 "thalamus: 5.8" "Low region specificity" "Detected in all" "HPA058361, HPA059572" Approved "Secreted to extracellular matrix" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058361: AB_2683691, HPA059572: AB_2684067" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (3.18e-2)" "unprognostic (7.48e-3)" "unprognostic (3.37e-3)" "unprognostic (1.78e-1)" "unprognostic (8.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.66e-2)" "unprognostic (6.19e-4)" "unprognostic (1.13e-1)" "unprognostic (3.69e-2)" "unprognostic (7.52e-4)" "unprognostic (1.27e-1)" "unprognostic (2.70e-1)" "unprognostic (1.37e-1)" 0.3 0.3 0.6 0.0 1.0 0.1 0.3 0.3 0.8 0.1 0.0 0.0 1.7 0.2 1.2 0.1 0.1 0.1 0.5 0.4 0.6 3.2 0.7 0.2 0.1 0.7 1.3 0.0 0.1 14.0 0.0 0.6 0.3 0.1 0.0 0.1 0.0 9.7 0.1 2.4 0.9 0.2 0.5 1.0 0.0 0.1 2.3 0.0 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 1.0 0.3 0.8 0.4 0.6 0.7 1.3 0.3 0.5 2.3 0.5 0.1 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 XCL1 "ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1" ENSG00000143184 "X-C motif chemokine ligand 1" P47992 1 168576605-168582069 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6" "Group enriched" "Detected in many" 4 "dendritic cells: 185.3;T-cells: 213.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "NK-cell: 88.5" "Lineage enriched" "Detected in many" 14 "NK-cells: 88.5" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 4.1;SCLC-21H: 3.3;SuSa: 6.1;U-266/70: 5.0;U-266/84: 1.9" "Not detected" "Not detected" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (5.38e-3)" "unprognostic (5.72e-2)" "unprognostic (8.23e-3)" "unprognostic (4.19e-3)" "unprognostic (1.43e-1)" "unprognostic (6.10e-2)" "unprognostic (2.96e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (4.61e-1)" "unprognostic (8.85e-2)" "unprognostic (5.34e-10)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (5.47e-2)" "unprognostic (2.15e-2)" 0.5 0.1 0.1 1.0 0.1 3.5 1.0 0.0 0.2 1.0 0.0 0.7 1.0 2.2 0.8 0.2 0.6 1.1 0.5 0.1 0.2 0.5 2.6 1.8 2.3 0.1 0.1 0.2 0.5 0.0 0.1 2.2 0.2 0.4 1.0 0.0 1.5 0.3 0.1 0.1 1.5 0.3 0.1 4.6 1.2 0.2 0.6 4.1 0.3 0.0 1.6 0.9 0.4 0.1 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.3 0.0 0.3 0.0 0.0 6.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 5.0 1.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 6.2 0.0 0.2 0.0 1.0 5.9 0.0 0.0 0.3 4.0 0.3 88.5 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.6 0.1 2.3 3.2 5.5 0.0 1.5 4.0 0.5 0.0 2.2 0.0 1.3 1.5 2.0 1.5 0.0 0.0 0.0 1.4 185.3 0.7 0.0 0.0 1.3 2.0 1.9 1.9 0.0 8.4 0.0 0.2 1.2 1.9 8.2 2.9 2.5 0.0 1.4 0.9 0.4 0.0 0.1 0.8 0.0 1.9 10.6 0.0 0.0 3.1 39.2 0.0 0.1 0.0 42.2 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 0.3 1.7 0.2 0.2 1.8 4.3 0.8 213.4 0.0 0.4 0.1 XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.4" "Group enriched" "Detected in many" 10 "dendritic cells: 513.6;NK-cells: 277.1;T-cells: 240.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 423.5" "Lineage enriched" "Detected in many" 8 "NK-cells: 423.5" "Cell line enhanced" "Detected in some" "CACO-2: 3.0;RT4: 1.1;SuSa: 1.1" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" 1.1 0.8 0.3 3.2 0.3 14.1 0.9 0.3 0.5 1.0 0.4 1.9 3.2 3.6 0.9 0.6 1.8 1.9 0.7 0.3 0.4 0.4 5.6 3.3 5.6 0.5 0.3 0.4 0.6 0.3 0.2 1.4 0.4 0.5 1.5 0.0 1.9 1.0 0.3 0.1 2.0 1.4 0.4 13.4 2.9 0.3 0.6 3.8 0.6 0.5 3.6 2.0 0.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.4 47.2 0.2 2.7 0.3 3.6 50.1 0.3 0.1 2.1 37.1 1.9 423.5 0.3 0.1 0.0 17.1 0.3 0.3 0.3 0.5 0.3 0.4 0.5 0.3 0.4 0.4 0.6 0.4 2.9 0.0 1.1 0.0 3.3 2.4 0.0 0.0 1.8 0.0 1.6 1.4 0.8 0.0 0.0 0.0 0.0 0.1 513.6 0.3 0.0 0.1 0.0 2.4 2.0 1.0 0.0 19.2 0.0 0.0 0.0 1.1 8.2 2.2 1.3 0.0 1.4 0.6 0.4 0.0 0.0 0.7 0.0 5.0 4.0 0.0 0.0 3.7 33.8 0.0 0.8 0.0 277.1 0.0 0.0 0.0 1.1 0.0 13.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.9 1.1 0.0 240.6 0.0 0.1 0.1 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "ASC diff: 55.1;ASC TERT1: 34.0;U-2197: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA 150000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 6.4 6.2 6.2 4.9 8.0 7.2 4.5 2.3 6.3 7.8 8.5 8.8 4.3 7.9 1.0 5.1 3.7 2.3 4.2 8.8 3.6 1.0 0.3 3.5 5.1 3.7 4.3 5.3 2.8 0.9 0.6 6.0 4.2 2.7 5.2 8.3 2.5 4.5 1.1 5.0 5.3 5.7 1.6 5.4 3.4 2.3 3.6 4.1 2.2 1.2 4.3 4.3 4.6 4.6 0.0 0.3 8.0 0.1 55.1 34.0 9.6 25.6 12.9 2.7 1.0 0.3 0.6 6.1 0.0 31.3 0.9 0.6 0.0 5.1 4.5 12.1 0.6 8.0 0.0 0.0 0.6 11.5 10.2 12.6 0.7 15.0 2.4 4.6 0.0 0.3 0.0 23.8 2.8 0.8 0.1 12.4 8.5 4.4 0.0 3.5 0.0 1.2 0.0 11.5 2.0 15.2 1.9 7.9 1.4 5.9 1.9 7.2 0.0 24.6 2.9 57.2 0.0 26.4 1.4 11.6 28.9 12.8 22.4 0.3 0.2 0.4 0.2 1.2 0.3 0.1 0.1 0.1 0.4 0.3 0.2 0.1 0.1 0.4 2.0 0.1 0.3 0.2 6.2 8.0 2.3 6.3 8.8 3.6 3.7 4.3 4.2 1.6 3.6 4.6 1.0 3.2 2.5 45.4 9.2 7.9 1.6 0.0 1.2 12.9 3.8 3.7 3.4 0.0 0.7 0.0 98.0 12.7 12.4 9.1 0.0 1.5 0.5 0.5 24.7 2.9 12.6 7.4 172.8 1.6 20.1 12.2 2.6 0.8 2.5 6.4 1.4 0.2 3.5 0.0 72.8 4.3 4.1 9.7 27.6 0.8 12.8 8.5 3.6 29.0 6.1 1.9 11.3 1194.8 63.0 4.0 7.4 50.0 6.2 5.3 6.1 0.2 0.0 4.4 6.6 7.9 5.9 0.3 1.6 4.1 18.5 13.1 7.7 8.1 6.9 6.4 XYLT2 "PXYLT2, XT-II" ENSG00000015532 "Xylosyltransferase 2" Q9H1B5 17 50346126-50363138 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "stomach 1: 86.7" "Group enriched" "Detected in many" 6 "Early spermatids: 316.4;Late spermatids: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1100000 "Cluster 39: Non-specific - mRNA processing" "Cluster 4: Stomach - Digestion" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (1.52e-1)" "unprognostic (2.84e-1)" "unprognostic (1.65e-1)" "unprognostic (8.07e-2)" "unprognostic (1.90e-3)" "unprognostic (1.90e-1)" "unprognostic (7.29e-3)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.54e-2)" "unprognostic (2.81e-1)" "unprognostic (7.63e-2)" "unprognostic (5.15e-2)" "unprognostic (7.38e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-2)" 7.4 9.7 4.9 6.6 5.2 4.5 8.1 8.0 8.2 12.3 8.7 10.0 9.6 11.4 5.3 8.4 11.8 6.6 9.1 5.6 3.0 8.9 7.5 7.3 9.3 4.1 5.6 13.6 12.9 9.4 6.4 8.6 3.8 13.6 3.6 4.5 12.2 10.1 5.8 15.3 8.7 5.2 2.5 10.1 86.7 6.7 7.0 8.6 9.3 2.4 4.0 12.0 10.9 5.3 21.1 26.2 7.0 5.9 9.7 9.4 18.4 19.3 17.4 17.2 19.1 28.3 15.5 10.9 47.6 17.3 14.9 15.8 2.4 27.0 3.7 54.3 18.5 24.6 8.6 12.4 13.3 7.8 12.5 12.8 16.4 13.6 6.3 16.9 14.9 9.4 4.4 8.8 11.3 27.5 14.4 10.7 6.5 14.0 18.0 7.2 20.4 9.0 9.5 10.8 3.6 9.0 12.9 11.9 20.3 8.0 57.4 7.5 17.4 38.4 19.2 20.9 17.3 48.0 23.6 3.9 40.4 12.3 10.6 3.7 2.0 1.5 2.7 1.2 2.7 1.3 2.7 3.6 2.4 2.2 2.7 2.5 1.9 3.6 1.1 1.6 2.5 2.9 4.9 5.2 8.0 8.2 5.6 3.0 4.1 5.6 3.8 2.5 7.0 5.3 7.5 9.6 6.1 13.1 3.9 5.7 3.2 7.3 5.7 8.3 3.9 5.7 8.4 10.0 4.4 1.8 29.2 7.0 3.8 7.5 0.0 7.1 316.4 4.6 6.7 6.8 10.8 0.8 4.9 6.2 5.4 9.1 17.3 6.8 1.3 9.6 10.4 8.0 3.6 6.7 7.2 9.4 2.0 6.0 1.4 91.4 12.5 3.8 7.2 6.5 2.7 5.9 5.2 6.6 4.7 6.8 3.5 17.3 4.7 2.0 4.6 2.8 3.2 6.1 26.3 6.9 6.7 2.4 4.3 3.4 3.1 1.5 4.8 5.3 11.1 1.4 ZBED3 MGC15435 ENSG00000132846 "Zinc finger BED-type containing 3" Q96IU2 5 77072072-77087285 "Predicted intracellular proteins, Predicted secreted proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.7;JURKAT: 31.0;MOLT-4: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055995 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA055995: AB_2683000" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.45e-2)" "unprognostic (6.96e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "unprognostic (3.63e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.08e-1)" "unprognostic (1.92e-1)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" 10.3 3.3 9.3 1.9 14.2 2.6 8.8 9.4 10.8 6.7 7.5 4.2 3.9 10.2 7.4 2.4 7.0 3.5 4.6 7.8 9.2 10.0 10.7 5.0 1.9 16.0 12.2 7.9 7.6 8.4 3.9 2.4 10.9 5.1 4.3 3.8 6.0 6.6 2.7 2.6 3.3 8.7 9.9 3.6 6.4 1.9 13.5 4.8 11.2 3.8 1.9 3.0 3.7 17.1 5.2 4.2 5.4 29.7 22.1 1.5 0.3 1.7 5.0 2.6 6.9 9.1 2.4 0.0 10.9 3.4 1.1 0.6 2.9 1.8 2.3 1.7 5.8 4.0 9.1 10.4 13.1 5.5 1.5 24.6 6.8 1.3 5.1 4.2 8.3 31.0 0.0 11.0 1.6 5.2 29.4 0.8 3.5 1.4 2.5 12.1 10.3 1.7 12.3 2.0 5.9 12.4 6.1 5.0 8.7 2.1 7.5 3.8 3.3 2.3 4.5 5.1 7.0 8.0 8.2 11.5 3.6 10.4 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 9.3 14.2 9.4 10.8 7.8 9.2 16.0 12.2 10.9 9.9 13.5 17.1 10.5 0.0 2.8 8.1 1.7 1.3 3.8 0.3 4.0 8.4 13.5 13.6 10.7 12.8 2.0 12.9 12.5 1.5 2.0 3.1 17.6 4.1 3.3 16.5 13.5 11.7 16.2 5.0 3.3 6.0 0.3 9.3 11.7 12.5 1.3 20.2 12.1 31.8 9.6 3.3 8.5 5.3 0.0 13.6 4.9 2.2 17.7 9.0 7.2 5.6 5.1 13.8 3.1 16.1 18.3 2.7 3.4 11.3 1.4 5.6 1.9 17.2 0.1 17.0 0.0 21.4 7.7 1.5 3.4 2.2 1.4 0.3 1.2 25.6 7.1 1.8 ZG16 "hZG16, JCLN, JCLN1, ZG16A" ENSG00000174992 "Zymogen granule protein 16" O60844 16 29778256-29782973 "Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "intestine: 479.5" "Cell type enriched" "Detected in some" 10 "Intestinal goblet cells: 20216.0" "Cancer enriched" "Detected in some" 6 "colorectal cancer: 21.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-BR-3: 2.3" "Not detected" "Not detected" "HPA052066, HPA052512" Enhanced "Secreted to digestive system" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA052066: AB_2681716, HPA052512: AB_2681857" "unprognostic (1.64e-2)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (8.20e-2)" "unprognostic (3.50e-2)" "unprognostic (1.93e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-1)" "unprognostic (7.77e-2)" "unprognostic (3.27e-1)" "unprognostic (2.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" 0.5 0.0 0.0 7.8 0.2 0.1 0.7 0.1 0.1 0.0 0.0 362.9 57.8 0.6 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.4 22.2 0.0 0.2 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 479.5 0.1 0.0 0.5 0.0 0.1 136.9 12.9 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.6 0.0 1107.2 0.0 0.0 0.0 0.1 0.0 0.1 145.5 0.0 0.1 11.9 0.0 0.1 0.0 0.2 40.1 0.0 0.4 44.6 0.0 0.0 0.1 20216.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 484.8 0.0 0.0 0.2 1950.6 1.6 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 7.1 0.0 306.7 0.3 ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830169-2839585 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 717 "salivary gland: 63926.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 194.0;Basal respiratory cells: 181.6;Breast glandular cells: 154.9;Club cells: 343.9;Intestinal goblet cells: 232.2;Prostatic glandular cells: 398.1;Urothelial cells: 357.4" "Cancer enhanced" "Detected in many" "prostate cancer: 47.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.3;intermediate monocyte: 11.4;non-classical monocyte: 7.4" "Lineage enriched" "Detected in many" 7 "monocytes: 11.4" "Cell line enhanced" "Detected in some" "MCF7: 27.1;OE19: 57.5;SK-BR-3: 24.1;T-47d: 22.2" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 690000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA041125: AB_10794264, HPA053549: AB_2682184" "unprognostic (5.29e-2)" "unprognostic (2.71e-1)" "unprognostic (4.37e-2)" "prognostic favorable (3.48e-6)" "unprognostic (1.39e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (4.13e-2)" "unprognostic (1.01e-1)" "unprognostic (3.45e-3)" "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (8.33e-2)" 2.5 13.2 0.0 3.9 0.0 4.6 33.1 0.0 0.1 33.0 0.0 13.6 11.5 0.6 1.5 25.3 4.4 34.4 9.0 0.0 0.0 2.6 8.2 3.3 0.3 0.0 0.8 10.3 46.6 30.4 6.0 4.8 0.1 89.1 17.8 0.0 63926.2 7.1 6.1 47.7 9.6 0.4 0.0 4.2 33.2 4.4 0.0 0.2 2.9 0.1 5.9 11.2 16.3 0.0 0.0 1.1 0.0 0.0 0.3 1.9 0.2 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.3 0.0 0.2 2.1 0.0 4.4 0.0 0.0 0.0 9.0 2.8 2.4 1.6 0.0 0.0 0.1 0.2 0.0 1.2 0.1 0.0 0.0 0.2 3.6 0.2 27.1 0.0 0.4 0.1 57.5 5.0 0.0 0.0 8.6 0.2 6.3 0.0 0.0 0.1 24.1 0.0 0.1 22.2 0.0 3.1 0.1 0.5 1.9 0.1 0.0 0.5 0.3 0.3 6.5 0.3 1.7 6.3 0.0 0.0 11.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.4 1.2 7.4 0.0 0.5 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 9.1 194.0 181.6 0.0 0.0 154.9 82.5 0.0 70.1 343.9 1.8 0.0 0.1 2.0 107.1 0.0 5.9 7.7 3.5 1.6 2.8 58.2 0.4 0.0 28.1 3.2 1.8 21.9 13.0 5.7 1.7 0.7 0.1 14.6 0.0 0.0 232.2 140.4 4.6 0.5 5.7 0.0 4.4 83.6 0.0 5.6 0.0 0.0 0.0 0.0 46.4 65.3 0.0 0.0 398.1 12.5 0.0 74.7 0.0 0.0 0.0 19.2 1.4 0.6 9.5 24.0 0.3 2.5 21.3 76.7 357.4 ZP1 ENSG00000149506 "Zona pellucida glycoprotein 1" P60852 11 60867562-60875693 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Early spermatids: 32.3;Late spermatids: 87.6" "Cancer enhanced" "Detected in single" "prostate cancer: 0.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 32 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 32 "dendritic cells: 3.1" "Group enriched" "Detected in some" 40 "RPMI-8226: 12.4;SK-BR-3: 3.3" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (6.40e-3)" "unprognostic (2.18e-4)" "unprognostic (1.63e-1)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (7.02e-2)" "unprognostic (8.27e-2)" "unprognostic (9.95e-2)" "unprognostic (1.94e-2)" "unprognostic (8.15e-3)" "unprognostic (2.52e-1)" "unprognostic (9.25e-4)" "unprognostic (5.31e-13)" "unprognostic (4.13e-2)" "unprognostic (2.38e-1)" "unprognostic (6.27e-2)" "unprognostic (5.61e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 1.3 0.3 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.1 0.7 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 32.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 87.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.1 5.0 1.9 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.1 ZP2 ZPA ENSG00000103310 "Zona pellucida glycoprotein 2" Q05996 16 21197450-21214510 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 4.8" "Cell type enriched" "Detected in single" 15 "Proximal enterocytes: 7.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "cerebellum: 4.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 37 "HDLM-2: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA011296 Enhanced "Secreted in female reproductive system" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA011296: AB_1859485" "unprognostic (2.35e-2)" "unprognostic (3.12e-2)" "unprognostic (6.60e-2)" "unprognostic (9.83e-2)" "unprognostic (3.44e-3)" "unprognostic (3.12e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.1 4.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 ZP3 "ZP3-372, ZP3-424, ZP3A, ZP3B, ZPC" ENSG00000188372 "Zona pellucida glycoprotein 3" P21754 7 76397518-76442071 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 78.4;Early spermatids: 45.6;Late spermatids: 89.7;Spermatocytes: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 35.2;hTCEpi: 37.8;Karpas-707: 52.0;MCF7: 71.6;OE19: 30.2" "Not detected" "Not detected" "HPA054061, HPA071198" Supported "Secreted in female reproductive system" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA054061: AB_2682363, HPA071198: " "unprognostic (6.48e-2)" "unprognostic (3.08e-1)" "unprognostic (7.74e-2)" "unprognostic (1.59e-1)" "unprognostic (9.04e-2)" "unprognostic (2.68e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (3.10e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (1.02e-6)" "unprognostic (1.33e-1)" "unprognostic (1.42e-2)" "unprognostic (6.72e-2)" "unprognostic (2.13e-1)" 1.0 2.9 1.1 0.7 1.9 2.2 3.1 1.3 1.7 1.1 1.9 2.4 1.9 0.8 2.2 4.2 4.0 0.6 0.3 1.0 1.1 1.0 0.8 0.5 0.8 1.2 1.0 2.8 4.1 0.6 1.2 0.6 1.3 1.4 2.6 0.5 1.5 0.7 1.4 4.1 1.1 1.1 1.0 1.8 1.1 1.3 1.2 0.5 0.8 0.4 0.9 0.7 2.4 1.3 17.6 35.2 0.2 18.4 0.9 1.0 0.9 1.2 2.8 0.3 3.3 1.3 15.2 0.1 0.6 4.6 0.5 4.3 3.8 1.2 0.3 9.5 8.5 2.8 10.5 0.1 8.0 0.7 5.2 1.5 37.8 3.9 1.1 0.1 0.7 9.1 4.0 52.0 0.0 71.6 1.6 9.1 3.8 30.2 10.0 0.1 1.5 3.9 1.6 0.2 7.6 0.0 4.6 23.9 0.6 0.4 15.6 3.0 2.2 0.1 1.8 0.1 0.1 15.4 13.4 0.1 1.5 20.2 3.2 0.6 9.4 0.1 0.1 4.0 0.4 2.4 1.1 0.5 9.6 1.1 4.5 3.2 0.8 0.2 4.5 2.0 0.1 3.1 1.1 1.9 1.3 1.7 1.0 1.1 1.2 1.0 1.3 1.0 1.2 1.3 2.6 3.2 3.6 1.3 2.9 8.5 5.8 78.4 9.6 1.5 9.3 12.6 0.8 4.3 21.1 1.8 0.0 5.8 2.7 5.3 0.0 2.9 45.6 1.6 1.4 2.8 4.2 3.0 3.3 4.3 3.6 1.9 1.1 3.0 0.0 5.0 2.9 0.8 7.0 1.7 2.7 4.7 6.1 7.2 4.6 89.7 4.4 5.7 3.6 2.8 5.4 4.4 0.0 1.5 1.7 3.3 8.6 5.7 4.2 5.5 0.6 3.7 20.4 2.0 6.6 3.1 2.5 34.9 12.4 9.0 9.9 9.3 2.2 2.7 7.6 17.1 ZP4 ZPB ENSG00000116996 "Zona pellucida glycoprotein 4" Q12836 1 237877864-237890922 "Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "BJ hTERT+: 3.2" "Not detected" "Not detected" HPA008547 Supported "Secreted in female reproductive system" NA NA "Cluster 10: BJ & FHDF - ECM organization" "HPA008547: AB_1080766" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (4.59e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZPBP "SP38, ZPBP1" ENSG00000042813 "Zona pellucida binding protein" Q9BS86 7 49850421-50121329 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 143.1" "Group enriched" "Detected in some" 7 "Early spermatids: 973.0;Spermatocytes: 691.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058673 Enhanced "Secreted in male reproductive system" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA058673: AB_2683794" "unprognostic (1.16e-1)" "unprognostic (6.46e-2)" "unprognostic (7.80e-2)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.15e-7)" "unprognostic (9.49e-2)" "unprognostic (2.34e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 143.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 15.0 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 973.0 0.1 0.1 0.4 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 22.9 0.0 0.0 0.0 0.0 116.0 11.1 0.4 0.0 1.9 0.0 1.9 0.0 9.0 0.5 0.1 0.0 7.9 0.0 0.2 0.0 0.5 0.6 20.2 6.6 0.0 0.0 691.6 17.1 0.0 0.3 0.0 0.0 0.2 0.0 0.2 ZPBP2 "MGC41930, ZPBPL" ENSG00000186075 "Zona pellucida binding protein 2" Q6X784 17 39868202-39877896 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 100 "testis: 95.3" "Group enriched" "Detected in some" 5 "Early spermatids: 273.9;Spermatocytes: 598.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.3;U-698: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027997, HPA053070" Enhanced "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA027997: AB_1859488, HPA053070: AB_2682033" "unprognostic (2.14e-2)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (2.87e-1)" "unprognostic (5.39e-1)" "unprognostic (2.54e-3)" 0.1 0.1 0.4 0.3 0.2 0.3 0.2 0.7 0.6 0.0 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.2 0.1 0.7 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.6 0.1 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.2 95.3 0.3 0.1 0.1 0.1 0.9 0.1 0.0 0.6 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.0 1.3 0.1 0.2 0.1 0.0 0.2 0.1 0.2 0.3 0.6 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.4 0.3 0.3 0.2 0.4 1.0 0.1 0.1 0.4 0.1 0.0 0.2 0.1 0.5 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.4 0.1 4.9 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.7 0.6 0.3 0.5 0.2 0.1 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 273.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.2 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 598.2 19.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1