[{"Gene":"ACTB","Gene synonym":[],"Ensembl":"ENSG00000075624","Gene description":"Actin beta","Uniprot":["P60709"],"Chromosome":"7","Position":"5526409-5563902","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Dystonia","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"22882.9","Pancreatic endocrine cells":"14370.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002621","HPA041264","HPA041271"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5800000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002621":null,"HPA041264":"AB_2677383","HPA041271":"AB_2677386"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.51e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.78e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Tissue RNA - adipose tissue [nTPM]":"2558.1","Tissue RNA - adrenal gland [nTPM]":"1235.8","Tissue RNA - amygdala [nTPM]":"2143.2","Tissue RNA - appendix [nTPM]":"4250.8","Tissue RNA - basal ganglia [nTPM]":"2321.0","Tissue RNA - bone marrow [nTPM]":"3598.4","Tissue RNA - breast [nTPM]":"2009.8","Tissue RNA - cerebellum [nTPM]":"2400.1","Tissue RNA - cerebral cortex [nTPM]":"2776.1","Tissue RNA - cervix [nTPM]":"2274.6","Tissue RNA - choroid plexus [nTPM]":"2183.3","Tissue RNA - colon [nTPM]":"6581.2","Tissue RNA - duodenum [nTPM]":"1659.0","Tissue RNA - endometrium 1 [nTPM]":"5033.9","Tissue RNA - epididymis [nTPM]":"1630.3","Tissue RNA - esophagus [nTPM]":"2928.9","Tissue RNA - fallopian tube [nTPM]":"2943.6","Tissue RNA - gallbladder [nTPM]":"1772.1","Tissue RNA - heart muscle [nTPM]":"817.6","Tissue RNA - hippocampal formation [nTPM]":"2355.6","Tissue RNA - hypothalamus [nTPM]":"2315.8","Tissue RNA - kidney [nTPM]":"1313.6","Tissue RNA - liver [nTPM]":"1759.9","Tissue RNA - lung [nTPM]":"2876.0","Tissue RNA - lymph node [nTPM]":"4394.2","Tissue RNA - medulla oblongata [nTPM]":"2654.8","Tissue RNA - midbrain [nTPM]":"2338.9","Tissue RNA - ovary [nTPM]":"1711.5","Tissue RNA - pancreas [nTPM]":"761.9","Tissue RNA - parathyroid gland [nTPM]":"838.5","Tissue RNA - pituitary gland [nTPM]":"731.4","Tissue RNA - placenta [nTPM]":"1817.2","Tissue RNA - pons [nTPM]":"2569.2","Tissue RNA - prostate [nTPM]":"2027.1","Tissue RNA - rectum [nTPM]":"2338.4","Tissue RNA - retina [nTPM]":"488.2","Tissue RNA - salivary gland [nTPM]":"1470.2","Tissue RNA - seminal vesicle [nTPM]":"2943.2","Tissue RNA - skeletal muscle [nTPM]":"465.1","Tissue RNA - skin 1 [nTPM]":"1541.7","Tissue RNA - small intestine [nTPM]":"2825.9","Tissue RNA - smooth muscle [nTPM]":"5736.8","Tissue RNA - spinal cord [nTPM]":"2457.9","Tissue RNA - spleen [nTPM]":"3009.5","Tissue RNA - stomach 1 [nTPM]":"2869.7","Tissue RNA - testis [nTPM]":"558.3","Tissue RNA - thalamus [nTPM]":"2483.4","Tissue RNA - thymus [nTPM]":"3278.4","Tissue RNA - thyroid gland [nTPM]":"1317.9","Tissue RNA - tongue [nTPM]":"524.0","Tissue RNA - tonsil [nTPM]":"4602.3","Tissue RNA - urinary bladder [nTPM]":"3720.8","Tissue RNA - vagina [nTPM]":"2223.5","Tissue RNA - white matter [nTPM]":"3045.4","Cell RNA - A-431 [nTPM]":"7791.1","Cell RNA - A549 [nTPM]":"5198.8","Cell RNA - AF22 [nTPM]":"5604.1","Cell RNA - AN3-CA [nTPM]":"4658.2","Cell RNA - ASC diff [nTPM]":"2321.1","Cell RNA - ASC TERT1 [nTPM]":"3120.3","Cell RNA - BEWO [nTPM]":"6654.3","Cell RNA - BJ [nTPM]":"6049.6","Cell RNA - BJ hTERT+ [nTPM]":"4853.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6209.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4619.4","Cell RNA - CACO-2 [nTPM]":"8249.5","Cell RNA - CAPAN-2 [nTPM]":"4361.9","Cell RNA - Daudi [nTPM]":"4522.7","Cell RNA - EFO-21 [nTPM]":"4557.0","Cell RNA - fHDF\/TERT166 [nTPM]":"9445.4","Cell RNA - GAMG [nTPM]":"4904.8","Cell RNA - HaCaT [nTPM]":"4820.3","Cell RNA - HAP1 [nTPM]":"3279.5","Cell RNA - HBEC3-KT [nTPM]":"9453.9","Cell RNA - HBF TERT88 [nTPM]":"4507.4","Cell RNA - HDLM-2 [nTPM]":"5324.6","Cell RNA - HEK 293 [nTPM]":"1668.7","Cell RNA - HEL [nTPM]":"3974.3","Cell RNA - HeLa [nTPM]":"4579.6","Cell RNA - Hep G2 [nTPM]":"4520.6","Cell RNA - HHSteC [nTPM]":"3538.8","Cell RNA - HL-60 [nTPM]":"4733.2","Cell RNA - HMC-1 [nTPM]":"9853.8","Cell RNA - HSkMC [nTPM]":"4098.5","Cell RNA - hTCEpi [nTPM]":"2786.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6863.0","Cell RNA - hTERT-HME1 [nTPM]":"1738.0","Cell RNA - hTERT-RPE1 [nTPM]":"4128.6","Cell RNA - HUVEC TERT2 [nTPM]":"5073.2","Cell RNA - JURKAT [nTPM]":"3561.3","Cell RNA - K-562 [nTPM]":"2189.7","Cell RNA - Karpas-707 [nTPM]":"3513.0","Cell RNA - LHCN-M2 [nTPM]":"6603.4","Cell RNA - MCF7 [nTPM]":"7531.9","Cell RNA - MOLT-4 [nTPM]":"4055.1","Cell RNA - NB-4 [nTPM]":"13162.1","Cell RNA - NTERA-2 [nTPM]":"6813.7","Cell RNA - OE19 [nTPM]":"2468.5","Cell RNA - PC-3 [nTPM]":"3490.8","Cell RNA - REH [nTPM]":"5658.6","Cell RNA - RH-30 [nTPM]":"3351.4","Cell RNA - RPMI-8226 [nTPM]":"3419.7","Cell RNA - RPTEC TERT1 [nTPM]":"5904.6","Cell RNA - RT4 [nTPM]":"3175.8","Cell RNA - SCLC-21H [nTPM]":"1633.1","Cell RNA - SH-SY5Y [nTPM]":"2746.9","Cell RNA - SiHa [nTPM]":"5754.7","Cell RNA - SK-BR-3 [nTPM]":"5822.1","Cell RNA - SK-MEL-30 [nTPM]":"2400.3","Cell RNA - SuSa [nTPM]":"5088.3","Cell RNA - T-47d [nTPM]":"5859.7","Cell RNA - THP-1 [nTPM]":"5314.8","Cell RNA - TIME [nTPM]":"7975.3","Cell RNA - U-138 MG [nTPM]":"10437.4","Cell RNA - U-2 OS [nTPM]":"7019.9","Cell RNA - U-2197 [nTPM]":"7000.1","Cell RNA - U-251 MG [nTPM]":"8802.8","Cell RNA - U-266\/70 [nTPM]":"1902.3","Cell RNA - U-266\/84 [nTPM]":"2442.5","Cell RNA - U-698 [nTPM]":"5082.1","Cell RNA - U-87 MG [nTPM]":"5772.0","Cell RNA - U-937 [nTPM]":"6622.6","Cell RNA - WM-115 [nTPM]":"12412.7","Blood RNA - basophil [nTPM]":"14674.1","Blood RNA - classical monocyte [nTPM]":"18104.2","Blood RNA - eosinophil [nTPM]":"29636.6","Blood RNA - gdT-cell [nTPM]":"10647.1","Blood RNA - intermediate monocyte [nTPM]":"19648.6","Blood RNA - MAIT T-cell [nTPM]":"8327.7","Blood RNA - memory B-cell [nTPM]":"5139.6","Blood RNA - memory CD4 T-cell [nTPM]":"7639.4","Blood RNA - memory CD8 T-cell [nTPM]":"9512.9","Blood RNA - myeloid DC [nTPM]":"19292.5","Blood RNA - naive B-cell [nTPM]":"4844.1","Blood RNA - naive CD4 T-cell [nTPM]":"5592.0","Blood RNA - naive CD8 T-cell [nTPM]":"7894.3","Blood RNA - neutrophil [nTPM]":"18040.6","Blood RNA - NK-cell [nTPM]":"6233.1","Blood RNA - non-classical monocyte [nTPM]":"22870.8","Blood RNA - plasmacytoid DC [nTPM]":"7122.2","Blood RNA - T-reg [nTPM]":"11463.2","Blood RNA - total PBMC [nTPM]":"37406.8","Brain RNA - amygdala [nTPM]":"2143.2","Brain RNA - basal ganglia [nTPM]":"2321.0","Brain RNA - cerebellum [nTPM]":"2400.1","Brain RNA - cerebral cortex [nTPM]":"2776.1","Brain RNA - hippocampal formation [nTPM]":"2355.6","Brain RNA - hypothalamus [nTPM]":"2315.8","Brain RNA - medulla oblongata [nTPM]":"2654.8","Brain RNA - midbrain [nTPM]":"2338.9","Brain RNA - pons [nTPM]":"2569.2","Brain RNA - spinal cord [nTPM]":"2457.9","Brain RNA - thalamus [nTPM]":"2483.4","Brain RNA - white matter [nTPM]":"3045.4","Single Cell Type RNA - Adipocytes [nTPM]":"2775.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1150.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"680.4","Single Cell Type RNA - Astrocytes [nTPM]":"142.4","Single Cell Type RNA - B-cells [nTPM]":"4118.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5737.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9776.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5792.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3110.2","Single Cell Type RNA - Bipolar cells [nTPM]":"146.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1564.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2047.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"145.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1080.9","Single Cell Type RNA - Club cells [nTPM]":"2763.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"2144.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"85.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3647.7","Single Cell Type RNA - dendritic cells [nTPM]":"3989.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"3419.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"2277.4","Single Cell Type RNA - Ductal cells [nTPM]":"6508.8","Single Cell Type RNA - Early spermatids [nTPM]":"101.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1422.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2344.0","Single Cell Type RNA - Endothelial cells [nTPM]":"2768.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1451.5","Single Cell Type RNA - Erythroid cells [nTPM]":"3170.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"129.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6365.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12480.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2958.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3136.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2041.6","Single Cell Type RNA - granulocytes [nTPM]":"1539.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2372.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2163.5","Single Cell Type RNA - Hepatocytes [nTPM]":"2590.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"13977.7","Single Cell Type RNA - Horizontal cells [nTPM]":"269.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"101.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2006.7","Single Cell Type RNA - Ionocytes [nTPM]":"3694.5","Single Cell Type RNA - Kupffer cells [nTPM]":"7392.0","Single Cell Type RNA - Langerhans cells [nTPM]":"11420.0","Single Cell Type RNA - Late spermatids [nTPM]":"199.7","Single Cell Type RNA - Leydig cells [nTPM]":"1766.7","Single Cell Type RNA - Macrophages [nTPM]":"8486.4","Single Cell Type RNA - Melanocytes [nTPM]":"2995.4","Single Cell Type RNA - Microglial cells [nTPM]":"259.5","Single Cell Type RNA - monocytes [nTPM]":"22882.9","Single Cell Type RNA - Muller glia cells [nTPM]":"1654.4","Single Cell Type RNA - NK-cells [nTPM]":"5237.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"116.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"302.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14370.0","Single Cell Type RNA - Paneth cells [nTPM]":"2899.8","Single Cell Type RNA - Peritubular cells [nTPM]":"2680.3","Single Cell Type RNA - Plasma cells [nTPM]":"3040.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4764.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4968.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2149.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1453.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"146.7","Single Cell Type RNA - Sertoli cells [nTPM]":"3287.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1398.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5423.9","Single Cell Type RNA - Spermatocytes [nTPM]":"133.8","Single Cell Type RNA - Spermatogonia [nTPM]":"381.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4376.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4722.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3257.7","Single Cell Type RNA - T-cells [nTPM]":"5961.7","Single Cell Type RNA - Theca cells [nTPM]":"1688.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1966.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6941.4"},{"Gene":"ADA","Gene synonym":["ADA1"],"Ensembl":"ENSG00000196839","Gene description":"Adenosine deaminase","Uniprot":["P00813"],"Chromosome":"20","Position":"44619522-44652233","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Nucleotide metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant","FDA approved drug targets","Hereditary hemolytic anemia","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"507.2","lymphoid tissue":"259.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"76.4","Extravillous trophoblasts":"128.2","NK-cells":"56.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"168.5","NK-cell":"94.5","non-classical monocyte":"362.8","plasmacytoid DC":"218.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"218.6","monocytes":"362.8","NK-cells":"94.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"JURKAT":"570.9","MOLT-4":"1915.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001399","CAB004307","HPA023884"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004307":"AB_626634","HPA001399":"AB_1078099","HPA023884":"AB_1844573"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.77e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.94e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.6","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"20.2","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"507.2","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"9.0","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"17.8","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"7.0","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"4.4","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"33.4","Tissue RNA - medulla oblongata [nTPM]":"7.2","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"5.3","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"17.9","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"17.5","Tissue RNA - stomach 1 [nTPM]":"46.0","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"259.0","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"6.4","Tissue RNA - tonsil [nTPM]":"26.4","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"8.8","Cell RNA - A-431 [nTPM]":"14.0","Cell RNA - A549 [nTPM]":"37.7","Cell RNA - AF22 [nTPM]":"19.2","Cell RNA - AN3-CA [nTPM]":"13.2","Cell RNA - ASC diff [nTPM]":"35.6","Cell RNA - ASC TERT1 [nTPM]":"48.7","Cell RNA - BEWO [nTPM]":"30.5","Cell RNA - BJ [nTPM]":"13.7","Cell RNA - BJ hTERT+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.3","Cell RNA - CACO-2 [nTPM]":"17.5","Cell RNA - CAPAN-2 [nTPM]":"14.8","Cell RNA - Daudi [nTPM]":"38.4","Cell RNA - EFO-21 [nTPM]":"15.8","Cell RNA - fHDF\/TERT166 [nTPM]":"17.9","Cell RNA - GAMG [nTPM]":"24.7","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"13.2","Cell RNA - HBEC3-KT [nTPM]":"55.1","Cell RNA - HBF TERT88 [nTPM]":"7.3","Cell RNA - HDLM-2 [nTPM]":"2.9","Cell RNA - HEK 293 [nTPM]":"17.2","Cell RNA - HEL [nTPM]":"7.8","Cell RNA - HeLa [nTPM]":"6.6","Cell RNA - Hep G2 [nTPM]":"13.5","Cell RNA - HHSteC [nTPM]":"15.0","Cell RNA - HL-60 [nTPM]":"6.3","Cell RNA - HMC-1 [nTPM]":"20.3","Cell RNA - HSkMC [nTPM]":"234.3","Cell RNA - hTCEpi [nTPM]":"23.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.1","Cell RNA - hTERT-HME1 [nTPM]":"9.0","Cell RNA - hTERT-RPE1 [nTPM]":"12.6","Cell RNA - HUVEC TERT2 [nTPM]":"50.3","Cell RNA - JURKAT [nTPM]":"570.9","Cell RNA - K-562 [nTPM]":"20.4","Cell RNA - Karpas-707 [nTPM]":"30.7","Cell RNA - LHCN-M2 [nTPM]":"6.0","Cell RNA - MCF7 [nTPM]":"33.1","Cell RNA - MOLT-4 [nTPM]":"1915.5","Cell RNA - NB-4 [nTPM]":"28.9","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"17.2","Cell RNA - PC-3 [nTPM]":"13.5","Cell RNA - REH [nTPM]":"102.3","Cell RNA - RH-30 [nTPM]":"25.8","Cell RNA - RPMI-8226 [nTPM]":"95.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"20.2","Cell RNA - SK-BR-3 [nTPM]":"4.4","Cell RNA - SK-MEL-30 [nTPM]":"24.2","Cell RNA - SuSa [nTPM]":"24.0","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"19.1","Cell RNA - TIME [nTPM]":"16.9","Cell RNA - U-138 MG [nTPM]":"10.1","Cell RNA - U-2 OS [nTPM]":"18.6","Cell RNA - U-2197 [nTPM]":"20.5","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"40.1","Cell RNA - U-266\/84 [nTPM]":"27.3","Cell RNA - U-698 [nTPM]":"82.3","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"32.5","Cell RNA - WM-115 [nTPM]":"9.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"9.8","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"43.3","Blood RNA - intermediate monocyte [nTPM]":"168.5","Blood RNA - MAIT T-cell [nTPM]":"27.8","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"35.5","Blood RNA - memory CD8 T-cell [nTPM]":"51.0","Blood RNA - myeloid DC [nTPM]":"35.2","Blood RNA - naive B-cell [nTPM]":"7.6","Blood RNA - naive CD4 T-cell [nTPM]":"27.3","Blood RNA - naive CD8 T-cell [nTPM]":"38.6","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"94.5","Blood RNA - non-classical monocyte [nTPM]":"362.8","Blood RNA - plasmacytoid DC [nTPM]":"218.6","Blood RNA - T-reg [nTPM]":"29.8","Blood RNA - total PBMC [nTPM]":"57.4","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"7.0","Brain RNA - medulla oblongata [nTPM]":"7.2","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"8.8","Single Cell Type RNA - Adipocytes [nTPM]":"18.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"13.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - dendritic cells [nTPM]":"76.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.1","Single Cell Type RNA - Endothelial cells [nTPM]":"17.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"128.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"3.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.8","Single Cell Type RNA - Langerhans cells [nTPM]":"25.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"42.3","Single Cell Type RNA - Macrophages [nTPM]":"27.6","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"37.4","Single Cell Type RNA - Muller glia cells [nTPM]":"3.8","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"31.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"30.9","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"AICDA","Gene synonym":["AID","ARP2","CDA2","HIGM2"],"Ensembl":"ENSG00000111732","Gene description":"Activation induced cytidine deaminase","Uniprot":["Q9GZX7"],"Chromosome":"12","Position":"8602170-8612867","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"lymphoid tissue":"15.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"2.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"0.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"memory B-cell":"1.9","naive B-cell":"3.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"3.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"Daudi":"142.5","U-698":"118.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"15.4","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"142.5","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"19.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"118.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"3.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"AIRE","Gene synonym":["APECED","APS1","PGA1"],"Ensembl":"ENSG00000160224","Gene description":"Autoimmune regulator","Uniprot":["O43918"],"Chromosome":"21","Position":"44285838-44298648","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"brain":"1.6","lymphoid tissue":"1.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"3.1","Excitatory neurons":"1.1","Microglial cells":"1.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"testis cancer":"6.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.29e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AK2","Gene synonym":[],"Ensembl":"ENSG00000004455","Gene description":"Adenylate kinase 2","Uniprot":["P54819"],"Chromosome":"1","Position":"33007940-33080996","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"440.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018479","CAB079913"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB079913":"AB_2546087","HPA018479":"AB_1844676"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.37e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.65e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.40e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"85.3","Tissue RNA - adrenal gland [nTPM]":"88.6","Tissue RNA - amygdala [nTPM]":"39.9","Tissue RNA - appendix [nTPM]":"76.9","Tissue RNA - basal ganglia [nTPM]":"45.0","Tissue RNA - bone marrow [nTPM]":"74.3","Tissue RNA - breast [nTPM]":"80.4","Tissue RNA - cerebellum [nTPM]":"44.1","Tissue RNA - cerebral cortex [nTPM]":"49.0","Tissue RNA - cervix [nTPM]":"79.6","Tissue RNA - choroid plexus [nTPM]":"49.8","Tissue RNA - colon [nTPM]":"117.2","Tissue RNA - duodenum [nTPM]":"140.0","Tissue RNA - endometrium 1 [nTPM]":"58.6","Tissue RNA - epididymis [nTPM]":"52.1","Tissue RNA - esophagus [nTPM]":"108.5","Tissue RNA - fallopian tube [nTPM]":"65.3","Tissue RNA - gallbladder [nTPM]":"49.0","Tissue RNA - heart muscle [nTPM]":"114.1","Tissue RNA - hippocampal formation [nTPM]":"38.8","Tissue RNA - hypothalamus [nTPM]":"43.8","Tissue RNA - kidney [nTPM]":"181.6","Tissue RNA - liver [nTPM]":"172.9","Tissue RNA - lung [nTPM]":"59.3","Tissue RNA - lymph node [nTPM]":"73.3","Tissue RNA - medulla oblongata [nTPM]":"48.5","Tissue RNA - midbrain [nTPM]":"42.8","Tissue RNA - ovary [nTPM]":"59.9","Tissue RNA - pancreas [nTPM]":"78.9","Tissue RNA - parathyroid gland [nTPM]":"123.6","Tissue RNA - pituitary gland [nTPM]":"49.4","Tissue RNA - placenta [nTPM]":"68.4","Tissue RNA - pons [nTPM]":"50.4","Tissue RNA - prostate [nTPM]":"63.2","Tissue RNA - rectum [nTPM]":"114.0","Tissue RNA - retina [nTPM]":"51.0","Tissue RNA - salivary gland [nTPM]":"81.1","Tissue RNA - seminal vesicle [nTPM]":"55.5","Tissue RNA - skeletal muscle [nTPM]":"154.2","Tissue RNA - skin 1 [nTPM]":"74.4","Tissue RNA - small intestine [nTPM]":"139.4","Tissue RNA - smooth muscle [nTPM]":"68.1","Tissue RNA - spinal cord [nTPM]":"44.0","Tissue RNA - spleen [nTPM]":"57.2","Tissue RNA - stomach 1 [nTPM]":"92.7","Tissue RNA - testis [nTPM]":"54.8","Tissue RNA - thalamus [nTPM]":"44.3","Tissue RNA - thymus [nTPM]":"85.9","Tissue RNA - thyroid gland [nTPM]":"86.6","Tissue RNA - tongue [nTPM]":"122.9","Tissue RNA - tonsil [nTPM]":"113.4","Tissue RNA - urinary bladder [nTPM]":"84.2","Tissue RNA - vagina [nTPM]":"76.9","Tissue RNA - white matter [nTPM]":"49.3","Cell RNA - A-431 [nTPM]":"339.1","Cell RNA - A549 [nTPM]":"153.4","Cell RNA - AF22 [nTPM]":"131.6","Cell RNA - AN3-CA [nTPM]":"149.7","Cell RNA - ASC diff [nTPM]":"94.9","Cell RNA - ASC TERT1 [nTPM]":"116.6","Cell RNA - BEWO [nTPM]":"132.8","Cell RNA - BJ [nTPM]":"185.0","Cell RNA - BJ hTERT+ [nTPM]":"143.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"267.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"280.2","Cell RNA - CACO-2 [nTPM]":"283.2","Cell RNA - CAPAN-2 [nTPM]":"311.9","Cell RNA - Daudi [nTPM]":"602.1","Cell RNA - EFO-21 [nTPM]":"218.4","Cell RNA - fHDF\/TERT166 [nTPM]":"139.8","Cell RNA - GAMG [nTPM]":"204.2","Cell RNA - HaCaT [nTPM]":"235.4","Cell RNA - HAP1 [nTPM]":"312.5","Cell RNA - HBEC3-KT [nTPM]":"327.0","Cell RNA - HBF TERT88 [nTPM]":"276.6","Cell RNA - HDLM-2 [nTPM]":"261.6","Cell RNA - HEK 293 [nTPM]":"229.3","Cell RNA - HEL [nTPM]":"396.2","Cell RNA - HeLa [nTPM]":"270.0","Cell RNA - Hep G2 [nTPM]":"219.9","Cell RNA - HHSteC [nTPM]":"218.2","Cell RNA - HL-60 [nTPM]":"712.5","Cell RNA - HMC-1 [nTPM]":"222.2","Cell RNA - HSkMC [nTPM]":"118.1","Cell RNA - hTCEpi [nTPM]":"238.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"232.7","Cell RNA - hTERT-HME1 [nTPM]":"471.2","Cell RNA - hTERT-RPE1 [nTPM]":"163.3","Cell RNA - HUVEC TERT2 [nTPM]":"190.2","Cell RNA - JURKAT [nTPM]":"245.7","Cell RNA - K-562 [nTPM]":"436.9","Cell RNA - Karpas-707 [nTPM]":"230.4","Cell RNA - LHCN-M2 [nTPM]":"165.0","Cell RNA - MCF7 [nTPM]":"174.2","Cell RNA - MOLT-4 [nTPM]":"273.0","Cell RNA - NB-4 [nTPM]":"392.8","Cell RNA - NTERA-2 [nTPM]":"181.2","Cell RNA - OE19 [nTPM]":"337.4","Cell RNA - PC-3 [nTPM]":"222.4","Cell RNA - REH [nTPM]":"314.7","Cell RNA - RH-30 [nTPM]":"222.2","Cell RNA - RPMI-8226 [nTPM]":"415.6","Cell RNA - RPTEC TERT1 [nTPM]":"286.2","Cell RNA - RT4 [nTPM]":"205.1","Cell RNA - SCLC-21H [nTPM]":"190.8","Cell RNA - SH-SY5Y [nTPM]":"114.8","Cell RNA - SiHa [nTPM]":"205.4","Cell RNA - SK-BR-3 [nTPM]":"235.0","Cell RNA - SK-MEL-30 [nTPM]":"584.8","Cell RNA - SuSa [nTPM]":"151.4","Cell RNA - T-47d [nTPM]":"194.5","Cell RNA - THP-1 [nTPM]":"517.2","Cell RNA - TIME [nTPM]":"138.9","Cell RNA - U-138 MG [nTPM]":"165.5","Cell RNA - U-2 OS [nTPM]":"194.3","Cell RNA - U-2197 [nTPM]":"259.4","Cell RNA - U-251 MG [nTPM]":"357.5","Cell RNA - U-266\/70 [nTPM]":"238.0","Cell RNA - U-266\/84 [nTPM]":"324.7","Cell RNA - U-698 [nTPM]":"565.7","Cell RNA - U-87 MG [nTPM]":"232.4","Cell RNA - U-937 [nTPM]":"664.6","Cell RNA - WM-115 [nTPM]":"195.5","Blood RNA - basophil [nTPM]":"49.2","Blood RNA - classical monocyte [nTPM]":"158.8","Blood RNA - eosinophil [nTPM]":"198.0","Blood RNA - gdT-cell [nTPM]":"77.1","Blood RNA - intermediate monocyte [nTPM]":"145.5","Blood RNA - MAIT T-cell [nTPM]":"81.8","Blood RNA - memory B-cell [nTPM]":"122.3","Blood RNA - memory CD4 T-cell [nTPM]":"72.7","Blood RNA - memory CD8 T-cell [nTPM]":"74.0","Blood RNA - myeloid DC [nTPM]":"195.8","Blood RNA - naive B-cell [nTPM]":"105.8","Blood RNA - naive CD4 T-cell [nTPM]":"72.9","Blood RNA - naive CD8 T-cell [nTPM]":"67.9","Blood RNA - neutrophil [nTPM]":"42.1","Blood RNA - NK-cell [nTPM]":"115.3","Blood RNA - non-classical monocyte [nTPM]":"130.4","Blood RNA - plasmacytoid DC [nTPM]":"154.2","Blood RNA - T-reg [nTPM]":"96.8","Blood RNA - total PBMC [nTPM]":"188.1","Brain RNA - amygdala [nTPM]":"39.9","Brain RNA - basal ganglia [nTPM]":"45.0","Brain RNA - cerebellum [nTPM]":"44.1","Brain RNA - cerebral cortex [nTPM]":"49.0","Brain RNA - hippocampal formation [nTPM]":"38.8","Brain RNA - hypothalamus [nTPM]":"43.8","Brain RNA - medulla oblongata [nTPM]":"48.5","Brain RNA - midbrain [nTPM]":"42.8","Brain RNA - pons [nTPM]":"50.4","Brain RNA - spinal cord [nTPM]":"44.0","Brain RNA - thalamus [nTPM]":"44.3","Brain RNA - white matter [nTPM]":"49.3","Single Cell Type RNA - Adipocytes [nTPM]":"60.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"79.0","Single Cell Type RNA - Astrocytes [nTPM]":"19.6","Single Cell Type RNA - B-cells [nTPM]":"44.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"125.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"101.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"228.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"63.7","Single Cell Type RNA - Bipolar cells [nTPM]":"21.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"66.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"72.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"106.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"71.4","Single Cell Type RNA - Club cells [nTPM]":"142.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"112.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"83.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"158.0","Single Cell Type RNA - dendritic cells [nTPM]":"37.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"109.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"256.3","Single Cell Type RNA - Ductal cells [nTPM]":"120.2","Single Cell Type RNA - Early spermatids [nTPM]":"108.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.1","Single Cell Type RNA - Endothelial cells [nTPM]":"70.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.4","Single Cell Type RNA - Erythroid cells [nTPM]":"50.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"123.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"164.6","Single Cell Type RNA - Fibroblasts [nTPM]":"58.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"66.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.0","Single Cell Type RNA - granulocytes [nTPM]":"40.0","Single Cell Type RNA - Granulosa cells [nTPM]":"38.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.4","Single Cell Type RNA - Hepatocytes [nTPM]":"135.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"96.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"84.7","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"44.8","Single Cell Type RNA - Langerhans cells [nTPM]":"60.1","Single Cell Type RNA - Late spermatids [nTPM]":"42.8","Single Cell Type RNA - Leydig cells [nTPM]":"46.9","Single Cell Type RNA - Macrophages [nTPM]":"48.4","Single Cell Type RNA - Melanocytes [nTPM]":"87.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"67.3","Single Cell Type RNA - Muller glia cells [nTPM]":"22.1","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"110.5","Single Cell Type RNA - Paneth cells [nTPM]":"67.2","Single Cell Type RNA - Peritubular cells [nTPM]":"44.0","Single Cell Type RNA - Plasma cells [nTPM]":"55.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"109.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"236.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"440.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"67.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.8","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"108.4","Single Cell Type RNA - Spermatocytes [nTPM]":"91.0","Single Cell Type RNA - Spermatogonia [nTPM]":"31.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"88.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"122.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"216.6","Single Cell Type RNA - T-cells [nTPM]":"40.7","Single Cell Type RNA - Theca cells [nTPM]":"72.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"122.6","Single Cell Type RNA - Urothelial cells [nTPM]":"120.5"},{"Gene":"ATM","Gene synonym":["ATA","ATC","ATD","ATDC","TEL1","TELO1"],"Ensembl":"ENSG00000149311","Gene description":"ATM serine\/threonine kinase","Uniprot":["Q13315"],"Chromosome":"11","Position":"108222832-108369102","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"210.6","NK-cells":"339.8","Oligodendrocytes":"217.6","Rod photoreceptor cells":"200.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"78.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000102","HPA067142"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000102":null,"HPA067142":"AB_2685789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"33.7","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"20.6","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"20.2","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"18.5","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"23.7","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.0","Cell RNA - U-698 [nTPM]":"78.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"16.5","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"62.7","Single Cell Type RNA - B-cells [nTPM]":"146.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"111.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.9","Single Cell Type RNA - dendritic cells [nTPM]":"140.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"96.4","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"69.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"178.9","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"339.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"96.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.2","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"147.7","Single Cell Type RNA - Theca cells [nTPM]":"52.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"BCL10","Gene synonym":["c-E10","CARMEN","CIPER","CLAP","mE10"],"Ensembl":"ENSG00000142867","Gene description":"BCL10 immune signaling adaptor","Uniprot":["O95999"],"Chromosome":"1","Position":"85265776-85276632","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Apoptosis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"194.1","Paneth cells":"210.2","Urothelial cells":"297.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"97.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001944","HPA017925"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB001944":null,"HPA017925":"AB_1845312"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.51e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.21e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"13.8","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"24.3","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"5.3","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"14.7","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"26.7","Tissue RNA - duodenum [nTPM]":"14.7","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"7.9","Tissue RNA - esophagus [nTPM]":"18.1","Tissue RNA - fallopian tube [nTPM]":"9.0","Tissue RNA - gallbladder [nTPM]":"18.9","Tissue RNA - heart muscle [nTPM]":"5.5","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"8.7","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"13.7","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"7.2","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"4.4","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"23.5","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"16.5","Tissue RNA - smooth muscle [nTPM]":"11.8","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"11.6","Tissue RNA - stomach 1 [nTPM]":"14.9","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"5.8","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"5.7","Tissue RNA - tonsil [nTPM]":"16.4","Tissue RNA - urinary bladder [nTPM]":"23.1","Tissue RNA - vagina [nTPM]":"11.3","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"38.5","Cell RNA - A549 [nTPM]":"7.6","Cell RNA - AF22 [nTPM]":"11.6","Cell RNA - AN3-CA [nTPM]":"11.8","Cell RNA - ASC diff [nTPM]":"13.7","Cell RNA - ASC TERT1 [nTPM]":"23.7","Cell RNA - BEWO [nTPM]":"16.9","Cell RNA - BJ [nTPM]":"26.8","Cell RNA - BJ hTERT+ [nTPM]":"27.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.8","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"14.5","Cell RNA - Daudi [nTPM]":"14.5","Cell RNA - EFO-21 [nTPM]":"19.1","Cell RNA - fHDF\/TERT166 [nTPM]":"22.5","Cell RNA - GAMG [nTPM]":"39.3","Cell RNA - HaCaT [nTPM]":"19.6","Cell RNA - HAP1 [nTPM]":"12.8","Cell RNA - HBEC3-KT [nTPM]":"32.4","Cell RNA - HBF TERT88 [nTPM]":"28.7","Cell RNA - HDLM-2 [nTPM]":"14.8","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"16.9","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"24.0","Cell RNA - HL-60 [nTPM]":"16.7","Cell RNA - HMC-1 [nTPM]":"15.4","Cell RNA - HSkMC [nTPM]":"18.6","Cell RNA - hTCEpi [nTPM]":"31.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.4","Cell RNA - hTERT-HME1 [nTPM]":"25.6","Cell RNA - hTERT-RPE1 [nTPM]":"24.5","Cell RNA - HUVEC TERT2 [nTPM]":"97.9","Cell RNA - JURKAT [nTPM]":"10.0","Cell RNA - K-562 [nTPM]":"11.7","Cell RNA - Karpas-707 [nTPM]":"14.1","Cell RNA - LHCN-M2 [nTPM]":"33.2","Cell RNA - MCF7 [nTPM]":"6.8","Cell RNA - MOLT-4 [nTPM]":"16.4","Cell RNA - NB-4 [nTPM]":"13.5","Cell RNA - NTERA-2 [nTPM]":"19.0","Cell RNA - OE19 [nTPM]":"22.1","Cell RNA - PC-3 [nTPM]":"25.0","Cell RNA - REH [nTPM]":"12.2","Cell RNA - RH-30 [nTPM]":"21.8","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"71.2","Cell RNA - RT4 [nTPM]":"29.2","Cell RNA - SCLC-21H [nTPM]":"6.3","Cell RNA - SH-SY5Y [nTPM]":"8.5","Cell RNA - SiHa [nTPM]":"8.2","Cell RNA - SK-BR-3 [nTPM]":"28.6","Cell RNA - SK-MEL-30 [nTPM]":"23.2","Cell RNA - SuSa [nTPM]":"14.8","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"10.2","Cell RNA - TIME [nTPM]":"47.3","Cell RNA - U-138 MG [nTPM]":"19.0","Cell RNA - U-2 OS [nTPM]":"13.2","Cell RNA - U-2197 [nTPM]":"24.1","Cell RNA - U-251 MG [nTPM]":"27.5","Cell RNA - U-266\/70 [nTPM]":"11.7","Cell RNA - U-266\/84 [nTPM]":"6.5","Cell RNA - U-698 [nTPM]":"16.6","Cell RNA - U-87 MG [nTPM]":"9.9","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"78.4","Blood RNA - classical monocyte [nTPM]":"34.1","Blood RNA - eosinophil [nTPM]":"48.2","Blood RNA - gdT-cell [nTPM]":"20.8","Blood RNA - intermediate monocyte [nTPM]":"41.8","Blood RNA - MAIT T-cell [nTPM]":"23.5","Blood RNA - memory B-cell [nTPM]":"46.7","Blood RNA - memory CD4 T-cell [nTPM]":"27.0","Blood RNA - memory CD8 T-cell [nTPM]":"24.4","Blood RNA - myeloid DC [nTPM]":"33.7","Blood RNA - naive B-cell [nTPM]":"41.4","Blood RNA - naive CD4 T-cell [nTPM]":"24.7","Blood RNA - naive CD8 T-cell [nTPM]":"23.5","Blood RNA - neutrophil [nTPM]":"85.0","Blood RNA - NK-cell [nTPM]":"24.6","Blood RNA - non-classical monocyte [nTPM]":"33.1","Blood RNA - plasmacytoid DC [nTPM]":"26.3","Blood RNA - T-reg [nTPM]":"31.1","Blood RNA - total PBMC [nTPM]":"22.9","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"5.3","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"4.4","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"5.8","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"40.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"49.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"194.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"167.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.3","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"54.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"174.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"71.5","Single Cell Type RNA - Early spermatids [nTPM]":"85.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"97.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.1","Single Cell Type RNA - Endothelial cells [nTPM]":"48.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"49.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.4","Single Cell Type RNA - Fibroblasts [nTPM]":"24.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"57.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"152.2","Single Cell Type RNA - granulocytes [nTPM]":"39.3","Single Cell Type RNA - Granulosa cells [nTPM]":"17.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"19.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.2","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"79.7","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"31.8","Single Cell Type RNA - Langerhans cells [nTPM]":"68.8","Single Cell Type RNA - Late spermatids [nTPM]":"13.4","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"41.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"21.7","Single Cell Type RNA - Muller glia cells [nTPM]":"11.1","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.1","Single Cell Type RNA - Paneth cells [nTPM]":"210.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"25.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"80.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.8","Single Cell Type RNA - Spermatocytes [nTPM]":"9.7","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"76.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"171.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - T-cells [nTPM]":"31.3","Single Cell Type RNA - Theca cells [nTPM]":"21.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.2","Single Cell Type RNA - Urothelial cells [nTPM]":"297.4"},{"Gene":"BLM","Gene synonym":["BS","RECQ2","RECQL3"],"Ensembl":"ENSG00000197299","Gene description":"BLM RecQ like helicase","Uniprot":["P54132"],"Chromosome":"15","Position":"90717346-90816166","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.7","lymphoid tissue":"7.9","salivary gland":"7.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"18.3","Oligodendrocyte precursor cells":"58.3","Plasma cells":"20.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005689"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA005689":"AB_1845372"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"13.0","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"12.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"14.6","Cell RNA - BJ [nTPM]":"9.4","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.4","Cell RNA - CACO-2 [nTPM]":"11.7","Cell RNA - CAPAN-2 [nTPM]":"10.1","Cell RNA - Daudi [nTPM]":"35.1","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.6","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"25.7","Cell RNA - HBEC3-KT [nTPM]":"7.1","Cell RNA - HBF TERT88 [nTPM]":"15.1","Cell RNA - HDLM-2 [nTPM]":"19.1","Cell RNA - HEK 293 [nTPM]":"20.5","Cell RNA - HEL [nTPM]":"36.4","Cell RNA - HeLa [nTPM]":"14.8","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"33.7","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.6","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"7.9","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"32.7","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"7.4","Cell RNA - MOLT-4 [nTPM]":"28.3","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"22.2","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"25.4","Cell RNA - RH-30 [nTPM]":"39.1","Cell RNA - RPMI-8226 [nTPM]":"14.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"18.9","Cell RNA - SCLC-21H [nTPM]":"14.6","Cell RNA - SH-SY5Y [nTPM]":"14.7","Cell RNA - SiHa [nTPM]":"8.5","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"18.1","Cell RNA - T-47d [nTPM]":"7.2","Cell RNA - THP-1 [nTPM]":"23.4","Cell RNA - TIME [nTPM]":"3.7","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"21.0","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"39.5","Cell RNA - U-87 MG [nTPM]":"5.6","Cell RNA - U-937 [nTPM]":"25.8","Cell RNA - WM-115 [nTPM]":"15.7","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.9","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"20.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"17.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"10.2","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"BLNK","Gene synonym":["BASH","bca","BLNK-s","Ly57","SLP-65","SLP65"],"Ensembl":"ENSG00000095585","Gene description":"B cell linker","Uniprot":["Q8WV28"],"Chromosome":"10","Position":"96189171-96271587","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["B-cell activation"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"70.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"94.2","dendritic cells":"64.0","Microglial cells":"157.4","Plasma cells":"80.4","Proximal enterocytes":"64.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"memory B-cell":"161.2","naive B-cell":"140.5","plasmacytoid DC":"231.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"101","RNA blood lineage specific nTPM":{"B-cells":"161.2","dendritic cells":"231.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Daudi":"68.7","REH":"168.4","RPMI-8226":"94.4","U-698":"251.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009333","CAB016291","HPA038309","HPA038310"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009333":"AB_2290422","CAB016291":"AB_626752","HPA038309":"AB_2675945","HPA038310":"AB_2675946"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.67e-6"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"27.5","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"10.1","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"13.9","Tissue RNA - colon [nTPM]":"16.9","Tissue RNA - duodenum [nTPM]":"38.9","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"30.1","Tissue RNA - esophagus [nTPM]":"39.9","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"10.8","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"28.5","Tissue RNA - liver [nTPM]":"39.2","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"57.6","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"4.0","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"17.4","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"18.2","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"13.2","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"8.0","Tissue RNA - small intestine [nTPM]":"34.0","Tissue RNA - smooth muscle [nTPM]":"3.0","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"54.0","Tissue RNA - stomach 1 [nTPM]":"29.2","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"11.6","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"70.5","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"15.8","Tissue RNA - white matter [nTPM]":"5.2","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"68.7","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"8.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"168.4","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"94.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"13.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"15.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"23.7","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"251.4","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"161.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"20.6","Blood RNA - naive B-cell [nTPM]":"140.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"231.5","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"8.1","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"4.0","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"5.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"94.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"64.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"27.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.4","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"18.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"157.4","Single Cell Type RNA - monocytes [nTPM]":"4.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.4","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"80.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"64.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"41.5","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.5","Single Cell Type RNA - Urothelial cells [nTPM]":"23.8"},{"Gene":"BTK","Gene synonym":["AGMX1","ATK","IMD1","PSCTK1","XLA"],"Ensembl":"ENSG00000010671","Gene description":"Bruton tyrosine kinase","Uniprot":["Q06187"],"Chromosome":"X","Position":"101349447-101390796","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Apoptosis","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"32.6","lymphoid tissue":"78.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"84.7","granulocytes":"211.4","Hofbauer cells":"56.6","Kupffer cells":"63.5","Macrophages":"61.1","monocytes":"71.1","Plasma cells":"43.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"557.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"557.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"206.7","HEL":"287.4","HMC-1":"990.3","U-937":"149.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001198","HPA002028","CAB016689"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2300000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB016689":"AB_1611894","HPA001198":"AB_1078305","HPA002028":"AB_1078306"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"30.7","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"32.6","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"3.9","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"6.6","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"7.6","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"19.6","Tissue RNA - lymph node [nTPM]":"55.5","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"38.4","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"2.0","Tissue RNA - tonsil [nTPM]":"78.0","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"206.7","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"287.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"116.7","Cell RNA - HMC-1 [nTPM]":"990.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"61.9","Cell RNA - Karpas-707 [nTPM]":"2.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"81.5","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"87.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"13.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"68.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"2.6","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"98.3","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"149.8","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"557.5","Blood RNA - classical monocyte [nTPM]":"62.2","Blood RNA - eosinophil [nTPM]":"110.5","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"99.9","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"72.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"72.7","Blood RNA - naive B-cell [nTPM]":"73.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"24.7","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"123.9","Blood RNA - plasmacytoid DC [nTPM]":"33.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"38.4","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"84.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"211.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"56.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"63.5","Single Cell Type RNA - Langerhans cells [nTPM]":"31.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"61.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"71.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"43.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"5.7","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"C1QA","Gene synonym":[],"Ensembl":"ENSG00000173372","Gene description":"Complement C1q A chain","Uniprot":["P02745"],"Chromosome":"1","Position":"22636628-22639678","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1092.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hofbauer cells":"1663.2","Kupffer cells":"5007.4","Macrophages":"1874.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"39","RNA blood cell specific nTPM":{"intermediate monocyte":"226.1","non-classical monocyte":"181.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"60","RNA blood lineage specific nTPM":{"monocytes":"226.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"2.3","NB-4":"1.4","RPMI-8226":"7.1","SCLC-21H":"3.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002350","CAB009823"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009823":"AB_2228238","HPA002350":"AB_1078552"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"375.1","Tissue RNA - adrenal gland [nTPM]":"235.6","Tissue RNA - amygdala [nTPM]":"86.6","Tissue RNA - appendix [nTPM]":"134.0","Tissue RNA - basal ganglia [nTPM]":"85.6","Tissue RNA - bone marrow [nTPM]":"53.9","Tissue RNA - breast [nTPM]":"95.9","Tissue RNA - cerebellum [nTPM]":"85.8","Tissue RNA - cerebral cortex [nTPM]":"135.3","Tissue RNA - cervix [nTPM]":"75.8","Tissue RNA - choroid plexus [nTPM]":"120.0","Tissue RNA - colon [nTPM]":"142.8","Tissue RNA - duodenum [nTPM]":"172.3","Tissue RNA - endometrium 1 [nTPM]":"43.1","Tissue RNA - epididymis [nTPM]":"26.0","Tissue RNA - esophagus [nTPM]":"58.3","Tissue RNA - fallopian tube [nTPM]":"75.6","Tissue RNA - gallbladder [nTPM]":"172.4","Tissue RNA - heart muscle [nTPM]":"74.8","Tissue RNA - hippocampal formation [nTPM]":"82.9","Tissue RNA - hypothalamus [nTPM]":"93.7","Tissue RNA - kidney [nTPM]":"56.2","Tissue RNA - liver [nTPM]":"208.8","Tissue RNA - lung [nTPM]":"404.3","Tissue RNA - lymph node [nTPM]":"532.3","Tissue RNA - medulla oblongata [nTPM]":"126.7","Tissue RNA - midbrain [nTPM]":"110.1","Tissue RNA - ovary [nTPM]":"37.5","Tissue RNA - pancreas [nTPM]":"34.3","Tissue RNA - parathyroid gland [nTPM]":"26.2","Tissue RNA - pituitary gland [nTPM]":"46.3","Tissue RNA - placenta [nTPM]":"256.3","Tissue RNA - pons [nTPM]":"110.3","Tissue RNA - prostate [nTPM]":"47.1","Tissue RNA - rectum [nTPM]":"120.2","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"48.1","Tissue RNA - seminal vesicle [nTPM]":"54.6","Tissue RNA - skeletal muscle [nTPM]":"14.8","Tissue RNA - skin 1 [nTPM]":"21.8","Tissue RNA - small intestine [nTPM]":"190.1","Tissue RNA - smooth muscle [nTPM]":"195.0","Tissue RNA - spinal cord [nTPM]":"107.5","Tissue RNA - spleen [nTPM]":"1092.6","Tissue RNA - stomach 1 [nTPM]":"90.8","Tissue RNA - testis [nTPM]":"38.2","Tissue RNA - thalamus [nTPM]":"109.4","Tissue RNA - thymus [nTPM]":"100.3","Tissue RNA - thyroid gland [nTPM]":"36.5","Tissue RNA - tongue [nTPM]":"49.3","Tissue RNA - tonsil [nTPM]":"68.0","Tissue RNA - urinary bladder [nTPM]":"257.5","Tissue RNA - vagina [nTPM]":"30.4","Tissue RNA - white matter [nTPM]":"131.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.0","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"226.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"181.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"86.6","Brain RNA - basal ganglia [nTPM]":"85.6","Brain RNA - cerebellum [nTPM]":"85.8","Brain RNA - cerebral cortex [nTPM]":"135.3","Brain RNA - hippocampal formation [nTPM]":"82.9","Brain RNA - hypothalamus [nTPM]":"93.7","Brain RNA - medulla oblongata [nTPM]":"126.7","Brain RNA - midbrain [nTPM]":"110.1","Brain RNA - pons [nTPM]":"110.3","Brain RNA - spinal cord [nTPM]":"107.5","Brain RNA - thalamus [nTPM]":"109.4","Brain RNA - white matter [nTPM]":"131.6","Single Cell Type RNA - Adipocytes [nTPM]":"17.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"55.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"19.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"18.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"46.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"41.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"76.1","Single Cell Type RNA - Hepatocytes [nTPM]":"26.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1663.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5007.4","Single Cell Type RNA - Langerhans cells [nTPM]":"291.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.9","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"1874.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"16.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - T-cells [nTPM]":"11.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"C1QB","Gene synonym":[],"Ensembl":"ENSG00000173369","Gene description":"Complement C1q B chain","Uniprot":[],"Chromosome":"1","Position":"22652762-22661637","Protein class":["Human disease related genes","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"546.4","lymphoid tissue":"990.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"28","RNA single cell type specific nTPM":{"Hofbauer cells":"1451.0","Kupffer cells":"4559.7","Macrophages":"1747.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"71","RNA blood cell specific nTPM":{"intermediate monocyte":"140.6","non-classical monocyte":"101.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"85","RNA blood lineage specific nTPM":{"monocytes":"140.6"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052116"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052116":"AB_2681735"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"439.2","Tissue RNA - adrenal gland [nTPM]":"229.0","Tissue RNA - amygdala [nTPM]":"95.8","Tissue RNA - appendix [nTPM]":"149.4","Tissue RNA - basal ganglia [nTPM]":"94.2","Tissue RNA - bone marrow [nTPM]":"53.5","Tissue RNA - breast [nTPM]":"87.1","Tissue RNA - cerebellum [nTPM]":"97.2","Tissue RNA - cerebral cortex [nTPM]":"148.7","Tissue RNA - cervix [nTPM]":"65.4","Tissue RNA - choroid plexus [nTPM]":"132.6","Tissue RNA - colon [nTPM]":"162.0","Tissue RNA - duodenum [nTPM]":"186.0","Tissue RNA - endometrium 1 [nTPM]":"27.7","Tissue RNA - epididymis [nTPM]":"26.4","Tissue RNA - esophagus [nTPM]":"63.0","Tissue RNA - fallopian tube [nTPM]":"50.5","Tissue RNA - gallbladder [nTPM]":"194.9","Tissue RNA - heart muscle [nTPM]":"62.6","Tissue RNA - hippocampal formation [nTPM]":"89.8","Tissue RNA - hypothalamus [nTPM]":"107.7","Tissue RNA - kidney [nTPM]":"18.3","Tissue RNA - liver [nTPM]":"243.4","Tissue RNA - lung [nTPM]":"546.4","Tissue RNA - lymph node [nTPM]":"514.6","Tissue RNA - medulla oblongata [nTPM]":"161.0","Tissue RNA - midbrain [nTPM]":"143.3","Tissue RNA - ovary [nTPM]":"39.6","Tissue RNA - pancreas [nTPM]":"40.0","Tissue RNA - parathyroid gland [nTPM]":"28.5","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"249.2","Tissue RNA - pons [nTPM]":"138.4","Tissue RNA - prostate [nTPM]":"28.0","Tissue RNA - rectum [nTPM]":"146.0","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"44.9","Tissue RNA - seminal vesicle [nTPM]":"51.2","Tissue RNA - skeletal muscle [nTPM]":"5.3","Tissue RNA - skin 1 [nTPM]":"6.1","Tissue RNA - small intestine [nTPM]":"186.1","Tissue RNA - smooth muscle [nTPM]":"261.4","Tissue RNA - spinal cord [nTPM]":"138.2","Tissue RNA - spleen [nTPM]":"990.2","Tissue RNA - stomach 1 [nTPM]":"88.0","Tissue RNA - testis [nTPM]":"39.9","Tissue RNA - thalamus [nTPM]":"142.2","Tissue RNA - thymus [nTPM]":"72.0","Tissue RNA - thyroid gland [nTPM]":"23.6","Tissue RNA - tongue [nTPM]":"38.6","Tissue RNA - tonsil [nTPM]":"58.4","Tissue RNA - urinary bladder [nTPM]":"255.8","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"185.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"140.6","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"101.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"95.8","Brain RNA - basal ganglia [nTPM]":"94.2","Brain RNA - cerebellum [nTPM]":"97.2","Brain RNA - cerebral cortex [nTPM]":"148.7","Brain RNA - hippocampal formation [nTPM]":"89.8","Brain RNA - hypothalamus [nTPM]":"107.7","Brain RNA - medulla oblongata [nTPM]":"161.0","Brain RNA - midbrain [nTPM]":"143.3","Brain RNA - pons [nTPM]":"138.4","Brain RNA - spinal cord [nTPM]":"138.2","Brain RNA - thalamus [nTPM]":"142.2","Brain RNA - white matter [nTPM]":"185.8","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"17.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"65.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"32.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.6","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.1","Single Cell Type RNA - Hepatocytes [nTPM]":"26.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1451.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4559.7","Single Cell Type RNA - Langerhans cells [nTPM]":"92.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"1747.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - T-cells [nTPM]":"6.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"C1QC","Gene synonym":["C1QG"],"Ensembl":"ENSG00000159189","Gene description":"Complement C1q C chain","Uniprot":["P02747"],"Chromosome":"1","Position":"22643633-22648110","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"950.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Hofbauer cells":"1356.5","Kupffer cells":"2134.6","Macrophages":"1040.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"intermediate monocyte":"57.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"541","RNA blood lineage specific nTPM":{"monocytes":"57.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"1.0","RPMI-8226":"2.6","U-266\/70":"1.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001471","CAB009828"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":513000000,"Blood concentration - Conc. blood MS [pg\/L]":"2100000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009828":"AB_2067541","HPA001471":"AB_1078553"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"285.2","Tissue RNA - adrenal gland [nTPM]":"196.0","Tissue RNA - amygdala [nTPM]":"60.1","Tissue RNA - appendix [nTPM]":"159.7","Tissue RNA - basal ganglia [nTPM]":"58.6","Tissue RNA - bone marrow [nTPM]":"43.5","Tissue RNA - breast [nTPM]":"70.5","Tissue RNA - cerebellum [nTPM]":"64.8","Tissue RNA - cerebral cortex [nTPM]":"97.1","Tissue RNA - cervix [nTPM]":"51.9","Tissue RNA - choroid plexus [nTPM]":"90.6","Tissue RNA - colon [nTPM]":"133.2","Tissue RNA - duodenum [nTPM]":"179.9","Tissue RNA - endometrium 1 [nTPM]":"36.3","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"55.3","Tissue RNA - fallopian tube [nTPM]":"67.4","Tissue RNA - gallbladder [nTPM]":"155.4","Tissue RNA - heart muscle [nTPM]":"58.6","Tissue RNA - hippocampal formation [nTPM]":"54.9","Tissue RNA - hypothalamus [nTPM]":"75.5","Tissue RNA - kidney [nTPM]":"41.2","Tissue RNA - liver [nTPM]":"169.6","Tissue RNA - lung [nTPM]":"290.8","Tissue RNA - lymph node [nTPM]":"370.2","Tissue RNA - medulla oblongata [nTPM]":"124.7","Tissue RNA - midbrain [nTPM]":"105.4","Tissue RNA - ovary [nTPM]":"32.1","Tissue RNA - pancreas [nTPM]":"37.5","Tissue RNA - parathyroid gland [nTPM]":"22.1","Tissue RNA - pituitary gland [nTPM]":"39.6","Tissue RNA - placenta [nTPM]":"204.9","Tissue RNA - pons [nTPM]":"105.0","Tissue RNA - prostate [nTPM]":"37.8","Tissue RNA - rectum [nTPM]":"91.3","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"51.6","Tissue RNA - seminal vesicle [nTPM]":"44.5","Tissue RNA - skeletal muscle [nTPM]":"12.9","Tissue RNA - skin 1 [nTPM]":"18.3","Tissue RNA - small intestine [nTPM]":"195.7","Tissue RNA - smooth muscle [nTPM]":"164.7","Tissue RNA - spinal cord [nTPM]":"100.4","Tissue RNA - spleen [nTPM]":"950.7","Tissue RNA - stomach 1 [nTPM]":"94.8","Tissue RNA - testis [nTPM]":"33.9","Tissue RNA - thalamus [nTPM]":"106.0","Tissue RNA - thymus [nTPM]":"75.7","Tissue RNA - thyroid gland [nTPM]":"29.2","Tissue RNA - tongue [nTPM]":"31.8","Tissue RNA - tonsil [nTPM]":"50.7","Tissue RNA - urinary bladder [nTPM]":"191.8","Tissue RNA - vagina [nTPM]":"24.6","Tissue RNA - white matter [nTPM]":"159.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"2.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"57.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"10.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"60.1","Brain RNA - basal ganglia [nTPM]":"58.6","Brain RNA - cerebellum [nTPM]":"64.8","Brain RNA - cerebral cortex [nTPM]":"97.1","Brain RNA - hippocampal formation [nTPM]":"54.9","Brain RNA - hypothalamus [nTPM]":"75.5","Brain RNA - medulla oblongata [nTPM]":"124.7","Brain RNA - midbrain [nTPM]":"105.4","Brain RNA - pons [nTPM]":"105.0","Brain RNA - spinal cord [nTPM]":"100.4","Brain RNA - thalamus [nTPM]":"106.0","Brain RNA - white matter [nTPM]":"159.3","Single Cell Type RNA - Adipocytes [nTPM]":"13.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"34.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.5","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"6.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"1356.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2134.6","Single Cell Type RNA - Langerhans cells [nTPM]":"202.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"1040.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"23.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.9","Single Cell Type RNA - T-cells [nTPM]":"3.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"C1R","Gene synonym":[],"Ensembl":"ENSG00000159403","Gene description":"Complement C1r","Uniprot":[],"Chromosome":"12","Position":"7080214-7092540","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"1425.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"442.3","Fibroblasts":"684.4","Hepatocytes":"1444.2","Leydig cells":"1142.6","Peritubular cells":"388.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1089.8","ASC TERT1":"546.0","BJ hTERT+":"461.9","BJ hTERT+ SV40 Large T+ RasG12V":"303.4","HSkMC":"672.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001251","HPA001551"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001251":"AB_2666252","HPA001551":"AB_10754818"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.94e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"540.6","Tissue RNA - adrenal gland [nTPM]":"203.6","Tissue RNA - amygdala [nTPM]":"15.8","Tissue RNA - appendix [nTPM]":"122.4","Tissue RNA - basal ganglia [nTPM]":"15.9","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"400.6","Tissue RNA - cerebellum [nTPM]":"15.9","Tissue RNA - cerebral cortex [nTPM]":"23.3","Tissue RNA - cervix [nTPM]":"470.5","Tissue RNA - choroid plexus [nTPM]":"21.7","Tissue RNA - colon [nTPM]":"277.3","Tissue RNA - duodenum [nTPM]":"38.3","Tissue RNA - endometrium 1 [nTPM]":"353.8","Tissue RNA - epididymis [nTPM]":"80.8","Tissue RNA - esophagus [nTPM]":"119.0","Tissue RNA - fallopian tube [nTPM]":"526.3","Tissue RNA - gallbladder [nTPM]":"279.1","Tissue RNA - heart muscle [nTPM]":"458.7","Tissue RNA - hippocampal formation [nTPM]":"15.4","Tissue RNA - hypothalamus [nTPM]":"19.6","Tissue RNA - kidney [nTPM]":"148.9","Tissue RNA - liver [nTPM]":"1425.6","Tissue RNA - lung [nTPM]":"340.3","Tissue RNA - lymph node [nTPM]":"72.4","Tissue RNA - medulla oblongata [nTPM]":"23.4","Tissue RNA - midbrain [nTPM]":"19.9","Tissue RNA - ovary [nTPM]":"644.3","Tissue RNA - pancreas [nTPM]":"88.0","Tissue RNA - parathyroid gland [nTPM]":"11.0","Tissue RNA - pituitary gland [nTPM]":"63.9","Tissue RNA - placenta [nTPM]":"52.4","Tissue RNA - pons [nTPM]":"18.4","Tissue RNA - prostate [nTPM]":"205.2","Tissue RNA - rectum [nTPM]":"100.9","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"158.3","Tissue RNA - seminal vesicle [nTPM]":"87.0","Tissue RNA - skeletal muscle [nTPM]":"69.4","Tissue RNA - skin 1 [nTPM]":"177.7","Tissue RNA - small intestine [nTPM]":"228.1","Tissue RNA - smooth muscle [nTPM]":"157.7","Tissue RNA - spinal cord [nTPM]":"18.1","Tissue RNA - spleen [nTPM]":"192.1","Tissue RNA - stomach 1 [nTPM]":"242.7","Tissue RNA - testis [nTPM]":"46.7","Tissue RNA - thalamus [nTPM]":"18.1","Tissue RNA - thymus [nTPM]":"34.7","Tissue RNA - thyroid gland [nTPM]":"223.4","Tissue RNA - tongue [nTPM]":"74.2","Tissue RNA - tonsil [nTPM]":"75.3","Tissue RNA - urinary bladder [nTPM]":"468.4","Tissue RNA - vagina [nTPM]":"394.3","Tissue RNA - white matter [nTPM]":"18.0","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"9.1","Cell RNA - ASC diff [nTPM]":"1089.8","Cell RNA - ASC TERT1 [nTPM]":"546.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"108.9","Cell RNA - BJ hTERT+ [nTPM]":"461.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"143.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"303.4","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"108.8","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"2.3","Cell RNA - HAP1 [nTPM]":"11.8","Cell RNA - HBEC3-KT [nTPM]":"5.5","Cell RNA - HBF TERT88 [nTPM]":"18.3","Cell RNA - HDLM-2 [nTPM]":"18.3","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"4.1","Cell RNA - Hep G2 [nTPM]":"3.6","Cell RNA - HHSteC [nTPM]":"226.5","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"672.1","Cell RNA - hTCEpi [nTPM]":"3.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"74.7","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"121.0","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"20.5","Cell RNA - LHCN-M2 [nTPM]":"21.2","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"8.0","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"8.6","Cell RNA - RH-30 [nTPM]":"3.8","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"2.3","Cell RNA - SiHa [nTPM]":"95.1","Cell RNA - SK-BR-3 [nTPM]":"3.7","Cell RNA - SK-MEL-30 [nTPM]":"2.8","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"38.3","Cell RNA - U-2 OS [nTPM]":"6.3","Cell RNA - U-2197 [nTPM]":"152.1","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"53.1","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"5.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"15.8","Brain RNA - basal ganglia [nTPM]":"15.9","Brain RNA - cerebellum [nTPM]":"15.9","Brain RNA - cerebral cortex [nTPM]":"23.3","Brain RNA - hippocampal formation [nTPM]":"15.4","Brain RNA - hypothalamus [nTPM]":"19.6","Brain RNA - medulla oblongata [nTPM]":"23.4","Brain RNA - midbrain [nTPM]":"19.9","Brain RNA - pons [nTPM]":"18.4","Brain RNA - spinal cord [nTPM]":"18.1","Brain RNA - thalamus [nTPM]":"18.1","Brain RNA - white matter [nTPM]":"18.0","Single Cell Type RNA - Adipocytes [nTPM]":"45.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"90.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"76.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"183.0","Single Cell Type RNA - Club cells [nTPM]":"22.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"280.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"442.3","Single Cell Type RNA - Endothelial cells [nTPM]":"45.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"40.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.7","Single Cell Type RNA - Fibroblasts [nTPM]":"684.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.6","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"114.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1444.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"40.9","Single Cell Type RNA - Langerhans cells [nTPM]":"66.9","Single Cell Type RNA - Late spermatids [nTPM]":"29.2","Single Cell Type RNA - Leydig cells [nTPM]":"1142.6","Single Cell Type RNA - Macrophages [nTPM]":"7.0","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"388.1","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"170.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"87.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"140.4","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - T-cells [nTPM]":"11.5","Single Cell Type RNA - Theca cells [nTPM]":"15.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.2"},{"Gene":"C1S","Gene synonym":[],"Ensembl":"ENSG00000182326","Gene description":"Complement C1s","Uniprot":["P09871"],"Chromosome":"12","Position":"6988259-7071032","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant","Ehlers-Danlos syndrome","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"2915.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"687.0","Hepatocytes":"2795.1","Leydig cells":"1193.2","Peritubular cells":"640.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"276.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"2.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"granulocytes":"2.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"769.5","ASC TERT1":"1012.7","BJ hTERT+":"336.1","HSkMC":"540.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016722","HPA018852"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":93000000000,"Blood concentration - Conc. blood MS [pg\/L]":"14000000000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016722":null,"HPA018852":"AB_1847112"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.73e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.44e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"416.4","Tissue RNA - adrenal gland [nTPM]":"136.1","Tissue RNA - amygdala [nTPM]":"26.4","Tissue RNA - appendix [nTPM]":"207.7","Tissue RNA - basal ganglia [nTPM]":"28.5","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"252.5","Tissue RNA - cerebellum [nTPM]":"27.1","Tissue RNA - cerebral cortex [nTPM]":"43.1","Tissue RNA - cervix [nTPM]":"309.2","Tissue RNA - choroid plexus [nTPM]":"36.7","Tissue RNA - colon [nTPM]":"192.4","Tissue RNA - duodenum [nTPM]":"84.6","Tissue RNA - endometrium 1 [nTPM]":"209.0","Tissue RNA - epididymis [nTPM]":"147.2","Tissue RNA - esophagus [nTPM]":"152.9","Tissue RNA - fallopian tube [nTPM]":"315.4","Tissue RNA - gallbladder [nTPM]":"543.8","Tissue RNA - heart muscle [nTPM]":"191.5","Tissue RNA - hippocampal formation [nTPM]":"25.4","Tissue RNA - hypothalamus [nTPM]":"34.8","Tissue RNA - kidney [nTPM]":"60.2","Tissue RNA - liver [nTPM]":"2915.2","Tissue RNA - lung [nTPM]":"224.9","Tissue RNA - lymph node [nTPM]":"209.2","Tissue RNA - medulla oblongata [nTPM]":"44.3","Tissue RNA - midbrain [nTPM]":"31.7","Tissue RNA - ovary [nTPM]":"485.9","Tissue RNA - pancreas [nTPM]":"62.1","Tissue RNA - parathyroid gland [nTPM]":"21.8","Tissue RNA - pituitary gland [nTPM]":"33.1","Tissue RNA - placenta [nTPM]":"52.9","Tissue RNA - pons [nTPM]":"31.2","Tissue RNA - prostate [nTPM]":"174.4","Tissue RNA - rectum [nTPM]":"215.2","Tissue RNA - retina [nTPM]":"9.7","Tissue RNA - salivary gland [nTPM]":"96.9","Tissue RNA - seminal vesicle [nTPM]":"139.1","Tissue RNA - skeletal muscle [nTPM]":"57.0","Tissue RNA - skin 1 [nTPM]":"104.1","Tissue RNA - small intestine [nTPM]":"154.2","Tissue RNA - smooth muscle [nTPM]":"251.8","Tissue RNA - spinal cord [nTPM]":"30.9","Tissue RNA - spleen [nTPM]":"168.5","Tissue RNA - stomach 1 [nTPM]":"150.1","Tissue RNA - testis [nTPM]":"90.0","Tissue RNA - thalamus [nTPM]":"30.9","Tissue RNA - thymus [nTPM]":"88.1","Tissue RNA - thyroid gland [nTPM]":"139.0","Tissue RNA - tongue [nTPM]":"154.7","Tissue RNA - tonsil [nTPM]":"192.5","Tissue RNA - urinary bladder [nTPM]":"455.7","Tissue RNA - vagina [nTPM]":"189.8","Tissue RNA - white matter [nTPM]":"31.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"18.6","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"10.2","Cell RNA - ASC diff [nTPM]":"769.5","Cell RNA - ASC TERT1 [nTPM]":"1012.7","Cell RNA - BEWO [nTPM]":"4.5","Cell RNA - BJ [nTPM]":"143.3","Cell RNA - BJ hTERT+ [nTPM]":"336.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"135.7","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"19.7","Cell RNA - fHDF\/TERT166 [nTPM]":"179.6","Cell RNA - GAMG [nTPM]":"20.2","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"2.1","Cell RNA - HBF TERT88 [nTPM]":"6.7","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"5.6","Cell RNA - Hep G2 [nTPM]":"48.2","Cell RNA - HHSteC [nTPM]":"230.3","Cell RNA - HL-60 [nTPM]":"1.8","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"540.2","Cell RNA - hTCEpi [nTPM]":"2.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.2","Cell RNA - hTERT-HME1 [nTPM]":"4.4","Cell RNA - hTERT-RPE1 [nTPM]":"94.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"9.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"10.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"3.1","Cell RNA - RT4 [nTPM]":"2.5","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"86.6","Cell RNA - SK-BR-3 [nTPM]":"1.8","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"17.4","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"34.2","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"133.8","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"73.6","Cell RNA - U-937 [nTPM]":"1.2","Cell RNA - WM-115 [nTPM]":"2.5","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"26.4","Brain RNA - basal ganglia [nTPM]":"28.5","Brain RNA - cerebellum [nTPM]":"27.1","Brain RNA - cerebral cortex [nTPM]":"43.1","Brain RNA - hippocampal formation [nTPM]":"25.4","Brain RNA - hypothalamus [nTPM]":"34.8","Brain RNA - medulla oblongata [nTPM]":"44.3","Brain RNA - midbrain [nTPM]":"31.7","Brain RNA - pons [nTPM]":"31.2","Brain RNA - spinal cord [nTPM]":"30.9","Brain RNA - thalamus [nTPM]":"30.9","Brain RNA - white matter [nTPM]":"31.3","Single Cell Type RNA - Adipocytes [nTPM]":"37.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"41.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"76.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"171.6","Single Cell Type RNA - Club cells [nTPM]":"15.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"285.2","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"272.4","Single Cell Type RNA - Endothelial cells [nTPM]":"30.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"112.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"687.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.3","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"25.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"93.5","Single Cell Type RNA - Hepatocytes [nTPM]":"2795.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"62.8","Single Cell Type RNA - Langerhans cells [nTPM]":"103.7","Single Cell Type RNA - Late spermatids [nTPM]":"29.9","Single Cell Type RNA - Leydig cells [nTPM]":"1193.2","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"640.1","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"127.6","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"30.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"C2","Gene synonym":[],"Ensembl":"ENSG00000166278","Gene description":"Complement C2","Uniprot":["P06681"],"Chromosome":"6","Position":"31897785-31945672","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"477.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"142.4","Hepatocytes":"380.3","Hofbauer cells":"282.7","Kupffer cells":"99.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"100.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"21.1","non-classical monocyte":"25.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"monocytes":"25.9"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Karpas-707":"284.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016775"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016775":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.64e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"42.6","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"27.6","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"11.7","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"8.1","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"14.3","Tissue RNA - duodenum [nTPM]":"16.7","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"12.0","Tissue RNA - gallbladder [nTPM]":"23.0","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"477.9","Tissue RNA - lung [nTPM]":"80.0","Tissue RNA - lymph node [nTPM]":"27.8","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"48.4","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"13.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"30.2","Tissue RNA - smooth muscle [nTPM]":"23.6","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"46.3","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"5.5","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"12.5","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"6.8","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"52.8","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"284.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"16.5","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"31.6","Cell RNA - U-698 [nTPM]":"2.7","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"5.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"21.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"25.9","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"142.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"380.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"282.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"99.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"32.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"7.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"33.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"C3","Gene synonym":["ARMD9","C3a","C3b","CPAMD1"],"Ensembl":"ENSG00000125730","Gene description":"Complement C3","Uniprot":["P01024"],"Chromosome":"19","Position":"6677704-6730562","Protein class":["Candidate cardiovascular disease genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Complement pathway","Fatty acid metabolism","Immunity","Inflammatory response","Innate immunity","Lipid metabolism"],"Molecular function":null,"Disease involvement":["Age-related macular degeneration","Disease variant","FDA approved drug targets","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"liver":"4761.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hepatocytes":"4512.2"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"liver cancer":"1213.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"non-classical monocyte":"13.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"monocytes":"13.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"BJ hTERT+":"357.8","EFO-21":"738.6","Hep G2":"795.3","HSkMC":"534.8","SiHa":"209.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003563","CAB004209","HPA020432"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1260000000000,"Blood concentration - Conc. blood MS [pg\/L]":"200000000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004209":"AB_627277","HPA003563":"AB_1847117","HPA020432":"AB_1847118"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Tissue RNA - adipose tissue [nTPM]":"585.2","Tissue RNA - adrenal gland [nTPM]":"286.5","Tissue RNA - amygdala [nTPM]":"46.0","Tissue RNA - appendix [nTPM]":"194.3","Tissue RNA - basal ganglia [nTPM]":"53.7","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"213.9","Tissue RNA - cerebellum [nTPM]":"47.8","Tissue RNA - cerebral cortex [nTPM]":"46.0","Tissue RNA - cervix [nTPM]":"237.5","Tissue RNA - choroid plexus [nTPM]":"31.5","Tissue RNA - colon [nTPM]":"128.9","Tissue RNA - duodenum [nTPM]":"22.9","Tissue RNA - endometrium 1 [nTPM]":"82.9","Tissue RNA - epididymis [nTPM]":"41.1","Tissue RNA - esophagus [nTPM]":"76.4","Tissue RNA - fallopian tube [nTPM]":"350.3","Tissue RNA - gallbladder [nTPM]":"354.9","Tissue RNA - heart muscle [nTPM]":"221.6","Tissue RNA - hippocampal formation [nTPM]":"36.5","Tissue RNA - hypothalamus [nTPM]":"81.8","Tissue RNA - kidney [nTPM]":"51.4","Tissue RNA - liver [nTPM]":"4761.3","Tissue RNA - lung [nTPM]":"176.0","Tissue RNA - lymph node [nTPM]":"68.2","Tissue RNA - medulla oblongata [nTPM]":"143.3","Tissue RNA - midbrain [nTPM]":"99.2","Tissue RNA - ovary [nTPM]":"228.1","Tissue RNA - pancreas [nTPM]":"182.7","Tissue RNA - parathyroid gland [nTPM]":"17.9","Tissue RNA - pituitary gland [nTPM]":"21.8","Tissue RNA - placenta [nTPM]":"17.7","Tissue RNA - pons [nTPM]":"116.4","Tissue RNA - prostate [nTPM]":"35.4","Tissue RNA - rectum [nTPM]":"76.5","Tissue RNA - retina [nTPM]":"11.7","Tissue RNA - salivary gland [nTPM]":"155.6","Tissue RNA - seminal vesicle [nTPM]":"57.4","Tissue RNA - skeletal muscle [nTPM]":"36.6","Tissue RNA - skin 1 [nTPM]":"51.4","Tissue RNA - small intestine [nTPM]":"156.4","Tissue RNA - smooth muscle [nTPM]":"123.0","Tissue RNA - spinal cord [nTPM]":"89.9","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"107.9","Tissue RNA - testis [nTPM]":"41.1","Tissue RNA - thalamus [nTPM]":"103.4","Tissue RNA - thymus [nTPM]":"34.1","Tissue RNA - thyroid gland [nTPM]":"92.4","Tissue RNA - tongue [nTPM]":"52.0","Tissue RNA - tonsil [nTPM]":"126.4","Tissue RNA - urinary bladder [nTPM]":"363.3","Tissue RNA - vagina [nTPM]":"101.3","Tissue RNA - white matter [nTPM]":"121.9","Cell RNA - A-431 [nTPM]":"65.0","Cell RNA - A549 [nTPM]":"23.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"10.8","Cell RNA - ASC TERT1 [nTPM]":"36.0","Cell RNA - BEWO [nTPM]":"74.7","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"357.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"49.5","Cell RNA - Daudi [nTPM]":"1.9","Cell RNA - EFO-21 [nTPM]":"738.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"54.2","Cell RNA - HaCaT [nTPM]":"46.6","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"43.1","Cell RNA - HBF TERT88 [nTPM]":"6.9","Cell RNA - HDLM-2 [nTPM]":"24.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"3.1","Cell RNA - HeLa [nTPM]":"31.2","Cell RNA - Hep G2 [nTPM]":"795.3","Cell RNA - HHSteC [nTPM]":"16.3","Cell RNA - HL-60 [nTPM]":"6.2","Cell RNA - HMC-1 [nTPM]":"9.1","Cell RNA - HSkMC [nTPM]":"534.8","Cell RNA - hTCEpi [nTPM]":"12.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.8","Cell RNA - hTERT-HME1 [nTPM]":"27.3","Cell RNA - hTERT-RPE1 [nTPM]":"9.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"2.1","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"5.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"32.1","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"209.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"17.2","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"3.5","Cell RNA - U-138 MG [nTPM]":"5.7","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"4.8","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"75.1","Cell RNA - U-937 [nTPM]":"4.5","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"46.0","Brain RNA - basal ganglia [nTPM]":"53.7","Brain RNA - cerebellum [nTPM]":"47.8","Brain RNA - cerebral cortex [nTPM]":"46.0","Brain RNA - hippocampal formation [nTPM]":"36.5","Brain RNA - hypothalamus [nTPM]":"81.8","Brain RNA - medulla oblongata [nTPM]":"143.3","Brain RNA - midbrain [nTPM]":"99.2","Brain RNA - pons [nTPM]":"116.4","Brain RNA - spinal cord [nTPM]":"89.9","Brain RNA - thalamus [nTPM]":"103.4","Brain RNA - white matter [nTPM]":"121.9","Single Cell Type RNA - Adipocytes [nTPM]":"36.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"473.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"29.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"141.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"783.5","Single Cell Type RNA - Club cells [nTPM]":"422.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"494.1","Single Cell Type RNA - Early spermatids [nTPM]":"45.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.5","Single Cell Type RNA - Endothelial cells [nTPM]":"26.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"209.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"136.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"482.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"124.9","Single Cell Type RNA - Hepatocytes [nTPM]":"4512.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"164.5","Single Cell Type RNA - Langerhans cells [nTPM]":"44.8","Single Cell Type RNA - Late spermatids [nTPM]":"97.5","Single Cell Type RNA - Leydig cells [nTPM]":"226.2","Single Cell Type RNA - Macrophages [nTPM]":"45.1","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"70.3","Single Cell Type RNA - monocytes [nTPM]":"14.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"376.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"53.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"177.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.1","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.7","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"38.2"},{"Gene":"C4A","Gene synonym":["C4","C4A2","C4A3","C4A4","C4A6","C4B","C4S","CO4","CPAMD2","RG"],"Ensembl":"ENSG00000244731","Gene description":"Complement C4A (Rodgers blood group)","Uniprot":["P0C0L4"],"Chromosome":"6","Position":"31982057-32002681","Protein class":["Blood group antigen proteins","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Blood group antigen"],"Disease involvement":["Disease variant","FDA approved drug targets","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"115.8","liver":"336.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"9.6","Alveolar cells type 2":"46.4","Cardiomyocytes":"8.3","Club cells":"13.6","Fibroblasts":"19.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"27.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"58.5","HSkMC":"72.8","U-266\/70":"17.1","U-266\/84":"33.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009811","CAB032603","HPA046356","HPA048287","HPA050103"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":342000000,"Blood concentration - Conc. blood MS [pg\/L]":"120000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009811":"AB_2066891","CAB032603":"AB_2290613","HPA046356":"AB_2679635","HPA048287":"AB_2680341","HPA050103":"AB_2681016"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"115.8","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"10.6","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"31.3","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"16.9","Tissue RNA - epididymis [nTPM]":"11.8","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"29.9","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"21.8","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"43.1","Tissue RNA - liver [nTPM]":"336.8","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"57.5","Tissue RNA - pancreas [nTPM]":"23.0","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"20.6","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"3.7","Tissue RNA - retina [nTPM]":"5.5","Tissue RNA - salivary gland [nTPM]":"14.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"17.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"15.3","Tissue RNA - stomach 1 [nTPM]":"11.7","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"44.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"23.1","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"5.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"58.5","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"72.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"3.9","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"17.1","Cell RNA - U-266\/84 [nTPM]":"33.9","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"13.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"6.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"C4B","Gene synonym":["C4B1","C4B3","C4F","CH","CO4","CPAMD3"],"Ensembl":"ENSG00000224389","Gene description":"Complement C4B (Chido blood group)","Uniprot":["P0C0L5"],"Chromosome":"6","Position":"32014795-32035418","Protein class":["Blood group antigen proteins","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Blood group antigen"],"Disease involvement":["FDA approved drug targets","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"221.5","liver":"385.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"103.9","Cardiomyocytes":"71.8","Club cells":"22.9","Fibroblasts":"53.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"33.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Karpas-707":"129.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046356","HPA048287","HPA050103"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046356":"AB_2679635","HPA048287":"AB_2680341","HPA050103":"AB_2681016"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.7","Tissue RNA - adrenal gland [nTPM]":"221.5","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"15.9","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"27.3","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"16.6","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"24.0","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"22.7","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"13.3","Tissue RNA - kidney [nTPM]":"39.8","Tissue RNA - liver [nTPM]":"385.2","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"7.1","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"56.5","Tissue RNA - pancreas [nTPM]":"25.1","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"20.1","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"21.0","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"16.6","Tissue RNA - smooth muscle [nTPM]":"9.7","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"16.3","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"49.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"18.5","Tissue RNA - vagina [nTPM]":"3.7","Tissue RNA - white matter [nTPM]":"11.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"21.0","Cell RNA - HHSteC [nTPM]":"7.8","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"26.2","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"129.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"13.3","Brain RNA - medulla oblongata [nTPM]":"7.1","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"11.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"103.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"71.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"22.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"53.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"C4BPA","Gene synonym":["C4BP"],"Ensembl":"ENSG00000123838","Gene description":"Complement component 4 binding protein alpha","Uniprot":["P04003"],"Chromosome":"1","Position":"207104233-207144972","Protein class":["Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"1918.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Alveolar cells type 1":"493.6","Alveolar cells type 2":"660.8","Hepatocytes":"1020.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"434.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"137","RNA blood cell specific nTPM":{"neutrophil":"29.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"137","RNA blood lineage specific nTPM":{"granulocytes":"29.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Hep G2":"37.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000926","HPA001578"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":30800000000,"Blood concentration - Conc. blood MS [pg\/L]":"28000000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA000926":"AB_1078355","HPA001578":"AB_1078354"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.37e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"6.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.0","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"1918.6","Tissue RNA - lung [nTPM]":"173.3","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.7","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"37.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"7.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"29.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"493.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"660.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"22.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"21.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1020.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"39.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.6","Single Cell Type RNA - Paneth cells [nTPM]":"32.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"16.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"C4BPB","Gene synonym":["C4BP"],"Ensembl":"ENSG00000123843","Gene description":"Complement component 4 binding protein beta","Uniprot":["P20851"],"Chromosome":"1","Position":"207088860-207099993","Protein class":["Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"liver":"471.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hepatocytes":"597.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"19","RNA cancer specific FPKM":{"liver cancer":"83.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"16","RNA cell line specific nTPM":{"CACO-2":"116.4","HeLa":"46.2","Hep G2":"151.6","OE19":"57.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000925","HPA051620"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":265000000000,"Blood concentration - Conc. blood MS [pg\/L]":"1100000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA000925":null,"HPA051620":"AB_2681554"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"471.3","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"44.2","Tissue RNA - pancreas [nTPM]":"9.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"6.2","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"8.4","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"116.4","Cell RNA - CAPAN-2 [nTPM]":"5.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"46.2","Cell RNA - Hep G2 [nTPM]":"151.6","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"57.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"3.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"88.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"597.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"69.2","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"143.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"C5","Gene synonym":["C5a","C5b","CPAMD4"],"Ensembl":"ENSG00000106804","Gene description":"Complement C5","Uniprot":["P01031"],"Chromosome":"9","Position":"120952335-121050275","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Complement pathway","Cytolysis","Immunity","Inflammatory response","Innate immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"liver":"433.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Hepatocytes":"538.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"17","RNA cancer specific FPKM":{"liver cancer":"73.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"28.4","Hep G2":"30.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029339"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":113000000000,"Blood concentration - Conc. blood MS [pg\/L]":"39000000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA029339":"AB_10601125"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.9","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"1.1","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"2.8","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"2.7","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"3.0","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"433.7","Tissue RNA - lung [nTPM]":"7.0","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"3.3","Tissue RNA - pancreas [nTPM]":"14.9","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"2.8","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"2.1","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"28.4","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"11.3","Cell RNA - ASC diff [nTPM]":"8.0","Cell RNA - ASC TERT1 [nTPM]":"9.2","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"2.8","Cell RNA - Daudi [nTPM]":"4.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.8","Cell RNA - GAMG [nTPM]":"3.8","Cell RNA - HaCaT [nTPM]":"11.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"1.5","Cell RNA - Hep G2 [nTPM]":"30.4","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.0","Cell RNA - hTERT-HME1 [nTPM]":"3.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"1.0","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"3.8","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"5.6","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"7.0","Cell RNA - PC-3 [nTPM]":"10.9","Cell RNA - REH [nTPM]":"2.5","Cell RNA - RH-30 [nTPM]":"2.8","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"2.7","Cell RNA - SuSa [nTPM]":"4.4","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"3.4","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"1.7","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.8","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.6","Single Cell Type RNA - Astrocytes [nTPM]":"30.0","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"538.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"3.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"3.8","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"7.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"C6","Gene synonym":[],"Ensembl":"ENSG00000039537","Gene description":"Complement C6","Uniprot":["P13671"],"Chromosome":"5","Position":"41142116-41261438","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Complement pathway","Cytolysis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"12","RNA tissue specific nTPM":{"liver":"665.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"127.2","Hepatocytes":"376.9","Late spermatids":"54.8","Leydig cells":"120.2","Respiratory ciliated cells":"58.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"liver cancer":"49.0","pancreatic cancer":"12.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"ASC diff":"4.5","ASC TERT1":"6.2","HSkMC":"16.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043823","CAB069427"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":45000000000,"Blood concentration - Conc. blood MS [pg\/L]":"9200000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB069427":"AB_1614336","HPA043823":"AB_10960262"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.31e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"43.9","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"57.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"665.9","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"42.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.9","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"4.5","Cell RNA - ASC TERT1 [nTPM]":"6.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"127.2","Single Cell Type RNA - Club cells [nTPM]":"7.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"376.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"54.8","Single Cell Type RNA - Leydig cells [nTPM]":"120.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"C7","Gene synonym":[],"Ensembl":"ENSG00000112936","Gene description":"Complement C7","Uniprot":["P10643"],"Chromosome":"5","Position":"40909497-40984643","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Complement pathway","Cytolysis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"735.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Fibroblasts":"578.4","Hepatic stellate cells":"662.5","Leydig cells":"1058.5","Sertoli cells":"309.0","Theca cells":"503.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"pancreatic cancer":"73.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"ASC diff":"116.5","HHSteC":"155.1","HSkMC":"212.1","SH-SY5Y":"146.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"13.7"},"Antibody":["HPA001465"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001465":"AB_1078554"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.89e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"470.9","Tissue RNA - adrenal gland [nTPM]":"607.7","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"21.7","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"46.4","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"9.6","Tissue RNA - cervix [nTPM]":"118.5","Tissue RNA - choroid plexus [nTPM]":"13.6","Tissue RNA - colon [nTPM]":"165.3","Tissue RNA - duodenum [nTPM]":"19.3","Tissue RNA - endometrium 1 [nTPM]":"124.6","Tissue RNA - epididymis [nTPM]":"163.6","Tissue RNA - esophagus [nTPM]":"52.9","Tissue RNA - fallopian tube [nTPM]":"377.3","Tissue RNA - gallbladder [nTPM]":"211.7","Tissue RNA - heart muscle [nTPM]":"558.7","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"298.1","Tissue RNA - liver [nTPM]":"110.6","Tissue RNA - lung [nTPM]":"206.7","Tissue RNA - lymph node [nTPM]":"99.2","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"735.4","Tissue RNA - pancreas [nTPM]":"149.8","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"23.1","Tissue RNA - placenta [nTPM]":"359.2","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"101.6","Tissue RNA - rectum [nTPM]":"32.5","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"18.0","Tissue RNA - seminal vesicle [nTPM]":"105.7","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"12.6","Tissue RNA - small intestine [nTPM]":"139.8","Tissue RNA - smooth muscle [nTPM]":"256.3","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"138.2","Tissue RNA - stomach 1 [nTPM]":"120.2","Tissue RNA - testis [nTPM]":"28.0","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"32.2","Tissue RNA - thyroid gland [nTPM]":"105.1","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"22.5","Tissue RNA - urinary bladder [nTPM]":"122.1","Tissue RNA - vagina [nTPM]":"118.3","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"116.5","Cell RNA - ASC TERT1 [nTPM]":"16.8","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"155.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"212.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"146.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"9.6","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"7.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"56.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"127.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"54.8","Single Cell Type RNA - Erythroid cells [nTPM]":"26.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"578.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"662.5","Single Cell Type RNA - Hepatocytes [nTPM]":"8.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"29.8","Single Cell Type RNA - Leydig cells [nTPM]":"1058.5","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"3.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.9","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"309.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"503.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"C8A","Gene synonym":[],"Ensembl":"ENSG00000157131","Gene description":"Complement C8 alpha chain","Uniprot":["P07357"],"Chromosome":"1","Position":"56854797-56918223","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Complement alternate pathway","Complement pathway","Cytolysis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"195","RNA tissue specific nTPM":{"liver":"635.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"36","RNA single cell type specific nTPM":{"Hepatocytes":"296.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"279","RNA cancer specific FPKM":{"liver cancer":"85.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Hep G2":"1.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6400000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"635.7","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"296.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"C8B","Gene synonym":[],"Ensembl":"ENSG00000021852","Gene description":"Complement C8 beta chain","Uniprot":["P07358"],"Chromosome":"1","Position":"56929207-56966140","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Complement pathway","Cytolysis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"156","RNA tissue specific nTPM":{"liver":"840.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Hepatocytes":"295.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"181","RNA cancer specific FPKM":{"liver cancer":"107.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"22","RNA blood cell specific nTPM":{"basophil":"2.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"22","RNA blood lineage specific nTPM":{"granulocytes":"2.1"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Hep G2":"1.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023694"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6700000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA023694":"AB_1847128"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.31e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"840.0","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"295.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"C8G","Gene synonym":[],"Ensembl":"ENSG00000176919","Gene description":"Complement C8 gamma chain","Uniprot":["P07360"],"Chromosome":"9","Position":"136945185-136946975","Protein class":["Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Complement pathway","Cytolysis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"liver":"564.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hepatocytes":"1134.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"58","RNA cancer specific FPKM":{"liver cancer":"260.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"HMC-1":"41.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046269"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2800000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046269":"AB_2679606"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.99e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.2","Tissue RNA - duodenum [nTPM]":"31.2","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"564.4","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"17.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"41.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1134.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"25.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"122.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"C9","Gene synonym":[],"Ensembl":"ENSG00000113600","Gene description":"Complement C9","Uniprot":["P02748"],"Chromosome":"5","Position":"39284140-39424868","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Complement pathway","Cytolysis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Age-related macular degeneration","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"288","RNA tissue specific nTPM":{"liver":"1397.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"37","RNA single cell type specific nTPM":{"Hepatocytes":"1962.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"244","RNA cancer specific FPKM":{"liver cancer":"90.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"JURKAT":"9.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002151","HPA029577"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":69600000000,"Blood concentration - Conc. blood MS [pg\/L]":"64000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002151":"AB_563670","HPA029577":"AB_10603779"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"4.8","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"1397.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"9.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"2.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1962.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"52.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CARD11","Gene synonym":["BIMP3","CARMA1"],"Ensembl":"ENSG00000198286","Gene description":"Caspase recruitment domain family member 11","Uniprot":["Q9BXL7"],"Chromosome":"7","Position":"2906142-3043867","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"47.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"34.9","dendritic cells":"47.2","Microglial cells":"49.6","NK-cells":"28.8","Pancreatic endocrine cells":"24.9","Plasma cells":"26.7","T-cells":"28.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"31.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"31.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"122.7","K-562":"50.1","RT4":"91.4","U-698":"108.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052984"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052984":"AB_2682005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.68e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"21.8","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"18.5","Tissue RNA - breast [nTPM]":"1.2","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"47.3","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"18.3","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"31.5","Tissue RNA - stomach 1 [nTPM]":"7.5","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"14.0","Tissue RNA - thymus [nTPM]":"20.9","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"29.5","Tissue RNA - urinary bladder [nTPM]":"17.1","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"32.4","Cell RNA - CAPAN-2 [nTPM]":"35.5","Cell RNA - Daudi [nTPM]":"122.7","Cell RNA - EFO-21 [nTPM]":"29.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"27.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"42.1","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"3.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"23.1","Cell RNA - JURKAT [nTPM]":"13.3","Cell RNA - K-562 [nTPM]":"50.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"4.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"44.9","Cell RNA - OE19 [nTPM]":"20.6","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"5.9","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"30.7","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"91.4","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"17.7","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"2.5","Cell RNA - TIME [nTPM]":"15.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"11.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"12.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"108.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"7.7","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.2","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"6.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"5.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"31.4","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"14.0","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"34.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"47.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"28.6","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.1"},{"Gene":"CASP10","Gene synonym":["FLICE-2","MCH4"],"Ensembl":"ENSG00000003400","Gene description":"Caspase 10","Uniprot":["Q92851"],"Chromosome":"2","Position":"201182898-201229406","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"71.3","NK-cells":"44.3","Paneth cells":"44.5","Plasma cells":"49.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"25.3"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003780","HPA017059"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB003780":"AB_289592","HPA017059":"AB_1846040"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.54e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"19.5","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"13.2","Tissue RNA - duodenum [nTPM]":"21.8","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"8.8","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"8.1","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"11.5","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"9.6","Tissue RNA - pons [nTPM]":"5.8","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"13.4","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"5.4","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"4.9","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"18.4","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"22.6","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"3.5","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"7.5","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.8","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"9.8","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"7.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.5","Cell RNA - GAMG [nTPM]":"1.7","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"2.3","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"2.1","Cell RNA - HEK 293 [nTPM]":"4.8","Cell RNA - HEL [nTPM]":"12.2","Cell RNA - HeLa [nTPM]":"4.0","Cell RNA - Hep G2 [nTPM]":"15.1","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"8.3","Cell RNA - HMC-1 [nTPM]":"12.7","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.3","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"6.0","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"8.8","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"8.7","Cell RNA - RT4 [nTPM]":"6.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"4.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"3.4","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"18.7","Cell RNA - U-266\/84 [nTPM]":"12.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"4.5","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"5.9","Blood RNA - classical monocyte [nTPM]":"11.7","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"16.5","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"8.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.6","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"7.7","Blood RNA - naive CD4 T-cell [nTPM]":"7.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.4","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"6.6","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"5.8","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"20.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"15.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"9.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"20.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"71.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.4","Single Cell Type RNA - Endothelial cells [nTPM]":"29.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"26.6","Single Cell Type RNA - Langerhans cells [nTPM]":"17.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"16.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"22.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"44.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"49.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"4.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.4","Single Cell Type RNA - Urothelial cells [nTPM]":"10.3"},{"Gene":"CASP8","Gene synonym":["Casp-8","FLICE","MACH","MCH5"],"Ensembl":"ENSG00000064012","Gene description":"Caspase 8","Uniprot":["Q14790"],"Chromosome":"2","Position":"201233443-201287711","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"66.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"107.4","NK-cells":"132.8","Plasma cells":"73.4","T-cells":"86.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001302","CAB002047","HPA005688","HPA006191"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002047":"AB_563465","HPA001302":"AB_1846057","HPA005688":"AB_1846056","HPA006191":"AB_2667535"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.5","Tissue RNA - adrenal gland [nTPM]":"10.2","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"28.6","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"66.6","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"16.1","Tissue RNA - duodenum [nTPM]":"20.5","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"13.2","Tissue RNA - esophagus [nTPM]":"12.9","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"19.6","Tissue RNA - lymph node [nTPM]":"37.7","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"9.9","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"17.6","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"37.1","Tissue RNA - stomach 1 [nTPM]":"15.9","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"24.4","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"18.0","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"33.6","Cell RNA - A549 [nTPM]":"26.6","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"22.2","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"29.7","Cell RNA - BEWO [nTPM]":"12.0","Cell RNA - BJ [nTPM]":"13.8","Cell RNA - BJ hTERT+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.2","Cell RNA - CACO-2 [nTPM]":"36.1","Cell RNA - CAPAN-2 [nTPM]":"54.9","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"29.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"28.7","Cell RNA - HaCaT [nTPM]":"16.2","Cell RNA - HAP1 [nTPM]":"17.2","Cell RNA - HBEC3-KT [nTPM]":"16.1","Cell RNA - HBF TERT88 [nTPM]":"31.3","Cell RNA - HDLM-2 [nTPM]":"21.1","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"31.0","Cell RNA - HeLa [nTPM]":"21.9","Cell RNA - Hep G2 [nTPM]":"35.1","Cell RNA - HHSteC [nTPM]":"17.1","Cell RNA - HL-60 [nTPM]":"25.6","Cell RNA - HMC-1 [nTPM]":"33.8","Cell RNA - HSkMC [nTPM]":"25.9","Cell RNA - hTCEpi [nTPM]":"38.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.1","Cell RNA - hTERT-HME1 [nTPM]":"23.9","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.1","Cell RNA - JURKAT [nTPM]":"26.9","Cell RNA - K-562 [nTPM]":"28.6","Cell RNA - Karpas-707 [nTPM]":"69.1","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"32.1","Cell RNA - NB-4 [nTPM]":"25.9","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"17.5","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"24.7","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"55.4","Cell RNA - RPTEC TERT1 [nTPM]":"30.8","Cell RNA - RT4 [nTPM]":"35.3","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"18.0","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"19.1","Cell RNA - TIME [nTPM]":"19.6","Cell RNA - U-138 MG [nTPM]":"17.3","Cell RNA - U-2 OS [nTPM]":"18.0","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"10.9","Cell RNA - U-266\/70 [nTPM]":"63.1","Cell RNA - U-266\/84 [nTPM]":"30.2","Cell RNA - U-698 [nTPM]":"21.2","Cell RNA - U-87 MG [nTPM]":"25.3","Cell RNA - U-937 [nTPM]":"33.1","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"76.1","Blood RNA - classical monocyte [nTPM]":"39.5","Blood RNA - eosinophil [nTPM]":"77.1","Blood RNA - gdT-cell [nTPM]":"70.7","Blood RNA - intermediate monocyte [nTPM]":"51.2","Blood RNA - MAIT T-cell [nTPM]":"66.0","Blood RNA - memory B-cell [nTPM]":"40.9","Blood RNA - memory CD4 T-cell [nTPM]":"57.8","Blood RNA - memory CD8 T-cell [nTPM]":"75.9","Blood RNA - myeloid DC [nTPM]":"41.6","Blood RNA - naive B-cell [nTPM]":"24.0","Blood RNA - naive CD4 T-cell [nTPM]":"37.0","Blood RNA - naive CD8 T-cell [nTPM]":"47.2","Blood RNA - neutrophil [nTPM]":"153.6","Blood RNA - NK-cell [nTPM]":"70.6","Blood RNA - non-classical monocyte [nTPM]":"51.5","Blood RNA - plasmacytoid DC [nTPM]":"18.6","Blood RNA - T-reg [nTPM]":"75.0","Blood RNA - total PBMC [nTPM]":"40.6","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"50.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - dendritic cells [nTPM]":"107.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.2","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"11.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"25.3","Single Cell Type RNA - Langerhans cells [nTPM]":"15.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"25.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"35.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"132.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"73.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"86.9","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.7"},{"Gene":"CD19","Gene synonym":[],"Ensembl":"ENSG00000177455","Gene description":"CD19 molecule","Uniprot":["P15391"],"Chromosome":"16","Position":"28931965-28939342","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"intestine":"33.0","lymphoid tissue":"75.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"135.3","Early spermatids":"38.2","Plasma cells":"30.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"80","RNA blood cell specific nTPM":{"memory B-cell":"138.2","naive B-cell":"172.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"89","RNA blood lineage specific nTPM":{"B-cells":"172.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"143.3","REH":"77.1","U-698":"33.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016110"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016110":"AB_626952"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.41e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"28.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"72.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"33.0","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"72.7","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"5.7","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"75.3","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"143.3","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"77.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"33.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"138.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"172.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"135.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"38.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"30.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"7.4","Single Cell Type RNA - Spermatogonia [nTPM]":"4.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CD247","Gene synonym":["CD3H","CD3Q","CD3Z"],"Ensembl":"ENSG00000198821","Gene description":"CD247 molecule","Uniprot":["P20963"],"Chromosome":"1","Position":"167430640-167518610","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"bone marrow":"49.0","lymphoid tissue":"179.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"dendritic cells":"492.1","NK-cells":"727.1","T-cells":"247.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"gdT-cell":"376.4","MAIT T-cell":"208.9","memory CD4 T-cell":"190.0","memory CD8 T-cell":"219.7","naive CD4 T-cell":"237.8","naive CD8 T-cell":"195.1","NK-cell":"225.3","T-reg":"254.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"NK-cells":"225.3","T-cells":"376.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"25","RNA cell line specific nTPM":{"HDLM-2":"155.9","JURKAT":"113.1","MOLT-4":"167.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004651","HPA008750"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004651":"AB_425347","HPA008750":"AB_1857863"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.12e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"25.3","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"49.0","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"2.5","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"7.1","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"57.7","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"40.2","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"179.4","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"36.4","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"5.7","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"155.9","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"113.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"167.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"8.3","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"376.4","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"208.9","Blood RNA - memory B-cell [nTPM]":"9.3","Blood RNA - memory CD4 T-cell [nTPM]":"190.0","Blood RNA - memory CD8 T-cell [nTPM]":"219.7","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"237.8","Blood RNA - naive CD8 T-cell [nTPM]":"195.1","Blood RNA - neutrophil [nTPM]":"8.7","Blood RNA - NK-cell [nTPM]":"225.3","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"254.5","Blood RNA - total PBMC [nTPM]":"231.2","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"2.5","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"492.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"7.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"727.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"51.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"247.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CD3D","Gene synonym":["T3D"],"Ensembl":"ENSG00000167286","Gene description":"CD3d molecule","Uniprot":["P04234"],"Chromosome":"11","Position":"118339075-118342705","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"lymphoid tissue":"906.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"dendritic cells":"231.0","T-cells":"665.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"52","RNA blood cell specific nTPM":{"gdT-cell":"1462.4","MAIT T-cell":"990.0","memory CD4 T-cell":"1206.1","memory CD8 T-cell":"1368.7","naive CD4 T-cell":"1091.4","naive CD8 T-cell":"1338.9","T-reg":"1660.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"66","RNA blood lineage specific nTPM":{"T-cells":"1660.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"JURKAT":"621.5","MOLT-4":"1299.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013055","HPA071778"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB013055":null,"HPA071778":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.46e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.70e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.16e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"77.5","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"28.6","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"21.7","Tissue RNA - endometrium 1 [nTPM]":"3.6","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"2.3","Tissue RNA - liver [nTPM]":"7.9","Tissue RNA - lung [nTPM]":"20.6","Tissue RNA - lymph node [nTPM]":"222.7","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"5.9","Tissue RNA - rectum [nTPM]":"22.4","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"4.0","Tissue RNA - small intestine [nTPM]":"30.1","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"60.9","Tissue RNA - stomach 1 [nTPM]":"23.8","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"906.7","Tissue RNA - thyroid gland [nTPM]":"3.8","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"166.9","Tissue RNA - urinary bladder [nTPM]":"26.7","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"621.5","Cell RNA - K-562 [nTPM]":"49.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1299.8","Cell RNA - NB-4 [nTPM]":"237.2","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"1.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"10.1","Blood RNA - classical monocyte [nTPM]":"5.3","Blood RNA - eosinophil [nTPM]":"4.6","Blood RNA - gdT-cell [nTPM]":"1462.4","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"990.0","Blood RNA - memory B-cell [nTPM]":"9.6","Blood RNA - memory CD4 T-cell [nTPM]":"1206.1","Blood RNA - memory CD8 T-cell [nTPM]":"1368.7","Blood RNA - myeloid DC [nTPM]":"5.0","Blood RNA - naive B-cell [nTPM]":"3.7","Blood RNA - naive CD4 T-cell [nTPM]":"1091.4","Blood RNA - naive CD8 T-cell [nTPM]":"1338.9","Blood RNA - neutrophil [nTPM]":"25.1","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"5.3","Blood RNA - plasmacytoid DC [nTPM]":"6.0","Blood RNA - T-reg [nTPM]":"1660.4","Blood RNA - total PBMC [nTPM]":"1138.7","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"2.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"231.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.9","Single Cell Type RNA - Langerhans cells [nTPM]":"28.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"25.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"665.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CD3E","Gene synonym":[],"Ensembl":"ENSG00000198851","Gene description":"CD3e molecule","Uniprot":["P07766"],"Chromosome":"11","Position":"118304730-118316175","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"lymphoid tissue":"640.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"dendritic cells":"213.6","NK-cells":"154.5","T-cells":"601.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"26","RNA blood cell specific nTPM":{"gdT-cell":"490.6","MAIT T-cell":"420.8","memory CD4 T-cell":"414.4","memory CD8 T-cell":"463.5","naive CD4 T-cell":"491.7","naive CD8 T-cell":"501.3","NK-cell":"202.2","T-reg":"426.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"NK-cells":"202.2","T-cells":"501.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"67","RNA cell line specific nTPM":{"JURKAT":"544.9","MOLT-4":"764.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000010","HPA040957","HPA043955","CAB072863","CAB072864"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 58: T-cells - T-cell receptor","Subcellular main location":["Endoplasmic reticulum","Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000010":"AB_2631163","CAB072863":"AB_2665707","CAB072864":"AB_2665708","HPA040957":"AB_2677222","HPA043955":"AB_2678747"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.72e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.30e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"5.6","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"85.8","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"36.7","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"15.3","Tissue RNA - duodenum [nTPM]":"22.0","Tissue RNA - endometrium 1 [nTPM]":"5.8","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"20.1","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"9.7","Tissue RNA - lung [nTPM]":"23.0","Tissue RNA - lymph node [nTPM]":"209.6","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"11.6","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"1.9","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"36.4","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"78.9","Tissue RNA - stomach 1 [nTPM]":"24.4","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"1.3","Tissue RNA - thymus [nTPM]":"640.4","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"1.6","Tissue RNA - tonsil [nTPM]":"147.0","Tissue RNA - urinary bladder [nTPM]":"24.8","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"544.9","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"2.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"764.9","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.6","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"9.8","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"16.4","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"490.6","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"420.8","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"414.4","Blood RNA - memory CD8 T-cell [nTPM]":"463.5","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"491.7","Blood RNA - naive CD8 T-cell [nTPM]":"501.3","Blood RNA - neutrophil [nTPM]":"12.2","Blood RNA - NK-cell [nTPM]":"202.2","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"8.6","Blood RNA - T-reg [nTPM]":"426.3","Blood RNA - total PBMC [nTPM]":"333.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.3","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"213.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.6","Single Cell Type RNA - Langerhans cells [nTPM]":"8.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"12.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"154.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"41.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"601.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CD3G","Gene synonym":[],"Ensembl":"ENSG00000160654","Gene description":"CD3g molecule","Uniprot":["P09693"],"Chromosome":"11","Position":"118344344-118355161","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"lymphoid tissue":"94.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"dendritic cells":"139.6","T-cells":"294.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"21","RNA blood cell specific nTPM":{"gdT-cell":"229.0","MAIT T-cell":"135.6","memory CD4 T-cell":"187.3","memory CD8 T-cell":"197.3","naive CD4 T-cell":"192.6","naive CD8 T-cell":"241.7","T-reg":"200.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"T-cells":"241.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"52","RNA cell line specific nTPM":{"JURKAT":"70.9","MOLT-4":"193.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017520","HPA038494"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB017520":"AB_831094","HPA038494":"AB_2676044"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.33e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.61e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.00e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"10.5","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"27.9","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"10.5","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"94.7","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"20.4","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"70.9","Cell RNA - K-562 [nTPM]":"2.5","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"193.8","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"9.2","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"229.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"135.6","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"187.3","Blood RNA - memory CD8 T-cell [nTPM]":"197.3","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"192.6","Blood RNA - naive CD8 T-cell [nTPM]":"241.7","Blood RNA - neutrophil [nTPM]":"6.4","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"200.0","Blood RNA - total PBMC [nTPM]":"90.4","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"7.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"139.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"8.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"294.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CD40","Gene synonym":["Bp50","p50","TNFRSF5"],"Ensembl":"ENSG00000101017","Gene description":"CD40 molecule","Uniprot":["P25942"],"Chromosome":"20","Position":"46118278-46129863","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"127.5","Basal respiratory cells":"126.0","Langerhans cells":"191.4","monocytes":"242.0","Prostatic glandular cells":"130.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"139.4","naive B-cell":"157.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"157.9","monocytes":"43.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"76.0","Daudi":"42.1","EFO-21":"131.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002495","HPA031567","HPA031568","CAB072868"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":705000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002495":"AB_563562","CAB072868":"AB_2665719","HPA031567":"AB_2673936","HPA031568":"AB_2673937"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"25.9","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"34.9","Tissue RNA - basal ganglia [nTPM]":"7.0","Tissue RNA - bone marrow [nTPM]":"2.7","Tissue RNA - breast [nTPM]":"20.5","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"11.8","Tissue RNA - duodenum [nTPM]":"12.6","Tissue RNA - endometrium 1 [nTPM]":"14.4","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"19.7","Tissue RNA - gallbladder [nTPM]":"14.3","Tissue RNA - heart muscle [nTPM]":"16.3","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"26.1","Tissue RNA - liver [nTPM]":"18.3","Tissue RNA - lung [nTPM]":"34.4","Tissue RNA - lymph node [nTPM]":"57.8","Tissue RNA - medulla oblongata [nTPM]":"8.0","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"24.5","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"46.5","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"23.6","Tissue RNA - rectum [nTPM]":"9.6","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"24.5","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"17.0","Tissue RNA - small intestine [nTPM]":"21.8","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"7.8","Tissue RNA - spleen [nTPM]":"35.1","Tissue RNA - stomach 1 [nTPM]":"15.6","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"20.4","Tissue RNA - tongue [nTPM]":"7.1","Tissue RNA - tonsil [nTPM]":"57.7","Tissue RNA - urinary bladder [nTPM]":"32.9","Tissue RNA - vagina [nTPM]":"21.0","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"26.6","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"12.8","Cell RNA - ASC diff [nTPM]":"4.7","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"5.0","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.6","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"76.0","Cell RNA - Daudi [nTPM]":"42.1","Cell RNA - EFO-21 [nTPM]":"131.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"18.7","Cell RNA - HaCaT [nTPM]":"3.1","Cell RNA - HAP1 [nTPM]":"2.3","Cell RNA - HBEC3-KT [nTPM]":"16.2","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"29.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"7.5","Cell RNA - HHSteC [nTPM]":"36.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"13.0","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"6.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"28.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"9.3","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"4.5","Cell RNA - RPTEC TERT1 [nTPM]":"32.7","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"2.7","Cell RNA - THP-1 [nTPM]":"14.5","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"41.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"29.2","Cell RNA - U-87 MG [nTPM]":"9.6","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"28.0","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"43.3","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"139.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"16.1","Blood RNA - naive B-cell [nTPM]":"157.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.7","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"32.1","Blood RNA - plasmacytoid DC [nTPM]":"8.3","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"20.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.0","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"8.0","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"7.8","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"68.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.0","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"127.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"63.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"126.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"32.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"68.4","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"61.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"37.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.3","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.3","Single Cell Type RNA - Hepatocytes [nTPM]":"17.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"40.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"191.4","Single Cell Type RNA - Late spermatids [nTPM]":"14.6","Single Cell Type RNA - Leydig cells [nTPM]":"25.7","Single Cell Type RNA - Macrophages [nTPM]":"48.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"242.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.9","Single Cell Type RNA - Paneth cells [nTPM]":"8.8","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"25.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"130.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"2.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.8","Single Cell Type RNA - Urothelial cells [nTPM]":"64.4"},{"Gene":"CD40LG","Gene synonym":["CD154","CD40L","gp39","hCD40L","HIGM1","IMD3","TNFSF5","TRAP"],"Ensembl":"ENSG00000102245","Gene description":"CD40 ligand","Uniprot":["P29965"],"Chromosome":"X","Position":"136648158-136660390","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"15.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"T-cells":"76.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"26.3","MAIT T-cell":"64.1","memory CD4 T-cell":"80.5","naive CD4 T-cell":"76.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"T-cells":"80.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"MOLT-4":"23.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045827","HPA072480"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":776000,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA045827":"AB_10959606","HPA072480":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.56e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"7.9","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.9","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"15.5","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"15.5","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"14.8","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"23.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"26.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"64.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"80.5","Blood RNA - memory CD8 T-cell [nTPM]":"11.7","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"76.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"10.5","Blood RNA - total PBMC [nTPM]":"13.6","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"76.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CD55","Gene synonym":["CR","CROM","DAF","TC"],"Ensembl":"ENSG00000196352","Gene description":"CD55 molecule (Cromer blood group)","Uniprot":["P08174"],"Chromosome":"1","Position":"207321532-207386804","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Blood group antigen","Host cell receptor for virus entry","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"2227.6","Syncytiotrophoblasts":"847.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"662.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HeLa":"472.3","HMC-1":"665.7","PC-3":"395.0","U-2197":"405.3"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002190","CAB010454","HPA024386"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":32300000,"Blood concentration - Conc. blood MS [pg\/L]":"360000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010454":"AB_2075970","HPA002190":"AB_1078472","HPA024386":"AB_1846319"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"64.9","Tissue RNA - adrenal gland [nTPM]":"161.5","Tissue RNA - amygdala [nTPM]":"13.8","Tissue RNA - appendix [nTPM]":"99.6","Tissue RNA - basal ganglia [nTPM]":"23.3","Tissue RNA - bone marrow [nTPM]":"134.0","Tissue RNA - breast [nTPM]":"59.0","Tissue RNA - cerebellum [nTPM]":"15.8","Tissue RNA - cerebral cortex [nTPM]":"28.3","Tissue RNA - cervix [nTPM]":"103.3","Tissue RNA - choroid plexus [nTPM]":"19.0","Tissue RNA - colon [nTPM]":"47.7","Tissue RNA - duodenum [nTPM]":"47.7","Tissue RNA - endometrium 1 [nTPM]":"58.3","Tissue RNA - epididymis [nTPM]":"17.3","Tissue RNA - esophagus [nTPM]":"58.3","Tissue RNA - fallopian tube [nTPM]":"28.0","Tissue RNA - gallbladder [nTPM]":"49.4","Tissue RNA - heart muscle [nTPM]":"48.4","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"29.4","Tissue RNA - kidney [nTPM]":"20.5","Tissue RNA - liver [nTPM]":"28.0","Tissue RNA - lung [nTPM]":"224.1","Tissue RNA - lymph node [nTPM]":"26.7","Tissue RNA - medulla oblongata [nTPM]":"21.1","Tissue RNA - midbrain [nTPM]":"20.0","Tissue RNA - ovary [nTPM]":"67.7","Tissue RNA - pancreas [nTPM]":"24.5","Tissue RNA - parathyroid gland [nTPM]":"28.9","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"92.5","Tissue RNA - pons [nTPM]":"26.2","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"42.9","Tissue RNA - retina [nTPM]":"9.2","Tissue RNA - salivary gland [nTPM]":"126.1","Tissue RNA - seminal vesicle [nTPM]":"18.1","Tissue RNA - skeletal muscle [nTPM]":"108.9","Tissue RNA - skin 1 [nTPM]":"85.9","Tissue RNA - small intestine [nTPM]":"50.7","Tissue RNA - smooth muscle [nTPM]":"46.6","Tissue RNA - spinal cord [nTPM]":"15.2","Tissue RNA - spleen [nTPM]":"43.1","Tissue RNA - stomach 1 [nTPM]":"44.0","Tissue RNA - testis [nTPM]":"36.0","Tissue RNA - thalamus [nTPM]":"20.8","Tissue RNA - thymus [nTPM]":"15.8","Tissue RNA - thyroid gland [nTPM]":"47.6","Tissue RNA - tongue [nTPM]":"59.5","Tissue RNA - tonsil [nTPM]":"41.3","Tissue RNA - urinary bladder [nTPM]":"183.2","Tissue RNA - vagina [nTPM]":"41.8","Tissue RNA - white matter [nTPM]":"34.4","Cell RNA - A-431 [nTPM]":"33.2","Cell RNA - A549 [nTPM]":"43.6","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"14.6","Cell RNA - ASC diff [nTPM]":"54.2","Cell RNA - ASC TERT1 [nTPM]":"55.1","Cell RNA - BEWO [nTPM]":"220.7","Cell RNA - BJ [nTPM]":"62.5","Cell RNA - BJ hTERT+ [nTPM]":"100.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.1","Cell RNA - CACO-2 [nTPM]":"139.5","Cell RNA - CAPAN-2 [nTPM]":"44.3","Cell RNA - Daudi [nTPM]":"60.8","Cell RNA - EFO-21 [nTPM]":"50.3","Cell RNA - fHDF\/TERT166 [nTPM]":"35.8","Cell RNA - GAMG [nTPM]":"123.3","Cell RNA - HaCaT [nTPM]":"17.4","Cell RNA - HAP1 [nTPM]":"65.2","Cell RNA - HBEC3-KT [nTPM]":"12.9","Cell RNA - HBF TERT88 [nTPM]":"29.1","Cell RNA - HDLM-2 [nTPM]":"29.0","Cell RNA - HEK 293 [nTPM]":"26.4","Cell RNA - HEL [nTPM]":"79.9","Cell RNA - HeLa [nTPM]":"472.3","Cell RNA - Hep G2 [nTPM]":"23.3","Cell RNA - HHSteC [nTPM]":"162.3","Cell RNA - HL-60 [nTPM]":"50.5","Cell RNA - HMC-1 [nTPM]":"665.7","Cell RNA - HSkMC [nTPM]":"25.9","Cell RNA - hTCEpi [nTPM]":"150.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.8","Cell RNA - hTERT-HME1 [nTPM]":"171.8","Cell RNA - hTERT-RPE1 [nTPM]":"133.8","Cell RNA - HUVEC TERT2 [nTPM]":"169.7","Cell RNA - JURKAT [nTPM]":"9.6","Cell RNA - K-562 [nTPM]":"89.6","Cell RNA - Karpas-707 [nTPM]":"29.3","Cell RNA - LHCN-M2 [nTPM]":"19.4","Cell RNA - MCF7 [nTPM]":"35.6","Cell RNA - MOLT-4 [nTPM]":"5.3","Cell RNA - NB-4 [nTPM]":"37.8","Cell RNA - NTERA-2 [nTPM]":"43.2","Cell RNA - OE19 [nTPM]":"78.9","Cell RNA - PC-3 [nTPM]":"395.0","Cell RNA - REH [nTPM]":"7.4","Cell RNA - RH-30 [nTPM]":"42.3","Cell RNA - RPMI-8226 [nTPM]":"50.7","Cell RNA - RPTEC TERT1 [nTPM]":"54.3","Cell RNA - RT4 [nTPM]":"30.7","Cell RNA - SCLC-21H [nTPM]":"17.7","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"321.2","Cell RNA - SK-BR-3 [nTPM]":"64.3","Cell RNA - SK-MEL-30 [nTPM]":"53.9","Cell RNA - SuSa [nTPM]":"95.1","Cell RNA - T-47d [nTPM]":"54.4","Cell RNA - THP-1 [nTPM]":"41.5","Cell RNA - TIME [nTPM]":"80.4","Cell RNA - U-138 MG [nTPM]":"17.6","Cell RNA - U-2 OS [nTPM]":"33.2","Cell RNA - U-2197 [nTPM]":"405.3","Cell RNA - U-251 MG [nTPM]":"23.8","Cell RNA - U-266\/70 [nTPM]":"24.7","Cell RNA - U-266\/84 [nTPM]":"31.4","Cell RNA - U-698 [nTPM]":"42.7","Cell RNA - U-87 MG [nTPM]":"44.8","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"78.9","Blood RNA - basophil [nTPM]":"317.7","Blood RNA - classical monocyte [nTPM]":"181.2","Blood RNA - eosinophil [nTPM]":"247.6","Blood RNA - gdT-cell [nTPM]":"35.0","Blood RNA - intermediate monocyte [nTPM]":"174.4","Blood RNA - MAIT T-cell [nTPM]":"51.8","Blood RNA - memory B-cell [nTPM]":"108.2","Blood RNA - memory CD4 T-cell [nTPM]":"46.0","Blood RNA - memory CD8 T-cell [nTPM]":"36.4","Blood RNA - myeloid DC [nTPM]":"121.7","Blood RNA - naive B-cell [nTPM]":"115.2","Blood RNA - naive CD4 T-cell [nTPM]":"102.6","Blood RNA - naive CD8 T-cell [nTPM]":"101.9","Blood RNA - neutrophil [nTPM]":"662.2","Blood RNA - NK-cell [nTPM]":"134.5","Blood RNA - non-classical monocyte [nTPM]":"223.7","Blood RNA - plasmacytoid DC [nTPM]":"64.8","Blood RNA - T-reg [nTPM]":"34.6","Blood RNA - total PBMC [nTPM]":"159.3","Brain RNA - amygdala [nTPM]":"13.8","Brain RNA - basal ganglia [nTPM]":"23.3","Brain RNA - cerebellum [nTPM]":"15.8","Brain RNA - cerebral cortex [nTPM]":"28.3","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"29.4","Brain RNA - medulla oblongata [nTPM]":"21.1","Brain RNA - midbrain [nTPM]":"20.0","Brain RNA - pons [nTPM]":"26.2","Brain RNA - spinal cord [nTPM]":"15.2","Brain RNA - thalamus [nTPM]":"20.8","Brain RNA - white matter [nTPM]":"34.4","Single Cell Type RNA - Adipocytes [nTPM]":"95.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"2227.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"405.3","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"529.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"705.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"214.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"143.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"59.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"72.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"542.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"217.5","Single Cell Type RNA - dendritic cells [nTPM]":"201.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"196.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"98.6","Single Cell Type RNA - Early spermatids [nTPM]":"324.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"345.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.9","Single Cell Type RNA - Endothelial cells [nTPM]":"143.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.3","Single Cell Type RNA - Erythroid cells [nTPM]":"79.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"180.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"411.7","Single Cell Type RNA - Fibroblasts [nTPM]":"244.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"387.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"709.3","Single Cell Type RNA - granulocytes [nTPM]":"146.9","Single Cell Type RNA - Granulosa cells [nTPM]":"88.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.8","Single Cell Type RNA - Hepatocytes [nTPM]":"9.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"70.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"155.7","Single Cell Type RNA - Ionocytes [nTPM]":"77.3","Single Cell Type RNA - Kupffer cells [nTPM]":"177.5","Single Cell Type RNA - Langerhans cells [nTPM]":"449.2","Single Cell Type RNA - Late spermatids [nTPM]":"66.3","Single Cell Type RNA - Leydig cells [nTPM]":"32.6","Single Cell Type RNA - Macrophages [nTPM]":"377.3","Single Cell Type RNA - Melanocytes [nTPM]":"160.1","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"122.6","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"69.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"388.9","Single Cell Type RNA - Paneth cells [nTPM]":"241.2","Single Cell Type RNA - Peritubular cells [nTPM]":"9.1","Single Cell Type RNA - Plasma cells [nTPM]":"305.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"334.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"138.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"259.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"98.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.9","Single Cell Type RNA - Spermatogonia [nTPM]":"13.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"273.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"765.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"847.7","Single Cell Type RNA - T-cells [nTPM]":"215.4","Single Cell Type RNA - Theca cells [nTPM]":"281.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"145.1","Single Cell Type RNA - Urothelial cells [nTPM]":"578.6"},{"Gene":"CD59","Gene synonym":["16.3A5","EJ16","EJ30","EL32","G344","MIC11","MIN1","MIN2","MIN3","MSK21","p18-20"],"Ensembl":"ENSG00000085063","Gene description":"CD59 molecule (CD59 blood group)","Uniprot":["P13987"],"Chromosome":"11","Position":"33703010-33736479","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"1445.2","Prostatic glandular cells":"1678.0","Urothelial cells":"1531.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"TIME":"3747.5","U-2197":"3049.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001448","HPA026494"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB001448":"AB_563604","HPA026494":"AB_1846321"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.81e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.10e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.92e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.39e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.03e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"517.4","Tissue RNA - adrenal gland [nTPM]":"248.3","Tissue RNA - amygdala [nTPM]":"284.5","Tissue RNA - appendix [nTPM]":"209.6","Tissue RNA - basal ganglia [nTPM]":"310.8","Tissue RNA - bone marrow [nTPM]":"198.8","Tissue RNA - breast [nTPM]":"555.9","Tissue RNA - cerebellum [nTPM]":"329.0","Tissue RNA - cerebral cortex [nTPM]":"365.1","Tissue RNA - cervix [nTPM]":"305.5","Tissue RNA - choroid plexus [nTPM]":"542.2","Tissue RNA - colon [nTPM]":"255.1","Tissue RNA - duodenum [nTPM]":"120.7","Tissue RNA - endometrium 1 [nTPM]":"290.7","Tissue RNA - epididymis [nTPM]":"971.7","Tissue RNA - esophagus [nTPM]":"478.9","Tissue RNA - fallopian tube [nTPM]":"368.1","Tissue RNA - gallbladder [nTPM]":"475.3","Tissue RNA - heart muscle [nTPM]":"608.3","Tissue RNA - hippocampal formation [nTPM]":"288.2","Tissue RNA - hypothalamus [nTPM]":"359.7","Tissue RNA - kidney [nTPM]":"577.4","Tissue RNA - liver [nTPM]":"339.8","Tissue RNA - lung [nTPM]":"553.5","Tissue RNA - lymph node [nTPM]":"148.8","Tissue RNA - medulla oblongata [nTPM]":"327.9","Tissue RNA - midbrain [nTPM]":"340.2","Tissue RNA - ovary [nTPM]":"228.5","Tissue RNA - pancreas [nTPM]":"353.6","Tissue RNA - parathyroid gland [nTPM]":"706.1","Tissue RNA - pituitary gland [nTPM]":"250.3","Tissue RNA - placenta [nTPM]":"485.6","Tissue RNA - pons [nTPM]":"340.9","Tissue RNA - prostate [nTPM]":"256.8","Tissue RNA - rectum [nTPM]":"271.4","Tissue RNA - retina [nTPM]":"130.7","Tissue RNA - salivary gland [nTPM]":"693.6","Tissue RNA - seminal vesicle [nTPM]":"443.2","Tissue RNA - skeletal muscle [nTPM]":"529.3","Tissue RNA - skin 1 [nTPM]":"282.8","Tissue RNA - small intestine [nTPM]":"167.9","Tissue RNA - smooth muscle [nTPM]":"380.0","Tissue RNA - spinal cord [nTPM]":"330.5","Tissue RNA - spleen [nTPM]":"131.8","Tissue RNA - stomach 1 [nTPM]":"422.7","Tissue RNA - testis [nTPM]":"127.7","Tissue RNA - thalamus [nTPM]":"337.0","Tissue RNA - thymus [nTPM]":"167.7","Tissue RNA - thyroid gland [nTPM]":"308.1","Tissue RNA - tongue [nTPM]":"915.0","Tissue RNA - tonsil [nTPM]":"288.6","Tissue RNA - urinary bladder [nTPM]":"550.5","Tissue RNA - vagina [nTPM]":"325.5","Tissue RNA - white matter [nTPM]":"315.6","Cell RNA - A-431 [nTPM]":"297.2","Cell RNA - A549 [nTPM]":"278.4","Cell RNA - AF22 [nTPM]":"77.6","Cell RNA - AN3-CA [nTPM]":"212.0","Cell RNA - ASC diff [nTPM]":"1697.1","Cell RNA - ASC TERT1 [nTPM]":"1314.9","Cell RNA - BEWO [nTPM]":"46.8","Cell RNA - BJ [nTPM]":"1765.7","Cell RNA - BJ hTERT+ [nTPM]":"1778.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"408.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"451.9","Cell RNA - CACO-2 [nTPM]":"129.7","Cell RNA - CAPAN-2 [nTPM]":"822.1","Cell RNA - Daudi [nTPM]":"23.9","Cell RNA - EFO-21 [nTPM]":"291.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1802.5","Cell RNA - GAMG [nTPM]":"475.5","Cell RNA - HaCaT [nTPM]":"314.0","Cell RNA - HAP1 [nTPM]":"141.0","Cell RNA - HBEC3-KT [nTPM]":"1589.9","Cell RNA - HBF TERT88 [nTPM]":"561.1","Cell RNA - HDLM-2 [nTPM]":"475.5","Cell RNA - HEK 293 [nTPM]":"218.2","Cell RNA - HEL [nTPM]":"31.3","Cell RNA - HeLa [nTPM]":"846.7","Cell RNA - Hep G2 [nTPM]":"193.1","Cell RNA - HHSteC [nTPM]":"483.2","Cell RNA - HL-60 [nTPM]":"183.4","Cell RNA - HMC-1 [nTPM]":"94.8","Cell RNA - HSkMC [nTPM]":"631.8","Cell RNA - hTCEpi [nTPM]":"387.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"343.3","Cell RNA - hTERT-HME1 [nTPM]":"1550.6","Cell RNA - hTERT-RPE1 [nTPM]":"1104.9","Cell RNA - HUVEC TERT2 [nTPM]":"2475.5","Cell RNA - JURKAT [nTPM]":"109.3","Cell RNA - K-562 [nTPM]":"207.9","Cell RNA - Karpas-707 [nTPM]":"585.9","Cell RNA - LHCN-M2 [nTPM]":"2575.4","Cell RNA - MCF7 [nTPM]":"282.7","Cell RNA - MOLT-4 [nTPM]":"79.9","Cell RNA - NB-4 [nTPM]":"70.3","Cell RNA - NTERA-2 [nTPM]":"43.5","Cell RNA - OE19 [nTPM]":"541.8","Cell RNA - PC-3 [nTPM]":"1421.8","Cell RNA - REH [nTPM]":"30.1","Cell RNA - RH-30 [nTPM]":"232.1","Cell RNA - RPMI-8226 [nTPM]":"227.8","Cell RNA - RPTEC TERT1 [nTPM]":"1304.4","Cell RNA - RT4 [nTPM]":"510.0","Cell RNA - SCLC-21H [nTPM]":"54.3","Cell RNA - SH-SY5Y [nTPM]":"79.5","Cell RNA - SiHa [nTPM]":"576.2","Cell RNA - SK-BR-3 [nTPM]":"243.7","Cell RNA - SK-MEL-30 [nTPM]":"298.2","Cell RNA - SuSa [nTPM]":"218.0","Cell RNA - T-47d [nTPM]":"187.5","Cell RNA - THP-1 [nTPM]":"18.1","Cell RNA - TIME [nTPM]":"3747.5","Cell RNA - U-138 MG [nTPM]":"838.6","Cell RNA - U-2 OS [nTPM]":"235.5","Cell RNA - U-2197 [nTPM]":"3049.9","Cell RNA - U-251 MG [nTPM]":"595.9","Cell RNA - U-266\/70 [nTPM]":"273.8","Cell RNA - U-266\/84 [nTPM]":"558.8","Cell RNA - U-698 [nTPM]":"30.4","Cell RNA - U-87 MG [nTPM]":"734.2","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"1556.9","Blood RNA - basophil [nTPM]":"164.9","Blood RNA - classical monocyte [nTPM]":"22.3","Blood RNA - eosinophil [nTPM]":"209.6","Blood RNA - gdT-cell [nTPM]":"50.9","Blood RNA - intermediate monocyte [nTPM]":"7.9","Blood RNA - MAIT T-cell [nTPM]":"64.8","Blood RNA - memory B-cell [nTPM]":"63.9","Blood RNA - memory CD4 T-cell [nTPM]":"104.9","Blood RNA - memory CD8 T-cell [nTPM]":"56.6","Blood RNA - myeloid DC [nTPM]":"95.4","Blood RNA - naive B-cell [nTPM]":"59.6","Blood RNA - naive CD4 T-cell [nTPM]":"68.2","Blood RNA - naive CD8 T-cell [nTPM]":"41.4","Blood RNA - neutrophil [nTPM]":"134.3","Blood RNA - NK-cell [nTPM]":"92.5","Blood RNA - non-classical monocyte [nTPM]":"4.8","Blood RNA - plasmacytoid DC [nTPM]":"49.9","Blood RNA - T-reg [nTPM]":"298.2","Blood RNA - total PBMC [nTPM]":"53.5","Brain RNA - amygdala [nTPM]":"284.5","Brain RNA - basal ganglia [nTPM]":"310.8","Brain RNA - cerebellum [nTPM]":"329.0","Brain RNA - cerebral cortex [nTPM]":"365.1","Brain RNA - hippocampal formation [nTPM]":"288.2","Brain RNA - hypothalamus [nTPM]":"359.7","Brain RNA - medulla oblongata [nTPM]":"327.9","Brain RNA - midbrain [nTPM]":"340.2","Brain RNA - pons [nTPM]":"340.9","Brain RNA - spinal cord [nTPM]":"330.5","Brain RNA - thalamus [nTPM]":"337.0","Brain RNA - white matter [nTPM]":"315.6","Single Cell Type RNA - Adipocytes [nTPM]":"728.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"272.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"247.2","Single Cell Type RNA - Astrocytes [nTPM]":"32.3","Single Cell Type RNA - B-cells [nTPM]":"39.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"286.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1103.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"951.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.0","Single Cell Type RNA - Bipolar cells [nTPM]":"51.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"434.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"270.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"315.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"444.7","Single Cell Type RNA - Club cells [nTPM]":"569.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"242.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"553.5","Single Cell Type RNA - dendritic cells [nTPM]":"29.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"344.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"164.4","Single Cell Type RNA - Ductal cells [nTPM]":"1445.2","Single Cell Type RNA - Early spermatids [nTPM]":"129.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"94.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"91.6","Single Cell Type RNA - Endothelial cells [nTPM]":"792.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"166.6","Single Cell Type RNA - Erythroid cells [nTPM]":"206.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"618.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"407.2","Single Cell Type RNA - Fibroblasts [nTPM]":"303.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"109.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"115.6","Single Cell Type RNA - granulocytes [nTPM]":"139.4","Single Cell Type RNA - Granulosa cells [nTPM]":"88.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"585.0","Single Cell Type RNA - Hepatocytes [nTPM]":"185.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"486.7","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"112.8","Single Cell Type RNA - Ionocytes [nTPM]":"722.2","Single Cell Type RNA - Kupffer cells [nTPM]":"139.4","Single Cell Type RNA - Langerhans cells [nTPM]":"374.2","Single Cell Type RNA - Late spermatids [nTPM]":"61.6","Single Cell Type RNA - Leydig cells [nTPM]":"237.3","Single Cell Type RNA - Macrophages [nTPM]":"88.2","Single Cell Type RNA - Melanocytes [nTPM]":"1270.0","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"161.7","Single Cell Type RNA - Muller glia cells [nTPM]":"198.3","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1195.7","Single Cell Type RNA - Paneth cells [nTPM]":"392.2","Single Cell Type RNA - Peritubular cells [nTPM]":"204.7","Single Cell Type RNA - Plasma cells [nTPM]":"149.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1678.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"208.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1042.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.2","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"159.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"410.7","Single Cell Type RNA - Spermatocytes [nTPM]":"130.6","Single Cell Type RNA - Spermatogonia [nTPM]":"31.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"83.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"284.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"836.6","Single Cell Type RNA - T-cells [nTPM]":"52.4","Single Cell Type RNA - Theca cells [nTPM]":"139.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"104.9","Single Cell Type RNA - Urothelial cells [nTPM]":"1531.0"},{"Gene":"CD79A","Gene synonym":["IGA","MB-1"],"Ensembl":"ENSG00000105369","Gene description":"CD79a molecule","Uniprot":["P11912"],"Chromosome":"19","Position":"41877279-41881372","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"152.3","lymphoid tissue":"545.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"B-cells":"1186.4","Plasma cells":"956.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"38","RNA blood cell specific nTPM":{"memory B-cell":"1273.8","naive B-cell":"1457.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"B-cells":"1457.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"Daudi":"1598.7","REH":"491.0","U-698":"1366.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000019","HPA056444"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000019":"AB_2244527","HPA056444":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"213.4","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"47.2","Tissue RNA - breast [nTPM]":"9.5","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"3.6","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"47.3","Tissue RNA - duodenum [nTPM]":"37.9","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"482.4","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"3.7","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"28.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"28.5","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"152.3","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"286.5","Tissue RNA - stomach 1 [nTPM]":"76.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"93.7","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"545.2","Tissue RNA - urinary bladder [nTPM]":"32.3","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"1598.7","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"2.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"9.9","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"491.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"1.3","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.8","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"7.8","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"1366.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"52.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"12.4","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"6.9","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1273.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"1457.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"26.3","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"36.3","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"62.7","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1186.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"18.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"138.7","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"181.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"956.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"23.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CD79B","Gene synonym":["B29","IGB"],"Ensembl":"ENSG00000007312","Gene description":"CD79b molecule","Uniprot":["P40259"],"Chromosome":"17","Position":"63928740-63932336","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"266.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"491.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"1132.1","naive B-cell":"1505.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1505.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"1060.0","REH":"350.2","U-698":"1475.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009178","CAB009751","HPA044107"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB009751":"AB_2275844","HPA009178":"AB_1078483","HPA044107":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.35e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"70.5","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"54.6","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"12.3","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"3.4","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"266.7","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"25.3","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"7.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"66.2","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"147.7","Tissue RNA - stomach 1 [nTPM]":"10.7","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"27.1","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"208.4","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1060.0","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"2.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"56.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"23.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"350.2","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"4.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"1.7","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"51.3","Cell RNA - U-266\/84 [nTPM]":"54.4","Cell RNA - U-698 [nTPM]":"1475.5","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"6.2","Blood RNA - classical monocyte [nTPM]":"13.0","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"44.9","Blood RNA - intermediate monocyte [nTPM]":"192.2","Blood RNA - MAIT T-cell [nTPM]":"51.3","Blood RNA - memory B-cell [nTPM]":"1132.1","Blood RNA - memory CD4 T-cell [nTPM]":"57.1","Blood RNA - memory CD8 T-cell [nTPM]":"30.1","Blood RNA - myeloid DC [nTPM]":"47.0","Blood RNA - naive B-cell [nTPM]":"1505.8","Blood RNA - naive CD4 T-cell [nTPM]":"38.4","Blood RNA - naive CD8 T-cell [nTPM]":"23.2","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"42.4","Blood RNA - non-classical monocyte [nTPM]":"304.3","Blood RNA - plasmacytoid DC [nTPM]":"6.7","Blood RNA - T-reg [nTPM]":"107.9","Blood RNA - total PBMC [nTPM]":"112.1","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"24.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"491.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"24.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"25.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"13.4","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"14.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"99.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"27.0","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CD81","Gene synonym":["TAPA-1","TAPA1","TSPAN28"],"Ensembl":"ENSG00000110651","Gene description":"CD81 molecule","Uniprot":["P60033"],"Chromosome":"11","Position":"2376177-2397397","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1003.1","Endometrial stromal cells":"1050.9","Muller glia cells":"809.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"148.9","naive B-cell":"137.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"148.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"2960.6","fHDF\/TERT166":"1752.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002507","HPA007234"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"400000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002507":"AB_563639","HPA007234":"AB_1846333"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.56e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.21e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"892.1","Tissue RNA - adrenal gland [nTPM]":"299.1","Tissue RNA - amygdala [nTPM]":"560.6","Tissue RNA - appendix [nTPM]":"270.7","Tissue RNA - basal ganglia [nTPM]":"598.4","Tissue RNA - bone marrow [nTPM]":"77.8","Tissue RNA - breast [nTPM]":"773.6","Tissue RNA - cerebellum [nTPM]":"614.8","Tissue RNA - cerebral cortex [nTPM]":"590.2","Tissue RNA - cervix [nTPM]":"952.7","Tissue RNA - choroid plexus [nTPM]":"498.9","Tissue RNA - colon [nTPM]":"992.0","Tissue RNA - duodenum [nTPM]":"150.7","Tissue RNA - endometrium 1 [nTPM]":"1384.0","Tissue RNA - epididymis [nTPM]":"960.5","Tissue RNA - esophagus [nTPM]":"364.3","Tissue RNA - fallopian tube [nTPM]":"853.1","Tissue RNA - gallbladder [nTPM]":"534.5","Tissue RNA - heart muscle [nTPM]":"937.9","Tissue RNA - hippocampal formation [nTPM]":"511.1","Tissue RNA - hypothalamus [nTPM]":"615.8","Tissue RNA - kidney [nTPM]":"636.6","Tissue RNA - liver [nTPM]":"1175.7","Tissue RNA - lung [nTPM]":"768.4","Tissue RNA - lymph node [nTPM]":"429.0","Tissue RNA - medulla oblongata [nTPM]":"665.7","Tissue RNA - midbrain [nTPM]":"640.8","Tissue RNA - ovary [nTPM]":"656.8","Tissue RNA - pancreas [nTPM]":"449.5","Tissue RNA - parathyroid gland [nTPM]":"258.3","Tissue RNA - pituitary gland [nTPM]":"409.1","Tissue RNA - placenta [nTPM]":"441.0","Tissue RNA - pons [nTPM]":"651.1","Tissue RNA - prostate [nTPM]":"634.0","Tissue RNA - rectum [nTPM]":"234.4","Tissue RNA - retina [nTPM]":"75.9","Tissue RNA - salivary gland [nTPM]":"531.1","Tissue RNA - seminal vesicle [nTPM]":"1602.0","Tissue RNA - skeletal muscle [nTPM]":"214.3","Tissue RNA - skin 1 [nTPM]":"511.1","Tissue RNA - small intestine [nTPM]":"423.1","Tissue RNA - smooth muscle [nTPM]":"978.5","Tissue RNA - spinal cord [nTPM]":"694.1","Tissue RNA - spleen [nTPM]":"631.3","Tissue RNA - stomach 1 [nTPM]":"494.3","Tissue RNA - testis [nTPM]":"316.9","Tissue RNA - thalamus [nTPM]":"655.1","Tissue RNA - thymus [nTPM]":"158.9","Tissue RNA - thyroid gland [nTPM]":"564.6","Tissue RNA - tongue [nTPM]":"227.6","Tissue RNA - tonsil [nTPM]":"278.6","Tissue RNA - urinary bladder [nTPM]":"749.2","Tissue RNA - vagina [nTPM]":"763.4","Tissue RNA - white matter [nTPM]":"734.4","Cell RNA - A-431 [nTPM]":"337.0","Cell RNA - A549 [nTPM]":"342.0","Cell RNA - AF22 [nTPM]":"268.5","Cell RNA - AN3-CA [nTPM]":"413.4","Cell RNA - ASC diff [nTPM]":"2960.6","Cell RNA - ASC TERT1 [nTPM]":"1668.4","Cell RNA - BEWO [nTPM]":"224.8","Cell RNA - BJ [nTPM]":"621.0","Cell RNA - BJ hTERT+ [nTPM]":"1361.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"490.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"492.2","Cell RNA - CACO-2 [nTPM]":"322.8","Cell RNA - CAPAN-2 [nTPM]":"1.8","Cell RNA - Daudi [nTPM]":"285.4","Cell RNA - EFO-21 [nTPM]":"218.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1752.6","Cell RNA - GAMG [nTPM]":"312.5","Cell RNA - HaCaT [nTPM]":"430.5","Cell RNA - HAP1 [nTPM]":"167.3","Cell RNA - HBEC3-KT [nTPM]":"442.2","Cell RNA - HBF TERT88 [nTPM]":"199.9","Cell RNA - HDLM-2 [nTPM]":"135.6","Cell RNA - HEK 293 [nTPM]":"517.8","Cell RNA - HEL [nTPM]":"43.7","Cell RNA - HeLa [nTPM]":"117.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"976.4","Cell RNA - HL-60 [nTPM]":"188.2","Cell RNA - HMC-1 [nTPM]":"359.8","Cell RNA - HSkMC [nTPM]":"1222.3","Cell RNA - hTCEpi [nTPM]":"619.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"201.1","Cell RNA - hTERT-HME1 [nTPM]":"302.1","Cell RNA - hTERT-RPE1 [nTPM]":"757.9","Cell RNA - HUVEC TERT2 [nTPM]":"476.6","Cell RNA - JURKAT [nTPM]":"204.0","Cell RNA - K-562 [nTPM]":"198.7","Cell RNA - Karpas-707 [nTPM]":"484.9","Cell RNA - LHCN-M2 [nTPM]":"696.4","Cell RNA - MCF7 [nTPM]":"257.2","Cell RNA - MOLT-4 [nTPM]":"160.7","Cell RNA - NB-4 [nTPM]":"239.1","Cell RNA - NTERA-2 [nTPM]":"324.4","Cell RNA - OE19 [nTPM]":"304.7","Cell RNA - PC-3 [nTPM]":"274.2","Cell RNA - REH [nTPM]":"324.7","Cell RNA - RH-30 [nTPM]":"135.5","Cell RNA - RPMI-8226 [nTPM]":"183.3","Cell RNA - RPTEC TERT1 [nTPM]":"529.1","Cell RNA - RT4 [nTPM]":"223.3","Cell RNA - SCLC-21H [nTPM]":"288.8","Cell RNA - SH-SY5Y [nTPM]":"319.2","Cell RNA - SiHa [nTPM]":"198.4","Cell RNA - SK-BR-3 [nTPM]":"514.4","Cell RNA - SK-MEL-30 [nTPM]":"383.8","Cell RNA - SuSa [nTPM]":"214.3","Cell RNA - T-47d [nTPM]":"171.0","Cell RNA - THP-1 [nTPM]":"337.8","Cell RNA - TIME [nTPM]":"641.3","Cell RNA - U-138 MG [nTPM]":"249.0","Cell RNA - U-2 OS [nTPM]":"181.6","Cell RNA - U-2197 [nTPM]":"471.2","Cell RNA - U-251 MG [nTPM]":"216.6","Cell RNA - U-266\/70 [nTPM]":"356.9","Cell RNA - U-266\/84 [nTPM]":"88.1","Cell RNA - U-698 [nTPM]":"529.1","Cell RNA - U-87 MG [nTPM]":"361.3","Cell RNA - U-937 [nTPM]":"111.0","Cell RNA - WM-115 [nTPM]":"435.0","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"22.9","Blood RNA - gdT-cell [nTPM]":"21.1","Blood RNA - intermediate monocyte [nTPM]":"5.8","Blood RNA - MAIT T-cell [nTPM]":"34.4","Blood RNA - memory B-cell [nTPM]":"148.9","Blood RNA - memory CD4 T-cell [nTPM]":"14.9","Blood RNA - memory CD8 T-cell [nTPM]":"33.0","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"137.2","Blood RNA - naive CD4 T-cell [nTPM]":"9.2","Blood RNA - naive CD8 T-cell [nTPM]":"16.9","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"14.7","Blood RNA - non-classical monocyte [nTPM]":"7.3","Blood RNA - plasmacytoid DC [nTPM]":"7.7","Blood RNA - T-reg [nTPM]":"12.0","Blood RNA - total PBMC [nTPM]":"10.7","Brain RNA - amygdala [nTPM]":"560.6","Brain RNA - basal ganglia [nTPM]":"598.4","Brain RNA - cerebellum [nTPM]":"614.8","Brain RNA - cerebral cortex [nTPM]":"590.2","Brain RNA - hippocampal formation [nTPM]":"511.1","Brain RNA - hypothalamus [nTPM]":"615.8","Brain RNA - medulla oblongata [nTPM]":"665.7","Brain RNA - midbrain [nTPM]":"640.8","Brain RNA - pons [nTPM]":"651.1","Brain RNA - spinal cord [nTPM]":"694.1","Brain RNA - thalamus [nTPM]":"655.1","Brain RNA - white matter [nTPM]":"734.4","Single Cell Type RNA - Adipocytes [nTPM]":"1003.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"243.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"270.0","Single Cell Type RNA - Astrocytes [nTPM]":"95.0","Single Cell Type RNA - B-cells [nTPM]":"88.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"179.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"391.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"89.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"82.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"325.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"452.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"277.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"167.3","Single Cell Type RNA - Club cells [nTPM]":"102.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"207.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - dendritic cells [nTPM]":"267.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"105.7","Single Cell Type RNA - Early spermatids [nTPM]":"15.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"365.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1050.9","Single Cell Type RNA - Endothelial cells [nTPM]":"344.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.9","Single Cell Type RNA - Erythroid cells [nTPM]":"30.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"55.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.7","Single Cell Type RNA - Fibroblasts [nTPM]":"560.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"462.7","Single Cell Type RNA - granulocytes [nTPM]":"81.7","Single Cell Type RNA - Granulosa cells [nTPM]":"204.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"293.4","Single Cell Type RNA - Hepatocytes [nTPM]":"603.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"251.5","Single Cell Type RNA - Horizontal cells [nTPM]":"148.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"48.2","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"232.7","Single Cell Type RNA - Langerhans cells [nTPM]":"179.7","Single Cell Type RNA - Late spermatids [nTPM]":"50.2","Single Cell Type RNA - Leydig cells [nTPM]":"389.2","Single Cell Type RNA - Macrophages [nTPM]":"277.6","Single Cell Type RNA - Melanocytes [nTPM]":"151.2","Single Cell Type RNA - Microglial cells [nTPM]":"60.0","Single Cell Type RNA - monocytes [nTPM]":"23.0","Single Cell Type RNA - Muller glia cells [nTPM]":"809.2","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"145.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"93.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.3","Single Cell Type RNA - Paneth cells [nTPM]":"14.7","Single Cell Type RNA - Peritubular cells [nTPM]":"251.3","Single Cell Type RNA - Plasma cells [nTPM]":"50.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"147.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"85.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"76.1","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"356.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"423.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.6","Single Cell Type RNA - Spermatogonia [nTPM]":"19.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"164.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.1","Single Cell Type RNA - T-cells [nTPM]":"136.8","Single Cell Type RNA - Theca cells [nTPM]":"379.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.5","Single Cell Type RNA - Urothelial cells [nTPM]":"298.1"},{"Gene":"CD8A","Gene synonym":["CD8"],"Ensembl":"ENSG00000153563","Gene description":"CD8a molecule","Uniprot":["P01732"],"Chromosome":"2","Position":"86784610-86808396","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"lymphoid tissue":"369.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"111.7","T-cells":"242.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"MAIT T-cell":"234.4","memory CD8 T-cell":"523.0","naive CD8 T-cell":"476.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"T-cells":"523.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"4.0","MOLT-4":"15.2","RPMI-8226":"3.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000012","HPA037756","CAB075722"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"490000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 58: T-cells - T-cell receptor","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000012":"AB_2075537","CAB075722":"AB_2665709","HPA037756":"AB_2675648"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.54e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.15e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"21.2","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"22.5","Tissue RNA - breast [nTPM]":"4.7","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"1.4","Tissue RNA - colon [nTPM]":"4.9","Tissue RNA - duodenum [nTPM]":"11.8","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.1","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"7.4","Tissue RNA - lung [nTPM]":"10.5","Tissue RNA - lymph node [nTPM]":"45.0","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"20.7","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"117.1","Tissue RNA - stomach 1 [nTPM]":"16.4","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"369.0","Tissue RNA - thyroid gland [nTPM]":"4.4","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"21.4","Tissue RNA - urinary bladder [nTPM]":"9.1","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"15.2","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"3.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"30.0","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"234.4","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"523.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"476.8","Blood RNA - neutrophil [nTPM]":"4.3","Blood RNA - NK-cell [nTPM]":"27.9","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"152.4","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.1","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"111.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"11.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"6.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"5.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"30.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"242.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CDCA7","Gene synonym":["FLJ14736","JPO1"],"Ensembl":"ENSG00000144354","Gene description":"Cell division cycle associated 7","Uniprot":["Q9BWT1"],"Chromosome":"2","Position":"173354820-173368997","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"32.4","lymphoid tissue":"50.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"45.7","Intestinal goblet cells":"40.7","Leydig cells":"53.7","Undifferentiated cells":"124.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"43.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"7.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"279.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005565"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005565":"AB_2078680"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.50e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.7","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"13.1","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"2.4","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"25.5","Tissue RNA - duodenum [nTPM]":"30.7","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"37.5","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"29.5","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"11.7","Tissue RNA - small intestine [nTPM]":"32.4","Tissue RNA - smooth muscle [nTPM]":"3.4","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"14.3","Tissue RNA - testis [nTPM]":"6.0","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"50.1","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"41.2","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"6.7","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"44.2","Cell RNA - A549 [nTPM]":"33.3","Cell RNA - AF22 [nTPM]":"76.4","Cell RNA - AN3-CA [nTPM]":"83.3","Cell RNA - ASC diff [nTPM]":"3.6","Cell RNA - ASC TERT1 [nTPM]":"14.0","Cell RNA - BEWO [nTPM]":"79.9","Cell RNA - BJ [nTPM]":"26.0","Cell RNA - BJ hTERT+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"67.2","Cell RNA - CACO-2 [nTPM]":"51.6","Cell RNA - CAPAN-2 [nTPM]":"54.4","Cell RNA - Daudi [nTPM]":"122.1","Cell RNA - EFO-21 [nTPM]":"32.2","Cell RNA - fHDF\/TERT166 [nTPM]":"15.8","Cell RNA - GAMG [nTPM]":"23.5","Cell RNA - HaCaT [nTPM]":"45.0","Cell RNA - HAP1 [nTPM]":"122.4","Cell RNA - HBEC3-KT [nTPM]":"46.6","Cell RNA - HBF TERT88 [nTPM]":"87.0","Cell RNA - HDLM-2 [nTPM]":"59.2","Cell RNA - HEK 293 [nTPM]":"67.4","Cell RNA - HEL [nTPM]":"27.6","Cell RNA - HeLa [nTPM]":"24.6","Cell RNA - Hep G2 [nTPM]":"66.0","Cell RNA - HHSteC [nTPM]":"3.8","Cell RNA - HL-60 [nTPM]":"181.2","Cell RNA - HMC-1 [nTPM]":"25.1","Cell RNA - HSkMC [nTPM]":"11.4","Cell RNA - hTCEpi [nTPM]":"3.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.8","Cell RNA - hTERT-HME1 [nTPM]":"27.3","Cell RNA - hTERT-RPE1 [nTPM]":"7.8","Cell RNA - HUVEC TERT2 [nTPM]":"28.0","Cell RNA - JURKAT [nTPM]":"158.1","Cell RNA - K-562 [nTPM]":"67.4","Cell RNA - Karpas-707 [nTPM]":"27.2","Cell RNA - LHCN-M2 [nTPM]":"17.7","Cell RNA - MCF7 [nTPM]":"35.4","Cell RNA - MOLT-4 [nTPM]":"279.7","Cell RNA - NB-4 [nTPM]":"181.7","Cell RNA - NTERA-2 [nTPM]":"90.4","Cell RNA - OE19 [nTPM]":"103.4","Cell RNA - PC-3 [nTPM]":"22.7","Cell RNA - REH [nTPM]":"194.4","Cell RNA - RH-30 [nTPM]":"58.2","Cell RNA - RPMI-8226 [nTPM]":"77.3","Cell RNA - RPTEC TERT1 [nTPM]":"29.5","Cell RNA - RT4 [nTPM]":"38.2","Cell RNA - SCLC-21H [nTPM]":"22.3","Cell RNA - SH-SY5Y [nTPM]":"39.2","Cell RNA - SiHa [nTPM]":"40.8","Cell RNA - SK-BR-3 [nTPM]":"13.4","Cell RNA - SK-MEL-30 [nTPM]":"22.0","Cell RNA - SuSa [nTPM]":"67.9","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"70.5","Cell RNA - TIME [nTPM]":"13.0","Cell RNA - U-138 MG [nTPM]":"39.3","Cell RNA - U-2 OS [nTPM]":"16.8","Cell RNA - U-2197 [nTPM]":"12.9","Cell RNA - U-251 MG [nTPM]":"48.5","Cell RNA - U-266\/70 [nTPM]":"7.4","Cell RNA - U-266\/84 [nTPM]":"17.1","Cell RNA - U-698 [nTPM]":"173.0","Cell RNA - U-87 MG [nTPM]":"24.4","Cell RNA - U-937 [nTPM]":"99.8","Cell RNA - WM-115 [nTPM]":"34.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"5.9","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"7.9","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.7","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.2","Single Cell Type RNA - Erythroid cells [nTPM]":"33.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.9","Single Cell Type RNA - Fibroblasts [nTPM]":"4.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"53.7","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"3.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"13.8","Single Cell Type RNA - Spermatogonia [nTPM]":"28.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.1","Single Cell Type RNA - T-cells [nTPM]":"9.1","Single Cell Type RNA - Theca cells [nTPM]":"2.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"124.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"CEBPE","Gene synonym":["CRP1"],"Ensembl":"ENSG00000092067","Gene description":"CCAAT enhancer binding protein epsilon","Uniprot":["Q15744"],"Chromosome":"14","Position":"23117306-23119255","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"bone marrow":"51.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"6.6","Kupffer cells":"1.4","Macrophages":"2.3","monocytes":"2.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"218","RNA blood cell specific nTPM":{"eosinophil":"750.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"250","RNA blood lineage specific nTPM":{"granulocytes":"750.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HL-60":"233.8","NB-4":"122.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002928","CAB005113"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB005113":"AB_631240","HPA002928":"AB_1078494"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"51.8","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"3.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"3.4","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"233.8","Cell RNA - HMC-1 [nTPM]":"39.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"9.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"122.5","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"10.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"18.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"26.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"750.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CFB","Gene synonym":["BF","BFD","H2-Bf"],"Ensembl":"ENSG00000243649","Gene description":"Complement factor B","Uniprot":["P00751"],"Chromosome":"6","Position":"31945650-31952084","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"liver":"2613.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"873.6","Exocrine glandular cells":"197.3","Hepatocytes":"284.0","Pancreatic endocrine cells":"318.0","Proximal enterocytes":"139.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"78.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"15.0","ASC TERT1":"23.0","EFO-21":"25.1","fHDF\/TERT166":"14.1","HSkMC":"19.1","U-87 MG":"10.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000951","HPA001817","HPA001832","CAB016381"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles","Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":879000000,"Blood concentration - Conc. blood MS [pg\/L]":"120000000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB016381":"AB_627562","HPA000951":"AB_2797216","HPA001817":"AB_1078779","HPA001832":"AB_1078778"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"143.7","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"32.8","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"28.5","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"9.9","Tissue RNA - cervix [nTPM]":"16.3","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"28.1","Tissue RNA - endometrium 1 [nTPM]":"8.2","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"53.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"42.6","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"58.7","Tissue RNA - liver [nTPM]":"2613.2","Tissue RNA - lung [nTPM]":"39.2","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"4.1","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"9.9","Tissue RNA - pancreas [nTPM]":"51.8","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"17.7","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"60.3","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"43.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"73.1","Tissue RNA - smooth muscle [nTPM]":"48.3","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"54.5","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"6.7","Tissue RNA - urinary bladder [nTPM]":"17.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"15.0","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"25.1","Cell RNA - fHDF\/TERT166 [nTPM]":"14.1","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"19.1","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"1.0","Cell RNA - U-87 MG [nTPM]":"10.1","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"9.9","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.1","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"64.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"127.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"873.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"197.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"284.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"18.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"318.0","Single Cell Type RNA - Paneth cells [nTPM]":"10.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"75.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"CFD","Gene synonym":["ADN","DF","PFD"],"Ensembl":"ENSG00000197766","Gene description":"Complement factor D","Uniprot":["P00746"],"Chromosome":"19","Position":"859664-863641","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"1496.7","breast":"993.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Fibroblasts":"9365.5","Leydig cells":"5032.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"297.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"297.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"ASC diff":"197.4","THP-1":"342.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":732000000,"Blood concentration - Conc. blood MS [pg\/L]":"4400000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.77e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.09e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"1496.7","Tissue RNA - adrenal gland [nTPM]":"33.3","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"993.2","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"597.4","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"324.8","Tissue RNA - duodenum [nTPM]":"23.5","Tissue RNA - endometrium 1 [nTPM]":"58.4","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"212.8","Tissue RNA - fallopian tube [nTPM]":"258.0","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"854.2","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"18.1","Tissue RNA - liver [nTPM]":"8.7","Tissue RNA - lung [nTPM]":"363.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"74.3","Tissue RNA - pancreas [nTPM]":"41.4","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"14.5","Tissue RNA - pons [nTPM]":"3.6","Tissue RNA - prostate [nTPM]":"277.8","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"247.3","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"197.0","Tissue RNA - skin 1 [nTPM]":"488.6","Tissue RNA - small intestine [nTPM]":"248.4","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"28.6","Tissue RNA - stomach 1 [nTPM]":"263.8","Tissue RNA - testis [nTPM]":"51.8","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"332.3","Tissue RNA - tongue [nTPM]":"26.9","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"848.3","Tissue RNA - vagina [nTPM]":"729.8","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"2.2","Cell RNA - ASC diff [nTPM]":"197.4","Cell RNA - ASC TERT1 [nTPM]":"26.2","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"14.5","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"12.3","Cell RNA - Hep G2 [nTPM]":"3.8","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"4.9","Cell RNA - HSkMC [nTPM]":"8.7","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.5","Cell RNA - K-562 [nTPM]":"11.9","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.6","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"49.2","Cell RNA - NTERA-2 [nTPM]":"1.0","Cell RNA - OE19 [nTPM]":"4.5","Cell RNA - PC-3 [nTPM]":"16.1","Cell RNA - REH [nTPM]":"1.3","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"5.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"342.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"5.1","Cell RNA - U-2197 [nTPM]":"2.9","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"7.8","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"20.8","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"297.6","Blood RNA - classical monocyte [nTPM]":"41.2","Blood RNA - eosinophil [nTPM]":"127.8","Blood RNA - gdT-cell [nTPM]":"8.4","Blood RNA - intermediate monocyte [nTPM]":"55.5","Blood RNA - MAIT T-cell [nTPM]":"13.2","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.2","Blood RNA - memory CD8 T-cell [nTPM]":"10.2","Blood RNA - myeloid DC [nTPM]":"14.5","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"9.7","Blood RNA - neutrophil [nTPM]":"112.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"57.3","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"37.8","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"3.6","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"857.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"19.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"785.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"107.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"120.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"30.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.6","Single Cell Type RNA - dendritic cells [nTPM]":"40.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"7.7","Single Cell Type RNA - Early spermatids [nTPM]":"27.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"593.3","Single Cell Type RNA - Endothelial cells [nTPM]":"114.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.9","Single Cell Type RNA - Fibroblasts [nTPM]":"9365.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"113.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.9","Single Cell Type RNA - granulocytes [nTPM]":"17.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"272.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"424.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1145.2","Single Cell Type RNA - Late spermatids [nTPM]":"89.6","Single Cell Type RNA - Leydig cells [nTPM]":"5032.4","Single Cell Type RNA - Macrophages [nTPM]":"442.5","Single Cell Type RNA - Melanocytes [nTPM]":"642.1","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"303.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"64.8","Single Cell Type RNA - Peritubular cells [nTPM]":"283.2","Single Cell Type RNA - Plasma cells [nTPM]":"41.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"414.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"530.2","Single Cell Type RNA - Spermatocytes [nTPM]":"11.4","Single Cell Type RNA - Spermatogonia [nTPM]":"21.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"735.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - T-cells [nTPM]":"82.8","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.0","Single Cell Type RNA - Urothelial cells [nTPM]":"233.2"},{"Gene":"CFH","Gene synonym":["ARMD4","ARMS1","FHL1","HF","HF1","HF2","HUS"],"Ensembl":"ENSG00000000971","Gene description":"Complement factor H","Uniprot":["P08603"],"Chromosome":"1","Position":"196652043-196747504","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Age-related macular degeneration","Cancer-related genes","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"liver":"1676.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Fibroblasts":"448.0","Hepatocytes":"1114.8","Leydig cells":"283.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"liver cancer":"151.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"18.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"T-cells":"18.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"123.1","HSkMC":"119.5","hTERT-RPE1":"374.9","RT4":"227.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016385","CAB016769","HPA038922","HPA049176","HPA053326"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":396000000000,"Blood concentration - Conc. blood MS [pg\/L]":"100000000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB016385":"AB_627572","CAB016769":null,"HPA038922":"AB_2676271","HPA049176":"AB_2680663","HPA053326":"AB_2682113"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.92e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Tissue RNA - adipose tissue [nTPM]":"125.3","Tissue RNA - adrenal gland [nTPM]":"42.1","Tissue RNA - amygdala [nTPM]":"18.1","Tissue RNA - appendix [nTPM]":"32.7","Tissue RNA - basal ganglia [nTPM]":"21.5","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"66.9","Tissue RNA - cerebellum [nTPM]":"20.0","Tissue RNA - cerebral cortex [nTPM]":"29.6","Tissue RNA - cervix [nTPM]":"76.8","Tissue RNA - choroid plexus [nTPM]":"43.0","Tissue RNA - colon [nTPM]":"51.0","Tissue RNA - duodenum [nTPM]":"30.5","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"15.9","Tissue RNA - esophagus [nTPM]":"63.8","Tissue RNA - fallopian tube [nTPM]":"24.2","Tissue RNA - gallbladder [nTPM]":"133.6","Tissue RNA - heart muscle [nTPM]":"301.5","Tissue RNA - hippocampal formation [nTPM]":"18.1","Tissue RNA - hypothalamus [nTPM]":"18.6","Tissue RNA - kidney [nTPM]":"25.5","Tissue RNA - liver [nTPM]":"1676.3","Tissue RNA - lung [nTPM]":"70.8","Tissue RNA - lymph node [nTPM]":"27.4","Tissue RNA - medulla oblongata [nTPM]":"19.3","Tissue RNA - midbrain [nTPM]":"19.0","Tissue RNA - ovary [nTPM]":"165.1","Tissue RNA - pancreas [nTPM]":"14.0","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"16.0","Tissue RNA - placenta [nTPM]":"26.1","Tissue RNA - pons [nTPM]":"19.9","Tissue RNA - prostate [nTPM]":"23.0","Tissue RNA - rectum [nTPM]":"80.2","Tissue RNA - retina [nTPM]":"4.3","Tissue RNA - salivary gland [nTPM]":"126.7","Tissue RNA - seminal vesicle [nTPM]":"24.0","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"74.5","Tissue RNA - small intestine [nTPM]":"52.1","Tissue RNA - smooth muscle [nTPM]":"32.5","Tissue RNA - spinal cord [nTPM]":"19.5","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"46.9","Tissue RNA - testis [nTPM]":"14.3","Tissue RNA - thalamus [nTPM]":"21.6","Tissue RNA - thymus [nTPM]":"12.1","Tissue RNA - thyroid gland [nTPM]":"102.5","Tissue RNA - tongue [nTPM]":"84.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"149.9","Tissue RNA - vagina [nTPM]":"27.0","Tissue RNA - white matter [nTPM]":"21.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"64.9","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"96.5","Cell RNA - ASC TERT1 [nTPM]":"54.7","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"25.8","Cell RNA - BJ hTERT+ [nTPM]":"63.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.5","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"11.9","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"9.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"23.6","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"20.0","Cell RNA - HeLa [nTPM]":"74.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"123.1","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"119.5","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.4","Cell RNA - hTERT-HME1 [nTPM]":"7.9","Cell RNA - hTERT-RPE1 [nTPM]":"374.9","Cell RNA - HUVEC TERT2 [nTPM]":"79.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"74.4","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"89.4","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"89.8","Cell RNA - RPMI-8226 [nTPM]":"21.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"227.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"73.6","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"13.1","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"18.7","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"18.1","Brain RNA - basal ganglia [nTPM]":"21.5","Brain RNA - cerebellum [nTPM]":"20.0","Brain RNA - cerebral cortex [nTPM]":"29.6","Brain RNA - hippocampal formation [nTPM]":"18.1","Brain RNA - hypothalamus [nTPM]":"18.6","Brain RNA - medulla oblongata [nTPM]":"19.3","Brain RNA - midbrain [nTPM]":"19.0","Brain RNA - pons [nTPM]":"19.9","Brain RNA - spinal cord [nTPM]":"19.5","Brain RNA - thalamus [nTPM]":"21.6","Brain RNA - white matter [nTPM]":"21.1","Single Cell Type RNA - Adipocytes [nTPM]":"73.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"4.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"63.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"140.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"141.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"49.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"52.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"448.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.9","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"6.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1114.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"43.8","Single Cell Type RNA - Langerhans cells [nTPM]":"62.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"283.9","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"138.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"115.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"94.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"59.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"26.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"61.5"},{"Gene":"CFI","Gene synonym":["C3b-INA","FI","IF","KAF"],"Ensembl":"ENSG00000205403","Gene description":"Complement factor I","Uniprot":["P05156"],"Chromosome":"4","Position":"109740694-109801999","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Age-related macular degeneration","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"liver":"1098.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"108.7","Hepatocytes":"592.5","Muller glia cells":"147.8","Proximal tubular cells":"223.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"90.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"106.1","Hep G2":"179.8","HSkMC":"67.4","RPTEC TERT1":"190.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001143","CAB016777","HPA024061"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016777":null,"HPA001143":"AB_1078555","HPA024061":"AB_1847129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.06e-4"},"Tissue RNA - adipose tissue [nTPM]":"45.1","Tissue RNA - adrenal gland [nTPM]":"50.2","Tissue RNA - amygdala [nTPM]":"8.1","Tissue RNA - appendix [nTPM]":"12.6","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"17.4","Tissue RNA - cerebellum [nTPM]":"7.7","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"36.8","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"38.0","Tissue RNA - endometrium 1 [nTPM]":"39.2","Tissue RNA - epididymis [nTPM]":"80.3","Tissue RNA - esophagus [nTPM]":"9.3","Tissue RNA - fallopian tube [nTPM]":"74.0","Tissue RNA - gallbladder [nTPM]":"73.0","Tissue RNA - heart muscle [nTPM]":"25.0","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"224.9","Tissue RNA - liver [nTPM]":"1098.8","Tissue RNA - lung [nTPM]":"50.7","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"32.1","Tissue RNA - pancreas [nTPM]":"26.0","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"8.4","Tissue RNA - placenta [nTPM]":"24.1","Tissue RNA - pons [nTPM]":"10.7","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"53.0","Tissue RNA - salivary gland [nTPM]":"15.0","Tissue RNA - seminal vesicle [nTPM]":"26.7","Tissue RNA - skeletal muscle [nTPM]":"3.9","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"22.3","Tissue RNA - smooth muscle [nTPM]":"24.3","Tissue RNA - spinal cord [nTPM]":"10.5","Tissue RNA - spleen [nTPM]":"33.1","Tissue RNA - stomach 1 [nTPM]":"14.4","Tissue RNA - testis [nTPM]":"8.8","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"7.5","Tissue RNA - urinary bladder [nTPM]":"34.1","Tissue RNA - vagina [nTPM]":"8.3","Tissue RNA - white matter [nTPM]":"10.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"106.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"32.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"34.8","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"179.8","Cell RNA - HHSteC [nTPM]":"6.2","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"67.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"190.6","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"18.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"8.1","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"7.7","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"10.7","Brain RNA - spinal cord [nTPM]":"10.5","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"10.6","Single Cell Type RNA - Adipocytes [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"50.9","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"4.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"108.7","Single Cell Type RNA - Club cells [nTPM]":"36.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"64.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"69.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.4","Single Cell Type RNA - Endothelial cells [nTPM]":"57.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"34.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"72.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.0","Single Cell Type RNA - Hepatocytes [nTPM]":"592.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"147.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"223.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"18.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"CFP","Gene synonym":["PFC"],"Ensembl":"ENSG00000126759","Gene description":"Complement factor properdin","Uniprot":["P27918"],"Chromosome":"X","Position":"47623172-47630305","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"83.9","lymphoid tissue":"58.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatic stellate cells":"108.1","Kupffer cells":"356.7","Langerhans cells":"164.1","Macrophages":"177.3","monocytes":"473.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"classical monocyte":"1167.5","intermediate monocyte":"1273.6","myeloid DC":"994.5","neutrophil":"730.3","non-classical monocyte":"868.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"46","RNA blood lineage specific nTPM":{"dendritic cells":"994.5","granulocytes":"730.3","monocytes":"1273.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"20.7","HEL":"5.0","HMC-1":"5.5","NB-4":"10.7","U-937":"7.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072644"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6200000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA072644":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.0","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"20.5","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"83.9","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"3.4","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"12.0","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"1.5","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"5.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"58.4","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"20.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"5.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"5.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"10.7","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"7.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"131.5","Blood RNA - classical monocyte [nTPM]":"1167.5","Blood RNA - eosinophil [nTPM]":"39.9","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"1273.6","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"15.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"994.5","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"21.8","Blood RNA - naive CD8 T-cell [nTPM]":"8.1","Blood RNA - neutrophil [nTPM]":"730.3","Blood RNA - NK-cell [nTPM]":"12.3","Blood RNA - non-classical monocyte [nTPM]":"868.9","Blood RNA - plasmacytoid DC [nTPM]":"30.9","Blood RNA - T-reg [nTPM]":"14.1","Blood RNA - total PBMC [nTPM]":"1071.9","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"108.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"356.7","Single Cell Type RNA - Langerhans cells [nTPM]":"164.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"177.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"473.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CIITA","Gene synonym":["C2TA","MHC2TA","NLRA"],"Ensembl":"ENSG00000179583","Gene description":"Class II major histocompatibility complex transactivator","Uniprot":["P33076"],"Chromosome":"16","Position":"10866222-10943021","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"57.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"48.8","Langerhans cells":"51.8","Macrophages":"43.8","Microglial cells":"42.2","monocytes":"51.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"classical monocyte":"29.1","eosinophil":"17.5","intermediate monocyte":"23.5","memory B-cell":"47.3","myeloid DC":"46.2","naive B-cell":"63.3","non-classical monocyte":"29.0","plasmacytoid DC":"48.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"51.1","REH":"89.5","U-266\/70":"18.0","U-698":"25.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016084","HPA054757"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016084":"AB_627261","HPA054757":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"6.5","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"39.2","Tissue RNA - basal ganglia [nTPM]":"5.9","Tissue RNA - bone marrow [nTPM]":"9.2","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"7.3","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"8.9","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"20.5","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"15.0","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"5.4","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"24.1","Tissue RNA - lymph node [nTPM]":"57.3","Tissue RNA - medulla oblongata [nTPM]":"15.0","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"11.9","Tissue RNA - prostate [nTPM]":"4.8","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"8.7","Tissue RNA - small intestine [nTPM]":"24.8","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"51.2","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"13.0","Tissue RNA - thymus [nTPM]":"15.9","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"57.0","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"11.2","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.7","Cell RNA - HaCaT [nTPM]":"1.8","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"51.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"6.3","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"2.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"89.5","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"7.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"3.6","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"3.8","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"4.3","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"18.0","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"16.0","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"29.1","Blood RNA - eosinophil [nTPM]":"17.5","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"23.5","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"47.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"46.2","Blood RNA - naive B-cell [nTPM]":"63.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"6.8","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"29.0","Blood RNA - plasmacytoid DC [nTPM]":"48.3","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"5.4","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"5.9","Brain RNA - cerebellum [nTPM]":"7.3","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"5.4","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"15.0","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"11.9","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"13.0","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"14.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"48.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"17.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"7.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"16.1","Single Cell Type RNA - Langerhans cells [nTPM]":"51.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"43.8","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"51.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"CORO1A","Gene synonym":["coronin-1","HCORO1","p57"],"Ensembl":"ENSG00000102879","Gene description":"Coronin 1A","Uniprot":["P31146"],"Chromosome":"16","Position":"30182827-30189076","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"568.8","lymphoid tissue":"583.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"523.9","dendritic cells":"588.7","Hofbauer cells":"494.4","Kupffer cells":"395.8","Macrophages":"342.7","monocytes":"583.7","NK-cells":"968.1","T-cells":"663.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"924.0","HL-60":"645.7","HMC-1":"1086.7","JURKAT":"603.0","MOLT-4":"632.5","NB-4":"771.8","RPMI-8226":"980.9","U-698":"618.2","U-937":"829.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB046473","HPA051132"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"45000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB046473":"AB_10602363","HPA051132":"AB_2681355"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.91e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.42e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.27e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.74e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"29.1","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"34.4","Tissue RNA - appendix [nTPM]":"306.4","Tissue RNA - basal ganglia [nTPM]":"37.1","Tissue RNA - bone marrow [nTPM]":"568.8","Tissue RNA - breast [nTPM]":"11.2","Tissue RNA - cerebellum [nTPM]":"24.9","Tissue RNA - cerebral cortex [nTPM]":"52.0","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"23.6","Tissue RNA - colon [nTPM]":"26.8","Tissue RNA - duodenum [nTPM]":"44.3","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"22.5","Tissue RNA - fallopian tube [nTPM]":"17.9","Tissue RNA - gallbladder [nTPM]":"45.0","Tissue RNA - heart muscle [nTPM]":"11.3","Tissue RNA - hippocampal formation [nTPM]":"36.9","Tissue RNA - hypothalamus [nTPM]":"31.9","Tissue RNA - kidney [nTPM]":"11.5","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"49.5","Tissue RNA - lymph node [nTPM]":"583.8","Tissue RNA - medulla oblongata [nTPM]":"37.6","Tissue RNA - midbrain [nTPM]":"32.0","Tissue RNA - ovary [nTPM]":"6.4","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"18.4","Tissue RNA - pons [nTPM]":"32.2","Tissue RNA - prostate [nTPM]":"11.4","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"32.9","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"111.0","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"35.8","Tissue RNA - spleen [nTPM]":"321.4","Tissue RNA - stomach 1 [nTPM]":"49.0","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"33.9","Tissue RNA - thymus [nTPM]":"257.6","Tissue RNA - thyroid gland [nTPM]":"12.7","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"309.1","Tissue RNA - urinary bladder [nTPM]":"57.6","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"50.0","Cell RNA - A-431 [nTPM]":"3.1","Cell RNA - A549 [nTPM]":"3.6","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"21.5","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"6.1","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"6.9","Cell RNA - Daudi [nTPM]":"924.0","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"1.5","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"5.2","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"302.3","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"97.9","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"15.0","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"645.7","Cell RNA - HMC-1 [nTPM]":"1086.7","Cell RNA - HSkMC [nTPM]":"2.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.3","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"603.0","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"467.6","Cell RNA - LHCN-M2 [nTPM]":"3.4","Cell RNA - MCF7 [nTPM]":"80.7","Cell RNA - MOLT-4 [nTPM]":"632.5","Cell RNA - NB-4 [nTPM]":"771.8","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"3.1","Cell RNA - PC-3 [nTPM]":"6.4","Cell RNA - REH [nTPM]":"340.0","Cell RNA - RH-30 [nTPM]":"17.5","Cell RNA - RPMI-8226 [nTPM]":"980.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.3","Cell RNA - RT4 [nTPM]":"5.1","Cell RNA - SCLC-21H [nTPM]":"17.3","Cell RNA - SH-SY5Y [nTPM]":"13.0","Cell RNA - SiHa [nTPM]":"2.2","Cell RNA - SK-BR-3 [nTPM]":"110.7","Cell RNA - SK-MEL-30 [nTPM]":"2.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"373.0","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"4.0","Cell RNA - U-2 OS [nTPM]":"9.0","Cell RNA - U-2197 [nTPM]":"2.7","Cell RNA - U-251 MG [nTPM]":"3.1","Cell RNA - U-266\/70 [nTPM]":"348.5","Cell RNA - U-266\/84 [nTPM]":"497.7","Cell RNA - U-698 [nTPM]":"618.2","Cell RNA - U-87 MG [nTPM]":"3.0","Cell RNA - U-937 [nTPM]":"829.6","Cell RNA - WM-115 [nTPM]":"6.3","Blood RNA - basophil [nTPM]":"797.2","Blood RNA - classical monocyte [nTPM]":"773.6","Blood RNA - eosinophil [nTPM]":"2671.1","Blood RNA - gdT-cell [nTPM]":"637.5","Blood RNA - intermediate monocyte [nTPM]":"859.7","Blood RNA - MAIT T-cell [nTPM]":"597.8","Blood RNA - memory B-cell [nTPM]":"505.5","Blood RNA - memory CD4 T-cell [nTPM]":"567.3","Blood RNA - memory CD8 T-cell [nTPM]":"625.6","Blood RNA - myeloid DC [nTPM]":"843.2","Blood RNA - naive B-cell [nTPM]":"512.0","Blood RNA - naive CD4 T-cell [nTPM]":"537.1","Blood RNA - naive CD8 T-cell [nTPM]":"566.2","Blood RNA - neutrophil [nTPM]":"1318.9","Blood RNA - NK-cell [nTPM]":"531.0","Blood RNA - non-classical monocyte [nTPM]":"898.0","Blood RNA - plasmacytoid DC [nTPM]":"482.1","Blood RNA - T-reg [nTPM]":"858.7","Blood RNA - total PBMC [nTPM]":"1647.2","Brain RNA - amygdala [nTPM]":"34.4","Brain RNA - basal ganglia [nTPM]":"37.1","Brain RNA - cerebellum [nTPM]":"24.9","Brain RNA - cerebral cortex [nTPM]":"52.0","Brain RNA - hippocampal formation [nTPM]":"36.9","Brain RNA - hypothalamus [nTPM]":"31.9","Brain RNA - medulla oblongata [nTPM]":"37.6","Brain RNA - midbrain [nTPM]":"32.0","Brain RNA - pons [nTPM]":"32.2","Brain RNA - spinal cord [nTPM]":"35.8","Brain RNA - thalamus [nTPM]":"33.9","Brain RNA - white matter [nTPM]":"50.0","Single Cell Type RNA - Adipocytes [nTPM]":"6.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"523.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"6.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.6","Single Cell Type RNA - dendritic cells [nTPM]":"588.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"12.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"60.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"83.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"494.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"395.8","Single Cell Type RNA - Langerhans cells [nTPM]":"197.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"342.7","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"583.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"968.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.1","Single Cell Type RNA - Paneth cells [nTPM]":"47.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"201.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"663.0","Single Cell Type RNA - Theca cells [nTPM]":"2.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"CR2","Gene synonym":["C3DR","CD21"],"Ensembl":"ENSG00000117322","Gene description":"Complement C3d receptor 2","Uniprot":["P20023"],"Chromosome":"1","Position":"207454230-207489895","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"lymphoid tissue":"174.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nTPM":{"B-cells":"54.9","Plasma cells":"14.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"7.1","stomach cancer":"5.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"memory B-cell":"17.5","naive B-cell":"20.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"B-cells":"20.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"24.0","JURKAT":"4.0","MOLT-4":"13.4","RPMI-8226":"4.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002659","HPA052942","HPA060715"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000000","Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002659":null,"HPA052942":"AB_2681994","HPA060715":"AB_2684349"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.90e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"53.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"174.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"73.2","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"15.2","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"171.0","Tissue RNA - urinary bladder [nTPM]":"1.9","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"24.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"13.4","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"3.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"17.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"20.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"54.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CTLA4","Gene synonym":["CD","CD152","CELIAC3","CTLA-4","GSE","IDDM12"],"Ensembl":"ENSG00000163599","Gene description":"Cytotoxic T-lymphocyte associated protein 4","Uniprot":["P16410"],"Chromosome":"2","Position":"203867771-203873965","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Diabetes mellitus","Disease variant","FDA approved drug targets","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"37.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"T-cells":"41.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"T-reg":"44.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"445","RNA blood lineage specific nTPM":{"T-cells":"44.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"1.5","SK-MEL-30":"3.0","U-266\/70":"4.3","U-266\/84":"13.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.89e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.48e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"18.5","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"37.4","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"4.3","Cell RNA - U-266\/84 [nTPM]":"13.5","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"44.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"41.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CTPS1","Gene synonym":["CTPS","GATD5"],"Ensembl":"ENSG00000171793","Gene description":"CTP synthase 1","Uniprot":["P17812"],"Chromosome":"1","Position":"40979688-41012565","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Pyrimidine biosynthesis"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"73.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017111","HPA051322"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB017111":null,"HPA051322":"AB_2681441"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"8.1","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"11.1","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"8.7","Tissue RNA - duodenum [nTPM]":"4.4","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"14.9","Tissue RNA - fallopian tube [nTPM]":"11.1","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"73.4","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"47.6","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"5.8","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"50.6","Tissue RNA - seminal vesicle [nTPM]":"24.8","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"8.4","Tissue RNA - smooth muscle [nTPM]":"51.9","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"14.7","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"17.8","Tissue RNA - urinary bladder [nTPM]":"17.7","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"77.8","Cell RNA - A549 [nTPM]":"68.5","Cell RNA - AF22 [nTPM]":"95.3","Cell RNA - AN3-CA [nTPM]":"60.5","Cell RNA - ASC diff [nTPM]":"22.9","Cell RNA - ASC TERT1 [nTPM]":"30.9","Cell RNA - BEWO [nTPM]":"138.5","Cell RNA - BJ [nTPM]":"138.8","Cell RNA - BJ hTERT+ [nTPM]":"57.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"141.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"92.0","Cell RNA - CACO-2 [nTPM]":"131.5","Cell RNA - CAPAN-2 [nTPM]":"66.6","Cell RNA - Daudi [nTPM]":"149.8","Cell RNA - EFO-21 [nTPM]":"55.6","Cell RNA - fHDF\/TERT166 [nTPM]":"61.7","Cell RNA - GAMG [nTPM]":"39.4","Cell RNA - HaCaT [nTPM]":"38.6","Cell RNA - HAP1 [nTPM]":"91.5","Cell RNA - HBEC3-KT [nTPM]":"97.0","Cell RNA - HBF TERT88 [nTPM]":"139.5","Cell RNA - HDLM-2 [nTPM]":"66.5","Cell RNA - HEK 293 [nTPM]":"78.0","Cell RNA - HEL [nTPM]":"87.3","Cell RNA - HeLa [nTPM]":"72.3","Cell RNA - Hep G2 [nTPM]":"43.3","Cell RNA - HHSteC [nTPM]":"87.8","Cell RNA - HL-60 [nTPM]":"128.0","Cell RNA - HMC-1 [nTPM]":"56.8","Cell RNA - HSkMC [nTPM]":"34.0","Cell RNA - hTCEpi [nTPM]":"49.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"148.5","Cell RNA - hTERT-HME1 [nTPM]":"103.0","Cell RNA - hTERT-RPE1 [nTPM]":"23.0","Cell RNA - HUVEC TERT2 [nTPM]":"64.1","Cell RNA - JURKAT [nTPM]":"102.2","Cell RNA - K-562 [nTPM]":"84.7","Cell RNA - Karpas-707 [nTPM]":"51.5","Cell RNA - LHCN-M2 [nTPM]":"99.4","Cell RNA - MCF7 [nTPM]":"42.9","Cell RNA - MOLT-4 [nTPM]":"125.0","Cell RNA - NB-4 [nTPM]":"38.1","Cell RNA - NTERA-2 [nTPM]":"126.8","Cell RNA - OE19 [nTPM]":"66.4","Cell RNA - PC-3 [nTPM]":"81.3","Cell RNA - REH [nTPM]":"100.9","Cell RNA - RH-30 [nTPM]":"120.0","Cell RNA - RPMI-8226 [nTPM]":"93.7","Cell RNA - RPTEC TERT1 [nTPM]":"71.4","Cell RNA - RT4 [nTPM]":"69.4","Cell RNA - SCLC-21H [nTPM]":"118.4","Cell RNA - SH-SY5Y [nTPM]":"61.7","Cell RNA - SiHa [nTPM]":"79.2","Cell RNA - SK-BR-3 [nTPM]":"77.7","Cell RNA - SK-MEL-30 [nTPM]":"33.9","Cell RNA - SuSa [nTPM]":"90.8","Cell RNA - T-47d [nTPM]":"30.1","Cell RNA - THP-1 [nTPM]":"152.9","Cell RNA - TIME [nTPM]":"53.5","Cell RNA - U-138 MG [nTPM]":"78.2","Cell RNA - U-2 OS [nTPM]":"119.6","Cell RNA - U-2197 [nTPM]":"61.7","Cell RNA - U-251 MG [nTPM]":"167.2","Cell RNA - U-266\/70 [nTPM]":"36.8","Cell RNA - U-266\/84 [nTPM]":"50.8","Cell RNA - U-698 [nTPM]":"134.5","Cell RNA - U-87 MG [nTPM]":"59.8","Cell RNA - U-937 [nTPM]":"84.5","Cell RNA - WM-115 [nTPM]":"97.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"6.5","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"5.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"4.3","Blood RNA - myeloid DC [nTPM]":"11.0","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"6.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"11.9","Blood RNA - T-reg [nTPM]":"6.3","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"5.8","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.4","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"10.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"7.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.4","Single Cell Type RNA - dendritic cells [nTPM]":"26.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"19.2","Single Cell Type RNA - Early spermatids [nTPM]":"32.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"8.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"22.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"15.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"29.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.2","Single Cell Type RNA - Late spermatids [nTPM]":"27.9","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"6.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"8.7","Single Cell Type RNA - Muller glia cells [nTPM]":"5.4","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"24.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.5","Single Cell Type RNA - Spermatocytes [nTPM]":"11.1","Single Cell Type RNA - Spermatogonia [nTPM]":"40.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"9.9","Single Cell Type RNA - Theca cells [nTPM]":"20.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.8","Single Cell Type RNA - Urothelial cells [nTPM]":"7.3"},{"Gene":"CXCR4","Gene synonym":["CD184","D2S201E","fusin","HM89","HSY3RR","LESTR","NPY3R","NPYR","NPYY3R"],"Ensembl":"ENSG00000121966","Gene description":"C-X-C motif chemokine receptor 4","Uniprot":["P61073"],"Chromosome":"2","Position":"136114349-136118149","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["G-protein coupled receptor","Host cell receptor for virus entry","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1175.1","lymphoid tissue":"549.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1446.9","dendritic cells":"1015.1","Langerhans cells":"486.2","Macrophages":"513.6","Plasma cells":"534.2","T-cells":"1436.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"580.8","JURKAT":"323.6","Karpas-707":"302.1","MOLT-4":"538.9","REH":"281.0","U-266\/70":"648.5","U-698":"677.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.41e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"51.8","Tissue RNA - adrenal gland [nTPM]":"184.5","Tissue RNA - amygdala [nTPM]":"11.8","Tissue RNA - appendix [nTPM]":"297.9","Tissue RNA - basal ganglia [nTPM]":"11.4","Tissue RNA - bone marrow [nTPM]":"1175.1","Tissue RNA - breast [nTPM]":"39.6","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"23.8","Tissue RNA - cervix [nTPM]":"36.1","Tissue RNA - choroid plexus [nTPM]":"20.1","Tissue RNA - colon [nTPM]":"33.2","Tissue RNA - duodenum [nTPM]":"12.6","Tissue RNA - endometrium 1 [nTPM]":"35.2","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"34.9","Tissue RNA - fallopian tube [nTPM]":"64.9","Tissue RNA - gallbladder [nTPM]":"84.5","Tissue RNA - heart muscle [nTPM]":"21.8","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"19.7","Tissue RNA - kidney [nTPM]":"29.0","Tissue RNA - liver [nTPM]":"52.4","Tissue RNA - lung [nTPM]":"95.5","Tissue RNA - lymph node [nTPM]":"383.8","Tissue RNA - medulla oblongata [nTPM]":"24.3","Tissue RNA - midbrain [nTPM]":"12.8","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"10.0","Tissue RNA - parathyroid gland [nTPM]":"12.3","Tissue RNA - pituitary gland [nTPM]":"32.6","Tissue RNA - placenta [nTPM]":"57.5","Tissue RNA - pons [nTPM]":"18.2","Tissue RNA - prostate [nTPM]":"34.1","Tissue RNA - rectum [nTPM]":"48.6","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"30.2","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"9.8","Tissue RNA - small intestine [nTPM]":"246.5","Tissue RNA - smooth muscle [nTPM]":"28.1","Tissue RNA - spinal cord [nTPM]":"16.7","Tissue RNA - spleen [nTPM]":"346.5","Tissue RNA - stomach 1 [nTPM]":"64.0","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"491.2","Tissue RNA - thyroid gland [nTPM]":"36.7","Tissue RNA - tongue [nTPM]":"12.0","Tissue RNA - tonsil [nTPM]":"549.3","Tissue RNA - urinary bladder [nTPM]":"99.3","Tissue RNA - vagina [nTPM]":"26.9","Tissue RNA - white matter [nTPM]":"32.3","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"9.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"580.8","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"29.6","Cell RNA - HEK 293 [nTPM]":"6.9","Cell RNA - HEL [nTPM]":"35.1","Cell RNA - HeLa [nTPM]":"84.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"81.5","Cell RNA - HMC-1 [nTPM]":"60.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"54.5","Cell RNA - JURKAT [nTPM]":"323.6","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"302.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"538.9","Cell RNA - NB-4 [nTPM]":"72.8","Cell RNA - NTERA-2 [nTPM]":"9.3","Cell RNA - OE19 [nTPM]":"45.4","Cell RNA - PC-3 [nTPM]":"2.9","Cell RNA - REH [nTPM]":"281.0","Cell RNA - RH-30 [nTPM]":"62.6","Cell RNA - RPMI-8226 [nTPM]":"102.5","Cell RNA - RPTEC TERT1 [nTPM]":"4.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"30.9","Cell RNA - SH-SY5Y [nTPM]":"26.1","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"156.7","Cell RNA - TIME [nTPM]":"8.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.0","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"648.5","Cell RNA - U-266\/84 [nTPM]":"116.7","Cell RNA - U-698 [nTPM]":"677.4","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"131.8","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"87.0","Blood RNA - classical monocyte [nTPM]":"28.5","Blood RNA - eosinophil [nTPM]":"117.8","Blood RNA - gdT-cell [nTPM]":"83.8","Blood RNA - intermediate monocyte [nTPM]":"15.6","Blood RNA - MAIT T-cell [nTPM]":"67.3","Blood RNA - memory B-cell [nTPM]":"115.6","Blood RNA - memory CD4 T-cell [nTPM]":"76.5","Blood RNA - memory CD8 T-cell [nTPM]":"79.6","Blood RNA - myeloid DC [nTPM]":"25.7","Blood RNA - naive B-cell [nTPM]":"166.2","Blood RNA - naive CD4 T-cell [nTPM]":"113.1","Blood RNA - naive CD8 T-cell [nTPM]":"109.5","Blood RNA - neutrophil [nTPM]":"143.3","Blood RNA - NK-cell [nTPM]":"17.2","Blood RNA - non-classical monocyte [nTPM]":"9.1","Blood RNA - plasmacytoid DC [nTPM]":"63.7","Blood RNA - T-reg [nTPM]":"76.1","Blood RNA - total PBMC [nTPM]":"51.9","Brain RNA - amygdala [nTPM]":"11.8","Brain RNA - basal ganglia [nTPM]":"11.4","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"23.8","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"19.7","Brain RNA - medulla oblongata [nTPM]":"24.3","Brain RNA - midbrain [nTPM]":"12.8","Brain RNA - pons [nTPM]":"18.2","Brain RNA - spinal cord [nTPM]":"16.7","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"32.3","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"42.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"1446.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"8.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"46.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"1015.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"5.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.9","Single Cell Type RNA - Endothelial cells [nTPM]":"67.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"67.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"28.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"52.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.0","Single Cell Type RNA - granulocytes [nTPM]":"12.6","Single Cell Type RNA - Granulosa cells [nTPM]":"9.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"9.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"159.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"270.0","Single Cell Type RNA - Langerhans cells [nTPM]":"486.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"513.6","Single Cell Type RNA - Melanocytes [nTPM]":"113.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"189.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"153.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"534.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"99.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"1436.5","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.8","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"CYBA","Gene synonym":["p22-PHOX"],"Ensembl":"ENSG00000051523","Gene description":"Cytochrome b-245 alpha chain","Uniprot":["P13498"],"Chromosome":"16","Position":"88643289-88651054","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"742.0","lymphoid tissue":"693.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"1632.1","Hofbauer cells":"2171.9","Kupffer cells":"1734.2","Macrophages":"1682.8","monocytes":"1688.5","NK-cells":"1805.4","Plasma cells":"1990.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"733.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"1058.3","RPMI-8226":"1631.2","THP-1":"1231.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009492"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009492":"AB_2090309"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"149.9","Tissue RNA - adrenal gland [nTPM]":"68.0","Tissue RNA - amygdala [nTPM]":"40.3","Tissue RNA - appendix [nTPM]":"344.4","Tissue RNA - basal ganglia [nTPM]":"41.8","Tissue RNA - bone marrow [nTPM]":"742.0","Tissue RNA - breast [nTPM]":"93.3","Tissue RNA - cerebellum [nTPM]":"46.0","Tissue RNA - cerebral cortex [nTPM]":"58.0","Tissue RNA - cervix [nTPM]":"81.9","Tissue RNA - choroid plexus [nTPM]":"62.4","Tissue RNA - colon [nTPM]":"200.9","Tissue RNA - duodenum [nTPM]":"196.6","Tissue RNA - endometrium 1 [nTPM]":"60.8","Tissue RNA - epididymis [nTPM]":"38.5","Tissue RNA - esophagus [nTPM]":"80.9","Tissue RNA - fallopian tube [nTPM]":"95.4","Tissue RNA - gallbladder [nTPM]":"122.5","Tissue RNA - heart muscle [nTPM]":"93.2","Tissue RNA - hippocampal formation [nTPM]":"38.6","Tissue RNA - hypothalamus [nTPM]":"55.0","Tissue RNA - kidney [nTPM]":"187.7","Tissue RNA - liver [nTPM]":"71.5","Tissue RNA - lung [nTPM]":"234.6","Tissue RNA - lymph node [nTPM]":"333.8","Tissue RNA - medulla oblongata [nTPM]":"73.8","Tissue RNA - midbrain [nTPM]":"49.3","Tissue RNA - ovary [nTPM]":"40.0","Tissue RNA - pancreas [nTPM]":"108.6","Tissue RNA - parathyroid gland [nTPM]":"13.4","Tissue RNA - pituitary gland [nTPM]":"40.6","Tissue RNA - placenta [nTPM]":"54.9","Tissue RNA - pons [nTPM]":"64.1","Tissue RNA - prostate [nTPM]":"75.2","Tissue RNA - rectum [nTPM]":"79.9","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"116.7","Tissue RNA - seminal vesicle [nTPM]":"26.6","Tissue RNA - skeletal muscle [nTPM]":"41.8","Tissue RNA - skin 1 [nTPM]":"39.4","Tissue RNA - small intestine [nTPM]":"245.3","Tissue RNA - smooth muscle [nTPM]":"51.3","Tissue RNA - spinal cord [nTPM]":"65.4","Tissue RNA - spleen [nTPM]":"693.1","Tissue RNA - stomach 1 [nTPM]":"236.0","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"62.4","Tissue RNA - thymus [nTPM]":"87.1","Tissue RNA - thyroid gland [nTPM]":"136.5","Tissue RNA - tongue [nTPM]":"19.9","Tissue RNA - tonsil [nTPM]":"192.8","Tissue RNA - urinary bladder [nTPM]":"144.6","Tissue RNA - vagina [nTPM]":"74.1","Tissue RNA - white matter [nTPM]":"92.2","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"663.0","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"1.5","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"329.5","Cell RNA - BJ [nTPM]":"155.7","Cell RNA - BJ hTERT+ [nTPM]":"77.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.1","Cell RNA - CACO-2 [nTPM]":"447.2","Cell RNA - CAPAN-2 [nTPM]":"819.6","Cell RNA - Daudi [nTPM]":"510.5","Cell RNA - EFO-21 [nTPM]":"420.7","Cell RNA - fHDF\/TERT166 [nTPM]":"56.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"250.5","Cell RNA - HAP1 [nTPM]":"21.4","Cell RNA - HBEC3-KT [nTPM]":"0.9","Cell RNA - HBF TERT88 [nTPM]":"5.8","Cell RNA - HDLM-2 [nTPM]":"146.1","Cell RNA - HEK 293 [nTPM]":"564.1","Cell RNA - HEL [nTPM]":"99.0","Cell RNA - HeLa [nTPM]":"217.7","Cell RNA - Hep G2 [nTPM]":"694.9","Cell RNA - HHSteC [nTPM]":"75.7","Cell RNA - HL-60 [nTPM]":"156.3","Cell RNA - HMC-1 [nTPM]":"397.6","Cell RNA - HSkMC [nTPM]":"80.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"23.9","Cell RNA - JURKAT [nTPM]":"103.6","Cell RNA - K-562 [nTPM]":"278.5","Cell RNA - Karpas-707 [nTPM]":"567.5","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"1058.3","Cell RNA - MOLT-4 [nTPM]":"147.9","Cell RNA - NB-4 [nTPM]":"822.3","Cell RNA - NTERA-2 [nTPM]":"106.2","Cell RNA - OE19 [nTPM]":"248.7","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"437.9","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"1631.2","Cell RNA - RPTEC TERT1 [nTPM]":"324.9","Cell RNA - RT4 [nTPM]":"490.9","Cell RNA - SCLC-21H [nTPM]":"84.2","Cell RNA - SH-SY5Y [nTPM]":"76.5","Cell RNA - SiHa [nTPM]":"482.7","Cell RNA - SK-BR-3 [nTPM]":"78.8","Cell RNA - SK-MEL-30 [nTPM]":"138.5","Cell RNA - SuSa [nTPM]":"60.8","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"1231.3","Cell RNA - TIME [nTPM]":"129.8","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"362.9","Cell RNA - U-266\/84 [nTPM]":"459.9","Cell RNA - U-698 [nTPM]":"543.6","Cell RNA - U-87 MG [nTPM]":"195.5","Cell RNA - U-937 [nTPM]":"464.9","Cell RNA - WM-115 [nTPM]":"53.4","Blood RNA - basophil [nTPM]":"120.2","Blood RNA - classical monocyte [nTPM]":"103.8","Blood RNA - eosinophil [nTPM]":"733.7","Blood RNA - gdT-cell [nTPM]":"76.7","Blood RNA - intermediate monocyte [nTPM]":"150.1","Blood RNA - MAIT T-cell [nTPM]":"55.8","Blood RNA - memory B-cell [nTPM]":"109.8","Blood RNA - memory CD4 T-cell [nTPM]":"36.7","Blood RNA - memory CD8 T-cell [nTPM]":"70.4","Blood RNA - myeloid DC [nTPM]":"107.0","Blood RNA - naive B-cell [nTPM]":"110.7","Blood RNA - naive CD4 T-cell [nTPM]":"28.9","Blood RNA - naive CD8 T-cell [nTPM]":"36.7","Blood RNA - neutrophil [nTPM]":"192.3","Blood RNA - NK-cell [nTPM]":"36.4","Blood RNA - non-classical monocyte [nTPM]":"143.3","Blood RNA - plasmacytoid DC [nTPM]":"196.3","Blood RNA - T-reg [nTPM]":"41.2","Blood RNA - total PBMC [nTPM]":"47.3","Brain RNA - amygdala [nTPM]":"40.3","Brain RNA - basal ganglia [nTPM]":"41.8","Brain RNA - cerebellum [nTPM]":"46.0","Brain RNA - cerebral cortex [nTPM]":"58.0","Brain RNA - hippocampal formation [nTPM]":"38.6","Brain RNA - hypothalamus [nTPM]":"55.0","Brain RNA - medulla oblongata [nTPM]":"73.8","Brain RNA - midbrain [nTPM]":"49.3","Brain RNA - pons [nTPM]":"64.1","Brain RNA - spinal cord [nTPM]":"65.4","Brain RNA - thalamus [nTPM]":"62.4","Brain RNA - white matter [nTPM]":"92.2","Single Cell Type RNA - Adipocytes [nTPM]":"157.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1290.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"119.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"233.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"420.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"53.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"131.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"133.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"368.9","Single Cell Type RNA - Club cells [nTPM]":"487.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"285.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"45.3","Single Cell Type RNA - dendritic cells [nTPM]":"1632.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"807.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"127.2","Single Cell Type RNA - Ductal cells [nTPM]":"636.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"219.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"137.5","Single Cell Type RNA - Endothelial cells [nTPM]":"137.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"230.5","Single Cell Type RNA - Erythroid cells [nTPM]":"162.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"155.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"299.0","Single Cell Type RNA - Fibroblasts [nTPM]":"184.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"285.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"312.5","Single Cell Type RNA - granulocytes [nTPM]":"279.0","Single Cell Type RNA - Granulosa cells [nTPM]":"104.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"317.0","Single Cell Type RNA - Hepatocytes [nTPM]":"23.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"2171.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"540.3","Single Cell Type RNA - Ionocytes [nTPM]":"233.9","Single Cell Type RNA - Kupffer cells [nTPM]":"1734.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1370.8","Single Cell Type RNA - Late spermatids [nTPM]":"14.0","Single Cell Type RNA - Leydig cells [nTPM]":"50.1","Single Cell Type RNA - Macrophages [nTPM]":"1682.8","Single Cell Type RNA - Melanocytes [nTPM]":"1152.6","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"1688.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.6","Single Cell Type RNA - NK-cells [nTPM]":"1805.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"682.8","Single Cell Type RNA - Paneth cells [nTPM]":"1045.8","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"1990.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"191.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"390.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1057.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"529.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"164.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"85.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"118.2","Single Cell Type RNA - T-cells [nTPM]":"838.6","Single Cell Type RNA - Theca cells [nTPM]":"20.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"805.2","Single Cell Type RNA - Urothelial cells [nTPM]":"436.9"},{"Gene":"CYBB","Gene synonym":["CGD","GP91-PHOX","NOX2"],"Ensembl":"ENSG00000165168","Gene description":"Cytochrome b-245 beta chain","Uniprot":["P04839"],"Chromosome":"X","Position":"37780059-37813461","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Ion transport","Transport"],"Molecular function":["Ion channel","Oxidoreductase","Voltage-gated channel"],"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"160.9","lymphoid tissue":"158.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"157.2","Kupffer cells":"456.0","Macrophages":"469.3","monocytes":"396.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"276.3","intermediate monocyte":"261.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"90.9","granulocytes":"110.5","monocytes":"276.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Daudi":"52.8","NB-4":"64.2","REH":"54.6","RPMI-8226":"210.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051227"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051227":"AB_2681395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.5","Tissue RNA - adrenal gland [nTPM]":"28.4","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"158.9","Tissue RNA - basal ganglia [nTPM]":"5.3","Tissue RNA - bone marrow [nTPM]":"160.9","Tissue RNA - breast [nTPM]":"15.2","Tissue RNA - cerebellum [nTPM]":"6.5","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"12.3","Tissue RNA - choroid plexus [nTPM]":"12.4","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"19.3","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"9.9","Tissue RNA - gallbladder [nTPM]":"26.2","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"27.5","Tissue RNA - lung [nTPM]":"91.5","Tissue RNA - lymph node [nTPM]":"97.1","Tissue RNA - medulla oblongata [nTPM]":"15.1","Tissue RNA - midbrain [nTPM]":"9.6","Tissue RNA - ovary [nTPM]":"6.9","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"4.4","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"54.6","Tissue RNA - pons [nTPM]":"13.3","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"30.6","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"7.0","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"22.3","Tissue RNA - smooth muscle [nTPM]":"55.5","Tissue RNA - spinal cord [nTPM]":"12.5","Tissue RNA - spleen [nTPM]":"89.0","Tissue RNA - stomach 1 [nTPM]":"17.2","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"11.1","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"5.5","Tissue RNA - tonsil [nTPM]":"73.2","Tissue RNA - urinary bladder [nTPM]":"46.8","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"24.0","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.2","Cell RNA - Daudi [nTPM]":"52.8","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"3.6","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.6","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"64.2","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"54.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"210.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"20.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"1.6","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"8.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"276.3","Blood RNA - eosinophil [nTPM]":"110.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"261.6","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"39.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"62.8","Blood RNA - naive B-cell [nTPM]":"32.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"237.1","Blood RNA - plasmacytoid DC [nTPM]":"90.9","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"162.5","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"5.3","Brain RNA - cerebellum [nTPM]":"6.5","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"15.1","Brain RNA - midbrain [nTPM]":"9.6","Brain RNA - pons [nTPM]":"13.3","Brain RNA - spinal cord [nTPM]":"12.5","Brain RNA - thalamus [nTPM]":"11.1","Brain RNA - white matter [nTPM]":"24.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"99.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"82.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"157.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"456.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"469.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"76.8","Single Cell Type RNA - monocytes [nTPM]":"396.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"DCLRE1C","Gene synonym":["A-SCID","ARTEMIS","FLJ11360","SCIDA","SNM1C"],"Ensembl":"ENSG00000152457","Gene description":"DNA cross-link repair 1C","Uniprot":["Q96SD1"],"Chromosome":"10","Position":"14897359-14954432","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","DNA damage","DNA recombination","DNA repair","Immunity"],"Molecular function":["Endonuclease","Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"62.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069295"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA069295":"AB_2686112"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.30e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.98e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.03e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"3.3","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"8.0","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"14.0","Tissue RNA - breast [nTPM]":"6.1","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"4.5","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"3.5","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"14.1","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"3.8","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"4.4","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"6.9","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"10.4","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"16.2","Cell RNA - A549 [nTPM]":"7.8","Cell RNA - AF22 [nTPM]":"6.9","Cell RNA - AN3-CA [nTPM]":"13.8","Cell RNA - ASC diff [nTPM]":"6.4","Cell RNA - ASC TERT1 [nTPM]":"8.2","Cell RNA - BEWO [nTPM]":"6.6","Cell RNA - BJ [nTPM]":"9.7","Cell RNA - BJ hTERT+ [nTPM]":"5.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.5","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"13.4","Cell RNA - Daudi [nTPM]":"21.7","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"7.6","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"7.6","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"10.9","Cell RNA - HDLM-2 [nTPM]":"13.4","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"6.0","Cell RNA - HHSteC [nTPM]":"5.1","Cell RNA - HL-60 [nTPM]":"10.0","Cell RNA - HMC-1 [nTPM]":"18.4","Cell RNA - HSkMC [nTPM]":"6.6","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.7","Cell RNA - hTERT-HME1 [nTPM]":"5.3","Cell RNA - hTERT-RPE1 [nTPM]":"8.2","Cell RNA - HUVEC TERT2 [nTPM]":"7.4","Cell RNA - JURKAT [nTPM]":"13.9","Cell RNA - K-562 [nTPM]":"10.5","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"8.6","Cell RNA - MCF7 [nTPM]":"7.4","Cell RNA - MOLT-4 [nTPM]":"14.9","Cell RNA - NB-4 [nTPM]":"9.9","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"14.4","Cell RNA - PC-3 [nTPM]":"3.5","Cell RNA - REH [nTPM]":"17.2","Cell RNA - RH-30 [nTPM]":"9.2","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"6.5","Cell RNA - RT4 [nTPM]":"6.0","Cell RNA - SCLC-21H [nTPM]":"3.6","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"10.7","Cell RNA - SK-BR-3 [nTPM]":"10.2","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"5.3","Cell RNA - T-47d [nTPM]":"12.8","Cell RNA - THP-1 [nTPM]":"18.5","Cell RNA - TIME [nTPM]":"6.0","Cell RNA - U-138 MG [nTPM]":"8.3","Cell RNA - U-2 OS [nTPM]":"11.6","Cell RNA - U-2197 [nTPM]":"17.1","Cell RNA - U-251 MG [nTPM]":"10.8","Cell RNA - U-266\/70 [nTPM]":"9.9","Cell RNA - U-266\/84 [nTPM]":"19.1","Cell RNA - U-698 [nTPM]":"21.5","Cell RNA - U-87 MG [nTPM]":"8.1","Cell RNA - U-937 [nTPM]":"10.5","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"27.4","Blood RNA - classical monocyte [nTPM]":"13.9","Blood RNA - eosinophil [nTPM]":"20.0","Blood RNA - gdT-cell [nTPM]":"12.1","Blood RNA - intermediate monocyte [nTPM]":"18.9","Blood RNA - MAIT T-cell [nTPM]":"14.5","Blood RNA - memory B-cell [nTPM]":"25.1","Blood RNA - memory CD4 T-cell [nTPM]":"14.1","Blood RNA - memory CD8 T-cell [nTPM]":"15.0","Blood RNA - myeloid DC [nTPM]":"20.9","Blood RNA - naive B-cell [nTPM]":"28.1","Blood RNA - naive CD4 T-cell [nTPM]":"12.2","Blood RNA - naive CD8 T-cell [nTPM]":"13.2","Blood RNA - neutrophil [nTPM]":"13.2","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"17.5","Blood RNA - plasmacytoid DC [nTPM]":"22.4","Blood RNA - T-reg [nTPM]":"11.9","Blood RNA - total PBMC [nTPM]":"8.9","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.9","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"27.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"24.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"26.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"62.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"26.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"8.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"22.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.9","Single Cell Type RNA - Fibroblasts [nTPM]":"10.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.2","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"13.3","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.9","Single Cell Type RNA - Paneth cells [nTPM]":"15.5","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"13.9","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"14.8","Single Cell Type RNA - Theca cells [nTPM]":"12.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.6","Single Cell Type RNA - Urothelial cells [nTPM]":"41.4"},{"Gene":"DNMT3B","Gene synonym":[],"Ensembl":"ENSG00000088305","Gene description":"DNA methyltransferase 3 beta","Uniprot":["Q9UBC3"],"Chromosome":"20","Position":"32762385-32809356","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Activator","DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"5.3","Extravillous trophoblasts":"5.2","Horizontal cells":"5.0","Inhibitory neurons":"6.8","Sertoli cells":"6.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"25","RNA cancer specific FPKM":{"testis cancer":"111.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"245.7","CACO-2":"95.8","HEL":"100.7","K-562":"98.6","NTERA-2":"333.9","SuSa":"174.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001595","HPA001803","CAB069896"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB069896":"AB_2094115","HPA001595":"AB_1847814","HPA001803":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.0","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"5.3","Cell RNA - AF22 [nTPM]":"27.0","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"245.7","Cell RNA - BJ [nTPM]":"3.5","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.8","Cell RNA - CACO-2 [nTPM]":"95.8","Cell RNA - CAPAN-2 [nTPM]":"4.3","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"9.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"17.6","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"14.0","Cell RNA - HEL [nTPM]":"100.7","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"18.5","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"4.6","Cell RNA - HMC-1 [nTPM]":"9.7","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.5","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"6.6","Cell RNA - JURKAT [nTPM]":"6.2","Cell RNA - K-562 [nTPM]":"98.6","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"1.4","Cell RNA - MCF7 [nTPM]":"15.7","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"86.1","Cell RNA - NTERA-2 [nTPM]":"333.9","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"15.4","Cell RNA - RH-30 [nTPM]":"4.5","Cell RNA - RPMI-8226 [nTPM]":"2.3","Cell RNA - RPTEC TERT1 [nTPM]":"9.1","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"5.7","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"8.5","Cell RNA - SK-MEL-30 [nTPM]":"2.5","Cell RNA - SuSa [nTPM]":"174.4","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"2.8","Cell RNA - U-251 MG [nTPM]":"2.6","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"2.8","Cell RNA - U-698 [nTPM]":"3.8","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"27.4","Cell RNA - WM-115 [nTPM]":"2.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"DOCK2","Gene synonym":["KIAA0209"],"Ensembl":"ENSG00000134516","Gene description":"Dedicator of cytokinesis 2","Uniprot":["Q92608"],"Chromosome":"5","Position":"169637268-170083382","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"61.6","lung":"16.4","lymphoid tissue":"51.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"53.3","dendritic cells":"78.1","Kupffer cells":"93.2","Macrophages":"78.0","Microglial cells":"173.3","monocytes":"72.5","T-cells":"50.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"123.4","HDLM-2":"172.7","HL-60":"132.7","HMC-1":"135.8","MOLT-4":"94.5","U-698":"112.4","U-937":"85.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036469"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA036469":"AB_2675140"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"34.4","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"61.6","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"5.0","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"5.5","Tissue RNA - lung [nTPM]":"16.4","Tissue RNA - lymph node [nTPM]":"42.5","Tissue RNA - medulla oblongata [nTPM]":"6.4","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"7.3","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"2.6","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"36.5","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"6.3","Tissue RNA - thymus [nTPM]":"51.4","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"46.9","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"8.4","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.3","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"123.4","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"13.0","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"19.5","Cell RNA - HDLM-2 [nTPM]":"172.7","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"71.0","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"132.7","Cell RNA - HMC-1 [nTPM]":"135.8","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"65.1","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"60.3","Cell RNA - LHCN-M2 [nTPM]":"8.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"94.5","Cell RNA - NB-4 [nTPM]":"27.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"59.9","Cell RNA - RH-30 [nTPM]":"4.8","Cell RNA - RPMI-8226 [nTPM]":"49.3","Cell RNA - RPTEC TERT1 [nTPM]":"3.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"64.8","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"4.1","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"18.6","Cell RNA - U-266\/84 [nTPM]":"40.9","Cell RNA - U-698 [nTPM]":"112.4","Cell RNA - U-87 MG [nTPM]":"7.3","Cell RNA - U-937 [nTPM]":"85.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"19.7","Blood RNA - classical monocyte [nTPM]":"28.6","Blood RNA - eosinophil [nTPM]":"22.0","Blood RNA - gdT-cell [nTPM]":"12.3","Blood RNA - intermediate monocyte [nTPM]":"48.6","Blood RNA - MAIT T-cell [nTPM]":"12.6","Blood RNA - memory B-cell [nTPM]":"13.2","Blood RNA - memory CD4 T-cell [nTPM]":"11.3","Blood RNA - memory CD8 T-cell [nTPM]":"12.6","Blood RNA - myeloid DC [nTPM]":"29.8","Blood RNA - naive B-cell [nTPM]":"9.7","Blood RNA - naive CD4 T-cell [nTPM]":"7.8","Blood RNA - naive CD8 T-cell [nTPM]":"9.5","Blood RNA - neutrophil [nTPM]":"29.4","Blood RNA - NK-cell [nTPM]":"13.5","Blood RNA - non-classical monocyte [nTPM]":"72.1","Blood RNA - plasmacytoid DC [nTPM]":"10.9","Blood RNA - T-reg [nTPM]":"11.7","Blood RNA - total PBMC [nTPM]":"24.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"6.4","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"6.3","Brain RNA - white matter [nTPM]":"8.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"53.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"78.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"15.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"33.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"93.2","Single Cell Type RNA - Langerhans cells [nTPM]":"31.1","Single Cell Type RNA - Late spermatids [nTPM]":"5.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"78.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"173.3","Single Cell Type RNA - monocytes [nTPM]":"72.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"39.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"50.8","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"DOCK8","Gene synonym":["FLJ00026","FLJ00152","FLJ00346","ZIR8"],"Ensembl":"ENSG00000107099","Gene description":"Dedicator of cytokinesis 8","Uniprot":["Q8NF50"],"Chromosome":"9","Position":"214854-465259","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":["Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"45.0","lymphoid tissue":"64.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"506.8","monocytes":"134.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"173.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"53.0","granulocytes":"173.6","monocytes":"84.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"52.9","HL-60":"53.3","MOLT-4":"50.1","NB-4":"83.7","REH":"61.9","RT4":"54.3","THP-1":"158.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003218","HPA073349"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Centrosome"],"Subcellular additional location":["Nucleoplasm","Mitochondria","Cytosol"],"Antibody RRID":{"HPA003218":"AB_1078695","HPA073349":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.89e-6"},"Tissue RNA - adipose tissue [nTPM]":"11.0","Tissue RNA - adrenal gland [nTPM]":"13.3","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"35.7","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"42.2","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"45.0","Tissue RNA - colon [nTPM]":"7.3","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"14.6","Tissue RNA - heart muscle [nTPM]":"2.0","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"5.9","Tissue RNA - kidney [nTPM]":"16.5","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"19.7","Tissue RNA - lymph node [nTPM]":"51.1","Tissue RNA - medulla oblongata [nTPM]":"8.8","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"2.0","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"15.3","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"7.3","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"15.4","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"45.6","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"7.5","Tissue RNA - thalamus [nTPM]":"8.8","Tissue RNA - thymus [nTPM]":"64.8","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"49.6","Tissue RNA - urinary bladder [nTPM]":"14.8","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"10.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.6","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"52.9","Cell RNA - EFO-21 [nTPM]":"3.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"2.3","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"18.2","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"53.3","Cell RNA - HMC-1 [nTPM]":"7.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"9.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"11.8","Cell RNA - Karpas-707 [nTPM]":"25.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"50.1","Cell RNA - NB-4 [nTPM]":"83.7","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"61.9","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"21.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"54.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"3.6","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"158.0","Cell RNA - TIME [nTPM]":"10.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"10.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"33.3","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"65.1","Blood RNA - classical monocyte [nTPM]":"56.9","Blood RNA - eosinophil [nTPM]":"73.5","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"52.0","Blood RNA - MAIT T-cell [nTPM]":"10.2","Blood RNA - memory B-cell [nTPM]":"25.2","Blood RNA - memory CD4 T-cell [nTPM]":"15.7","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"53.0","Blood RNA - naive B-cell [nTPM]":"23.2","Blood RNA - naive CD4 T-cell [nTPM]":"11.3","Blood RNA - naive CD8 T-cell [nTPM]":"11.1","Blood RNA - neutrophil [nTPM]":"173.6","Blood RNA - NK-cell [nTPM]":"24.1","Blood RNA - non-classical monocyte [nTPM]":"84.2","Blood RNA - plasmacytoid DC [nTPM]":"13.8","Blood RNA - T-reg [nTPM]":"15.6","Blood RNA - total PBMC [nTPM]":"22.6","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"5.9","Brain RNA - medulla oblongata [nTPM]":"8.8","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"8.8","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"112.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"4.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"77.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"70.9","Single Cell Type RNA - dendritic cells [nTPM]":"101.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"33.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"9.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"35.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"12.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"115.0","Single Cell Type RNA - Langerhans cells [nTPM]":"49.4","Single Cell Type RNA - Late spermatids [nTPM]":"14.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"107.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"506.8","Single Cell Type RNA - monocytes [nTPM]":"134.3","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"74.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"24.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"94.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"22.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.7","Single Cell Type RNA - T-cells [nTPM]":"111.6","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"ELANE","Gene synonym":["ELA2","HLE","HNE","NE"],"Ensembl":"ENSG00000197561","Gene description":"Elastase, neutrophil expressed","Uniprot":["P08246"],"Chromosome":"19","Position":"851014-856247","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"91","RNA tissue specific nTPM":{"bone marrow":"3894.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"8.7","Fibroblasts":"16.2","Langerhans cells":"11.1","Leydig cells":"6.2","Melanocytes":"7.2","Suprabasal keratinocytes":"7.4"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"pancreatic cancer":"3.5","stomach cancer":"3.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"classical monocyte":"4.0","neutrophil":"12.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"12.1","monocytes":"4.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"91","RNA cell line specific nTPM":{"THP-1":"3105.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015409","HPA066836","HPA073774"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015409":"AB_831596","HPA066836":"AB_2685733","HPA073774":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"3894.9","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"4.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"19.4","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"2.9","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"5.4","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"42.6","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"6.3","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"2.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.3","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3105.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"34.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"12.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"27.2","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"16.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.4","Single Cell Type RNA - Langerhans cells [nTPM]":"11.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FAS","Gene synonym":["APO-1","APT1","CD95","FAS1","TNFRSF6"],"Ensembl":"ENSG00000026103","Gene description":"Fas cell surface death receptor","Uniprot":["P25445"],"Chromosome":"10","Position":"88990531-89017059","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Calmodulin-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"109.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"114.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"114.7","T-cells":"96.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"83.4","Karpas-707":"109.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027444"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":11900000,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA027444":"AB_10601378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.1","Tissue RNA - adrenal gland [nTPM]":"26.3","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"20.8","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"12.7","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"16.4","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"14.8","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"23.3","Tissue RNA - lung [nTPM]":"21.7","Tissue RNA - lymph node [nTPM]":"18.9","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"20.1","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"23.3","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"14.4","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"2.6","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"12.9","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"22.7","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"13.9","Cell RNA - ASC diff [nTPM]":"37.0","Cell RNA - ASC TERT1 [nTPM]":"51.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"51.8","Cell RNA - BJ hTERT+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"23.4","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"19.0","Cell RNA - fHDF\/TERT166 [nTPM]":"52.1","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"44.8","Cell RNA - HBF TERT88 [nTPM]":"3.2","Cell RNA - HDLM-2 [nTPM]":"83.4","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"14.7","Cell RNA - HHSteC [nTPM]":"31.6","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"69.2","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.4","Cell RNA - hTERT-HME1 [nTPM]":"66.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.7","Cell RNA - JURKAT [nTPM]":"17.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"109.0","Cell RNA - LHCN-M2 [nTPM]":"44.0","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"5.0","Cell RNA - RPTEC TERT1 [nTPM]":"60.7","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"7.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"9.5","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"9.0","Cell RNA - U-2197 [nTPM]":"15.2","Cell RNA - U-251 MG [nTPM]":"12.3","Cell RNA - U-266\/70 [nTPM]":"45.3","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"11.8","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"43.1","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"30.9","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"27.6","Blood RNA - memory CD8 T-cell [nTPM]":"19.6","Blood RNA - myeloid DC [nTPM]":"11.5","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.0","Blood RNA - neutrophil [nTPM]":"114.7","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"22.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"96.2","Blood RNA - total PBMC [nTPM]":"12.8","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.1","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"45.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"109.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"27.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"35.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"19.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"31.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"17.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"8.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"32.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.1","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"48.4","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.4","Single Cell Type RNA - Urothelial cells [nTPM]":"30.0"},{"Gene":"FASLG","Gene synonym":["APT1LG1","CD178","FasL","TNFSF6"],"Ensembl":"ENSG00000117560","Gene description":"Fas ligand","Uniprot":["P48023"],"Chromosome":"1","Position":"172659103-172666876","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Cytokine","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"5.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"dendritic cells":"43.4","NK-cells":"79.3","T-cells":"28.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"58.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"41.5","T-cells":"58.1"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054959"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":73600,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA054959":"AB_2682650"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.59e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.8","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"5.5","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"58.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"35.5","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"11.5","Blood RNA - memory CD8 T-cell [nTPM]":"31.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"25.0","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"41.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"14.9","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"43.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"79.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"28.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"FCGR3A","Gene synonym":["CD16","CD16a","FCG3","FCGR3"],"Ensembl":"ENSG00000203747","Gene description":"Fc fragment of IgG receptor IIIa","Uniprot":["P08637"],"Chromosome":"1","Position":"161541759-161550737","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["IgG-binding protein","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"206.3","lymphoid tissue":"306.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"333.4","Hofbauer cells":"193.1","Kupffer cells":"807.9","Macrophages":"300.0","NK-cells":"579.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"intermediate monocyte":"1763.5","neutrophil":"1169.8","non-classical monocyte":"3948.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"1169.8","monocytes":"3948.7"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032435","HPA055431"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032435":"AB_626925","HPA055431":"AB_2682815"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"52.9","Tissue RNA - adrenal gland [nTPM]":"41.9","Tissue RNA - amygdala [nTPM]":"18.4","Tissue RNA - appendix [nTPM]":"99.8","Tissue RNA - basal ganglia [nTPM]":"20.4","Tissue RNA - bone marrow [nTPM]":"27.3","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"19.3","Tissue RNA - cerebral cortex [nTPM]":"27.2","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"26.5","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"5.9","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"9.1","Tissue RNA - gallbladder [nTPM]":"24.5","Tissue RNA - heart muscle [nTPM]":"22.3","Tissue RNA - hippocampal formation [nTPM]":"16.9","Tissue RNA - hypothalamus [nTPM]":"22.0","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"111.5","Tissue RNA - lung [nTPM]":"206.3","Tissue RNA - lymph node [nTPM]":"37.1","Tissue RNA - medulla oblongata [nTPM]":"37.7","Tissue RNA - midbrain [nTPM]":"27.9","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"13.6","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"71.0","Tissue RNA - pons [nTPM]":"30.6","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"12.6","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"14.7","Tissue RNA - seminal vesicle [nTPM]":"7.6","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"68.4","Tissue RNA - spinal cord [nTPM]":"31.7","Tissue RNA - spleen [nTPM]":"306.8","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"28.8","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"32.5","Tissue RNA - vagina [nTPM]":"3.5","Tissue RNA - white matter [nTPM]":"39.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"6.5","Blood RNA - classical monocyte [nTPM]":"26.2","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"513.6","Blood RNA - intermediate monocyte [nTPM]":"1763.5","Blood RNA - MAIT T-cell [nTPM]":"4.9","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"205.9","Blood RNA - myeloid DC [nTPM]":"175.8","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"184.0","Blood RNA - neutrophil [nTPM]":"1169.8","Blood RNA - NK-cell [nTPM]":"136.2","Blood RNA - non-classical monocyte [nTPM]":"3948.7","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"734.1","Brain RNA - amygdala [nTPM]":"18.4","Brain RNA - basal ganglia [nTPM]":"20.4","Brain RNA - cerebellum [nTPM]":"19.3","Brain RNA - cerebral cortex [nTPM]":"27.2","Brain RNA - hippocampal formation [nTPM]":"16.9","Brain RNA - hypothalamus [nTPM]":"22.0","Brain RNA - medulla oblongata [nTPM]":"37.7","Brain RNA - midbrain [nTPM]":"27.9","Brain RNA - pons [nTPM]":"30.6","Brain RNA - spinal cord [nTPM]":"31.7","Brain RNA - thalamus [nTPM]":"28.8","Brain RNA - white matter [nTPM]":"39.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"6.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"333.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"18.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"18.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.6","Single Cell Type RNA - Hepatocytes [nTPM]":"5.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"193.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"807.9","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"300.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"77.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"579.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"88.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"FERMT3","Gene synonym":["KIND3","MGC10966","MIG-2","MIG2B","UNC112C","URP2"],"Ensembl":"ENSG00000149781","Gene description":"Fermitin family member 3","Uniprot":["Q86UX7"],"Chromosome":"11","Position":"64206678-64223891","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"180.6","lymphoid tissue":"130.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"118.3","granulocytes":"96.4","Hofbauer cells":"193.1","Kupffer cells":"95.8","Langerhans cells":"88.0","Macrophages":"232.9","monocytes":"142.9","NK-cells":"93.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"306.9","HL-60":"135.9","HMC-1":"314.2","Karpas-707":"127.6","MOLT-4":"121.8","NB-4":"174.1","U-937":"138.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065231"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA065231":"AB_2685439"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.1","Tissue RNA - adrenal gland [nTPM]":"14.5","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"63.3","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"180.6","Tissue RNA - breast [nTPM]":"13.0","Tissue RNA - cerebellum [nTPM]":"11.2","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"17.3","Tissue RNA - duodenum [nTPM]":"22.0","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"13.6","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"12.0","Tissue RNA - hippocampal formation [nTPM]":"9.8","Tissue RNA - hypothalamus [nTPM]":"11.6","Tissue RNA - kidney [nTPM]":"11.1","Tissue RNA - liver [nTPM]":"12.5","Tissue RNA - lung [nTPM]":"46.2","Tissue RNA - lymph node [nTPM]":"89.2","Tissue RNA - medulla oblongata [nTPM]":"17.9","Tissue RNA - midbrain [nTPM]":"12.2","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"7.0","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"15.0","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"4.4","Tissue RNA - skeletal muscle [nTPM]":"6.0","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"34.1","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"13.3","Tissue RNA - spleen [nTPM]":"130.1","Tissue RNA - stomach 1 [nTPM]":"29.6","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"17.1","Tissue RNA - thymus [nTPM]":"48.7","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"41.8","Tissue RNA - urinary bladder [nTPM]":"19.8","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"15.3","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.3","Cell RNA - ASC TERT1 [nTPM]":"0.8","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"32.6","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"6.3","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"2.4","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"83.9","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"306.9","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"10.8","Cell RNA - HL-60 [nTPM]":"135.9","Cell RNA - HMC-1 [nTPM]":"314.2","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"81.2","Cell RNA - JURKAT [nTPM]":"77.0","Cell RNA - K-562 [nTPM]":"7.3","Cell RNA - Karpas-707 [nTPM]":"127.6","Cell RNA - LHCN-M2 [nTPM]":"8.6","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"121.8","Cell RNA - NB-4 [nTPM]":"174.1","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"72.4","Cell RNA - RH-30 [nTPM]":"8.8","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"4.5","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"92.6","Cell RNA - TIME [nTPM]":"7.8","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"2.5","Cell RNA - U-2197 [nTPM]":"1.9","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"59.4","Cell RNA - U-87 MG [nTPM]":"19.5","Cell RNA - U-937 [nTPM]":"138.9","Cell RNA - WM-115 [nTPM]":"86.6","Blood RNA - basophil [nTPM]":"204.1","Blood RNA - classical monocyte [nTPM]":"207.0","Blood RNA - eosinophil [nTPM]":"236.5","Blood RNA - gdT-cell [nTPM]":"120.0","Blood RNA - intermediate monocyte [nTPM]":"192.6","Blood RNA - MAIT T-cell [nTPM]":"114.9","Blood RNA - memory B-cell [nTPM]":"54.5","Blood RNA - memory CD4 T-cell [nTPM]":"94.1","Blood RNA - memory CD8 T-cell [nTPM]":"112.0","Blood RNA - myeloid DC [nTPM]":"162.0","Blood RNA - naive B-cell [nTPM]":"53.1","Blood RNA - naive CD4 T-cell [nTPM]":"60.9","Blood RNA - naive CD8 T-cell [nTPM]":"80.6","Blood RNA - neutrophil [nTPM]":"184.6","Blood RNA - NK-cell [nTPM]":"102.4","Blood RNA - non-classical monocyte [nTPM]":"151.2","Blood RNA - plasmacytoid DC [nTPM]":"195.7","Blood RNA - T-reg [nTPM]":"120.9","Blood RNA - total PBMC [nTPM]":"292.6","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"11.2","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"9.8","Brain RNA - hypothalamus [nTPM]":"11.6","Brain RNA - medulla oblongata [nTPM]":"17.9","Brain RNA - midbrain [nTPM]":"12.2","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"13.3","Brain RNA - thalamus [nTPM]":"17.1","Brain RNA - white matter [nTPM]":"15.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"52.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"118.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"62.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.3","Single Cell Type RNA - granulocytes [nTPM]":"96.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"193.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"95.8","Single Cell Type RNA - Langerhans cells [nTPM]":"88.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"232.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"142.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"93.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.3","Single Cell Type RNA - Paneth cells [nTPM]":"10.9","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"35.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"78.5","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"FOXN1","Gene synonym":["FKHL20","RONU","WHN"],"Ensembl":"ENSG00000109101","Gene description":"Forkhead box N1","Uniprot":["O15353"],"Chromosome":"17","Position":"28506243-28538900","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"18.4","lymphoid tissue":"10.7","skin 1":"41.1","vagina":"10.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"4.0","Prostatic glandular cells":"5.9","Squamous epithelial cells":"15.9","Suprabasal keratinocytes":"12.4","Urothelial cells":"15.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"7.0","head and neck cancer":"8.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HaCaT":"10.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-6"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.00e-4"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"4.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"18.4","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"41.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"10.7","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"5.6","Tissue RNA - urinary bladder [nTPM]":"0.8","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"10.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"15.4"},{"Gene":"FOXP3","Gene synonym":["AIID","DIETER","IPEX","JM2","PIDX","SCURFIN","XPID"],"Ensembl":"ENSG00000049768","Gene description":"Forkhead box P3","Uniprot":["Q9BZS1"],"Chromosome":"X","Position":"49250438-49270477","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Diabetes mellitus","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"7.2","lymphoid tissue":"7.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"1.3","Hepatocytes":"1.4","Horizontal cells":"3.3","Melanocytes":"1.8","T-cells":"5.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"T-reg":"53.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"394","RNA blood lineage specific nTPM":{"T-cells":"53.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"2.9","MCF7":"5.2","SiHa":"4.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026301","HPA045943"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB026301":null,"HPA045943":"AB_2679508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.91e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.90e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"7.4","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"2.3","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"7.2","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"2.9","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"4.7","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"2.0","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"0.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"53.3","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"G6PC3","Gene synonym":["UGRP"],"Ensembl":"ENSG00000141349","Gene description":"Glucose-6-phosphatase catalytic subunit 3","Uniprot":["Q9BUM1"],"Chromosome":"17","Position":"44070735-44076344","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Gluconeogenesis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067052"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA067052":"AB_2685771"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-2"},"Tissue RNA - adipose tissue [nTPM]":"56.7","Tissue RNA - adrenal gland [nTPM]":"97.2","Tissue RNA - amygdala [nTPM]":"64.8","Tissue RNA - appendix [nTPM]":"22.5","Tissue RNA - basal ganglia [nTPM]":"67.8","Tissue RNA - bone marrow [nTPM]":"16.0","Tissue RNA - breast [nTPM]":"55.6","Tissue RNA - cerebellum [nTPM]":"70.5","Tissue RNA - cerebral cortex [nTPM]":"79.3","Tissue RNA - cervix [nTPM]":"47.6","Tissue RNA - choroid plexus [nTPM]":"88.8","Tissue RNA - colon [nTPM]":"42.1","Tissue RNA - duodenum [nTPM]":"28.7","Tissue RNA - endometrium 1 [nTPM]":"55.4","Tissue RNA - epididymis [nTPM]":"63.9","Tissue RNA - esophagus [nTPM]":"37.1","Tissue RNA - fallopian tube [nTPM]":"45.6","Tissue RNA - gallbladder [nTPM]":"23.9","Tissue RNA - heart muscle [nTPM]":"61.9","Tissue RNA - hippocampal formation [nTPM]":"65.3","Tissue RNA - hypothalamus [nTPM]":"77.5","Tissue RNA - kidney [nTPM]":"75.2","Tissue RNA - liver [nTPM]":"26.4","Tissue RNA - lung [nTPM]":"42.9","Tissue RNA - lymph node [nTPM]":"19.3","Tissue RNA - medulla oblongata [nTPM]":"74.9","Tissue RNA - midbrain [nTPM]":"86.9","Tissue RNA - ovary [nTPM]":"44.3","Tissue RNA - pancreas [nTPM]":"56.5","Tissue RNA - parathyroid gland [nTPM]":"66.7","Tissue RNA - pituitary gland [nTPM]":"95.1","Tissue RNA - placenta [nTPM]":"25.8","Tissue RNA - pons [nTPM]":"96.1","Tissue RNA - prostate [nTPM]":"59.5","Tissue RNA - rectum [nTPM]":"18.2","Tissue RNA - retina [nTPM]":"17.1","Tissue RNA - salivary gland [nTPM]":"48.7","Tissue RNA - seminal vesicle [nTPM]":"40.6","Tissue RNA - skeletal muscle [nTPM]":"54.3","Tissue RNA - skin 1 [nTPM]":"26.8","Tissue RNA - small intestine [nTPM]":"39.6","Tissue RNA - smooth muscle [nTPM]":"23.0","Tissue RNA - spinal cord [nTPM]":"67.9","Tissue RNA - spleen [nTPM]":"45.2","Tissue RNA - stomach 1 [nTPM]":"51.4","Tissue RNA - testis [nTPM]":"55.1","Tissue RNA - thalamus [nTPM]":"72.7","Tissue RNA - thymus [nTPM]":"15.2","Tissue RNA - thyroid gland [nTPM]":"71.1","Tissue RNA - tongue [nTPM]":"26.4","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"48.7","Tissue RNA - vagina [nTPM]":"37.7","Tissue RNA - white matter [nTPM]":"72.4","Cell RNA - A-431 [nTPM]":"40.0","Cell RNA - A549 [nTPM]":"231.7","Cell RNA - AF22 [nTPM]":"73.7","Cell RNA - AN3-CA [nTPM]":"128.5","Cell RNA - ASC diff [nTPM]":"77.9","Cell RNA - ASC TERT1 [nTPM]":"58.3","Cell RNA - BEWO [nTPM]":"55.3","Cell RNA - BJ [nTPM]":"45.0","Cell RNA - BJ hTERT+ [nTPM]":"86.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"96.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"64.4","Cell RNA - CACO-2 [nTPM]":"97.1","Cell RNA - CAPAN-2 [nTPM]":"62.3","Cell RNA - Daudi [nTPM]":"88.9","Cell RNA - EFO-21 [nTPM]":"62.8","Cell RNA - fHDF\/TERT166 [nTPM]":"95.1","Cell RNA - GAMG [nTPM]":"65.4","Cell RNA - HaCaT [nTPM]":"67.4","Cell RNA - HAP1 [nTPM]":"53.5","Cell RNA - HBEC3-KT [nTPM]":"92.1","Cell RNA - HBF TERT88 [nTPM]":"44.5","Cell RNA - HDLM-2 [nTPM]":"46.4","Cell RNA - HEK 293 [nTPM]":"86.0","Cell RNA - HEL [nTPM]":"49.3","Cell RNA - HeLa [nTPM]":"142.5","Cell RNA - Hep G2 [nTPM]":"182.4","Cell RNA - HHSteC [nTPM]":"84.1","Cell RNA - HL-60 [nTPM]":"46.1","Cell RNA - HMC-1 [nTPM]":"59.8","Cell RNA - HSkMC [nTPM]":"77.3","Cell RNA - hTCEpi [nTPM]":"44.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"93.1","Cell RNA - hTERT-HME1 [nTPM]":"62.3","Cell RNA - hTERT-RPE1 [nTPM]":"59.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.3","Cell RNA - JURKAT [nTPM]":"35.9","Cell RNA - K-562 [nTPM]":"51.5","Cell RNA - Karpas-707 [nTPM]":"109.6","Cell RNA - LHCN-M2 [nTPM]":"72.5","Cell RNA - MCF7 [nTPM]":"112.1","Cell RNA - MOLT-4 [nTPM]":"22.4","Cell RNA - NB-4 [nTPM]":"71.4","Cell RNA - NTERA-2 [nTPM]":"99.3","Cell RNA - OE19 [nTPM]":"48.7","Cell RNA - PC-3 [nTPM]":"133.5","Cell RNA - REH [nTPM]":"45.6","Cell RNA - RH-30 [nTPM]":"48.4","Cell RNA - RPMI-8226 [nTPM]":"207.5","Cell RNA - RPTEC TERT1 [nTPM]":"137.6","Cell RNA - RT4 [nTPM]":"93.6","Cell RNA - SCLC-21H [nTPM]":"92.7","Cell RNA - SH-SY5Y [nTPM]":"83.0","Cell RNA - SiHa [nTPM]":"49.1","Cell RNA - SK-BR-3 [nTPM]":"57.4","Cell RNA - SK-MEL-30 [nTPM]":"59.3","Cell RNA - SuSa [nTPM]":"82.9","Cell RNA - T-47d [nTPM]":"158.6","Cell RNA - THP-1 [nTPM]":"45.1","Cell RNA - TIME [nTPM]":"87.6","Cell RNA - U-138 MG [nTPM]":"98.8","Cell RNA - U-2 OS [nTPM]":"53.1","Cell RNA - U-2197 [nTPM]":"26.8","Cell RNA - U-251 MG [nTPM]":"63.5","Cell RNA - U-266\/70 [nTPM]":"74.0","Cell RNA - U-266\/84 [nTPM]":"56.2","Cell RNA - U-698 [nTPM]":"26.1","Cell RNA - U-87 MG [nTPM]":"110.3","Cell RNA - U-937 [nTPM]":"38.2","Cell RNA - WM-115 [nTPM]":"128.9","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"33.1","Blood RNA - eosinophil [nTPM]":"7.9","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"43.4","Blood RNA - MAIT T-cell [nTPM]":"12.1","Blood RNA - memory B-cell [nTPM]":"12.1","Blood RNA - memory CD4 T-cell [nTPM]":"8.0","Blood RNA - memory CD8 T-cell [nTPM]":"9.1","Blood RNA - myeloid DC [nTPM]":"54.2","Blood RNA - naive B-cell [nTPM]":"13.9","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"12.9","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"26.3","Blood RNA - plasmacytoid DC [nTPM]":"74.5","Blood RNA - T-reg [nTPM]":"8.5","Blood RNA - total PBMC [nTPM]":"16.9","Brain RNA - amygdala [nTPM]":"64.8","Brain RNA - basal ganglia [nTPM]":"67.8","Brain RNA - cerebellum [nTPM]":"70.5","Brain RNA - cerebral cortex [nTPM]":"79.3","Brain RNA - hippocampal formation [nTPM]":"65.3","Brain RNA - hypothalamus [nTPM]":"77.5","Brain RNA - medulla oblongata [nTPM]":"74.9","Brain RNA - midbrain [nTPM]":"86.9","Brain RNA - pons [nTPM]":"96.1","Brain RNA - spinal cord [nTPM]":"67.9","Brain RNA - thalamus [nTPM]":"72.7","Brain RNA - white matter [nTPM]":"72.4","Single Cell Type RNA - Adipocytes [nTPM]":"22.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.9","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"25.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.3","Single Cell Type RNA - dendritic cells [nTPM]":"17.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"59.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.1","Single Cell Type RNA - Endothelial cells [nTPM]":"26.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.9","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.1","Single Cell Type RNA - Fibroblasts [nTPM]":"25.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.1","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.5","Single Cell Type RNA - Hepatocytes [nTPM]":"7.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"21.6","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"20.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"21.8","Single Cell Type RNA - Muller glia cells [nTPM]":"30.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.6","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"27.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.4","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"26.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"42.5","Single Cell Type RNA - T-cells [nTPM]":"7.0","Single Cell Type RNA - Theca cells [nTPM]":"43.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.2"},{"Gene":"G6PD","Gene synonym":["G6PD1"],"Ensembl":"ENSG00000160211","Gene description":"Glucose-6-phosphate dehydrogenase","Uniprot":["P11413"],"Chromosome":"X","Position":"154531391-154547572","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"105.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"112.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"412.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"412.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"2333.8","MCF7":"883.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000247","HPA000834"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2400000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"HPA000247":"AB_1078978","HPA000834":"AB_1078977"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.45e-13"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.7","Tissue RNA - adrenal gland [nTPM]":"39.1","Tissue RNA - amygdala [nTPM]":"19.9","Tissue RNA - appendix [nTPM]":"30.2","Tissue RNA - basal ganglia [nTPM]":"21.8","Tissue RNA - bone marrow [nTPM]":"105.9","Tissue RNA - breast [nTPM]":"31.9","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"28.3","Tissue RNA - cervix [nTPM]":"20.6","Tissue RNA - choroid plexus [nTPM]":"20.0","Tissue RNA - colon [nTPM]":"13.9","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"21.6","Tissue RNA - epididymis [nTPM]":"13.3","Tissue RNA - esophagus [nTPM]":"54.3","Tissue RNA - fallopian tube [nTPM]":"19.3","Tissue RNA - gallbladder [nTPM]":"46.5","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"21.3","Tissue RNA - hypothalamus [nTPM]":"22.7","Tissue RNA - kidney [nTPM]":"12.7","Tissue RNA - liver [nTPM]":"6.5","Tissue RNA - lung [nTPM]":"29.4","Tissue RNA - lymph node [nTPM]":"28.9","Tissue RNA - medulla oblongata [nTPM]":"25.4","Tissue RNA - midbrain [nTPM]":"22.2","Tissue RNA - ovary [nTPM]":"24.1","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"9.6","Tissue RNA - pituitary gland [nTPM]":"27.5","Tissue RNA - placenta [nTPM]":"13.7","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"12.2","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"26.1","Tissue RNA - salivary gland [nTPM]":"21.2","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"21.3","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"25.6","Tissue RNA - spinal cord [nTPM]":"19.7","Tissue RNA - spleen [nTPM]":"26.9","Tissue RNA - stomach 1 [nTPM]":"18.1","Tissue RNA - testis [nTPM]":"54.0","Tissue RNA - thalamus [nTPM]":"26.1","Tissue RNA - thymus [nTPM]":"26.2","Tissue RNA - thyroid gland [nTPM]":"45.9","Tissue RNA - tongue [nTPM]":"5.1","Tissue RNA - tonsil [nTPM]":"37.2","Tissue RNA - urinary bladder [nTPM]":"33.8","Tissue RNA - vagina [nTPM]":"22.4","Tissue RNA - white matter [nTPM]":"21.9","Cell RNA - A-431 [nTPM]":"168.5","Cell RNA - A549 [nTPM]":"2333.8","Cell RNA - AF22 [nTPM]":"49.7","Cell RNA - AN3-CA [nTPM]":"189.7","Cell RNA - ASC diff [nTPM]":"207.2","Cell RNA - ASC TERT1 [nTPM]":"281.7","Cell RNA - BEWO [nTPM]":"43.5","Cell RNA - BJ [nTPM]":"116.0","Cell RNA - BJ hTERT+ [nTPM]":"341.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"120.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"205.8","Cell RNA - CACO-2 [nTPM]":"111.2","Cell RNA - CAPAN-2 [nTPM]":"61.9","Cell RNA - Daudi [nTPM]":"110.9","Cell RNA - EFO-21 [nTPM]":"174.1","Cell RNA - fHDF\/TERT166 [nTPM]":"274.3","Cell RNA - GAMG [nTPM]":"475.9","Cell RNA - HaCaT [nTPM]":"146.3","Cell RNA - HAP1 [nTPM]":"79.3","Cell RNA - HBEC3-KT [nTPM]":"202.5","Cell RNA - HBF TERT88 [nTPM]":"60.3","Cell RNA - HDLM-2 [nTPM]":"111.4","Cell RNA - HEK 293 [nTPM]":"55.0","Cell RNA - HEL [nTPM]":"116.8","Cell RNA - HeLa [nTPM]":"517.2","Cell RNA - Hep G2 [nTPM]":"244.6","Cell RNA - HHSteC [nTPM]":"401.6","Cell RNA - HL-60 [nTPM]":"117.8","Cell RNA - HMC-1 [nTPM]":"373.5","Cell RNA - HSkMC [nTPM]":"136.6","Cell RNA - hTCEpi [nTPM]":"58.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"233.9","Cell RNA - hTERT-HME1 [nTPM]":"49.8","Cell RNA - hTERT-RPE1 [nTPM]":"185.6","Cell RNA - HUVEC TERT2 [nTPM]":"252.5","Cell RNA - JURKAT [nTPM]":"79.8","Cell RNA - K-562 [nTPM]":"69.6","Cell RNA - Karpas-707 [nTPM]":"46.3","Cell RNA - LHCN-M2 [nTPM]":"218.4","Cell RNA - MCF7 [nTPM]":"883.9","Cell RNA - MOLT-4 [nTPM]":"77.5","Cell RNA - NB-4 [nTPM]":"93.0","Cell RNA - NTERA-2 [nTPM]":"35.3","Cell RNA - OE19 [nTPM]":"549.5","Cell RNA - PC-3 [nTPM]":"172.2","Cell RNA - REH [nTPM]":"74.9","Cell RNA - RH-30 [nTPM]":"28.4","Cell RNA - RPMI-8226 [nTPM]":"120.5","Cell RNA - RPTEC TERT1 [nTPM]":"357.1","Cell RNA - RT4 [nTPM]":"210.9","Cell RNA - SCLC-21H [nTPM]":"49.6","Cell RNA - SH-SY5Y [nTPM]":"62.0","Cell RNA - SiHa [nTPM]":"115.9","Cell RNA - SK-BR-3 [nTPM]":"444.5","Cell RNA - SK-MEL-30 [nTPM]":"99.9","Cell RNA - SuSa [nTPM]":"65.0","Cell RNA - T-47d [nTPM]":"67.1","Cell RNA - THP-1 [nTPM]":"99.4","Cell RNA - TIME [nTPM]":"289.8","Cell RNA - U-138 MG [nTPM]":"73.1","Cell RNA - U-2 OS [nTPM]":"250.0","Cell RNA - U-2197 [nTPM]":"102.5","Cell RNA - U-251 MG [nTPM]":"181.8","Cell RNA - U-266\/70 [nTPM]":"58.2","Cell RNA - U-266\/84 [nTPM]":"80.0","Cell RNA - U-698 [nTPM]":"189.8","Cell RNA - U-87 MG [nTPM]":"200.6","Cell RNA - U-937 [nTPM]":"77.5","Cell RNA - WM-115 [nTPM]":"150.9","Blood RNA - basophil [nTPM]":"166.1","Blood RNA - classical monocyte [nTPM]":"84.9","Blood RNA - eosinophil [nTPM]":"412.7","Blood RNA - gdT-cell [nTPM]":"50.3","Blood RNA - intermediate monocyte [nTPM]":"72.1","Blood RNA - MAIT T-cell [nTPM]":"32.1","Blood RNA - memory B-cell [nTPM]":"16.0","Blood RNA - memory CD4 T-cell [nTPM]":"13.7","Blood RNA - memory CD8 T-cell [nTPM]":"36.7","Blood RNA - myeloid DC [nTPM]":"40.1","Blood RNA - naive B-cell [nTPM]":"17.0","Blood RNA - naive CD4 T-cell [nTPM]":"16.5","Blood RNA - naive CD8 T-cell [nTPM]":"28.2","Blood RNA - neutrophil [nTPM]":"137.4","Blood RNA - NK-cell [nTPM]":"69.3","Blood RNA - non-classical monocyte [nTPM]":"63.5","Blood RNA - plasmacytoid DC [nTPM]":"18.9","Blood RNA - T-reg [nTPM]":"18.7","Blood RNA - total PBMC [nTPM]":"72.8","Brain RNA - amygdala [nTPM]":"19.9","Brain RNA - basal ganglia [nTPM]":"21.8","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"28.3","Brain RNA - hippocampal formation [nTPM]":"21.3","Brain RNA - hypothalamus [nTPM]":"22.7","Brain RNA - medulla oblongata [nTPM]":"25.4","Brain RNA - midbrain [nTPM]":"22.2","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"19.7","Brain RNA - thalamus [nTPM]":"26.1","Brain RNA - white matter [nTPM]":"21.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"21.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"22.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.6","Single Cell Type RNA - dendritic cells [nTPM]":"58.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"39.3","Single Cell Type RNA - Early spermatids [nTPM]":"10.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"37.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"37.5","Single Cell Type RNA - Granulosa cells [nTPM]":"26.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.6","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"58.2","Single Cell Type RNA - Langerhans cells [nTPM]":"26.0","Single Cell Type RNA - Late spermatids [nTPM]":"20.8","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"56.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"112.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.6","Single Cell Type RNA - NK-cells [nTPM]":"83.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.4","Single Cell Type RNA - Peritubular cells [nTPM]":"16.1","Single Cell Type RNA - Plasma cells [nTPM]":"21.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"32.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"32.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.3","Single Cell Type RNA - T-cells [nTPM]":"33.8","Single Cell Type RNA - Theca cells [nTPM]":"11.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"30.5"},{"Gene":"GFI1","Gene synonym":["GFI-1","GFI1A","ZNF163"],"Ensembl":"ENSG00000162676","Gene description":"Growth factor independent 1 transcriptional repressor","Uniprot":["Q99684"],"Chromosome":"1","Position":"92473043-92486925","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"53.7","lymphoid tissue":"31.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"14.2","Intestinal goblet cells":"12.4","NK-cells":"11.3","Plasma cells":"8.6","T-cells":"16.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"2.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"61.9","HMC-1":"47.5","NB-4":"64.7","THP-1":"127.7","U-937":"261.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011197"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011197":"AB_532302"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.68e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.27e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"53.7","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"2.8","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"9.4","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"31.2","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"1.6","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"5.3","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"61.9","Cell RNA - HMC-1 [nTPM]":"47.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"17.1","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"15.3","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"39.5","Cell RNA - NB-4 [nTPM]":"64.7","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"7.8","Cell RNA - RH-30 [nTPM]":"2.7","Cell RNA - RPMI-8226 [nTPM]":"3.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"127.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"22.2","Cell RNA - U-266\/84 [nTPM]":"1.6","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"261.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"16.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"HAX1","Gene synonym":["HAX-1","HCLSBP1","HS1BP1"],"Ensembl":"ENSG00000143575","Gene description":"HCLS1 associated protein X-1","Uniprot":["O00165"],"Chromosome":"1","Position":"154272589-154275875","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055141","HPA075289"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA055141":"AB_2682714","HPA075289":"AB_2686742"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"58.6","Tissue RNA - adrenal gland [nTPM]":"63.0","Tissue RNA - amygdala [nTPM]":"100.0","Tissue RNA - appendix [nTPM]":"43.6","Tissue RNA - basal ganglia [nTPM]":"105.5","Tissue RNA - bone marrow [nTPM]":"36.8","Tissue RNA - breast [nTPM]":"74.4","Tissue RNA - cerebellum [nTPM]":"105.2","Tissue RNA - cerebral cortex [nTPM]":"124.1","Tissue RNA - cervix [nTPM]":"60.0","Tissue RNA - choroid plexus [nTPM]":"100.6","Tissue RNA - colon [nTPM]":"62.0","Tissue RNA - duodenum [nTPM]":"48.0","Tissue RNA - endometrium 1 [nTPM]":"46.2","Tissue RNA - epididymis [nTPM]":"100.1","Tissue RNA - esophagus [nTPM]":"53.7","Tissue RNA - fallopian tube [nTPM]":"61.7","Tissue RNA - gallbladder [nTPM]":"40.4","Tissue RNA - heart muscle [nTPM]":"168.6","Tissue RNA - hippocampal formation [nTPM]":"100.5","Tissue RNA - hypothalamus [nTPM]":"107.9","Tissue RNA - kidney [nTPM]":"76.1","Tissue RNA - liver [nTPM]":"104.0","Tissue RNA - lung [nTPM]":"45.2","Tissue RNA - lymph node [nTPM]":"58.3","Tissue RNA - medulla oblongata [nTPM]":"102.1","Tissue RNA - midbrain [nTPM]":"99.9","Tissue RNA - ovary [nTPM]":"72.9","Tissue RNA - pancreas [nTPM]":"85.5","Tissue RNA - parathyroid gland [nTPM]":"84.9","Tissue RNA - pituitary gland [nTPM]":"88.6","Tissue RNA - placenta [nTPM]":"40.5","Tissue RNA - pons [nTPM]":"102.9","Tissue RNA - prostate [nTPM]":"55.5","Tissue RNA - rectum [nTPM]":"63.3","Tissue RNA - retina [nTPM]":"54.1","Tissue RNA - salivary gland [nTPM]":"85.8","Tissue RNA - seminal vesicle [nTPM]":"63.8","Tissue RNA - skeletal muscle [nTPM]":"256.7","Tissue RNA - skin 1 [nTPM]":"48.8","Tissue RNA - small intestine [nTPM]":"43.2","Tissue RNA - smooth muscle [nTPM]":"64.1","Tissue RNA - spinal cord [nTPM]":"105.1","Tissue RNA - spleen [nTPM]":"47.1","Tissue RNA - stomach 1 [nTPM]":"66.3","Tissue RNA - testis [nTPM]":"69.5","Tissue RNA - thalamus [nTPM]":"105.0","Tissue RNA - thymus [nTPM]":"67.4","Tissue RNA - thyroid gland [nTPM]":"69.2","Tissue RNA - tongue [nTPM]":"242.7","Tissue RNA - tonsil [nTPM]":"77.3","Tissue RNA - urinary bladder [nTPM]":"58.5","Tissue RNA - vagina [nTPM]":"48.9","Tissue RNA - white matter [nTPM]":"103.3","Cell RNA - A-431 [nTPM]":"115.3","Cell RNA - A549 [nTPM]":"100.7","Cell RNA - AF22 [nTPM]":"84.2","Cell RNA - AN3-CA [nTPM]":"178.0","Cell RNA - ASC diff [nTPM]":"100.3","Cell RNA - ASC TERT1 [nTPM]":"111.8","Cell RNA - BEWO [nTPM]":"132.1","Cell RNA - BJ [nTPM]":"109.8","Cell RNA - BJ hTERT+ [nTPM]":"178.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"227.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"207.5","Cell RNA - CACO-2 [nTPM]":"126.6","Cell RNA - CAPAN-2 [nTPM]":"125.7","Cell RNA - Daudi [nTPM]":"170.9","Cell RNA - EFO-21 [nTPM]":"150.7","Cell RNA - fHDF\/TERT166 [nTPM]":"188.0","Cell RNA - GAMG [nTPM]":"105.9","Cell RNA - HaCaT [nTPM]":"100.0","Cell RNA - HAP1 [nTPM]":"190.7","Cell RNA - HBEC3-KT [nTPM]":"151.3","Cell RNA - HBF TERT88 [nTPM]":"172.3","Cell RNA - HDLM-2 [nTPM]":"171.0","Cell RNA - HEK 293 [nTPM]":"140.8","Cell RNA - HEL [nTPM]":"81.8","Cell RNA - HeLa [nTPM]":"76.5","Cell RNA - Hep G2 [nTPM]":"104.4","Cell RNA - HHSteC [nTPM]":"221.5","Cell RNA - HL-60 [nTPM]":"172.5","Cell RNA - HMC-1 [nTPM]":"167.0","Cell RNA - HSkMC [nTPM]":"104.4","Cell RNA - hTCEpi [nTPM]":"274.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"172.8","Cell RNA - hTERT-HME1 [nTPM]":"206.3","Cell RNA - hTERT-RPE1 [nTPM]":"82.2","Cell RNA - HUVEC TERT2 [nTPM]":"129.7","Cell RNA - JURKAT [nTPM]":"246.1","Cell RNA - K-562 [nTPM]":"166.1","Cell RNA - Karpas-707 [nTPM]":"244.8","Cell RNA - LHCN-M2 [nTPM]":"145.6","Cell RNA - MCF7 [nTPM]":"260.9","Cell RNA - MOLT-4 [nTPM]":"169.9","Cell RNA - NB-4 [nTPM]":"136.1","Cell RNA - NTERA-2 [nTPM]":"88.7","Cell RNA - OE19 [nTPM]":"277.4","Cell RNA - PC-3 [nTPM]":"213.2","Cell RNA - REH [nTPM]":"121.3","Cell RNA - RH-30 [nTPM]":"59.7","Cell RNA - RPMI-8226 [nTPM]":"326.7","Cell RNA - RPTEC TERT1 [nTPM]":"115.4","Cell RNA - RT4 [nTPM]":"60.8","Cell RNA - SCLC-21H [nTPM]":"123.2","Cell RNA - SH-SY5Y [nTPM]":"121.7","Cell RNA - SiHa [nTPM]":"96.4","Cell RNA - SK-BR-3 [nTPM]":"228.2","Cell RNA - SK-MEL-30 [nTPM]":"326.7","Cell RNA - SuSa [nTPM]":"137.5","Cell RNA - T-47d [nTPM]":"190.0","Cell RNA - THP-1 [nTPM]":"454.8","Cell RNA - TIME [nTPM]":"64.5","Cell RNA - U-138 MG [nTPM]":"92.7","Cell RNA - U-2 OS [nTPM]":"122.7","Cell RNA - U-2197 [nTPM]":"97.7","Cell RNA - U-251 MG [nTPM]":"148.8","Cell RNA - U-266\/70 [nTPM]":"284.8","Cell RNA - U-266\/84 [nTPM]":"315.9","Cell RNA - U-698 [nTPM]":"315.3","Cell RNA - U-87 MG [nTPM]":"139.0","Cell RNA - U-937 [nTPM]":"158.4","Cell RNA - WM-115 [nTPM]":"153.4","Blood RNA - basophil [nTPM]":"266.5","Blood RNA - classical monocyte [nTPM]":"97.6","Blood RNA - eosinophil [nTPM]":"215.4","Blood RNA - gdT-cell [nTPM]":"113.7","Blood RNA - intermediate monocyte [nTPM]":"121.9","Blood RNA - MAIT T-cell [nTPM]":"129.3","Blood RNA - memory B-cell [nTPM]":"136.1","Blood RNA - memory CD4 T-cell [nTPM]":"139.2","Blood RNA - memory CD8 T-cell [nTPM]":"128.3","Blood RNA - myeloid DC [nTPM]":"118.6","Blood RNA - naive B-cell [nTPM]":"142.2","Blood RNA - naive CD4 T-cell [nTPM]":"166.5","Blood RNA - naive CD8 T-cell [nTPM]":"132.6","Blood RNA - neutrophil [nTPM]":"61.1","Blood RNA - NK-cell [nTPM]":"116.7","Blood RNA - non-classical monocyte [nTPM]":"150.1","Blood RNA - plasmacytoid DC [nTPM]":"122.8","Blood RNA - T-reg [nTPM]":"183.3","Blood RNA - total PBMC [nTPM]":"163.9","Brain RNA - amygdala [nTPM]":"100.0","Brain RNA - basal ganglia [nTPM]":"105.5","Brain RNA - cerebellum [nTPM]":"105.2","Brain RNA - cerebral cortex [nTPM]":"124.1","Brain RNA - hippocampal formation [nTPM]":"100.5","Brain RNA - hypothalamus [nTPM]":"107.9","Brain RNA - medulla oblongata [nTPM]":"102.1","Brain RNA - midbrain [nTPM]":"99.9","Brain RNA - pons [nTPM]":"102.9","Brain RNA - spinal cord [nTPM]":"105.1","Brain RNA - thalamus [nTPM]":"105.0","Brain RNA - white matter [nTPM]":"103.3","Single Cell Type RNA - Adipocytes [nTPM]":"69.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.6","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"125.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"112.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"118.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.9","Single Cell Type RNA - Bipolar cells [nTPM]":"57.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"92.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"123.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"106.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"71.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"84.8","Single Cell Type RNA - dendritic cells [nTPM]":"76.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"181.9","Single Cell Type RNA - Ductal cells [nTPM]":"93.3","Single Cell Type RNA - Early spermatids [nTPM]":"147.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.6","Single Cell Type RNA - Endothelial cells [nTPM]":"65.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"57.6","Single Cell Type RNA - Erythroid cells [nTPM]":"66.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"106.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"132.1","Single Cell Type RNA - Fibroblasts [nTPM]":"62.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.0","Single Cell Type RNA - granulocytes [nTPM]":"99.6","Single Cell Type RNA - Granulosa cells [nTPM]":"80.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"61.4","Single Cell Type RNA - Hepatocytes [nTPM]":"90.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"98.7","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"67.1","Single Cell Type RNA - Ionocytes [nTPM]":"91.6","Single Cell Type RNA - Kupffer cells [nTPM]":"63.9","Single Cell Type RNA - Langerhans cells [nTPM]":"79.3","Single Cell Type RNA - Late spermatids [nTPM]":"104.6","Single Cell Type RNA - Leydig cells [nTPM]":"61.2","Single Cell Type RNA - Macrophages [nTPM]":"66.8","Single Cell Type RNA - Melanocytes [nTPM]":"87.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"128.5","Single Cell Type RNA - Muller glia cells [nTPM]":"91.1","Single Cell Type RNA - NK-cells [nTPM]":"91.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"84.6","Single Cell Type RNA - Paneth cells [nTPM]":"63.6","Single Cell Type RNA - Peritubular cells [nTPM]":"62.1","Single Cell Type RNA - Plasma cells [nTPM]":"192.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"92.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"128.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"141.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"97.5","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"58.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"76.0","Single Cell Type RNA - Spermatocytes [nTPM]":"223.8","Single Cell Type RNA - Spermatogonia [nTPM]":"112.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"71.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"76.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.8","Single Cell Type RNA - T-cells [nTPM]":"97.7","Single Cell Type RNA - Theca cells [nTPM]":"74.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"71.7","Single Cell Type RNA - Urothelial cells [nTPM]":"101.7"},{"Gene":"HELLS","Gene synonym":["LSH","Nbla10143","PASG","SMARCA6"],"Ensembl":"ENSG00000119969","Gene description":"Helicase, lymphoid specific","Uniprot":["Q9NRZ9"],"Chromosome":"10","Position":"94501434-94613905","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","Helicase","Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"16.3","lymphoid tissue":"15.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"182.0","Spermatogonia":"173.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"16.1"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"5.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"36.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004491","HPA063242"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"CAB004491":"AB_627895","HPA063242":"AB_2684968"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-5"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-13"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"6.4","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"16.3","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"3.2","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"5.1","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"4.3","Tissue RNA - stomach 1 [nTPM]":"3.7","Tissue RNA - testis [nTPM]":"12.8","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"15.9","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"12.6","Tissue RNA - urinary bladder [nTPM]":"3.6","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"1.5","Cell RNA - A-431 [nTPM]":"57.7","Cell RNA - A549 [nTPM]":"55.4","Cell RNA - AF22 [nTPM]":"70.6","Cell RNA - AN3-CA [nTPM]":"90.1","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"6.4","Cell RNA - BEWO [nTPM]":"37.4","Cell RNA - BJ [nTPM]":"42.9","Cell RNA - BJ hTERT+ [nTPM]":"27.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"34.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.6","Cell RNA - CACO-2 [nTPM]":"70.3","Cell RNA - CAPAN-2 [nTPM]":"45.5","Cell RNA - Daudi [nTPM]":"70.0","Cell RNA - EFO-21 [nTPM]":"16.7","Cell RNA - fHDF\/TERT166 [nTPM]":"15.5","Cell RNA - GAMG [nTPM]":"29.1","Cell RNA - HaCaT [nTPM]":"56.3","Cell RNA - HAP1 [nTPM]":"40.9","Cell RNA - HBEC3-KT [nTPM]":"34.9","Cell RNA - HBF TERT88 [nTPM]":"50.7","Cell RNA - HDLM-2 [nTPM]":"68.5","Cell RNA - HEK 293 [nTPM]":"45.5","Cell RNA - HEL [nTPM]":"37.3","Cell RNA - HeLa [nTPM]":"56.3","Cell RNA - Hep G2 [nTPM]":"58.0","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"71.2","Cell RNA - HMC-1 [nTPM]":"31.6","Cell RNA - HSkMC [nTPM]":"3.6","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.1","Cell RNA - hTERT-HME1 [nTPM]":"20.0","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"24.0","Cell RNA - JURKAT [nTPM]":"46.0","Cell RNA - K-562 [nTPM]":"20.7","Cell RNA - Karpas-707 [nTPM]":"43.5","Cell RNA - LHCN-M2 [nTPM]":"43.1","Cell RNA - MCF7 [nTPM]":"54.9","Cell RNA - MOLT-4 [nTPM]":"75.2","Cell RNA - NB-4 [nTPM]":"35.6","Cell RNA - NTERA-2 [nTPM]":"73.4","Cell RNA - OE19 [nTPM]":"42.3","Cell RNA - PC-3 [nTPM]":"24.1","Cell RNA - REH [nTPM]":"70.3","Cell RNA - RH-30 [nTPM]":"62.1","Cell RNA - RPMI-8226 [nTPM]":"16.3","Cell RNA - RPTEC TERT1 [nTPM]":"24.2","Cell RNA - RT4 [nTPM]":"72.2","Cell RNA - SCLC-21H [nTPM]":"28.4","Cell RNA - SH-SY5Y [nTPM]":"22.8","Cell RNA - SiHa [nTPM]":"50.3","Cell RNA - SK-BR-3 [nTPM]":"14.5","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"59.0","Cell RNA - T-47d [nTPM]":"60.9","Cell RNA - THP-1 [nTPM]":"23.1","Cell RNA - TIME [nTPM]":"17.2","Cell RNA - U-138 MG [nTPM]":"38.4","Cell RNA - U-2 OS [nTPM]":"19.4","Cell RNA - U-2197 [nTPM]":"35.4","Cell RNA - U-251 MG [nTPM]":"52.4","Cell RNA - U-266\/70 [nTPM]":"22.3","Cell RNA - U-266\/84 [nTPM]":"47.6","Cell RNA - U-698 [nTPM]":"74.5","Cell RNA - U-87 MG [nTPM]":"19.0","Cell RNA - U-937 [nTPM]":"42.8","Cell RNA - WM-115 [nTPM]":"17.9","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"7.0","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"18.8","Blood RNA - memory CD4 T-cell [nTPM]":"11.4","Blood RNA - memory CD8 T-cell [nTPM]":"9.4","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"23.2","Blood RNA - naive CD4 T-cell [nTPM]":"5.2","Blood RNA - naive CD8 T-cell [nTPM]":"7.7","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"10.2","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"36.8","Blood RNA - T-reg [nTPM]":"19.7","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"19.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"16.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.3","Single Cell Type RNA - dendritic cells [nTPM]":"13.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"50.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.4","Single Cell Type RNA - Fibroblasts [nTPM]":"13.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.3","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"60.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"10.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"4.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"37.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.4","Single Cell Type RNA - Spermatocytes [nTPM]":"182.0","Single Cell Type RNA - Spermatogonia [nTPM]":"173.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"15.7","Single Cell Type RNA - Theca cells [nTPM]":"16.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.9","Single Cell Type RNA - Urothelial cells [nTPM]":"11.7"},{"Gene":"ICOS","Gene synonym":["AILIM","CD278"],"Ensembl":"ENSG00000163600","Gene description":"Inducible T cell costimulator","Uniprot":["Q9Y6W8"],"Chromosome":"2","Position":"203936763-203961577","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"16.5","lymphoid tissue":"20.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"T-cells":"81.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"29.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"54","RNA blood lineage specific nTPM":{"T-cells":"29.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"HEL":"4.6","MOLT-4":"12.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032575","HPA034865"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Actin filaments"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB032575":"AB_2122593","HPA034865":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"16.5","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"2.6","Tissue RNA - lymph node [nTPM]":"14.3","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"1.3","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"20.2","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"16.2","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"12.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"4.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"15.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"15.7","Blood RNA - naive CD8 T-cell [nTPM]":"7.2","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"29.1","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"5.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"4.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"5.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"81.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"IFNGR1","Gene synonym":["CD119","IFNGR"],"Ensembl":"ENSG00000027697","Gene description":"Interferon gamma receptor 1","Uniprot":["P15260"],"Chromosome":"6","Position":"137197485-137219449","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"867.1","Club cells":"405.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025889","HPA029213","HPA063871"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB025889":null,"HPA029213":"AB_10601023","HPA063871":"AB_2685138"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.38e-3"},"Tissue RNA - adipose tissue [nTPM]":"155.5","Tissue RNA - adrenal gland [nTPM]":"59.3","Tissue RNA - amygdala [nTPM]":"54.6","Tissue RNA - appendix [nTPM]":"131.5","Tissue RNA - basal ganglia [nTPM]":"57.8","Tissue RNA - bone marrow [nTPM]":"146.2","Tissue RNA - breast [nTPM]":"121.4","Tissue RNA - cerebellum [nTPM]":"64.5","Tissue RNA - cerebral cortex [nTPM]":"72.1","Tissue RNA - cervix [nTPM]":"74.1","Tissue RNA - choroid plexus [nTPM]":"56.8","Tissue RNA - colon [nTPM]":"74.7","Tissue RNA - duodenum [nTPM]":"97.9","Tissue RNA - endometrium 1 [nTPM]":"58.1","Tissue RNA - epididymis [nTPM]":"67.4","Tissue RNA - esophagus [nTPM]":"65.0","Tissue RNA - fallopian tube [nTPM]":"55.7","Tissue RNA - gallbladder [nTPM]":"88.4","Tissue RNA - heart muscle [nTPM]":"103.7","Tissue RNA - hippocampal formation [nTPM]":"53.1","Tissue RNA - hypothalamus [nTPM]":"59.9","Tissue RNA - kidney [nTPM]":"44.4","Tissue RNA - liver [nTPM]":"104.0","Tissue RNA - lung [nTPM]":"153.8","Tissue RNA - lymph node [nTPM]":"140.2","Tissue RNA - medulla oblongata [nTPM]":"71.9","Tissue RNA - midbrain [nTPM]":"60.3","Tissue RNA - ovary [nTPM]":"43.3","Tissue RNA - pancreas [nTPM]":"44.5","Tissue RNA - parathyroid gland [nTPM]":"47.4","Tissue RNA - pituitary gland [nTPM]":"26.3","Tissue RNA - placenta [nTPM]":"86.1","Tissue RNA - pons [nTPM]":"75.9","Tissue RNA - prostate [nTPM]":"53.2","Tissue RNA - rectum [nTPM]":"74.4","Tissue RNA - retina [nTPM]":"40.4","Tissue RNA - salivary gland [nTPM]":"57.7","Tissue RNA - seminal vesicle [nTPM]":"57.4","Tissue RNA - skeletal muscle [nTPM]":"58.3","Tissue RNA - skin 1 [nTPM]":"66.2","Tissue RNA - small intestine [nTPM]":"101.2","Tissue RNA - smooth muscle [nTPM]":"75.9","Tissue RNA - spinal cord [nTPM]":"69.2","Tissue RNA - spleen [nTPM]":"165.9","Tissue RNA - stomach 1 [nTPM]":"51.3","Tissue RNA - testis [nTPM]":"27.9","Tissue RNA - thalamus [nTPM]":"59.9","Tissue RNA - thymus [nTPM]":"69.2","Tissue RNA - thyroid gland [nTPM]":"58.3","Tissue RNA - tongue [nTPM]":"75.5","Tissue RNA - tonsil [nTPM]":"135.2","Tissue RNA - urinary bladder [nTPM]":"112.6","Tissue RNA - vagina [nTPM]":"58.0","Tissue RNA - white matter [nTPM]":"85.0","Cell RNA - A-431 [nTPM]":"23.2","Cell RNA - A549 [nTPM]":"23.4","Cell RNA - AF22 [nTPM]":"25.1","Cell RNA - AN3-CA [nTPM]":"33.4","Cell RNA - ASC diff [nTPM]":"166.8","Cell RNA - ASC TERT1 [nTPM]":"86.7","Cell RNA - BEWO [nTPM]":"23.0","Cell RNA - BJ [nTPM]":"67.0","Cell RNA - BJ hTERT+ [nTPM]":"90.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"53.3","Cell RNA - CACO-2 [nTPM]":"148.7","Cell RNA - CAPAN-2 [nTPM]":"39.8","Cell RNA - Daudi [nTPM]":"24.5","Cell RNA - EFO-21 [nTPM]":"99.2","Cell RNA - fHDF\/TERT166 [nTPM]":"36.1","Cell RNA - GAMG [nTPM]":"55.1","Cell RNA - HaCaT [nTPM]":"130.0","Cell RNA - HAP1 [nTPM]":"24.1","Cell RNA - HBEC3-KT [nTPM]":"62.6","Cell RNA - HBF TERT88 [nTPM]":"51.5","Cell RNA - HDLM-2 [nTPM]":"49.4","Cell RNA - HEK 293 [nTPM]":"37.4","Cell RNA - HEL [nTPM]":"36.1","Cell RNA - HeLa [nTPM]":"23.3","Cell RNA - Hep G2 [nTPM]":"192.9","Cell RNA - HHSteC [nTPM]":"97.3","Cell RNA - HL-60 [nTPM]":"112.9","Cell RNA - HMC-1 [nTPM]":"46.6","Cell RNA - HSkMC [nTPM]":"195.9","Cell RNA - hTCEpi [nTPM]":"232.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.3","Cell RNA - hTERT-HME1 [nTPM]":"51.4","Cell RNA - hTERT-RPE1 [nTPM]":"36.1","Cell RNA - HUVEC TERT2 [nTPM]":"48.7","Cell RNA - JURKAT [nTPM]":"29.1","Cell RNA - K-562 [nTPM]":"32.0","Cell RNA - Karpas-707 [nTPM]":"34.9","Cell RNA - LHCN-M2 [nTPM]":"29.2","Cell RNA - MCF7 [nTPM]":"27.7","Cell RNA - MOLT-4 [nTPM]":"17.7","Cell RNA - NB-4 [nTPM]":"47.0","Cell RNA - NTERA-2 [nTPM]":"22.0","Cell RNA - OE19 [nTPM]":"191.9","Cell RNA - PC-3 [nTPM]":"18.6","Cell RNA - REH [nTPM]":"51.3","Cell RNA - RH-30 [nTPM]":"28.4","Cell RNA - RPMI-8226 [nTPM]":"32.1","Cell RNA - RPTEC TERT1 [nTPM]":"65.5","Cell RNA - RT4 [nTPM]":"104.4","Cell RNA - SCLC-21H [nTPM]":"27.4","Cell RNA - SH-SY5Y [nTPM]":"39.5","Cell RNA - SiHa [nTPM]":"77.3","Cell RNA - SK-BR-3 [nTPM]":"41.9","Cell RNA - SK-MEL-30 [nTPM]":"57.5","Cell RNA - SuSa [nTPM]":"47.8","Cell RNA - T-47d [nTPM]":"15.5","Cell RNA - THP-1 [nTPM]":"68.7","Cell RNA - TIME [nTPM]":"71.1","Cell RNA - U-138 MG [nTPM]":"36.2","Cell RNA - U-2 OS [nTPM]":"27.7","Cell RNA - U-2197 [nTPM]":"48.5","Cell RNA - U-251 MG [nTPM]":"31.8","Cell RNA - U-266\/70 [nTPM]":"25.3","Cell RNA - U-266\/84 [nTPM]":"25.5","Cell RNA - U-698 [nTPM]":"23.8","Cell RNA - U-87 MG [nTPM]":"19.4","Cell RNA - U-937 [nTPM]":"69.2","Cell RNA - WM-115 [nTPM]":"36.5","Blood RNA - basophil [nTPM]":"158.6","Blood RNA - classical monocyte [nTPM]":"518.4","Blood RNA - eosinophil [nTPM]":"356.3","Blood RNA - gdT-cell [nTPM]":"106.9","Blood RNA - intermediate monocyte [nTPM]":"502.6","Blood RNA - MAIT T-cell [nTPM]":"224.7","Blood RNA - memory B-cell [nTPM]":"91.3","Blood RNA - memory CD4 T-cell [nTPM]":"60.0","Blood RNA - memory CD8 T-cell [nTPM]":"90.0","Blood RNA - myeloid DC [nTPM]":"309.4","Blood RNA - naive B-cell [nTPM]":"98.3","Blood RNA - naive CD4 T-cell [nTPM]":"39.2","Blood RNA - naive CD8 T-cell [nTPM]":"43.1","Blood RNA - neutrophil [nTPM]":"736.0","Blood RNA - NK-cell [nTPM]":"48.4","Blood RNA - non-classical monocyte [nTPM]":"375.6","Blood RNA - plasmacytoid DC [nTPM]":"85.1","Blood RNA - T-reg [nTPM]":"48.0","Blood RNA - total PBMC [nTPM]":"519.3","Brain RNA - amygdala [nTPM]":"54.6","Brain RNA - basal ganglia [nTPM]":"57.8","Brain RNA - cerebellum [nTPM]":"64.5","Brain RNA - cerebral cortex [nTPM]":"72.1","Brain RNA - hippocampal formation [nTPM]":"53.1","Brain RNA - hypothalamus [nTPM]":"59.9","Brain RNA - medulla oblongata [nTPM]":"71.9","Brain RNA - midbrain [nTPM]":"60.3","Brain RNA - pons [nTPM]":"75.9","Brain RNA - spinal cord [nTPM]":"69.2","Brain RNA - thalamus [nTPM]":"59.9","Brain RNA - white matter [nTPM]":"85.0","Single Cell Type RNA - Adipocytes [nTPM]":"298.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.9","Single Cell Type RNA - Astrocytes [nTPM]":"21.5","Single Cell Type RNA - B-cells [nTPM]":"76.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"127.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"177.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"867.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"84.2","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"405.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.5","Single Cell Type RNA - dendritic cells [nTPM]":"240.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"111.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"74.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"91.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.7","Single Cell Type RNA - Endothelial cells [nTPM]":"110.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"25.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"101.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"67.1","Single Cell Type RNA - Fibroblasts [nTPM]":"94.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"112.8","Single Cell Type RNA - granulocytes [nTPM]":"63.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"149.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.5","Single Cell Type RNA - Ionocytes [nTPM]":"270.6","Single Cell Type RNA - Kupffer cells [nTPM]":"326.2","Single Cell Type RNA - Langerhans cells [nTPM]":"220.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"44.1","Single Cell Type RNA - Macrophages [nTPM]":"261.7","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"147.1","Single Cell Type RNA - monocytes [nTPM]":"138.4","Single Cell Type RNA - Muller glia cells [nTPM]":"23.5","Single Cell Type RNA - NK-cells [nTPM]":"52.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"44.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"76.0","Single Cell Type RNA - Paneth cells [nTPM]":"57.6","Single Cell Type RNA - Peritubular cells [nTPM]":"49.2","Single Cell Type RNA - Plasma cells [nTPM]":"74.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"129.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"82.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"150.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"75.7","Single Cell Type RNA - Spermatocytes [nTPM]":"14.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"113.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"209.9","Single Cell Type RNA - T-cells [nTPM]":"121.5","Single Cell Type RNA - Theca cells [nTPM]":"48.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.9","Single Cell Type RNA - Urothelial cells [nTPM]":"140.2"},{"Gene":"IFNGR2","Gene synonym":["AF-1","IFNGT1"],"Ensembl":"ENSG00000159128","Gene description":"Interferon gamma receptor 2","Uniprot":["P38484"],"Chromosome":"21","Position":"33403413-33479348","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Prostatic glandular cells":"433.1","Urothelial cells":"602.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"661.8"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"76.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001535"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA001535":"AB_1078432"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.13e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-3"},"Tissue RNA - adipose tissue [nTPM]":"72.9","Tissue RNA - adrenal gland [nTPM]":"41.1","Tissue RNA - amygdala [nTPM]":"5.9","Tissue RNA - appendix [nTPM]":"8.6","Tissue RNA - basal ganglia [nTPM]":"7.0","Tissue RNA - bone marrow [nTPM]":"46.6","Tissue RNA - breast [nTPM]":"65.6","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"8.2","Tissue RNA - cervix [nTPM]":"48.3","Tissue RNA - choroid plexus [nTPM]":"7.9","Tissue RNA - colon [nTPM]":"46.8","Tissue RNA - duodenum [nTPM]":"14.2","Tissue RNA - endometrium 1 [nTPM]":"31.2","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"67.4","Tissue RNA - fallopian tube [nTPM]":"37.8","Tissue RNA - gallbladder [nTPM]":"11.6","Tissue RNA - heart muscle [nTPM]":"46.4","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"11.2","Tissue RNA - kidney [nTPM]":"53.1","Tissue RNA - liver [nTPM]":"43.1","Tissue RNA - lung [nTPM]":"61.8","Tissue RNA - lymph node [nTPM]":"10.6","Tissue RNA - medulla oblongata [nTPM]":"8.8","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"38.8","Tissue RNA - pancreas [nTPM]":"32.0","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"37.8","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"48.2","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"64.5","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"30.0","Tissue RNA - skin 1 [nTPM]":"53.3","Tissue RNA - small intestine [nTPM]":"51.6","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"80.8","Tissue RNA - stomach 1 [nTPM]":"35.8","Tissue RNA - testis [nTPM]":"29.5","Tissue RNA - thalamus [nTPM]":"12.2","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"52.3","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"11.9","Tissue RNA - urinary bladder [nTPM]":"46.4","Tissue RNA - vagina [nTPM]":"56.8","Tissue RNA - white matter [nTPM]":"14.0","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"10.2","Cell RNA - AF22 [nTPM]":"5.9","Cell RNA - AN3-CA [nTPM]":"9.7","Cell RNA - ASC diff [nTPM]":"16.6","Cell RNA - ASC TERT1 [nTPM]":"28.2","Cell RNA - BEWO [nTPM]":"13.1","Cell RNA - BJ [nTPM]":"30.4","Cell RNA - BJ hTERT+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.8","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"7.7","Cell RNA - Daudi [nTPM]":"15.6","Cell RNA - EFO-21 [nTPM]":"19.8","Cell RNA - fHDF\/TERT166 [nTPM]":"23.8","Cell RNA - GAMG [nTPM]":"24.2","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"25.6","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"76.3","Cell RNA - HEK 293 [nTPM]":"44.9","Cell RNA - HEL [nTPM]":"6.0","Cell RNA - HeLa [nTPM]":"5.0","Cell RNA - Hep G2 [nTPM]":"12.2","Cell RNA - HHSteC [nTPM]":"11.0","Cell RNA - HL-60 [nTPM]":"19.5","Cell RNA - HMC-1 [nTPM]":"17.7","Cell RNA - HSkMC [nTPM]":"21.4","Cell RNA - hTCEpi [nTPM]":"17.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.7","Cell RNA - hTERT-HME1 [nTPM]":"16.6","Cell RNA - hTERT-RPE1 [nTPM]":"15.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"9.9","Cell RNA - K-562 [nTPM]":"33.4","Cell RNA - Karpas-707 [nTPM]":"11.9","Cell RNA - LHCN-M2 [nTPM]":"10.2","Cell RNA - MCF7 [nTPM]":"4.4","Cell RNA - MOLT-4 [nTPM]":"5.0","Cell RNA - NB-4 [nTPM]":"23.2","Cell RNA - NTERA-2 [nTPM]":"18.1","Cell RNA - OE19 [nTPM]":"15.8","Cell RNA - PC-3 [nTPM]":"48.0","Cell RNA - REH [nTPM]":"20.2","Cell RNA - RH-30 [nTPM]":"14.1","Cell RNA - RPMI-8226 [nTPM]":"19.6","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"7.9","Cell RNA - SH-SY5Y [nTPM]":"15.5","Cell RNA - SiHa [nTPM]":"19.3","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"38.4","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"17.7","Cell RNA - TIME [nTPM]":"30.8","Cell RNA - U-138 MG [nTPM]":"10.1","Cell RNA - U-2 OS [nTPM]":"22.0","Cell RNA - U-2197 [nTPM]":"8.9","Cell RNA - U-251 MG [nTPM]":"8.8","Cell RNA - U-266\/70 [nTPM]":"24.6","Cell RNA - U-266\/84 [nTPM]":"28.2","Cell RNA - U-698 [nTPM]":"25.4","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"23.3","Cell RNA - WM-115 [nTPM]":"44.7","Blood RNA - basophil [nTPM]":"221.7","Blood RNA - classical monocyte [nTPM]":"283.8","Blood RNA - eosinophil [nTPM]":"181.7","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"281.2","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"145.6","Blood RNA - memory CD4 T-cell [nTPM]":"16.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"104.0","Blood RNA - naive B-cell [nTPM]":"158.2","Blood RNA - naive CD4 T-cell [nTPM]":"37.7","Blood RNA - naive CD8 T-cell [nTPM]":"16.3","Blood RNA - neutrophil [nTPM]":"661.8","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"314.8","Blood RNA - plasmacytoid DC [nTPM]":"31.9","Blood RNA - T-reg [nTPM]":"19.2","Blood RNA - total PBMC [nTPM]":"198.5","Brain RNA - amygdala [nTPM]":"5.9","Brain RNA - basal ganglia [nTPM]":"7.0","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"8.2","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"11.2","Brain RNA - medulla oblongata [nTPM]":"8.8","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"12.2","Brain RNA - white matter [nTPM]":"14.0","Single Cell Type RNA - Adipocytes [nTPM]":"72.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"101.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"72.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"225.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"164.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"147.4","Single Cell Type RNA - Bipolar cells [nTPM]":"9.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"58.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.6","Single Cell Type RNA - dendritic cells [nTPM]":"11.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"185.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"117.8","Single Cell Type RNA - Early spermatids [nTPM]":"44.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.0","Single Cell Type RNA - Endothelial cells [nTPM]":"55.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.6","Single Cell Type RNA - Erythroid cells [nTPM]":"17.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"55.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"86.1","Single Cell Type RNA - Fibroblasts [nTPM]":"66.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"62.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.4","Single Cell Type RNA - granulocytes [nTPM]":"60.3","Single Cell Type RNA - Granulosa cells [nTPM]":"52.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.0","Single Cell Type RNA - Hepatocytes [nTPM]":"29.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"167.6","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.2","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"154.5","Single Cell Type RNA - Langerhans cells [nTPM]":"146.7","Single Cell Type RNA - Late spermatids [nTPM]":"60.8","Single Cell Type RNA - Leydig cells [nTPM]":"42.0","Single Cell Type RNA - Macrophages [nTPM]":"190.8","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"246.6","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"138.6","Single Cell Type RNA - Paneth cells [nTPM]":"150.3","Single Cell Type RNA - Peritubular cells [nTPM]":"32.7","Single Cell Type RNA - Plasma cells [nTPM]":"67.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"433.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"151.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"61.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"90.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"70.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"16.9","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.3","Single Cell Type RNA - Urothelial cells [nTPM]":"602.7"},{"Gene":"IGLL1","Gene synonym":["14.1","CD179B","IGL5","IGLL","IGVPB"],"Ensembl":"ENSG00000128322","Gene description":"Immunoglobulin lambda like polypeptide 1","Uniprot":["P15814"],"Chromosome":"22","Position":"23573125-23580302","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"70.0","testis":"25.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Early spermatids":"78.0","Late spermatids":"140.7","Melanocytes":"119.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"endometrial cancer":"0.5","lung cancer":"0.5","stomach cancer":"2.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"memory B-cell":"12.0","naive B-cell":"14.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"B-cells":"14.8"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"32","RNA cell line specific nTPM":{"REH":"787.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051134","HPA071406"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"48000000000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA051134":"AB_2681356","HPA071406":"AB_2686393"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-6"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"70.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"25.2","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"4.8","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"24.7","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"14.3","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"787.7","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"17.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"6.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"12.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"14.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"78.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"140.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.4","Single Cell Type RNA - Melanocytes [nTPM]":"119.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"17.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"17.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"IKBKB","Gene synonym":["IKK-beta","IKK2","IKKB","NFKBIKB"],"Ensembl":"ENSG00000104365","Gene description":"Inhibitor of nuclear factor kappa B kinase subunit beta","Uniprot":["O14920"],"Chromosome":"8","Position":"42271302-42332460","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"135.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001249","CAB004447"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004447":"AB_627785","HPA001249":"AB_1079126"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.46e-6"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"8.2","Tissue RNA - amygdala [nTPM]":"9.1","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"9.8","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"8.3","Tissue RNA - cerebellum [nTPM]":"9.2","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"10.2","Tissue RNA - fallopian tube [nTPM]":"11.6","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"5.6","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"9.5","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"11.3","Tissue RNA - lymph node [nTPM]":"12.2","Tissue RNA - medulla oblongata [nTPM]":"10.5","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"6.2","Tissue RNA - parathyroid gland [nTPM]":"13.5","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"8.2","Tissue RNA - pons [nTPM]":"10.0","Tissue RNA - prostate [nTPM]":"7.9","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"13.7","Tissue RNA - skin 1 [nTPM]":"11.4","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"12.7","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"10.8","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"24.3","Tissue RNA - tonsil [nTPM]":"11.6","Tissue RNA - urinary bladder [nTPM]":"11.1","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"10.2","Cell RNA - A-431 [nTPM]":"6.2","Cell RNA - A549 [nTPM]":"15.7","Cell RNA - AF22 [nTPM]":"8.0","Cell RNA - AN3-CA [nTPM]":"13.6","Cell RNA - ASC diff [nTPM]":"17.3","Cell RNA - ASC TERT1 [nTPM]":"18.9","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"18.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.2","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"13.9","Cell RNA - Daudi [nTPM]":"14.1","Cell RNA - EFO-21 [nTPM]":"10.0","Cell RNA - fHDF\/TERT166 [nTPM]":"16.5","Cell RNA - GAMG [nTPM]":"12.5","Cell RNA - HaCaT [nTPM]":"5.6","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"18.3","Cell RNA - HBF TERT88 [nTPM]":"17.8","Cell RNA - HDLM-2 [nTPM]":"9.8","Cell RNA - HEK 293 [nTPM]":"10.8","Cell RNA - HEL [nTPM]":"17.8","Cell RNA - HeLa [nTPM]":"7.8","Cell RNA - Hep G2 [nTPM]":"5.9","Cell RNA - HHSteC [nTPM]":"20.9","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"24.0","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"13.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.0","Cell RNA - hTERT-HME1 [nTPM]":"19.1","Cell RNA - hTERT-RPE1 [nTPM]":"36.1","Cell RNA - HUVEC TERT2 [nTPM]":"20.7","Cell RNA - JURKAT [nTPM]":"11.6","Cell RNA - K-562 [nTPM]":"12.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"34.6","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"11.3","Cell RNA - NTERA-2 [nTPM]":"6.1","Cell RNA - OE19 [nTPM]":"18.9","Cell RNA - PC-3 [nTPM]":"6.0","Cell RNA - REH [nTPM]":"11.1","Cell RNA - RH-30 [nTPM]":"15.3","Cell RNA - RPMI-8226 [nTPM]":"10.0","Cell RNA - RPTEC TERT1 [nTPM]":"19.6","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"11.7","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"8.7","Cell RNA - THP-1 [nTPM]":"23.6","Cell RNA - TIME [nTPM]":"13.6","Cell RNA - U-138 MG [nTPM]":"7.2","Cell RNA - U-2 OS [nTPM]":"3.9","Cell RNA - U-2197 [nTPM]":"13.9","Cell RNA - U-251 MG [nTPM]":"6.1","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"4.0","Cell RNA - U-698 [nTPM]":"10.3","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"7.6","Cell RNA - WM-115 [nTPM]":"16.7","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"5.0","Blood RNA - eosinophil [nTPM]":"5.6","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"4.3","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"5.5","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"4.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"4.7","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"5.1","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"8.5","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"9.1","Brain RNA - basal ganglia [nTPM]":"9.8","Brain RNA - cerebellum [nTPM]":"9.2","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"9.5","Brain RNA - medulla oblongata [nTPM]":"10.5","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"10.0","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"10.2","Single Cell Type RNA - Adipocytes [nTPM]":"31.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.9","Single Cell Type RNA - Astrocytes [nTPM]":"19.2","Single Cell Type RNA - B-cells [nTPM]":"28.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"135.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - dendritic cells [nTPM]":"34.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.6","Single Cell Type RNA - Endothelial cells [nTPM]":"27.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.5","Single Cell Type RNA - granulocytes [nTPM]":"38.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"12.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.6","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"32.3","Single Cell Type RNA - Langerhans cells [nTPM]":"24.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"23.4","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"33.7","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.6","Single Cell Type RNA - Paneth cells [nTPM]":"15.0","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"18.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"7.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.1","Single Cell Type RNA - Urothelial cells [nTPM]":"30.8"},{"Gene":"IKBKG","Gene synonym":["FIP-3","FIP3","Fip3p","IKK-gamma","IP1","IP2","NEMO","ZC2HC9"],"Ensembl":"ENSG00000269335","Gene description":"Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma","Uniprot":["Q9Y6K9"],"Chromosome":"X","Position":"154541199-154565046","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["DNA damage","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Disease variant","Ectodermal dysplasia","Osteopetrosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000426","CAB010373"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB010373":"AB_2124846","HPA000426":"AB_1851572"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.4","Tissue RNA - adrenal gland [nTPM]":"32.1","Tissue RNA - amygdala [nTPM]":"18.0","Tissue RNA - appendix [nTPM]":"27.6","Tissue RNA - basal ganglia [nTPM]":"19.2","Tissue RNA - bone marrow [nTPM]":"42.5","Tissue RNA - breast [nTPM]":"21.7","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"23.8","Tissue RNA - cervix [nTPM]":"18.9","Tissue RNA - choroid plexus [nTPM]":"16.6","Tissue RNA - colon [nTPM]":"22.1","Tissue RNA - duodenum [nTPM]":"21.2","Tissue RNA - endometrium 1 [nTPM]":"24.3","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"25.5","Tissue RNA - fallopian tube [nTPM]":"19.4","Tissue RNA - gallbladder [nTPM]":"16.0","Tissue RNA - heart muscle [nTPM]":"21.5","Tissue RNA - hippocampal formation [nTPM]":"17.9","Tissue RNA - hypothalamus [nTPM]":"17.3","Tissue RNA - kidney [nTPM]":"20.7","Tissue RNA - liver [nTPM]":"62.5","Tissue RNA - lung [nTPM]":"29.7","Tissue RNA - lymph node [nTPM]":"29.0","Tissue RNA - medulla oblongata [nTPM]":"22.7","Tissue RNA - midbrain [nTPM]":"19.3","Tissue RNA - ovary [nTPM]":"18.3","Tissue RNA - pancreas [nTPM]":"18.7","Tissue RNA - parathyroid gland [nTPM]":"10.8","Tissue RNA - pituitary gland [nTPM]":"20.2","Tissue RNA - placenta [nTPM]":"11.9","Tissue RNA - pons [nTPM]":"21.6","Tissue RNA - prostate [nTPM]":"19.9","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"19.8","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"20.0","Tissue RNA - skin 1 [nTPM]":"28.4","Tissue RNA - small intestine [nTPM]":"26.6","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"17.9","Tissue RNA - spleen [nTPM]":"41.8","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"18.8","Tissue RNA - thalamus [nTPM]":"20.6","Tissue RNA - thymus [nTPM]":"19.7","Tissue RNA - thyroid gland [nTPM]":"22.9","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"18.7","Tissue RNA - urinary bladder [nTPM]":"24.8","Tissue RNA - vagina [nTPM]":"21.1","Tissue RNA - white matter [nTPM]":"23.6","Cell RNA - A-431 [nTPM]":"45.8","Cell RNA - A549 [nTPM]":"46.6","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"37.1","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"18.2","Cell RNA - BEWO [nTPM]":"29.7","Cell RNA - BJ [nTPM]":"28.2","Cell RNA - BJ hTERT+ [nTPM]":"35.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.9","Cell RNA - CACO-2 [nTPM]":"32.2","Cell RNA - CAPAN-2 [nTPM]":"26.5","Cell RNA - Daudi [nTPM]":"35.6","Cell RNA - EFO-21 [nTPM]":"73.5","Cell RNA - fHDF\/TERT166 [nTPM]":"32.6","Cell RNA - GAMG [nTPM]":"79.6","Cell RNA - HaCaT [nTPM]":"39.8","Cell RNA - HAP1 [nTPM]":"15.0","Cell RNA - HBEC3-KT [nTPM]":"27.3","Cell RNA - HBF TERT88 [nTPM]":"12.0","Cell RNA - HDLM-2 [nTPM]":"39.6","Cell RNA - HEK 293 [nTPM]":"25.2","Cell RNA - HEL [nTPM]":"27.5","Cell RNA - HeLa [nTPM]":"65.4","Cell RNA - Hep G2 [nTPM]":"54.9","Cell RNA - HHSteC [nTPM]":"37.4","Cell RNA - HL-60 [nTPM]":"29.3","Cell RNA - HMC-1 [nTPM]":"92.7","Cell RNA - HSkMC [nTPM]":"23.4","Cell RNA - hTCEpi [nTPM]":"25.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.9","Cell RNA - hTERT-HME1 [nTPM]":"15.8","Cell RNA - hTERT-RPE1 [nTPM]":"19.4","Cell RNA - HUVEC TERT2 [nTPM]":"33.2","Cell RNA - JURKAT [nTPM]":"34.6","Cell RNA - K-562 [nTPM]":"16.6","Cell RNA - Karpas-707 [nTPM]":"34.3","Cell RNA - LHCN-M2 [nTPM]":"23.5","Cell RNA - MCF7 [nTPM]":"43.1","Cell RNA - MOLT-4 [nTPM]":"29.7","Cell RNA - NB-4 [nTPM]":"52.9","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"32.5","Cell RNA - PC-3 [nTPM]":"69.2","Cell RNA - REH [nTPM]":"35.4","Cell RNA - RH-30 [nTPM]":"16.7","Cell RNA - RPMI-8226 [nTPM]":"38.4","Cell RNA - RPTEC TERT1 [nTPM]":"27.6","Cell RNA - RT4 [nTPM]":"27.4","Cell RNA - SCLC-21H [nTPM]":"19.5","Cell RNA - SH-SY5Y [nTPM]":"19.9","Cell RNA - SiHa [nTPM]":"32.7","Cell RNA - SK-BR-3 [nTPM]":"32.9","Cell RNA - SK-MEL-30 [nTPM]":"23.0","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"19.4","Cell RNA - THP-1 [nTPM]":"33.4","Cell RNA - TIME [nTPM]":"36.4","Cell RNA - U-138 MG [nTPM]":"29.8","Cell RNA - U-2 OS [nTPM]":"33.9","Cell RNA - U-2197 [nTPM]":"70.6","Cell RNA - U-251 MG [nTPM]":"69.9","Cell RNA - U-266\/70 [nTPM]":"67.5","Cell RNA - U-266\/84 [nTPM]":"49.0","Cell RNA - U-698 [nTPM]":"69.2","Cell RNA - U-87 MG [nTPM]":"41.4","Cell RNA - U-937 [nTPM]":"50.6","Cell RNA - WM-115 [nTPM]":"41.3","Blood RNA - basophil [nTPM]":"24.9","Blood RNA - classical monocyte [nTPM]":"34.2","Blood RNA - eosinophil [nTPM]":"61.3","Blood RNA - gdT-cell [nTPM]":"35.3","Blood RNA - intermediate monocyte [nTPM]":"42.2","Blood RNA - MAIT T-cell [nTPM]":"24.1","Blood RNA - memory B-cell [nTPM]":"21.3","Blood RNA - memory CD4 T-cell [nTPM]":"21.4","Blood RNA - memory CD8 T-cell [nTPM]":"26.5","Blood RNA - myeloid DC [nTPM]":"29.8","Blood RNA - naive B-cell [nTPM]":"20.9","Blood RNA - naive CD4 T-cell [nTPM]":"17.1","Blood RNA - naive CD8 T-cell [nTPM]":"21.3","Blood RNA - neutrophil [nTPM]":"50.4","Blood RNA - NK-cell [nTPM]":"30.7","Blood RNA - non-classical monocyte [nTPM]":"51.1","Blood RNA - plasmacytoid DC [nTPM]":"25.4","Blood RNA - T-reg [nTPM]":"26.8","Blood RNA - total PBMC [nTPM]":"31.0","Brain RNA - amygdala [nTPM]":"18.0","Brain RNA - basal ganglia [nTPM]":"19.2","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"23.8","Brain RNA - hippocampal formation [nTPM]":"17.9","Brain RNA - hypothalamus [nTPM]":"17.3","Brain RNA - medulla oblongata [nTPM]":"22.7","Brain RNA - midbrain [nTPM]":"19.3","Brain RNA - pons [nTPM]":"21.6","Brain RNA - spinal cord [nTPM]":"17.9","Brain RNA - thalamus [nTPM]":"20.6","Brain RNA - white matter [nTPM]":"23.6","Single Cell Type RNA - Adipocytes [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"22.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"13.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.3","Single Cell Type RNA - dendritic cells [nTPM]":"27.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"15.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.5","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"12.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"36.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.3","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"15.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"14.3","Single Cell Type RNA - Macrophages [nTPM]":"29.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"44.5","Single Cell Type RNA - Muller glia cells [nTPM]":"11.1","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.4","Single Cell Type RNA - Paneth cells [nTPM]":"12.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.6","Single Cell Type RNA - Spermatogonia [nTPM]":"12.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"24.6","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"14.2"},{"Gene":"IKZF1","Gene synonym":["hIk-1","Hs.54452","IKAROS","LyF-1","PPP1R92","ZNFN1A1"],"Ensembl":"ENSG00000185811","Gene description":"IKAROS family zinc finger 1","Uniprot":["Q13422"],"Chromosome":"7","Position":"50304068-50405101","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Cell cycle","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"173.0","lymphoid tissue":"112.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"120.5","dendritic cells":"221.4","Erythroid cells":"89.8","Microglial cells":"91.8","monocytes":"106.6","NK-cells":"150.4","Plasma cells":"128.9","T-cells":"182.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"140.4","HDLM-2":"258.6","HMC-1":"220.4","JURKAT":"128.9","MOLT-4":"184.3","REH":"192.3","U-698":"342.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009247","HPA035221","HPA035222"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB009247":"AB_2124699","HPA035221":"AB_2674524","HPA035222":"AB_2674525"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.28e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.02e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"53.0","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"173.0","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"3.6","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"4.9","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"87.1","Tissue RNA - medulla oblongata [nTPM]":"7.7","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"48.6","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"112.5","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"73.8","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"140.4","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"258.6","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"52.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"84.5","Cell RNA - HMC-1 [nTPM]":"220.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"128.9","Cell RNA - K-562 [nTPM]":"72.4","Cell RNA - Karpas-707 [nTPM]":"15.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"184.3","Cell RNA - NB-4 [nTPM]":"80.9","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"192.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"39.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"112.1","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"80.8","Cell RNA - U-266\/84 [nTPM]":"49.4","Cell RNA - U-698 [nTPM]":"342.7","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"89.5","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"21.2","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"25.0","Blood RNA - gdT-cell [nTPM]":"35.4","Blood RNA - intermediate monocyte [nTPM]":"43.9","Blood RNA - MAIT T-cell [nTPM]":"29.1","Blood RNA - memory B-cell [nTPM]":"46.7","Blood RNA - memory CD4 T-cell [nTPM]":"36.3","Blood RNA - memory CD8 T-cell [nTPM]":"35.0","Blood RNA - myeloid DC [nTPM]":"15.1","Blood RNA - naive B-cell [nTPM]":"40.7","Blood RNA - naive CD4 T-cell [nTPM]":"48.2","Blood RNA - naive CD8 T-cell [nTPM]":"35.7","Blood RNA - neutrophil [nTPM]":"20.2","Blood RNA - NK-cell [nTPM]":"24.3","Blood RNA - non-classical monocyte [nTPM]":"43.3","Blood RNA - plasmacytoid DC [nTPM]":"23.4","Blood RNA - T-reg [nTPM]":"32.6","Blood RNA - total PBMC [nTPM]":"26.4","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"7.7","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"120.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"221.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"89.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"2.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"64.3","Single Cell Type RNA - Langerhans cells [nTPM]":"61.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"72.1","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"91.8","Single Cell Type RNA - monocytes [nTPM]":"106.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"150.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"128.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"182.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"IL12B","Gene synonym":["CLMF","CLMF2","IL-12B","NKSF","NKSF2"],"Ensembl":"ENSG00000113302","Gene description":"Interleukin 12B","Uniprot":["P29460"],"Chromosome":"5","Position":"159314780-159330487","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"monocytes":"6.7"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"20","RNA cancer specific FPKM":{"testis cancer":"3.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SCLC-21H":"1.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040970"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":140000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 7: SCLC-21H - Neuronal signaling","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040970":"AB_10796234"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.5","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"1.4","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IL12RB1","Gene synonym":["CD212","IL12RB"],"Ensembl":"ENSG00000096996","Gene description":"Interleukin 12 receptor subunit beta 1","Uniprot":["P42701"],"Chromosome":"19","Position":"18058995-18098944","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"24.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"35.1","Kupffer cells":"13.9","NK-cells":"69.0","Plasma cells":"15.3","T-cells":"31.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"18.8","HDLM-2":"35.2","Karpas-707":"57.8","U-698":"15.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074414"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA074414":"AB_2686687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.41e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.90e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"15.2","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"4.5","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"1.6","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"3.5","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"24.6","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"0.8","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"14.1","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"18.8","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"35.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"3.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"57.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"9.7","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"6.7","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"9.7","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"6.6","Cell RNA - U-266\/84 [nTPM]":"11.0","Cell RNA - U-698 [nTPM]":"15.2","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"12.1","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"8.5","Blood RNA - classical monocyte [nTPM]":"12.5","Blood RNA - eosinophil [nTPM]":"9.2","Blood RNA - gdT-cell [nTPM]":"50.9","Blood RNA - intermediate monocyte [nTPM]":"34.7","Blood RNA - MAIT T-cell [nTPM]":"64.0","Blood RNA - memory B-cell [nTPM]":"11.5","Blood RNA - memory CD4 T-cell [nTPM]":"34.8","Blood RNA - memory CD8 T-cell [nTPM]":"41.7","Blood RNA - myeloid DC [nTPM]":"14.7","Blood RNA - naive B-cell [nTPM]":"9.1","Blood RNA - naive CD4 T-cell [nTPM]":"19.3","Blood RNA - naive CD8 T-cell [nTPM]":"34.0","Blood RNA - neutrophil [nTPM]":"14.7","Blood RNA - NK-cell [nTPM]":"40.9","Blood RNA - non-classical monocyte [nTPM]":"34.0","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"53.0","Blood RNA - total PBMC [nTPM]":"24.3","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"35.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"13.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"11.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"11.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"69.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"15.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"31.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"IL21","Gene synonym":["IL-21","Za11"],"Ensembl":"ENSG00000138684","Gene description":"Interleukin 21","Uniprot":["Q9HBE4"],"Chromosome":"4","Position":"122610108-122621066","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"lymphoid tissue":"5.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"18","RNA single cell type specific nTPM":{"Early spermatids":"13.7","Late spermatids":"8.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":55700,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"13.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IL2RA","Gene synonym":["CD25","IDDM10","IL2R"],"Ensembl":"ENSG00000134460","Gene description":"Interleukin 2 receptor subunit alpha","Uniprot":["P01589"],"Chromosome":"10","Position":"6010689-6062370","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"18.9","lymphoid tissue":"17.4","urinary bladder":"11.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"granulocytes":"80.8","monocytes":"177.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"basophil":"175.9","T-reg":"248.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"granulocytes":"175.9","T-cells":"248.0"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"59","RNA cell line specific nTPM":{"HDLM-2":"1113.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002419","HPA054622"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"410000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002419":"AB_563538","HPA054622":"AB_2682546"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"14.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.4","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"2.9","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.7","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"6.5","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"7.5","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"11.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1113.3","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"18.9","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"175.9","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"20.1","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"14.7","Blood RNA - memory CD4 T-cell [nTPM]":"27.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"7.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"13.4","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"248.0","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"8.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"80.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"177.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"19.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"IL2RG","Gene synonym":["CD132","CIDX","IMD4","SCIDX1"],"Ensembl":"ENSG00000147168","Gene description":"Interleukin 2 receptor subunit gamma","Uniprot":["P31785"],"Chromosome":"X","Position":"71107404-71112108","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"118.0","lymphoid tissue":"346.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"186.1","dendritic cells":"199.0","Distal enterocytes":"202.0","NK-cells":"310.0","Paneth cells":"133.2","Plasma cells":"221.2","T-cells":"289.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Karpas-707":"2316.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046641","HPA049691"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 58: T-cells - T-cell receptor","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046641":"AB_2679733","HPA049691":"AB_2680851"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.28e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"132.2","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"87.3","Tissue RNA - breast [nTPM]":"14.1","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"10.2","Tissue RNA - choroid plexus [nTPM]":"4.0","Tissue RNA - colon [nTPM]":"98.9","Tissue RNA - duodenum [nTPM]":"50.4","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"6.8","Tissue RNA - gallbladder [nTPM]":"28.2","Tissue RNA - heart muscle [nTPM]":"4.6","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"20.6","Tissue RNA - lung [nTPM]":"51.7","Tissue RNA - lymph node [nTPM]":"235.6","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"4.9","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"16.9","Tissue RNA - pons [nTPM]":"4.2","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"118.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"19.0","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"15.4","Tissue RNA - small intestine [nTPM]":"82.8","Tissue RNA - smooth muscle [nTPM]":"12.3","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"119.4","Tissue RNA - stomach 1 [nTPM]":"41.4","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"3.0","Tissue RNA - thymus [nTPM]":"346.4","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"306.9","Tissue RNA - urinary bladder [nTPM]":"46.4","Tissue RNA - vagina [nTPM]":"5.5","Tissue RNA - white matter [nTPM]":"3.8","Cell RNA - A-431 [nTPM]":"1.2","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"4.7","Cell RNA - CAPAN-2 [nTPM]":"9.1","Cell RNA - Daudi [nTPM]":"187.3","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"160.3","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"23.6","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"99.3","Cell RNA - HMC-1 [nTPM]":"4.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"220.5","Cell RNA - K-562 [nTPM]":"43.3","Cell RNA - Karpas-707 [nTPM]":"2316.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"356.4","Cell RNA - NB-4 [nTPM]":"193.7","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"79.5","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"20.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"132.1","Cell RNA - U-266\/84 [nTPM]":"242.2","Cell RNA - U-698 [nTPM]":"119.6","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"397.4","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"540.5","Blood RNA - classical monocyte [nTPM]":"102.2","Blood RNA - eosinophil [nTPM]":"169.7","Blood RNA - gdT-cell [nTPM]":"1204.7","Blood RNA - intermediate monocyte [nTPM]":"239.5","Blood RNA - MAIT T-cell [nTPM]":"1179.9","Blood RNA - memory B-cell [nTPM]":"604.7","Blood RNA - memory CD4 T-cell [nTPM]":"1086.3","Blood RNA - memory CD8 T-cell [nTPM]":"1250.7","Blood RNA - myeloid DC [nTPM]":"243.5","Blood RNA - naive B-cell [nTPM]":"603.0","Blood RNA - naive CD4 T-cell [nTPM]":"742.0","Blood RNA - naive CD8 T-cell [nTPM]":"943.1","Blood RNA - neutrophil [nTPM]":"773.0","Blood RNA - NK-cell [nTPM]":"1190.3","Blood RNA - non-classical monocyte [nTPM]":"177.0","Blood RNA - plasmacytoid DC [nTPM]":"368.9","Blood RNA - T-reg [nTPM]":"1422.2","Blood RNA - total PBMC [nTPM]":"1494.0","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"4.2","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"3.0","Brain RNA - white matter [nTPM]":"3.8","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"186.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"199.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"202.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"77.7","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"39.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"25.2","Single Cell Type RNA - Langerhans cells [nTPM]":"116.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"45.4","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"91.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"310.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.0","Single Cell Type RNA - Paneth cells [nTPM]":"133.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"221.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"88.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"289.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"IL6ST","Gene synonym":["CD130","GP130","sGP130"],"Ensembl":"ENSG00000134352","Gene description":"Interleukin 6 signal transducer","Uniprot":["P40189"],"Chromosome":"5","Position":"55935095-55995022","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"580.3","Hepatic stellate cells":"808.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"16.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"16.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"151.3","BJ hTERT+":"175.2","HHSteC":"155.1","HSkMC":"135.1","TIME":"147.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010558","CAB025784"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB025784":null,"HPA010558":"AB_1078439"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"67.1","Tissue RNA - adrenal gland [nTPM]":"46.0","Tissue RNA - amygdala [nTPM]":"26.8","Tissue RNA - appendix [nTPM]":"14.1","Tissue RNA - basal ganglia [nTPM]":"31.0","Tissue RNA - bone marrow [nTPM]":"9.6","Tissue RNA - breast [nTPM]":"51.3","Tissue RNA - cerebellum [nTPM]":"30.9","Tissue RNA - cerebral cortex [nTPM]":"36.7","Tissue RNA - cervix [nTPM]":"43.0","Tissue RNA - choroid plexus [nTPM]":"21.3","Tissue RNA - colon [nTPM]":"33.9","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"35.2","Tissue RNA - epididymis [nTPM]":"18.5","Tissue RNA - esophagus [nTPM]":"18.4","Tissue RNA - fallopian tube [nTPM]":"34.2","Tissue RNA - gallbladder [nTPM]":"23.6","Tissue RNA - heart muscle [nTPM]":"35.1","Tissue RNA - hippocampal formation [nTPM]":"23.5","Tissue RNA - hypothalamus [nTPM]":"31.4","Tissue RNA - kidney [nTPM]":"30.0","Tissue RNA - liver [nTPM]":"77.6","Tissue RNA - lung [nTPM]":"53.3","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"32.1","Tissue RNA - midbrain [nTPM]":"27.0","Tissue RNA - ovary [nTPM]":"36.9","Tissue RNA - pancreas [nTPM]":"21.9","Tissue RNA - parathyroid gland [nTPM]":"39.6","Tissue RNA - pituitary gland [nTPM]":"22.5","Tissue RNA - placenta [nTPM]":"101.7","Tissue RNA - pons [nTPM]":"35.9","Tissue RNA - prostate [nTPM]":"32.6","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"28.6","Tissue RNA - salivary gland [nTPM]":"31.9","Tissue RNA - seminal vesicle [nTPM]":"29.9","Tissue RNA - skeletal muscle [nTPM]":"41.0","Tissue RNA - skin 1 [nTPM]":"17.8","Tissue RNA - small intestine [nTPM]":"31.1","Tissue RNA - smooth muscle [nTPM]":"28.7","Tissue RNA - spinal cord [nTPM]":"35.1","Tissue RNA - spleen [nTPM]":"34.7","Tissue RNA - stomach 1 [nTPM]":"27.8","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"25.3","Tissue RNA - thymus [nTPM]":"23.6","Tissue RNA - thyroid gland [nTPM]":"40.4","Tissue RNA - tongue [nTPM]":"34.7","Tissue RNA - tonsil [nTPM]":"16.2","Tissue RNA - urinary bladder [nTPM]":"37.7","Tissue RNA - vagina [nTPM]":"35.1","Tissue RNA - white matter [nTPM]":"42.9","Cell RNA - A-431 [nTPM]":"14.4","Cell RNA - A549 [nTPM]":"35.6","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"18.8","Cell RNA - ASC diff [nTPM]":"75.5","Cell RNA - ASC TERT1 [nTPM]":"151.3","Cell RNA - BEWO [nTPM]":"22.3","Cell RNA - BJ [nTPM]":"54.5","Cell RNA - BJ hTERT+ [nTPM]":"175.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.4","Cell RNA - CACO-2 [nTPM]":"40.5","Cell RNA - CAPAN-2 [nTPM]":"16.3","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"33.7","Cell RNA - fHDF\/TERT166 [nTPM]":"52.5","Cell RNA - GAMG [nTPM]":"71.6","Cell RNA - HaCaT [nTPM]":"7.8","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"84.1","Cell RNA - HDLM-2 [nTPM]":"1.6","Cell RNA - HEK 293 [nTPM]":"8.5","Cell RNA - HEL [nTPM]":"4.6","Cell RNA - HeLa [nTPM]":"20.1","Cell RNA - Hep G2 [nTPM]":"14.2","Cell RNA - HHSteC [nTPM]":"155.1","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"6.2","Cell RNA - HSkMC [nTPM]":"135.1","Cell RNA - hTCEpi [nTPM]":"11.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"103.1","Cell RNA - hTERT-HME1 [nTPM]":"42.7","Cell RNA - hTERT-RPE1 [nTPM]":"43.6","Cell RNA - HUVEC TERT2 [nTPM]":"101.8","Cell RNA - JURKAT [nTPM]":"1.9","Cell RNA - K-562 [nTPM]":"3.7","Cell RNA - Karpas-707 [nTPM]":"51.0","Cell RNA - LHCN-M2 [nTPM]":"47.0","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"1.8","Cell RNA - PC-3 [nTPM]":"10.1","Cell RNA - REH [nTPM]":"1.1","Cell RNA - RH-30 [nTPM]":"22.5","Cell RNA - RPMI-8226 [nTPM]":"14.4","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"3.8","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"26.6","Cell RNA - SK-BR-3 [nTPM]":"5.7","Cell RNA - SK-MEL-30 [nTPM]":"19.7","Cell RNA - SuSa [nTPM]":"13.7","Cell RNA - T-47d [nTPM]":"29.5","Cell RNA - THP-1 [nTPM]":"3.1","Cell RNA - TIME [nTPM]":"147.8","Cell RNA - U-138 MG [nTPM]":"12.4","Cell RNA - U-2 OS [nTPM]":"10.1","Cell RNA - U-2197 [nTPM]":"44.5","Cell RNA - U-251 MG [nTPM]":"24.6","Cell RNA - U-266\/70 [nTPM]":"14.6","Cell RNA - U-266\/84 [nTPM]":"8.2","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"28.9","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"31.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"16.7","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"26.8","Brain RNA - basal ganglia [nTPM]":"31.0","Brain RNA - cerebellum [nTPM]":"30.9","Brain RNA - cerebral cortex [nTPM]":"36.7","Brain RNA - hippocampal formation [nTPM]":"23.5","Brain RNA - hypothalamus [nTPM]":"31.4","Brain RNA - medulla oblongata [nTPM]":"32.1","Brain RNA - midbrain [nTPM]":"27.0","Brain RNA - pons [nTPM]":"35.9","Brain RNA - spinal cord [nTPM]":"35.1","Brain RNA - thalamus [nTPM]":"25.3","Brain RNA - white matter [nTPM]":"42.9","Single Cell Type RNA - Adipocytes [nTPM]":"221.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"134.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"149.8","Single Cell Type RNA - Astrocytes [nTPM]":"59.4","Single Cell Type RNA - B-cells [nTPM]":"30.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"103.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"98.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"60.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"71.2","Single Cell Type RNA - Bipolar cells [nTPM]":"56.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"202.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"81.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"81.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"124.4","Single Cell Type RNA - Club cells [nTPM]":"105.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"77.9","Single Cell Type RNA - dendritic cells [nTPM]":"33.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"85.3","Single Cell Type RNA - Early spermatids [nTPM]":"12.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"76.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"227.6","Single Cell Type RNA - Endothelial cells [nTPM]":"256.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"41.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"62.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"75.5","Single Cell Type RNA - Fibroblasts [nTPM]":"285.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"59.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"580.3","Single Cell Type RNA - granulocytes [nTPM]":"32.9","Single Cell Type RNA - Granulosa cells [nTPM]":"58.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"808.5","Single Cell Type RNA - Hepatocytes [nTPM]":"219.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"56.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"70.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.1","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"93.7","Single Cell Type RNA - Langerhans cells [nTPM]":"99.1","Single Cell Type RNA - Late spermatids [nTPM]":"16.7","Single Cell Type RNA - Leydig cells [nTPM]":"105.9","Single Cell Type RNA - Macrophages [nTPM]":"60.3","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"188.3","Single Cell Type RNA - monocytes [nTPM]":"45.8","Single Cell Type RNA - Muller glia cells [nTPM]":"190.8","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"75.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"80.8","Single Cell Type RNA - Paneth cells [nTPM]":"35.6","Single Cell Type RNA - Peritubular cells [nTPM]":"130.5","Single Cell Type RNA - Plasma cells [nTPM]":"100.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"163.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"80.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.3","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"158.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"150.3","Single Cell Type RNA - Spermatocytes [nTPM]":"54.4","Single Cell Type RNA - Spermatogonia [nTPM]":"38.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"44.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"83.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"101.8","Single Cell Type RNA - T-cells [nTPM]":"75.5","Single Cell Type RNA - Theca cells [nTPM]":"228.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.1","Single Cell Type RNA - Urothelial cells [nTPM]":"106.1"},{"Gene":"IL7R","Gene synonym":["CD127","IL7RA"],"Ensembl":"ENSG00000168685","Gene description":"Interleukin 7 receptor","Uniprot":["P16871"],"Chromosome":"5","Position":"35852695-35879603","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"183.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"monocytes":"271.8","T-cells":"973.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"102.1","MAIT T-cell":"369.5","memory CD4 T-cell":"213.8","memory CD8 T-cell":"151.1","naive CD4 T-cell":"179.5","naive CD8 T-cell":"124.6","NK-cell":"113.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"33","RNA blood lineage specific nTPM":{"NK-cells":"113.2","T-cells":"369.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"99.8","BJ hTERT+ SV40 Large T+":"87.7","fHDF\/TERT166":"187.7","HBF TERT88":"168.3","REH":"406.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010215","HPA067550"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"610000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010215":"AB_673727","HPA067550":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.2","Tissue RNA - adrenal gland [nTPM]":"14.4","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"137.6","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"14.0","Tissue RNA - breast [nTPM]":"20.4","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"17.3","Tissue RNA - duodenum [nTPM]":"15.0","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"11.0","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"32.4","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"12.5","Tissue RNA - lung [nTPM]":"63.9","Tissue RNA - lymph node [nTPM]":"139.4","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"2.9","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"8.7","Tissue RNA - rectum [nTPM]":"20.4","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"3.8","Tissue RNA - small intestine [nTPM]":"56.8","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"70.1","Tissue RNA - stomach 1 [nTPM]":"34.1","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"183.7","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"123.0","Tissue RNA - urinary bladder [nTPM]":"48.0","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"99.8","Cell RNA - BJ hTERT+ [nTPM]":"50.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.3","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"9.6","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"187.7","Cell RNA - GAMG [nTPM]":"15.9","Cell RNA - HaCaT [nTPM]":"16.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"6.0","Cell RNA - HBF TERT88 [nTPM]":"168.3","Cell RNA - HDLM-2 [nTPM]":"8.6","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"3.2","Cell RNA - HeLa [nTPM]":"10.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"7.2","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.7","Cell RNA - hTERT-HME1 [nTPM]":"4.3","Cell RNA - hTERT-RPE1 [nTPM]":"2.4","Cell RNA - HUVEC TERT2 [nTPM]":"2.6","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"71.3","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"4.6","Cell RNA - REH [nTPM]":"406.2","Cell RNA - RH-30 [nTPM]":"5.2","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"5.3","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"15.9","Cell RNA - SK-BR-3 [nTPM]":"1.7","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"7.0","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"58.4","Cell RNA - U-2197 [nTPM]":"14.8","Cell RNA - U-251 MG [nTPM]":"13.4","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"10.4","Cell RNA - U-87 MG [nTPM]":"17.4","Cell RNA - U-937 [nTPM]":"9.2","Cell RNA - WM-115 [nTPM]":"27.8","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"102.1","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"369.5","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"213.8","Blood RNA - memory CD8 T-cell [nTPM]":"151.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"179.5","Blood RNA - naive CD8 T-cell [nTPM]":"124.6","Blood RNA - neutrophil [nTPM]":"7.3","Blood RNA - NK-cell [nTPM]":"113.2","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"39.7","Blood RNA - total PBMC [nTPM]":"87.7","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"8.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"47.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"136.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"11.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"4.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"10.6","Single Cell Type RNA - Langerhans cells [nTPM]":"98.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"58.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"271.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"93.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"973.8","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"IRAK4","Gene synonym":["NY-REN-64"],"Ensembl":"ENSG00000198001","Gene description":"Interleukin 1 receptor associated kinase 4","Uniprot":["Q9NWZ3"],"Chromosome":"12","Position":"43758944-43789543","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-937":"56.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016685","CAB022077"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Microtubules","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Microtubules"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"CAB016685":"AB_1618505","CAB022077":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.46e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.42e-5"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"6.5","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"13.6","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"10.0","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"5.1","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"7.9","Tissue RNA - duodenum [nTPM]":"9.1","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"7.0","Tissue RNA - esophagus [nTPM]":"10.5","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"5.6","Tissue RNA - pancreas [nTPM]":"15.1","Tissue RNA - parathyroid gland [nTPM]":"6.9","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"7.5","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"13.3","Tissue RNA - small intestine [nTPM]":"11.9","Tissue RNA - smooth muscle [nTPM]":"7.2","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"5.8","Tissue RNA - thalamus [nTPM]":"4.9","Tissue RNA - thymus [nTPM]":"18.5","Tissue RNA - thyroid gland [nTPM]":"10.9","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"16.3","Tissue RNA - urinary bladder [nTPM]":"7.8","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"5.3","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"4.7","Cell RNA - AN3-CA [nTPM]":"6.2","Cell RNA - ASC diff [nTPM]":"16.5","Cell RNA - ASC TERT1 [nTPM]":"27.6","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"12.9","Cell RNA - BJ hTERT+ [nTPM]":"9.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"8.7","Cell RNA - Daudi [nTPM]":"15.8","Cell RNA - EFO-21 [nTPM]":"12.4","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"6.6","Cell RNA - HaCaT [nTPM]":"7.5","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"8.3","Cell RNA - HBF TERT88 [nTPM]":"14.2","Cell RNA - HDLM-2 [nTPM]":"22.8","Cell RNA - HEK 293 [nTPM]":"4.9","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"21.2","Cell RNA - HMC-1 [nTPM]":"17.7","Cell RNA - HSkMC [nTPM]":"14.7","Cell RNA - hTCEpi [nTPM]":"12.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.7","Cell RNA - hTERT-HME1 [nTPM]":"7.4","Cell RNA - hTERT-RPE1 [nTPM]":"17.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.0","Cell RNA - JURKAT [nTPM]":"15.1","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"11.6","Cell RNA - LHCN-M2 [nTPM]":"27.8","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"18.6","Cell RNA - NB-4 [nTPM]":"11.7","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"12.2","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"8.8","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"6.3","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"6.2","Cell RNA - SuSa [nTPM]":"6.4","Cell RNA - T-47d [nTPM]":"9.9","Cell RNA - THP-1 [nTPM]":"18.5","Cell RNA - TIME [nTPM]":"13.4","Cell RNA - U-138 MG [nTPM]":"12.2","Cell RNA - U-2 OS [nTPM]":"2.3","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"14.0","Cell RNA - U-266\/84 [nTPM]":"19.4","Cell RNA - U-698 [nTPM]":"13.7","Cell RNA - U-87 MG [nTPM]":"12.7","Cell RNA - U-937 [nTPM]":"56.2","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"20.8","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"4.6","Blood RNA - MAIT T-cell [nTPM]":"6.3","Blood RNA - memory B-cell [nTPM]":"3.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.9","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"4.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.8","Blood RNA - neutrophil [nTPM]":"7.9","Blood RNA - NK-cell [nTPM]":"7.9","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"5.1","Blood RNA - T-reg [nTPM]":"6.7","Blood RNA - total PBMC [nTPM]":"4.6","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"5.1","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"4.9","Brain RNA - white matter [nTPM]":"5.3","Single Cell Type RNA - Adipocytes [nTPM]":"24.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"36.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"11.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.9","Single Cell Type RNA - dendritic cells [nTPM]":"52.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"12.7","Single Cell Type RNA - Early spermatids [nTPM]":"18.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.4","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.4","Single Cell Type RNA - Fibroblasts [nTPM]":"13.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"8.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.9","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"24.7","Single Cell Type RNA - Langerhans cells [nTPM]":"20.2","Single Cell Type RNA - Late spermatids [nTPM]":"23.2","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"25.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"28.2","Single Cell Type RNA - Muller glia cells [nTPM]":"9.9","Single Cell Type RNA - NK-cells [nTPM]":"60.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"28.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"41.1","Single Cell Type RNA - Theca cells [nTPM]":"15.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.2","Single Cell Type RNA - Urothelial cells [nTPM]":"13.5"},{"Gene":"IRF2BP2","Gene synonym":["IRF-2BP2"],"Ensembl":"ENSG00000168264","Gene description":"Interferon regulatory factor 2 binding protein 2","Uniprot":["Q7Z5L9"],"Chromosome":"1","Position":"234604269-234610178","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Repressor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"440.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"THP-1":"277.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027815","HPA062269"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"13000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA027815":"AB_10609994","HPA062269":"AB_2684732"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"35.6","Tissue RNA - adrenal gland [nTPM]":"39.6","Tissue RNA - amygdala [nTPM]":"43.3","Tissue RNA - appendix [nTPM]":"25.6","Tissue RNA - basal ganglia [nTPM]":"50.2","Tissue RNA - bone marrow [nTPM]":"157.2","Tissue RNA - breast [nTPM]":"45.0","Tissue RNA - cerebellum [nTPM]":"48.5","Tissue RNA - cerebral cortex [nTPM]":"49.1","Tissue RNA - cervix [nTPM]":"50.0","Tissue RNA - choroid plexus [nTPM]":"43.3","Tissue RNA - colon [nTPM]":"42.5","Tissue RNA - duodenum [nTPM]":"39.6","Tissue RNA - endometrium 1 [nTPM]":"55.8","Tissue RNA - epididymis [nTPM]":"26.5","Tissue RNA - esophagus [nTPM]":"47.0","Tissue RNA - fallopian tube [nTPM]":"45.1","Tissue RNA - gallbladder [nTPM]":"40.7","Tissue RNA - heart muscle [nTPM]":"45.0","Tissue RNA - hippocampal formation [nTPM]":"40.5","Tissue RNA - hypothalamus [nTPM]":"45.4","Tissue RNA - kidney [nTPM]":"34.2","Tissue RNA - liver [nTPM]":"53.6","Tissue RNA - lung [nTPM]":"43.7","Tissue RNA - lymph node [nTPM]":"36.3","Tissue RNA - medulla oblongata [nTPM]":"55.2","Tissue RNA - midbrain [nTPM]":"49.0","Tissue RNA - ovary [nTPM]":"54.8","Tissue RNA - pancreas [nTPM]":"49.5","Tissue RNA - parathyroid gland [nTPM]":"45.5","Tissue RNA - pituitary gland [nTPM]":"24.1","Tissue RNA - placenta [nTPM]":"29.6","Tissue RNA - pons [nTPM]":"51.1","Tissue RNA - prostate [nTPM]":"39.2","Tissue RNA - rectum [nTPM]":"49.3","Tissue RNA - retina [nTPM]":"26.9","Tissue RNA - salivary gland [nTPM]":"55.0","Tissue RNA - seminal vesicle [nTPM]":"33.5","Tissue RNA - skeletal muscle [nTPM]":"47.4","Tissue RNA - skin 1 [nTPM]":"64.2","Tissue RNA - small intestine [nTPM]":"42.2","Tissue RNA - smooth muscle [nTPM]":"31.7","Tissue RNA - spinal cord [nTPM]":"48.9","Tissue RNA - spleen [nTPM]":"28.4","Tissue RNA - stomach 1 [nTPM]":"44.4","Tissue RNA - testis [nTPM]":"18.0","Tissue RNA - thalamus [nTPM]":"44.7","Tissue RNA - thymus [nTPM]":"29.6","Tissue RNA - thyroid gland [nTPM]":"57.3","Tissue RNA - tongue [nTPM]":"40.5","Tissue RNA - tonsil [nTPM]":"30.3","Tissue RNA - urinary bladder [nTPM]":"38.7","Tissue RNA - vagina [nTPM]":"43.7","Tissue RNA - white matter [nTPM]":"61.1","Cell RNA - A-431 [nTPM]":"28.0","Cell RNA - A549 [nTPM]":"41.5","Cell RNA - AF22 [nTPM]":"29.8","Cell RNA - AN3-CA [nTPM]":"45.7","Cell RNA - ASC diff [nTPM]":"61.2","Cell RNA - ASC TERT1 [nTPM]":"48.1","Cell RNA - BEWO [nTPM]":"35.1","Cell RNA - BJ [nTPM]":"21.8","Cell RNA - BJ hTERT+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.2","Cell RNA - CACO-2 [nTPM]":"24.5","Cell RNA - CAPAN-2 [nTPM]":"33.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"49.4","Cell RNA - fHDF\/TERT166 [nTPM]":"21.2","Cell RNA - GAMG [nTPM]":"43.3","Cell RNA - HaCaT [nTPM]":"37.4","Cell RNA - HAP1 [nTPM]":"16.2","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"20.2","Cell RNA - HDLM-2 [nTPM]":"45.2","Cell RNA - HEK 293 [nTPM]":"36.8","Cell RNA - HEL [nTPM]":"26.7","Cell RNA - HeLa [nTPM]":"32.9","Cell RNA - Hep G2 [nTPM]":"72.3","Cell RNA - HHSteC [nTPM]":"49.4","Cell RNA - HL-60 [nTPM]":"101.0","Cell RNA - HMC-1 [nTPM]":"91.0","Cell RNA - HSkMC [nTPM]":"57.0","Cell RNA - hTCEpi [nTPM]":"65.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.3","Cell RNA - hTERT-HME1 [nTPM]":"53.4","Cell RNA - hTERT-RPE1 [nTPM]":"74.4","Cell RNA - HUVEC TERT2 [nTPM]":"33.0","Cell RNA - JURKAT [nTPM]":"24.5","Cell RNA - K-562 [nTPM]":"23.0","Cell RNA - Karpas-707 [nTPM]":"55.6","Cell RNA - LHCN-M2 [nTPM]":"33.2","Cell RNA - MCF7 [nTPM]":"8.4","Cell RNA - MOLT-4 [nTPM]":"25.5","Cell RNA - NB-4 [nTPM]":"107.2","Cell RNA - NTERA-2 [nTPM]":"27.1","Cell RNA - OE19 [nTPM]":"65.1","Cell RNA - PC-3 [nTPM]":"15.7","Cell RNA - REH [nTPM]":"49.6","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"66.8","Cell RNA - RPTEC TERT1 [nTPM]":"25.1","Cell RNA - RT4 [nTPM]":"22.9","Cell RNA - SCLC-21H [nTPM]":"58.8","Cell RNA - SH-SY5Y [nTPM]":"41.8","Cell RNA - SiHa [nTPM]":"35.2","Cell RNA - SK-BR-3 [nTPM]":"46.7","Cell RNA - SK-MEL-30 [nTPM]":"72.7","Cell RNA - SuSa [nTPM]":"29.8","Cell RNA - T-47d [nTPM]":"45.1","Cell RNA - THP-1 [nTPM]":"277.5","Cell RNA - TIME [nTPM]":"36.8","Cell RNA - U-138 MG [nTPM]":"45.5","Cell RNA - U-2 OS [nTPM]":"19.0","Cell RNA - U-2197 [nTPM]":"34.7","Cell RNA - U-251 MG [nTPM]":"41.6","Cell RNA - U-266\/70 [nTPM]":"122.9","Cell RNA - U-266\/84 [nTPM]":"33.8","Cell RNA - U-698 [nTPM]":"9.1","Cell RNA - U-87 MG [nTPM]":"23.1","Cell RNA - U-937 [nTPM]":"89.6","Cell RNA - WM-115 [nTPM]":"63.4","Blood RNA - basophil [nTPM]":"10.1","Blood RNA - classical monocyte [nTPM]":"4.5","Blood RNA - eosinophil [nTPM]":"8.5","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"4.7","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"17.8","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"43.3","Brain RNA - basal ganglia [nTPM]":"50.2","Brain RNA - cerebellum [nTPM]":"48.5","Brain RNA - cerebral cortex [nTPM]":"49.1","Brain RNA - hippocampal formation [nTPM]":"40.5","Brain RNA - hypothalamus [nTPM]":"45.4","Brain RNA - medulla oblongata [nTPM]":"55.2","Brain RNA - midbrain [nTPM]":"49.0","Brain RNA - pons [nTPM]":"51.1","Brain RNA - spinal cord [nTPM]":"48.9","Brain RNA - thalamus [nTPM]":"44.7","Brain RNA - white matter [nTPM]":"61.1","Single Cell Type RNA - Adipocytes [nTPM]":"96.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"134.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"191.3","Single Cell Type RNA - Astrocytes [nTPM]":"28.1","Single Cell Type RNA - B-cells [nTPM]":"75.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"325.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"440.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"142.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"139.5","Single Cell Type RNA - Bipolar cells [nTPM]":"34.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"126.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"109.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"63.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"133.0","Single Cell Type RNA - Club cells [nTPM]":"143.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"44.6","Single Cell Type RNA - dendritic cells [nTPM]":"168.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"84.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"65.8","Single Cell Type RNA - Early spermatids [nTPM]":"24.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"180.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"126.2","Single Cell Type RNA - Endothelial cells [nTPM]":"101.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"145.5","Single Cell Type RNA - Erythroid cells [nTPM]":"76.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"50.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.0","Single Cell Type RNA - Fibroblasts [nTPM]":"97.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"285.2","Single Cell Type RNA - granulocytes [nTPM]":"107.5","Single Cell Type RNA - Granulosa cells [nTPM]":"39.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"117.4","Single Cell Type RNA - Hepatocytes [nTPM]":"185.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.9","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"117.1","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"131.8","Single Cell Type RNA - Langerhans cells [nTPM]":"271.2","Single Cell Type RNA - Late spermatids [nTPM]":"27.1","Single Cell Type RNA - Leydig cells [nTPM]":"69.6","Single Cell Type RNA - Macrophages [nTPM]":"159.7","Single Cell Type RNA - Melanocytes [nTPM]":"110.3","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"83.2","Single Cell Type RNA - Muller glia cells [nTPM]":"87.7","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"68.9","Single Cell Type RNA - Paneth cells [nTPM]":"92.0","Single Cell Type RNA - Peritubular cells [nTPM]":"81.3","Single Cell Type RNA - Plasma cells [nTPM]":"39.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"138.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"81.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"95.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.5","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"117.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"102.9","Single Cell Type RNA - Spermatocytes [nTPM]":"29.5","Single Cell Type RNA - Spermatogonia [nTPM]":"24.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"182.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"396.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"79.4","Single Cell Type RNA - T-cells [nTPM]":"91.3","Single Cell Type RNA - Theca cells [nTPM]":"15.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"162.7","Single Cell Type RNA - Urothelial cells [nTPM]":"370.6"},{"Gene":"IRF8","Gene synonym":["ICSBP","ICSBP1","IRF-8"],"Ensembl":"ENSG00000140968","Gene description":"Interferon regulatory factor 8","Uniprot":["Q02556"],"Chromosome":"16","Position":"85899162-85922606","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Autophagy","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"85.5","lymphoid tissue":"244.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"225.8","dendritic cells":"492.3","Kupffer cells":"105.1","Langerhans cells":"366.0","Macrophages":"122.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"plasmacytoid DC":"2477.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"2477.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Daudi":"240.7","THP-1":"382.3","U-698":"928.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002267","HPA002531","CAB013480"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013480":"AB_2533439","HPA002267":"AB_1079143","HPA002531":"AB_1851904"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"25.9","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"81.4","Tissue RNA - basal ganglia [nTPM]":"5.6","Tissue RNA - bone marrow [nTPM]":"85.5","Tissue RNA - breast [nTPM]":"9.3","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"6.2","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"5.4","Tissue RNA - colon [nTPM]":"27.1","Tissue RNA - duodenum [nTPM]":"47.1","Tissue RNA - endometrium 1 [nTPM]":"8.0","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"36.9","Tissue RNA - lung [nTPM]":"27.4","Tissue RNA - lymph node [nTPM]":"244.1","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"3.4","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"10.0","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"33.5","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"56.2","Tissue RNA - smooth muscle [nTPM]":"13.5","Tissue RNA - spinal cord [nTPM]":"11.3","Tissue RNA - spleen [nTPM]":"137.3","Tissue RNA - stomach 1 [nTPM]":"22.9","Tissue RNA - testis [nTPM]":"4.8","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"61.5","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"224.9","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"14.0","Cell RNA - A-431 [nTPM]":"0.9","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"16.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"26.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"240.7","Cell RNA - EFO-21 [nTPM]":"1.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.7","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"21.3","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"20.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"27.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"382.3","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"928.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"128.4","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"137.1","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"134.3","Blood RNA - MAIT T-cell [nTPM]":"4.5","Blood RNA - memory B-cell [nTPM]":"347.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"291.2","Blood RNA - naive B-cell [nTPM]":"361.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"8.4","Blood RNA - NK-cell [nTPM]":"111.5","Blood RNA - non-classical monocyte [nTPM]":"97.3","Blood RNA - plasmacytoid DC [nTPM]":"2477.4","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"150.1","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"5.6","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"6.2","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"10.0","Brain RNA - spinal cord [nTPM]":"11.3","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"14.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"225.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"492.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.7","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"10.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.5","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"6.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"64.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"105.1","Single Cell Type RNA - Langerhans cells [nTPM]":"366.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"122.2","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"35.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"6.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"23.1","Single Cell Type RNA - Theca cells [nTPM]":"48.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"25.6","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"ISG15","Gene synonym":["G1P2","IFI15","UCRP"],"Ensembl":"ENSG00000187608","Gene description":"ISG15 ubiquitin like modifier","Uniprot":["P05161"],"Chromosome":"1","Position":"1001138-1014540","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Antiviral defense","Host-virus interaction","Immunity","Innate immunity","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"320.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"497.1","Paneth cells":"403.1","Proximal enterocytes":"461.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+":"1460.2","BJ hTERT+ SV40 Large T+ RasG12V":"1466.7","HeLa":"501.4","SK-MEL-30":"487.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004627"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":5000000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004627":"AB_1079152"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.11e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"46.8","Tissue RNA - adrenal gland [nTPM]":"24.3","Tissue RNA - amygdala [nTPM]":"42.9","Tissue RNA - appendix [nTPM]":"36.9","Tissue RNA - basal ganglia [nTPM]":"39.8","Tissue RNA - bone marrow [nTPM]":"136.1","Tissue RNA - breast [nTPM]":"39.0","Tissue RNA - cerebellum [nTPM]":"42.0","Tissue RNA - cerebral cortex [nTPM]":"49.9","Tissue RNA - cervix [nTPM]":"79.0","Tissue RNA - choroid plexus [nTPM]":"32.6","Tissue RNA - colon [nTPM]":"47.0","Tissue RNA - duodenum [nTPM]":"42.5","Tissue RNA - endometrium 1 [nTPM]":"29.6","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"19.9","Tissue RNA - gallbladder [nTPM]":"31.3","Tissue RNA - heart muscle [nTPM]":"55.4","Tissue RNA - hippocampal formation [nTPM]":"38.3","Tissue RNA - hypothalamus [nTPM]":"36.8","Tissue RNA - kidney [nTPM]":"73.2","Tissue RNA - liver [nTPM]":"113.5","Tissue RNA - lung [nTPM]":"59.9","Tissue RNA - lymph node [nTPM]":"29.7","Tissue RNA - medulla oblongata [nTPM]":"63.2","Tissue RNA - midbrain [nTPM]":"42.7","Tissue RNA - ovary [nTPM]":"17.6","Tissue RNA - pancreas [nTPM]":"18.9","Tissue RNA - parathyroid gland [nTPM]":"8.8","Tissue RNA - pituitary gland [nTPM]":"40.3","Tissue RNA - placenta [nTPM]":"44.8","Tissue RNA - pons [nTPM]":"63.8","Tissue RNA - prostate [nTPM]":"28.1","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"320.4","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"15.9","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"34.8","Tissue RNA - smooth muscle [nTPM]":"18.2","Tissue RNA - spinal cord [nTPM]":"134.8","Tissue RNA - spleen [nTPM]":"75.3","Tissue RNA - stomach 1 [nTPM]":"31.3","Tissue RNA - testis [nTPM]":"10.5","Tissue RNA - thalamus [nTPM]":"48.7","Tissue RNA - thymus [nTPM]":"48.5","Tissue RNA - thyroid gland [nTPM]":"34.7","Tissue RNA - tongue [nTPM]":"8.1","Tissue RNA - tonsil [nTPM]":"11.6","Tissue RNA - urinary bladder [nTPM]":"29.2","Tissue RNA - vagina [nTPM]":"25.7","Tissue RNA - white matter [nTPM]":"38.3","Cell RNA - A-431 [nTPM]":"58.1","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"4.4","Cell RNA - AN3-CA [nTPM]":"38.2","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"33.2","Cell RNA - BJ [nTPM]":"39.5","Cell RNA - BJ hTERT+ [nTPM]":"95.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1460.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1466.7","Cell RNA - CACO-2 [nTPM]":"95.6","Cell RNA - CAPAN-2 [nTPM]":"91.7","Cell RNA - Daudi [nTPM]":"51.4","Cell RNA - EFO-21 [nTPM]":"282.0","Cell RNA - fHDF\/TERT166 [nTPM]":"33.4","Cell RNA - GAMG [nTPM]":"248.2","Cell RNA - HaCaT [nTPM]":"36.1","Cell RNA - HAP1 [nTPM]":"4.5","Cell RNA - HBEC3-KT [nTPM]":"17.3","Cell RNA - HBF TERT88 [nTPM]":"22.7","Cell RNA - HDLM-2 [nTPM]":"58.2","Cell RNA - HEK 293 [nTPM]":"23.7","Cell RNA - HEL [nTPM]":"24.3","Cell RNA - HeLa [nTPM]":"501.4","Cell RNA - Hep G2 [nTPM]":"65.2","Cell RNA - HHSteC [nTPM]":"53.8","Cell RNA - HL-60 [nTPM]":"15.4","Cell RNA - HMC-1 [nTPM]":"94.5","Cell RNA - HSkMC [nTPM]":"24.6","Cell RNA - hTCEpi [nTPM]":"5.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"92.7","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"4.8","Cell RNA - HUVEC TERT2 [nTPM]":"46.1","Cell RNA - JURKAT [nTPM]":"67.7","Cell RNA - K-562 [nTPM]":"14.1","Cell RNA - Karpas-707 [nTPM]":"27.4","Cell RNA - LHCN-M2 [nTPM]":"12.0","Cell RNA - MCF7 [nTPM]":"282.3","Cell RNA - MOLT-4 [nTPM]":"50.0","Cell RNA - NB-4 [nTPM]":"253.5","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"36.3","Cell RNA - PC-3 [nTPM]":"315.3","Cell RNA - REH [nTPM]":"85.7","Cell RNA - RH-30 [nTPM]":"11.0","Cell RNA - RPMI-8226 [nTPM]":"26.1","Cell RNA - RPTEC TERT1 [nTPM]":"19.2","Cell RNA - RT4 [nTPM]":"18.0","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"77.1","Cell RNA - SK-BR-3 [nTPM]":"12.6","Cell RNA - SK-MEL-30 [nTPM]":"487.0","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"29.8","Cell RNA - TIME [nTPM]":"25.8","Cell RNA - U-138 MG [nTPM]":"28.5","Cell RNA - U-2 OS [nTPM]":"27.4","Cell RNA - U-2197 [nTPM]":"13.2","Cell RNA - U-251 MG [nTPM]":"8.7","Cell RNA - U-266\/70 [nTPM]":"35.5","Cell RNA - U-266\/84 [nTPM]":"19.6","Cell RNA - U-698 [nTPM]":"39.6","Cell RNA - U-87 MG [nTPM]":"27.9","Cell RNA - U-937 [nTPM]":"60.2","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"508.7","Blood RNA - classical monocyte [nTPM]":"278.6","Blood RNA - eosinophil [nTPM]":"871.3","Blood RNA - gdT-cell [nTPM]":"228.3","Blood RNA - intermediate monocyte [nTPM]":"425.4","Blood RNA - MAIT T-cell [nTPM]":"295.5","Blood RNA - memory B-cell [nTPM]":"259.1","Blood RNA - memory CD4 T-cell [nTPM]":"258.6","Blood RNA - memory CD8 T-cell [nTPM]":"251.7","Blood RNA - myeloid DC [nTPM]":"174.8","Blood RNA - naive B-cell [nTPM]":"215.7","Blood RNA - naive CD4 T-cell [nTPM]":"165.2","Blood RNA - naive CD8 T-cell [nTPM]":"191.1","Blood RNA - neutrophil [nTPM]":"663.3","Blood RNA - NK-cell [nTPM]":"276.7","Blood RNA - non-classical monocyte [nTPM]":"381.1","Blood RNA - plasmacytoid DC [nTPM]":"59.4","Blood RNA - T-reg [nTPM]":"509.7","Blood RNA - total PBMC [nTPM]":"217.6","Brain RNA - amygdala [nTPM]":"42.9","Brain RNA - basal ganglia [nTPM]":"39.8","Brain RNA - cerebellum [nTPM]":"42.0","Brain RNA - cerebral cortex [nTPM]":"49.9","Brain RNA - hippocampal formation [nTPM]":"38.3","Brain RNA - hypothalamus [nTPM]":"36.8","Brain RNA - medulla oblongata [nTPM]":"63.2","Brain RNA - midbrain [nTPM]":"42.7","Brain RNA - pons [nTPM]":"63.8","Brain RNA - spinal cord [nTPM]":"134.8","Brain RNA - thalamus [nTPM]":"48.7","Brain RNA - white matter [nTPM]":"38.3","Single Cell Type RNA - Adipocytes [nTPM]":"240.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"71.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"44.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"83.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"61.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - dendritic cells [nTPM]":"213.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"289.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"134.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"65.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"66.1","Single Cell Type RNA - Endothelial cells [nTPM]":"200.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"280.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"497.1","Single Cell Type RNA - Fibroblasts [nTPM]":"84.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.4","Single Cell Type RNA - granulocytes [nTPM]":"60.9","Single Cell Type RNA - Granulosa cells [nTPM]":"113.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"70.6","Single Cell Type RNA - Hepatocytes [nTPM]":"58.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"273.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"104.9","Single Cell Type RNA - Ionocytes [nTPM]":"63.1","Single Cell Type RNA - Kupffer cells [nTPM]":"62.0","Single Cell Type RNA - Langerhans cells [nTPM]":"273.8","Single Cell Type RNA - Late spermatids [nTPM]":"14.0","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"170.4","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"132.5","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"134.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"192.0","Single Cell Type RNA - Paneth cells [nTPM]":"403.1","Single Cell Type RNA - Peritubular cells [nTPM]":"41.3","Single Cell Type RNA - Plasma cells [nTPM]":"48.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"461.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"32.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.2","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"179.1","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.3","Single Cell Type RNA - T-cells [nTPM]":"169.4","Single Cell Type RNA - Theca cells [nTPM]":"63.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.5","Single Cell Type RNA - Urothelial cells [nTPM]":"55.4"},{"Gene":"ITGB2","Gene synonym":["CD18","LFA-1","MAC-1","MFI7"],"Ensembl":"ENSG00000160255","Gene description":"Integrin subunit beta 2","Uniprot":["P05107"],"Chromosome":"21","Position":"44885953-44931989","Protein class":["CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Phagocytosis"],"Molecular function":["Integrin","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"376.2","lymphoid tissue":"175.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"dendritic cells":"417.6","Hofbauer cells":"652.4","Kupffer cells":"485.9","Langerhans cells":"259.1","Macrophages":"527.4","monocytes":"463.8","NK-cells":"959.9","T-cells":"254.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"THP-1":"812.4","U-937":"615.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008877","HPA016894"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Rods & Rings"],"Antibody RRID":{"HPA008877":"AB_1846256","HPA016894":"AB_1846257"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"54.5","Tissue RNA - adrenal gland [nTPM]":"23.2","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"175.2","Tissue RNA - basal ganglia [nTPM]":"9.5","Tissue RNA - bone marrow [nTPM]":"376.2","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"13.1","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"25.2","Tissue RNA - duodenum [nTPM]":"23.8","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"16.2","Tissue RNA - fallopian tube [nTPM]":"17.0","Tissue RNA - gallbladder [nTPM]":"36.4","Tissue RNA - heart muscle [nTPM]":"11.8","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"8.4","Tissue RNA - liver [nTPM]":"23.4","Tissue RNA - lung [nTPM]":"78.0","Tissue RNA - lymph node [nTPM]":"169.1","Tissue RNA - medulla oblongata [nTPM]":"29.5","Tissue RNA - midbrain [nTPM]":"19.9","Tissue RNA - ovary [nTPM]":"7.2","Tissue RNA - pancreas [nTPM]":"11.3","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"44.4","Tissue RNA - pons [nTPM]":"28.1","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"13.9","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"19.5","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"6.8","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"32.8","Tissue RNA - smooth muscle [nTPM]":"46.4","Tissue RNA - spinal cord [nTPM]":"23.9","Tissue RNA - spleen [nTPM]":"137.2","Tissue RNA - stomach 1 [nTPM]":"29.1","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"26.2","Tissue RNA - thymus [nTPM]":"87.2","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"68.4","Tissue RNA - urinary bladder [nTPM]":"46.3","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"50.4","Cell RNA - A-431 [nTPM]":"1.9","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"17.9","Cell RNA - EFO-21 [nTPM]":"128.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.5","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"18.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"106.6","Cell RNA - HMC-1 [nTPM]":"27.5","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"58.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"7.0","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"117.8","Cell RNA - NB-4 [nTPM]":"126.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"1.5","Cell RNA - RH-30 [nTPM]":"23.2","Cell RNA - RPMI-8226 [nTPM]":"64.6","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"1.3","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"812.4","Cell RNA - TIME [nTPM]":"2.5","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"3.7","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"5.9","Cell RNA - U-698 [nTPM]":"2.9","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"615.0","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"186.6","Blood RNA - classical monocyte [nTPM]":"1848.8","Blood RNA - eosinophil [nTPM]":"1224.1","Blood RNA - gdT-cell [nTPM]":"726.7","Blood RNA - intermediate monocyte [nTPM]":"1144.9","Blood RNA - MAIT T-cell [nTPM]":"326.6","Blood RNA - memory B-cell [nTPM]":"86.1","Blood RNA - memory CD4 T-cell [nTPM]":"349.7","Blood RNA - memory CD8 T-cell [nTPM]":"506.5","Blood RNA - myeloid DC [nTPM]":"1031.4","Blood RNA - naive B-cell [nTPM]":"115.2","Blood RNA - naive CD4 T-cell [nTPM]":"233.1","Blood RNA - naive CD8 T-cell [nTPM]":"396.5","Blood RNA - neutrophil [nTPM]":"1386.1","Blood RNA - NK-cell [nTPM]":"585.5","Blood RNA - non-classical monocyte [nTPM]":"1183.5","Blood RNA - plasmacytoid DC [nTPM]":"165.5","Blood RNA - T-reg [nTPM]":"288.0","Blood RNA - total PBMC [nTPM]":"3034.2","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"9.5","Brain RNA - cerebellum [nTPM]":"13.1","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"29.5","Brain RNA - midbrain [nTPM]":"19.9","Brain RNA - pons [nTPM]":"28.1","Brain RNA - spinal cord [nTPM]":"23.9","Brain RNA - thalamus [nTPM]":"26.2","Brain RNA - white matter [nTPM]":"50.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"81.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"18.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - dendritic cells [nTPM]":"417.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"16.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"652.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"485.9","Single Cell Type RNA - Langerhans cells [nTPM]":"259.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"527.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"463.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"959.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"50.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"254.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"ITK","Gene synonym":["EMT","LYK","PSCTK2"],"Ensembl":"ENSG00000113263","Gene description":"IL2 inducible T cell kinase","Uniprot":["Q08881"],"Chromosome":"5","Position":"157142933-157255185","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"14","RNA tissue specific nTPM":{"lymphoid tissue":"57.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"dendritic cells":"51.7","granulocytes":"31.8","NK-cells":"42.2","Plasma cells":"34.0","T-cells":"115.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"23","RNA blood cell specific nTPM":{"gdT-cell":"39.6","MAIT T-cell":"26.4","memory CD4 T-cell":"55.6","memory CD8 T-cell":"54.9","naive CD4 T-cell":"78.2","naive CD8 T-cell":"65.0","NK-cell":"29.3","T-reg":"73.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"23","RNA blood lineage specific nTPM":{"NK-cells":"29.3","T-cells":"78.2"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"JURKAT":"62.2","MOLT-4":"23.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043670"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA043670":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.57e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"15.9","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"3.7","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"3.1","Tissue RNA - lymph node [nTPM]":"29.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"4.0","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"10.5","Tissue RNA - stomach 1 [nTPM]":"3.1","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"57.9","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"24.6","Tissue RNA - urinary bladder [nTPM]":"3.9","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"3.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"62.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"23.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"39.6","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"26.4","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"55.6","Blood RNA - memory CD8 T-cell [nTPM]":"54.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"78.2","Blood RNA - naive CD8 T-cell [nTPM]":"65.0","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"29.3","Blood RNA - non-classical monocyte [nTPM]":"2.3","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"73.2","Blood RNA - total PBMC [nTPM]":"44.3","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"51.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"8.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"31.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"34.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"115.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"JAK3","Gene synonym":["JAK-3","JAK3_HUMAN","JAKL","L-JAK","LJAK"],"Ensembl":"ENSG00000105639","Gene description":"Janus kinase 3","Uniprot":["P52333"],"Chromosome":"19","Position":"17824780-17848071","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"55.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"27.8","dendritic cells":"20.1","Macrophages":"17.9","NK-cells":"18.6","Plasma cells":"18.4","T-cells":"37.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"35.7","HEL":"15.9","HMC-1":"15.5","Karpas-707":"40.2","U-266\/70":"15.4","U-266\/84":"24.7","U-937":"24.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070314"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 58: T-cells - T-cell receptor","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA070314":"AB_2686251"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.42e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.89e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"36.3","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"18.6","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"5.3","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"3.2","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"13.1","Tissue RNA - lymph node [nTPM]":"40.5","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"15.5","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"1.9","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"3.1","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"15.4","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"5.5","Tissue RNA - spleen [nTPM]":"55.1","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"7.4","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"1.8","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"2.4","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"35.7","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"15.9","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"15.5","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"3.6","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"40.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"6.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.9","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"8.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"15.4","Cell RNA - U-266\/84 [nTPM]":"24.7","Cell RNA - U-698 [nTPM]":"4.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"24.2","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"7.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"17.8","Blood RNA - intermediate monocyte [nTPM]":"14.6","Blood RNA - MAIT T-cell [nTPM]":"20.2","Blood RNA - memory B-cell [nTPM]":"9.4","Blood RNA - memory CD4 T-cell [nTPM]":"21.1","Blood RNA - memory CD8 T-cell [nTPM]":"18.6","Blood RNA - myeloid DC [nTPM]":"6.8","Blood RNA - naive B-cell [nTPM]":"10.3","Blood RNA - naive CD4 T-cell [nTPM]":"20.2","Blood RNA - naive CD8 T-cell [nTPM]":"18.5","Blood RNA - neutrophil [nTPM]":"25.1","Blood RNA - NK-cell [nTPM]":"13.4","Blood RNA - non-classical monocyte [nTPM]":"14.2","Blood RNA - plasmacytoid DC [nTPM]":"5.5","Blood RNA - T-reg [nTPM]":"18.0","Blood RNA - total PBMC [nTPM]":"12.4","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"5.5","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"27.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"20.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"4.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"17.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"16.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"18.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"37.7","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"LAMTOR2","Gene synonym":["ENDAP","MAPBPIP","MAPKSP1AP","p14","Ragulator2","ROBLD3"],"Ensembl":"ENSG00000116586","Gene description":"Late endosomal\/lysosomal adaptor, MAPK and MTOR activator 2","Uniprot":["Q9Y2Q5"],"Chromosome":"1","Position":"156054782-156058506","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal tubular cells":"627.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004126"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA004126":"AB_1849916"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.10e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"64.3","Tissue RNA - adrenal gland [nTPM]":"84.4","Tissue RNA - amygdala [nTPM]":"81.9","Tissue RNA - appendix [nTPM]":"41.6","Tissue RNA - basal ganglia [nTPM]":"81.4","Tissue RNA - bone marrow [nTPM]":"57.1","Tissue RNA - breast [nTPM]":"57.7","Tissue RNA - cerebellum [nTPM]":"83.9","Tissue RNA - cerebral cortex [nTPM]":"98.9","Tissue RNA - cervix [nTPM]":"44.8","Tissue RNA - choroid plexus [nTPM]":"83.0","Tissue RNA - colon [nTPM]":"62.0","Tissue RNA - duodenum [nTPM]":"51.5","Tissue RNA - endometrium 1 [nTPM]":"42.3","Tissue RNA - epididymis [nTPM]":"76.7","Tissue RNA - esophagus [nTPM]":"75.2","Tissue RNA - fallopian tube [nTPM]":"52.1","Tissue RNA - gallbladder [nTPM]":"43.8","Tissue RNA - heart muscle [nTPM]":"96.1","Tissue RNA - hippocampal formation [nTPM]":"81.6","Tissue RNA - hypothalamus [nTPM]":"84.7","Tissue RNA - kidney [nTPM]":"91.0","Tissue RNA - liver [nTPM]":"164.3","Tissue RNA - lung [nTPM]":"53.8","Tissue RNA - lymph node [nTPM]":"56.3","Tissue RNA - medulla oblongata [nTPM]":"81.6","Tissue RNA - midbrain [nTPM]":"82.5","Tissue RNA - ovary [nTPM]":"26.7","Tissue RNA - pancreas [nTPM]":"87.8","Tissue RNA - parathyroid gland [nTPM]":"74.4","Tissue RNA - pituitary gland [nTPM]":"44.6","Tissue RNA - placenta [nTPM]":"37.5","Tissue RNA - pons [nTPM]":"82.0","Tissue RNA - prostate [nTPM]":"50.9","Tissue RNA - rectum [nTPM]":"56.5","Tissue RNA - retina [nTPM]":"18.0","Tissue RNA - salivary gland [nTPM]":"59.3","Tissue RNA - seminal vesicle [nTPM]":"44.0","Tissue RNA - skeletal muscle [nTPM]":"88.6","Tissue RNA - skin 1 [nTPM]":"57.8","Tissue RNA - small intestine [nTPM]":"53.7","Tissue RNA - smooth muscle [nTPM]":"48.9","Tissue RNA - spinal cord [nTPM]":"82.2","Tissue RNA - spleen [nTPM]":"65.7","Tissue RNA - stomach 1 [nTPM]":"78.1","Tissue RNA - testis [nTPM]":"26.6","Tissue RNA - thalamus [nTPM]":"85.8","Tissue RNA - thymus [nTPM]":"56.1","Tissue RNA - thyroid gland [nTPM]":"44.7","Tissue RNA - tongue [nTPM]":"70.2","Tissue RNA - tonsil [nTPM]":"52.0","Tissue RNA - urinary bladder [nTPM]":"53.6","Tissue RNA - vagina [nTPM]":"46.7","Tissue RNA - white matter [nTPM]":"85.8","Cell RNA - A-431 [nTPM]":"63.9","Cell RNA - A549 [nTPM]":"142.3","Cell RNA - AF22 [nTPM]":"65.4","Cell RNA - AN3-CA [nTPM]":"90.9","Cell RNA - ASC diff [nTPM]":"131.9","Cell RNA - ASC TERT1 [nTPM]":"106.7","Cell RNA - BEWO [nTPM]":"72.3","Cell RNA - BJ [nTPM]":"55.7","Cell RNA - BJ hTERT+ [nTPM]":"94.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"78.1","Cell RNA - CACO-2 [nTPM]":"65.9","Cell RNA - CAPAN-2 [nTPM]":"106.1","Cell RNA - Daudi [nTPM]":"94.0","Cell RNA - EFO-21 [nTPM]":"94.4","Cell RNA - fHDF\/TERT166 [nTPM]":"108.7","Cell RNA - GAMG [nTPM]":"60.0","Cell RNA - HaCaT [nTPM]":"91.5","Cell RNA - HAP1 [nTPM]":"67.7","Cell RNA - HBEC3-KT [nTPM]":"151.1","Cell RNA - HBF TERT88 [nTPM]":"38.7","Cell RNA - HDLM-2 [nTPM]":"78.4","Cell RNA - HEK 293 [nTPM]":"103.0","Cell RNA - HEL [nTPM]":"54.9","Cell RNA - HeLa [nTPM]":"96.2","Cell RNA - Hep G2 [nTPM]":"88.6","Cell RNA - HHSteC [nTPM]":"104.4","Cell RNA - HL-60 [nTPM]":"78.0","Cell RNA - HMC-1 [nTPM]":"86.5","Cell RNA - HSkMC [nTPM]":"126.1","Cell RNA - hTCEpi [nTPM]":"93.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"73.1","Cell RNA - hTERT-HME1 [nTPM]":"93.3","Cell RNA - hTERT-RPE1 [nTPM]":"94.4","Cell RNA - HUVEC TERT2 [nTPM]":"142.6","Cell RNA - JURKAT [nTPM]":"137.3","Cell RNA - K-562 [nTPM]":"50.8","Cell RNA - Karpas-707 [nTPM]":"68.1","Cell RNA - LHCN-M2 [nTPM]":"100.9","Cell RNA - MCF7 [nTPM]":"128.7","Cell RNA - MOLT-4 [nTPM]":"80.6","Cell RNA - NB-4 [nTPM]":"111.4","Cell RNA - NTERA-2 [nTPM]":"69.4","Cell RNA - OE19 [nTPM]":"250.9","Cell RNA - PC-3 [nTPM]":"212.1","Cell RNA - REH [nTPM]":"67.5","Cell RNA - RH-30 [nTPM]":"48.7","Cell RNA - RPMI-8226 [nTPM]":"138.7","Cell RNA - RPTEC TERT1 [nTPM]":"152.5","Cell RNA - RT4 [nTPM]":"93.2","Cell RNA - SCLC-21H [nTPM]":"25.3","Cell RNA - SH-SY5Y [nTPM]":"145.3","Cell RNA - SiHa [nTPM]":"70.4","Cell RNA - SK-BR-3 [nTPM]":"195.1","Cell RNA - SK-MEL-30 [nTPM]":"116.3","Cell RNA - SuSa [nTPM]":"104.1","Cell RNA - T-47d [nTPM]":"136.5","Cell RNA - THP-1 [nTPM]":"227.9","Cell RNA - TIME [nTPM]":"96.6","Cell RNA - U-138 MG [nTPM]":"57.5","Cell RNA - U-2 OS [nTPM]":"52.4","Cell RNA - U-2197 [nTPM]":"83.4","Cell RNA - U-251 MG [nTPM]":"53.0","Cell RNA - U-266\/70 [nTPM]":"101.6","Cell RNA - U-266\/84 [nTPM]":"166.5","Cell RNA - U-698 [nTPM]":"56.2","Cell RNA - U-87 MG [nTPM]":"102.2","Cell RNA - U-937 [nTPM]":"87.3","Cell RNA - WM-115 [nTPM]":"62.9","Blood RNA - basophil [nTPM]":"281.8","Blood RNA - classical monocyte [nTPM]":"465.8","Blood RNA - eosinophil [nTPM]":"376.2","Blood RNA - gdT-cell [nTPM]":"172.2","Blood RNA - intermediate monocyte [nTPM]":"446.9","Blood RNA - MAIT T-cell [nTPM]":"169.8","Blood RNA - memory B-cell [nTPM]":"290.6","Blood RNA - memory CD4 T-cell [nTPM]":"188.2","Blood RNA - memory CD8 T-cell [nTPM]":"188.7","Blood RNA - myeloid DC [nTPM]":"537.2","Blood RNA - naive B-cell [nTPM]":"249.4","Blood RNA - naive CD4 T-cell [nTPM]":"142.6","Blood RNA - naive CD8 T-cell [nTPM]":"152.8","Blood RNA - neutrophil [nTPM]":"231.8","Blood RNA - NK-cell [nTPM]":"207.0","Blood RNA - non-classical monocyte [nTPM]":"363.2","Blood RNA - plasmacytoid DC [nTPM]":"284.1","Blood RNA - T-reg [nTPM]":"298.3","Blood RNA - total PBMC [nTPM]":"389.7","Brain RNA - amygdala [nTPM]":"81.9","Brain RNA - basal ganglia [nTPM]":"81.4","Brain RNA - cerebellum [nTPM]":"83.9","Brain RNA - cerebral cortex [nTPM]":"98.9","Brain RNA - hippocampal formation [nTPM]":"81.6","Brain RNA - hypothalamus [nTPM]":"84.7","Brain RNA - medulla oblongata [nTPM]":"81.6","Brain RNA - midbrain [nTPM]":"82.5","Brain RNA - pons [nTPM]":"82.0","Brain RNA - spinal cord [nTPM]":"82.2","Brain RNA - thalamus [nTPM]":"85.8","Brain RNA - white matter [nTPM]":"85.8","Single Cell Type RNA - Adipocytes [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.5","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"64.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"48.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"190.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"129.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"123.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"113.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"114.4","Single Cell Type RNA - Club cells [nTPM]":"120.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"108.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"146.3","Single Cell Type RNA - dendritic cells [nTPM]":"73.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"247.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"387.4","Single Cell Type RNA - Ductal cells [nTPM]":"193.0","Single Cell Type RNA - Early spermatids [nTPM]":"44.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"113.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"78.7","Single Cell Type RNA - Endothelial cells [nTPM]":"92.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"126.1","Single Cell Type RNA - Erythroid cells [nTPM]":"48.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"179.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"203.1","Single Cell Type RNA - Fibroblasts [nTPM]":"67.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"68.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"105.0","Single Cell Type RNA - granulocytes [nTPM]":"107.3","Single Cell Type RNA - Granulosa cells [nTPM]":"56.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"86.7","Single Cell Type RNA - Hepatocytes [nTPM]":"322.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"416.1","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"164.7","Single Cell Type RNA - Ionocytes [nTPM]":"197.4","Single Cell Type RNA - Kupffer cells [nTPM]":"188.9","Single Cell Type RNA - Langerhans cells [nTPM]":"150.1","Single Cell Type RNA - Late spermatids [nTPM]":"89.0","Single Cell Type RNA - Leydig cells [nTPM]":"47.2","Single Cell Type RNA - Macrophages [nTPM]":"165.0","Single Cell Type RNA - Melanocytes [nTPM]":"158.3","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"297.4","Single Cell Type RNA - Muller glia cells [nTPM]":"92.8","Single Cell Type RNA - NK-cells [nTPM]":"94.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"183.2","Single Cell Type RNA - Paneth cells [nTPM]":"267.4","Single Cell Type RNA - Peritubular cells [nTPM]":"50.8","Single Cell Type RNA - Plasma cells [nTPM]":"76.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"80.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"317.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"627.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"144.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"124.6","Single Cell Type RNA - Spermatocytes [nTPM]":"25.5","Single Cell Type RNA - Spermatogonia [nTPM]":"33.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"99.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.2","Single Cell Type RNA - T-cells [nTPM]":"64.2","Single Cell Type RNA - Theca cells [nTPM]":"83.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"166.9","Single Cell Type RNA - Urothelial cells [nTPM]":"97.7"},{"Gene":"LCK","Gene synonym":[],"Ensembl":"ENSG00000182866","Gene description":"LCK proto-oncogene, Src family tyrosine kinase","Uniprot":["P06239"],"Chromosome":"1","Position":"32251239-32286165","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"lymphoid tissue":"343.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"dendritic cells":"143.9","NK-cells":"272.9","T-cells":"255.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"12","RNA blood cell specific nTPM":{"gdT-cell":"1109.8","MAIT T-cell":"1034.8","memory CD4 T-cell":"1123.8","memory CD8 T-cell":"1201.7","naive CD4 T-cell":"1260.7","naive CD8 T-cell":"1168.7","NK-cell":"641.5","T-reg":"1682.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"NK-cells":"641.5","T-cells":"1682.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"JURKAT":"365.7","MOLT-4":"536.9","U-698":"302.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003494","CAB003816"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB003816":"AB_562158","HPA003494":"AB_1852751"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.96e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.78e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.65e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"50.6","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"13.7","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"13.0","Tissue RNA - esophagus [nTPM]":"3.9","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"111.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"2.8","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"23.1","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"39.9","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"343.0","Tissue RNA - thyroid gland [nTPM]":"3.7","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"79.6","Tissue RNA - urinary bladder [nTPM]":"13.2","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.7","Cell RNA - Daudi [nTPM]":"64.1","Cell RNA - EFO-21 [nTPM]":"3.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"365.7","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"536.9","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"4.6","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"20.6","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"302.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"12.8","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"6.0","Blood RNA - gdT-cell [nTPM]":"1109.8","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"1034.8","Blood RNA - memory B-cell [nTPM]":"62.0","Blood RNA - memory CD4 T-cell [nTPM]":"1123.8","Blood RNA - memory CD8 T-cell [nTPM]":"1201.7","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"98.9","Blood RNA - naive CD4 T-cell [nTPM]":"1260.7","Blood RNA - naive CD8 T-cell [nTPM]":"1168.7","Blood RNA - neutrophil [nTPM]":"33.6","Blood RNA - NK-cell [nTPM]":"641.5","Blood RNA - non-classical monocyte [nTPM]":"6.0","Blood RNA - plasmacytoid DC [nTPM]":"7.7","Blood RNA - T-reg [nTPM]":"1682.7","Blood RNA - total PBMC [nTPM]":"1836.9","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"23.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"143.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"10.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"8.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"8.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"272.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"15.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"255.5","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"LIG1","Gene synonym":[],"Ensembl":"ENSG00000105486","Gene description":"DNA ligase 1","Uniprot":["P18858"],"Chromosome":"19","Position":"48115445-48170603","Protein class":["Enzymes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA recombination","DNA repair","DNA replication"],"Molecular function":["Ligase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"34.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037015","HPA041431","HPA048071"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"CAB037015":null,"HPA041431":"AB_2677476","HPA048071":"AB_2680248"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.8","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"3.3","Tissue RNA - appendix [nTPM]":"9.0","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"34.5","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"3.5","Tissue RNA - cervix [nTPM]":"5.5","Tissue RNA - choroid plexus [nTPM]":"2.3","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"8.6","Tissue RNA - endometrium 1 [nTPM]":"4.0","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"4.0","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"15.6","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"7.0","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"3.0","Tissue RNA - skeletal muscle [nTPM]":"3.8","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"20.7","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"43.4","Cell RNA - A549 [nTPM]":"64.1","Cell RNA - AF22 [nTPM]":"57.1","Cell RNA - AN3-CA [nTPM]":"37.6","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"4.2","Cell RNA - BEWO [nTPM]":"41.7","Cell RNA - BJ [nTPM]":"27.0","Cell RNA - BJ hTERT+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.2","Cell RNA - CACO-2 [nTPM]":"35.0","Cell RNA - CAPAN-2 [nTPM]":"42.9","Cell RNA - Daudi [nTPM]":"83.7","Cell RNA - EFO-21 [nTPM]":"15.3","Cell RNA - fHDF\/TERT166 [nTPM]":"11.2","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"30.1","Cell RNA - HAP1 [nTPM]":"24.7","Cell RNA - HBEC3-KT [nTPM]":"26.7","Cell RNA - HBF TERT88 [nTPM]":"16.9","Cell RNA - HDLM-2 [nTPM]":"45.2","Cell RNA - HEK 293 [nTPM]":"48.8","Cell RNA - HEL [nTPM]":"56.4","Cell RNA - HeLa [nTPM]":"38.7","Cell RNA - Hep G2 [nTPM]":"47.5","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"63.0","Cell RNA - HMC-1 [nTPM]":"43.7","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.0","Cell RNA - hTERT-HME1 [nTPM]":"3.4","Cell RNA - hTERT-RPE1 [nTPM]":"5.0","Cell RNA - HUVEC TERT2 [nTPM]":"24.0","Cell RNA - JURKAT [nTPM]":"51.0","Cell RNA - K-562 [nTPM]":"46.3","Cell RNA - Karpas-707 [nTPM]":"29.8","Cell RNA - LHCN-M2 [nTPM]":"23.3","Cell RNA - MCF7 [nTPM]":"44.0","Cell RNA - MOLT-4 [nTPM]":"107.3","Cell RNA - NB-4 [nTPM]":"123.7","Cell RNA - NTERA-2 [nTPM]":"33.6","Cell RNA - OE19 [nTPM]":"46.7","Cell RNA - PC-3 [nTPM]":"15.9","Cell RNA - REH [nTPM]":"84.1","Cell RNA - RH-30 [nTPM]":"48.4","Cell RNA - RPMI-8226 [nTPM]":"43.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.3","Cell RNA - RT4 [nTPM]":"64.8","Cell RNA - SCLC-21H [nTPM]":"36.3","Cell RNA - SH-SY5Y [nTPM]":"36.5","Cell RNA - SiHa [nTPM]":"32.3","Cell RNA - SK-BR-3 [nTPM]":"33.6","Cell RNA - SK-MEL-30 [nTPM]":"10.1","Cell RNA - SuSa [nTPM]":"12.5","Cell RNA - T-47d [nTPM]":"22.7","Cell RNA - THP-1 [nTPM]":"44.5","Cell RNA - TIME [nTPM]":"22.6","Cell RNA - U-138 MG [nTPM]":"31.7","Cell RNA - U-2 OS [nTPM]":"54.3","Cell RNA - U-2197 [nTPM]":"23.9","Cell RNA - U-251 MG [nTPM]":"40.3","Cell RNA - U-266\/70 [nTPM]":"29.3","Cell RNA - U-266\/84 [nTPM]":"49.0","Cell RNA - U-698 [nTPM]":"83.1","Cell RNA - U-87 MG [nTPM]":"12.7","Cell RNA - U-937 [nTPM]":"38.0","Cell RNA - WM-115 [nTPM]":"33.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"7.8","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"7.7","Blood RNA - memory B-cell [nTPM]":"10.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.8","Blood RNA - memory CD8 T-cell [nTPM]":"8.3","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"10.0","Blood RNA - naive CD4 T-cell [nTPM]":"11.5","Blood RNA - naive CD8 T-cell [nTPM]":"8.2","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"12.1","Blood RNA - non-classical monocyte [nTPM]":"3.3","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"10.9","Blood RNA - total PBMC [nTPM]":"5.7","Brain RNA - amygdala [nTPM]":"3.3","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"3.5","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"16.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"21.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.8","Single Cell Type RNA - Early spermatids [nTPM]":"19.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"8.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"36.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.8","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.3","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"23.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"5.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"6.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"6.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"7.2","Single Cell Type RNA - Muller glia cells [nTPM]":"10.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"23.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.5","Single Cell Type RNA - Spermatocytes [nTPM]":"13.5","Single Cell Type RNA - Spermatogonia [nTPM]":"26.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.0","Single Cell Type RNA - T-cells [nTPM]":"13.9","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.3","Single Cell Type RNA - Urothelial cells [nTPM]":"8.7"},{"Gene":"LIG4","Gene synonym":[],"Ensembl":"ENSG00000174405","Gene description":"DNA ligase 4","Uniprot":["P49917"],"Chromosome":"13","Position":"108207439-108218368","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA recombination","DNA repair","DNA replication"],"Molecular function":["Ligase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001334","HPA057325"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"HPA001334":"AB_1078689","HPA057325":"AB_2732608"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-3"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"8.6","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"3.9","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"9.0","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"8.7","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"7.2","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"10.2","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"12.0","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"23.1","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"6.1","Tissue RNA - spleen [nTPM]":"8.3","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"21.8","Tissue RNA - thyroid gland [nTPM]":"7.7","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"6.9","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"15.5","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"15.3","Cell RNA - AN3-CA [nTPM]":"10.2","Cell RNA - ASC diff [nTPM]":"12.4","Cell RNA - ASC TERT1 [nTPM]":"13.3","Cell RNA - BEWO [nTPM]":"5.4","Cell RNA - BJ [nTPM]":"14.9","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.3","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"26.0","Cell RNA - EFO-21 [nTPM]":"11.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"13.7","Cell RNA - HaCaT [nTPM]":"6.3","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"9.9","Cell RNA - HBF TERT88 [nTPM]":"19.2","Cell RNA - HDLM-2 [nTPM]":"15.4","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"12.3","Cell RNA - HeLa [nTPM]":"13.8","Cell RNA - Hep G2 [nTPM]":"3.6","Cell RNA - HHSteC [nTPM]":"14.8","Cell RNA - HL-60 [nTPM]":"16.6","Cell RNA - HMC-1 [nTPM]":"12.5","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"16.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.8","Cell RNA - hTERT-HME1 [nTPM]":"9.6","Cell RNA - hTERT-RPE1 [nTPM]":"10.7","Cell RNA - HUVEC TERT2 [nTPM]":"13.5","Cell RNA - JURKAT [nTPM]":"47.0","Cell RNA - K-562 [nTPM]":"4.4","Cell RNA - Karpas-707 [nTPM]":"4.7","Cell RNA - LHCN-M2 [nTPM]":"17.4","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"27.7","Cell RNA - NB-4 [nTPM]":"12.1","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"12.6","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"25.1","Cell RNA - RH-30 [nTPM]":"6.0","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"14.6","Cell RNA - RT4 [nTPM]":"9.7","Cell RNA - SCLC-21H [nTPM]":"9.6","Cell RNA - SH-SY5Y [nTPM]":"9.9","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"9.0","Cell RNA - SK-MEL-30 [nTPM]":"11.7","Cell RNA - SuSa [nTPM]":"11.7","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"25.4","Cell RNA - TIME [nTPM]":"20.1","Cell RNA - U-138 MG [nTPM]":"6.6","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"13.5","Cell RNA - U-266\/70 [nTPM]":"12.4","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"41.7","Cell RNA - U-87 MG [nTPM]":"25.4","Cell RNA - U-937 [nTPM]":"9.4","Cell RNA - WM-115 [nTPM]":"15.2","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"4.8","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"8.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"9.0","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"10.2","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"6.1","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.5","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.7","Single Cell Type RNA - Endothelial cells [nTPM]":"4.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"9.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.8","Single Cell Type RNA - Spermatocytes [nTPM]":"19.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"4.1","Single Cell Type RNA - Theca cells [nTPM]":"8.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.7"},{"Gene":"LRBA","Gene synonym":["BGL","CDC4L","LAB300","LBA"],"Ensembl":"ENSG00000198589","Gene description":"LPS responsive beige-like anchor protein","Uniprot":["P50851"],"Chromosome":"4","Position":"150264435-151015727","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"213.7","Inhibitory neurons":"192.6","Microglial cells":"161.1","Oligodendrocyte precursor cells":"239.8","Oligodendrocytes":"217.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019366","HPA023597"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"340000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019366":"AB_2138441","HPA023597":"AB_1853256"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.49e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.22e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"10.7","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"11.1","Tissue RNA - breast [nTPM]":"22.7","Tissue RNA - cerebellum [nTPM]":"11.1","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"18.6","Tissue RNA - colon [nTPM]":"16.7","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"14.2","Tissue RNA - esophagus [nTPM]":"13.9","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"9.9","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"23.5","Tissue RNA - liver [nTPM]":"13.4","Tissue RNA - lung [nTPM]":"11.0","Tissue RNA - lymph node [nTPM]":"15.8","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"6.1","Tissue RNA - prostate [nTPM]":"20.0","Tissue RNA - rectum [nTPM]":"17.4","Tissue RNA - retina [nTPM]":"14.9","Tissue RNA - salivary gland [nTPM]":"13.8","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"19.3","Tissue RNA - small intestine [nTPM]":"11.5","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"17.0","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"18.7","Tissue RNA - thyroid gland [nTPM]":"19.1","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"17.7","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"27.6","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"11.9","Cell RNA - AN3-CA [nTPM]":"11.1","Cell RNA - ASC diff [nTPM]":"12.2","Cell RNA - ASC TERT1 [nTPM]":"18.5","Cell RNA - BEWO [nTPM]":"17.0","Cell RNA - BJ [nTPM]":"6.0","Cell RNA - BJ hTERT+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"30.9","Cell RNA - CAPAN-2 [nTPM]":"35.6","Cell RNA - Daudi [nTPM]":"33.7","Cell RNA - EFO-21 [nTPM]":"7.2","Cell RNA - fHDF\/TERT166 [nTPM]":"8.6","Cell RNA - GAMG [nTPM]":"7.5","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"22.1","Cell RNA - HBEC3-KT [nTPM]":"36.6","Cell RNA - HBF TERT88 [nTPM]":"15.3","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"15.8","Cell RNA - HEL [nTPM]":"20.8","Cell RNA - HeLa [nTPM]":"19.8","Cell RNA - Hep G2 [nTPM]":"19.0","Cell RNA - HHSteC [nTPM]":"7.5","Cell RNA - HL-60 [nTPM]":"29.0","Cell RNA - HMC-1 [nTPM]":"16.2","Cell RNA - HSkMC [nTPM]":"14.6","Cell RNA - hTCEpi [nTPM]":"21.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.0","Cell RNA - hTERT-HME1 [nTPM]":"24.6","Cell RNA - hTERT-RPE1 [nTPM]":"23.9","Cell RNA - HUVEC TERT2 [nTPM]":"32.9","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"22.4","Cell RNA - Karpas-707 [nTPM]":"24.3","Cell RNA - LHCN-M2 [nTPM]":"12.9","Cell RNA - MCF7 [nTPM]":"21.9","Cell RNA - MOLT-4 [nTPM]":"21.9","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"10.7","Cell RNA - OE19 [nTPM]":"23.7","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"18.4","Cell RNA - RH-30 [nTPM]":"12.0","Cell RNA - RPMI-8226 [nTPM]":"12.6","Cell RNA - RPTEC TERT1 [nTPM]":"42.0","Cell RNA - RT4 [nTPM]":"33.7","Cell RNA - SCLC-21H [nTPM]":"39.3","Cell RNA - SH-SY5Y [nTPM]":"13.0","Cell RNA - SiHa [nTPM]":"15.1","Cell RNA - SK-BR-3 [nTPM]":"32.1","Cell RNA - SK-MEL-30 [nTPM]":"7.4","Cell RNA - SuSa [nTPM]":"18.1","Cell RNA - T-47d [nTPM]":"32.4","Cell RNA - THP-1 [nTPM]":"6.1","Cell RNA - TIME [nTPM]":"17.2","Cell RNA - U-138 MG [nTPM]":"16.8","Cell RNA - U-2 OS [nTPM]":"12.2","Cell RNA - U-2197 [nTPM]":"8.7","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"20.9","Cell RNA - U-266\/84 [nTPM]":"20.5","Cell RNA - U-698 [nTPM]":"20.5","Cell RNA - U-87 MG [nTPM]":"26.2","Cell RNA - U-937 [nTPM]":"16.0","Cell RNA - WM-115 [nTPM]":"6.6","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"5.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"11.1","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"6.1","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.9","Single Cell Type RNA - Astrocytes [nTPM]":"148.5","Single Cell Type RNA - B-cells [nTPM]":"42.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"33.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"55.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"21.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"148.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.7","Single Cell Type RNA - dendritic cells [nTPM]":"37.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"15.2","Single Cell Type RNA - Early spermatids [nTPM]":"25.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"13.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.0","Single Cell Type RNA - Erythroid cells [nTPM]":"40.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"213.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.8","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"22.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"192.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.8","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"11.1","Single Cell Type RNA - Langerhans cells [nTPM]":"12.8","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"17.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"161.1","Single Cell Type RNA - monocytes [nTPM]":"8.2","Single Cell Type RNA - Muller glia cells [nTPM]":"17.7","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"239.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.2","Single Cell Type RNA - Paneth cells [nTPM]":"20.2","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"38.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"72.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"16.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - T-cells [nTPM]":"45.6","Single Cell Type RNA - Theca cells [nTPM]":"25.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.2","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"LRRC8A","Gene synonym":["FLJ10337","KIAA1437","LRRC8","SWELL1"],"Ensembl":"ENSG00000136802","Gene description":"Leucine rich repeat containing 8 VRAC subunit A","Uniprot":["Q8IWT6"],"Chromosome":"9","Position":"128882133-128918039","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Differentiation","Ion transport","Spermatogenesis","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"192.0","Prostatic glandular cells":"207.0","Urothelial cells":"328.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"163.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.83e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.27e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.4","Tissue RNA - adrenal gland [nTPM]":"17.4","Tissue RNA - amygdala [nTPM]":"68.2","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"69.4","Tissue RNA - bone marrow [nTPM]":"17.3","Tissue RNA - breast [nTPM]":"27.3","Tissue RNA - cerebellum [nTPM]":"69.4","Tissue RNA - cerebral cortex [nTPM]":"77.1","Tissue RNA - cervix [nTPM]":"30.8","Tissue RNA - choroid plexus [nTPM]":"44.6","Tissue RNA - colon [nTPM]":"31.4","Tissue RNA - duodenum [nTPM]":"9.7","Tissue RNA - endometrium 1 [nTPM]":"36.3","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"71.7","Tissue RNA - fallopian tube [nTPM]":"23.5","Tissue RNA - gallbladder [nTPM]":"23.3","Tissue RNA - heart muscle [nTPM]":"32.0","Tissue RNA - hippocampal formation [nTPM]":"57.2","Tissue RNA - hypothalamus [nTPM]":"67.9","Tissue RNA - kidney [nTPM]":"18.2","Tissue RNA - liver [nTPM]":"28.9","Tissue RNA - lung [nTPM]":"42.4","Tissue RNA - lymph node [nTPM]":"9.3","Tissue RNA - medulla oblongata [nTPM]":"76.7","Tissue RNA - midbrain [nTPM]":"77.2","Tissue RNA - ovary [nTPM]":"18.8","Tissue RNA - pancreas [nTPM]":"21.2","Tissue RNA - parathyroid gland [nTPM]":"32.4","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"23.1","Tissue RNA - pons [nTPM]":"67.9","Tissue RNA - prostate [nTPM]":"29.3","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"13.4","Tissue RNA - salivary gland [nTPM]":"28.1","Tissue RNA - seminal vesicle [nTPM]":"25.5","Tissue RNA - skeletal muscle [nTPM]":"13.9","Tissue RNA - skin 1 [nTPM]":"35.2","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"29.1","Tissue RNA - spinal cord [nTPM]":"63.9","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"82.6","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"25.6","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"10.1","Tissue RNA - urinary bladder [nTPM]":"32.7","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"52.4","Cell RNA - A-431 [nTPM]":"35.1","Cell RNA - A549 [nTPM]":"54.2","Cell RNA - AF22 [nTPM]":"32.0","Cell RNA - AN3-CA [nTPM]":"27.5","Cell RNA - ASC diff [nTPM]":"73.6","Cell RNA - ASC TERT1 [nTPM]":"28.3","Cell RNA - BEWO [nTPM]":"40.4","Cell RNA - BJ [nTPM]":"39.8","Cell RNA - BJ hTERT+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.1","Cell RNA - CACO-2 [nTPM]":"24.1","Cell RNA - CAPAN-2 [nTPM]":"73.2","Cell RNA - Daudi [nTPM]":"12.8","Cell RNA - EFO-21 [nTPM]":"43.6","Cell RNA - fHDF\/TERT166 [nTPM]":"43.3","Cell RNA - GAMG [nTPM]":"30.1","Cell RNA - HaCaT [nTPM]":"163.8","Cell RNA - HAP1 [nTPM]":"19.9","Cell RNA - HBEC3-KT [nTPM]":"87.5","Cell RNA - HBF TERT88 [nTPM]":"11.3","Cell RNA - HDLM-2 [nTPM]":"13.1","Cell RNA - HEK 293 [nTPM]":"16.4","Cell RNA - HEL [nTPM]":"11.5","Cell RNA - HeLa [nTPM]":"33.4","Cell RNA - Hep G2 [nTPM]":"29.2","Cell RNA - HHSteC [nTPM]":"49.8","Cell RNA - HL-60 [nTPM]":"13.8","Cell RNA - HMC-1 [nTPM]":"20.3","Cell RNA - HSkMC [nTPM]":"22.1","Cell RNA - hTCEpi [nTPM]":"60.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.7","Cell RNA - hTERT-HME1 [nTPM]":"50.8","Cell RNA - hTERT-RPE1 [nTPM]":"48.6","Cell RNA - HUVEC TERT2 [nTPM]":"84.1","Cell RNA - JURKAT [nTPM]":"17.5","Cell RNA - K-562 [nTPM]":"25.8","Cell RNA - Karpas-707 [nTPM]":"12.4","Cell RNA - LHCN-M2 [nTPM]":"31.8","Cell RNA - MCF7 [nTPM]":"30.3","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"13.2","Cell RNA - NTERA-2 [nTPM]":"95.9","Cell RNA - OE19 [nTPM]":"58.3","Cell RNA - PC-3 [nTPM]":"58.4","Cell RNA - REH [nTPM]":"21.4","Cell RNA - RH-30 [nTPM]":"37.0","Cell RNA - RPMI-8226 [nTPM]":"20.6","Cell RNA - RPTEC TERT1 [nTPM]":"37.9","Cell RNA - RT4 [nTPM]":"17.3","Cell RNA - SCLC-21H [nTPM]":"19.2","Cell RNA - SH-SY5Y [nTPM]":"39.9","Cell RNA - SiHa [nTPM]":"44.4","Cell RNA - SK-BR-3 [nTPM]":"27.3","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"19.9","Cell RNA - THP-1 [nTPM]":"10.2","Cell RNA - TIME [nTPM]":"149.4","Cell RNA - U-138 MG [nTPM]":"69.9","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"29.9","Cell RNA - U-251 MG [nTPM]":"58.8","Cell RNA - U-266\/70 [nTPM]":"14.4","Cell RNA - U-266\/84 [nTPM]":"36.5","Cell RNA - U-698 [nTPM]":"15.5","Cell RNA - U-87 MG [nTPM]":"38.7","Cell RNA - U-937 [nTPM]":"10.3","Cell RNA - WM-115 [nTPM]":"41.3","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"68.2","Brain RNA - basal ganglia [nTPM]":"69.4","Brain RNA - cerebellum [nTPM]":"69.4","Brain RNA - cerebral cortex [nTPM]":"77.1","Brain RNA - hippocampal formation [nTPM]":"57.2","Brain RNA - hypothalamus [nTPM]":"67.9","Brain RNA - medulla oblongata [nTPM]":"76.7","Brain RNA - midbrain [nTPM]":"77.2","Brain RNA - pons [nTPM]":"67.9","Brain RNA - spinal cord [nTPM]":"63.9","Brain RNA - thalamus [nTPM]":"82.6","Brain RNA - white matter [nTPM]":"52.4","Single Cell Type RNA - Adipocytes [nTPM]":"98.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.6","Single Cell Type RNA - Astrocytes [nTPM]":"57.1","Single Cell Type RNA - B-cells [nTPM]":"7.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"105.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"192.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"91.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"113.3","Single Cell Type RNA - Bipolar cells [nTPM]":"13.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"73.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - dendritic cells [nTPM]":"17.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"28.9","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.5","Single Cell Type RNA - Endothelial cells [nTPM]":"57.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.1","Single Cell Type RNA - Erythroid cells [nTPM]":"13.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.6","Single Cell Type RNA - Fibroblasts [nTPM]":"27.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.0","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"35.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.6","Single Cell Type RNA - Hepatocytes [nTPM]":"16.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"17.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.5","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"9.9","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"5.1","Single Cell Type RNA - Muller glia cells [nTPM]":"41.3","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"78.1","Single Cell Type RNA - Paneth cells [nTPM]":"23.0","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"207.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"33.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.2","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"8.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"91.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"145.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.8","Single Cell Type RNA - T-cells [nTPM]":"15.5","Single Cell Type RNA - Theca cells [nTPM]":"9.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.5","Single Cell Type RNA - Urothelial cells [nTPM]":"328.5"},{"Gene":"LRRC8B","Gene synonym":["KIAA0231","TA-LRRP"],"Ensembl":"ENSG00000197147","Gene description":"Leucine rich repeat containing 8 VRAC subunit B","Uniprot":["Q6P9F7"],"Chromosome":"1","Position":"89524829-89597861","Protein class":["Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"97.0","Excitatory neurons":"177.4","Inhibitory neurons":"197.3","Oligodendrocytes":"140.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"35.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017950"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 58: Brain - Synaptic function","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017950":"AB_1853346"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.15e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.99e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"14.6","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"8.1","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"5.0","Tissue RNA - heart muscle [nTPM]":"2.4","Tissue RNA - hippocampal formation [nTPM]":"13.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"6.6","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"12.9","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"1.1","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"5.8","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"3.6","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"15.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"13.0","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"3.8","Cell RNA - AN3-CA [nTPM]":"13.2","Cell RNA - ASC diff [nTPM]":"18.5","Cell RNA - ASC TERT1 [nTPM]":"10.8","Cell RNA - BEWO [nTPM]":"15.3","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"7.9","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"1.2","Cell RNA - EFO-21 [nTPM]":"4.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.9","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"6.7","Cell RNA - HAP1 [nTPM]":"35.6","Cell RNA - HBEC3-KT [nTPM]":"2.8","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"6.4","Cell RNA - HEK 293 [nTPM]":"6.3","Cell RNA - HEL [nTPM]":"28.9","Cell RNA - HeLa [nTPM]":"3.7","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"13.6","Cell RNA - HMC-1 [nTPM]":"17.7","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"11.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.5","Cell RNA - hTERT-HME1 [nTPM]":"5.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"18.7","Cell RNA - JURKAT [nTPM]":"10.6","Cell RNA - K-562 [nTPM]":"30.3","Cell RNA - Karpas-707 [nTPM]":"9.3","Cell RNA - LHCN-M2 [nTPM]":"2.1","Cell RNA - MCF7 [nTPM]":"7.9","Cell RNA - MOLT-4 [nTPM]":"5.3","Cell RNA - NB-4 [nTPM]":"6.2","Cell RNA - NTERA-2 [nTPM]":"20.7","Cell RNA - OE19 [nTPM]":"6.1","Cell RNA - PC-3 [nTPM]":"7.1","Cell RNA - REH [nTPM]":"13.0","Cell RNA - RH-30 [nTPM]":"1.7","Cell RNA - RPMI-8226 [nTPM]":"5.3","Cell RNA - RPTEC TERT1 [nTPM]":"4.5","Cell RNA - RT4 [nTPM]":"16.8","Cell RNA - SCLC-21H [nTPM]":"10.6","Cell RNA - SH-SY5Y [nTPM]":"17.5","Cell RNA - SiHa [nTPM]":"7.2","Cell RNA - SK-BR-3 [nTPM]":"18.3","Cell RNA - SK-MEL-30 [nTPM]":"12.7","Cell RNA - SuSa [nTPM]":"4.6","Cell RNA - T-47d [nTPM]":"10.7","Cell RNA - THP-1 [nTPM]":"6.1","Cell RNA - TIME [nTPM]":"6.0","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"4.1","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"4.7","Cell RNA - U-698 [nTPM]":"6.7","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"3.0","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"8.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"13.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.9","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"11.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"32.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"17.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.0","Single Cell Type RNA - Early spermatids [nTPM]":"97.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.9","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"177.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"13.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"6.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"197.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.8","Single Cell Type RNA - Langerhans cells [nTPM]":"17.3","Single Cell Type RNA - Late spermatids [nTPM]":"72.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"9.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"140.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.4","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"11.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.8","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"8.0","Single Cell Type RNA - Theca cells [nTPM]":"8.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.2","Single Cell Type RNA - Urothelial cells [nTPM]":"12.4"},{"Gene":"LRRC8C","Gene synonym":["AD158"],"Ensembl":"ENSG00000171488","Gene description":"Leucine rich repeat containing 8 VRAC subunit C","Uniprot":["Q8TDW0"],"Chromosome":"1","Position":"89633072-89769903","Protein class":["Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"73.5","Excitatory neurons":"73.6","Inhibitory neurons":"99.2","Microglial cells":"185.5","Oligodendrocytes":"85.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"8.9","monocytes":"6.6","T-cells":"11.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"THP-1":"41.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029347"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA029347":"AB_10601544"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.75e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.3","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"9.0","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"7.7","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"5.8","Tissue RNA - cervix [nTPM]":"3.2","Tissue RNA - choroid plexus [nTPM]":"11.4","Tissue RNA - colon [nTPM]":"3.2","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"4.1","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"12.2","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"3.7","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"2.0","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"3.8","Tissue RNA - smooth muscle [nTPM]":"15.8","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"8.0","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"6.2","Tissue RNA - vagina [nTPM]":"2.0","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"3.0","Cell RNA - AN3-CA [nTPM]":"2.7","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"19.3","Cell RNA - BJ hTERT+ [nTPM]":"21.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"6.0","Cell RNA - EFO-21 [nTPM]":"5.3","Cell RNA - fHDF\/TERT166 [nTPM]":"8.5","Cell RNA - GAMG [nTPM]":"14.9","Cell RNA - HaCaT [nTPM]":"13.1","Cell RNA - HAP1 [nTPM]":"10.1","Cell RNA - HBEC3-KT [nTPM]":"29.0","Cell RNA - HBF TERT88 [nTPM]":"20.9","Cell RNA - HDLM-2 [nTPM]":"14.8","Cell RNA - HEK 293 [nTPM]":"6.1","Cell RNA - HEL [nTPM]":"5.7","Cell RNA - HeLa [nTPM]":"2.9","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"7.4","Cell RNA - HL-60 [nTPM]":"26.6","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"5.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.8","Cell RNA - hTERT-HME1 [nTPM]":"10.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"35.6","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"3.9","Cell RNA - Karpas-707 [nTPM]":"7.9","Cell RNA - LHCN-M2 [nTPM]":"7.5","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"26.2","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"26.5","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"2.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"10.7","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"16.2","Cell RNA - SuSa [nTPM]":"4.7","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"41.3","Cell RNA - TIME [nTPM]":"29.9","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"7.3","Cell RNA - U-2197 [nTPM]":"5.3","Cell RNA - U-251 MG [nTPM]":"14.9","Cell RNA - U-266\/70 [nTPM]":"2.9","Cell RNA - U-266\/84 [nTPM]":"2.6","Cell RNA - U-698 [nTPM]":"3.1","Cell RNA - U-87 MG [nTPM]":"4.7","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"5.2","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"6.1","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"8.9","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"6.6","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"11.3","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"5.8","Brain RNA - hippocampal formation [nTPM]":"4.1","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"73.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"31.3","Single Cell Type RNA - B-cells [nTPM]":"7.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"45.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"24.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"36.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"47.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"73.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"8.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"58.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"99.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"29.5","Single Cell Type RNA - Langerhans cells [nTPM]":"36.9","Single Cell Type RNA - Late spermatids [nTPM]":"21.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"27.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"185.5","Single Cell Type RNA - monocytes [nTPM]":"21.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"85.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"20.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.9","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"27.1","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"LRRC8D","Gene synonym":["FLJ10470","LRRC5"],"Ensembl":"ENSG00000171492","Gene description":"Leucine rich repeat containing 8 VRAC subunit D","Uniprot":["Q7L1W4"],"Chromosome":"1","Position":"89821014-89936611","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"80.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"80.8","Oligodendrocyte precursor cells":"146.8","Oligodendrocytes":"346.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.52e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"26.9","Tissue RNA - amygdala [nTPM]":"25.1","Tissue RNA - appendix [nTPM]":"15.8","Tissue RNA - basal ganglia [nTPM]":"45.2","Tissue RNA - bone marrow [nTPM]":"14.2","Tissue RNA - breast [nTPM]":"12.9","Tissue RNA - cerebellum [nTPM]":"39.2","Tissue RNA - cerebral cortex [nTPM]":"37.0","Tissue RNA - cervix [nTPM]":"12.1","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"17.9","Tissue RNA - duodenum [nTPM]":"19.0","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"7.8","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"30.6","Tissue RNA - hypothalamus [nTPM]":"30.2","Tissue RNA - kidney [nTPM]":"25.9","Tissue RNA - liver [nTPM]":"23.5","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"24.9","Tissue RNA - medulla oblongata [nTPM]":"43.3","Tissue RNA - midbrain [nTPM]":"40.3","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"41.3","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"18.2","Tissue RNA - retina [nTPM]":"12.0","Tissue RNA - salivary gland [nTPM]":"24.5","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"8.7","Tissue RNA - skin 1 [nTPM]":"5.6","Tissue RNA - small intestine [nTPM]":"18.0","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"39.7","Tissue RNA - spleen [nTPM]":"23.9","Tissue RNA - stomach 1 [nTPM]":"11.5","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"36.5","Tissue RNA - thymus [nTPM]":"27.7","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"20.4","Tissue RNA - urinary bladder [nTPM]":"11.2","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"80.4","Cell RNA - A-431 [nTPM]":"73.5","Cell RNA - A549 [nTPM]":"47.0","Cell RNA - AF22 [nTPM]":"18.8","Cell RNA - AN3-CA [nTPM]":"44.5","Cell RNA - ASC diff [nTPM]":"32.9","Cell RNA - ASC TERT1 [nTPM]":"27.7","Cell RNA - BEWO [nTPM]":"63.5","Cell RNA - BJ [nTPM]":"49.1","Cell RNA - BJ hTERT+ [nTPM]":"73.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.1","Cell RNA - CACO-2 [nTPM]":"20.2","Cell RNA - CAPAN-2 [nTPM]":"18.3","Cell RNA - Daudi [nTPM]":"57.7","Cell RNA - EFO-21 [nTPM]":"54.4","Cell RNA - fHDF\/TERT166 [nTPM]":"82.1","Cell RNA - GAMG [nTPM]":"31.0","Cell RNA - HaCaT [nTPM]":"93.7","Cell RNA - HAP1 [nTPM]":"43.6","Cell RNA - HBEC3-KT [nTPM]":"58.9","Cell RNA - HBF TERT88 [nTPM]":"34.4","Cell RNA - HDLM-2 [nTPM]":"45.3","Cell RNA - HEK 293 [nTPM]":"24.1","Cell RNA - HEL [nTPM]":"67.8","Cell RNA - HeLa [nTPM]":"40.4","Cell RNA - Hep G2 [nTPM]":"43.2","Cell RNA - HHSteC [nTPM]":"64.2","Cell RNA - HL-60 [nTPM]":"78.2","Cell RNA - HMC-1 [nTPM]":"20.5","Cell RNA - HSkMC [nTPM]":"17.4","Cell RNA - hTCEpi [nTPM]":"48.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.3","Cell RNA - hTERT-HME1 [nTPM]":"50.3","Cell RNA - hTERT-RPE1 [nTPM]":"37.6","Cell RNA - HUVEC TERT2 [nTPM]":"47.1","Cell RNA - JURKAT [nTPM]":"32.8","Cell RNA - K-562 [nTPM]":"37.6","Cell RNA - Karpas-707 [nTPM]":"17.7","Cell RNA - LHCN-M2 [nTPM]":"30.1","Cell RNA - MCF7 [nTPM]":"22.0","Cell RNA - MOLT-4 [nTPM]":"32.5","Cell RNA - NB-4 [nTPM]":"50.4","Cell RNA - NTERA-2 [nTPM]":"32.6","Cell RNA - OE19 [nTPM]":"16.4","Cell RNA - PC-3 [nTPM]":"42.6","Cell RNA - REH [nTPM]":"43.6","Cell RNA - RH-30 [nTPM]":"27.3","Cell RNA - RPMI-8226 [nTPM]":"41.5","Cell RNA - RPTEC TERT1 [nTPM]":"69.2","Cell RNA - RT4 [nTPM]":"25.7","Cell RNA - SCLC-21H [nTPM]":"35.0","Cell RNA - SH-SY5Y [nTPM]":"24.4","Cell RNA - SiHa [nTPM]":"61.0","Cell RNA - SK-BR-3 [nTPM]":"62.4","Cell RNA - SK-MEL-30 [nTPM]":"137.8","Cell RNA - SuSa [nTPM]":"32.4","Cell RNA - T-47d [nTPM]":"15.0","Cell RNA - THP-1 [nTPM]":"76.4","Cell RNA - TIME [nTPM]":"21.0","Cell RNA - U-138 MG [nTPM]":"29.1","Cell RNA - U-2 OS [nTPM]":"9.9","Cell RNA - U-2197 [nTPM]":"60.0","Cell RNA - U-251 MG [nTPM]":"37.6","Cell RNA - U-266\/70 [nTPM]":"21.4","Cell RNA - U-266\/84 [nTPM]":"39.5","Cell RNA - U-698 [nTPM]":"34.7","Cell RNA - U-87 MG [nTPM]":"11.3","Cell RNA - U-937 [nTPM]":"97.0","Cell RNA - WM-115 [nTPM]":"26.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"8.9","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"7.0","Blood RNA - intermediate monocyte [nTPM]":"10.4","Blood RNA - MAIT T-cell [nTPM]":"11.6","Blood RNA - memory B-cell [nTPM]":"6.9","Blood RNA - memory CD4 T-cell [nTPM]":"16.0","Blood RNA - memory CD8 T-cell [nTPM]":"8.5","Blood RNA - myeloid DC [nTPM]":"8.1","Blood RNA - naive B-cell [nTPM]":"5.6","Blood RNA - naive CD4 T-cell [nTPM]":"15.2","Blood RNA - naive CD8 T-cell [nTPM]":"11.5","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"13.1","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"9.4","Blood RNA - T-reg [nTPM]":"17.4","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"25.1","Brain RNA - basal ganglia [nTPM]":"45.2","Brain RNA - cerebellum [nTPM]":"39.2","Brain RNA - cerebral cortex [nTPM]":"37.0","Brain RNA - hippocampal formation [nTPM]":"30.6","Brain RNA - hypothalamus [nTPM]":"30.2","Brain RNA - medulla oblongata [nTPM]":"43.3","Brain RNA - midbrain [nTPM]":"40.3","Brain RNA - pons [nTPM]":"41.3","Brain RNA - spinal cord [nTPM]":"39.7","Brain RNA - thalamus [nTPM]":"36.5","Brain RNA - white matter [nTPM]":"80.4","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"35.3","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"17.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"66.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.9","Single Cell Type RNA - Fibroblasts [nTPM]":"3.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"30.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"80.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"19.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"68.4","Single Cell Type RNA - monocytes [nTPM]":"36.3","Single Cell Type RNA - Muller glia cells [nTPM]":"6.3","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"146.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"346.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"11.3","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"11.0","Single Cell Type RNA - Theca cells [nTPM]":"22.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"LRRC8E","Gene synonym":["FLJ23420"],"Ensembl":"ENSG00000171017","Gene description":"Leucine rich repeat containing 8 VRAC subunit E","Uniprot":["Q6NSJ5"],"Chromosome":"19","Position":"7888505-7902021","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"9.6","Glandular and luminal cells":"13.0","Squamous epithelial cells":"11.6","Suprabasal keratinocytes":"11.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-87 MG":"36.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020466"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA020466":"AB_1853352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"1.9","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"1.0","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"0.9","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"1.9","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"0.7","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"10.6","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"2.0","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"6.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"5.6","Cell RNA - BEWO [nTPM]":"3.5","Cell RNA - BJ [nTPM]":"10.1","Cell RNA - BJ hTERT+ [nTPM]":"8.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.3","Cell RNA - CACO-2 [nTPM]":"7.7","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"7.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"22.5","Cell RNA - HaCaT [nTPM]":"18.3","Cell RNA - HAP1 [nTPM]":"7.7","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"14.9","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"8.5","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"3.1","Cell RNA - Hep G2 [nTPM]":"8.2","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"9.1","Cell RNA - hTCEpi [nTPM]":"13.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.5","Cell RNA - hTERT-HME1 [nTPM]":"7.8","Cell RNA - hTERT-RPE1 [nTPM]":"21.2","Cell RNA - HUVEC TERT2 [nTPM]":"2.0","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"6.5","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"11.9","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"4.3","Cell RNA - PC-3 [nTPM]":"21.9","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"12.0","Cell RNA - RT4 [nTPM]":"21.3","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"7.6","Cell RNA - SK-BR-3 [nTPM]":"9.6","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"12.8","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"8.7","Cell RNA - U-2197 [nTPM]":"13.2","Cell RNA - U-251 MG [nTPM]":"5.8","Cell RNA - U-266\/70 [nTPM]":"1.5","Cell RNA - U-266\/84 [nTPM]":"2.9","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"36.4","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"1.0","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.3","Single Cell Type RNA - Urothelial cells [nTPM]":"5.9"},{"Gene":"LYST","Gene synonym":["CHS","CHS1"],"Ensembl":"ENSG00000143669","Gene description":"Lysosomal trafficking regulator","Uniprot":["Q99698"],"Chromosome":"1","Position":"235661041-235883640","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Phagocytosis","Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"31.3","retina":"27.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"277.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"11.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"12.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"12.2","monocytes":"6.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"30.8","SK-MEL-30":"27.1","THP-1":"99.5","U-937":"38.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053366","HPA055725"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Centriolar satellite"],"Antibody RRID":{"HPA053366":"AB_2682129","HPA055725":"AB_2682898"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.27e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"2.7","Tissue RNA - bone marrow [nTPM]":"31.3","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"10.1","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"4.5","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"3.9","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"5.5","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"2.5","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"27.9","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"4.4","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"7.7","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"25.7","Tissue RNA - thyroid gland [nTPM]":"6.4","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"6.5","Tissue RNA - urinary bladder [nTPM]":"5.7","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"8.6","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"2.0","Cell RNA - ASC diff [nTPM]":"12.7","Cell RNA - ASC TERT1 [nTPM]":"14.4","Cell RNA - BEWO [nTPM]":"1.3","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"6.8","Cell RNA - GAMG [nTPM]":"7.7","Cell RNA - HaCaT [nTPM]":"4.1","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"2.9","Cell RNA - HDLM-2 [nTPM]":"30.8","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"2.8","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"2.3","Cell RNA - HL-60 [nTPM]":"4.2","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"7.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.0","Cell RNA - hTERT-HME1 [nTPM]":"10.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.8","Cell RNA - HUVEC TERT2 [nTPM]":"2.8","Cell RNA - JURKAT [nTPM]":"1.3","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.7","Cell RNA - LHCN-M2 [nTPM]":"2.6","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"5.3","Cell RNA - NB-4 [nTPM]":"8.7","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"9.2","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"27.1","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"99.5","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"2.8","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"2.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"4.1","Cell RNA - U-937 [nTPM]":"38.0","Cell RNA - WM-115 [nTPM]":"7.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"5.7","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"12.2","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"6.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.7","Brain RNA - cerebellum [nTPM]":"10.1","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.5","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"66.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"41.1","Single Cell Type RNA - Astrocytes [nTPM]":"71.2","Single Cell Type RNA - B-cells [nTPM]":"70.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"71.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"89.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"67.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"28.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - dendritic cells [nTPM]":"77.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"24.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.8","Single Cell Type RNA - Endothelial cells [nTPM]":"51.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"21.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"151.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.0","Single Cell Type RNA - Fibroblasts [nTPM]":"27.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.4","Single Cell Type RNA - granulocytes [nTPM]":"112.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"15.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.9","Single Cell Type RNA - Horizontal cells [nTPM]":"52.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"155.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"65.6","Single Cell Type RNA - Langerhans cells [nTPM]":"81.3","Single Cell Type RNA - Late spermatids [nTPM]":"17.7","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"111.4","Single Cell Type RNA - Melanocytes [nTPM]":"120.9","Single Cell Type RNA - Microglial cells [nTPM]":"159.3","Single Cell Type RNA - monocytes [nTPM]":"277.4","Single Cell Type RNA - Muller glia cells [nTPM]":"25.6","Single Cell Type RNA - NK-cells [nTPM]":"88.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"112.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"81.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.6","Single Cell Type RNA - Paneth cells [nTPM]":"24.2","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"37.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"56.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"162.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.7","Single Cell Type RNA - Spermatocytes [nTPM]":"93.3","Single Cell Type RNA - Spermatogonia [nTPM]":"28.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"65.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"71.3","Single Cell Type RNA - Theca cells [nTPM]":"13.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"98.5"},{"Gene":"MALT1","Gene synonym":["MLT","PCASP1"],"Ensembl":"ENSG00000172175","Gene description":"MALT1 paracaspase","Uniprot":["Q9UDY8"],"Chromosome":"18","Position":"58671465-58754477","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Immunity","Ubl conjugation pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPTEC TERT1":"88.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004494","HPA048432"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004494":"AB_627909","HPA048432":"AB_2680389"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"10.5","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"3.6","Tissue RNA - cervix [nTPM]":"7.7","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"5.4","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"12.5","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"5.4","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"6.9","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"21.1","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"4.0","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"11.5","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"8.3","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"23.1","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"11.4","Cell RNA - A549 [nTPM]":"16.0","Cell RNA - AF22 [nTPM]":"16.8","Cell RNA - AN3-CA [nTPM]":"5.2","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"6.7","Cell RNA - BEWO [nTPM]":"9.2","Cell RNA - BJ [nTPM]":"19.7","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"13.5","Cell RNA - Daudi [nTPM]":"27.0","Cell RNA - EFO-21 [nTPM]":"10.3","Cell RNA - fHDF\/TERT166 [nTPM]":"24.0","Cell RNA - GAMG [nTPM]":"11.1","Cell RNA - HaCaT [nTPM]":"12.0","Cell RNA - HAP1 [nTPM]":"10.8","Cell RNA - HBEC3-KT [nTPM]":"7.6","Cell RNA - HBF TERT88 [nTPM]":"20.8","Cell RNA - HDLM-2 [nTPM]":"17.0","Cell RNA - HEK 293 [nTPM]":"6.8","Cell RNA - HEL [nTPM]":"9.7","Cell RNA - HeLa [nTPM]":"9.0","Cell RNA - Hep G2 [nTPM]":"21.8","Cell RNA - HHSteC [nTPM]":"4.0","Cell RNA - HL-60 [nTPM]":"20.1","Cell RNA - HMC-1 [nTPM]":"11.4","Cell RNA - HSkMC [nTPM]":"4.0","Cell RNA - hTCEpi [nTPM]":"12.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.8","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"3.4","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"15.3","Cell RNA - Karpas-707 [nTPM]":"42.3","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"4.7","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"6.3","Cell RNA - OE19 [nTPM]":"4.1","Cell RNA - PC-3 [nTPM]":"7.1","Cell RNA - REH [nTPM]":"14.8","Cell RNA - RH-30 [nTPM]":"11.5","Cell RNA - RPMI-8226 [nTPM]":"19.7","Cell RNA - RPTEC TERT1 [nTPM]":"88.9","Cell RNA - RT4 [nTPM]":"2.8","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"11.7","Cell RNA - SK-BR-3 [nTPM]":"6.0","Cell RNA - SK-MEL-30 [nTPM]":"9.3","Cell RNA - SuSa [nTPM]":"12.0","Cell RNA - T-47d [nTPM]":"5.1","Cell RNA - THP-1 [nTPM]":"12.2","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"22.6","Cell RNA - U-2 OS [nTPM]":"9.1","Cell RNA - U-2197 [nTPM]":"7.1","Cell RNA - U-251 MG [nTPM]":"20.8","Cell RNA - U-266\/70 [nTPM]":"38.5","Cell RNA - U-266\/84 [nTPM]":"54.4","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"10.6","Cell RNA - U-937 [nTPM]":"15.6","Cell RNA - WM-115 [nTPM]":"9.9","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"3.6","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"35.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.2","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"67.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"7.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"85.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - dendritic cells [nTPM]":"53.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.6","Single Cell Type RNA - Early spermatids [nTPM]":"12.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.5","Single Cell Type RNA - Endothelial cells [nTPM]":"31.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.7","Single Cell Type RNA - granulocytes [nTPM]":"31.7","Single Cell Type RNA - Granulosa cells [nTPM]":"28.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.8","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"96.5","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"55.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"79.5","Single Cell Type RNA - Muller glia cells [nTPM]":"26.2","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"52.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"42.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"40.1","Single Cell Type RNA - Spermatogonia [nTPM]":"35.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"55.2","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.7","Single Cell Type RNA - Urothelial cells [nTPM]":"38.1"},{"Gene":"MASP2","Gene synonym":["MASP1P1"],"Ensembl":"ENSG00000009724","Gene description":"Mannan binding lectin serine peptidase 2","Uniprot":["O00187"],"Chromosome":"1","Position":"11026523-11047239","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins"],"Biological process":["Complement pathway","Immunity","Innate immunity"],"Molecular function":["Hydrolase","Protease","Serine protease"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"64","RNA tissue specific nTPM":{"liver":"476.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"52","RNA single cell type specific nTPM":{"Hepatocytes":"658.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"71","RNA cancer specific FPKM":{"liver cancer":"41.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"9","RNA brain regional specific nTPM":{"cerebellum":"6.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Hep G2":"16.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029313","HPA029314"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":340000000,"Blood concentration - Conc. blood MS [pg\/L]":"820000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 62: Liver - Hemostasis","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA029313":"AB_10669654","HPA029314":"AB_10670029"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.60e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"7.4","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"2.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"476.5","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"1.6","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"6.9","Tissue RNA - salivary gland [nTPM]":"2.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"5.3","Tissue RNA - small intestine [nTPM]":"3.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"2.6","Cell RNA - AN3-CA [nTPM]":"1.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"16.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"1.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.7","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"0.6","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.5","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"658.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"MBL2","Gene synonym":["COLEC1","MBL"],"Ensembl":"ENSG00000165471","Gene description":"Mannose binding lectin 2","Uniprot":["P11226"],"Chromosome":"10","Position":"52765380-52772784","Protein class":["Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement activation lectin pathway","Complement pathway","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"2810","RNA tissue specific nTPM":{"liver":"280.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"66","RNA single cell type specific nTPM":{"Hepatocytes":"238.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"275","RNA cancer specific FPKM":{"liver cancer":"22.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Hep G2":"2.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"11","RNA pig brain regional specific nTPM":{"basal ganglia":"1.1"},"Antibody":["HPA002027","CAB016782"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1220000000,"Blood concentration - Conc. blood MS [pg\/L]":"1900000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016782":null,"HPA002027":"AB_1079324"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"280.9","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"238.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MCM4","Gene synonym":["CDC21","CDC54","hCdc21","MGC33310","P1-Cdc21"],"Ensembl":"ENSG00000104738","Gene description":"Minichromosome maintenance complex component 4","Uniprot":["P33991"],"Chromosome":"8","Position":"47960185-47978160","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"63.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"153.2","Erythroid cells":"60.8","Late spermatids":"77.9","Spermatocytes":"65.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004497","HPA004873","HPA031052"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004497":"AB_627916","HPA004873":"AB_1079337","HPA031052":"AB_2673712"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.19e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.84e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.15e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.38e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.5","Tissue RNA - adrenal gland [nTPM]":"8.8","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"21.7","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"63.2","Tissue RNA - breast [nTPM]":"16.0","Tissue RNA - cerebellum [nTPM]":"5.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"7.7","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"17.7","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"22.4","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"14.5","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"38.7","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"7.1","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"18.3","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"21.3","Tissue RNA - retina [nTPM]":"12.3","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"4.9","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"4.2","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"41.6","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"47.0","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"15.8","Tissue RNA - tonsil [nTPM]":"41.8","Tissue RNA - urinary bladder [nTPM]":"11.8","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"5.2","Cell RNA - A-431 [nTPM]":"184.0","Cell RNA - A549 [nTPM]":"139.6","Cell RNA - AF22 [nTPM]":"188.1","Cell RNA - AN3-CA [nTPM]":"83.2","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"36.6","Cell RNA - BEWO [nTPM]":"102.8","Cell RNA - BJ [nTPM]":"122.6","Cell RNA - BJ hTERT+ [nTPM]":"99.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"178.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"190.3","Cell RNA - CACO-2 [nTPM]":"156.6","Cell RNA - CAPAN-2 [nTPM]":"181.1","Cell RNA - Daudi [nTPM]":"229.8","Cell RNA - EFO-21 [nTPM]":"70.3","Cell RNA - fHDF\/TERT166 [nTPM]":"72.1","Cell RNA - GAMG [nTPM]":"119.2","Cell RNA - HaCaT [nTPM]":"143.2","Cell RNA - HAP1 [nTPM]":"278.7","Cell RNA - HBEC3-KT [nTPM]":"128.2","Cell RNA - HBF TERT88 [nTPM]":"199.8","Cell RNA - HDLM-2 [nTPM]":"64.2","Cell RNA - HEK 293 [nTPM]":"190.4","Cell RNA - HEL [nTPM]":"371.8","Cell RNA - HeLa [nTPM]":"133.3","Cell RNA - Hep G2 [nTPM]":"169.2","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"189.7","Cell RNA - HMC-1 [nTPM]":"82.0","Cell RNA - HSkMC [nTPM]":"20.3","Cell RNA - hTCEpi [nTPM]":"24.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"147.8","Cell RNA - hTERT-HME1 [nTPM]":"54.3","Cell RNA - hTERT-RPE1 [nTPM]":"28.6","Cell RNA - HUVEC TERT2 [nTPM]":"72.0","Cell RNA - JURKAT [nTPM]":"136.8","Cell RNA - K-562 [nTPM]":"216.2","Cell RNA - Karpas-707 [nTPM]":"167.0","Cell RNA - LHCN-M2 [nTPM]":"129.9","Cell RNA - MCF7 [nTPM]":"155.6","Cell RNA - MOLT-4 [nTPM]":"435.5","Cell RNA - NB-4 [nTPM]":"141.5","Cell RNA - NTERA-2 [nTPM]":"241.2","Cell RNA - OE19 [nTPM]":"246.5","Cell RNA - PC-3 [nTPM]":"54.2","Cell RNA - REH [nTPM]":"266.6","Cell RNA - RH-30 [nTPM]":"159.6","Cell RNA - RPMI-8226 [nTPM]":"139.2","Cell RNA - RPTEC TERT1 [nTPM]":"64.9","Cell RNA - RT4 [nTPM]":"168.1","Cell RNA - SCLC-21H [nTPM]":"209.0","Cell RNA - SH-SY5Y [nTPM]":"97.8","Cell RNA - SiHa [nTPM]":"325.6","Cell RNA - SK-BR-3 [nTPM]":"133.6","Cell RNA - SK-MEL-30 [nTPM]":"46.3","Cell RNA - SuSa [nTPM]":"117.7","Cell RNA - T-47d [nTPM]":"154.9","Cell RNA - THP-1 [nTPM]":"110.5","Cell RNA - TIME [nTPM]":"45.1","Cell RNA - U-138 MG [nTPM]":"138.1","Cell RNA - U-2 OS [nTPM]":"125.4","Cell RNA - U-2197 [nTPM]":"144.5","Cell RNA - U-251 MG [nTPM]":"131.9","Cell RNA - U-266\/70 [nTPM]":"54.7","Cell RNA - U-266\/84 [nTPM]":"104.6","Cell RNA - U-698 [nTPM]":"347.2","Cell RNA - U-87 MG [nTPM]":"114.8","Cell RNA - U-937 [nTPM]":"185.7","Cell RNA - WM-115 [nTPM]":"131.5","Blood RNA - basophil [nTPM]":"2.3","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"3.5","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"10.2","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"5.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"4.2","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"5.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.3","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"6.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"8.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.7","Single Cell Type RNA - dendritic cells [nTPM]":"5.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.0","Single Cell Type RNA - Early spermatids [nTPM]":"153.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"60.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.2","Single Cell Type RNA - Fibroblasts [nTPM]":"10.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.3","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"77.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"7.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"2.4","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.5","Single Cell Type RNA - Paneth cells [nTPM]":"4.8","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"22.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.4","Single Cell Type RNA - Spermatocytes [nTPM]":"65.8","Single Cell Type RNA - Spermatogonia [nTPM]":"39.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"29.8","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"11.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"MLPH","Gene synonym":["exophilin-3","l(1)-3Rk","l1Rk3","ln","Slac-2a"],"Ensembl":"ENSG00000115648","Gene description":"Melanophilin","Uniprot":["Q9BV36"],"Chromosome":"2","Position":"237485428-237555322","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"135.9","salivary gland":"122.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"125.0","Alveolar cells type 2":"389.7","Gastric mucus-secreting cells":"251.8","granulocytes":"187.3","Intestinal goblet cells":"189.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"LHCN-M2":"142.9","MCF7":"255.4","SK-BR-3":"234.5","SK-MEL-30":"182.2","U-87 MG":"236.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA014685"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014685":"AB_1853997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.14e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Tissue RNA - adipose tissue [nTPM]":"13.2","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"2.4","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"56.9","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"69.3","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"20.4","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"18.1","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"18.0","Tissue RNA - gallbladder [nTPM]":"31.0","Tissue RNA - heart muscle [nTPM]":"69.2","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"4.3","Tissue RNA - liver [nTPM]":"39.0","Tissue RNA - lung [nTPM]":"62.7","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"16.1","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"135.9","Tissue RNA - rectum [nTPM]":"21.7","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"122.0","Tissue RNA - seminal vesicle [nTPM]":"13.0","Tissue RNA - skeletal muscle [nTPM]":"6.6","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"15.2","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"98.1","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.9","Tissue RNA - thyroid gland [nTPM]":"39.9","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"22.1","Tissue RNA - vagina [nTPM]":"21.9","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"133.7","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"58.5","Cell RNA - ASC TERT1 [nTPM]":"39.5","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"26.8","Cell RNA - BJ hTERT+ [nTPM]":"31.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.5","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"101.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"49.6","Cell RNA - GAMG [nTPM]":"51.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.9","Cell RNA - HBF TERT88 [nTPM]":"13.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"23.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"48.1","Cell RNA - hTCEpi [nTPM]":"14.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.4","Cell RNA - hTERT-HME1 [nTPM]":"56.2","Cell RNA - hTERT-RPE1 [nTPM]":"75.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"142.9","Cell RNA - MCF7 [nTPM]":"255.4","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"105.4","Cell RNA - PC-3 [nTPM]":"77.1","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"234.5","Cell RNA - SK-MEL-30 [nTPM]":"182.2","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"61.5","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"26.8","Cell RNA - U-138 MG [nTPM]":"80.1","Cell RNA - U-2 OS [nTPM]":"2.3","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"38.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"236.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"63.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"12.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"125.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"389.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"95.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"59.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"63.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"52.9","Single Cell Type RNA - Club cells [nTPM]":"64.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"41.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"251.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.5","Single Cell Type RNA - granulocytes [nTPM]":"187.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"28.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"189.0","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"7.4","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.1","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"48.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"6.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.5","Single Cell Type RNA - Urothelial cells [nTPM]":"38.6"},{"Gene":"MPO","Gene synonym":[],"Ensembl":"ENSG00000005381","Gene description":"Myeloperoxidase","Uniprot":["P05164"],"Chromosome":"17","Position":"58269855-58280935","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Hydrogen peroxide"],"Molecular function":["Oxidoreductase","Peroxidase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"61","RNA tissue specific nTPM":{"bone marrow":"4023.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"30","RNA single cell type specific nTPM":{"Erythroid cells":"87.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"stomach cancer":"1.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"6.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"94","RNA cell line specific nTPM":{"HL-60":"3517.4","NB-4":"4589.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000059","HPA021147","HPA061464"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":576000000,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB000059":"AB_2335676","HPA021147":"AB_1854083","HPA061464":"AB_2684531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"4023.1","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"8.4","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"66.3","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"4.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"21.7","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"3517.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4589.9","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"5.3","Cell RNA - RH-30 [nTPM]":"3.2","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"43.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"6.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"7.5","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"87.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MRE11","Gene synonym":["ATLD","MRE11A"],"Ensembl":"ENSG00000020922","Gene description":"MRE11 homolog, double strand break repair nuclease","Uniprot":["P49959"],"Chromosome":"11","Position":"94415570-94493885","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction","Meiosis"],"Molecular function":["Endonuclease","Exonuclease","Hydrolase","Nuclease"],"Disease involvement":["Cancer-related genes","Ciliopathy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"28.9","Cytotrophoblasts":"39.2","Granulosa cells":"34.1","Syncytiotrophoblasts":"28.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002691","CAB004081"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004081":"AB_2145100","HPA002691":"AB_1079409"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.14e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"6.1","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"11.7","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"22.6","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"8.8","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"8.9","Tissue RNA - esophagus [nTPM]":"7.1","Tissue RNA - fallopian tube [nTPM]":"7.9","Tissue RNA - gallbladder [nTPM]":"7.3","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"6.0","Tissue RNA - liver [nTPM]":"6.4","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"11.1","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"4.4","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"5.4","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"21.5","Cell RNA - A549 [nTPM]":"21.5","Cell RNA - AF22 [nTPM]":"39.9","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"13.1","Cell RNA - ASC TERT1 [nTPM]":"18.2","Cell RNA - BEWO [nTPM]":"22.8","Cell RNA - BJ [nTPM]":"29.4","Cell RNA - BJ hTERT+ [nTPM]":"19.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.6","Cell RNA - CACO-2 [nTPM]":"39.4","Cell RNA - CAPAN-2 [nTPM]":"43.3","Cell RNA - Daudi [nTPM]":"55.8","Cell RNA - EFO-21 [nTPM]":"47.0","Cell RNA - fHDF\/TERT166 [nTPM]":"15.3","Cell RNA - GAMG [nTPM]":"32.5","Cell RNA - HaCaT [nTPM]":"40.1","Cell RNA - HAP1 [nTPM]":"33.7","Cell RNA - HBEC3-KT [nTPM]":"22.1","Cell RNA - HBF TERT88 [nTPM]":"34.1","Cell RNA - HDLM-2 [nTPM]":"37.5","Cell RNA - HEK 293 [nTPM]":"20.0","Cell RNA - HEL [nTPM]":"48.7","Cell RNA - HeLa [nTPM]":"31.5","Cell RNA - Hep G2 [nTPM]":"22.7","Cell RNA - HHSteC [nTPM]":"6.0","Cell RNA - HL-60 [nTPM]":"32.7","Cell RNA - HMC-1 [nTPM]":"33.6","Cell RNA - HSkMC [nTPM]":"12.8","Cell RNA - hTCEpi [nTPM]":"13.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.7","Cell RNA - hTERT-HME1 [nTPM]":"21.0","Cell RNA - hTERT-RPE1 [nTPM]":"11.7","Cell RNA - HUVEC TERT2 [nTPM]":"23.0","Cell RNA - JURKAT [nTPM]":"26.8","Cell RNA - K-562 [nTPM]":"34.9","Cell RNA - Karpas-707 [nTPM]":"35.6","Cell RNA - LHCN-M2 [nTPM]":"20.9","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"33.2","Cell RNA - NB-4 [nTPM]":"30.5","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"49.3","Cell RNA - PC-3 [nTPM]":"23.3","Cell RNA - REH [nTPM]":"29.0","Cell RNA - RH-30 [nTPM]":"35.3","Cell RNA - RPMI-8226 [nTPM]":"28.1","Cell RNA - RPTEC TERT1 [nTPM]":"16.8","Cell RNA - RT4 [nTPM]":"29.6","Cell RNA - SCLC-21H [nTPM]":"14.1","Cell RNA - SH-SY5Y [nTPM]":"19.8","Cell RNA - SiHa [nTPM]":"40.6","Cell RNA - SK-BR-3 [nTPM]":"26.0","Cell RNA - SK-MEL-30 [nTPM]":"8.6","Cell RNA - SuSa [nTPM]":"33.2","Cell RNA - T-47d [nTPM]":"43.4","Cell RNA - THP-1 [nTPM]":"19.3","Cell RNA - TIME [nTPM]":"16.9","Cell RNA - U-138 MG [nTPM]":"38.7","Cell RNA - U-2 OS [nTPM]":"28.6","Cell RNA - U-2197 [nTPM]":"33.9","Cell RNA - U-251 MG [nTPM]":"21.5","Cell RNA - U-266\/70 [nTPM]":"8.8","Cell RNA - U-266\/84 [nTPM]":"33.2","Cell RNA - U-698 [nTPM]":"54.4","Cell RNA - U-87 MG [nTPM]":"10.4","Cell RNA - U-937 [nTPM]":"50.3","Cell RNA - WM-115 [nTPM]":"31.5","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"8.0","Blood RNA - eosinophil [nTPM]":"6.5","Blood RNA - gdT-cell [nTPM]":"8.2","Blood RNA - intermediate monocyte [nTPM]":"10.0","Blood RNA - MAIT T-cell [nTPM]":"8.3","Blood RNA - memory B-cell [nTPM]":"6.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.0","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"11.6","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.1","Blood RNA - naive CD8 T-cell [nTPM]":"8.4","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"8.7","Blood RNA - T-reg [nTPM]":"8.8","Blood RNA - total PBMC [nTPM]":"6.7","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"4.4","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"23.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.2","Single Cell Type RNA - dendritic cells [nTPM]":"20.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"8.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.8","Single Cell Type RNA - Fibroblasts [nTPM]":"8.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.3","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"34.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"10.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.0","Single Cell Type RNA - T-cells [nTPM]":"7.2","Single Cell Type RNA - Theca cells [nTPM]":"16.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MS4A1","Gene synonym":["B1","Bp35","CD20","MS4A2"],"Ensembl":"ENSG00000156738","Gene description":"Membrane spanning 4-domains A1","Uniprot":["P11836"],"Chromosome":"11","Position":"60455846-60470752","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["B-cell activation"],"Molecular function":null,"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"673.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"35","RNA single cell type specific nTPM":{"B-cells":"970.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"96","RNA blood cell specific nTPM":{"memory B-cell":"625.4","naive B-cell":"627.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"96","RNA blood lineage specific nTPM":{"B-cells":"627.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"26","RNA cell line specific nTPM":{"Daudi":"731.3","U-698":"364.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000015","HPA014341","HPA014391"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000015":"AB_2282030","HPA014341":"AB_1846265","HPA014391":"AB_1846264"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.34e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.6","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"149.7","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"19.1","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"2.2","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"500.4","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"7.3","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"10.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"8.9","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"123.5","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"253.8","Tissue RNA - stomach 1 [nTPM]":"18.4","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"50.6","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"673.3","Tissue RNA - urinary bladder [nTPM]":"16.3","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"731.3","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"21.3","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"364.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"625.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"5.5","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"627.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"6.5","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"32.1","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"970.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"14.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"27.3","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MYD88","Gene synonym":[],"Ensembl":"ENSG00000172936","Gene description":"MYD88 innate immune signal transduction adaptor","Uniprot":["Q99836"],"Chromosome":"3","Position":"38138478-38143022","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"75.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"172.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009104"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles","Mitochondria"],"Antibody RRID":{"CAB009104":"AB_2146724"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.1","Tissue RNA - adrenal gland [nTPM]":"14.2","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"43.5","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"51.8","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"8.0","Tissue RNA - colon [nTPM]":"30.3","Tissue RNA - duodenum [nTPM]":"32.2","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"36.6","Tissue RNA - fallopian tube [nTPM]":"14.4","Tissue RNA - gallbladder [nTPM]":"23.5","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"7.7","Tissue RNA - kidney [nTPM]":"13.7","Tissue RNA - liver [nTPM]":"61.1","Tissue RNA - lung [nTPM]":"42.6","Tissue RNA - lymph node [nTPM]":"35.2","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"11.4","Tissue RNA - pancreas [nTPM]":"11.6","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"22.6","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"31.7","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"18.0","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"17.7","Tissue RNA - small intestine [nTPM]":"32.2","Tissue RNA - smooth muscle [nTPM]":"24.5","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"40.7","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"38.3","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"41.6","Tissue RNA - urinary bladder [nTPM]":"47.4","Tissue RNA - vagina [nTPM]":"20.3","Tissue RNA - white matter [nTPM]":"8.5","Cell RNA - A-431 [nTPM]":"25.1","Cell RNA - A549 [nTPM]":"34.2","Cell RNA - AF22 [nTPM]":"5.9","Cell RNA - AN3-CA [nTPM]":"33.2","Cell RNA - ASC diff [nTPM]":"25.0","Cell RNA - ASC TERT1 [nTPM]":"32.0","Cell RNA - BEWO [nTPM]":"10.8","Cell RNA - BJ [nTPM]":"23.6","Cell RNA - BJ hTERT+ [nTPM]":"39.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.9","Cell RNA - CACO-2 [nTPM]":"22.7","Cell RNA - CAPAN-2 [nTPM]":"30.9","Cell RNA - Daudi [nTPM]":"52.8","Cell RNA - EFO-21 [nTPM]":"13.8","Cell RNA - fHDF\/TERT166 [nTPM]":"44.7","Cell RNA - GAMG [nTPM]":"15.8","Cell RNA - HaCaT [nTPM]":"30.9","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"24.2","Cell RNA - HBF TERT88 [nTPM]":"22.1","Cell RNA - HDLM-2 [nTPM]":"39.5","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"28.5","Cell RNA - HeLa [nTPM]":"16.6","Cell RNA - Hep G2 [nTPM]":"36.6","Cell RNA - HHSteC [nTPM]":"21.4","Cell RNA - HL-60 [nTPM]":"36.2","Cell RNA - HMC-1 [nTPM]":"72.0","Cell RNA - HSkMC [nTPM]":"38.4","Cell RNA - hTCEpi [nTPM]":"26.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.2","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"13.2","Cell RNA - HUVEC TERT2 [nTPM]":"39.9","Cell RNA - JURKAT [nTPM]":"40.3","Cell RNA - K-562 [nTPM]":"13.3","Cell RNA - Karpas-707 [nTPM]":"22.3","Cell RNA - LHCN-M2 [nTPM]":"36.8","Cell RNA - MCF7 [nTPM]":"25.7","Cell RNA - MOLT-4 [nTPM]":"61.3","Cell RNA - NB-4 [nTPM]":"12.2","Cell RNA - NTERA-2 [nTPM]":"22.1","Cell RNA - OE19 [nTPM]":"52.8","Cell RNA - PC-3 [nTPM]":"35.7","Cell RNA - REH [nTPM]":"24.8","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"23.1","Cell RNA - RPTEC TERT1 [nTPM]":"37.6","Cell RNA - RT4 [nTPM]":"58.9","Cell RNA - SCLC-21H [nTPM]":"3.0","Cell RNA - SH-SY5Y [nTPM]":"12.0","Cell RNA - SiHa [nTPM]":"33.4","Cell RNA - SK-BR-3 [nTPM]":"172.1","Cell RNA - SK-MEL-30 [nTPM]":"22.3","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"25.8","Cell RNA - THP-1 [nTPM]":"40.8","Cell RNA - TIME [nTPM]":"35.5","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"7.9","Cell RNA - U-2197 [nTPM]":"60.6","Cell RNA - U-251 MG [nTPM]":"24.0","Cell RNA - U-266\/70 [nTPM]":"28.9","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"38.5","Cell RNA - U-87 MG [nTPM]":"25.0","Cell RNA - U-937 [nTPM]":"63.0","Cell RNA - WM-115 [nTPM]":"28.9","Blood RNA - basophil [nTPM]":"288.5","Blood RNA - classical monocyte [nTPM]":"236.9","Blood RNA - eosinophil [nTPM]":"296.9","Blood RNA - gdT-cell [nTPM]":"67.2","Blood RNA - intermediate monocyte [nTPM]":"333.6","Blood RNA - MAIT T-cell [nTPM]":"58.1","Blood RNA - memory B-cell [nTPM]":"43.7","Blood RNA - memory CD4 T-cell [nTPM]":"60.6","Blood RNA - memory CD8 T-cell [nTPM]":"69.3","Blood RNA - myeloid DC [nTPM]":"203.6","Blood RNA - naive B-cell [nTPM]":"35.2","Blood RNA - naive CD4 T-cell [nTPM]":"42.1","Blood RNA - naive CD8 T-cell [nTPM]":"59.5","Blood RNA - neutrophil [nTPM]":"284.7","Blood RNA - NK-cell [nTPM]":"54.6","Blood RNA - non-classical monocyte [nTPM]":"436.1","Blood RNA - plasmacytoid DC [nTPM]":"99.9","Blood RNA - T-reg [nTPM]":"87.4","Blood RNA - total PBMC [nTPM]":"257.3","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"7.7","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"8.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"19.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"16.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - dendritic cells [nTPM]":"35.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"15.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.6","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"10.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"33.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"75.4","Single Cell Type RNA - Langerhans cells [nTPM]":"40.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"61.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"58.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.0","Single Cell Type RNA - Paneth cells [nTPM]":"34.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"19.6","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"49.4"},{"Gene":"MYO5A","Gene synonym":["GS1","MYH12","MYO5","MYR12"],"Ensembl":"ENSG00000197535","Gene description":"Myosin VA","Uniprot":["Q9Y4I1"],"Chromosome":"15","Position":"52307283-52529050","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":["Actin-binding","Calmodulin-binding","Motor protein","Myosin"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"39.1","parathyroid gland":"47.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"353.0","Inhibitory neurons":"241.0","Oligodendrocyte precursor cells":"330.8","Oligodendrocytes":"404.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"25.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"201.0","RPMI-8226":"140.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001356"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Focal adhesion sites","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Focal adhesion sites","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"HPA001356":"AB_1079441"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-4"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"8.3","Tissue RNA - amygdala [nTPM]":"17.0","Tissue RNA - appendix [nTPM]":"12.1","Tissue RNA - basal ganglia [nTPM]":"20.8","Tissue RNA - bone marrow [nTPM]":"21.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"39.1","Tissue RNA - cervix [nTPM]":"6.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"19.0","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"5.3","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"9.6","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"47.4","Tissue RNA - pituitary gland [nTPM]":"8.9","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"5.1","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"26.1","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"5.4","Tissue RNA - skin 1 [nTPM]":"11.8","Tissue RNA - small intestine [nTPM]":"5.0","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"9.5","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"13.1","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"20.8","Cell RNA - A-431 [nTPM]":"19.5","Cell RNA - A549 [nTPM]":"33.7","Cell RNA - AF22 [nTPM]":"17.6","Cell RNA - AN3-CA [nTPM]":"21.3","Cell RNA - ASC diff [nTPM]":"16.2","Cell RNA - ASC TERT1 [nTPM]":"19.3","Cell RNA - BEWO [nTPM]":"19.0","Cell RNA - BJ [nTPM]":"34.7","Cell RNA - BJ hTERT+ [nTPM]":"31.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.0","Cell RNA - CACO-2 [nTPM]":"3.2","Cell RNA - CAPAN-2 [nTPM]":"7.8","Cell RNA - Daudi [nTPM]":"18.7","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"41.8","Cell RNA - GAMG [nTPM]":"26.5","Cell RNA - HaCaT [nTPM]":"15.7","Cell RNA - HAP1 [nTPM]":"40.7","Cell RNA - HBEC3-KT [nTPM]":"35.6","Cell RNA - HBF TERT88 [nTPM]":"22.3","Cell RNA - HDLM-2 [nTPM]":"105.5","Cell RNA - HEK 293 [nTPM]":"9.6","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"8.8","Cell RNA - Hep G2 [nTPM]":"4.2","Cell RNA - HHSteC [nTPM]":"8.3","Cell RNA - HL-60 [nTPM]":"9.0","Cell RNA - HMC-1 [nTPM]":"16.3","Cell RNA - HSkMC [nTPM]":"13.0","Cell RNA - hTCEpi [nTPM]":"21.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.6","Cell RNA - hTERT-HME1 [nTPM]":"52.4","Cell RNA - hTERT-RPE1 [nTPM]":"17.6","Cell RNA - HUVEC TERT2 [nTPM]":"106.8","Cell RNA - JURKAT [nTPM]":"12.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"201.0","Cell RNA - LHCN-M2 [nTPM]":"34.8","Cell RNA - MCF7 [nTPM]":"34.4","Cell RNA - MOLT-4 [nTPM]":"8.2","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"26.6","Cell RNA - REH [nTPM]":"14.5","Cell RNA - RH-30 [nTPM]":"27.8","Cell RNA - RPMI-8226 [nTPM]":"140.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.1","Cell RNA - RT4 [nTPM]":"14.0","Cell RNA - SCLC-21H [nTPM]":"12.7","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"32.3","Cell RNA - SK-BR-3 [nTPM]":"26.2","Cell RNA - SK-MEL-30 [nTPM]":"59.4","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"14.0","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"52.0","Cell RNA - U-138 MG [nTPM]":"36.4","Cell RNA - U-2 OS [nTPM]":"15.7","Cell RNA - U-2197 [nTPM]":"17.1","Cell RNA - U-251 MG [nTPM]":"34.1","Cell RNA - U-266\/70 [nTPM]":"20.9","Cell RNA - U-266\/84 [nTPM]":"49.9","Cell RNA - U-698 [nTPM]":"22.0","Cell RNA - U-87 MG [nTPM]":"39.4","Cell RNA - U-937 [nTPM]":"25.1","Cell RNA - WM-115 [nTPM]":"53.5","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"17.0","Brain RNA - basal ganglia [nTPM]":"20.8","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"39.1","Brain RNA - hippocampal formation [nTPM]":"19.0","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"9.6","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"20.8","Single Cell Type RNA - Adipocytes [nTPM]":"11.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.4","Single Cell Type RNA - Astrocytes [nTPM]":"68.2","Single Cell Type RNA - B-cells [nTPM]":"19.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"75.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"19.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"18.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.0","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"353.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"22.8","Single Cell Type RNA - Granulosa cells [nTPM]":"5.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.4","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"241.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"27.1","Single Cell Type RNA - Langerhans cells [nTPM]":"28.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.8","Single Cell Type RNA - Leydig cells [nTPM]":"3.7","Single Cell Type RNA - Macrophages [nTPM]":"50.2","Single Cell Type RNA - Melanocytes [nTPM]":"97.8","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"36.7","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"330.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"404.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"32.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"14.0","Single Cell Type RNA - Spermatogonia [nTPM]":"9.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"23.7","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"7.3"},{"Gene":"NBN","Gene synonym":["AT-V1","AT-V2","ATV","NBS","NBS1"],"Ensembl":"ENSG00000104320","Gene description":"Nibrin","Uniprot":["O60934"],"Chromosome":"8","Position":"89933331-90003228","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair","Host-virus interaction","Meiosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"265.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001429","CAB003836"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB003836":"AB_562172","HPA001429":"AB_1854460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.5","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"27.8","Tissue RNA - basal ganglia [nTPM]":"12.8","Tissue RNA - bone marrow [nTPM]":"54.0","Tissue RNA - breast [nTPM]":"25.4","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"18.3","Tissue RNA - duodenum [nTPM]":"15.1","Tissue RNA - endometrium 1 [nTPM]":"22.3","Tissue RNA - epididymis [nTPM]":"11.4","Tissue RNA - esophagus [nTPM]":"20.0","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"22.5","Tissue RNA - heart muscle [nTPM]":"12.1","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.5","Tissue RNA - kidney [nTPM]":"20.7","Tissue RNA - liver [nTPM]":"22.3","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"24.3","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"15.5","Tissue RNA - parathyroid gland [nTPM]":"15.4","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"17.5","Tissue RNA - rectum [nTPM]":"22.5","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"16.6","Tissue RNA - seminal vesicle [nTPM]":"14.9","Tissue RNA - skeletal muscle [nTPM]":"10.0","Tissue RNA - skin 1 [nTPM]":"10.3","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"24.2","Tissue RNA - spinal cord [nTPM]":"11.0","Tissue RNA - spleen [nTPM]":"23.4","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"16.4","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"19.0","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"16.2","Tissue RNA - tonsil [nTPM]":"26.4","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"54.8","Cell RNA - A549 [nTPM]":"30.1","Cell RNA - AF22 [nTPM]":"29.3","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"16.5","Cell RNA - ASC TERT1 [nTPM]":"38.7","Cell RNA - BEWO [nTPM]":"18.9","Cell RNA - BJ [nTPM]":"37.9","Cell RNA - BJ hTERT+ [nTPM]":"49.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.8","Cell RNA - CACO-2 [nTPM]":"17.2","Cell RNA - CAPAN-2 [nTPM]":"41.8","Cell RNA - Daudi [nTPM]":"83.8","Cell RNA - EFO-21 [nTPM]":"42.2","Cell RNA - fHDF\/TERT166 [nTPM]":"35.5","Cell RNA - GAMG [nTPM]":"19.1","Cell RNA - HaCaT [nTPM]":"17.7","Cell RNA - HAP1 [nTPM]":"35.7","Cell RNA - HBEC3-KT [nTPM]":"35.7","Cell RNA - HBF TERT88 [nTPM]":"59.8","Cell RNA - HDLM-2 [nTPM]":"38.0","Cell RNA - HEK 293 [nTPM]":"19.7","Cell RNA - HEL [nTPM]":"67.7","Cell RNA - HeLa [nTPM]":"16.8","Cell RNA - Hep G2 [nTPM]":"23.6","Cell RNA - HHSteC [nTPM]":"30.8","Cell RNA - HL-60 [nTPM]":"40.0","Cell RNA - HMC-1 [nTPM]":"35.2","Cell RNA - HSkMC [nTPM]":"30.5","Cell RNA - hTCEpi [nTPM]":"18.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.2","Cell RNA - hTERT-HME1 [nTPM]":"57.9","Cell RNA - hTERT-RPE1 [nTPM]":"22.8","Cell RNA - HUVEC TERT2 [nTPM]":"39.5","Cell RNA - JURKAT [nTPM]":"33.9","Cell RNA - K-562 [nTPM]":"50.6","Cell RNA - Karpas-707 [nTPM]":"46.6","Cell RNA - LHCN-M2 [nTPM]":"55.3","Cell RNA - MCF7 [nTPM]":"46.9","Cell RNA - MOLT-4 [nTPM]":"65.6","Cell RNA - NB-4 [nTPM]":"26.0","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"39.5","Cell RNA - PC-3 [nTPM]":"31.4","Cell RNA - REH [nTPM]":"42.3","Cell RNA - RH-30 [nTPM]":"25.3","Cell RNA - RPMI-8226 [nTPM]":"47.0","Cell RNA - RPTEC TERT1 [nTPM]":"62.8","Cell RNA - RT4 [nTPM]":"73.8","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"26.6","Cell RNA - SiHa [nTPM]":"23.5","Cell RNA - SK-BR-3 [nTPM]":"265.1","Cell RNA - SK-MEL-30 [nTPM]":"23.1","Cell RNA - SuSa [nTPM]":"16.3","Cell RNA - T-47d [nTPM]":"49.8","Cell RNA - THP-1 [nTPM]":"31.4","Cell RNA - TIME [nTPM]":"29.2","Cell RNA - U-138 MG [nTPM]":"40.9","Cell RNA - U-2 OS [nTPM]":"28.0","Cell RNA - U-2197 [nTPM]":"25.5","Cell RNA - U-251 MG [nTPM]":"38.0","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"25.0","Cell RNA - U-698 [nTPM]":"45.5","Cell RNA - U-87 MG [nTPM]":"41.3","Cell RNA - U-937 [nTPM]":"39.4","Cell RNA - WM-115 [nTPM]":"39.1","Blood RNA - basophil [nTPM]":"32.4","Blood RNA - classical monocyte [nTPM]":"17.7","Blood RNA - eosinophil [nTPM]":"32.9","Blood RNA - gdT-cell [nTPM]":"11.9","Blood RNA - intermediate monocyte [nTPM]":"19.7","Blood RNA - MAIT T-cell [nTPM]":"12.7","Blood RNA - memory B-cell [nTPM]":"15.2","Blood RNA - memory CD4 T-cell [nTPM]":"8.5","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"18.9","Blood RNA - naive B-cell [nTPM]":"8.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"9.0","Blood RNA - neutrophil [nTPM]":"34.4","Blood RNA - NK-cell [nTPM]":"16.1","Blood RNA - non-classical monocyte [nTPM]":"31.5","Blood RNA - plasmacytoid DC [nTPM]":"10.4","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"12.8","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.5","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"11.0","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"36.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.2","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"39.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"33.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"29.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"35.1","Single Cell Type RNA - Early spermatids [nTPM]":"17.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.9","Single Cell Type RNA - Endothelial cells [nTPM]":"22.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"31.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.7","Single Cell Type RNA - Fibroblasts [nTPM]":"36.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.2","Single Cell Type RNA - granulocytes [nTPM]":"79.7","Single Cell Type RNA - Granulosa cells [nTPM]":"38.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"30.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.9","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"29.2","Single Cell Type RNA - Langerhans cells [nTPM]":"27.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"51.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"54.7","Single Cell Type RNA - Muller glia cells [nTPM]":"29.4","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.7","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"38.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.7","Single Cell Type RNA - Spermatocytes [nTPM]":"20.2","Single Cell Type RNA - Spermatogonia [nTPM]":"46.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.8","Single Cell Type RNA - T-cells [nTPM]":"35.3","Single Cell Type RNA - Theca cells [nTPM]":"68.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"NCF1","Gene synonym":["NCF1A","NOXO2","p47phox","SH3PXD1A"],"Ensembl":"ENSG00000158517","Gene description":"Neutrophil cytosolic factor 1","Uniprot":["P14598"],"Chromosome":"7","Position":"74773962-74789376","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"86.4","lymphoid tissue":"97.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"293.0","dendritic cells":"157.3","Kupffer cells":"119.9","Macrophages":"153.4","monocytes":"329.9","Plasma cells":"205.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"1165.0","classical monocyte":"673.5","eosinophil":"1467.3","neutrophil":"2128.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"2128.0","monocytes":"673.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"Daudi":"96.2","HMC-1":"130.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004524","HPA047836","HPA052095"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004524":"AB_627987","HPA047836":"AB_2680173","HPA052095":"AB_2681721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"38.7","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"86.4","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"2.9","Tissue RNA - cervix [nTPM]":"1.7","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"7.2","Tissue RNA - duodenum [nTPM]":"7.6","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"3.3","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"5.0","Tissue RNA - lung [nTPM]":"17.7","Tissue RNA - lymph node [nTPM]":"56.8","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"5.0","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"26.6","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"97.5","Tissue RNA - stomach 1 [nTPM]":"6.6","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"37.5","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"96.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"2.9","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"0.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"130.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"16.8","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"3.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"20.6","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"16.5","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"8.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"1165.0","Blood RNA - classical monocyte [nTPM]":"673.5","Blood RNA - eosinophil [nTPM]":"1467.3","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"242.3","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"257.0","Blood RNA - memory CD4 T-cell [nTPM]":"10.0","Blood RNA - memory CD8 T-cell [nTPM]":"6.7","Blood RNA - myeloid DC [nTPM]":"77.7","Blood RNA - naive B-cell [nTPM]":"276.6","Blood RNA - naive CD4 T-cell [nTPM]":"15.4","Blood RNA - naive CD8 T-cell [nTPM]":"9.4","Blood RNA - neutrophil [nTPM]":"2128.0","Blood RNA - NK-cell [nTPM]":"10.7","Blood RNA - non-classical monocyte [nTPM]":"60.2","Blood RNA - plasmacytoid DC [nTPM]":"280.9","Blood RNA - T-reg [nTPM]":"11.1","Blood RNA - total PBMC [nTPM]":"514.1","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"2.9","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"293.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"157.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"8.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.5","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"3.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"119.9","Single Cell Type RNA - Langerhans cells [nTPM]":"23.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"153.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"329.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"205.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"63.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"NCF2","Gene synonym":["NOXA2","p67phox"],"Ensembl":"ENSG00000116701","Gene description":"Neutrophil cytosolic factor 2","Uniprot":["P19878"],"Chromosome":"1","Position":"183555562-183590876","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Chronic granulomatous disease","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"191.9","lung":"74.6","lymphoid tissue":"78.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Ductal cells":"68.6","Hofbauer cells":"212.0","Kupffer cells":"137.9","Langerhans cells":"129.5","Macrophages":"194.4","monocytes":"223.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"1313.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"26.4","HMC-1":"21.4","hTERT-HME1":"51.6","RPMI-8226":"20.0","U-2 OS":"50.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002327","HPA006040","CAB022160"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB022160":null,"HPA002327":"AB_1079550","HPA006040":"AB_1854906"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.91e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.9","Tissue RNA - adrenal gland [nTPM]":"5.8","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"76.9","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"191.9","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"10.4","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"23.8","Tissue RNA - heart muscle [nTPM]":"5.6","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"12.7","Tissue RNA - lung [nTPM]":"74.6","Tissue RNA - lymph node [nTPM]":"17.3","Tissue RNA - medulla oblongata [nTPM]":"6.2","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"2.1","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"39.7","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"2.9","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"6.6","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"15.9","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"20.4","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"78.8","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"12.0","Tissue RNA - thymus [nTPM]":"11.3","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"16.9","Tissue RNA - urinary bladder [nTPM]":"24.2","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"26.4","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"3.2","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"14.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"19.0","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"6.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.0","Cell RNA - HMC-1 [nTPM]":"21.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"4.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"51.6","Cell RNA - hTERT-RPE1 [nTPM]":"2.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"5.6","Cell RNA - LHCN-M2 [nTPM]":"5.8","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.5","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"7.0","Cell RNA - RH-30 [nTPM]":"2.2","Cell RNA - RPMI-8226 [nTPM]":"20.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"1.2","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"50.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"4.9","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"10.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"199.5","Blood RNA - classical monocyte [nTPM]":"489.2","Blood RNA - eosinophil [nTPM]":"1313.6","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"348.8","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"14.1","Blood RNA - memory CD4 T-cell [nTPM]":"4.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"246.0","Blood RNA - naive B-cell [nTPM]":"10.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"799.7","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"326.1","Blood RNA - plasmacytoid DC [nTPM]":"13.5","Blood RNA - T-reg [nTPM]":"11.1","Blood RNA - total PBMC [nTPM]":"298.9","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"6.2","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"12.0","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"8.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"17.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"9.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"68.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"212.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"137.9","Single Cell Type RNA - Langerhans cells [nTPM]":"129.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"194.4","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"223.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.3","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"3.7","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"NFKB1","Gene synonym":["KBF1","NF-kappaB","NF-kB1","NFkappaB","NFKB-p50","p105","p50"],"Ensembl":"ENSG00000109320","Gene description":"Nuclear factor kappa B subunit 1","Uniprot":["P19838"],"Chromosome":"4","Position":"102501331-102617302","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","RAS pathway related proteins","Transcription factors"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"610.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004031","HPA027305"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004031":"AB_330564","HPA027305":"AB_1854429"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.76e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Tissue RNA - adipose tissue [nTPM]":"26.7","Tissue RNA - adrenal gland [nTPM]":"16.2","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"30.3","Tissue RNA - basal ganglia [nTPM]":"7.0","Tissue RNA - bone marrow [nTPM]":"34.6","Tissue RNA - breast [nTPM]":"19.8","Tissue RNA - cerebellum [nTPM]":"6.5","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"22.0","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"20.4","Tissue RNA - duodenum [nTPM]":"15.2","Tissue RNA - endometrium 1 [nTPM]":"18.9","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"23.0","Tissue RNA - fallopian tube [nTPM]":"19.1","Tissue RNA - gallbladder [nTPM]":"20.8","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"4.2","Tissue RNA - hypothalamus [nTPM]":"5.8","Tissue RNA - kidney [nTPM]":"17.4","Tissue RNA - liver [nTPM]":"16.4","Tissue RNA - lung [nTPM]":"25.0","Tissue RNA - lymph node [nTPM]":"33.1","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"6.1","Tissue RNA - ovary [nTPM]":"18.8","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"7.7","Tissue RNA - placenta [nTPM]":"21.2","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"19.6","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"17.8","Tissue RNA - skeletal muscle [nTPM]":"20.9","Tissue RNA - skin 1 [nTPM]":"23.7","Tissue RNA - small intestine [nTPM]":"20.3","Tissue RNA - smooth muscle [nTPM]":"17.0","Tissue RNA - spinal cord [nTPM]":"5.6","Tissue RNA - spleen [nTPM]":"23.0","Tissue RNA - stomach 1 [nTPM]":"17.5","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"37.0","Tissue RNA - thyroid gland [nTPM]":"16.3","Tissue RNA - tongue [nTPM]":"10.7","Tissue RNA - tonsil [nTPM]":"35.1","Tissue RNA - urinary bladder [nTPM]":"48.5","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"36.8","Cell RNA - A549 [nTPM]":"19.2","Cell RNA - AF22 [nTPM]":"11.2","Cell RNA - AN3-CA [nTPM]":"13.6","Cell RNA - ASC diff [nTPM]":"27.0","Cell RNA - ASC TERT1 [nTPM]":"28.5","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"20.0","Cell RNA - BJ hTERT+ [nTPM]":"64.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.1","Cell RNA - CACO-2 [nTPM]":"21.5","Cell RNA - CAPAN-2 [nTPM]":"40.8","Cell RNA - Daudi [nTPM]":"58.0","Cell RNA - EFO-21 [nTPM]":"17.6","Cell RNA - fHDF\/TERT166 [nTPM]":"32.6","Cell RNA - GAMG [nTPM]":"39.4","Cell RNA - HaCaT [nTPM]":"29.5","Cell RNA - HAP1 [nTPM]":"22.0","Cell RNA - HBEC3-KT [nTPM]":"34.5","Cell RNA - HBF TERT88 [nTPM]":"35.2","Cell RNA - HDLM-2 [nTPM]":"53.6","Cell RNA - HEK 293 [nTPM]":"10.8","Cell RNA - HEL [nTPM]":"22.7","Cell RNA - HeLa [nTPM]":"14.5","Cell RNA - Hep G2 [nTPM]":"15.0","Cell RNA - HHSteC [nTPM]":"20.0","Cell RNA - HL-60 [nTPM]":"44.3","Cell RNA - HMC-1 [nTPM]":"44.3","Cell RNA - HSkMC [nTPM]":"19.7","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.0","Cell RNA - hTERT-HME1 [nTPM]":"34.4","Cell RNA - hTERT-RPE1 [nTPM]":"15.0","Cell RNA - HUVEC TERT2 [nTPM]":"34.5","Cell RNA - JURKAT [nTPM]":"18.1","Cell RNA - K-562 [nTPM]":"25.8","Cell RNA - Karpas-707 [nTPM]":"34.1","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"17.7","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"9.1","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"24.3","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"33.4","Cell RNA - RH-30 [nTPM]":"25.9","Cell RNA - RPMI-8226 [nTPM]":"24.0","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"38.8","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"38.3","Cell RNA - SK-BR-3 [nTPM]":"37.2","Cell RNA - SK-MEL-30 [nTPM]":"16.3","Cell RNA - SuSa [nTPM]":"8.3","Cell RNA - T-47d [nTPM]":"8.6","Cell RNA - THP-1 [nTPM]":"24.2","Cell RNA - TIME [nTPM]":"40.5","Cell RNA - U-138 MG [nTPM]":"32.5","Cell RNA - U-2 OS [nTPM]":"16.6","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"26.4","Cell RNA - U-266\/70 [nTPM]":"17.0","Cell RNA - U-266\/84 [nTPM]":"13.3","Cell RNA - U-698 [nTPM]":"52.0","Cell RNA - U-87 MG [nTPM]":"20.8","Cell RNA - U-937 [nTPM]":"19.4","Cell RNA - WM-115 [nTPM]":"44.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"3.1","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"7.0","Brain RNA - cerebellum [nTPM]":"6.5","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"4.2","Brain RNA - hypothalamus [nTPM]":"5.8","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"6.1","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"5.6","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"32.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.4","Single Cell Type RNA - Astrocytes [nTPM]":"42.1","Single Cell Type RNA - B-cells [nTPM]":"90.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"165.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"91.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"40.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.4","Single Cell Type RNA - dendritic cells [nTPM]":"119.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"41.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"28.5","Single Cell Type RNA - Early spermatids [nTPM]":"7.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"82.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"62.0","Single Cell Type RNA - Endothelial cells [nTPM]":"47.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.6","Single Cell Type RNA - Erythroid cells [nTPM]":"13.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"78.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.9","Single Cell Type RNA - Fibroblasts [nTPM]":"63.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"207.0","Single Cell Type RNA - granulocytes [nTPM]":"111.1","Single Cell Type RNA - Granulosa cells [nTPM]":"19.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"77.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.2","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"56.2","Single Cell Type RNA - Langerhans cells [nTPM]":"610.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"178.3","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"59.0","Single Cell Type RNA - monocytes [nTPM]":"207.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.5","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"127.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.3","Single Cell Type RNA - Paneth cells [nTPM]":"27.1","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"56.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"78.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"73.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"150.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.2","Single Cell Type RNA - T-cells [nTPM]":"88.2","Single Cell Type RNA - Theca cells [nTPM]":"16.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.4","Single Cell Type RNA - Urothelial cells [nTPM]":"90.2"},{"Gene":"NFKB2","Gene synonym":["LYT-10","NF-kB2","p105","p49\/p100","p52"],"Ensembl":"ENSG00000077150","Gene description":"Nuclear factor kappa B subunit 2","Uniprot":["Q00653"],"Chromosome":"10","Position":"102394110-102402524","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"122.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"5.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"168.0","Karpas-707":"157.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008422","CAB022098","HPA023900"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB022098":null,"HPA008422":"AB_1854434","HPA023900":"AB_1854435"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-5"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.69e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.5","Tissue RNA - adrenal gland [nTPM]":"21.0","Tissue RNA - amygdala [nTPM]":"7.6","Tissue RNA - appendix [nTPM]":"44.4","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"69.3","Tissue RNA - breast [nTPM]":"19.6","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"9.2","Tissue RNA - cervix [nTPM]":"22.9","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"39.1","Tissue RNA - duodenum [nTPM]":"15.5","Tissue RNA - endometrium 1 [nTPM]":"21.6","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"17.7","Tissue RNA - fallopian tube [nTPM]":"20.4","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"20.6","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"34.6","Tissue RNA - liver [nTPM]":"28.2","Tissue RNA - lung [nTPM]":"41.0","Tissue RNA - lymph node [nTPM]":"40.7","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"21.4","Tissue RNA - pancreas [nTPM]":"24.1","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"10.8","Tissue RNA - placenta [nTPM]":"14.7","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"29.0","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"1.1","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"9.1","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"20.0","Tissue RNA - small intestine [nTPM]":"26.5","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"7.5","Tissue RNA - spleen [nTPM]":"50.6","Tissue RNA - stomach 1 [nTPM]":"22.7","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"16.9","Tissue RNA - thyroid gland [nTPM]":"20.1","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"25.7","Tissue RNA - urinary bladder [nTPM]":"37.0","Tissue RNA - vagina [nTPM]":"19.1","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"67.9","Cell RNA - A549 [nTPM]":"48.6","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"31.7","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"16.6","Cell RNA - BEWO [nTPM]":"19.3","Cell RNA - BJ [nTPM]":"18.5","Cell RNA - BJ hTERT+ [nTPM]":"61.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.9","Cell RNA - CACO-2 [nTPM]":"28.6","Cell RNA - CAPAN-2 [nTPM]":"55.2","Cell RNA - Daudi [nTPM]":"32.9","Cell RNA - EFO-21 [nTPM]":"43.5","Cell RNA - fHDF\/TERT166 [nTPM]":"11.9","Cell RNA - GAMG [nTPM]":"48.8","Cell RNA - HaCaT [nTPM]":"40.9","Cell RNA - HAP1 [nTPM]":"20.5","Cell RNA - HBEC3-KT [nTPM]":"28.2","Cell RNA - HBF TERT88 [nTPM]":"6.8","Cell RNA - HDLM-2 [nTPM]":"168.0","Cell RNA - HEK 293 [nTPM]":"11.2","Cell RNA - HEL [nTPM]":"7.0","Cell RNA - HeLa [nTPM]":"11.7","Cell RNA - Hep G2 [nTPM]":"15.9","Cell RNA - HHSteC [nTPM]":"30.1","Cell RNA - HL-60 [nTPM]":"5.1","Cell RNA - HMC-1 [nTPM]":"45.5","Cell RNA - HSkMC [nTPM]":"22.0","Cell RNA - hTCEpi [nTPM]":"14.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.1","Cell RNA - hTERT-HME1 [nTPM]":"32.3","Cell RNA - hTERT-RPE1 [nTPM]":"26.5","Cell RNA - HUVEC TERT2 [nTPM]":"7.8","Cell RNA - JURKAT [nTPM]":"16.1","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"157.8","Cell RNA - LHCN-M2 [nTPM]":"7.4","Cell RNA - MCF7 [nTPM]":"26.4","Cell RNA - MOLT-4 [nTPM]":"7.1","Cell RNA - NB-4 [nTPM]":"22.7","Cell RNA - NTERA-2 [nTPM]":"10.3","Cell RNA - OE19 [nTPM]":"15.7","Cell RNA - PC-3 [nTPM]":"16.6","Cell RNA - REH [nTPM]":"16.8","Cell RNA - RH-30 [nTPM]":"24.5","Cell RNA - RPMI-8226 [nTPM]":"27.0","Cell RNA - RPTEC TERT1 [nTPM]":"34.3","Cell RNA - RT4 [nTPM]":"22.1","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"8.2","Cell RNA - SiHa [nTPM]":"16.2","Cell RNA - SK-BR-3 [nTPM]":"36.7","Cell RNA - SK-MEL-30 [nTPM]":"26.3","Cell RNA - SuSa [nTPM]":"7.2","Cell RNA - T-47d [nTPM]":"29.3","Cell RNA - THP-1 [nTPM]":"16.4","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"19.0","Cell RNA - U-2 OS [nTPM]":"28.9","Cell RNA - U-2197 [nTPM]":"25.4","Cell RNA - U-251 MG [nTPM]":"47.0","Cell RNA - U-266\/70 [nTPM]":"113.1","Cell RNA - U-266\/84 [nTPM]":"105.0","Cell RNA - U-698 [nTPM]":"32.6","Cell RNA - U-87 MG [nTPM]":"31.1","Cell RNA - U-937 [nTPM]":"14.8","Cell RNA - WM-115 [nTPM]":"10.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"2.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"7.6","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"9.2","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.5","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"20.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"88.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"43.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"41.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"29.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"39.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.4","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.8","Single Cell Type RNA - Fibroblasts [nTPM]":"26.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"52.0","Single Cell Type RNA - granulocytes [nTPM]":"71.8","Single Cell Type RNA - Granulosa cells [nTPM]":"5.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"30.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"19.4","Single Cell Type RNA - Langerhans cells [nTPM]":"122.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"52.5","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"75.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.9","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.9","Single Cell Type RNA - Paneth cells [nTPM]":"37.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"49.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.7","Single Cell Type RNA - Spermatogonia [nTPM]":"11.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"54.6","Single Cell Type RNA - Theca cells [nTPM]":"8.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"45.6"},{"Gene":"NFKBIA","Gene synonym":["IkappaBalpha","IKBA","MAD-3","NFKBI"],"Ensembl":"ENSG00000100906","Gene description":"NFKB inhibitor alpha","Uniprot":["P25963"],"Chromosome":"14","Position":"35401513-35404749","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1114.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"4056.6","Langerhans cells":"4828.7","Suprabasal keratinocytes":"3420.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"391.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003815","HPA029207"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003815":"AB_344886","HPA029207":"AB_10603122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"281.0","Tissue RNA - adrenal gland [nTPM]":"171.3","Tissue RNA - amygdala [nTPM]":"75.6","Tissue RNA - appendix [nTPM]":"150.7","Tissue RNA - basal ganglia [nTPM]":"78.0","Tissue RNA - bone marrow [nTPM]":"1114.7","Tissue RNA - breast [nTPM]":"171.4","Tissue RNA - cerebellum [nTPM]":"75.4","Tissue RNA - cerebral cortex [nTPM]":"92.5","Tissue RNA - cervix [nTPM]":"123.8","Tissue RNA - choroid plexus [nTPM]":"78.3","Tissue RNA - colon [nTPM]":"121.0","Tissue RNA - duodenum [nTPM]":"61.2","Tissue RNA - endometrium 1 [nTPM]":"95.5","Tissue RNA - epididymis [nTPM]":"29.6","Tissue RNA - esophagus [nTPM]":"151.8","Tissue RNA - fallopian tube [nTPM]":"141.2","Tissue RNA - gallbladder [nTPM]":"130.4","Tissue RNA - heart muscle [nTPM]":"145.5","Tissue RNA - hippocampal formation [nTPM]":"71.4","Tissue RNA - hypothalamus [nTPM]":"75.9","Tissue RNA - kidney [nTPM]":"104.5","Tissue RNA - liver [nTPM]":"208.1","Tissue RNA - lung [nTPM]":"366.0","Tissue RNA - lymph node [nTPM]":"122.6","Tissue RNA - medulla oblongata [nTPM]":"90.1","Tissue RNA - midbrain [nTPM]":"76.2","Tissue RNA - ovary [nTPM]":"255.7","Tissue RNA - pancreas [nTPM]":"101.9","Tissue RNA - parathyroid gland [nTPM]":"68.8","Tissue RNA - pituitary gland [nTPM]":"92.4","Tissue RNA - placenta [nTPM]":"92.7","Tissue RNA - pons [nTPM]":"81.6","Tissue RNA - prostate [nTPM]":"112.6","Tissue RNA - rectum [nTPM]":"80.9","Tissue RNA - retina [nTPM]":"18.7","Tissue RNA - salivary gland [nTPM]":"118.3","Tissue RNA - seminal vesicle [nTPM]":"110.0","Tissue RNA - skeletal muscle [nTPM]":"139.7","Tissue RNA - skin 1 [nTPM]":"260.5","Tissue RNA - small intestine [nTPM]":"148.5","Tissue RNA - smooth muscle [nTPM]":"92.7","Tissue RNA - spinal cord [nTPM]":"77.0","Tissue RNA - spleen [nTPM]":"226.2","Tissue RNA - stomach 1 [nTPM]":"130.7","Tissue RNA - testis [nTPM]":"31.7","Tissue RNA - thalamus [nTPM]":"84.9","Tissue RNA - thymus [nTPM]":"123.2","Tissue RNA - thyroid gland [nTPM]":"111.9","Tissue RNA - tongue [nTPM]":"138.3","Tissue RNA - tonsil [nTPM]":"181.4","Tissue RNA - urinary bladder [nTPM]":"366.2","Tissue RNA - vagina [nTPM]":"166.8","Tissue RNA - white matter [nTPM]":"79.8","Cell RNA - A-431 [nTPM]":"62.5","Cell RNA - A549 [nTPM]":"54.1","Cell RNA - AF22 [nTPM]":"20.1","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"114.7","Cell RNA - ASC TERT1 [nTPM]":"75.9","Cell RNA - BEWO [nTPM]":"71.1","Cell RNA - BJ [nTPM]":"25.2","Cell RNA - BJ hTERT+ [nTPM]":"240.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"53.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.3","Cell RNA - CACO-2 [nTPM]":"16.9","Cell RNA - CAPAN-2 [nTPM]":"36.5","Cell RNA - Daudi [nTPM]":"37.5","Cell RNA - EFO-21 [nTPM]":"66.1","Cell RNA - fHDF\/TERT166 [nTPM]":"40.2","Cell RNA - GAMG [nTPM]":"125.2","Cell RNA - HaCaT [nTPM]":"79.5","Cell RNA - HAP1 [nTPM]":"38.3","Cell RNA - HBEC3-KT [nTPM]":"104.9","Cell RNA - HBF TERT88 [nTPM]":"76.1","Cell RNA - HDLM-2 [nTPM]":"229.2","Cell RNA - HEK 293 [nTPM]":"14.9","Cell RNA - HEL [nTPM]":"18.6","Cell RNA - HeLa [nTPM]":"39.9","Cell RNA - Hep G2 [nTPM]":"101.4","Cell RNA - HHSteC [nTPM]":"68.6","Cell RNA - HL-60 [nTPM]":"29.9","Cell RNA - HMC-1 [nTPM]":"15.0","Cell RNA - HSkMC [nTPM]":"83.1","Cell RNA - hTCEpi [nTPM]":"103.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.4","Cell RNA - hTERT-HME1 [nTPM]":"92.2","Cell RNA - hTERT-RPE1 [nTPM]":"35.5","Cell RNA - HUVEC TERT2 [nTPM]":"48.6","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"15.9","Cell RNA - Karpas-707 [nTPM]":"58.4","Cell RNA - LHCN-M2 [nTPM]":"38.6","Cell RNA - MCF7 [nTPM]":"73.0","Cell RNA - MOLT-4 [nTPM]":"39.2","Cell RNA - NB-4 [nTPM]":"71.0","Cell RNA - NTERA-2 [nTPM]":"18.6","Cell RNA - OE19 [nTPM]":"60.0","Cell RNA - PC-3 [nTPM]":"33.1","Cell RNA - REH [nTPM]":"87.8","Cell RNA - RH-30 [nTPM]":"23.1","Cell RNA - RPMI-8226 [nTPM]":"31.6","Cell RNA - RPTEC TERT1 [nTPM]":"92.8","Cell RNA - RT4 [nTPM]":"391.7","Cell RNA - SCLC-21H [nTPM]":"17.9","Cell RNA - SH-SY5Y [nTPM]":"31.2","Cell RNA - SiHa [nTPM]":"67.2","Cell RNA - SK-BR-3 [nTPM]":"115.9","Cell RNA - SK-MEL-30 [nTPM]":"29.7","Cell RNA - SuSa [nTPM]":"41.0","Cell RNA - T-47d [nTPM]":"66.1","Cell RNA - THP-1 [nTPM]":"62.2","Cell RNA - TIME [nTPM]":"91.7","Cell RNA - U-138 MG [nTPM]":"72.8","Cell RNA - U-2 OS [nTPM]":"26.5","Cell RNA - U-2197 [nTPM]":"21.3","Cell RNA - U-251 MG [nTPM]":"41.0","Cell RNA - U-266\/70 [nTPM]":"70.9","Cell RNA - U-266\/84 [nTPM]":"77.7","Cell RNA - U-698 [nTPM]":"64.5","Cell RNA - U-87 MG [nTPM]":"60.8","Cell RNA - U-937 [nTPM]":"22.0","Cell RNA - WM-115 [nTPM]":"15.3","Blood RNA - basophil [nTPM]":"322.0","Blood RNA - classical monocyte [nTPM]":"444.9","Blood RNA - eosinophil [nTPM]":"301.4","Blood RNA - gdT-cell [nTPM]":"175.3","Blood RNA - intermediate monocyte [nTPM]":"267.2","Blood RNA - MAIT T-cell [nTPM]":"264.0","Blood RNA - memory B-cell [nTPM]":"258.4","Blood RNA - memory CD4 T-cell [nTPM]":"207.1","Blood RNA - memory CD8 T-cell [nTPM]":"182.5","Blood RNA - myeloid DC [nTPM]":"428.9","Blood RNA - naive B-cell [nTPM]":"329.7","Blood RNA - naive CD4 T-cell [nTPM]":"178.1","Blood RNA - naive CD8 T-cell [nTPM]":"153.0","Blood RNA - neutrophil [nTPM]":"942.9","Blood RNA - NK-cell [nTPM]":"285.9","Blood RNA - non-classical monocyte [nTPM]":"183.7","Blood RNA - plasmacytoid DC [nTPM]":"233.0","Blood RNA - T-reg [nTPM]":"154.9","Blood RNA - total PBMC [nTPM]":"506.4","Brain RNA - amygdala [nTPM]":"75.6","Brain RNA - basal ganglia [nTPM]":"78.0","Brain RNA - cerebellum [nTPM]":"75.4","Brain RNA - cerebral cortex [nTPM]":"92.5","Brain RNA - hippocampal formation [nTPM]":"71.4","Brain RNA - hypothalamus [nTPM]":"75.9","Brain RNA - medulla oblongata [nTPM]":"90.1","Brain RNA - midbrain [nTPM]":"76.2","Brain RNA - pons [nTPM]":"81.6","Brain RNA - spinal cord [nTPM]":"77.0","Brain RNA - thalamus [nTPM]":"84.9","Brain RNA - white matter [nTPM]":"79.8","Single Cell Type RNA - Adipocytes [nTPM]":"802.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"535.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"914.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"505.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4056.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1862.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2061.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1729.6","Single Cell Type RNA - Bipolar cells [nTPM]":"27.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"430.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"414.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"188.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"367.4","Single Cell Type RNA - Club cells [nTPM]":"719.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"196.4","Single Cell Type RNA - dendritic cells [nTPM]":"762.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"447.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"195.6","Single Cell Type RNA - Ductal cells [nTPM]":"875.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"703.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"935.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1079.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"203.5","Single Cell Type RNA - Erythroid cells [nTPM]":"87.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"394.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"174.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1145.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"333.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1440.1","Single Cell Type RNA - granulocytes [nTPM]":"906.1","Single Cell Type RNA - Granulosa cells [nTPM]":"68.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"313.4","Single Cell Type RNA - Hepatocytes [nTPM]":"147.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"791.2","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"453.0","Single Cell Type RNA - Ionocytes [nTPM]":"634.7","Single Cell Type RNA - Kupffer cells [nTPM]":"491.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4828.7","Single Cell Type RNA - Late spermatids [nTPM]":"14.7","Single Cell Type RNA - Leydig cells [nTPM]":"153.1","Single Cell Type RNA - Macrophages [nTPM]":"1609.0","Single Cell Type RNA - Melanocytes [nTPM]":"1085.1","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"428.1","Single Cell Type RNA - Muller glia cells [nTPM]":"95.2","Single Cell Type RNA - NK-cells [nTPM]":"97.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"383.5","Single Cell Type RNA - Paneth cells [nTPM]":"511.5","Single Cell Type RNA - Peritubular cells [nTPM]":"116.2","Single Cell Type RNA - Plasma cells [nTPM]":"1039.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1412.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1051.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"115.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"298.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.4","Single Cell Type RNA - Sertoli cells [nTPM]":"203.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"956.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"847.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"26.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1544.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3420.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"660.0","Single Cell Type RNA - T-cells [nTPM]":"838.4","Single Cell Type RNA - Theca cells [nTPM]":"91.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"346.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1004.6"},{"Gene":"NHEJ1","Gene synonym":["Cernunnos","FLJ12610","XLF"],"Ensembl":"ENSG00000187736","Gene description":"Non-homologous end joining factor 1","Uniprot":["Q9H9Q4"],"Chromosome":"2","Position":"219069357-219160865","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"7.8","Microglial cells":"11.2","Oligodendrocytes":"8.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012334","HPA043869"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB012334":null,"HPA043869":"AB_2678707"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"4.5","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"3.8","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"9.4","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"14.0","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"8.7","Tissue RNA - epididymis [nTPM]":"4.3","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"8.1","Tissue RNA - lung [nTPM]":"6.9","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"9.1","Tissue RNA - pancreas [nTPM]":"8.4","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"8.4","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"17.1","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"9.0","Tissue RNA - testis [nTPM]":"18.7","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"5.8","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"8.7","Tissue RNA - white matter [nTPM]":"3.5","Cell RNA - A-431 [nTPM]":"5.5","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"13.9","Cell RNA - AN3-CA [nTPM]":"12.6","Cell RNA - ASC diff [nTPM]":"15.6","Cell RNA - ASC TERT1 [nTPM]":"17.9","Cell RNA - BEWO [nTPM]":"8.0","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.4","Cell RNA - CACO-2 [nTPM]":"25.4","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"12.2","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"11.4","Cell RNA - GAMG [nTPM]":"13.4","Cell RNA - HaCaT [nTPM]":"7.2","Cell RNA - HAP1 [nTPM]":"20.5","Cell RNA - HBEC3-KT [nTPM]":"10.9","Cell RNA - HBF TERT88 [nTPM]":"11.8","Cell RNA - HDLM-2 [nTPM]":"13.8","Cell RNA - HEK 293 [nTPM]":"9.0","Cell RNA - HEL [nTPM]":"18.1","Cell RNA - HeLa [nTPM]":"10.0","Cell RNA - Hep G2 [nTPM]":"17.5","Cell RNA - HHSteC [nTPM]":"12.5","Cell RNA - HL-60 [nTPM]":"8.5","Cell RNA - HMC-1 [nTPM]":"13.9","Cell RNA - HSkMC [nTPM]":"15.5","Cell RNA - hTCEpi [nTPM]":"21.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.5","Cell RNA - hTERT-HME1 [nTPM]":"12.5","Cell RNA - hTERT-RPE1 [nTPM]":"8.9","Cell RNA - HUVEC TERT2 [nTPM]":"11.1","Cell RNA - JURKAT [nTPM]":"7.8","Cell RNA - K-562 [nTPM]":"22.3","Cell RNA - Karpas-707 [nTPM]":"11.8","Cell RNA - LHCN-M2 [nTPM]":"10.7","Cell RNA - MCF7 [nTPM]":"4.6","Cell RNA - MOLT-4 [nTPM]":"11.5","Cell RNA - NB-4 [nTPM]":"10.3","Cell RNA - NTERA-2 [nTPM]":"15.9","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"8.0","Cell RNA - REH [nTPM]":"14.6","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"10.5","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"10.2","Cell RNA - SH-SY5Y [nTPM]":"11.4","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"15.6","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"8.0","Cell RNA - TIME [nTPM]":"9.9","Cell RNA - U-138 MG [nTPM]":"10.0","Cell RNA - U-2 OS [nTPM]":"9.3","Cell RNA - U-2197 [nTPM]":"4.4","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"13.2","Cell RNA - U-87 MG [nTPM]":"6.1","Cell RNA - U-937 [nTPM]":"16.2","Cell RNA - WM-115 [nTPM]":"10.3","Blood RNA - basophil [nTPM]":"6.3","Blood RNA - classical monocyte [nTPM]":"11.9","Blood RNA - eosinophil [nTPM]":"6.6","Blood RNA - gdT-cell [nTPM]":"7.0","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"12.2","Blood RNA - memory B-cell [nTPM]":"12.0","Blood RNA - memory CD4 T-cell [nTPM]":"11.4","Blood RNA - memory CD8 T-cell [nTPM]":"9.3","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"14.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.4","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"11.6","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"4.8","Blood RNA - T-reg [nTPM]":"12.8","Blood RNA - total PBMC [nTPM]":"9.1","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"3.8","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"3.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NRAS","Gene synonym":["N-ras"],"Ensembl":"ENSG00000213281","Gene description":"NRAS proto-oncogene, GTPase","Uniprot":["P01111"],"Chromosome":"1","Position":"114704469-114716771","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010157","HPA049830","CAB079912"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010157":"AB_632073","CAB079912":"AB_2784586","HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.0","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"25.7","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"58.5","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"27.8","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"12.4","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"24.9","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"30.4","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"28.3","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"11.4","Tissue RNA - rectum [nTPM]":"26.6","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"21.8","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"39.0","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"93.7","Cell RNA - A549 [nTPM]":"24.9","Cell RNA - AF22 [nTPM]":"65.2","Cell RNA - AN3-CA [nTPM]":"24.9","Cell RNA - ASC diff [nTPM]":"26.4","Cell RNA - ASC TERT1 [nTPM]":"56.3","Cell RNA - BEWO [nTPM]":"46.5","Cell RNA - BJ [nTPM]":"43.5","Cell RNA - BJ hTERT+ [nTPM]":"48.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.0","Cell RNA - CACO-2 [nTPM]":"50.4","Cell RNA - CAPAN-2 [nTPM]":"33.9","Cell RNA - Daudi [nTPM]":"70.4","Cell RNA - EFO-21 [nTPM]":"56.3","Cell RNA - fHDF\/TERT166 [nTPM]":"58.9","Cell RNA - GAMG [nTPM]":"55.4","Cell RNA - HaCaT [nTPM]":"26.0","Cell RNA - HAP1 [nTPM]":"88.2","Cell RNA - HBEC3-KT [nTPM]":"70.6","Cell RNA - HBF TERT88 [nTPM]":"113.4","Cell RNA - HDLM-2 [nTPM]":"96.5","Cell RNA - HEK 293 [nTPM]":"34.2","Cell RNA - HEL [nTPM]":"47.8","Cell RNA - HeLa [nTPM]":"34.5","Cell RNA - Hep G2 [nTPM]":"60.2","Cell RNA - HHSteC [nTPM]":"52.3","Cell RNA - HL-60 [nTPM]":"120.0","Cell RNA - HMC-1 [nTPM]":"71.0","Cell RNA - HSkMC [nTPM]":"51.1","Cell RNA - hTCEpi [nTPM]":"56.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.5","Cell RNA - hTERT-HME1 [nTPM]":"66.2","Cell RNA - hTERT-RPE1 [nTPM]":"25.0","Cell RNA - HUVEC TERT2 [nTPM]":"102.8","Cell RNA - JURKAT [nTPM]":"54.6","Cell RNA - K-562 [nTPM]":"77.3","Cell RNA - Karpas-707 [nTPM]":"78.5","Cell RNA - LHCN-M2 [nTPM]":"71.0","Cell RNA - MCF7 [nTPM]":"248.9","Cell RNA - MOLT-4 [nTPM]":"83.5","Cell RNA - NB-4 [nTPM]":"46.4","Cell RNA - NTERA-2 [nTPM]":"111.0","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"62.9","Cell RNA - RH-30 [nTPM]":"116.0","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"70.6","Cell RNA - RT4 [nTPM]":"49.5","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"59.0","Cell RNA - SiHa [nTPM]":"44.7","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"107.1","Cell RNA - SuSa [nTPM]":"75.4","Cell RNA - T-47d [nTPM]":"31.9","Cell RNA - THP-1 [nTPM]":"96.2","Cell RNA - TIME [nTPM]":"79.2","Cell RNA - U-138 MG [nTPM]":"43.3","Cell RNA - U-2 OS [nTPM]":"82.2","Cell RNA - U-2197 [nTPM]":"81.5","Cell RNA - U-251 MG [nTPM]":"90.3","Cell RNA - U-266\/70 [nTPM]":"137.7","Cell RNA - U-266\/84 [nTPM]":"101.6","Cell RNA - U-698 [nTPM]":"81.6","Cell RNA - U-87 MG [nTPM]":"86.4","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"159.0","Blood RNA - basophil [nTPM]":"38.7","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"12.6","Blood RNA - gdT-cell [nTPM]":"11.7","Blood RNA - intermediate monocyte [nTPM]":"19.2","Blood RNA - MAIT T-cell [nTPM]":"10.5","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"12.9","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"15.5","Blood RNA - non-classical monocyte [nTPM]":"17.6","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"25.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - dendritic cells [nTPM]":"27.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.6","Single Cell Type RNA - Erythroid cells [nTPM]":"31.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.4","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.0","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"22.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"29.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.1","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"44.9","Single Cell Type RNA - Langerhans cells [nTPM]":"30.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"30.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"41.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.4","Single Cell Type RNA - Paneth cells [nTPM]":"32.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"39.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"21.9","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.8","Single Cell Type RNA - Urothelial cells [nTPM]":"40.2"},{"Gene":"ORAI1","Gene synonym":["CRACM1","FLJ14466","TMEM142A"],"Ensembl":"ENSG00000276045","Gene description":"ORAI calcium release-activated calcium modulator 1","Uniprot":["Q96D31"],"Chromosome":"12","Position":"121626550-121642677","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Calcium transport","Immunity","Ion transport","Transport"],"Molecular function":["Calcium channel","Calmodulin-binding","Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"60.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"92.3","NK-cells":"88.6","Theca cells":"86.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"81.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016583"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA016583":"AB_1848720"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.30e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.8","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"9.6","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"5.2","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"7.3","Tissue RNA - choroid plexus [nTPM]":"22.1","Tissue RNA - colon [nTPM]":"10.6","Tissue RNA - duodenum [nTPM]":"20.8","Tissue RNA - endometrium 1 [nTPM]":"7.6","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"11.2","Tissue RNA - liver [nTPM]":"12.3","Tissue RNA - lung [nTPM]":"15.5","Tissue RNA - lymph node [nTPM]":"12.0","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"6.7","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"8.7","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"60.1","Tissue RNA - skin 1 [nTPM]":"46.6","Tissue RNA - small intestine [nTPM]":"13.8","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"23.1","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"10.4","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"2.8","Tissue RNA - urinary bladder [nTPM]":"11.1","Tissue RNA - vagina [nTPM]":"7.8","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"18.3","Cell RNA - A549 [nTPM]":"42.0","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"16.9","Cell RNA - ASC diff [nTPM]":"4.0","Cell RNA - ASC TERT1 [nTPM]":"4.9","Cell RNA - BEWO [nTPM]":"18.4","Cell RNA - BJ [nTPM]":"20.5","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.7","Cell RNA - CACO-2 [nTPM]":"33.1","Cell RNA - CAPAN-2 [nTPM]":"16.2","Cell RNA - Daudi [nTPM]":"13.3","Cell RNA - EFO-21 [nTPM]":"31.4","Cell RNA - fHDF\/TERT166 [nTPM]":"3.1","Cell RNA - GAMG [nTPM]":"11.8","Cell RNA - HaCaT [nTPM]":"30.2","Cell RNA - HAP1 [nTPM]":"3.4","Cell RNA - HBEC3-KT [nTPM]":"13.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"41.9","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"23.9","Cell RNA - HeLa [nTPM]":"6.8","Cell RNA - Hep G2 [nTPM]":"16.6","Cell RNA - HHSteC [nTPM]":"10.1","Cell RNA - HL-60 [nTPM]":"18.5","Cell RNA - HMC-1 [nTPM]":"43.7","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"5.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.4","Cell RNA - hTERT-HME1 [nTPM]":"0.9","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.9","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"16.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"41.4","Cell RNA - MOLT-4 [nTPM]":"46.1","Cell RNA - NB-4 [nTPM]":"81.7","Cell RNA - NTERA-2 [nTPM]":"19.6","Cell RNA - OE19 [nTPM]":"10.3","Cell RNA - PC-3 [nTPM]":"35.7","Cell RNA - REH [nTPM]":"16.8","Cell RNA - RH-30 [nTPM]":"7.9","Cell RNA - RPMI-8226 [nTPM]":"20.5","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"16.4","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"10.7","Cell RNA - SK-BR-3 [nTPM]":"11.7","Cell RNA - SK-MEL-30 [nTPM]":"17.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"29.3","Cell RNA - THP-1 [nTPM]":"11.6","Cell RNA - TIME [nTPM]":"23.5","Cell RNA - U-138 MG [nTPM]":"21.0","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"28.6","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"9.4","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"5.6","Cell RNA - U-87 MG [nTPM]":"15.7","Cell RNA - U-937 [nTPM]":"25.9","Cell RNA - WM-115 [nTPM]":"19.1","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"8.2","Blood RNA - gdT-cell [nTPM]":"18.6","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"13.9","Blood RNA - memory B-cell [nTPM]":"6.3","Blood RNA - memory CD4 T-cell [nTPM]":"15.4","Blood RNA - memory CD8 T-cell [nTPM]":"18.8","Blood RNA - myeloid DC [nTPM]":"7.5","Blood RNA - naive B-cell [nTPM]":"9.0","Blood RNA - naive CD4 T-cell [nTPM]":"14.3","Blood RNA - naive CD8 T-cell [nTPM]":"12.5","Blood RNA - neutrophil [nTPM]":"6.9","Blood RNA - NK-cell [nTPM]":"7.5","Blood RNA - non-classical monocyte [nTPM]":"5.2","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"13.7","Blood RNA - total PBMC [nTPM]":"7.6","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"5.2","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"32.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"41.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"92.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.1","Single Cell Type RNA - Endothelial cells [nTPM]":"40.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"23.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.4","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"43.2","Single Cell Type RNA - Hepatocytes [nTPM]":"17.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"28.2","Single Cell Type RNA - Langerhans cells [nTPM]":"65.0","Single Cell Type RNA - Late spermatids [nTPM]":"11.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.4","Single Cell Type RNA - Macrophages [nTPM]":"42.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"27.2","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"88.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.5","Single Cell Type RNA - Paneth cells [nTPM]":"6.3","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"30.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - T-cells [nTPM]":"70.3","Single Cell Type RNA - Theca cells [nTPM]":"86.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"PGM3","Gene synonym":["AGM1","DKFZP434B187","PAGM"],"Ensembl":"ENSG00000013375","Gene description":"Phosphoglucomutase 3","Uniprot":["O95394"],"Chromosome":"6","Position":"83161150-83193936","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism"],"Molecular function":["Isomerase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004998","HPA029759","HPA029760"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004998":"AB_425591","HPA029759":"AB_10600305","HPA029760":"AB_10601109"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.78e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.67e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.96e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Tissue RNA - adipose tissue [nTPM]":"23.6","Tissue RNA - adrenal gland [nTPM]":"21.0","Tissue RNA - amygdala [nTPM]":"12.0","Tissue RNA - appendix [nTPM]":"18.1","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"9.3","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"15.2","Tissue RNA - cervix [nTPM]":"24.4","Tissue RNA - choroid plexus [nTPM]":"19.6","Tissue RNA - colon [nTPM]":"18.0","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"17.1","Tissue RNA - epididymis [nTPM]":"34.5","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"24.6","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"13.6","Tissue RNA - liver [nTPM]":"38.3","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"11.2","Tissue RNA - medulla oblongata [nTPM]":"10.9","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"22.7","Tissue RNA - pancreas [nTPM]":"46.1","Tissue RNA - parathyroid gland [nTPM]":"13.3","Tissue RNA - pituitary gland [nTPM]":"28.2","Tissue RNA - placenta [nTPM]":"47.5","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"51.0","Tissue RNA - rectum [nTPM]":"23.4","Tissue RNA - retina [nTPM]":"26.8","Tissue RNA - salivary gland [nTPM]":"35.8","Tissue RNA - seminal vesicle [nTPM]":"20.3","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"18.2","Tissue RNA - smooth muscle [nTPM]":"18.5","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"11.5","Tissue RNA - stomach 1 [nTPM]":"24.9","Tissue RNA - testis [nTPM]":"32.3","Tissue RNA - thalamus [nTPM]":"11.1","Tissue RNA - thymus [nTPM]":"8.2","Tissue RNA - thyroid gland [nTPM]":"25.6","Tissue RNA - tongue [nTPM]":"8.6","Tissue RNA - tonsil [nTPM]":"15.2","Tissue RNA - urinary bladder [nTPM]":"19.0","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"15.9","Cell RNA - A-431 [nTPM]":"35.1","Cell RNA - A549 [nTPM]":"23.4","Cell RNA - AF22 [nTPM]":"41.8","Cell RNA - AN3-CA [nTPM]":"51.0","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"72.9","Cell RNA - BEWO [nTPM]":"48.9","Cell RNA - BJ [nTPM]":"118.1","Cell RNA - BJ hTERT+ [nTPM]":"82.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"83.3","Cell RNA - CACO-2 [nTPM]":"60.1","Cell RNA - CAPAN-2 [nTPM]":"16.1","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"24.7","Cell RNA - fHDF\/TERT166 [nTPM]":"112.3","Cell RNA - GAMG [nTPM]":"53.0","Cell RNA - HaCaT [nTPM]":"20.1","Cell RNA - HAP1 [nTPM]":"38.4","Cell RNA - HBEC3-KT [nTPM]":"49.5","Cell RNA - HBF TERT88 [nTPM]":"104.6","Cell RNA - HDLM-2 [nTPM]":"14.6","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"22.7","Cell RNA - HeLa [nTPM]":"41.9","Cell RNA - Hep G2 [nTPM]":"105.0","Cell RNA - HHSteC [nTPM]":"77.6","Cell RNA - HL-60 [nTPM]":"22.6","Cell RNA - HMC-1 [nTPM]":"11.2","Cell RNA - HSkMC [nTPM]":"46.2","Cell RNA - hTCEpi [nTPM]":"40.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"96.6","Cell RNA - hTERT-HME1 [nTPM]":"120.0","Cell RNA - hTERT-RPE1 [nTPM]":"55.5","Cell RNA - HUVEC TERT2 [nTPM]":"64.6","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"74.9","Cell RNA - Karpas-707 [nTPM]":"19.6","Cell RNA - LHCN-M2 [nTPM]":"61.0","Cell RNA - MCF7 [nTPM]":"39.1","Cell RNA - MOLT-4 [nTPM]":"3.7","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"18.8","Cell RNA - OE19 [nTPM]":"31.8","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"16.2","Cell RNA - RH-30 [nTPM]":"92.5","Cell RNA - RPMI-8226 [nTPM]":"11.3","Cell RNA - RPTEC TERT1 [nTPM]":"42.0","Cell RNA - RT4 [nTPM]":"36.0","Cell RNA - SCLC-21H [nTPM]":"16.9","Cell RNA - SH-SY5Y [nTPM]":"26.3","Cell RNA - SiHa [nTPM]":"34.8","Cell RNA - SK-BR-3 [nTPM]":"28.5","Cell RNA - SK-MEL-30 [nTPM]":"20.9","Cell RNA - SuSa [nTPM]":"61.8","Cell RNA - T-47d [nTPM]":"27.0","Cell RNA - THP-1 [nTPM]":"25.5","Cell RNA - TIME [nTPM]":"94.2","Cell RNA - U-138 MG [nTPM]":"38.3","Cell RNA - U-2 OS [nTPM]":"21.2","Cell RNA - U-2197 [nTPM]":"74.9","Cell RNA - U-251 MG [nTPM]":"60.5","Cell RNA - U-266\/70 [nTPM]":"36.5","Cell RNA - U-266\/84 [nTPM]":"16.1","Cell RNA - U-698 [nTPM]":"13.0","Cell RNA - U-87 MG [nTPM]":"29.7","Cell RNA - U-937 [nTPM]":"17.7","Cell RNA - WM-115 [nTPM]":"58.4","Blood RNA - basophil [nTPM]":"10.8","Blood RNA - classical monocyte [nTPM]":"4.1","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"3.9","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.7","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"2.1","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"12.0","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"15.2","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"10.9","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"11.1","Brain RNA - white matter [nTPM]":"15.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.7","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"29.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"16.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"36.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.4","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"31.7","Single Cell Type RNA - Early spermatids [nTPM]":"67.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.1","Single Cell Type RNA - Erythroid cells [nTPM]":"6.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"49.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"71.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.4","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"25.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"32.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"20.9","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"8.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"10.1","Single Cell Type RNA - Muller glia cells [nTPM]":"25.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.9","Single Cell Type RNA - Paneth cells [nTPM]":"19.7","Single Cell Type RNA - Peritubular cells [nTPM]":"18.4","Single Cell Type RNA - Plasma cells [nTPM]":"44.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"56.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.6","Single Cell Type RNA - Spermatocytes [nTPM]":"75.5","Single Cell Type RNA - Spermatogonia [nTPM]":"34.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"64.4","Single Cell Type RNA - T-cells [nTPM]":"10.1","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.6","Single Cell Type RNA - Urothelial cells [nTPM]":"25.6"},{"Gene":"PIK3CD","Gene synonym":["p110D"],"Ensembl":"ENSG00000171608","Gene description":"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta","Uniprot":["O00329"],"Chromosome":"1","Position":"9651731-9729114","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Adaptive immunity","Chemotaxis","Differentiation","Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"60.9","lymphoid tissue":"50.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"44.0","granulocytes":"25.3","Kupffer cells":"35.2","Microglial cells":"29.0","NK-cells":"29.9","T-cells":"37.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"153.3","NB-4":"65.9","REH":"68.9","THP-1":"65.4","U-937":"78.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015420","HPA044953"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"CAB015420":"AB_831654","HPA044953":"AB_2679153"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.2","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"33.4","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"60.9","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"6.2","Tissue RNA - choroid plexus [nTPM]":"6.4","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"4.9","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"7.0","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"7.0","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"6.4","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"46.9","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"3.0","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"4.2","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"50.4","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"24.3","Tissue RNA - thyroid gland [nTPM]":"5.5","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"32.0","Tissue RNA - urinary bladder [nTPM]":"7.4","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"8.5","Cell RNA - A-431 [nTPM]":"8.1","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"1.1","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"12.1","Cell RNA - BJ hTERT+ [nTPM]":"24.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.1","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"3.3","Cell RNA - Daudi [nTPM]":"21.5","Cell RNA - EFO-21 [nTPM]":"4.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"12.4","Cell RNA - HaCaT [nTPM]":"2.4","Cell RNA - HAP1 [nTPM]":"2.0","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"16.2","Cell RNA - HDLM-2 [nTPM]":"153.3","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"1.3","Cell RNA - Hep G2 [nTPM]":"9.0","Cell RNA - HHSteC [nTPM]":"5.1","Cell RNA - HL-60 [nTPM]":"56.0","Cell RNA - HMC-1 [nTPM]":"18.7","Cell RNA - HSkMC [nTPM]":"4.3","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.2","Cell RNA - hTERT-HME1 [nTPM]":"9.8","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"3.8","Cell RNA - JURKAT [nTPM]":"14.9","Cell RNA - K-562 [nTPM]":"8.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"15.0","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"65.9","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"68.9","Cell RNA - RH-30 [nTPM]":"13.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.7","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"4.9","Cell RNA - SK-MEL-30 [nTPM]":"11.9","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"65.4","Cell RNA - TIME [nTPM]":"9.8","Cell RNA - U-138 MG [nTPM]":"7.7","Cell RNA - U-2 OS [nTPM]":"7.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"11.5","Cell RNA - U-266\/70 [nTPM]":"4.9","Cell RNA - U-266\/84 [nTPM]":"4.9","Cell RNA - U-698 [nTPM]":"30.1","Cell RNA - U-87 MG [nTPM]":"16.7","Cell RNA - U-937 [nTPM]":"78.6","Cell RNA - WM-115 [nTPM]":"4.4","Blood RNA - basophil [nTPM]":"18.0","Blood RNA - classical monocyte [nTPM]":"23.5","Blood RNA - eosinophil [nTPM]":"40.2","Blood RNA - gdT-cell [nTPM]":"21.6","Blood RNA - intermediate monocyte [nTPM]":"23.0","Blood RNA - MAIT T-cell [nTPM]":"22.6","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"16.3","Blood RNA - memory CD8 T-cell [nTPM]":"19.9","Blood RNA - myeloid DC [nTPM]":"22.5","Blood RNA - naive B-cell [nTPM]":"13.6","Blood RNA - naive CD4 T-cell [nTPM]":"20.9","Blood RNA - naive CD8 T-cell [nTPM]":"23.1","Blood RNA - neutrophil [nTPM]":"63.2","Blood RNA - NK-cell [nTPM]":"25.9","Blood RNA - non-classical monocyte [nTPM]":"29.2","Blood RNA - plasmacytoid DC [nTPM]":"25.7","Blood RNA - T-reg [nTPM]":"13.3","Blood RNA - total PBMC [nTPM]":"38.3","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"7.0","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"8.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"44.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.9","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"35.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"23.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"19.3","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"37.1","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"PNP","Gene synonym":["NP","PUNP"],"Ensembl":"ENSG00000198805","Gene description":"Purine nucleoside phosphorylase","Uniprot":["P00491"],"Chromosome":"14","Position":"20468954-20477089","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Purine salvage"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"333.9","epididymis":"594.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"360.6","Erythroid cells":"227.3","Syncytiotrophoblasts":"646.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"531.3","U-937":"593.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001625"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"58000000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA001625":"AB_1854577"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.43e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Tissue RNA - adipose tissue [nTPM]":"78.6","Tissue RNA - adrenal gland [nTPM]":"24.8","Tissue RNA - amygdala [nTPM]":"16.1","Tissue RNA - appendix [nTPM]":"46.8","Tissue RNA - basal ganglia [nTPM]":"16.6","Tissue RNA - bone marrow [nTPM]":"333.9","Tissue RNA - breast [nTPM]":"34.6","Tissue RNA - cerebellum [nTPM]":"22.6","Tissue RNA - cerebral cortex [nTPM]":"22.7","Tissue RNA - cervix [nTPM]":"25.3","Tissue RNA - choroid plexus [nTPM]":"18.9","Tissue RNA - colon [nTPM]":"52.2","Tissue RNA - duodenum [nTPM]":"120.3","Tissue RNA - endometrium 1 [nTPM]":"14.2","Tissue RNA - epididymis [nTPM]":"594.8","Tissue RNA - esophagus [nTPM]":"87.4","Tissue RNA - fallopian tube [nTPM]":"18.2","Tissue RNA - gallbladder [nTPM]":"56.8","Tissue RNA - heart muscle [nTPM]":"29.0","Tissue RNA - hippocampal formation [nTPM]":"17.7","Tissue RNA - hypothalamus [nTPM]":"19.6","Tissue RNA - kidney [nTPM]":"206.8","Tissue RNA - liver [nTPM]":"98.0","Tissue RNA - lung [nTPM]":"48.6","Tissue RNA - lymph node [nTPM]":"46.7","Tissue RNA - medulla oblongata [nTPM]":"20.3","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"23.2","Tissue RNA - parathyroid gland [nTPM]":"32.0","Tissue RNA - pituitary gland [nTPM]":"19.8","Tissue RNA - placenta [nTPM]":"132.6","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"61.8","Tissue RNA - retina [nTPM]":"27.1","Tissue RNA - salivary gland [nTPM]":"22.6","Tissue RNA - seminal vesicle [nTPM]":"27.4","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"29.6","Tissue RNA - small intestine [nTPM]":"60.3","Tissue RNA - smooth muscle [nTPM]":"38.7","Tissue RNA - spinal cord [nTPM]":"23.1","Tissue RNA - spleen [nTPM]":"44.5","Tissue RNA - stomach 1 [nTPM]":"50.6","Tissue RNA - testis [nTPM]":"7.4","Tissue RNA - thalamus [nTPM]":"21.1","Tissue RNA - thymus [nTPM]":"33.5","Tissue RNA - thyroid gland [nTPM]":"17.8","Tissue RNA - tongue [nTPM]":"10.0","Tissue RNA - tonsil [nTPM]":"64.4","Tissue RNA - urinary bladder [nTPM]":"100.4","Tissue RNA - vagina [nTPM]":"41.5","Tissue RNA - white matter [nTPM]":"20.1","Cell RNA - A-431 [nTPM]":"86.1","Cell RNA - A549 [nTPM]":"113.4","Cell RNA - AF22 [nTPM]":"24.0","Cell RNA - AN3-CA [nTPM]":"53.9","Cell RNA - ASC diff [nTPM]":"26.0","Cell RNA - ASC TERT1 [nTPM]":"21.0","Cell RNA - BEWO [nTPM]":"71.8","Cell RNA - BJ [nTPM]":"85.2","Cell RNA - BJ hTERT+ [nTPM]":"40.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"67.0","Cell RNA - CACO-2 [nTPM]":"66.1","Cell RNA - CAPAN-2 [nTPM]":"76.5","Cell RNA - Daudi [nTPM]":"227.1","Cell RNA - EFO-21 [nTPM]":"96.8","Cell RNA - fHDF\/TERT166 [nTPM]":"45.5","Cell RNA - GAMG [nTPM]":"81.5","Cell RNA - HaCaT [nTPM]":"89.9","Cell RNA - HAP1 [nTPM]":"125.2","Cell RNA - HBEC3-KT [nTPM]":"159.8","Cell RNA - HBF TERT88 [nTPM]":"89.5","Cell RNA - HDLM-2 [nTPM]":"75.0","Cell RNA - HEK 293 [nTPM]":"109.6","Cell RNA - HEL [nTPM]":"189.1","Cell RNA - HeLa [nTPM]":"89.9","Cell RNA - Hep G2 [nTPM]":"109.3","Cell RNA - HHSteC [nTPM]":"24.2","Cell RNA - HL-60 [nTPM]":"531.3","Cell RNA - HMC-1 [nTPM]":"94.7","Cell RNA - HSkMC [nTPM]":"14.4","Cell RNA - hTCEpi [nTPM]":"57.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"206.0","Cell RNA - hTERT-HME1 [nTPM]":"91.0","Cell RNA - hTERT-RPE1 [nTPM]":"37.8","Cell RNA - HUVEC TERT2 [nTPM]":"295.9","Cell RNA - JURKAT [nTPM]":"141.0","Cell RNA - K-562 [nTPM]":"95.4","Cell RNA - Karpas-707 [nTPM]":"137.4","Cell RNA - LHCN-M2 [nTPM]":"86.7","Cell RNA - MCF7 [nTPM]":"79.1","Cell RNA - MOLT-4 [nTPM]":"157.6","Cell RNA - NB-4 [nTPM]":"311.3","Cell RNA - NTERA-2 [nTPM]":"67.5","Cell RNA - OE19 [nTPM]":"215.7","Cell RNA - PC-3 [nTPM]":"186.1","Cell RNA - REH [nTPM]":"130.2","Cell RNA - RH-30 [nTPM]":"35.9","Cell RNA - RPMI-8226 [nTPM]":"88.3","Cell RNA - RPTEC TERT1 [nTPM]":"243.7","Cell RNA - RT4 [nTPM]":"79.6","Cell RNA - SCLC-21H [nTPM]":"101.9","Cell RNA - SH-SY5Y [nTPM]":"22.6","Cell RNA - SiHa [nTPM]":"163.4","Cell RNA - SK-BR-3 [nTPM]":"205.0","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"32.6","Cell RNA - T-47d [nTPM]":"75.5","Cell RNA - THP-1 [nTPM]":"92.5","Cell RNA - TIME [nTPM]":"240.0","Cell RNA - U-138 MG [nTPM]":"46.1","Cell RNA - U-2 OS [nTPM]":"62.6","Cell RNA - U-2197 [nTPM]":"105.1","Cell RNA - U-251 MG [nTPM]":"148.4","Cell RNA - U-266\/70 [nTPM]":"63.1","Cell RNA - U-266\/84 [nTPM]":"113.3","Cell RNA - U-698 [nTPM]":"258.9","Cell RNA - U-87 MG [nTPM]":"39.3","Cell RNA - U-937 [nTPM]":"593.0","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"12.0","Blood RNA - classical monocyte [nTPM]":"30.6","Blood RNA - eosinophil [nTPM]":"10.3","Blood RNA - gdT-cell [nTPM]":"39.8","Blood RNA - intermediate monocyte [nTPM]":"27.3","Blood RNA - MAIT T-cell [nTPM]":"73.6","Blood RNA - memory B-cell [nTPM]":"25.7","Blood RNA - memory CD4 T-cell [nTPM]":"44.2","Blood RNA - memory CD8 T-cell [nTPM]":"45.0","Blood RNA - myeloid DC [nTPM]":"48.1","Blood RNA - naive B-cell [nTPM]":"28.8","Blood RNA - naive CD4 T-cell [nTPM]":"27.6","Blood RNA - naive CD8 T-cell [nTPM]":"35.9","Blood RNA - neutrophil [nTPM]":"3.7","Blood RNA - NK-cell [nTPM]":"38.5","Blood RNA - non-classical monocyte [nTPM]":"26.6","Blood RNA - plasmacytoid DC [nTPM]":"27.3","Blood RNA - T-reg [nTPM]":"16.7","Blood RNA - total PBMC [nTPM]":"31.1","Brain RNA - amygdala [nTPM]":"16.1","Brain RNA - basal ganglia [nTPM]":"16.6","Brain RNA - cerebellum [nTPM]":"22.6","Brain RNA - cerebral cortex [nTPM]":"22.7","Brain RNA - hippocampal formation [nTPM]":"17.7","Brain RNA - hypothalamus [nTPM]":"19.6","Brain RNA - medulla oblongata [nTPM]":"20.3","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"23.1","Brain RNA - thalamus [nTPM]":"21.1","Brain RNA - white matter [nTPM]":"20.1","Single Cell Type RNA - Adipocytes [nTPM]":"149.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"50.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"84.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"67.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"112.7","Single Cell Type RNA - Bipolar cells [nTPM]":"4.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"56.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"62.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"13.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"82.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"360.6","Single Cell Type RNA - dendritic cells [nTPM]":"45.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"61.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"43.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.7","Single Cell Type RNA - Endothelial cells [nTPM]":"139.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.4","Single Cell Type RNA - Erythroid cells [nTPM]":"227.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"41.8","Single Cell Type RNA - Fibroblasts [nTPM]":"32.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"106.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"65.3","Single Cell Type RNA - granulocytes [nTPM]":"57.7","Single Cell Type RNA - Granulosa cells [nTPM]":"5.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"30.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"70.9","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"51.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"18.1","Single Cell Type RNA - Langerhans cells [nTPM]":"58.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"83.3","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"13.2","Single Cell Type RNA - Muller glia cells [nTPM]":"78.8","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"130.8","Single Cell Type RNA - Paneth cells [nTPM]":"83.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"88.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"118.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"114.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"63.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"646.2","Single Cell Type RNA - T-cells [nTPM]":"62.3","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.4","Single Cell Type RNA - Urothelial cells [nTPM]":"77.1"},{"Gene":"PRF1","Gene synonym":["HPLH2","P1","PFP"],"Ensembl":"ENSG00000180644","Gene description":"Perforin 1","Uniprot":["P14222"],"Chromosome":"10","Position":"70597348-70602759","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cytolysis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Familial hemophagocytic lymphohistiocytosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"28.6","lung":"16.5","lymphoid tissue":"49.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"542.1","NK-cells":"1231.7","T-cells":"265.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"900.4","MAIT T-cell":"628.8","memory CD8 T-cell":"499.1","naive CD8 T-cell":"313.0","NK-cell":"656.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"50","RNA blood lineage specific nTPM":{"NK-cells":"656.8","T-cells":"900.4"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"HDLM-2":"240.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002436","HPA037940"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002436":"AB_563955","HPA037940":"AB_2675747"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.09e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.54e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"7.6","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"28.6","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"2.2","Tissue RNA - duodenum [nTPM]":"2.3","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"1.9","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"1.7","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"16.5","Tissue RNA - lymph node [nTPM]":"20.3","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"1.5","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"49.4","Tissue RNA - stomach 1 [nTPM]":"4.7","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"5.8","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"4.9","Tissue RNA - urinary bladder [nTPM]":"3.8","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"240.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"11.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"900.4","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"628.8","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"125.8","Blood RNA - memory CD8 T-cell [nTPM]":"499.1","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"3.5","Blood RNA - naive CD4 T-cell [nTPM]":"52.1","Blood RNA - naive CD8 T-cell [nTPM]":"313.0","Blood RNA - neutrophil [nTPM]":"15.4","Blood RNA - NK-cell [nTPM]":"656.8","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"108.8","Blood RNA - total PBMC [nTPM]":"587.5","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"542.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"2.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1231.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"88.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"265.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PRKCD","Gene synonym":[],"Ensembl":"ENSG00000163932","Gene description":"Protein kinase C delta","Uniprot":["Q05655"],"Chromosome":"3","Position":"53156009-53192717","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"75.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"57.0","granulocytes":"52.9","monocytes":"73.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"267.7","THP-1":"194.0"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"121.4","thalamus":"334.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001863","HPA001890","CAB010469","CAB013225"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Endoplasmic reticulum","Golgi apparatus"],"Antibody RRID":{"CAB010469":"AB_632229","CAB013225":null,"HPA001863":"AB_1079627","HPA001890":"AB_1079628"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.24e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.01e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Tissue RNA - adipose tissue [nTPM]":"46.1","Tissue RNA - adrenal gland [nTPM]":"59.7","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"45.4","Tissue RNA - basal ganglia [nTPM]":"11.1","Tissue RNA - bone marrow [nTPM]":"90.3","Tissue RNA - breast [nTPM]":"28.9","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"25.9","Tissue RNA - choroid plexus [nTPM]":"7.3","Tissue RNA - colon [nTPM]":"43.5","Tissue RNA - duodenum [nTPM]":"54.8","Tissue RNA - endometrium 1 [nTPM]":"9.1","Tissue RNA - epididymis [nTPM]":"39.1","Tissue RNA - esophagus [nTPM]":"32.7","Tissue RNA - fallopian tube [nTPM]":"42.3","Tissue RNA - gallbladder [nTPM]":"32.8","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"11.0","Tissue RNA - kidney [nTPM]":"25.6","Tissue RNA - liver [nTPM]":"8.8","Tissue RNA - lung [nTPM]":"44.3","Tissue RNA - lymph node [nTPM]":"46.8","Tissue RNA - medulla oblongata [nTPM]":"9.9","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"13.6","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"20.7","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"20.5","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"39.3","Tissue RNA - rectum [nTPM]":"41.5","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"31.9","Tissue RNA - skeletal muscle [nTPM]":"6.8","Tissue RNA - skin 1 [nTPM]":"34.0","Tissue RNA - small intestine [nTPM]":"55.7","Tissue RNA - smooth muscle [nTPM]":"16.2","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"54.2","Tissue RNA - stomach 1 [nTPM]":"65.1","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"41.8","Tissue RNA - tongue [nTPM]":"9.2","Tissue RNA - tonsil [nTPM]":"62.1","Tissue RNA - urinary bladder [nTPM]":"44.2","Tissue RNA - vagina [nTPM]":"23.2","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"33.5","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"5.2","Cell RNA - AN3-CA [nTPM]":"8.7","Cell RNA - ASC diff [nTPM]":"35.9","Cell RNA - ASC TERT1 [nTPM]":"21.6","Cell RNA - BEWO [nTPM]":"46.2","Cell RNA - BJ [nTPM]":"20.4","Cell RNA - BJ hTERT+ [nTPM]":"25.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.7","Cell RNA - CACO-2 [nTPM]":"34.4","Cell RNA - CAPAN-2 [nTPM]":"31.9","Cell RNA - Daudi [nTPM]":"86.5","Cell RNA - EFO-21 [nTPM]":"8.3","Cell RNA - fHDF\/TERT166 [nTPM]":"45.6","Cell RNA - GAMG [nTPM]":"42.9","Cell RNA - HaCaT [nTPM]":"14.5","Cell RNA - HAP1 [nTPM]":"34.1","Cell RNA - HBEC3-KT [nTPM]":"49.8","Cell RNA - HBF TERT88 [nTPM]":"20.6","Cell RNA - HDLM-2 [nTPM]":"75.2","Cell RNA - HEK 293 [nTPM]":"23.6","Cell RNA - HEL [nTPM]":"50.1","Cell RNA - HeLa [nTPM]":"18.3","Cell RNA - Hep G2 [nTPM]":"32.0","Cell RNA - HHSteC [nTPM]":"23.6","Cell RNA - HL-60 [nTPM]":"64.8","Cell RNA - HMC-1 [nTPM]":"103.4","Cell RNA - HSkMC [nTPM]":"17.1","Cell RNA - hTCEpi [nTPM]":"35.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.6","Cell RNA - hTERT-HME1 [nTPM]":"23.2","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"22.4","Cell RNA - JURKAT [nTPM]":"9.3","Cell RNA - K-562 [nTPM]":"9.7","Cell RNA - Karpas-707 [nTPM]":"11.8","Cell RNA - LHCN-M2 [nTPM]":"36.1","Cell RNA - MCF7 [nTPM]":"85.0","Cell RNA - MOLT-4 [nTPM]":"7.0","Cell RNA - NB-4 [nTPM]":"81.0","Cell RNA - NTERA-2 [nTPM]":"13.0","Cell RNA - OE19 [nTPM]":"51.5","Cell RNA - PC-3 [nTPM]":"23.0","Cell RNA - REH [nTPM]":"7.6","Cell RNA - RH-30 [nTPM]":"13.6","Cell RNA - RPMI-8226 [nTPM]":"20.6","Cell RNA - RPTEC TERT1 [nTPM]":"25.5","Cell RNA - RT4 [nTPM]":"72.8","Cell RNA - SCLC-21H [nTPM]":"8.3","Cell RNA - SH-SY5Y [nTPM]":"6.5","Cell RNA - SiHa [nTPM]":"15.4","Cell RNA - SK-BR-3 [nTPM]":"267.7","Cell RNA - SK-MEL-30 [nTPM]":"39.6","Cell RNA - SuSa [nTPM]":"24.0","Cell RNA - T-47d [nTPM]":"22.6","Cell RNA - THP-1 [nTPM]":"194.0","Cell RNA - TIME [nTPM]":"31.5","Cell RNA - U-138 MG [nTPM]":"11.7","Cell RNA - U-2 OS [nTPM]":"14.4","Cell RNA - U-2197 [nTPM]":"15.4","Cell RNA - U-251 MG [nTPM]":"19.2","Cell RNA - U-266\/70 [nTPM]":"18.1","Cell RNA - U-266\/84 [nTPM]":"33.6","Cell RNA - U-698 [nTPM]":"45.9","Cell RNA - U-87 MG [nTPM]":"27.6","Cell RNA - U-937 [nTPM]":"116.4","Cell RNA - WM-115 [nTPM]":"22.6","Blood RNA - basophil [nTPM]":"51.8","Blood RNA - classical monocyte [nTPM]":"73.7","Blood RNA - eosinophil [nTPM]":"50.1","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"71.3","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"6.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"57.0","Blood RNA - naive B-cell [nTPM]":"8.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"52.9","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"47.7","Blood RNA - plasmacytoid DC [nTPM]":"16.3","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"24.1","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"11.1","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"11.0","Brain RNA - medulla oblongata [nTPM]":"9.9","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"25.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"16.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"61.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"34.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"54.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"47.4","Single Cell Type RNA - Langerhans cells [nTPM]":"43.0","Single Cell Type RNA - Late spermatids [nTPM]":"75.6","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"41.5","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"44.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"55.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"25.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"64.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.1","Single Cell Type RNA - Spermatocytes [nTPM]":"23.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"10.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.0","Single Cell Type RNA - Urothelial cells [nTPM]":"34.6"},{"Gene":"PRKDC","Gene synonym":["DNA-PKC","DNA-PKcs","DNAPK","DNAPKc","DNPK1","HYRC","HYRC1","p350","p460","XRCC7"],"Ensembl":"ENSG00000253729","Gene description":"Protein kinase, DNA-activated, catalytic subunit","Uniprot":["P78527"],"Chromosome":"8","Position":"47773111-47960178","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","DNA damage","DNA recombination","DNA repair","Immunity","Innate immunity","Ribosome biogenesis"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005167","HPA035174"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"250000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB005167":"AB_2172845","HPA035174":"AB_2674504"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.3","Tissue RNA - adrenal gland [nTPM]":"16.8","Tissue RNA - amygdala [nTPM]":"8.6","Tissue RNA - appendix [nTPM]":"14.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"19.2","Tissue RNA - breast [nTPM]":"16.1","Tissue RNA - cerebellum [nTPM]":"9.8","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"16.2","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"20.1","Tissue RNA - epididymis [nTPM]":"8.0","Tissue RNA - esophagus [nTPM]":"24.0","Tissue RNA - fallopian tube [nTPM]":"18.3","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"16.7","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"14.8","Tissue RNA - liver [nTPM]":"14.0","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"10.0","Tissue RNA - ovary [nTPM]":"19.8","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"23.8","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"26.4","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"12.1","Tissue RNA - spinal cord [nTPM]":"10.6","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"16.6","Tissue RNA - testis [nTPM]":"18.3","Tissue RNA - thalamus [nTPM]":"9.6","Tissue RNA - thymus [nTPM]":"27.8","Tissue RNA - thyroid gland [nTPM]":"13.4","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"18.7","Tissue RNA - vagina [nTPM]":"17.5","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"123.5","Cell RNA - A549 [nTPM]":"103.4","Cell RNA - AF22 [nTPM]":"98.4","Cell RNA - AN3-CA [nTPM]":"93.9","Cell RNA - ASC diff [nTPM]":"59.9","Cell RNA - ASC TERT1 [nTPM]":"63.0","Cell RNA - BEWO [nTPM]":"41.6","Cell RNA - BJ [nTPM]":"51.2","Cell RNA - BJ hTERT+ [nTPM]":"49.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"70.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"68.9","Cell RNA - CACO-2 [nTPM]":"68.0","Cell RNA - CAPAN-2 [nTPM]":"39.6","Cell RNA - Daudi [nTPM]":"117.1","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"63.3","Cell RNA - GAMG [nTPM]":"52.3","Cell RNA - HaCaT [nTPM]":"68.5","Cell RNA - HAP1 [nTPM]":"131.3","Cell RNA - HBEC3-KT [nTPM]":"70.2","Cell RNA - HBF TERT88 [nTPM]":"109.3","Cell RNA - HDLM-2 [nTPM]":"26.3","Cell RNA - HEK 293 [nTPM]":"81.8","Cell RNA - HEL [nTPM]":"230.2","Cell RNA - HeLa [nTPM]":"92.1","Cell RNA - Hep G2 [nTPM]":"83.7","Cell RNA - HHSteC [nTPM]":"25.8","Cell RNA - HL-60 [nTPM]":"88.6","Cell RNA - HMC-1 [nTPM]":"46.0","Cell RNA - HSkMC [nTPM]":"45.9","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.3","Cell RNA - hTERT-HME1 [nTPM]":"115.3","Cell RNA - hTERT-RPE1 [nTPM]":"27.1","Cell RNA - HUVEC TERT2 [nTPM]":"73.4","Cell RNA - JURKAT [nTPM]":"79.5","Cell RNA - K-562 [nTPM]":"156.6","Cell RNA - Karpas-707 [nTPM]":"48.0","Cell RNA - LHCN-M2 [nTPM]":"78.8","Cell RNA - MCF7 [nTPM]":"57.7","Cell RNA - MOLT-4 [nTPM]":"125.8","Cell RNA - NB-4 [nTPM]":"72.3","Cell RNA - NTERA-2 [nTPM]":"108.6","Cell RNA - OE19 [nTPM]":"85.6","Cell RNA - PC-3 [nTPM]":"31.2","Cell RNA - REH [nTPM]":"60.8","Cell RNA - RH-30 [nTPM]":"77.3","Cell RNA - RPMI-8226 [nTPM]":"41.2","Cell RNA - RPTEC TERT1 [nTPM]":"35.5","Cell RNA - RT4 [nTPM]":"104.4","Cell RNA - SCLC-21H [nTPM]":"49.2","Cell RNA - SH-SY5Y [nTPM]":"62.5","Cell RNA - SiHa [nTPM]":"158.1","Cell RNA - SK-BR-3 [nTPM]":"50.6","Cell RNA - SK-MEL-30 [nTPM]":"51.1","Cell RNA - SuSa [nTPM]":"60.2","Cell RNA - T-47d [nTPM]":"72.6","Cell RNA - THP-1 [nTPM]":"60.1","Cell RNA - TIME [nTPM]":"86.2","Cell RNA - U-138 MG [nTPM]":"91.5","Cell RNA - U-2 OS [nTPM]":"78.0","Cell RNA - U-2197 [nTPM]":"73.0","Cell RNA - U-251 MG [nTPM]":"104.2","Cell RNA - U-266\/70 [nTPM]":"41.3","Cell RNA - U-266\/84 [nTPM]":"56.7","Cell RNA - U-698 [nTPM]":"162.8","Cell RNA - U-87 MG [nTPM]":"51.7","Cell RNA - U-937 [nTPM]":"97.9","Cell RNA - WM-115 [nTPM]":"75.6","Blood RNA - basophil [nTPM]":"11.4","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"4.1","Blood RNA - gdT-cell [nTPM]":"8.7","Blood RNA - intermediate monocyte [nTPM]":"6.8","Blood RNA - MAIT T-cell [nTPM]":"11.0","Blood RNA - memory B-cell [nTPM]":"13.1","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"9.2","Blood RNA - myeloid DC [nTPM]":"6.5","Blood RNA - naive B-cell [nTPM]":"16.7","Blood RNA - naive CD4 T-cell [nTPM]":"11.2","Blood RNA - naive CD8 T-cell [nTPM]":"10.3","Blood RNA - neutrophil [nTPM]":"7.7","Blood RNA - NK-cell [nTPM]":"12.8","Blood RNA - non-classical monocyte [nTPM]":"13.7","Blood RNA - plasmacytoid DC [nTPM]":"15.3","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"8.6","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"9.8","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"10.0","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"10.6","Brain RNA - thalamus [nTPM]":"9.6","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"73.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.1","Single Cell Type RNA - Astrocytes [nTPM]":"56.8","Single Cell Type RNA - B-cells [nTPM]":"67.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"59.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"77.4","Single Cell Type RNA - Bipolar cells [nTPM]":"103.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"63.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"82.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"44.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"125.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"61.1","Single Cell Type RNA - dendritic cells [nTPM]":"81.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"41.9","Single Cell Type RNA - Early spermatids [nTPM]":"29.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"66.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"166.5","Single Cell Type RNA - Endothelial cells [nTPM]":"59.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.8","Single Cell Type RNA - Erythroid cells [nTPM]":"147.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"85.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"60.6","Single Cell Type RNA - Fibroblasts [nTPM]":"73.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"55.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.6","Single Cell Type RNA - granulocytes [nTPM]":"45.6","Single Cell Type RNA - Granulosa cells [nTPM]":"105.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"41.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.9","Single Cell Type RNA - Horizontal cells [nTPM]":"104.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"77.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.2","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"45.5","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"15.5","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"54.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"63.6","Single Cell Type RNA - Muller glia cells [nTPM]":"73.1","Single Cell Type RNA - NK-cells [nTPM]":"57.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"82.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.6","Single Cell Type RNA - Peritubular cells [nTPM]":"69.6","Single Cell Type RNA - Plasma cells [nTPM]":"69.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.6","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"91.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"69.3","Single Cell Type RNA - Spermatocytes [nTPM]":"100.7","Single Cell Type RNA - Spermatogonia [nTPM]":"106.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"85.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.0","Single Cell Type RNA - T-cells [nTPM]":"71.0","Single Cell Type RNA - Theca cells [nTPM]":"143.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"55.2","Single Cell Type RNA - Urothelial cells [nTPM]":"36.4"},{"Gene":"PTPRC","Gene synonym":["CD45","GP180","LCA","T200"],"Ensembl":"ENSG00000081237","Gene description":"Protein tyrosine phosphatase receptor type C","Uniprot":["P08575"],"Chromosome":"1","Position":"198638457-198757476","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Cancer-related genes","Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"208.6","lymphoid tissue":"329.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"525.2","dendritic cells":"1026.4","Macrophages":"534.1","monocytes":"554.9","NK-cells":"769.3","Plasma cells":"474.2","T-cells":"1049.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"209.9","HEL":"118.0","HL-60":"108.1","JURKAT":"266.4","MOLT-4":"161.1","THP-1":"87.0","U-266\/70":"93.7","U-266\/84":"91.2","U-698":"123.4","U-937":"94.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000052","HPA000440","CAB002800","CAB056154","CAB068221"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000052":"AB_2314143","CAB002800":"AB_2237910","CAB056154":"AB_2665572","CAB068221":"AB_2665571","HPA000440":"AB_611377"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.8","Tissue RNA - adrenal gland [nTPM]":"11.6","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"248.5","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"208.6","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"14.9","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"26.4","Tissue RNA - duodenum [nTPM]":"27.4","Tissue RNA - endometrium 1 [nTPM]":"11.3","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"15.1","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"45.7","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"29.6","Tissue RNA - lung [nTPM]":"68.6","Tissue RNA - lymph node [nTPM]":"329.9","Tissue RNA - medulla oblongata [nTPM]":"12.9","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"5.6","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"11.5","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"30.5","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"13.8","Tissue RNA - seminal vesicle [nTPM]":"6.6","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"42.9","Tissue RNA - smooth muscle [nTPM]":"25.3","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"202.5","Tissue RNA - stomach 1 [nTPM]":"37.9","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"6.9","Tissue RNA - thymus [nTPM]":"306.9","Tissue RNA - thyroid gland [nTPM]":"7.0","Tissue RNA - tongue [nTPM]":"7.6","Tissue RNA - tonsil [nTPM]":"251.2","Tissue RNA - urinary bladder [nTPM]":"62.1","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"14.7","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"209.9","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"118.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"108.1","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"266.4","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"3.3","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"161.1","Cell RNA - NB-4 [nTPM]":"65.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"87.0","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"93.7","Cell RNA - U-266\/84 [nTPM]":"91.2","Cell RNA - U-698 [nTPM]":"123.4","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"94.5","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"226.1","Blood RNA - classical monocyte [nTPM]":"480.0","Blood RNA - eosinophil [nTPM]":"521.4","Blood RNA - gdT-cell [nTPM]":"634.4","Blood RNA - intermediate monocyte [nTPM]":"885.8","Blood RNA - MAIT T-cell [nTPM]":"541.8","Blood RNA - memory B-cell [nTPM]":"249.0","Blood RNA - memory CD4 T-cell [nTPM]":"437.0","Blood RNA - memory CD8 T-cell [nTPM]":"618.1","Blood RNA - myeloid DC [nTPM]":"385.8","Blood RNA - naive B-cell [nTPM]":"245.8","Blood RNA - naive CD4 T-cell [nTPM]":"489.8","Blood RNA - naive CD8 T-cell [nTPM]":"494.1","Blood RNA - neutrophil [nTPM]":"844.3","Blood RNA - NK-cell [nTPM]":"506.9","Blood RNA - non-classical monocyte [nTPM]":"1015.8","Blood RNA - plasmacytoid DC [nTPM]":"57.4","Blood RNA - T-reg [nTPM]":"508.6","Blood RNA - total PBMC [nTPM]":"1340.6","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"12.9","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"11.5","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"6.9","Brain RNA - white matter [nTPM]":"14.7","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"62.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"525.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"14.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"1026.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.3","Single Cell Type RNA - Endothelial cells [nTPM]":"15.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"58.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"17.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"246.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"6.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"96.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"334.9","Single Cell Type RNA - Langerhans cells [nTPM]":"214.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"534.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"201.4","Single Cell Type RNA - monocytes [nTPM]":"554.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"769.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"474.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1049.1","Single Cell Type RNA - Theca cells [nTPM]":"5.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"RAB27A","Gene synonym":["GS2","HsT18676","RAB27","RAM"],"Ensembl":"ENSG00000069974","Gene description":"RAB27A, member RAS oncogene family","Uniprot":["P51159"],"Chromosome":"15","Position":"55202966-55319113","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Exocytosis"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"119.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"147.1","Intestinal goblet cells":"252.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"261.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"208.7","K-562":"238.0","Karpas-707":"179.4","SK-MEL-30":"188.3","U-937":"185.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001333","CAB034046"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034046":"AB_2176724","HPA001333":"AB_1079730"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.56e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"17.5","Tissue RNA - adrenal gland [nTPM]":"27.8","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"40.2","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"100.2","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"53.0","Tissue RNA - duodenum [nTPM]":"30.0","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"20.6","Tissue RNA - fallopian tube [nTPM]":"12.3","Tissue RNA - gallbladder [nTPM]":"17.6","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"19.2","Tissue RNA - liver [nTPM]":"43.6","Tissue RNA - lung [nTPM]":"42.4","Tissue RNA - lymph node [nTPM]":"46.0","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"29.2","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"31.4","Tissue RNA - placenta [nTPM]":"17.6","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"61.2","Tissue RNA - rectum [nTPM]":"66.1","Tissue RNA - retina [nTPM]":"4.2","Tissue RNA - salivary gland [nTPM]":"18.3","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"12.8","Tissue RNA - small intestine [nTPM]":"40.9","Tissue RNA - smooth muscle [nTPM]":"25.8","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"30.8","Tissue RNA - stomach 1 [nTPM]":"119.9","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"19.3","Tissue RNA - thyroid gland [nTPM]":"30.5","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"46.2","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"13.9","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"23.0","Cell RNA - A549 [nTPM]":"10.0","Cell RNA - AF22 [nTPM]":"9.7","Cell RNA - AN3-CA [nTPM]":"11.3","Cell RNA - ASC diff [nTPM]":"8.3","Cell RNA - ASC TERT1 [nTPM]":"38.8","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"29.4","Cell RNA - BJ hTERT+ [nTPM]":"32.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.4","Cell RNA - CACO-2 [nTPM]":"7.0","Cell RNA - CAPAN-2 [nTPM]":"15.6","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"22.3","Cell RNA - fHDF\/TERT166 [nTPM]":"16.0","Cell RNA - GAMG [nTPM]":"38.9","Cell RNA - HaCaT [nTPM]":"16.0","Cell RNA - HAP1 [nTPM]":"15.7","Cell RNA - HBEC3-KT [nTPM]":"27.0","Cell RNA - HBF TERT88 [nTPM]":"18.3","Cell RNA - HDLM-2 [nTPM]":"84.9","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"37.6","Cell RNA - Hep G2 [nTPM]":"18.1","Cell RNA - HHSteC [nTPM]":"56.0","Cell RNA - HL-60 [nTPM]":"208.7","Cell RNA - HMC-1 [nTPM]":"26.5","Cell RNA - HSkMC [nTPM]":"34.3","Cell RNA - hTCEpi [nTPM]":"44.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.0","Cell RNA - hTERT-HME1 [nTPM]":"71.6","Cell RNA - hTERT-RPE1 [nTPM]":"80.7","Cell RNA - HUVEC TERT2 [nTPM]":"46.9","Cell RNA - JURKAT [nTPM]":"26.4","Cell RNA - K-562 [nTPM]":"238.0","Cell RNA - Karpas-707 [nTPM]":"179.4","Cell RNA - LHCN-M2 [nTPM]":"20.7","Cell RNA - MCF7 [nTPM]":"27.7","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"57.6","Cell RNA - NTERA-2 [nTPM]":"3.6","Cell RNA - OE19 [nTPM]":"38.9","Cell RNA - PC-3 [nTPM]":"14.7","Cell RNA - REH [nTPM]":"32.4","Cell RNA - RH-30 [nTPM]":"27.3","Cell RNA - RPMI-8226 [nTPM]":"50.3","Cell RNA - RPTEC TERT1 [nTPM]":"28.7","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"14.9","Cell RNA - SH-SY5Y [nTPM]":"7.1","Cell RNA - SiHa [nTPM]":"31.4","Cell RNA - SK-BR-3 [nTPM]":"15.2","Cell RNA - SK-MEL-30 [nTPM]":"188.3","Cell RNA - SuSa [nTPM]":"24.3","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"162.2","Cell RNA - TIME [nTPM]":"25.3","Cell RNA - U-138 MG [nTPM]":"52.5","Cell RNA - U-2 OS [nTPM]":"20.3","Cell RNA - U-2197 [nTPM]":"33.1","Cell RNA - U-251 MG [nTPM]":"33.6","Cell RNA - U-266\/70 [nTPM]":"72.0","Cell RNA - U-266\/84 [nTPM]":"88.2","Cell RNA - U-698 [nTPM]":"6.0","Cell RNA - U-87 MG [nTPM]":"70.2","Cell RNA - U-937 [nTPM]":"185.1","Cell RNA - WM-115 [nTPM]":"19.0","Blood RNA - basophil [nTPM]":"261.3","Blood RNA - classical monocyte [nTPM]":"72.4","Blood RNA - eosinophil [nTPM]":"99.8","Blood RNA - gdT-cell [nTPM]":"59.2","Blood RNA - intermediate monocyte [nTPM]":"30.1","Blood RNA - MAIT T-cell [nTPM]":"58.2","Blood RNA - memory B-cell [nTPM]":"8.0","Blood RNA - memory CD4 T-cell [nTPM]":"28.6","Blood RNA - memory CD8 T-cell [nTPM]":"61.9","Blood RNA - myeloid DC [nTPM]":"39.0","Blood RNA - naive B-cell [nTPM]":"13.4","Blood RNA - naive CD4 T-cell [nTPM]":"13.9","Blood RNA - naive CD8 T-cell [nTPM]":"37.4","Blood RNA - neutrophil [nTPM]":"114.9","Blood RNA - NK-cell [nTPM]":"34.1","Blood RNA - non-classical monocyte [nTPM]":"24.0","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"36.2","Blood RNA - total PBMC [nTPM]":"48.9","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"27.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"147.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"50.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"81.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"24.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.6","Single Cell Type RNA - Endothelial cells [nTPM]":"32.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"74.3","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"87.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"16.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"93.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.7","Single Cell Type RNA - granulocytes [nTPM]":"31.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.7","Single Cell Type RNA - Hepatocytes [nTPM]":"41.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"252.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"15.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"31.1","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"71.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"104.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.9","Single Cell Type RNA - Paneth cells [nTPM]":"15.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"38.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.8","Single Cell Type RNA - Spermatocytes [nTPM]":"9.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - T-cells [nTPM]":"81.4","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.4","Single Cell Type RNA - Urothelial cells [nTPM]":"23.4"},{"Gene":"RAC2","Gene synonym":["EN-7"],"Ensembl":"ENSG00000128340","Gene description":"Rac family small GTPase 2","Uniprot":["P15153"],"Chromosome":"22","Position":"37225270-37244448","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"411.9","lymphoid tissue":"387.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"329.0","dendritic cells":"381.4","granulocytes":"520.5","NK-cells":"717.9","Plasma cells":"287.8","T-cells":"419.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"522.5","HL-60":"734.5","HMC-1":"1427.9","Karpas-707":"684.5","U-87 MG":"618.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022946","HPA047820"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022946":null,"HPA047820":"AB_2680167"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.03e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.7","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"207.2","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"411.9","Tissue RNA - breast [nTPM]":"11.4","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"12.2","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"34.8","Tissue RNA - duodenum [nTPM]":"35.3","Tissue RNA - endometrium 1 [nTPM]":"10.1","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"15.9","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"37.1","Tissue RNA - heart muscle [nTPM]":"6.5","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"19.3","Tissue RNA - lung [nTPM]":"63.4","Tissue RNA - lymph node [nTPM]":"387.9","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"5.3","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"5.3","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"7.1","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"33.9","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"21.5","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"4.9","Tissue RNA - skin 1 [nTPM]":"7.6","Tissue RNA - small intestine [nTPM]":"96.9","Tissue RNA - smooth muscle [nTPM]":"19.6","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"299.9","Tissue RNA - stomach 1 [nTPM]":"42.7","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"6.1","Tissue RNA - thymus [nTPM]":"323.9","Tissue RNA - thyroid gland [nTPM]":"9.5","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"309.1","Tissue RNA - urinary bladder [nTPM]":"54.0","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"136.6","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"130.5","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"41.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.8","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"44.8","Cell RNA - Daudi [nTPM]":"167.4","Cell RNA - EFO-21 [nTPM]":"19.8","Cell RNA - fHDF\/TERT166 [nTPM]":"52.9","Cell RNA - GAMG [nTPM]":"0.8","Cell RNA - HaCaT [nTPM]":"33.3","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"231.6","Cell RNA - HBF TERT88 [nTPM]":"15.6","Cell RNA - HDLM-2 [nTPM]":"522.5","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"209.6","Cell RNA - HeLa [nTPM]":"3.6","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"35.8","Cell RNA - HL-60 [nTPM]":"734.5","Cell RNA - HMC-1 [nTPM]":"1427.9","Cell RNA - HSkMC [nTPM]":"96.4","Cell RNA - hTCEpi [nTPM]":"32.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.1","Cell RNA - hTERT-HME1 [nTPM]":"84.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"239.7","Cell RNA - JURKAT [nTPM]":"159.1","Cell RNA - K-562 [nTPM]":"50.5","Cell RNA - Karpas-707 [nTPM]":"684.5","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"218.9","Cell RNA - NB-4 [nTPM]":"291.2","Cell RNA - NTERA-2 [nTPM]":"2.8","Cell RNA - OE19 [nTPM]":"13.1","Cell RNA - PC-3 [nTPM]":"87.2","Cell RNA - REH [nTPM]":"72.3","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"193.8","Cell RNA - RPTEC TERT1 [nTPM]":"22.6","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"23.0","Cell RNA - SK-MEL-30 [nTPM]":"2.7","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"9.7","Cell RNA - THP-1 [nTPM]":"391.8","Cell RNA - TIME [nTPM]":"258.7","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"23.5","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"2.0","Cell RNA - U-266\/70 [nTPM]":"307.0","Cell RNA - U-266\/84 [nTPM]":"171.4","Cell RNA - U-698 [nTPM]":"176.6","Cell RNA - U-87 MG [nTPM]":"618.6","Cell RNA - U-937 [nTPM]":"316.5","Cell RNA - WM-115 [nTPM]":"35.1","Blood RNA - basophil [nTPM]":"1319.9","Blood RNA - classical monocyte [nTPM]":"519.8","Blood RNA - eosinophil [nTPM]":"1602.2","Blood RNA - gdT-cell [nTPM]":"972.1","Blood RNA - intermediate monocyte [nTPM]":"695.5","Blood RNA - MAIT T-cell [nTPM]":"731.5","Blood RNA - memory B-cell [nTPM]":"761.7","Blood RNA - memory CD4 T-cell [nTPM]":"768.6","Blood RNA - memory CD8 T-cell [nTPM]":"858.9","Blood RNA - myeloid DC [nTPM]":"494.0","Blood RNA - naive B-cell [nTPM]":"672.8","Blood RNA - naive CD4 T-cell [nTPM]":"584.3","Blood RNA - naive CD8 T-cell [nTPM]":"759.8","Blood RNA - neutrophil [nTPM]":"1336.4","Blood RNA - NK-cell [nTPM]":"972.2","Blood RNA - non-classical monocyte [nTPM]":"879.5","Blood RNA - plasmacytoid DC [nTPM]":"728.7","Blood RNA - T-reg [nTPM]":"1163.4","Blood RNA - total PBMC [nTPM]":"1566.2","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"5.3","Brain RNA - pons [nTPM]":"7.1","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"6.1","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"329.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"381.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"13.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"109.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"9.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"520.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"150.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"129.9","Single Cell Type RNA - Langerhans cells [nTPM]":"63.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"147.9","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"125.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"717.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.2","Single Cell Type RNA - Paneth cells [nTPM]":"18.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"287.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"419.6","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"RAD50","Gene synonym":["hRad50","RAD50-2"],"Ensembl":"ENSG00000113522","Gene description":"RAD50 double strand break repair protein","Uniprot":["Q92878"],"Chromosome":"5","Position":"132556019-132646349","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair","Host-virus interaction","Meiosis"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022103","CAB024979","HPA052291"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB022103":null,"CAB024979":null,"HPA052291":"AB_2681786"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.3","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"6.6","Tissue RNA - cerebellum [nTPM]":"7.6","Tissue RNA - cerebral cortex [nTPM]":"8.6","Tissue RNA - cervix [nTPM]":"6.9","Tissue RNA - choroid plexus [nTPM]":"4.0","Tissue RNA - colon [nTPM]":"8.7","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"7.6","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"3.5","Tissue RNA - heart muscle [nTPM]":"7.1","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"5.0","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"9.2","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"8.8","Tissue RNA - pituitary gland [nTPM]":"8.1","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"5.7","Tissue RNA - prostate [nTPM]":"6.2","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"11.3","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"8.0","Tissue RNA - smooth muscle [nTPM]":"3.8","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"5.4","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"4.7","Tissue RNA - tonsil [nTPM]":"3.5","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"9.1","Cell RNA - A549 [nTPM]":"22.8","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"12.1","Cell RNA - ASC diff [nTPM]":"13.3","Cell RNA - ASC TERT1 [nTPM]":"20.0","Cell RNA - BEWO [nTPM]":"9.8","Cell RNA - BJ [nTPM]":"6.3","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.8","Cell RNA - CACO-2 [nTPM]":"20.4","Cell RNA - CAPAN-2 [nTPM]":"14.8","Cell RNA - Daudi [nTPM]":"20.6","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"10.3","Cell RNA - GAMG [nTPM]":"19.7","Cell RNA - HaCaT [nTPM]":"8.8","Cell RNA - HAP1 [nTPM]":"17.6","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"16.5","Cell RNA - HDLM-2 [nTPM]":"11.7","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"9.5","Cell RNA - HeLa [nTPM]":"13.3","Cell RNA - Hep G2 [nTPM]":"12.5","Cell RNA - HHSteC [nTPM]":"10.8","Cell RNA - HL-60 [nTPM]":"10.2","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"10.8","Cell RNA - hTCEpi [nTPM]":"24.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.4","Cell RNA - hTERT-HME1 [nTPM]":"36.7","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"5.4","Cell RNA - JURKAT [nTPM]":"6.5","Cell RNA - K-562 [nTPM]":"17.9","Cell RNA - Karpas-707 [nTPM]":"3.2","Cell RNA - LHCN-M2 [nTPM]":"10.1","Cell RNA - MCF7 [nTPM]":"8.6","Cell RNA - MOLT-4 [nTPM]":"7.7","Cell RNA - NB-4 [nTPM]":"13.9","Cell RNA - NTERA-2 [nTPM]":"11.7","Cell RNA - OE19 [nTPM]":"9.0","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"10.1","Cell RNA - RPTEC TERT1 [nTPM]":"8.8","Cell RNA - RT4 [nTPM]":"16.9","Cell RNA - SCLC-21H [nTPM]":"11.5","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"11.7","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"2.8","Cell RNA - SuSa [nTPM]":"5.6","Cell RNA - T-47d [nTPM]":"11.5","Cell RNA - THP-1 [nTPM]":"7.0","Cell RNA - TIME [nTPM]":"9.5","Cell RNA - U-138 MG [nTPM]":"4.7","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"8.3","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"7.7","Cell RNA - U-698 [nTPM]":"24.2","Cell RNA - U-87 MG [nTPM]":"8.4","Cell RNA - U-937 [nTPM]":"12.5","Cell RNA - WM-115 [nTPM]":"6.7","Blood RNA - basophil [nTPM]":"7.0","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"3.8","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"5.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.4","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"9.3","Blood RNA - non-classical monocyte [nTPM]":"4.8","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"4.0","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"7.6","Brain RNA - cerebral cortex [nTPM]":"8.6","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"5.7","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.1","Single Cell Type RNA - Astrocytes [nTPM]":"65.6","Single Cell Type RNA - B-cells [nTPM]":"34.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"37.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"56.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"130.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"31.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"69.6","Single Cell Type RNA - dendritic cells [nTPM]":"22.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"26.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.8","Single Cell Type RNA - Endothelial cells [nTPM]":"16.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.1","Single Cell Type RNA - Erythroid cells [nTPM]":"38.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"65.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"49.2","Single Cell Type RNA - Fibroblasts [nTPM]":"37.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"8.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"38.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.4","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"79.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.2","Single Cell Type RNA - Langerhans cells [nTPM]":"12.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.6","Single Cell Type RNA - Leydig cells [nTPM]":"60.6","Single Cell Type RNA - Macrophages [nTPM]":"16.5","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"22.4","Single Cell Type RNA - Muller glia cells [nTPM]":"38.0","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"65.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"92.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"35.6","Single Cell Type RNA - Peritubular cells [nTPM]":"53.4","Single Cell Type RNA - Plasma cells [nTPM]":"33.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"53.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.9","Single Cell Type RNA - Spermatocytes [nTPM]":"108.4","Single Cell Type RNA - Spermatogonia [nTPM]":"87.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.1","Single Cell Type RNA - T-cells [nTPM]":"25.2","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.3","Single Cell Type RNA - Urothelial cells [nTPM]":"25.1"},{"Gene":"RAG1","Gene synonym":["MGC43321","RNF74"],"Ensembl":"ENSG00000166349","Gene description":"Recombination activating 1","Uniprot":["P15918"],"Chromosome":"11","Position":"36510709-36593156","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA recombination","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","DNA-binding","Endonuclease","Hydrolase","Multifunctional enzyme","Nuclease","Transferase"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"92","RNA tissue specific nTPM":{"lymphoid tissue":"395.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"3.9","Hepatic stellate cells":"8.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"MOLT-4":"283.5","REH":"266.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043939"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043939":"AB_2732512"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"395.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"54.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"283.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"266.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"1.2","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"2.3","Cell RNA - U-266\/84 [nTPM]":"1.9","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"RAG2","Gene synonym":[],"Ensembl":"ENSG00000175097","Gene description":"Recombination activating 2","Uniprot":["P55895"],"Chromosome":"11","Position":"36575574-36598279","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA recombination"],"Molecular function":["Chromatin regulator"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"152.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"19","RNA single cell type specific nTPM":{"Astrocytes":"1.3","Early spermatids":"2.3","Excitatory neurons":"2.9","Inhibitory neurons":"1.5","Oligodendrocyte precursor cells":"2.5","Oligodendrocytes":"1.3","Spermatocytes":"1.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"21","RNA cancer specific FPKM":{"thyroid cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"JURKAT":"40.0","MOLT-4":"46.8","REH":"183.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065704"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA065704":"AB_2732737"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"152.3","Tissue RNA - thyroid gland [nTPM]":"23.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"40.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"46.8","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"183.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RFX5","Gene synonym":[],"Ensembl":"ENSG00000143390","Gene description":"Regulatory factor X5","Uniprot":["P48382"],"Chromosome":"1","Position":"151340640-151347326","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"40.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018519","HPA079241"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA018519":"AB_1856209","HPA079241":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.4","Tissue RNA - adrenal gland [nTPM]":"25.6","Tissue RNA - amygdala [nTPM]":"13.3","Tissue RNA - appendix [nTPM]":"43.3","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"24.0","Tissue RNA - breast [nTPM]":"14.9","Tissue RNA - cerebellum [nTPM]":"17.8","Tissue RNA - cerebral cortex [nTPM]":"13.2","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"11.7","Tissue RNA - colon [nTPM]":"22.7","Tissue RNA - duodenum [nTPM]":"31.6","Tissue RNA - endometrium 1 [nTPM]":"22.0","Tissue RNA - epididymis [nTPM]":"13.1","Tissue RNA - esophagus [nTPM]":"18.3","Tissue RNA - fallopian tube [nTPM]":"18.4","Tissue RNA - gallbladder [nTPM]":"23.4","Tissue RNA - heart muscle [nTPM]":"18.3","Tissue RNA - hippocampal formation [nTPM]":"12.3","Tissue RNA - hypothalamus [nTPM]":"16.8","Tissue RNA - kidney [nTPM]":"18.3","Tissue RNA - liver [nTPM]":"13.1","Tissue RNA - lung [nTPM]":"27.9","Tissue RNA - lymph node [nTPM]":"67.7","Tissue RNA - medulla oblongata [nTPM]":"17.1","Tissue RNA - midbrain [nTPM]":"17.6","Tissue RNA - ovary [nTPM]":"10.1","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"22.1","Tissue RNA - pituitary gland [nTPM]":"18.1","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"20.4","Tissue RNA - rectum [nTPM]":"28.1","Tissue RNA - retina [nTPM]":"14.6","Tissue RNA - salivary gland [nTPM]":"16.0","Tissue RNA - seminal vesicle [nTPM]":"25.1","Tissue RNA - skeletal muscle [nTPM]":"17.0","Tissue RNA - skin 1 [nTPM]":"13.1","Tissue RNA - small intestine [nTPM]":"26.1","Tissue RNA - smooth muscle [nTPM]":"31.8","Tissue RNA - spinal cord [nTPM]":"15.4","Tissue RNA - spleen [nTPM]":"50.7","Tissue RNA - stomach 1 [nTPM]":"19.6","Tissue RNA - testis [nTPM]":"15.5","Tissue RNA - thalamus [nTPM]":"15.7","Tissue RNA - thymus [nTPM]":"50.5","Tissue RNA - thyroid gland [nTPM]":"23.7","Tissue RNA - tongue [nTPM]":"23.8","Tissue RNA - tonsil [nTPM]":"71.8","Tissue RNA - urinary bladder [nTPM]":"26.5","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"37.7","Cell RNA - A549 [nTPM]":"41.8","Cell RNA - AF22 [nTPM]":"57.6","Cell RNA - AN3-CA [nTPM]":"32.8","Cell RNA - ASC diff [nTPM]":"27.6","Cell RNA - ASC TERT1 [nTPM]":"24.0","Cell RNA - BEWO [nTPM]":"12.6","Cell RNA - BJ [nTPM]":"17.8","Cell RNA - BJ hTERT+ [nTPM]":"30.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.7","Cell RNA - CACO-2 [nTPM]":"13.7","Cell RNA - CAPAN-2 [nTPM]":"50.9","Cell RNA - Daudi [nTPM]":"145.2","Cell RNA - EFO-21 [nTPM]":"63.9","Cell RNA - fHDF\/TERT166 [nTPM]":"21.5","Cell RNA - GAMG [nTPM]":"42.6","Cell RNA - HaCaT [nTPM]":"59.5","Cell RNA - HAP1 [nTPM]":"24.9","Cell RNA - HBEC3-KT [nTPM]":"34.4","Cell RNA - HBF TERT88 [nTPM]":"31.9","Cell RNA - HDLM-2 [nTPM]":"177.4","Cell RNA - HEK 293 [nTPM]":"39.7","Cell RNA - HEL [nTPM]":"54.8","Cell RNA - HeLa [nTPM]":"89.4","Cell RNA - Hep G2 [nTPM]":"23.0","Cell RNA - HHSteC [nTPM]":"17.7","Cell RNA - HL-60 [nTPM]":"48.9","Cell RNA - HMC-1 [nTPM]":"59.4","Cell RNA - HSkMC [nTPM]":"25.2","Cell RNA - hTCEpi [nTPM]":"18.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.8","Cell RNA - hTERT-HME1 [nTPM]":"13.2","Cell RNA - hTERT-RPE1 [nTPM]":"35.7","Cell RNA - HUVEC TERT2 [nTPM]":"39.9","Cell RNA - JURKAT [nTPM]":"92.0","Cell RNA - K-562 [nTPM]":"26.8","Cell RNA - Karpas-707 [nTPM]":"88.3","Cell RNA - LHCN-M2 [nTPM]":"33.8","Cell RNA - MCF7 [nTPM]":"34.2","Cell RNA - MOLT-4 [nTPM]":"78.7","Cell RNA - NB-4 [nTPM]":"36.2","Cell RNA - NTERA-2 [nTPM]":"41.9","Cell RNA - OE19 [nTPM]":"30.5","Cell RNA - PC-3 [nTPM]":"21.2","Cell RNA - REH [nTPM]":"97.1","Cell RNA - RH-30 [nTPM]":"32.3","Cell RNA - RPMI-8226 [nTPM]":"80.1","Cell RNA - RPTEC TERT1 [nTPM]":"42.0","Cell RNA - RT4 [nTPM]":"49.1","Cell RNA - SCLC-21H [nTPM]":"20.4","Cell RNA - SH-SY5Y [nTPM]":"60.0","Cell RNA - SiHa [nTPM]":"35.7","Cell RNA - SK-BR-3 [nTPM]":"55.0","Cell RNA - SK-MEL-30 [nTPM]":"52.8","Cell RNA - SuSa [nTPM]":"69.2","Cell RNA - T-47d [nTPM]":"51.6","Cell RNA - THP-1 [nTPM]":"114.3","Cell RNA - TIME [nTPM]":"39.9","Cell RNA - U-138 MG [nTPM]":"23.8","Cell RNA - U-2 OS [nTPM]":"25.1","Cell RNA - U-2197 [nTPM]":"11.8","Cell RNA - U-251 MG [nTPM]":"33.7","Cell RNA - U-266\/70 [nTPM]":"110.9","Cell RNA - U-266\/84 [nTPM]":"118.2","Cell RNA - U-698 [nTPM]":"168.6","Cell RNA - U-87 MG [nTPM]":"37.8","Cell RNA - U-937 [nTPM]":"26.4","Cell RNA - WM-115 [nTPM]":"31.3","Blood RNA - basophil [nTPM]":"5.6","Blood RNA - classical monocyte [nTPM]":"22.6","Blood RNA - eosinophil [nTPM]":"11.5","Blood RNA - gdT-cell [nTPM]":"17.4","Blood RNA - intermediate monocyte [nTPM]":"28.2","Blood RNA - MAIT T-cell [nTPM]":"15.3","Blood RNA - memory B-cell [nTPM]":"47.9","Blood RNA - memory CD4 T-cell [nTPM]":"13.9","Blood RNA - memory CD8 T-cell [nTPM]":"17.4","Blood RNA - myeloid DC [nTPM]":"47.4","Blood RNA - naive B-cell [nTPM]":"53.3","Blood RNA - naive CD4 T-cell [nTPM]":"10.9","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"3.1","Blood RNA - NK-cell [nTPM]":"31.4","Blood RNA - non-classical monocyte [nTPM]":"30.8","Blood RNA - plasmacytoid DC [nTPM]":"25.1","Blood RNA - T-reg [nTPM]":"28.5","Blood RNA - total PBMC [nTPM]":"21.5","Brain RNA - amygdala [nTPM]":"13.3","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"17.8","Brain RNA - cerebral cortex [nTPM]":"13.2","Brain RNA - hippocampal formation [nTPM]":"12.3","Brain RNA - hypothalamus [nTPM]":"16.8","Brain RNA - medulla oblongata [nTPM]":"17.1","Brain RNA - midbrain [nTPM]":"17.6","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"15.4","Brain RNA - thalamus [nTPM]":"15.7","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"32.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"12.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"16.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"8.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"9.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"16.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"6.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.1","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"15.7","Single Cell Type RNA - Late spermatids [nTPM]":"17.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"13.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"40.8","Single Cell Type RNA - Muller glia cells [nTPM]":"7.2","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.7","Single Cell Type RNA - Spermatocytes [nTPM]":"15.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"13.7","Single Cell Type RNA - Theca cells [nTPM]":"15.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.6"},{"Gene":"RFXANK","Gene synonym":["ANKRA1","BLS","F14150_1","MGC138628","RFX-B"],"Ensembl":"ENSG00000064490","Gene description":"Regulatory factor X associated ankyrin containing protein","Uniprot":["O14593"],"Chromosome":"19","Position":"19192229-19201869","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049157","HPA053330"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049157":"AB_2680658","HPA053330":"AB_2682114"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-3"},"Tissue RNA - adipose tissue [nTPM]":"30.2","Tissue RNA - adrenal gland [nTPM]":"20.2","Tissue RNA - amygdala [nTPM]":"27.3","Tissue RNA - appendix [nTPM]":"21.4","Tissue RNA - basal ganglia [nTPM]":"30.2","Tissue RNA - bone marrow [nTPM]":"41.1","Tissue RNA - breast [nTPM]":"29.6","Tissue RNA - cerebellum [nTPM]":"29.4","Tissue RNA - cerebral cortex [nTPM]":"34.8","Tissue RNA - cervix [nTPM]":"28.6","Tissue RNA - choroid plexus [nTPM]":"25.8","Tissue RNA - colon [nTPM]":"30.5","Tissue RNA - duodenum [nTPM]":"21.4","Tissue RNA - endometrium 1 [nTPM]":"28.4","Tissue RNA - epididymis [nTPM]":"14.1","Tissue RNA - esophagus [nTPM]":"40.2","Tissue RNA - fallopian tube [nTPM]":"34.8","Tissue RNA - gallbladder [nTPM]":"13.6","Tissue RNA - heart muscle [nTPM]":"27.4","Tissue RNA - hippocampal formation [nTPM]":"27.1","Tissue RNA - hypothalamus [nTPM]":"29.3","Tissue RNA - kidney [nTPM]":"36.6","Tissue RNA - liver [nTPM]":"20.6","Tissue RNA - lung [nTPM]":"25.8","Tissue RNA - lymph node [nTPM]":"31.1","Tissue RNA - medulla oblongata [nTPM]":"31.1","Tissue RNA - midbrain [nTPM]":"28.1","Tissue RNA - ovary [nTPM]":"27.1","Tissue RNA - pancreas [nTPM]":"29.6","Tissue RNA - parathyroid gland [nTPM]":"23.1","Tissue RNA - pituitary gland [nTPM]":"24.3","Tissue RNA - placenta [nTPM]":"18.2","Tissue RNA - pons [nTPM]":"29.0","Tissue RNA - prostate [nTPM]":"32.3","Tissue RNA - rectum [nTPM]":"11.1","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"34.1","Tissue RNA - seminal vesicle [nTPM]":"14.2","Tissue RNA - skeletal muscle [nTPM]":"31.6","Tissue RNA - skin 1 [nTPM]":"34.9","Tissue RNA - small intestine [nTPM]":"27.6","Tissue RNA - smooth muscle [nTPM]":"13.0","Tissue RNA - spinal cord [nTPM]":"28.6","Tissue RNA - spleen [nTPM]":"38.9","Tissue RNA - stomach 1 [nTPM]":"31.8","Tissue RNA - testis [nTPM]":"12.7","Tissue RNA - thalamus [nTPM]":"28.7","Tissue RNA - thymus [nTPM]":"28.4","Tissue RNA - thyroid gland [nTPM]":"38.0","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"22.1","Tissue RNA - urinary bladder [nTPM]":"26.1","Tissue RNA - vagina [nTPM]":"27.1","Tissue RNA - white matter [nTPM]":"29.9","Cell RNA - A-431 [nTPM]":"60.0","Cell RNA - A549 [nTPM]":"36.6","Cell RNA - AF22 [nTPM]":"25.6","Cell RNA - AN3-CA [nTPM]":"50.2","Cell RNA - ASC diff [nTPM]":"8.7","Cell RNA - ASC TERT1 [nTPM]":"24.2","Cell RNA - BEWO [nTPM]":"64.5","Cell RNA - BJ [nTPM]":"29.0","Cell RNA - BJ hTERT+ [nTPM]":"30.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.7","Cell RNA - CACO-2 [nTPM]":"30.7","Cell RNA - CAPAN-2 [nTPM]":"121.4","Cell RNA - Daudi [nTPM]":"58.2","Cell RNA - EFO-21 [nTPM]":"72.9","Cell RNA - fHDF\/TERT166 [nTPM]":"30.2","Cell RNA - GAMG [nTPM]":"20.8","Cell RNA - HaCaT [nTPM]":"43.6","Cell RNA - HAP1 [nTPM]":"21.9","Cell RNA - HBEC3-KT [nTPM]":"56.2","Cell RNA - HBF TERT88 [nTPM]":"21.5","Cell RNA - HDLM-2 [nTPM]":"40.4","Cell RNA - HEK 293 [nTPM]":"33.7","Cell RNA - HEL [nTPM]":"46.7","Cell RNA - HeLa [nTPM]":"36.7","Cell RNA - Hep G2 [nTPM]":"45.1","Cell RNA - HHSteC [nTPM]":"89.4","Cell RNA - HL-60 [nTPM]":"66.8","Cell RNA - HMC-1 [nTPM]":"94.6","Cell RNA - HSkMC [nTPM]":"44.7","Cell RNA - hTCEpi [nTPM]":"32.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.8","Cell RNA - hTERT-HME1 [nTPM]":"31.0","Cell RNA - hTERT-RPE1 [nTPM]":"29.8","Cell RNA - HUVEC TERT2 [nTPM]":"49.1","Cell RNA - JURKAT [nTPM]":"56.8","Cell RNA - K-562 [nTPM]":"94.4","Cell RNA - Karpas-707 [nTPM]":"64.2","Cell RNA - LHCN-M2 [nTPM]":"27.1","Cell RNA - MCF7 [nTPM]":"119.3","Cell RNA - MOLT-4 [nTPM]":"88.0","Cell RNA - NB-4 [nTPM]":"88.3","Cell RNA - NTERA-2 [nTPM]":"30.7","Cell RNA - OE19 [nTPM]":"62.6","Cell RNA - PC-3 [nTPM]":"82.0","Cell RNA - REH [nTPM]":"73.5","Cell RNA - RH-30 [nTPM]":"26.1","Cell RNA - RPMI-8226 [nTPM]":"101.9","Cell RNA - RPTEC TERT1 [nTPM]":"41.5","Cell RNA - RT4 [nTPM]":"39.8","Cell RNA - SCLC-21H [nTPM]":"21.0","Cell RNA - SH-SY5Y [nTPM]":"43.6","Cell RNA - SiHa [nTPM]":"30.3","Cell RNA - SK-BR-3 [nTPM]":"38.2","Cell RNA - SK-MEL-30 [nTPM]":"70.4","Cell RNA - SuSa [nTPM]":"17.1","Cell RNA - T-47d [nTPM]":"54.1","Cell RNA - THP-1 [nTPM]":"134.8","Cell RNA - TIME [nTPM]":"49.1","Cell RNA - U-138 MG [nTPM]":"25.4","Cell RNA - U-2 OS [nTPM]":"27.9","Cell RNA - U-2197 [nTPM]":"63.3","Cell RNA - U-251 MG [nTPM]":"47.6","Cell RNA - U-266\/70 [nTPM]":"73.5","Cell RNA - U-266\/84 [nTPM]":"86.9","Cell RNA - U-698 [nTPM]":"87.7","Cell RNA - U-87 MG [nTPM]":"37.6","Cell RNA - U-937 [nTPM]":"82.3","Cell RNA - WM-115 [nTPM]":"52.2","Blood RNA - basophil [nTPM]":"48.5","Blood RNA - classical monocyte [nTPM]":"29.4","Blood RNA - eosinophil [nTPM]":"52.2","Blood RNA - gdT-cell [nTPM]":"23.9","Blood RNA - intermediate monocyte [nTPM]":"32.7","Blood RNA - MAIT T-cell [nTPM]":"20.4","Blood RNA - memory B-cell [nTPM]":"41.7","Blood RNA - memory CD4 T-cell [nTPM]":"27.2","Blood RNA - memory CD8 T-cell [nTPM]":"26.5","Blood RNA - myeloid DC [nTPM]":"34.2","Blood RNA - naive B-cell [nTPM]":"41.4","Blood RNA - naive CD4 T-cell [nTPM]":"27.1","Blood RNA - naive CD8 T-cell [nTPM]":"26.6","Blood RNA - neutrophil [nTPM]":"13.4","Blood RNA - NK-cell [nTPM]":"33.3","Blood RNA - non-classical monocyte [nTPM]":"24.6","Blood RNA - plasmacytoid DC [nTPM]":"54.2","Blood RNA - T-reg [nTPM]":"40.5","Blood RNA - total PBMC [nTPM]":"29.0","Brain RNA - amygdala [nTPM]":"27.3","Brain RNA - basal ganglia [nTPM]":"30.2","Brain RNA - cerebellum [nTPM]":"29.4","Brain RNA - cerebral cortex [nTPM]":"34.8","Brain RNA - hippocampal formation [nTPM]":"27.1","Brain RNA - hypothalamus [nTPM]":"29.3","Brain RNA - medulla oblongata [nTPM]":"31.1","Brain RNA - midbrain [nTPM]":"28.1","Brain RNA - pons [nTPM]":"29.0","Brain RNA - spinal cord [nTPM]":"28.6","Brain RNA - thalamus [nTPM]":"28.7","Brain RNA - white matter [nTPM]":"29.9","Single Cell Type RNA - Adipocytes [nTPM]":"33.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.9","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"28.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"77.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"10.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"39.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.5","Single Cell Type RNA - dendritic cells [nTPM]":"24.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"76.3","Single Cell Type RNA - Ductal cells [nTPM]":"44.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.7","Single Cell Type RNA - Endothelial cells [nTPM]":"35.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.2","Single Cell Type RNA - Erythroid cells [nTPM]":"45.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"57.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.3","Single Cell Type RNA - Fibroblasts [nTPM]":"26.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.7","Single Cell Type RNA - granulocytes [nTPM]":"31.8","Single Cell Type RNA - Granulosa cells [nTPM]":"31.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"16.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"63.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.0","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"44.5","Single Cell Type RNA - Langerhans cells [nTPM]":"27.8","Single Cell Type RNA - Late spermatids [nTPM]":"11.1","Single Cell Type RNA - Leydig cells [nTPM]":"30.4","Single Cell Type RNA - Macrophages [nTPM]":"34.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"57.8","Single Cell Type RNA - Muller glia cells [nTPM]":"27.6","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.3","Single Cell Type RNA - Paneth cells [nTPM]":"44.4","Single Cell Type RNA - Peritubular cells [nTPM]":"19.2","Single Cell Type RNA - Plasma cells [nTPM]":"27.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"56.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"70.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"57.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"20.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"45.6","Single Cell Type RNA - T-cells [nTPM]":"29.4","Single Cell Type RNA - Theca cells [nTPM]":"28.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.9","Single Cell Type RNA - Urothelial cells [nTPM]":"27.1"},{"Gene":"RFXAP","Gene synonym":[],"Ensembl":"ENSG00000133111","Gene description":"Regulatory factor X associated protein","Uniprot":["O00287"],"Chromosome":"13","Position":"36819222-36829104","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032035"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA032035":"AB_2674120"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.91e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"3.4","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"4.7","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"6.3","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"3.1","Tissue RNA - endometrium 1 [nTPM]":"6.8","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"3.5","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"6.7","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"7.0","Tissue RNA - pancreas [nTPM]":"4.6","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"3.7","Tissue RNA - pons [nTPM]":"3.5","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"5.5","Tissue RNA - salivary gland [nTPM]":"4.8","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"4.4","Tissue RNA - smooth muscle [nTPM]":"5.8","Tissue RNA - spinal cord [nTPM]":"4.0","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"4.2","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"8.3","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"5.4","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"7.4","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"10.4","Cell RNA - AN3-CA [nTPM]":"14.7","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"5.2","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"6.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.7","Cell RNA - CACO-2 [nTPM]":"5.2","Cell RNA - CAPAN-2 [nTPM]":"5.9","Cell RNA - Daudi [nTPM]":"32.3","Cell RNA - EFO-21 [nTPM]":"4.8","Cell RNA - fHDF\/TERT166 [nTPM]":"5.4","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"6.7","Cell RNA - HAP1 [nTPM]":"10.8","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"12.2","Cell RNA - HDLM-2 [nTPM]":"24.4","Cell RNA - HEK 293 [nTPM]":"17.9","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"8.6","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"28.7","Cell RNA - HMC-1 [nTPM]":"10.9","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.3","Cell RNA - hTERT-HME1 [nTPM]":"4.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.1","Cell RNA - HUVEC TERT2 [nTPM]":"8.3","Cell RNA - JURKAT [nTPM]":"24.4","Cell RNA - K-562 [nTPM]":"9.0","Cell RNA - Karpas-707 [nTPM]":"6.4","Cell RNA - LHCN-M2 [nTPM]":"3.3","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"28.8","Cell RNA - NB-4 [nTPM]":"20.5","Cell RNA - NTERA-2 [nTPM]":"11.1","Cell RNA - OE19 [nTPM]":"6.4","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"24.9","Cell RNA - RH-30 [nTPM]":"19.3","Cell RNA - RPMI-8226 [nTPM]":"9.8","Cell RNA - RPTEC TERT1 [nTPM]":"4.6","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"10.6","Cell RNA - SiHa [nTPM]":"5.7","Cell RNA - SK-BR-3 [nTPM]":"3.8","Cell RNA - SK-MEL-30 [nTPM]":"4.7","Cell RNA - SuSa [nTPM]":"6.3","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"16.9","Cell RNA - TIME [nTPM]":"6.5","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"6.1","Cell RNA - U-2197 [nTPM]":"9.8","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"6.0","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"24.2","Cell RNA - U-87 MG [nTPM]":"7.9","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"3.5","Brain RNA - spinal cord [nTPM]":"4.0","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"6.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"4.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.5","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.8","Single Cell Type RNA - Fibroblasts [nTPM]":"9.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"10.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"7.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"20.8","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.8","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"6.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.0","Single Cell Type RNA - Spermatocytes [nTPM]":"20.1","Single Cell Type RNA - Spermatogonia [nTPM]":"25.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"11.7","Single Cell Type RNA - Theca cells [nTPM]":"8.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"RNF168","Gene synonym":["FLJ35794"],"Ensembl":"ENSG00000163961","Gene description":"Ring finger protein 168","Uniprot":["Q8IYW5"],"Chromosome":"3","Position":"196468783-196503768","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"199.9","Late spermatids":"459.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046109"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA046109":"AB_2679540"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.29e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.31e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.6","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"20.6","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"6.0","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"5.9","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"7.4","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"5.4","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"4.9","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"13.1","Tissue RNA - skin 1 [nTPM]":"11.5","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"7.7","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"21.6","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"19.5","Cell RNA - ASC diff [nTPM]":"13.6","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"21.1","Cell RNA - BJ [nTPM]":"12.9","Cell RNA - BJ hTERT+ [nTPM]":"8.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.3","Cell RNA - CACO-2 [nTPM]":"16.6","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"22.7","Cell RNA - EFO-21 [nTPM]":"29.1","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"11.9","Cell RNA - HaCaT [nTPM]":"21.3","Cell RNA - HAP1 [nTPM]":"21.0","Cell RNA - HBEC3-KT [nTPM]":"15.4","Cell RNA - HBF TERT88 [nTPM]":"13.0","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"10.3","Cell RNA - HEL [nTPM]":"43.0","Cell RNA - HeLa [nTPM]":"22.2","Cell RNA - Hep G2 [nTPM]":"20.7","Cell RNA - HHSteC [nTPM]":"7.0","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"10.3","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"5.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.3","Cell RNA - hTERT-HME1 [nTPM]":"11.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"12.6","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"13.1","Cell RNA - Karpas-707 [nTPM]":"23.1","Cell RNA - LHCN-M2 [nTPM]":"8.7","Cell RNA - MCF7 [nTPM]":"36.4","Cell RNA - MOLT-4 [nTPM]":"44.6","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"17.6","Cell RNA - OE19 [nTPM]":"11.6","Cell RNA - PC-3 [nTPM]":"10.8","Cell RNA - REH [nTPM]":"19.7","Cell RNA - RH-30 [nTPM]":"17.2","Cell RNA - RPMI-8226 [nTPM]":"18.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.2","Cell RNA - RT4 [nTPM]":"29.2","Cell RNA - SCLC-21H [nTPM]":"12.3","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"14.6","Cell RNA - SK-BR-3 [nTPM]":"17.7","Cell RNA - SK-MEL-30 [nTPM]":"11.1","Cell RNA - SuSa [nTPM]":"10.9","Cell RNA - T-47d [nTPM]":"26.8","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"14.6","Cell RNA - U-2 OS [nTPM]":"11.4","Cell RNA - U-2197 [nTPM]":"15.7","Cell RNA - U-251 MG [nTPM]":"17.2","Cell RNA - U-266\/70 [nTPM]":"19.6","Cell RNA - U-266\/84 [nTPM]":"19.7","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"14.3","Cell RNA - U-937 [nTPM]":"15.8","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"30.0","Blood RNA - classical monocyte [nTPM]":"7.3","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"8.0","Blood RNA - MAIT T-cell [nTPM]":"10.9","Blood RNA - memory B-cell [nTPM]":"6.3","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"6.6","Blood RNA - naive B-cell [nTPM]":"6.6","Blood RNA - naive CD4 T-cell [nTPM]":"8.8","Blood RNA - naive CD8 T-cell [nTPM]":"9.4","Blood RNA - neutrophil [nTPM]":"8.0","Blood RNA - NK-cell [nTPM]":"8.7","Blood RNA - non-classical monocyte [nTPM]":"12.2","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"7.5","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"34.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.5","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"37.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"36.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - dendritic cells [nTPM]":"76.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"14.0","Single Cell Type RNA - Early spermatids [nTPM]":"199.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"33.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"33.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"27.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.0","Single Cell Type RNA - granulocytes [nTPM]":"50.1","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"25.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.5","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"98.8","Single Cell Type RNA - Late spermatids [nTPM]":"459.7","Single Cell Type RNA - Leydig cells [nTPM]":"20.2","Single Cell Type RNA - Macrophages [nTPM]":"33.9","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"38.2","Single Cell Type RNA - Muller glia cells [nTPM]":"12.7","Single Cell Type RNA - NK-cells [nTPM]":"42.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.3","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"37.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.7","Single Cell Type RNA - Spermatocytes [nTPM]":"13.8","Single Cell Type RNA - Spermatogonia [nTPM]":"54.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"55.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"126.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.7","Single Cell Type RNA - T-cells [nTPM]":"63.7","Single Cell Type RNA - Theca cells [nTPM]":"20.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.4","Single Cell Type RNA - Urothelial cells [nTPM]":"50.3"},{"Gene":"RORC","Gene synonym":["NR1F3","RORG","RZRG","TOR"],"Ensembl":"ENSG00000143365","Gene description":"RAR related orphan receptor C","Uniprot":["P51449"],"Chromosome":"1","Position":"151806071-151831845","Protein class":["Disease related genes","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"86.2","skeletal muscle":"128.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"35.2","Hepatocytes":"47.8","Proximal enterocytes":"32.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"4.1"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"MAIT T-cell":"50.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"44","RNA blood lineage specific nTPM":{"T-cells":"50.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"23.8","Karpas-707":"11.5","MOLT-4":"6.3","RPMI-8226":"6.0","SK-BR-3":"5.7","T-47d":"9.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065620"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA065620":"AB_2685521"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.83e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.94e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.9","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"9.3","Tissue RNA - duodenum [nTPM]":"11.6","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"4.6","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"21.2","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"18.8","Tissue RNA - liver [nTPM]":"86.2","Tissue RNA - lung [nTPM]":"12.7","Tissue RNA - lymph node [nTPM]":"0.9","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"59.2","Tissue RNA - parathyroid gland [nTPM]":"33.5","Tissue RNA - pituitary gland [nTPM]":"18.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"15.8","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"41.0","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"128.0","Tissue RNA - skin 1 [nTPM]":"24.7","Tissue RNA - small intestine [nTPM]":"13.9","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"19.8","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"52.7","Tissue RNA - thyroid gland [nTPM]":"26.4","Tissue RNA - tongue [nTPM]":"58.8","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"23.8","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"2.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"11.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"6.3","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"6.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"5.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"9.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"3.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"50.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"8.0","Blood RNA - memory CD8 T-cell [nTPM]":"7.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"5.8","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"5.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"8.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"47.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.2","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"6.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.3","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"SBDS","Gene synonym":["CGI-97","FLJ10917","SDS","SWDS"],"Ensembl":"ENSG00000126524","Gene description":"SBDS ribosome maturation factor","Uniprot":["Q9Y3A5"],"Chromosome":"7","Position":"66987680-66995587","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"2042.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028891"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028891":"AB_10601500"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"139.1","Tissue RNA - adrenal gland [nTPM]":"107.5","Tissue RNA - amygdala [nTPM]":"136.1","Tissue RNA - appendix [nTPM]":"57.9","Tissue RNA - basal ganglia [nTPM]":"152.1","Tissue RNA - bone marrow [nTPM]":"157.2","Tissue RNA - breast [nTPM]":"113.7","Tissue RNA - cerebellum [nTPM]":"151.2","Tissue RNA - cerebral cortex [nTPM]":"168.3","Tissue RNA - cervix [nTPM]":"97.3","Tissue RNA - choroid plexus [nTPM]":"115.8","Tissue RNA - colon [nTPM]":"143.6","Tissue RNA - duodenum [nTPM]":"127.8","Tissue RNA - endometrium 1 [nTPM]":"117.2","Tissue RNA - epididymis [nTPM]":"83.3","Tissue RNA - esophagus [nTPM]":"128.6","Tissue RNA - fallopian tube [nTPM]":"99.2","Tissue RNA - gallbladder [nTPM]":"84.9","Tissue RNA - heart muscle [nTPM]":"238.0","Tissue RNA - hippocampal formation [nTPM]":"133.1","Tissue RNA - hypothalamus [nTPM]":"148.4","Tissue RNA - kidney [nTPM]":"117.8","Tissue RNA - liver [nTPM]":"126.8","Tissue RNA - lung [nTPM]":"113.8","Tissue RNA - lymph node [nTPM]":"43.8","Tissue RNA - medulla oblongata [nTPM]":"156.2","Tissue RNA - midbrain [nTPM]":"142.3","Tissue RNA - ovary [nTPM]":"90.1","Tissue RNA - pancreas [nTPM]":"89.3","Tissue RNA - parathyroid gland [nTPM]":"145.0","Tissue RNA - pituitary gland [nTPM]":"87.4","Tissue RNA - placenta [nTPM]":"106.2","Tissue RNA - pons [nTPM]":"155.0","Tissue RNA - prostate [nTPM]":"107.9","Tissue RNA - rectum [nTPM]":"111.6","Tissue RNA - retina [nTPM]":"90.3","Tissue RNA - salivary gland [nTPM]":"80.7","Tissue RNA - seminal vesicle [nTPM]":"122.6","Tissue RNA - skeletal muscle [nTPM]":"374.0","Tissue RNA - skin 1 [nTPM]":"92.0","Tissue RNA - small intestine [nTPM]":"114.2","Tissue RNA - smooth muscle [nTPM]":"128.2","Tissue RNA - spinal cord [nTPM]":"152.6","Tissue RNA - spleen [nTPM]":"57.3","Tissue RNA - stomach 1 [nTPM]":"104.6","Tissue RNA - testis [nTPM]":"60.9","Tissue RNA - thalamus [nTPM]":"143.4","Tissue RNA - thymus [nTPM]":"38.8","Tissue RNA - thyroid gland [nTPM]":"107.0","Tissue RNA - tongue [nTPM]":"263.3","Tissue RNA - tonsil [nTPM]":"52.5","Tissue RNA - urinary bladder [nTPM]":"113.9","Tissue RNA - vagina [nTPM]":"90.7","Tissue RNA - white matter [nTPM]":"169.7","Cell RNA - A-431 [nTPM]":"168.3","Cell RNA - A549 [nTPM]":"68.9","Cell RNA - AF22 [nTPM]":"59.9","Cell RNA - AN3-CA [nTPM]":"54.6","Cell RNA - ASC diff [nTPM]":"212.7","Cell RNA - ASC TERT1 [nTPM]":"157.9","Cell RNA - BEWO [nTPM]":"67.0","Cell RNA - BJ [nTPM]":"281.4","Cell RNA - BJ hTERT+ [nTPM]":"225.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"206.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"157.1","Cell RNA - CACO-2 [nTPM]":"143.1","Cell RNA - CAPAN-2 [nTPM]":"83.0","Cell RNA - Daudi [nTPM]":"62.2","Cell RNA - EFO-21 [nTPM]":"209.7","Cell RNA - fHDF\/TERT166 [nTPM]":"253.5","Cell RNA - GAMG [nTPM]":"136.3","Cell RNA - HaCaT [nTPM]":"80.1","Cell RNA - HAP1 [nTPM]":"101.7","Cell RNA - HBEC3-KT [nTPM]":"164.3","Cell RNA - HBF TERT88 [nTPM]":"219.4","Cell RNA - HDLM-2 [nTPM]":"59.8","Cell RNA - HEK 293 [nTPM]":"136.4","Cell RNA - HEL [nTPM]":"31.1","Cell RNA - HeLa [nTPM]":"125.9","Cell RNA - Hep G2 [nTPM]":"86.6","Cell RNA - HHSteC [nTPM]":"188.9","Cell RNA - HL-60 [nTPM]":"78.1","Cell RNA - HMC-1 [nTPM]":"40.8","Cell RNA - HSkMC [nTPM]":"144.0","Cell RNA - hTCEpi [nTPM]":"215.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"157.0","Cell RNA - hTERT-HME1 [nTPM]":"269.8","Cell RNA - hTERT-RPE1 [nTPM]":"105.9","Cell RNA - HUVEC TERT2 [nTPM]":"129.2","Cell RNA - JURKAT [nTPM]":"39.7","Cell RNA - K-562 [nTPM]":"227.2","Cell RNA - Karpas-707 [nTPM]":"65.0","Cell RNA - LHCN-M2 [nTPM]":"324.2","Cell RNA - MCF7 [nTPM]":"100.0","Cell RNA - MOLT-4 [nTPM]":"41.8","Cell RNA - NB-4 [nTPM]":"112.4","Cell RNA - NTERA-2 [nTPM]":"67.2","Cell RNA - OE19 [nTPM]":"227.3","Cell RNA - PC-3 [nTPM]":"165.9","Cell RNA - REH [nTPM]":"31.3","Cell RNA - RH-30 [nTPM]":"132.6","Cell RNA - RPMI-8226 [nTPM]":"129.3","Cell RNA - RPTEC TERT1 [nTPM]":"218.1","Cell RNA - RT4 [nTPM]":"73.6","Cell RNA - SCLC-21H [nTPM]":"91.7","Cell RNA - SH-SY5Y [nTPM]":"63.7","Cell RNA - SiHa [nTPM]":"142.3","Cell RNA - SK-BR-3 [nTPM]":"235.5","Cell RNA - SK-MEL-30 [nTPM]":"194.3","Cell RNA - SuSa [nTPM]":"131.0","Cell RNA - T-47d [nTPM]":"176.2","Cell RNA - THP-1 [nTPM]":"64.8","Cell RNA - TIME [nTPM]":"176.4","Cell RNA - U-138 MG [nTPM]":"276.5","Cell RNA - U-2 OS [nTPM]":"96.7","Cell RNA - U-2197 [nTPM]":"142.5","Cell RNA - U-251 MG [nTPM]":"205.4","Cell RNA - U-266\/70 [nTPM]":"40.6","Cell RNA - U-266\/84 [nTPM]":"51.4","Cell RNA - U-698 [nTPM]":"141.0","Cell RNA - U-87 MG [nTPM]":"95.7","Cell RNA - U-937 [nTPM]":"125.5","Cell RNA - WM-115 [nTPM]":"157.4","Blood RNA - basophil [nTPM]":"75.5","Blood RNA - classical monocyte [nTPM]":"33.2","Blood RNA - eosinophil [nTPM]":"61.4","Blood RNA - gdT-cell [nTPM]":"64.7","Blood RNA - intermediate monocyte [nTPM]":"37.7","Blood RNA - MAIT T-cell [nTPM]":"81.7","Blood RNA - memory B-cell [nTPM]":"62.8","Blood RNA - memory CD4 T-cell [nTPM]":"82.7","Blood RNA - memory CD8 T-cell [nTPM]":"75.2","Blood RNA - myeloid DC [nTPM]":"33.4","Blood RNA - naive B-cell [nTPM]":"59.9","Blood RNA - naive CD4 T-cell [nTPM]":"104.4","Blood RNA - naive CD8 T-cell [nTPM]":"85.7","Blood RNA - neutrophil [nTPM]":"13.0","Blood RNA - NK-cell [nTPM]":"51.8","Blood RNA - non-classical monocyte [nTPM]":"35.1","Blood RNA - plasmacytoid DC [nTPM]":"45.4","Blood RNA - T-reg [nTPM]":"80.2","Blood RNA - total PBMC [nTPM]":"62.2","Brain RNA - amygdala [nTPM]":"136.1","Brain RNA - basal ganglia [nTPM]":"152.1","Brain RNA - cerebellum [nTPM]":"151.2","Brain RNA - cerebral cortex [nTPM]":"168.3","Brain RNA - hippocampal formation [nTPM]":"133.1","Brain RNA - hypothalamus [nTPM]":"148.4","Brain RNA - medulla oblongata [nTPM]":"156.2","Brain RNA - midbrain [nTPM]":"142.3","Brain RNA - pons [nTPM]":"155.0","Brain RNA - spinal cord [nTPM]":"152.6","Brain RNA - thalamus [nTPM]":"143.4","Brain RNA - white matter [nTPM]":"169.7","Single Cell Type RNA - Adipocytes [nTPM]":"169.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"304.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"128.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"101.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"464.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"466.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"213.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"145.7","Single Cell Type RNA - Bipolar cells [nTPM]":"73.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"118.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"154.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"286.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"108.7","Single Cell Type RNA - Club cells [nTPM]":"160.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"92.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"130.5","Single Cell Type RNA - dendritic cells [nTPM]":"98.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"270.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"262.2","Single Cell Type RNA - Ductal cells [nTPM]":"177.4","Single Cell Type RNA - Early spermatids [nTPM]":"583.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"93.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"131.2","Single Cell Type RNA - Endothelial cells [nTPM]":"153.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"101.9","Single Cell Type RNA - Erythroid cells [nTPM]":"51.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"165.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"232.1","Single Cell Type RNA - Fibroblasts [nTPM]":"197.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"96.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"128.2","Single Cell Type RNA - granulocytes [nTPM]":"150.0","Single Cell Type RNA - Granulosa cells [nTPM]":"29.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"138.5","Single Cell Type RNA - Hepatocytes [nTPM]":"102.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"107.0","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"221.9","Single Cell Type RNA - Ionocytes [nTPM]":"142.4","Single Cell Type RNA - Kupffer cells [nTPM]":"47.2","Single Cell Type RNA - Langerhans cells [nTPM]":"238.1","Single Cell Type RNA - Late spermatids [nTPM]":"2042.9","Single Cell Type RNA - Leydig cells [nTPM]":"127.1","Single Cell Type RNA - Macrophages [nTPM]":"74.8","Single Cell Type RNA - Melanocytes [nTPM]":"256.1","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"66.5","Single Cell Type RNA - Muller glia cells [nTPM]":"161.9","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"300.0","Single Cell Type RNA - Paneth cells [nTPM]":"242.2","Single Cell Type RNA - Peritubular cells [nTPM]":"168.5","Single Cell Type RNA - Plasma cells [nTPM]":"117.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"267.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"359.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"264.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"75.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.8","Single Cell Type RNA - Sertoli cells [nTPM]":"164.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"512.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"266.2","Single Cell Type RNA - Spermatocytes [nTPM]":"86.3","Single Cell Type RNA - Spermatogonia [nTPM]":"47.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"129.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"430.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"398.5","Single Cell Type RNA - T-cells [nTPM]":"144.5","Single Cell Type RNA - Theca cells [nTPM]":"132.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"165.4","Single Cell Type RNA - Urothelial cells [nTPM]":"318.5"},{"Gene":"SERPING1","Gene synonym":["C1-INH","C1IN","C1INH","C1NH","HAE1","HAE2"],"Ensembl":"ENSG00000149131","Gene description":"Serpin family G member 1","Uniprot":["P05155"],"Chromosome":"11","Position":"57597387-57619171","Protein class":["Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Blood coagulation","Complement pathway","Fibrinolysis","Hemostasis","Immunity","Innate immunity"],"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"2622.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cholangiocytes":"726.4","Ductal cells":"604.0","Fibroblasts":"793.6","Hepatocytes":"2530.0","Leydig cells":"735.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"609.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"65.2","plasmacytoid DC":"60.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"243","RNA blood lineage specific nTPM":{"dendritic cells":"60.6","granulocytes":"65.2","monocytes":"25.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"ASC diff":"1372.2","ASC TERT1":"694.9","HSkMC":"1159.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"194.1"},"Antibody":["CAB026161","HPA048738"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000000000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026161":null,"HPA048738":"AB_2680505"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.96e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.03e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"971.5","Tissue RNA - adrenal gland [nTPM]":"144.2","Tissue RNA - amygdala [nTPM]":"27.4","Tissue RNA - appendix [nTPM]":"90.0","Tissue RNA - basal ganglia [nTPM]":"27.5","Tissue RNA - bone marrow [nTPM]":"10.9","Tissue RNA - breast [nTPM]":"733.0","Tissue RNA - cerebellum [nTPM]":"27.1","Tissue RNA - cerebral cortex [nTPM]":"36.0","Tissue RNA - cervix [nTPM]":"629.4","Tissue RNA - choroid plexus [nTPM]":"53.4","Tissue RNA - colon [nTPM]":"358.7","Tissue RNA - duodenum [nTPM]":"52.0","Tissue RNA - endometrium 1 [nTPM]":"616.7","Tissue RNA - epididymis [nTPM]":"163.3","Tissue RNA - esophagus [nTPM]":"162.0","Tissue RNA - fallopian tube [nTPM]":"793.2","Tissue RNA - gallbladder [nTPM]":"533.0","Tissue RNA - heart muscle [nTPM]":"547.1","Tissue RNA - hippocampal formation [nTPM]":"26.2","Tissue RNA - hypothalamus [nTPM]":"34.8","Tissue RNA - kidney [nTPM]":"337.3","Tissue RNA - liver [nTPM]":"2622.4","Tissue RNA - lung [nTPM]":"785.0","Tissue RNA - lymph node [nTPM]":"147.6","Tissue RNA - medulla oblongata [nTPM]":"67.4","Tissue RNA - midbrain [nTPM]":"34.7","Tissue RNA - ovary [nTPM]":"918.3","Tissue RNA - pancreas [nTPM]":"267.5","Tissue RNA - parathyroid gland [nTPM]":"55.2","Tissue RNA - pituitary gland [nTPM]":"138.2","Tissue RNA - placenta [nTPM]":"198.9","Tissue RNA - pons [nTPM]":"34.2","Tissue RNA - prostate [nTPM]":"329.3","Tissue RNA - rectum [nTPM]":"97.0","Tissue RNA - retina [nTPM]":"34.5","Tissue RNA - salivary gland [nTPM]":"250.5","Tissue RNA - seminal vesicle [nTPM]":"258.1","Tissue RNA - skeletal muscle [nTPM]":"151.8","Tissue RNA - skin 1 [nTPM]":"293.5","Tissue RNA - small intestine [nTPM]":"283.5","Tissue RNA - smooth muscle [nTPM]":"226.8","Tissue RNA - spinal cord [nTPM]":"42.3","Tissue RNA - spleen [nTPM]":"240.7","Tissue RNA - stomach 1 [nTPM]":"344.8","Tissue RNA - testis [nTPM]":"50.6","Tissue RNA - thalamus [nTPM]":"37.2","Tissue RNA - thymus [nTPM]":"36.1","Tissue RNA - thyroid gland [nTPM]":"338.2","Tissue RNA - tongue [nTPM]":"173.4","Tissue RNA - tonsil [nTPM]":"64.4","Tissue RNA - urinary bladder [nTPM]":"555.9","Tissue RNA - vagina [nTPM]":"519.8","Tissue RNA - white matter [nTPM]":"35.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"48.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1372.2","Cell RNA - ASC TERT1 [nTPM]":"694.9","Cell RNA - BEWO [nTPM]":"7.3","Cell RNA - BJ [nTPM]":"74.2","Cell RNA - BJ hTERT+ [nTPM]":"57.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.7","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"96.7","Cell RNA - fHDF\/TERT166 [nTPM]":"42.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"9.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"33.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"170.3","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"5.4","Cell RNA - HSkMC [nTPM]":"1159.0","Cell RNA - hTCEpi [nTPM]":"15.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.7","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"46.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"4.3","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"14.4","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"41.8","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"21.2","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"18.3","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"25.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"65.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"11.5","Blood RNA - plasmacytoid DC [nTPM]":"60.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"5.7","Brain RNA - amygdala [nTPM]":"27.4","Brain RNA - basal ganglia [nTPM]":"27.5","Brain RNA - cerebellum [nTPM]":"27.1","Brain RNA - cerebral cortex [nTPM]":"36.0","Brain RNA - hippocampal formation [nTPM]":"26.2","Brain RNA - hypothalamus [nTPM]":"34.8","Brain RNA - medulla oblongata [nTPM]":"67.4","Brain RNA - midbrain [nTPM]":"34.7","Brain RNA - pons [nTPM]":"34.2","Brain RNA - spinal cord [nTPM]":"42.3","Brain RNA - thalamus [nTPM]":"37.2","Brain RNA - white matter [nTPM]":"35.1","Single Cell Type RNA - Adipocytes [nTPM]":"162.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"110.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"8.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"75.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"61.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"57.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"726.4","Single Cell Type RNA - Club cells [nTPM]":"57.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"158.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.1","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"604.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"76.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"297.4","Single Cell Type RNA - Endothelial cells [nTPM]":"150.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"69.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"93.4","Single Cell Type RNA - Fibroblasts [nTPM]":"793.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.6","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"260.5","Single Cell Type RNA - Hepatocytes [nTPM]":"2530.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"118.9","Single Cell Type RNA - Langerhans cells [nTPM]":"94.2","Single Cell Type RNA - Late spermatids [nTPM]":"25.6","Single Cell Type RNA - Leydig cells [nTPM]":"735.3","Single Cell Type RNA - Macrophages [nTPM]":"46.9","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"10.4","Single Cell Type RNA - Muller glia cells [nTPM]":"57.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"228.7","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"53.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.5","Single Cell Type RNA - Sertoli cells [nTPM]":"269.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"143.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"259.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - T-cells [nTPM]":"16.8","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"37.4"},{"Gene":"SH2D1A","Gene synonym":["DSHP","EBVS","IMD5","LYP","MTCP1","SAP","XLP","XLPD"],"Ensembl":"ENSG00000183918","Gene description":"SH2 domain containing 1A","Uniprot":["O60880"],"Chromosome":"X","Position":"124227868-124373197","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"48","RNA tissue specific nTPM":{"lymphoid tissue":"262.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"dendritic cells":"77.6","NK-cells":"138.0","T-cells":"108.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"54","RNA blood cell specific nTPM":{"gdT-cell":"120.2","MAIT T-cell":"162.9","memory CD4 T-cell":"90.4","memory CD8 T-cell":"175.8","naive CD4 T-cell":"91.2","naive CD8 T-cell":"108.3","NK-cell":"162.2","T-reg":"125.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"70","RNA blood lineage specific nTPM":{"NK-cells":"162.2","T-cells":"175.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HDLM-2":"101.1","JURKAT":"193.0","Karpas-707":"201.3","MOLT-4":"257.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072265"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA072265":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.03e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"1.2","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"1.6","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"38.4","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"262.5","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"16.6","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"15.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"101.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"193.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"201.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"257.2","Cell RNA - NB-4 [nTPM]":"4.6","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"32.7","Cell RNA - U-266\/84 [nTPM]":"33.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"120.2","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"162.9","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"90.4","Blood RNA - memory CD8 T-cell [nTPM]":"175.8","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"91.2","Blood RNA - naive CD8 T-cell [nTPM]":"108.3","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"162.2","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"125.3","Blood RNA - total PBMC [nTPM]":"91.3","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"77.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"138.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"14.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"108.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SLC35C1","Gene synonym":["FLJ11320","FUCT1"],"Ensembl":"ENSG00000181830","Gene description":"Solute carrier family 35 member C1","Uniprot":["Q96A29"],"Chromosome":"11","Position":"45804072-45813016","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Sugar transport","Transport"],"Molecular function":null,"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"84.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"50.6","Distal enterocytes":"54.6","Pancreatic endocrine cells":"50.6","Paneth cells":"54.0","Proximal enterocytes":"58.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064001"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA064001":"AB_2685171"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.68e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.64e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.2","Tissue RNA - adrenal gland [nTPM]":"7.3","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"19.8","Tissue RNA - cerebellum [nTPM]":"7.0","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"19.8","Tissue RNA - duodenum [nTPM]":"24.4","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"41.5","Tissue RNA - fallopian tube [nTPM]":"7.3","Tissue RNA - gallbladder [nTPM]":"12.2","Tissue RNA - heart muscle [nTPM]":"9.0","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"7.2","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"84.5","Tissue RNA - lung [nTPM]":"10.2","Tissue RNA - lymph node [nTPM]":"6.6","Tissue RNA - medulla oblongata [nTPM]":"8.2","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"13.4","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"15.0","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"26.1","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"6.8","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"24.1","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"6.5","Tissue RNA - spleen [nTPM]":"8.4","Tissue RNA - stomach 1 [nTPM]":"18.5","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"8.8","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"6.6","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"10.0","Tissue RNA - urinary bladder [nTPM]":"13.8","Tissue RNA - vagina [nTPM]":"14.9","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"25.8","Cell RNA - AF22 [nTPM]":"6.3","Cell RNA - AN3-CA [nTPM]":"16.3","Cell RNA - ASC diff [nTPM]":"19.9","Cell RNA - ASC TERT1 [nTPM]":"19.8","Cell RNA - BEWO [nTPM]":"19.5","Cell RNA - BJ [nTPM]":"22.1","Cell RNA - BJ hTERT+ [nTPM]":"20.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.4","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"15.2","Cell RNA - Daudi [nTPM]":"10.4","Cell RNA - EFO-21 [nTPM]":"9.9","Cell RNA - fHDF\/TERT166 [nTPM]":"27.3","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"26.0","Cell RNA - HAP1 [nTPM]":"13.4","Cell RNA - HBEC3-KT [nTPM]":"13.6","Cell RNA - HBF TERT88 [nTPM]":"6.5","Cell RNA - HDLM-2 [nTPM]":"24.8","Cell RNA - HEK 293 [nTPM]":"14.5","Cell RNA - HEL [nTPM]":"5.9","Cell RNA - HeLa [nTPM]":"20.4","Cell RNA - Hep G2 [nTPM]":"20.6","Cell RNA - HHSteC [nTPM]":"42.6","Cell RNA - HL-60 [nTPM]":"11.4","Cell RNA - HMC-1 [nTPM]":"16.2","Cell RNA - HSkMC [nTPM]":"23.8","Cell RNA - hTCEpi [nTPM]":"16.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.2","Cell RNA - hTERT-HME1 [nTPM]":"11.1","Cell RNA - hTERT-RPE1 [nTPM]":"16.2","Cell RNA - HUVEC TERT2 [nTPM]":"17.6","Cell RNA - JURKAT [nTPM]":"10.3","Cell RNA - K-562 [nTPM]":"13.3","Cell RNA - Karpas-707 [nTPM]":"13.8","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"21.8","Cell RNA - MOLT-4 [nTPM]":"5.9","Cell RNA - NB-4 [nTPM]":"9.0","Cell RNA - NTERA-2 [nTPM]":"27.5","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"34.6","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"10.5","Cell RNA - RPMI-8226 [nTPM]":"21.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.1","Cell RNA - RT4 [nTPM]":"25.4","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"8.6","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"16.3","Cell RNA - SK-MEL-30 [nTPM]":"9.5","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"13.7","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"25.7","Cell RNA - U-138 MG [nTPM]":"25.0","Cell RNA - U-2 OS [nTPM]":"14.7","Cell RNA - U-2197 [nTPM]":"46.1","Cell RNA - U-251 MG [nTPM]":"15.6","Cell RNA - U-266\/70 [nTPM]":"9.8","Cell RNA - U-266\/84 [nTPM]":"26.9","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"18.5","Cell RNA - U-937 [nTPM]":"14.4","Cell RNA - WM-115 [nTPM]":"14.2","Blood RNA - basophil [nTPM]":"9.7","Blood RNA - classical monocyte [nTPM]":"11.6","Blood RNA - eosinophil [nTPM]":"12.5","Blood RNA - gdT-cell [nTPM]":"11.0","Blood RNA - intermediate monocyte [nTPM]":"11.9","Blood RNA - MAIT T-cell [nTPM]":"12.3","Blood RNA - memory B-cell [nTPM]":"5.0","Blood RNA - memory CD4 T-cell [nTPM]":"18.0","Blood RNA - memory CD8 T-cell [nTPM]":"14.7","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"3.7","Blood RNA - naive CD4 T-cell [nTPM]":"9.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.0","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"5.6","Blood RNA - non-classical monocyte [nTPM]":"8.7","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"13.0","Blood RNA - total PBMC [nTPM]":"10.1","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"7.0","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"7.2","Brain RNA - medulla oblongata [nTPM]":"8.2","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"6.5","Brain RNA - thalamus [nTPM]":"8.8","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"6.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"50.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"26.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.8","Single Cell Type RNA - dendritic cells [nTPM]":"6.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"54.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"41.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.0","Single Cell Type RNA - Fibroblasts [nTPM]":"10.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"5.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"42.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"9.5","Single Cell Type RNA - Muller glia cells [nTPM]":"2.8","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.6","Single Cell Type RNA - Paneth cells [nTPM]":"54.0","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"13.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"58.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.3","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.4","Single Cell Type RNA - Urothelial cells [nTPM]":"20.1"},{"Gene":"SMARCD2","Gene synonym":["BAF60B","CRACD2","PRO2451","Rsc6p"],"Ensembl":"ENSG00000108604","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2","Uniprot":["Q92925"],"Chromosome":"17","Position":"63832081-63843065","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Theca cells":"101.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059934","HPA061348"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA059934":"AB_2684170","HPA061348":"AB_2684486"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.51e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"53.8","Tissue RNA - adrenal gland [nTPM]":"55.2","Tissue RNA - amygdala [nTPM]":"23.3","Tissue RNA - appendix [nTPM]":"44.6","Tissue RNA - basal ganglia [nTPM]":"28.1","Tissue RNA - bone marrow [nTPM]":"71.6","Tissue RNA - breast [nTPM]":"65.9","Tissue RNA - cerebellum [nTPM]":"35.5","Tissue RNA - cerebral cortex [nTPM]":"28.5","Tissue RNA - cervix [nTPM]":"48.0","Tissue RNA - choroid plexus [nTPM]":"29.1","Tissue RNA - colon [nTPM]":"49.9","Tissue RNA - duodenum [nTPM]":"51.1","Tissue RNA - endometrium 1 [nTPM]":"37.4","Tissue RNA - epididymis [nTPM]":"58.5","Tissue RNA - esophagus [nTPM]":"71.3","Tissue RNA - fallopian tube [nTPM]":"52.9","Tissue RNA - gallbladder [nTPM]":"33.1","Tissue RNA - heart muscle [nTPM]":"31.2","Tissue RNA - hippocampal formation [nTPM]":"22.9","Tissue RNA - hypothalamus [nTPM]":"23.2","Tissue RNA - kidney [nTPM]":"26.4","Tissue RNA - liver [nTPM]":"54.9","Tissue RNA - lung [nTPM]":"46.7","Tissue RNA - lymph node [nTPM]":"66.0","Tissue RNA - medulla oblongata [nTPM]":"27.7","Tissue RNA - midbrain [nTPM]":"26.7","Tissue RNA - ovary [nTPM]":"38.3","Tissue RNA - pancreas [nTPM]":"89.5","Tissue RNA - parathyroid gland [nTPM]":"42.8","Tissue RNA - pituitary gland [nTPM]":"36.7","Tissue RNA - placenta [nTPM]":"47.8","Tissue RNA - pons [nTPM]":"27.0","Tissue RNA - prostate [nTPM]":"52.7","Tissue RNA - rectum [nTPM]":"46.6","Tissue RNA - retina [nTPM]":"17.6","Tissue RNA - salivary gland [nTPM]":"78.0","Tissue RNA - seminal vesicle [nTPM]":"49.0","Tissue RNA - skeletal muscle [nTPM]":"25.3","Tissue RNA - skin 1 [nTPM]":"97.0","Tissue RNA - small intestine [nTPM]":"49.8","Tissue RNA - smooth muscle [nTPM]":"32.4","Tissue RNA - spinal cord [nTPM]":"25.5","Tissue RNA - spleen [nTPM]":"60.6","Tissue RNA - stomach 1 [nTPM]":"68.2","Tissue RNA - testis [nTPM]":"42.7","Tissue RNA - thalamus [nTPM]":"25.6","Tissue RNA - thymus [nTPM]":"70.2","Tissue RNA - thyroid gland [nTPM]":"33.8","Tissue RNA - tongue [nTPM]":"34.2","Tissue RNA - tonsil [nTPM]":"70.1","Tissue RNA - urinary bladder [nTPM]":"52.3","Tissue RNA - vagina [nTPM]":"55.9","Tissue RNA - white matter [nTPM]":"31.7","Cell RNA - A-431 [nTPM]":"142.9","Cell RNA - A549 [nTPM]":"87.9","Cell RNA - AF22 [nTPM]":"21.3","Cell RNA - AN3-CA [nTPM]":"93.0","Cell RNA - ASC diff [nTPM]":"133.6","Cell RNA - ASC TERT1 [nTPM]":"196.1","Cell RNA - BEWO [nTPM]":"139.7","Cell RNA - BJ [nTPM]":"52.5","Cell RNA - BJ hTERT+ [nTPM]":"64.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"97.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"61.7","Cell RNA - CACO-2 [nTPM]":"101.7","Cell RNA - CAPAN-2 [nTPM]":"76.8","Cell RNA - Daudi [nTPM]":"163.0","Cell RNA - EFO-21 [nTPM]":"32.5","Cell RNA - fHDF\/TERT166 [nTPM]":"79.0","Cell RNA - GAMG [nTPM]":"43.9","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"65.7","Cell RNA - HBEC3-KT [nTPM]":"99.1","Cell RNA - HBF TERT88 [nTPM]":"57.3","Cell RNA - HDLM-2 [nTPM]":"61.1","Cell RNA - HEK 293 [nTPM]":"169.5","Cell RNA - HEL [nTPM]":"109.3","Cell RNA - HeLa [nTPM]":"40.3","Cell RNA - Hep G2 [nTPM]":"141.7","Cell RNA - HHSteC [nTPM]":"102.3","Cell RNA - HL-60 [nTPM]":"159.5","Cell RNA - HMC-1 [nTPM]":"128.9","Cell RNA - HSkMC [nTPM]":"154.3","Cell RNA - hTCEpi [nTPM]":"122.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.3","Cell RNA - hTERT-HME1 [nTPM]":"42.1","Cell RNA - hTERT-RPE1 [nTPM]":"56.4","Cell RNA - HUVEC TERT2 [nTPM]":"78.3","Cell RNA - JURKAT [nTPM]":"110.8","Cell RNA - K-562 [nTPM]":"89.5","Cell RNA - Karpas-707 [nTPM]":"101.7","Cell RNA - LHCN-M2 [nTPM]":"57.2","Cell RNA - MCF7 [nTPM]":"279.1","Cell RNA - MOLT-4 [nTPM]":"203.8","Cell RNA - NB-4 [nTPM]":"132.3","Cell RNA - NTERA-2 [nTPM]":"51.3","Cell RNA - OE19 [nTPM]":"202.0","Cell RNA - PC-3 [nTPM]":"96.9","Cell RNA - REH [nTPM]":"195.0","Cell RNA - RH-30 [nTPM]":"77.8","Cell RNA - RPMI-8226 [nTPM]":"185.0","Cell RNA - RPTEC TERT1 [nTPM]":"66.9","Cell RNA - RT4 [nTPM]":"96.0","Cell RNA - SCLC-21H [nTPM]":"80.2","Cell RNA - SH-SY5Y [nTPM]":"145.9","Cell RNA - SiHa [nTPM]":"79.2","Cell RNA - SK-BR-3 [nTPM]":"228.4","Cell RNA - SK-MEL-30 [nTPM]":"97.1","Cell RNA - SuSa [nTPM]":"69.3","Cell RNA - T-47d [nTPM]":"212.2","Cell RNA - THP-1 [nTPM]":"121.7","Cell RNA - TIME [nTPM]":"58.4","Cell RNA - U-138 MG [nTPM]":"67.7","Cell RNA - U-2 OS [nTPM]":"52.5","Cell RNA - U-2197 [nTPM]":"61.4","Cell RNA - U-251 MG [nTPM]":"90.7","Cell RNA - U-266\/70 [nTPM]":"119.8","Cell RNA - U-266\/84 [nTPM]":"113.2","Cell RNA - U-698 [nTPM]":"113.5","Cell RNA - U-87 MG [nTPM]":"54.1","Cell RNA - U-937 [nTPM]":"129.6","Cell RNA - WM-115 [nTPM]":"50.4","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"9.1","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"9.4","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"7.2","Blood RNA - memory CD4 T-cell [nTPM]":"9.9","Blood RNA - memory CD8 T-cell [nTPM]":"9.8","Blood RNA - myeloid DC [nTPM]":"12.1","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"6.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.5","Blood RNA - neutrophil [nTPM]":"10.8","Blood RNA - NK-cell [nTPM]":"8.0","Blood RNA - non-classical monocyte [nTPM]":"10.0","Blood RNA - plasmacytoid DC [nTPM]":"10.1","Blood RNA - T-reg [nTPM]":"11.5","Blood RNA - total PBMC [nTPM]":"6.0","Brain RNA - amygdala [nTPM]":"23.3","Brain RNA - basal ganglia [nTPM]":"28.1","Brain RNA - cerebellum [nTPM]":"35.5","Brain RNA - cerebral cortex [nTPM]":"28.5","Brain RNA - hippocampal formation [nTPM]":"22.9","Brain RNA - hypothalamus [nTPM]":"23.2","Brain RNA - medulla oblongata [nTPM]":"27.7","Brain RNA - midbrain [nTPM]":"26.7","Brain RNA - pons [nTPM]":"27.0","Brain RNA - spinal cord [nTPM]":"25.5","Brain RNA - thalamus [nTPM]":"25.6","Brain RNA - white matter [nTPM]":"31.7","Single Cell Type RNA - Adipocytes [nTPM]":"14.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"42.4","Single Cell Type RNA - Astrocytes [nTPM]":"19.9","Single Cell Type RNA - B-cells [nTPM]":"18.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"47.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"25.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.9","Single Cell Type RNA - dendritic cells [nTPM]":"21.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.2","Single Cell Type RNA - Fibroblasts [nTPM]":"25.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.7","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"88.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"83.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.0","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"42.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"36.9","Single Cell Type RNA - Langerhans cells [nTPM]":"19.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"49.4","Single Cell Type RNA - Macrophages [nTPM]":"23.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"16.9","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.0","Single Cell Type RNA - Paneth cells [nTPM]":"26.2","Single Cell Type RNA - Peritubular cells [nTPM]":"30.9","Single Cell Type RNA - Plasma cells [nTPM]":"12.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.6","Single Cell Type RNA - Spermatocytes [nTPM]":"12.3","Single Cell Type RNA - Spermatogonia [nTPM]":"22.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"52.9","Single Cell Type RNA - T-cells [nTPM]":"16.7","Single Cell Type RNA - Theca cells [nTPM]":"101.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.8","Single Cell Type RNA - Urothelial cells [nTPM]":"24.1"},{"Gene":"STAT1","Gene synonym":["ISGF-3","STAT91"],"Ensembl":"ENSG00000115415","Gene description":"Signal transducer and activator of transcription 1","Uniprot":["P42224"],"Chromosome":"2","Position":"190908460-191020960","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Antiviral defense","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+":"533.6","BJ hTERT+ SV40 Large T+ RasG12V":"595.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000931","HPA000982","CAB004049"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"92000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 58: T-cells - T-cell receptor","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004049":"AB_2197984","HPA000931":"AB_1080100","HPA000982":"AB_1080099"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.23e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"41.2","Tissue RNA - adrenal gland [nTPM]":"35.6","Tissue RNA - amygdala [nTPM]":"8.0","Tissue RNA - appendix [nTPM]":"113.3","Tissue RNA - basal ganglia [nTPM]":"7.7","Tissue RNA - bone marrow [nTPM]":"35.1","Tissue RNA - breast [nTPM]":"27.1","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"10.2","Tissue RNA - cervix [nTPM]":"33.9","Tissue RNA - choroid plexus [nTPM]":"5.6","Tissue RNA - colon [nTPM]":"43.4","Tissue RNA - duodenum [nTPM]":"51.3","Tissue RNA - endometrium 1 [nTPM]":"27.5","Tissue RNA - epididymis [nTPM]":"15.1","Tissue RNA - esophagus [nTPM]":"35.8","Tissue RNA - fallopian tube [nTPM]":"25.1","Tissue RNA - gallbladder [nTPM]":"66.6","Tissue RNA - heart muscle [nTPM]":"35.6","Tissue RNA - hippocampal formation [nTPM]":"11.1","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"45.3","Tissue RNA - liver [nTPM]":"66.0","Tissue RNA - lung [nTPM]":"69.1","Tissue RNA - lymph node [nTPM]":"145.6","Tissue RNA - medulla oblongata [nTPM]":"18.8","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"33.0","Tissue RNA - pancreas [nTPM]":"40.7","Tissue RNA - parathyroid gland [nTPM]":"39.0","Tissue RNA - pituitary gland [nTPM]":"23.8","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"13.4","Tissue RNA - prostate [nTPM]":"34.8","Tissue RNA - rectum [nTPM]":"40.6","Tissue RNA - retina [nTPM]":"20.0","Tissue RNA - salivary gland [nTPM]":"107.4","Tissue RNA - seminal vesicle [nTPM]":"24.2","Tissue RNA - skeletal muscle [nTPM]":"29.8","Tissue RNA - skin 1 [nTPM]":"24.9","Tissue RNA - small intestine [nTPM]":"41.8","Tissue RNA - smooth muscle [nTPM]":"47.5","Tissue RNA - spinal cord [nTPM]":"27.3","Tissue RNA - spleen [nTPM]":"114.5","Tissue RNA - stomach 1 [nTPM]":"55.7","Tissue RNA - testis [nTPM]":"31.2","Tissue RNA - thalamus [nTPM]":"17.4","Tissue RNA - thymus [nTPM]":"104.3","Tissue RNA - thyroid gland [nTPM]":"33.4","Tissue RNA - tongue [nTPM]":"29.7","Tissue RNA - tonsil [nTPM]":"59.0","Tissue RNA - urinary bladder [nTPM]":"62.2","Tissue RNA - vagina [nTPM]":"25.1","Tissue RNA - white matter [nTPM]":"13.2","Cell RNA - A-431 [nTPM]":"54.8","Cell RNA - A549 [nTPM]":"58.6","Cell RNA - AF22 [nTPM]":"26.8","Cell RNA - AN3-CA [nTPM]":"41.4","Cell RNA - ASC diff [nTPM]":"105.7","Cell RNA - ASC TERT1 [nTPM]":"158.8","Cell RNA - BEWO [nTPM]":"79.3","Cell RNA - BJ [nTPM]":"82.4","Cell RNA - BJ hTERT+ [nTPM]":"257.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"533.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"595.5","Cell RNA - CACO-2 [nTPM]":"95.1","Cell RNA - CAPAN-2 [nTPM]":"62.8","Cell RNA - Daudi [nTPM]":"21.7","Cell RNA - EFO-21 [nTPM]":"48.1","Cell RNA - fHDF\/TERT166 [nTPM]":"180.8","Cell RNA - GAMG [nTPM]":"173.9","Cell RNA - HaCaT [nTPM]":"45.9","Cell RNA - HAP1 [nTPM]":"29.8","Cell RNA - HBEC3-KT [nTPM]":"62.0","Cell RNA - HBF TERT88 [nTPM]":"108.6","Cell RNA - HDLM-2 [nTPM]":"179.6","Cell RNA - HEK 293 [nTPM]":"24.6","Cell RNA - HEL [nTPM]":"99.0","Cell RNA - HeLa [nTPM]":"43.8","Cell RNA - Hep G2 [nTPM]":"47.3","Cell RNA - HHSteC [nTPM]":"72.2","Cell RNA - HL-60 [nTPM]":"48.4","Cell RNA - HMC-1 [nTPM]":"58.3","Cell RNA - HSkMC [nTPM]":"94.7","Cell RNA - hTCEpi [nTPM]":"36.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"100.4","Cell RNA - hTERT-HME1 [nTPM]":"31.0","Cell RNA - hTERT-RPE1 [nTPM]":"56.5","Cell RNA - HUVEC TERT2 [nTPM]":"63.5","Cell RNA - JURKAT [nTPM]":"38.4","Cell RNA - K-562 [nTPM]":"56.8","Cell RNA - Karpas-707 [nTPM]":"103.9","Cell RNA - LHCN-M2 [nTPM]":"93.6","Cell RNA - MCF7 [nTPM]":"42.5","Cell RNA - MOLT-4 [nTPM]":"38.0","Cell RNA - NB-4 [nTPM]":"41.1","Cell RNA - NTERA-2 [nTPM]":"36.6","Cell RNA - OE19 [nTPM]":"34.2","Cell RNA - PC-3 [nTPM]":"95.3","Cell RNA - REH [nTPM]":"31.4","Cell RNA - RH-30 [nTPM]":"71.4","Cell RNA - RPMI-8226 [nTPM]":"27.9","Cell RNA - RPTEC TERT1 [nTPM]":"58.9","Cell RNA - RT4 [nTPM]":"70.1","Cell RNA - SCLC-21H [nTPM]":"37.9","Cell RNA - SH-SY5Y [nTPM]":"35.0","Cell RNA - SiHa [nTPM]":"100.3","Cell RNA - SK-BR-3 [nTPM]":"35.7","Cell RNA - SK-MEL-30 [nTPM]":"236.5","Cell RNA - SuSa [nTPM]":"37.5","Cell RNA - T-47d [nTPM]":"38.6","Cell RNA - THP-1 [nTPM]":"59.9","Cell RNA - TIME [nTPM]":"56.2","Cell RNA - U-138 MG [nTPM]":"105.1","Cell RNA - U-2 OS [nTPM]":"57.5","Cell RNA - U-2197 [nTPM]":"90.0","Cell RNA - U-251 MG [nTPM]":"51.4","Cell RNA - U-266\/70 [nTPM]":"202.1","Cell RNA - U-266\/84 [nTPM]":"330.7","Cell RNA - U-698 [nTPM]":"21.0","Cell RNA - U-87 MG [nTPM]":"80.8","Cell RNA - U-937 [nTPM]":"40.3","Cell RNA - WM-115 [nTPM]":"47.8","Blood RNA - basophil [nTPM]":"50.0","Blood RNA - classical monocyte [nTPM]":"143.9","Blood RNA - eosinophil [nTPM]":"104.9","Blood RNA - gdT-cell [nTPM]":"51.6","Blood RNA - intermediate monocyte [nTPM]":"191.1","Blood RNA - MAIT T-cell [nTPM]":"71.4","Blood RNA - memory B-cell [nTPM]":"38.3","Blood RNA - memory CD4 T-cell [nTPM]":"129.3","Blood RNA - memory CD8 T-cell [nTPM]":"77.4","Blood RNA - myeloid DC [nTPM]":"61.4","Blood RNA - naive B-cell [nTPM]":"31.7","Blood RNA - naive CD4 T-cell [nTPM]":"128.2","Blood RNA - naive CD8 T-cell [nTPM]":"94.2","Blood RNA - neutrophil [nTPM]":"203.9","Blood RNA - NK-cell [nTPM]":"77.3","Blood RNA - non-classical monocyte [nTPM]":"117.3","Blood RNA - plasmacytoid DC [nTPM]":"28.9","Blood RNA - T-reg [nTPM]":"227.8","Blood RNA - total PBMC [nTPM]":"210.2","Brain RNA - amygdala [nTPM]":"8.0","Brain RNA - basal ganglia [nTPM]":"7.7","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"10.2","Brain RNA - hippocampal formation [nTPM]":"11.1","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"18.8","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"13.4","Brain RNA - spinal cord [nTPM]":"27.3","Brain RNA - thalamus [nTPM]":"17.4","Brain RNA - white matter [nTPM]":"13.2","Single Cell Type RNA - Adipocytes [nTPM]":"46.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.3","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"48.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"13.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"40.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.6","Single Cell Type RNA - dendritic cells [nTPM]":"48.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"47.5","Single Cell Type RNA - Early spermatids [nTPM]":"18.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.9","Single Cell Type RNA - Endothelial cells [nTPM]":"42.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"15.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"53.9","Single Cell Type RNA - Fibroblasts [nTPM]":"44.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"51.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.3","Single Cell Type RNA - granulocytes [nTPM]":"51.4","Single Cell Type RNA - Granulosa cells [nTPM]":"38.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"54.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"92.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.7","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"72.0","Single Cell Type RNA - Langerhans cells [nTPM]":"26.2","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"21.8","Single Cell Type RNA - Macrophages [nTPM]":"96.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"107.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.7","Single Cell Type RNA - NK-cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"36.0","Single Cell Type RNA - Paneth cells [nTPM]":"21.7","Single Cell Type RNA - Peritubular cells [nTPM]":"29.7","Single Cell Type RNA - Plasma cells [nTPM]":"69.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"44.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"47.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.1","Single Cell Type RNA - Spermatocytes [nTPM]":"25.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - T-cells [nTPM]":"78.1","Single Cell Type RNA - Theca cells [nTPM]":"37.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.2","Single Cell Type RNA - Urothelial cells [nTPM]":"26.9"},{"Gene":"STAT3","Gene synonym":["APRF"],"Ensembl":"ENSG00000168610","Gene description":"Signal transducer and activator of transcription 3","Uniprot":["P40763"],"Chromosome":"17","Position":"42313324-42388540","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001671","CAB003859","HPA058603","CAB068241","CAB068242"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003859":"AB_347629","CAB068241":"AB_2665663","CAB068242":"AB_2665662","HPA001671":"AB_1080102","HPA058603":"AB_2683772"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Tissue RNA - adipose tissue [nTPM]":"105.6","Tissue RNA - adrenal gland [nTPM]":"68.1","Tissue RNA - amygdala [nTPM]":"32.4","Tissue RNA - appendix [nTPM]":"78.5","Tissue RNA - basal ganglia [nTPM]":"34.5","Tissue RNA - bone marrow [nTPM]":"63.2","Tissue RNA - breast [nTPM]":"84.4","Tissue RNA - cerebellum [nTPM]":"38.7","Tissue RNA - cerebral cortex [nTPM]":"30.2","Tissue RNA - cervix [nTPM]":"62.6","Tissue RNA - choroid plexus [nTPM]":"32.4","Tissue RNA - colon [nTPM]":"76.9","Tissue RNA - duodenum [nTPM]":"45.9","Tissue RNA - endometrium 1 [nTPM]":"71.6","Tissue RNA - epididymis [nTPM]":"28.2","Tissue RNA - esophagus [nTPM]":"81.6","Tissue RNA - fallopian tube [nTPM]":"74.0","Tissue RNA - gallbladder [nTPM]":"71.7","Tissue RNA - heart muscle [nTPM]":"101.2","Tissue RNA - hippocampal formation [nTPM]":"28.6","Tissue RNA - hypothalamus [nTPM]":"44.6","Tissue RNA - kidney [nTPM]":"77.2","Tissue RNA - liver [nTPM]":"143.1","Tissue RNA - lung [nTPM]":"106.0","Tissue RNA - lymph node [nTPM]":"55.3","Tissue RNA - medulla oblongata [nTPM]":"48.4","Tissue RNA - midbrain [nTPM]":"40.7","Tissue RNA - ovary [nTPM]":"65.4","Tissue RNA - pancreas [nTPM]":"67.3","Tissue RNA - parathyroid gland [nTPM]":"35.3","Tissue RNA - pituitary gland [nTPM]":"53.3","Tissue RNA - placenta [nTPM]":"55.6","Tissue RNA - pons [nTPM]":"43.4","Tissue RNA - prostate [nTPM]":"62.9","Tissue RNA - rectum [nTPM]":"46.5","Tissue RNA - retina [nTPM]":"29.9","Tissue RNA - salivary gland [nTPM]":"63.5","Tissue RNA - seminal vesicle [nTPM]":"48.2","Tissue RNA - skeletal muscle [nTPM]":"123.9","Tissue RNA - skin 1 [nTPM]":"66.8","Tissue RNA - small intestine [nTPM]":"68.1","Tissue RNA - smooth muscle [nTPM]":"72.1","Tissue RNA - spinal cord [nTPM]":"43.9","Tissue RNA - spleen [nTPM]":"68.0","Tissue RNA - stomach 1 [nTPM]":"62.3","Tissue RNA - testis [nTPM]":"24.6","Tissue RNA - thalamus [nTPM]":"43.0","Tissue RNA - thymus [nTPM]":"50.5","Tissue RNA - thyroid gland [nTPM]":"61.9","Tissue RNA - tongue [nTPM]":"92.1","Tissue RNA - tonsil [nTPM]":"65.2","Tissue RNA - urinary bladder [nTPM]":"88.6","Tissue RNA - vagina [nTPM]":"64.3","Tissue RNA - white matter [nTPM]":"43.1","Cell RNA - A-431 [nTPM]":"61.5","Cell RNA - A549 [nTPM]":"116.0","Cell RNA - AF22 [nTPM]":"47.4","Cell RNA - AN3-CA [nTPM]":"48.2","Cell RNA - ASC diff [nTPM]":"103.7","Cell RNA - ASC TERT1 [nTPM]":"97.6","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"66.5","Cell RNA - BJ hTERT+ [nTPM]":"89.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.3","Cell RNA - CACO-2 [nTPM]":"30.3","Cell RNA - CAPAN-2 [nTPM]":"55.8","Cell RNA - Daudi [nTPM]":"18.5","Cell RNA - EFO-21 [nTPM]":"68.2","Cell RNA - fHDF\/TERT166 [nTPM]":"71.2","Cell RNA - GAMG [nTPM]":"90.3","Cell RNA - HaCaT [nTPM]":"89.2","Cell RNA - HAP1 [nTPM]":"45.8","Cell RNA - HBEC3-KT [nTPM]":"72.6","Cell RNA - HBF TERT88 [nTPM]":"47.7","Cell RNA - HDLM-2 [nTPM]":"160.6","Cell RNA - HEK 293 [nTPM]":"31.4","Cell RNA - HEL [nTPM]":"131.2","Cell RNA - HeLa [nTPM]":"60.4","Cell RNA - Hep G2 [nTPM]":"62.4","Cell RNA - HHSteC [nTPM]":"77.3","Cell RNA - HL-60 [nTPM]":"31.8","Cell RNA - HMC-1 [nTPM]":"79.0","Cell RNA - HSkMC [nTPM]":"152.1","Cell RNA - hTCEpi [nTPM]":"69.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.4","Cell RNA - hTERT-HME1 [nTPM]":"68.9","Cell RNA - hTERT-RPE1 [nTPM]":"62.2","Cell RNA - HUVEC TERT2 [nTPM]":"81.1","Cell RNA - JURKAT [nTPM]":"33.4","Cell RNA - K-562 [nTPM]":"80.1","Cell RNA - Karpas-707 [nTPM]":"56.4","Cell RNA - LHCN-M2 [nTPM]":"40.1","Cell RNA - MCF7 [nTPM]":"43.8","Cell RNA - MOLT-4 [nTPM]":"118.7","Cell RNA - NB-4 [nTPM]":"31.3","Cell RNA - NTERA-2 [nTPM]":"28.5","Cell RNA - OE19 [nTPM]":"63.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"26.6","Cell RNA - RH-30 [nTPM]":"133.8","Cell RNA - RPMI-8226 [nTPM]":"28.1","Cell RNA - RPTEC TERT1 [nTPM]":"91.3","Cell RNA - RT4 [nTPM]":"77.2","Cell RNA - SCLC-21H [nTPM]":"45.2","Cell RNA - SH-SY5Y [nTPM]":"29.8","Cell RNA - SiHa [nTPM]":"81.4","Cell RNA - SK-BR-3 [nTPM]":"184.9","Cell RNA - SK-MEL-30 [nTPM]":"29.2","Cell RNA - SuSa [nTPM]":"57.2","Cell RNA - T-47d [nTPM]":"100.5","Cell RNA - THP-1 [nTPM]":"49.1","Cell RNA - TIME [nTPM]":"68.7","Cell RNA - U-138 MG [nTPM]":"88.9","Cell RNA - U-2 OS [nTPM]":"44.9","Cell RNA - U-2197 [nTPM]":"54.8","Cell RNA - U-251 MG [nTPM]":"56.5","Cell RNA - U-266\/70 [nTPM]":"82.9","Cell RNA - U-266\/84 [nTPM]":"75.3","Cell RNA - U-698 [nTPM]":"16.4","Cell RNA - U-87 MG [nTPM]":"56.1","Cell RNA - U-937 [nTPM]":"32.8","Cell RNA - WM-115 [nTPM]":"41.6","Blood RNA - basophil [nTPM]":"121.1","Blood RNA - classical monocyte [nTPM]":"78.4","Blood RNA - eosinophil [nTPM]":"100.0","Blood RNA - gdT-cell [nTPM]":"79.5","Blood RNA - intermediate monocyte [nTPM]":"79.9","Blood RNA - MAIT T-cell [nTPM]":"64.4","Blood RNA - memory B-cell [nTPM]":"40.2","Blood RNA - memory CD4 T-cell [nTPM]":"57.5","Blood RNA - memory CD8 T-cell [nTPM]":"62.6","Blood RNA - myeloid DC [nTPM]":"54.3","Blood RNA - naive B-cell [nTPM]":"36.6","Blood RNA - naive CD4 T-cell [nTPM]":"58.7","Blood RNA - naive CD8 T-cell [nTPM]":"56.5","Blood RNA - neutrophil [nTPM]":"262.6","Blood RNA - NK-cell [nTPM]":"58.3","Blood RNA - non-classical monocyte [nTPM]":"80.8","Blood RNA - plasmacytoid DC [nTPM]":"29.3","Blood RNA - T-reg [nTPM]":"47.9","Blood RNA - total PBMC [nTPM]":"124.5","Brain RNA - amygdala [nTPM]":"32.4","Brain RNA - basal ganglia [nTPM]":"34.5","Brain RNA - cerebellum [nTPM]":"38.7","Brain RNA - cerebral cortex [nTPM]":"30.2","Brain RNA - hippocampal formation [nTPM]":"28.6","Brain RNA - hypothalamus [nTPM]":"44.6","Brain RNA - medulla oblongata [nTPM]":"48.4","Brain RNA - midbrain [nTPM]":"40.7","Brain RNA - pons [nTPM]":"43.4","Brain RNA - spinal cord [nTPM]":"43.9","Brain RNA - thalamus [nTPM]":"43.0","Brain RNA - white matter [nTPM]":"43.1","Single Cell Type RNA - Adipocytes [nTPM]":"216.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"93.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"173.7","Single Cell Type RNA - Astrocytes [nTPM]":"46.0","Single Cell Type RNA - B-cells [nTPM]":"111.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"129.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"76.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"138.3","Single Cell Type RNA - Bipolar cells [nTPM]":"92.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"147.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"113.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"103.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"134.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"281.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - dendritic cells [nTPM]":"115.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"148.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"83.2","Single Cell Type RNA - Early spermatids [nTPM]":"33.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"129.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"187.0","Single Cell Type RNA - Endothelial cells [nTPM]":"164.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"124.0","Single Cell Type RNA - Erythroid cells [nTPM]":"54.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"96.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.2","Single Cell Type RNA - Fibroblasts [nTPM]":"154.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"109.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"153.9","Single Cell Type RNA - granulocytes [nTPM]":"142.0","Single Cell Type RNA - Granulosa cells [nTPM]":"86.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"115.3","Single Cell Type RNA - Hepatocytes [nTPM]":"115.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"97.8","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"71.0","Single Cell Type RNA - Langerhans cells [nTPM]":"121.7","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"71.7","Single Cell Type RNA - Macrophages [nTPM]":"111.7","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"94.1","Single Cell Type RNA - Muller glia cells [nTPM]":"131.3","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"82.9","Single Cell Type RNA - Paneth cells [nTPM]":"94.5","Single Cell Type RNA - Peritubular cells [nTPM]":"60.9","Single Cell Type RNA - Plasma cells [nTPM]":"104.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"147.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"206.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"88.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"406.7","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"189.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"169.7","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"15.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"93.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"160.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"170.2","Single Cell Type RNA - Theca cells [nTPM]":"102.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"117.5","Single Cell Type RNA - Urothelial cells [nTPM]":"90.6"},{"Gene":"STAT5B","Gene synonym":[],"Ensembl":"ENSG00000173757","Gene description":"Signal transducer and activator of transcription 5B","Uniprot":["P51692"],"Chromosome":"17","Position":"42199177-42276707","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"100.5","Late spermatids":"188.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"121.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004298","CAB005418","HPA042128","HPA049883","HPA051156"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004298":"AB_2197067","CAB005418":"AB_632445","HPA042128":"AB_2677864","HPA049883":"AB_2680931","HPA051156":"AB_2681366"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.37e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"45.9","Tissue RNA - adrenal gland [nTPM]":"45.7","Tissue RNA - amygdala [nTPM]":"26.4","Tissue RNA - appendix [nTPM]":"35.1","Tissue RNA - basal ganglia [nTPM]":"26.5","Tissue RNA - bone marrow [nTPM]":"42.4","Tissue RNA - breast [nTPM]":"36.7","Tissue RNA - cerebellum [nTPM]":"33.4","Tissue RNA - cerebral cortex [nTPM]":"29.0","Tissue RNA - cervix [nTPM]":"43.6","Tissue RNA - choroid plexus [nTPM]":"24.6","Tissue RNA - colon [nTPM]":"45.3","Tissue RNA - duodenum [nTPM]":"14.8","Tissue RNA - endometrium 1 [nTPM]":"59.1","Tissue RNA - epididymis [nTPM]":"19.3","Tissue RNA - esophagus [nTPM]":"19.2","Tissue RNA - fallopian tube [nTPM]":"50.8","Tissue RNA - gallbladder [nTPM]":"23.6","Tissue RNA - heart muscle [nTPM]":"24.5","Tissue RNA - hippocampal formation [nTPM]":"23.5","Tissue RNA - hypothalamus [nTPM]":"42.9","Tissue RNA - kidney [nTPM]":"24.3","Tissue RNA - liver [nTPM]":"24.4","Tissue RNA - lung [nTPM]":"32.5","Tissue RNA - lymph node [nTPM]":"43.6","Tissue RNA - medulla oblongata [nTPM]":"32.8","Tissue RNA - midbrain [nTPM]":"33.9","Tissue RNA - ovary [nTPM]":"55.9","Tissue RNA - pancreas [nTPM]":"22.8","Tissue RNA - parathyroid gland [nTPM]":"21.1","Tissue RNA - pituitary gland [nTPM]":"40.8","Tissue RNA - placenta [nTPM]":"31.5","Tissue RNA - pons [nTPM]":"32.9","Tissue RNA - prostate [nTPM]":"29.2","Tissue RNA - rectum [nTPM]":"17.0","Tissue RNA - retina [nTPM]":"18.7","Tissue RNA - salivary gland [nTPM]":"22.8","Tissue RNA - seminal vesicle [nTPM]":"34.2","Tissue RNA - skeletal muscle [nTPM]":"73.3","Tissue RNA - skin 1 [nTPM]":"25.3","Tissue RNA - small intestine [nTPM]":"30.7","Tissue RNA - smooth muscle [nTPM]":"42.7","Tissue RNA - spinal cord [nTPM]":"27.4","Tissue RNA - spleen [nTPM]":"42.3","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"23.5","Tissue RNA - thalamus [nTPM]":"49.9","Tissue RNA - thymus [nTPM]":"37.6","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"46.5","Tissue RNA - tonsil [nTPM]":"34.7","Tissue RNA - urinary bladder [nTPM]":"43.4","Tissue RNA - vagina [nTPM]":"31.5","Tissue RNA - white matter [nTPM]":"26.1","Cell RNA - A-431 [nTPM]":"15.0","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"33.3","Cell RNA - AN3-CA [nTPM]":"9.0","Cell RNA - ASC diff [nTPM]":"40.6","Cell RNA - ASC TERT1 [nTPM]":"20.4","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"15.0","Cell RNA - BJ hTERT+ [nTPM]":"26.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.2","Cell RNA - CACO-2 [nTPM]":"10.1","Cell RNA - CAPAN-2 [nTPM]":"12.3","Cell RNA - Daudi [nTPM]":"48.1","Cell RNA - EFO-21 [nTPM]":"21.8","Cell RNA - fHDF\/TERT166 [nTPM]":"17.2","Cell RNA - GAMG [nTPM]":"41.3","Cell RNA - HaCaT [nTPM]":"18.7","Cell RNA - HAP1 [nTPM]":"19.9","Cell RNA - HBEC3-KT [nTPM]":"13.0","Cell RNA - HBF TERT88 [nTPM]":"16.6","Cell RNA - HDLM-2 [nTPM]":"121.8","Cell RNA - HEK 293 [nTPM]":"23.0","Cell RNA - HEL [nTPM]":"47.1","Cell RNA - HeLa [nTPM]":"44.5","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"22.3","Cell RNA - HL-60 [nTPM]":"20.9","Cell RNA - HMC-1 [nTPM]":"72.7","Cell RNA - HSkMC [nTPM]":"25.1","Cell RNA - hTCEpi [nTPM]":"19.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.9","Cell RNA - hTERT-HME1 [nTPM]":"19.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"33.6","Cell RNA - JURKAT [nTPM]":"31.9","Cell RNA - K-562 [nTPM]":"86.5","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"8.8","Cell RNA - MCF7 [nTPM]":"14.6","Cell RNA - MOLT-4 [nTPM]":"99.2","Cell RNA - NB-4 [nTPM]":"54.9","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"34.3","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"42.0","Cell RNA - RH-30 [nTPM]":"20.9","Cell RNA - RPMI-8226 [nTPM]":"16.8","Cell RNA - RPTEC TERT1 [nTPM]":"13.3","Cell RNA - RT4 [nTPM]":"23.5","Cell RNA - SCLC-21H [nTPM]":"24.5","Cell RNA - SH-SY5Y [nTPM]":"14.4","Cell RNA - SiHa [nTPM]":"27.3","Cell RNA - SK-BR-3 [nTPM]":"34.4","Cell RNA - SK-MEL-30 [nTPM]":"21.2","Cell RNA - SuSa [nTPM]":"7.4","Cell RNA - T-47d [nTPM]":"24.3","Cell RNA - THP-1 [nTPM]":"24.3","Cell RNA - TIME [nTPM]":"26.0","Cell RNA - U-138 MG [nTPM]":"29.2","Cell RNA - U-2 OS [nTPM]":"10.2","Cell RNA - U-2197 [nTPM]":"15.2","Cell RNA - U-251 MG [nTPM]":"21.2","Cell RNA - U-266\/70 [nTPM]":"19.8","Cell RNA - U-266\/84 [nTPM]":"9.8","Cell RNA - U-698 [nTPM]":"23.9","Cell RNA - U-87 MG [nTPM]":"11.6","Cell RNA - U-937 [nTPM]":"21.7","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"11.5","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"5.9","Blood RNA - gdT-cell [nTPM]":"6.6","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"7.1","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.6","Blood RNA - myeloid DC [nTPM]":"2.9","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"6.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"22.5","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"8.4","Blood RNA - total PBMC [nTPM]":"4.7","Brain RNA - amygdala [nTPM]":"26.4","Brain RNA - basal ganglia [nTPM]":"26.5","Brain RNA - cerebellum [nTPM]":"33.4","Brain RNA - cerebral cortex [nTPM]":"29.0","Brain RNA - hippocampal formation [nTPM]":"23.5","Brain RNA - hypothalamus [nTPM]":"42.9","Brain RNA - medulla oblongata [nTPM]":"32.8","Brain RNA - midbrain [nTPM]":"33.9","Brain RNA - pons [nTPM]":"32.9","Brain RNA - spinal cord [nTPM]":"27.4","Brain RNA - thalamus [nTPM]":"49.9","Brain RNA - white matter [nTPM]":"26.1","Single Cell Type RNA - Adipocytes [nTPM]":"30.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.5","Single Cell Type RNA - Astrocytes [nTPM]":"41.8","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"21.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.0","Single Cell Type RNA - dendritic cells [nTPM]":"31.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.2","Single Cell Type RNA - Early spermatids [nTPM]":"100.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.4","Single Cell Type RNA - Endothelial cells [nTPM]":"26.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.0","Single Cell Type RNA - granulocytes [nTPM]":"16.4","Single Cell Type RNA - Granulosa cells [nTPM]":"16.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"11.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.1","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.3","Single Cell Type RNA - Langerhans cells [nTPM]":"17.1","Single Cell Type RNA - Late spermatids [nTPM]":"188.5","Single Cell Type RNA - Leydig cells [nTPM]":"47.2","Single Cell Type RNA - Macrophages [nTPM]":"16.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"23.7","Single Cell Type RNA - Muller glia cells [nTPM]":"9.5","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"69.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.2","Single Cell Type RNA - Peritubular cells [nTPM]":"74.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - T-cells [nTPM]":"34.4","Single Cell Type RNA - Theca cells [nTPM]":"15.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"STIM1","Gene synonym":["D11S4896E","GOK"],"Ensembl":"ENSG00000167323","Gene description":"Stromal interaction molecule 1","Uniprot":["Q13586"],"Chromosome":"11","Position":"3854527-4093210","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"77.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011088","HPA012123","CAB037128","CAB037288"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1900000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB037128":"AB_1079007","CAB037288":"AB_1079008","HPA011088":"AB_1849884","HPA012123":"AB_1849882"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Tissue RNA - adipose tissue [nTPM]":"40.6","Tissue RNA - adrenal gland [nTPM]":"18.4","Tissue RNA - amygdala [nTPM]":"32.9","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"31.5","Tissue RNA - bone marrow [nTPM]":"46.4","Tissue RNA - breast [nTPM]":"33.1","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"34.5","Tissue RNA - cervix [nTPM]":"40.4","Tissue RNA - choroid plexus [nTPM]":"30.5","Tissue RNA - colon [nTPM]":"33.7","Tissue RNA - duodenum [nTPM]":"18.1","Tissue RNA - endometrium 1 [nTPM]":"39.3","Tissue RNA - epididymis [nTPM]":"18.2","Tissue RNA - esophagus [nTPM]":"65.6","Tissue RNA - fallopian tube [nTPM]":"39.0","Tissue RNA - gallbladder [nTPM]":"25.1","Tissue RNA - heart muscle [nTPM]":"24.0","Tissue RNA - hippocampal formation [nTPM]":"30.5","Tissue RNA - hypothalamus [nTPM]":"23.1","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"38.0","Tissue RNA - lung [nTPM]":"26.8","Tissue RNA - lymph node [nTPM]":"29.8","Tissue RNA - medulla oblongata [nTPM]":"17.4","Tissue RNA - midbrain [nTPM]":"22.9","Tissue RNA - ovary [nTPM]":"41.2","Tissue RNA - pancreas [nTPM]":"30.1","Tissue RNA - parathyroid gland [nTPM]":"43.7","Tissue RNA - pituitary gland [nTPM]":"18.0","Tissue RNA - placenta [nTPM]":"17.5","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"26.0","Tissue RNA - rectum [nTPM]":"24.6","Tissue RNA - retina [nTPM]":"11.4","Tissue RNA - salivary gland [nTPM]":"61.1","Tissue RNA - seminal vesicle [nTPM]":"24.3","Tissue RNA - skeletal muscle [nTPM]":"111.9","Tissue RNA - skin 1 [nTPM]":"47.1","Tissue RNA - small intestine [nTPM]":"31.3","Tissue RNA - smooth muscle [nTPM]":"34.3","Tissue RNA - spinal cord [nTPM]":"18.6","Tissue RNA - spleen [nTPM]":"31.5","Tissue RNA - stomach 1 [nTPM]":"32.2","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"26.9","Tissue RNA - thymus [nTPM]":"68.6","Tissue RNA - thyroid gland [nTPM]":"40.9","Tissue RNA - tongue [nTPM]":"49.7","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"32.2","Tissue RNA - vagina [nTPM]":"40.4","Tissue RNA - white matter [nTPM]":"22.4","Cell RNA - A-431 [nTPM]":"42.4","Cell RNA - A549 [nTPM]":"48.5","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"23.5","Cell RNA - ASC diff [nTPM]":"60.9","Cell RNA - ASC TERT1 [nTPM]":"55.4","Cell RNA - BEWO [nTPM]":"22.2","Cell RNA - BJ [nTPM]":"31.1","Cell RNA - BJ hTERT+ [nTPM]":"31.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.5","Cell RNA - CACO-2 [nTPM]":"24.3","Cell RNA - CAPAN-2 [nTPM]":"13.8","Cell RNA - Daudi [nTPM]":"44.7","Cell RNA - EFO-21 [nTPM]":"35.4","Cell RNA - fHDF\/TERT166 [nTPM]":"46.2","Cell RNA - GAMG [nTPM]":"50.9","Cell RNA - HaCaT [nTPM]":"74.3","Cell RNA - HAP1 [nTPM]":"20.1","Cell RNA - HBEC3-KT [nTPM]":"21.5","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"36.7","Cell RNA - HEK 293 [nTPM]":"30.5","Cell RNA - HEL [nTPM]":"70.1","Cell RNA - HeLa [nTPM]":"19.2","Cell RNA - Hep G2 [nTPM]":"36.0","Cell RNA - HHSteC [nTPM]":"53.0","Cell RNA - HL-60 [nTPM]":"58.9","Cell RNA - HMC-1 [nTPM]":"40.1","Cell RNA - HSkMC [nTPM]":"56.8","Cell RNA - hTCEpi [nTPM]":"53.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.0","Cell RNA - hTERT-HME1 [nTPM]":"90.7","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"31.7","Cell RNA - JURKAT [nTPM]":"59.6","Cell RNA - K-562 [nTPM]":"44.2","Cell RNA - Karpas-707 [nTPM]":"80.1","Cell RNA - LHCN-M2 [nTPM]":"24.7","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"55.8","Cell RNA - NB-4 [nTPM]":"20.7","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"23.3","Cell RNA - PC-3 [nTPM]":"18.1","Cell RNA - REH [nTPM]":"13.8","Cell RNA - RH-30 [nTPM]":"22.1","Cell RNA - RPMI-8226 [nTPM]":"41.7","Cell RNA - RPTEC TERT1 [nTPM]":"38.2","Cell RNA - RT4 [nTPM]":"23.7","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"14.2","Cell RNA - SiHa [nTPM]":"51.2","Cell RNA - SK-BR-3 [nTPM]":"33.5","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"22.5","Cell RNA - T-47d [nTPM]":"12.7","Cell RNA - THP-1 [nTPM]":"32.4","Cell RNA - TIME [nTPM]":"34.0","Cell RNA - U-138 MG [nTPM]":"40.2","Cell RNA - U-2 OS [nTPM]":"13.8","Cell RNA - U-2197 [nTPM]":"42.2","Cell RNA - U-251 MG [nTPM]":"25.1","Cell RNA - U-266\/70 [nTPM]":"88.0","Cell RNA - U-266\/84 [nTPM]":"71.9","Cell RNA - U-698 [nTPM]":"22.5","Cell RNA - U-87 MG [nTPM]":"33.4","Cell RNA - U-937 [nTPM]":"24.0","Cell RNA - WM-115 [nTPM]":"26.0","Blood RNA - basophil [nTPM]":"16.6","Blood RNA - classical monocyte [nTPM]":"11.2","Blood RNA - eosinophil [nTPM]":"20.0","Blood RNA - gdT-cell [nTPM]":"17.8","Blood RNA - intermediate monocyte [nTPM]":"14.8","Blood RNA - MAIT T-cell [nTPM]":"14.5","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"13.1","Blood RNA - memory CD8 T-cell [nTPM]":"19.5","Blood RNA - myeloid DC [nTPM]":"9.6","Blood RNA - naive B-cell [nTPM]":"11.4","Blood RNA - naive CD4 T-cell [nTPM]":"14.8","Blood RNA - naive CD8 T-cell [nTPM]":"13.3","Blood RNA - neutrophil [nTPM]":"16.7","Blood RNA - NK-cell [nTPM]":"20.8","Blood RNA - non-classical monocyte [nTPM]":"25.5","Blood RNA - plasmacytoid DC [nTPM]":"8.3","Blood RNA - T-reg [nTPM]":"14.7","Blood RNA - total PBMC [nTPM]":"17.1","Brain RNA - amygdala [nTPM]":"32.9","Brain RNA - basal ganglia [nTPM]":"31.5","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"34.5","Brain RNA - hippocampal formation [nTPM]":"30.5","Brain RNA - hypothalamus [nTPM]":"23.1","Brain RNA - medulla oblongata [nTPM]":"17.4","Brain RNA - midbrain [nTPM]":"22.9","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"18.6","Brain RNA - thalamus [nTPM]":"26.9","Brain RNA - white matter [nTPM]":"22.4","Single Cell Type RNA - Adipocytes [nTPM]":"20.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"53.8","Single Cell Type RNA - B-cells [nTPM]":"22.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.3","Single Cell Type RNA - dendritic cells [nTPM]":"35.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.5","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"63.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.5","Single Cell Type RNA - Fibroblasts [nTPM]":"20.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.0","Single Cell Type RNA - granulocytes [nTPM]":"29.8","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"32.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.7","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"56.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"22.2","Single Cell Type RNA - Langerhans cells [nTPM]":"15.2","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"18.7","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"77.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.3","Single Cell Type RNA - Paneth cells [nTPM]":"6.7","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"14.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.4","Single Cell Type RNA - Spermatocytes [nTPM]":"21.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - T-cells [nTPM]":"28.5","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"STX11","Gene synonym":[],"Ensembl":"ENSG00000135604","Gene description":"Syntaxin 11","Uniprot":["O75558"],"Chromosome":"6","Position":"144150517-144191939","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Familial hemophagocytic lymphohistiocytosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"25.1","bone marrow":"56.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"85.0","granulocytes":"90.3","Langerhans cells":"271.6","Macrophages":"158.0","monocytes":"85.5","Suprabasal keratinocytes":"154.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"22.6","classical monocyte":"68.4","eosinophil":"43.5","intermediate monocyte":"81.1","myeloid DC":"25.4","neutrophil":"81.7","non-classical monocyte":"87.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"8","RNA blood lineage specific nTPM":{"dendritic cells":"25.4","granulocytes":"81.7","monocytes":"87.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"17.2","Karpas-707":"10.1","RH-30":"6.9","TIME":"8.3","U-266\/70":"11.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007992"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007992":"AB_1857620"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.1","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"56.5","Tissue RNA - breast [nTPM]":"14.5","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"2.8","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"5.1","Tissue RNA - fallopian tube [nTPM]":"2.6","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"3.1","Tissue RNA - lung [nTPM]":"21.3","Tissue RNA - lymph node [nTPM]":"5.5","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.6","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"3.3","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"7.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"3.5","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"1.1","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"3.9","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.6","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"17.2","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"4.3","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"6.9","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"1.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"3.8","Cell RNA - TIME [nTPM]":"8.3","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"11.6","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"2.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"22.6","Blood RNA - classical monocyte [nTPM]":"68.4","Blood RNA - eosinophil [nTPM]":"43.5","Blood RNA - gdT-cell [nTPM]":"6.0","Blood RNA - intermediate monocyte [nTPM]":"81.1","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.7","Blood RNA - memory CD8 T-cell [nTPM]":"5.1","Blood RNA - myeloid DC [nTPM]":"25.4","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"81.7","Blood RNA - NK-cell [nTPM]":"3.2","Blood RNA - non-classical monocyte [nTPM]":"87.0","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"43.9","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.1","Single Cell Type RNA - Adipocytes [nTPM]":"41.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"16.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"6.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"38.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"23.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"11.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.0","Single Cell Type RNA - granulocytes [nTPM]":"90.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"73.7","Single Cell Type RNA - Langerhans cells [nTPM]":"271.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"158.0","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"85.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"63.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"46.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"154.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.0","Single Cell Type RNA - T-cells [nTPM]":"36.6","Single Cell Type RNA - Theca cells [nTPM]":"3.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"33.3"},{"Gene":"TAP1","Gene synonym":["ABCB2","D6S114E","PSF1","RING4"],"Ensembl":"ENSG00000168394","Gene description":"Transporter 1, ATP binding cassette subfamily B member","Uniprot":["Q03518"],"Chromosome":"6","Position":"32845209-32853816","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Peptide transport","Protein transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"126.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009516","HPA072354"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Centriolar satellite"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum","Centriolar satellite"],"Subcellular additional location":null,"Antibody RRID":{"CAB009516":"AB_2303048","HPA072354":"AB_2686513"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.01e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.07e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"28.4","Tissue RNA - adrenal gland [nTPM]":"24.9","Tissue RNA - amygdala [nTPM]":"16.1","Tissue RNA - appendix [nTPM]":"50.1","Tissue RNA - basal ganglia [nTPM]":"16.2","Tissue RNA - bone marrow [nTPM]":"13.7","Tissue RNA - breast [nTPM]":"20.7","Tissue RNA - cerebellum [nTPM]":"15.8","Tissue RNA - cerebral cortex [nTPM]":"20.3","Tissue RNA - cervix [nTPM]":"21.6","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"30.3","Tissue RNA - duodenum [nTPM]":"36.0","Tissue RNA - endometrium 1 [nTPM]":"20.5","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"31.6","Tissue RNA - fallopian tube [nTPM]":"17.8","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"25.4","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"16.2","Tissue RNA - kidney [nTPM]":"21.8","Tissue RNA - liver [nTPM]":"19.3","Tissue RNA - lung [nTPM]":"52.7","Tissue RNA - lymph node [nTPM]":"50.0","Tissue RNA - medulla oblongata [nTPM]":"24.0","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"12.1","Tissue RNA - pancreas [nTPM]":"14.5","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"21.2","Tissue RNA - prostate [nTPM]":"21.9","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"16.3","Tissue RNA - skin 1 [nTPM]":"51.2","Tissue RNA - small intestine [nTPM]":"42.6","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"18.6","Tissue RNA - spleen [nTPM]":"73.0","Tissue RNA - stomach 1 [nTPM]":"33.4","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"19.4","Tissue RNA - thymus [nTPM]":"25.5","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"7.4","Tissue RNA - tonsil [nTPM]":"21.3","Tissue RNA - urinary bladder [nTPM]":"23.9","Tissue RNA - vagina [nTPM]":"24.4","Tissue RNA - white matter [nTPM]":"17.4","Cell RNA - A-431 [nTPM]":"22.9","Cell RNA - A549 [nTPM]":"13.7","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"16.1","Cell RNA - ASC diff [nTPM]":"8.8","Cell RNA - ASC TERT1 [nTPM]":"11.4","Cell RNA - BEWO [nTPM]":"126.2","Cell RNA - BJ [nTPM]":"8.1","Cell RNA - BJ hTERT+ [nTPM]":"34.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"86.5","Cell RNA - CACO-2 [nTPM]":"2.0","Cell RNA - CAPAN-2 [nTPM]":"27.3","Cell RNA - Daudi [nTPM]":"41.8","Cell RNA - EFO-21 [nTPM]":"25.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.6","Cell RNA - GAMG [nTPM]":"48.9","Cell RNA - HaCaT [nTPM]":"45.8","Cell RNA - HAP1 [nTPM]":"4.5","Cell RNA - HBEC3-KT [nTPM]":"20.6","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"81.0","Cell RNA - HEK 293 [nTPM]":"6.1","Cell RNA - HEL [nTPM]":"26.5","Cell RNA - HeLa [nTPM]":"4.1","Cell RNA - Hep G2 [nTPM]":"10.8","Cell RNA - HHSteC [nTPM]":"42.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"17.5","Cell RNA - HSkMC [nTPM]":"15.0","Cell RNA - hTCEpi [nTPM]":"17.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.1","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"8.6","Cell RNA - HUVEC TERT2 [nTPM]":"15.4","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"55.0","Cell RNA - LHCN-M2 [nTPM]":"10.6","Cell RNA - MCF7 [nTPM]":"10.5","Cell RNA - MOLT-4 [nTPM]":"17.7","Cell RNA - NB-4 [nTPM]":"27.4","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"3.1","Cell RNA - PC-3 [nTPM]":"11.1","Cell RNA - REH [nTPM]":"47.6","Cell RNA - RH-30 [nTPM]":"5.2","Cell RNA - RPMI-8226 [nTPM]":"32.8","Cell RNA - RPTEC TERT1 [nTPM]":"25.0","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"6.7","Cell RNA - SK-BR-3 [nTPM]":"38.0","Cell RNA - SK-MEL-30 [nTPM]":"33.4","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"30.9","Cell RNA - THP-1 [nTPM]":"37.4","Cell RNA - TIME [nTPM]":"9.7","Cell RNA - U-138 MG [nTPM]":"21.5","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"53.1","Cell RNA - U-251 MG [nTPM]":"11.4","Cell RNA - U-266\/70 [nTPM]":"59.9","Cell RNA - U-266\/84 [nTPM]":"82.6","Cell RNA - U-698 [nTPM]":"12.6","Cell RNA - U-87 MG [nTPM]":"16.6","Cell RNA - U-937 [nTPM]":"16.6","Cell RNA - WM-115 [nTPM]":"16.4","Blood RNA - basophil [nTPM]":"176.8","Blood RNA - classical monocyte [nTPM]":"99.5","Blood RNA - eosinophil [nTPM]":"270.1","Blood RNA - gdT-cell [nTPM]":"155.8","Blood RNA - intermediate monocyte [nTPM]":"101.6","Blood RNA - MAIT T-cell [nTPM]":"133.8","Blood RNA - memory B-cell [nTPM]":"137.3","Blood RNA - memory CD4 T-cell [nTPM]":"125.2","Blood RNA - memory CD8 T-cell [nTPM]":"153.7","Blood RNA - myeloid DC [nTPM]":"95.0","Blood RNA - naive B-cell [nTPM]":"107.5","Blood RNA - naive CD4 T-cell [nTPM]":"120.9","Blood RNA - naive CD8 T-cell [nTPM]":"124.6","Blood RNA - neutrophil [nTPM]":"295.6","Blood RNA - NK-cell [nTPM]":"132.9","Blood RNA - non-classical monocyte [nTPM]":"94.6","Blood RNA - plasmacytoid DC [nTPM]":"94.8","Blood RNA - T-reg [nTPM]":"213.8","Blood RNA - total PBMC [nTPM]":"221.2","Brain RNA - amygdala [nTPM]":"16.1","Brain RNA - basal ganglia [nTPM]":"16.2","Brain RNA - cerebellum [nTPM]":"15.8","Brain RNA - cerebral cortex [nTPM]":"20.3","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"16.2","Brain RNA - medulla oblongata [nTPM]":"24.0","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"21.2","Brain RNA - spinal cord [nTPM]":"18.6","Brain RNA - thalamus [nTPM]":"19.4","Brain RNA - white matter [nTPM]":"17.4","Single Cell Type RNA - Adipocytes [nTPM]":"72.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"62.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"74.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"54.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"4.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"33.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"108.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"78.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"81.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.3","Single Cell Type RNA - Endothelial cells [nTPM]":"63.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"12.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"75.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.0","Single Cell Type RNA - Fibroblasts [nTPM]":"26.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"77.9","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.1","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"55.9","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"31.9","Single Cell Type RNA - Langerhans cells [nTPM]":"90.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"43.9","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"115.9","Single Cell Type RNA - Muller glia cells [nTPM]":"25.1","Single Cell Type RNA - NK-cells [nTPM]":"149.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"91.3","Single Cell Type RNA - Paneth cells [nTPM]":"38.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"84.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"84.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"76.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"92.3","Single Cell Type RNA - Theca cells [nTPM]":"18.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.5","Single Cell Type RNA - Urothelial cells [nTPM]":"52.1"},{"Gene":"TAP2","Gene synonym":["ABCB3","D6S217E","PSF2","RING11"],"Ensembl":"ENSG00000204267","Gene description":"Transporter 2, ATP binding cassette subfamily B member","Uniprot":["Q03519"],"Chromosome":"6","Position":"32821833-32838770","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Peptide transport","Protein transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"69.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"61.4","U-251 MG":"52.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001312"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nuclear speckles"],"Antibody RRID":{"HPA001312":"AB_1080206"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.51e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.22e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.1","Tissue RNA - adrenal gland [nTPM]":"11.7","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"8.8","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"16.3","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"14.6","Tissue RNA - duodenum [nTPM]":"10.2","Tissue RNA - endometrium 1 [nTPM]":"13.7","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"26.0","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"14.4","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"11.5","Tissue RNA - lung [nTPM]":"25.7","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"9.2","Tissue RNA - pancreas [nTPM]":"9.0","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"2.5","Tissue RNA - salivary gland [nTPM]":"11.2","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"14.5","Tissue RNA - small intestine [nTPM]":"25.2","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"29.8","Tissue RNA - stomach 1 [nTPM]":"11.4","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"17.2","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"6.1","Cell RNA - ASC TERT1 [nTPM]":"6.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.7","Cell RNA - CACO-2 [nTPM]":"3.9","Cell RNA - CAPAN-2 [nTPM]":"41.0","Cell RNA - Daudi [nTPM]":"36.5","Cell RNA - EFO-21 [nTPM]":"7.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.1","Cell RNA - GAMG [nTPM]":"37.1","Cell RNA - HaCaT [nTPM]":"38.8","Cell RNA - HAP1 [nTPM]":"15.8","Cell RNA - HBEC3-KT [nTPM]":"61.4","Cell RNA - HBF TERT88 [nTPM]":"6.9","Cell RNA - HDLM-2 [nTPM]":"43.8","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"20.3","Cell RNA - HeLa [nTPM]":"11.6","Cell RNA - Hep G2 [nTPM]":"1.3","Cell RNA - HHSteC [nTPM]":"8.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"29.5","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.3","Cell RNA - hTERT-HME1 [nTPM]":"24.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"12.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"20.0","Cell RNA - Karpas-707 [nTPM]":"12.2","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"11.7","Cell RNA - REH [nTPM]":"25.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"12.8","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"1.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"16.0","Cell RNA - SK-BR-3 [nTPM]":"37.3","Cell RNA - SK-MEL-30 [nTPM]":"4.1","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"7.4","Cell RNA - THP-1 [nTPM]":"1.9","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"25.7","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"3.9","Cell RNA - U-251 MG [nTPM]":"52.0","Cell RNA - U-266\/70 [nTPM]":"17.9","Cell RNA - U-266\/84 [nTPM]":"31.4","Cell RNA - U-698 [nTPM]":"33.3","Cell RNA - U-87 MG [nTPM]":"19.5","Cell RNA - U-937 [nTPM]":"25.7","Cell RNA - WM-115 [nTPM]":"10.9","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"3.0","Blood RNA - intermediate monocyte [nTPM]":"3.2","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"3.8","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"48.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"20.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"37.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.4","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"4.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"45.8","Single Cell Type RNA - Fibroblasts [nTPM]":"8.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"8.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"20.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"69.3","Single Cell Type RNA - Muller glia cells [nTPM]":"17.7","Single Cell Type RNA - NK-cells [nTPM]":"47.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.6","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"24.0","Single Cell Type RNA - Theca cells [nTPM]":"20.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.3","Single Cell Type RNA - Urothelial cells [nTPM]":"16.7"},{"Gene":"TAPBP","Gene synonym":["TAPA"],"Ensembl":"ENSG00000231925","Gene description":"TAP binding protein","Uniprot":["O15533"],"Chromosome":"6","Position":"33299694-33314387","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"168.7","Karpas-707":"140.8","U-266\/70":"140.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007066"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA007066":"AB_1857769"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.29e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Tissue RNA - adipose tissue [nTPM]":"47.3","Tissue RNA - adrenal gland [nTPM]":"73.1","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"28.5","Tissue RNA - basal ganglia [nTPM]":"4.8","Tissue RNA - bone marrow [nTPM]":"25.0","Tissue RNA - breast [nTPM]":"43.1","Tissue RNA - cerebellum [nTPM]":"1.9","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"40.1","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"66.7","Tissue RNA - duodenum [nTPM]":"52.3","Tissue RNA - endometrium 1 [nTPM]":"38.2","Tissue RNA - epididymis [nTPM]":"13.3","Tissue RNA - esophagus [nTPM]":"57.3","Tissue RNA - fallopian tube [nTPM]":"43.8","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"63.7","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"67.4","Tissue RNA - liver [nTPM]":"107.5","Tissue RNA - lung [nTPM]":"82.1","Tissue RNA - lymph node [nTPM]":"21.2","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"33.3","Tissue RNA - pancreas [nTPM]":"48.2","Tissue RNA - parathyroid gland [nTPM]":"14.9","Tissue RNA - pituitary gland [nTPM]":"38.8","Tissue RNA - placenta [nTPM]":"18.7","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"64.3","Tissue RNA - rectum [nTPM]":"19.6","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"61.9","Tissue RNA - seminal vesicle [nTPM]":"17.2","Tissue RNA - skeletal muscle [nTPM]":"26.7","Tissue RNA - skin 1 [nTPM]":"54.0","Tissue RNA - small intestine [nTPM]":"81.9","Tissue RNA - smooth muscle [nTPM]":"23.1","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"129.0","Tissue RNA - stomach 1 [nTPM]":"52.1","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"24.4","Tissue RNA - thyroid gland [nTPM]":"59.1","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"36.7","Tissue RNA - urinary bladder [nTPM]":"45.0","Tissue RNA - vagina [nTPM]":"43.4","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"3.3","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"6.3","Cell RNA - AN3-CA [nTPM]":"26.1","Cell RNA - ASC diff [nTPM]":"20.3","Cell RNA - ASC TERT1 [nTPM]":"25.6","Cell RNA - BEWO [nTPM]":"92.9","Cell RNA - BJ [nTPM]":"18.5","Cell RNA - BJ hTERT+ [nTPM]":"88.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"168.7","Cell RNA - Daudi [nTPM]":"48.1","Cell RNA - EFO-21 [nTPM]":"38.1","Cell RNA - fHDF\/TERT166 [nTPM]":"41.3","Cell RNA - GAMG [nTPM]":"92.2","Cell RNA - HaCaT [nTPM]":"2.9","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"30.3","Cell RNA - HBF TERT88 [nTPM]":"15.8","Cell RNA - HDLM-2 [nTPM]":"125.5","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"19.1","Cell RNA - HeLa [nTPM]":"9.9","Cell RNA - Hep G2 [nTPM]":"24.8","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"20.4","Cell RNA - HMC-1 [nTPM]":"63.0","Cell RNA - HSkMC [nTPM]":"51.7","Cell RNA - hTCEpi [nTPM]":"20.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.8","Cell RNA - hTERT-HME1 [nTPM]":"8.2","Cell RNA - hTERT-RPE1 [nTPM]":"37.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"16.0","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"140.8","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"19.6","Cell RNA - MOLT-4 [nTPM]":"51.9","Cell RNA - NB-4 [nTPM]":"44.1","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"2.8","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"35.5","Cell RNA - RT4 [nTPM]":"1.2","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"23.7","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"1.4","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"45.5","Cell RNA - U-138 MG [nTPM]":"89.4","Cell RNA - U-2 OS [nTPM]":"18.6","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"2.0","Cell RNA - U-266\/70 [nTPM]":"140.5","Cell RNA - U-266\/84 [nTPM]":"117.4","Cell RNA - U-698 [nTPM]":"46.2","Cell RNA - U-87 MG [nTPM]":"58.6","Cell RNA - U-937 [nTPM]":"38.8","Cell RNA - WM-115 [nTPM]":"58.8","Blood RNA - basophil [nTPM]":"159.7","Blood RNA - classical monocyte [nTPM]":"87.9","Blood RNA - eosinophil [nTPM]":"172.1","Blood RNA - gdT-cell [nTPM]":"137.3","Blood RNA - intermediate monocyte [nTPM]":"121.6","Blood RNA - MAIT T-cell [nTPM]":"117.0","Blood RNA - memory B-cell [nTPM]":"97.1","Blood RNA - memory CD4 T-cell [nTPM]":"99.7","Blood RNA - memory CD8 T-cell [nTPM]":"114.3","Blood RNA - myeloid DC [nTPM]":"90.0","Blood RNA - naive B-cell [nTPM]":"86.0","Blood RNA - naive CD4 T-cell [nTPM]":"76.2","Blood RNA - naive CD8 T-cell [nTPM]":"109.9","Blood RNA - neutrophil [nTPM]":"151.3","Blood RNA - NK-cell [nTPM]":"159.6","Blood RNA - non-classical monocyte [nTPM]":"139.0","Blood RNA - plasmacytoid DC [nTPM]":"102.9","Blood RNA - T-reg [nTPM]":"85.9","Blood RNA - total PBMC [nTPM]":"150.5","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"4.8","Brain RNA - cerebellum [nTPM]":"1.9","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"116.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"125.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"102.1","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"186.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"77.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"148.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"66.6","Single Cell Type RNA - Bipolar cells [nTPM]":"34.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"82.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"64.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"73.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"84.4","Single Cell Type RNA - Club cells [nTPM]":"105.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.9","Single Cell Type RNA - dendritic cells [nTPM]":"223.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"259.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"256.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"64.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.4","Single Cell Type RNA - Endothelial cells [nTPM]":"99.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"84.6","Single Cell Type RNA - Erythroid cells [nTPM]":"58.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"282.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"85.9","Single Cell Type RNA - Fibroblasts [nTPM]":"63.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"105.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"78.4","Single Cell Type RNA - granulocytes [nTPM]":"91.9","Single Cell Type RNA - Granulosa cells [nTPM]":"65.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.0","Single Cell Type RNA - Hepatocytes [nTPM]":"143.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"119.7","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"174.6","Single Cell Type RNA - Ionocytes [nTPM]":"83.4","Single Cell Type RNA - Kupffer cells [nTPM]":"124.3","Single Cell Type RNA - Langerhans cells [nTPM]":"128.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.2","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"131.9","Single Cell Type RNA - Melanocytes [nTPM]":"119.2","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"229.3","Single Cell Type RNA - Muller glia cells [nTPM]":"34.7","Single Cell Type RNA - NK-cells [nTPM]":"195.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"215.5","Single Cell Type RNA - Paneth cells [nTPM]":"172.4","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"194.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"130.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"283.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"113.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.1","Single Cell Type RNA - T-cells [nTPM]":"163.7","Single Cell Type RNA - Theca cells [nTPM]":"66.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"162.3","Single Cell Type RNA - Urothelial cells [nTPM]":"141.0"},{"Gene":"TBX1","Gene synonym":["CATCH22","VCF"],"Ensembl":"ENSG00000184058","Gene description":"T-box transcription factor 1","Uniprot":["O43435"],"Chromosome":"22","Position":"19756703-19783593","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"61.5","tongue":"36.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Late spermatids":"181.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"24.6","K-562":"121.6","NB-4":"28.6","TIME":"40.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029330"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nuclear bodies","Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA029330":"AB_2673002"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.90e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.0","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"8.0","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"7.4","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"1.8","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"2.6","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"7.7","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"7.6","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"61.5","Tissue RNA - skin 1 [nTPM]":"10.6","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"1.2","Tissue RNA - testis [nTPM]":"16.8","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"36.5","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"15.3","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"2.1","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"1.5","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"10.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"24.6","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"2.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"121.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"7.7","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"28.6","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"10.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"5.1","Cell RNA - THP-1 [nTPM]":"7.7","Cell RNA - TIME [nTPM]":"40.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"11.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"43.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.6","Single Cell Type RNA - Late spermatids [nTPM]":"181.9","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"TNFRSF13B","Gene synonym":["CD267","IGAD2","TACI"],"Ensembl":"ENSG00000240505","Gene description":"TNF receptor superfamily member 13B","Uniprot":["O14836"],"Chromosome":"17","Position":"16929816-16972118","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"intestine":"18.9","lymphoid tissue":"33.0","skeletal muscle":"62.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"117.3","Plasma cells":"143.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"41","RNA blood cell specific nTPM":{"memory B-cell":"130.9","naive B-cell":"51.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"59","RNA blood lineage specific nTPM":{"B-cells":"130.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Karpas-707":"167.2","RPMI-8226":"106.7","U-266\/70":"72.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030453"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA030453":"AB_10601700"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"8.9","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"4.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"17.3","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"62.9","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"18.9","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"33.0","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"167.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"106.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"72.6","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"13.5","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"130.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"51.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"117.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"143.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TNFRSF13C","Gene synonym":["BAFFR","CD268"],"Ensembl":"ENSG00000159958","Gene description":"TNF receptor superfamily member 13C","Uniprot":["Q96RJ3"],"Chromosome":"22","Position":"41922032-41926806","Protein class":["CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"33.8","lymphoid tissue":"58.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"B-cells":"194.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"36","RNA blood cell specific nTPM":{"memory B-cell":"22.5","naive B-cell":"29.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"B-cells":"29.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"REH":"21.0","U-698":"10.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003246","CAB008380"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB008380":"AB_590602","HPA003246":"AB_1078264"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.44e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"2.1","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"39.0","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"0.5","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.7","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"3.3","Tissue RNA - small intestine [nTPM]":"33.8","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"58.1","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"54.6","Tissue RNA - urinary bladder [nTPM]":"1.8","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"2.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"1.9","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"1.7","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"1.8","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"21.0","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"2.5","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"2.0","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"10.9","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"1.8","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"22.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"29.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"2.1","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"194.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"18.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TNFRSF4","Gene synonym":["ACT35","CD134","OX40","TXGP1L"],"Ensembl":"ENSG00000186827","Gene description":"TNF receptor superfamily member 4","Uniprot":["P43489"],"Chromosome":"1","Position":"1211340-1214153","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"10.3","lymphoid tissue":"13.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"112.3","Endothelial cells":"58.0","granulocytes":"67.4","Ionocytes":"40.7","Langerhans cells":"128.1","T-cells":"43.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"9.7","memory CD4 T-cell":"26.6","NK-cell":"14.7","T-reg":"35.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"granulocytes":"9.7","NK-cells":"14.7","T-cells":"35.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"MOLT-4":"6.2","NB-4":"12.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016128"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB016128":"AB_626897"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.50e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.52e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"6.7","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"3.3","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"1.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"10.3","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"4.1","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"3.7","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"13.3","Tissue RNA - stomach 1 [nTPM]":"2.6","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"1.7","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"6.2","Cell RNA - NB-4 [nTPM]":"12.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"9.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"26.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"14.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"35.3","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"112.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"11.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"25.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"58.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"67.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"128.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"9.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"18.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"26.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"43.6","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TYK2","Gene synonym":["JTK1"],"Ensembl":"ENSG00000105397","Gene description":"Tyrosine kinase 2","Uniprot":["P29597"],"Chromosome":"19","Position":"10350529-10380572","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"52.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NB-4":"206.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005157"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA005157":"AB_1858480"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.62e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.43e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.16e-4"},"Tissue RNA - adipose tissue [nTPM]":"53.0","Tissue RNA - adrenal gland [nTPM]":"60.5","Tissue RNA - amygdala [nTPM]":"69.9","Tissue RNA - appendix [nTPM]":"37.0","Tissue RNA - basal ganglia [nTPM]":"71.9","Tissue RNA - bone marrow [nTPM]":"82.6","Tissue RNA - breast [nTPM]":"52.5","Tissue RNA - cerebellum [nTPM]":"70.7","Tissue RNA - cerebral cortex [nTPM]":"82.3","Tissue RNA - cervix [nTPM]":"55.8","Tissue RNA - choroid plexus [nTPM]":"72.2","Tissue RNA - colon [nTPM]":"51.5","Tissue RNA - duodenum [nTPM]":"29.4","Tissue RNA - endometrium 1 [nTPM]":"44.8","Tissue RNA - epididymis [nTPM]":"22.6","Tissue RNA - esophagus [nTPM]":"46.2","Tissue RNA - fallopian tube [nTPM]":"49.0","Tissue RNA - gallbladder [nTPM]":"26.2","Tissue RNA - heart muscle [nTPM]":"65.0","Tissue RNA - hippocampal formation [nTPM]":"69.6","Tissue RNA - hypothalamus [nTPM]":"68.8","Tissue RNA - kidney [nTPM]":"77.3","Tissue RNA - liver [nTPM]":"111.2","Tissue RNA - lung [nTPM]":"72.6","Tissue RNA - lymph node [nTPM]":"51.5","Tissue RNA - medulla oblongata [nTPM]":"75.1","Tissue RNA - midbrain [nTPM]":"71.4","Tissue RNA - ovary [nTPM]":"56.4","Tissue RNA - pancreas [nTPM]":"65.1","Tissue RNA - parathyroid gland [nTPM]":"28.6","Tissue RNA - pituitary gland [nTPM]":"66.2","Tissue RNA - placenta [nTPM]":"20.1","Tissue RNA - pons [nTPM]":"71.5","Tissue RNA - prostate [nTPM]":"64.5","Tissue RNA - rectum [nTPM]":"25.7","Tissue RNA - retina [nTPM]":"25.2","Tissue RNA - salivary gland [nTPM]":"50.8","Tissue RNA - seminal vesicle [nTPM]":"20.6","Tissue RNA - skeletal muscle [nTPM]":"41.3","Tissue RNA - skin 1 [nTPM]":"51.1","Tissue RNA - small intestine [nTPM]":"73.9","Tissue RNA - smooth muscle [nTPM]":"23.5","Tissue RNA - spinal cord [nTPM]":"70.2","Tissue RNA - spleen [nTPM]":"140.8","Tissue RNA - stomach 1 [nTPM]":"54.6","Tissue RNA - testis [nTPM]":"16.6","Tissue RNA - thalamus [nTPM]":"71.8","Tissue RNA - thymus [nTPM]":"54.4","Tissue RNA - thyroid gland [nTPM]":"60.2","Tissue RNA - tongue [nTPM]":"33.7","Tissue RNA - tonsil [nTPM]":"51.8","Tissue RNA - urinary bladder [nTPM]":"49.3","Tissue RNA - vagina [nTPM]":"46.0","Tissue RNA - white matter [nTPM]":"76.4","Cell RNA - A-431 [nTPM]":"29.1","Cell RNA - A549 [nTPM]":"41.1","Cell RNA - AF22 [nTPM]":"24.1","Cell RNA - AN3-CA [nTPM]":"38.0","Cell RNA - ASC diff [nTPM]":"31.9","Cell RNA - ASC TERT1 [nTPM]":"44.2","Cell RNA - BEWO [nTPM]":"23.5","Cell RNA - BJ [nTPM]":"38.9","Cell RNA - BJ hTERT+ [nTPM]":"39.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.2","Cell RNA - CACO-2 [nTPM]":"31.5","Cell RNA - CAPAN-2 [nTPM]":"18.7","Cell RNA - Daudi [nTPM]":"44.5","Cell RNA - EFO-21 [nTPM]":"44.5","Cell RNA - fHDF\/TERT166 [nTPM]":"43.4","Cell RNA - GAMG [nTPM]":"32.8","Cell RNA - HaCaT [nTPM]":"28.4","Cell RNA - HAP1 [nTPM]":"29.4","Cell RNA - HBEC3-KT [nTPM]":"45.5","Cell RNA - HBF TERT88 [nTPM]":"24.2","Cell RNA - HDLM-2 [nTPM]":"78.0","Cell RNA - HEK 293 [nTPM]":"45.5","Cell RNA - HEL [nTPM]":"81.4","Cell RNA - HeLa [nTPM]":"90.5","Cell RNA - Hep G2 [nTPM]":"80.2","Cell RNA - HHSteC [nTPM]":"49.4","Cell RNA - HL-60 [nTPM]":"34.4","Cell RNA - HMC-1 [nTPM]":"89.4","Cell RNA - HSkMC [nTPM]":"43.2","Cell RNA - hTCEpi [nTPM]":"31.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"54.5","Cell RNA - hTERT-HME1 [nTPM]":"32.2","Cell RNA - hTERT-RPE1 [nTPM]":"29.9","Cell RNA - HUVEC TERT2 [nTPM]":"46.5","Cell RNA - JURKAT [nTPM]":"56.6","Cell RNA - K-562 [nTPM]":"35.0","Cell RNA - Karpas-707 [nTPM]":"116.1","Cell RNA - LHCN-M2 [nTPM]":"42.3","Cell RNA - MCF7 [nTPM]":"90.1","Cell RNA - MOLT-4 [nTPM]":"50.7","Cell RNA - NB-4 [nTPM]":"206.9","Cell RNA - NTERA-2 [nTPM]":"7.7","Cell RNA - OE19 [nTPM]":"28.4","Cell RNA - PC-3 [nTPM]":"71.8","Cell RNA - REH [nTPM]":"49.9","Cell RNA - RH-30 [nTPM]":"21.1","Cell RNA - RPMI-8226 [nTPM]":"45.1","Cell RNA - RPTEC TERT1 [nTPM]":"40.0","Cell RNA - RT4 [nTPM]":"90.1","Cell RNA - SCLC-21H [nTPM]":"22.4","Cell RNA - SH-SY5Y [nTPM]":"28.0","Cell RNA - SiHa [nTPM]":"37.6","Cell RNA - SK-BR-3 [nTPM]":"38.6","Cell RNA - SK-MEL-30 [nTPM]":"28.1","Cell RNA - SuSa [nTPM]":"18.4","Cell RNA - T-47d [nTPM]":"21.5","Cell RNA - THP-1 [nTPM]":"57.2","Cell RNA - TIME [nTPM]":"41.1","Cell RNA - U-138 MG [nTPM]":"61.7","Cell RNA - U-2 OS [nTPM]":"22.7","Cell RNA - U-2197 [nTPM]":"74.1","Cell RNA - U-251 MG [nTPM]":"45.9","Cell RNA - U-266\/70 [nTPM]":"97.2","Cell RNA - U-266\/84 [nTPM]":"81.4","Cell RNA - U-698 [nTPM]":"40.2","Cell RNA - U-87 MG [nTPM]":"32.4","Cell RNA - U-937 [nTPM]":"70.8","Cell RNA - WM-115 [nTPM]":"36.6","Blood RNA - basophil [nTPM]":"9.8","Blood RNA - classical monocyte [nTPM]":"20.8","Blood RNA - eosinophil [nTPM]":"27.2","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"15.2","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.6","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"23.5","Blood RNA - naive B-cell [nTPM]":"8.0","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"7.1","Blood RNA - neutrophil [nTPM]":"33.0","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"15.7","Blood RNA - plasmacytoid DC [nTPM]":"13.0","Blood RNA - T-reg [nTPM]":"10.1","Blood RNA - total PBMC [nTPM]":"13.0","Brain RNA - amygdala [nTPM]":"69.9","Brain RNA - basal ganglia [nTPM]":"71.9","Brain RNA - cerebellum [nTPM]":"70.7","Brain RNA - cerebral cortex [nTPM]":"82.3","Brain RNA - hippocampal formation [nTPM]":"69.6","Brain RNA - hypothalamus [nTPM]":"68.8","Brain RNA - medulla oblongata [nTPM]":"75.1","Brain RNA - midbrain [nTPM]":"71.4","Brain RNA - pons [nTPM]":"71.5","Brain RNA - spinal cord [nTPM]":"70.2","Brain RNA - thalamus [nTPM]":"71.8","Brain RNA - white matter [nTPM]":"76.4","Single Cell Type RNA - Adipocytes [nTPM]":"18.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.9","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"17.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"9.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"11.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - dendritic cells [nTPM]":"23.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"7.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.6","Single Cell Type RNA - Endothelial cells [nTPM]":"12.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.7","Single Cell Type RNA - Fibroblasts [nTPM]":"11.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.0","Single Cell Type RNA - granulocytes [nTPM]":"19.6","Single Cell Type RNA - Granulosa cells [nTPM]":"17.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"27.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.2","Single Cell Type RNA - Langerhans cells [nTPM]":"14.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.8","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"30.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"25.3","Single Cell Type RNA - Muller glia cells [nTPM]":"8.7","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.8","Single Cell Type RNA - Paneth cells [nTPM]":"12.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"19.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"19.4","Single Cell Type RNA - Theca cells [nTPM]":"13.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"UNC13D","Gene synonym":["Munc13-4"],"Ensembl":"ENSG00000092929","Gene description":"Unc-13 homolog D","Uniprot":["Q70J99"],"Chromosome":"17","Position":"75827225-75844552","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Exocytosis"],"Molecular function":null,"Disease involvement":["Familial hemophagocytic lymphohistiocytosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"58.9","lymphoid tissue":"66.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"68.3","Hofbauer cells":"58.5","NK-cells":"61.8","Pancreatic endocrine cells":"47.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"245.7","HeLa":"136.3","HMC-1":"245.9","SK-BR-3":"189.7"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"cerebellum":"5.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067117","HPA073525"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA067117":"AB_2685784","HPA073525":"AB_2686615"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.28e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.7","Tissue RNA - adrenal gland [nTPM]":"7.3","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"23.5","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"58.9","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"18.6","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"10.7","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"23.6","Tissue RNA - fallopian tube [nTPM]":"13.8","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"14.3","Tissue RNA - hippocampal formation [nTPM]":"5.0","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"6.6","Tissue RNA - liver [nTPM]":"12.6","Tissue RNA - lung [nTPM]":"38.1","Tissue RNA - lymph node [nTPM]":"25.9","Tissue RNA - medulla oblongata [nTPM]":"7.9","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"19.3","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"8.1","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"5.5","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"18.5","Tissue RNA - smooth muscle [nTPM]":"4.9","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"66.2","Tissue RNA - stomach 1 [nTPM]":"13.8","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"20.7","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"17.6","Tissue RNA - urinary bladder [nTPM]":"10.7","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"8.7","Cell RNA - A-431 [nTPM]":"44.0","Cell RNA - A549 [nTPM]":"18.7","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"47.6","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"41.4","Cell RNA - CAPAN-2 [nTPM]":"97.0","Cell RNA - Daudi [nTPM]":"3.4","Cell RNA - EFO-21 [nTPM]":"46.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"7.5","Cell RNA - HaCaT [nTPM]":"15.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"245.7","Cell RNA - HeLa [nTPM]":"136.3","Cell RNA - Hep G2 [nTPM]":"24.2","Cell RNA - HHSteC [nTPM]":"3.9","Cell RNA - HL-60 [nTPM]":"94.1","Cell RNA - HMC-1 [nTPM]":"245.9","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"2.3","Cell RNA - HUVEC TERT2 [nTPM]":"17.9","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"87.1","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"71.2","Cell RNA - MOLT-4 [nTPM]":"100.9","Cell RNA - NB-4 [nTPM]":"50.8","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"69.9","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"32.8","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"1.5","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"66.7","Cell RNA - SiHa [nTPM]":"19.2","Cell RNA - SK-BR-3 [nTPM]":"189.7","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"47.1","Cell RNA - THP-1 [nTPM]":"56.5","Cell RNA - TIME [nTPM]":"48.1","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"65.9","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"5.9","Cell RNA - U-698 [nTPM]":"4.0","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"31.3","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"59.1","Blood RNA - classical monocyte [nTPM]":"16.0","Blood RNA - eosinophil [nTPM]":"31.2","Blood RNA - gdT-cell [nTPM]":"19.3","Blood RNA - intermediate monocyte [nTPM]":"16.9","Blood RNA - MAIT T-cell [nTPM]":"17.4","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"11.4","Blood RNA - memory CD8 T-cell [nTPM]":"13.6","Blood RNA - myeloid DC [nTPM]":"12.3","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"8.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.9","Blood RNA - neutrophil [nTPM]":"40.1","Blood RNA - NK-cell [nTPM]":"14.7","Blood RNA - non-classical monocyte [nTPM]":"25.6","Blood RNA - plasmacytoid DC [nTPM]":"7.2","Blood RNA - T-reg [nTPM]":"10.8","Blood RNA - total PBMC [nTPM]":"18.1","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"5.0","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"7.9","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"8.7","Single Cell Type RNA - Adipocytes [nTPM]":"3.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.3","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"16.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"68.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"4.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.7","Single Cell Type RNA - dendritic cells [nTPM]":"27.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.3","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.6","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"45.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.6","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"21.6","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"22.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"22.5","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"61.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.3","Single Cell Type RNA - Paneth cells [nTPM]":"30.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"27.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.9","Single Cell Type RNA - T-cells [nTPM]":"30.9","Single Cell Type RNA - Theca cells [nTPM]":"2.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"UNG","Gene synonym":["DGU","HIGM4","UDG","UNG1","UNG2"],"Ensembl":"ENSG00000076248","Gene description":"Uracil DNA glycosylase","Uniprot":["P13051"],"Chromosome":"12","Position":"109097597-109110992","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"64.9","Spermatogonia":"74.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011605"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011605":"AB_778737"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.40e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.06e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"56.7","Tissue RNA - amygdala [nTPM]":"32.4","Tissue RNA - appendix [nTPM]":"14.7","Tissue RNA - basal ganglia [nTPM]":"32.4","Tissue RNA - bone marrow [nTPM]":"16.0","Tissue RNA - breast [nTPM]":"23.1","Tissue RNA - cerebellum [nTPM]":"30.1","Tissue RNA - cerebral cortex [nTPM]":"34.8","Tissue RNA - cervix [nTPM]":"16.6","Tissue RNA - choroid plexus [nTPM]":"27.7","Tissue RNA - colon [nTPM]":"28.0","Tissue RNA - duodenum [nTPM]":"17.1","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"12.7","Tissue RNA - esophagus [nTPM]":"29.7","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"10.4","Tissue RNA - heart muscle [nTPM]":"21.1","Tissue RNA - hippocampal formation [nTPM]":"29.2","Tissue RNA - hypothalamus [nTPM]":"34.9","Tissue RNA - kidney [nTPM]":"27.5","Tissue RNA - liver [nTPM]":"32.2","Tissue RNA - lung [nTPM]":"9.6","Tissue RNA - lymph node [nTPM]":"18.0","Tissue RNA - medulla oblongata [nTPM]":"32.2","Tissue RNA - midbrain [nTPM]":"31.4","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"12.4","Tissue RNA - parathyroid gland [nTPM]":"33.2","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"17.8","Tissue RNA - pons [nTPM]":"34.1","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"29.3","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"17.7","Tissue RNA - seminal vesicle [nTPM]":"17.6","Tissue RNA - skeletal muscle [nTPM]":"43.0","Tissue RNA - skin 1 [nTPM]":"32.7","Tissue RNA - small intestine [nTPM]":"18.8","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"31.6","Tissue RNA - spleen [nTPM]":"16.1","Tissue RNA - stomach 1 [nTPM]":"17.7","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"33.5","Tissue RNA - thymus [nTPM]":"22.8","Tissue RNA - thyroid gland [nTPM]":"22.2","Tissue RNA - tongue [nTPM]":"33.5","Tissue RNA - tonsil [nTPM]":"27.0","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"30.8","Cell RNA - A-431 [nTPM]":"77.1","Cell RNA - A549 [nTPM]":"77.5","Cell RNA - AF22 [nTPM]":"72.8","Cell RNA - AN3-CA [nTPM]":"66.6","Cell RNA - ASC diff [nTPM]":"118.6","Cell RNA - ASC TERT1 [nTPM]":"33.8","Cell RNA - BEWO [nTPM]":"69.5","Cell RNA - BJ [nTPM]":"44.4","Cell RNA - BJ hTERT+ [nTPM]":"30.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"52.3","Cell RNA - CACO-2 [nTPM]":"61.7","Cell RNA - CAPAN-2 [nTPM]":"51.6","Cell RNA - Daudi [nTPM]":"100.3","Cell RNA - EFO-21 [nTPM]":"65.1","Cell RNA - fHDF\/TERT166 [nTPM]":"40.2","Cell RNA - GAMG [nTPM]":"35.9","Cell RNA - HaCaT [nTPM]":"47.6","Cell RNA - HAP1 [nTPM]":"81.4","Cell RNA - HBEC3-KT [nTPM]":"46.0","Cell RNA - HBF TERT88 [nTPM]":"66.4","Cell RNA - HDLM-2 [nTPM]":"85.6","Cell RNA - HEK 293 [nTPM]":"150.9","Cell RNA - HEL [nTPM]":"98.1","Cell RNA - HeLa [nTPM]":"41.1","Cell RNA - Hep G2 [nTPM]":"105.5","Cell RNA - HHSteC [nTPM]":"17.7","Cell RNA - HL-60 [nTPM]":"147.6","Cell RNA - HMC-1 [nTPM]":"58.2","Cell RNA - HSkMC [nTPM]":"30.7","Cell RNA - hTCEpi [nTPM]":"41.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.0","Cell RNA - hTERT-HME1 [nTPM]":"18.3","Cell RNA - hTERT-RPE1 [nTPM]":"54.6","Cell RNA - HUVEC TERT2 [nTPM]":"50.4","Cell RNA - JURKAT [nTPM]":"117.8","Cell RNA - K-562 [nTPM]":"80.9","Cell RNA - Karpas-707 [nTPM]":"32.5","Cell RNA - LHCN-M2 [nTPM]":"47.0","Cell RNA - MCF7 [nTPM]":"96.2","Cell RNA - MOLT-4 [nTPM]":"136.8","Cell RNA - NB-4 [nTPM]":"173.6","Cell RNA - NTERA-2 [nTPM]":"130.0","Cell RNA - OE19 [nTPM]":"124.2","Cell RNA - PC-3 [nTPM]":"117.7","Cell RNA - REH [nTPM]":"123.9","Cell RNA - RH-30 [nTPM]":"109.8","Cell RNA - RPMI-8226 [nTPM]":"85.9","Cell RNA - RPTEC TERT1 [nTPM]":"43.4","Cell RNA - RT4 [nTPM]":"95.6","Cell RNA - SCLC-21H [nTPM]":"103.3","Cell RNA - SH-SY5Y [nTPM]":"57.4","Cell RNA - SiHa [nTPM]":"79.6","Cell RNA - SK-BR-3 [nTPM]":"67.8","Cell RNA - SK-MEL-30 [nTPM]":"39.5","Cell RNA - SuSa [nTPM]":"94.2","Cell RNA - T-47d [nTPM]":"126.2","Cell RNA - THP-1 [nTPM]":"68.2","Cell RNA - TIME [nTPM]":"26.0","Cell RNA - U-138 MG [nTPM]":"59.1","Cell RNA - U-2 OS [nTPM]":"52.7","Cell RNA - U-2197 [nTPM]":"39.3","Cell RNA - U-251 MG [nTPM]":"62.5","Cell RNA - U-266\/70 [nTPM]":"62.6","Cell RNA - U-266\/84 [nTPM]":"145.0","Cell RNA - U-698 [nTPM]":"190.5","Cell RNA - U-87 MG [nTPM]":"44.8","Cell RNA - U-937 [nTPM]":"97.7","Cell RNA - WM-115 [nTPM]":"73.8","Blood RNA - basophil [nTPM]":"12.9","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"22.4","Blood RNA - intermediate monocyte [nTPM]":"5.3","Blood RNA - MAIT T-cell [nTPM]":"31.6","Blood RNA - memory B-cell [nTPM]":"16.0","Blood RNA - memory CD4 T-cell [nTPM]":"25.5","Blood RNA - memory CD8 T-cell [nTPM]":"25.6","Blood RNA - myeloid DC [nTPM]":"6.8","Blood RNA - naive B-cell [nTPM]":"17.2","Blood RNA - naive CD4 T-cell [nTPM]":"16.4","Blood RNA - naive CD8 T-cell [nTPM]":"18.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"16.5","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"25.5","Blood RNA - total PBMC [nTPM]":"14.4","Brain RNA - amygdala [nTPM]":"32.4","Brain RNA - basal ganglia [nTPM]":"32.4","Brain RNA - cerebellum [nTPM]":"30.1","Brain RNA - cerebral cortex [nTPM]":"34.8","Brain RNA - hippocampal formation [nTPM]":"29.2","Brain RNA - hypothalamus [nTPM]":"34.9","Brain RNA - medulla oblongata [nTPM]":"32.2","Brain RNA - midbrain [nTPM]":"31.4","Brain RNA - pons [nTPM]":"34.1","Brain RNA - spinal cord [nTPM]":"31.6","Brain RNA - thalamus [nTPM]":"33.5","Brain RNA - white matter [nTPM]":"30.8","Single Cell Type RNA - Adipocytes [nTPM]":"26.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"42.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"64.9","Single Cell Type RNA - dendritic cells [nTPM]":"12.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"14.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.0","Single Cell Type RNA - Endothelial cells [nTPM]":"17.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"32.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.9","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"24.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"20.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.4","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"3.8","Single Cell Type RNA - Muller glia cells [nTPM]":"15.8","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"10.3","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"16.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.5","Single Cell Type RNA - Spermatocytes [nTPM]":"21.9","Single Cell Type RNA - Spermatogonia [nTPM]":"74.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.4","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"25.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"40.4","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"WAS","Gene synonym":["IMD2","THC","WASP","WASPA"],"Ensembl":"ENSG00000015285","Gene description":"WASP actin nucleation promoting factor","Uniprot":["P42768"],"Chromosome":"X","Position":"48676596-48691427","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"58.4","lymphoid tissue":"83.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"83.2","dendritic cells":"91.7","Hofbauer cells":"111.5","Kupffer cells":"110.7","Macrophages":"118.1","monocytes":"88.2","NK-cells":"84.5","Plasma cells":"57.8","T-cells":"99.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"37.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"37.4","monocytes":"9.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"76.5","HEL":"67.6","HMC-1":"157.0","MOLT-4":"70.8","NB-4":"75.7","RPMI-8226":"94.0","THP-1":"68.8","U-266\/70":"83.1","U-937":"87.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002022","CAB004290"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"600000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004290":"AB_628445","HPA002022":"AB_1080581"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.78e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"52.2","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"58.4","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"3.5","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"19.1","Tissue RNA - lymph node [nTPM]":"54.2","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"4.2","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"23.0","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"83.0","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"42.0","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"36.2","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"3.0","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"76.5","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"44.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"67.6","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"34.9","Cell RNA - HMC-1 [nTPM]":"157.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"40.3","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"45.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"7.6","Cell RNA - MOLT-4 [nTPM]":"70.8","Cell RNA - NB-4 [nTPM]":"75.7","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"61.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"94.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"68.8","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"83.1","Cell RNA - U-266\/84 [nTPM]":"43.6","Cell RNA - U-698 [nTPM]":"53.7","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"87.4","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"7.6","Blood RNA - eosinophil [nTPM]":"37.4","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"5.7","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"29.2","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"9.5","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"83.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"91.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"48.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"111.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"110.7","Single Cell Type RNA - Langerhans cells [nTPM]":"54.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"118.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"88.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"84.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"57.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"99.3","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"WIPF1","Gene synonym":["WASPIP","WIP"],"Ensembl":"ENSG00000115935","Gene description":"WAS\/WASL interacting protein family member 1","Uniprot":["O43516"],"Chromosome":"2","Position":"174559572-174682916","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"126.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"172.7","monocytes":"187.2","NK-cells":"245.1","Oligodendrocytes":"217.2","Plasma cells":"162.8","T-cells":"208.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"209.1","Karpas-707":"296.8","U-266\/70":"233.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003739","CAB009737","HPA070706"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"520000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB009737":"AB_2288577","HPA003739":"AB_1858783","HPA070706":"AB_2686300"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.14e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.0","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"14.2","Tissue RNA - appendix [nTPM]":"93.0","Tissue RNA - basal ganglia [nTPM]":"37.2","Tissue RNA - bone marrow [nTPM]":"56.8","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"36.1","Tissue RNA - cerebral cortex [nTPM]":"20.5","Tissue RNA - cervix [nTPM]":"30.6","Tissue RNA - choroid plexus [nTPM]":"11.1","Tissue RNA - colon [nTPM]":"26.0","Tissue RNA - duodenum [nTPM]":"18.2","Tissue RNA - endometrium 1 [nTPM]":"22.4","Tissue RNA - epididymis [nTPM]":"11.5","Tissue RNA - esophagus [nTPM]":"14.2","Tissue RNA - fallopian tube [nTPM]":"14.4","Tissue RNA - gallbladder [nTPM]":"34.8","Tissue RNA - heart muscle [nTPM]":"16.0","Tissue RNA - hippocampal formation [nTPM]":"14.9","Tissue RNA - hypothalamus [nTPM]":"28.8","Tissue RNA - kidney [nTPM]":"13.0","Tissue RNA - liver [nTPM]":"16.4","Tissue RNA - lung [nTPM]":"31.8","Tissue RNA - lymph node [nTPM]":"126.9","Tissue RNA - medulla oblongata [nTPM]":"46.2","Tissue RNA - midbrain [nTPM]":"38.6","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"7.3","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"4.8","Tissue RNA - placenta [nTPM]":"33.5","Tissue RNA - pons [nTPM]":"42.3","Tissue RNA - prostate [nTPM]":"14.9","Tissue RNA - rectum [nTPM]":"20.8","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"17.7","Tissue RNA - seminal vesicle [nTPM]":"23.0","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"32.5","Tissue RNA - smooth muscle [nTPM]":"29.1","Tissue RNA - spinal cord [nTPM]":"27.9","Tissue RNA - spleen [nTPM]":"89.7","Tissue RNA - stomach 1 [nTPM]":"21.8","Tissue RNA - testis [nTPM]":"4.7","Tissue RNA - thalamus [nTPM]":"35.1","Tissue RNA - thymus [nTPM]":"66.4","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"11.5","Tissue RNA - tonsil [nTPM]":"110.5","Tissue RNA - urinary bladder [nTPM]":"31.5","Tissue RNA - vagina [nTPM]":"17.0","Tissue RNA - white matter [nTPM]":"53.8","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"7.0","Cell RNA - AF22 [nTPM]":"16.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"40.4","Cell RNA - ASC TERT1 [nTPM]":"70.9","Cell RNA - BEWO [nTPM]":"16.9","Cell RNA - BJ [nTPM]":"31.1","Cell RNA - BJ hTERT+ [nTPM]":"26.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.7","Cell RNA - CACO-2 [nTPM]":"1.9","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"209.1","Cell RNA - EFO-21 [nTPM]":"9.2","Cell RNA - fHDF\/TERT166 [nTPM]":"47.0","Cell RNA - GAMG [nTPM]":"15.6","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"15.1","Cell RNA - HDLM-2 [nTPM]":"144.8","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"106.5","Cell RNA - HeLa [nTPM]":"26.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"15.1","Cell RNA - HL-60 [nTPM]":"94.9","Cell RNA - HMC-1 [nTPM]":"167.2","Cell RNA - HSkMC [nTPM]":"29.6","Cell RNA - hTCEpi [nTPM]":"5.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.7","Cell RNA - hTERT-HME1 [nTPM]":"2.6","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"25.0","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"3.3","Cell RNA - Karpas-707 [nTPM]":"296.8","Cell RNA - LHCN-M2 [nTPM]":"34.4","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"106.6","Cell RNA - NB-4 [nTPM]":"87.1","Cell RNA - NTERA-2 [nTPM]":"19.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"90.0","Cell RNA - RH-30 [nTPM]":"6.6","Cell RNA - RPMI-8226 [nTPM]":"37.9","Cell RNA - RPTEC TERT1 [nTPM]":"11.3","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"33.8","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"8.8","Cell RNA - SK-MEL-30 [nTPM]":"18.7","Cell RNA - SuSa [nTPM]":"30.4","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"46.8","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"41.0","Cell RNA - U-2 OS [nTPM]":"11.5","Cell RNA - U-2197 [nTPM]":"30.1","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"233.0","Cell RNA - U-266\/84 [nTPM]":"165.2","Cell RNA - U-698 [nTPM]":"113.7","Cell RNA - U-87 MG [nTPM]":"60.4","Cell RNA - U-937 [nTPM]":"64.7","Cell RNA - WM-115 [nTPM]":"111.7","Blood RNA - basophil [nTPM]":"41.5","Blood RNA - classical monocyte [nTPM]":"35.4","Blood RNA - eosinophil [nTPM]":"87.2","Blood RNA - gdT-cell [nTPM]":"71.6","Blood RNA - intermediate monocyte [nTPM]":"37.3","Blood RNA - MAIT T-cell [nTPM]":"59.4","Blood RNA - memory B-cell [nTPM]":"35.1","Blood RNA - memory CD4 T-cell [nTPM]":"47.6","Blood RNA - memory CD8 T-cell [nTPM]":"71.1","Blood RNA - myeloid DC [nTPM]":"26.1","Blood RNA - naive B-cell [nTPM]":"28.6","Blood RNA - naive CD4 T-cell [nTPM]":"38.0","Blood RNA - naive CD8 T-cell [nTPM]":"51.4","Blood RNA - neutrophil [nTPM]":"166.1","Blood RNA - NK-cell [nTPM]":"57.4","Blood RNA - non-classical monocyte [nTPM]":"43.7","Blood RNA - plasmacytoid DC [nTPM]":"11.2","Blood RNA - T-reg [nTPM]":"57.7","Blood RNA - total PBMC [nTPM]":"54.7","Brain RNA - amygdala [nTPM]":"14.2","Brain RNA - basal ganglia [nTPM]":"37.2","Brain RNA - cerebellum [nTPM]":"36.1","Brain RNA - cerebral cortex [nTPM]":"20.5","Brain RNA - hippocampal formation [nTPM]":"14.9","Brain RNA - hypothalamus [nTPM]":"28.8","Brain RNA - medulla oblongata [nTPM]":"46.2","Brain RNA - midbrain [nTPM]":"38.6","Brain RNA - pons [nTPM]":"42.3","Brain RNA - spinal cord [nTPM]":"27.9","Brain RNA - thalamus [nTPM]":"35.1","Brain RNA - white matter [nTPM]":"53.8","Single Cell Type RNA - Adipocytes [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.7","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"134.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"172.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"40.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.9","Single Cell Type RNA - Endothelial cells [nTPM]":"30.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"30.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"82.5","Single Cell Type RNA - Fibroblasts [nTPM]":"40.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"67.2","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.8","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"142.2","Single Cell Type RNA - Langerhans cells [nTPM]":"128.0","Single Cell Type RNA - Late spermatids [nTPM]":"96.9","Single Cell Type RNA - Leydig cells [nTPM]":"25.1","Single Cell Type RNA - Macrophages [nTPM]":"139.8","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"98.4","Single Cell Type RNA - monocytes [nTPM]":"187.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"245.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"120.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"162.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"208.1","Single Cell Type RNA - Theca cells [nTPM]":"8.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"XIAP","Gene synonym":["API3","BIRC4","hILP","ILP-1"],"Ensembl":"ENSG00000101966","Gene description":"X-linked inhibitor of apoptosis","Uniprot":["P98170"],"Chromosome":"X","Position":"123859724-123913976","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Protease inhibitor","Thiol protease inhibitor","Transferase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009203","HPA042428"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB009203":"AB_2257167","HPA042428":"AB_2677993"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.21e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.2","Tissue RNA - adrenal gland [nTPM]":"7.7","Tissue RNA - amygdala [nTPM]":"6.5","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"7.5","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"9.7","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"12.9","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"10.1","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"11.5","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"8.6","Tissue RNA - heart muscle [nTPM]":"7.8","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"8.2","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"12.1","Tissue RNA - lung [nTPM]":"8.5","Tissue RNA - lymph node [nTPM]":"10.4","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"7.5","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"18.4","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"8.6","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"21.4","Tissue RNA - salivary gland [nTPM]":"8.6","Tissue RNA - seminal vesicle [nTPM]":"7.4","Tissue RNA - skeletal muscle [nTPM]":"10.3","Tissue RNA - skin 1 [nTPM]":"8.8","Tissue RNA - small intestine [nTPM]":"10.1","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"10.4","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"8.9","Tissue RNA - thyroid gland [nTPM]":"14.9","Tissue RNA - tongue [nTPM]":"11.9","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"15.8","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"10.2","Cell RNA - AN3-CA [nTPM]":"8.8","Cell RNA - ASC diff [nTPM]":"11.8","Cell RNA - ASC TERT1 [nTPM]":"15.0","Cell RNA - BEWO [nTPM]":"13.3","Cell RNA - BJ [nTPM]":"16.9","Cell RNA - BJ hTERT+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.7","Cell RNA - CACO-2 [nTPM]":"5.9","Cell RNA - CAPAN-2 [nTPM]":"17.9","Cell RNA - Daudi [nTPM]":"14.7","Cell RNA - EFO-21 [nTPM]":"24.3","Cell RNA - fHDF\/TERT166 [nTPM]":"14.4","Cell RNA - GAMG [nTPM]":"17.1","Cell RNA - HaCaT [nTPM]":"5.6","Cell RNA - HAP1 [nTPM]":"15.3","Cell RNA - HBEC3-KT [nTPM]":"10.5","Cell RNA - HBF TERT88 [nTPM]":"16.3","Cell RNA - HDLM-2 [nTPM]":"15.5","Cell RNA - HEK 293 [nTPM]":"8.3","Cell RNA - HEL [nTPM]":"9.9","Cell RNA - HeLa [nTPM]":"11.1","Cell RNA - Hep G2 [nTPM]":"9.2","Cell RNA - HHSteC [nTPM]":"14.9","Cell RNA - HL-60 [nTPM]":"18.1","Cell RNA - HMC-1 [nTPM]":"19.7","Cell RNA - HSkMC [nTPM]":"10.4","Cell RNA - hTCEpi [nTPM]":"16.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.9","Cell RNA - hTERT-HME1 [nTPM]":"19.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.2","Cell RNA - HUVEC TERT2 [nTPM]":"12.7","Cell RNA - JURKAT [nTPM]":"10.8","Cell RNA - K-562 [nTPM]":"15.9","Cell RNA - Karpas-707 [nTPM]":"16.4","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"16.5","Cell RNA - MOLT-4 [nTPM]":"10.2","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"8.4","Cell RNA - OE19 [nTPM]":"15.6","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"10.8","Cell RNA - RH-30 [nTPM]":"11.9","Cell RNA - RPMI-8226 [nTPM]":"15.6","Cell RNA - RPTEC TERT1 [nTPM]":"13.4","Cell RNA - RT4 [nTPM]":"22.6","Cell RNA - SCLC-21H [nTPM]":"6.8","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"22.9","Cell RNA - SK-BR-3 [nTPM]":"13.0","Cell RNA - SK-MEL-30 [nTPM]":"13.5","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"8.7","Cell RNA - TIME [nTPM]":"15.7","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"6.0","Cell RNA - U-2197 [nTPM]":"27.0","Cell RNA - U-251 MG [nTPM]":"18.9","Cell RNA - U-266\/70 [nTPM]":"13.8","Cell RNA - U-266\/84 [nTPM]":"14.9","Cell RNA - U-698 [nTPM]":"15.8","Cell RNA - U-87 MG [nTPM]":"18.3","Cell RNA - U-937 [nTPM]":"12.7","Cell RNA - WM-115 [nTPM]":"11.5","Blood RNA - basophil [nTPM]":"9.3","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"3.6","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"2.9","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"6.5","Brain RNA - basal ganglia [nTPM]":"7.5","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"8.2","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"50.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"91.6","Single Cell Type RNA - Astrocytes [nTPM]":"26.4","Single Cell Type RNA - B-cells [nTPM]":"42.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"72.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"55.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"95.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.9","Single Cell Type RNA - dendritic cells [nTPM]":"41.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"122.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"36.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.9","Single Cell Type RNA - Endothelial cells [nTPM]":"55.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.4","Single Cell Type RNA - Erythroid cells [nTPM]":"23.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"54.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.0","Single Cell Type RNA - Fibroblasts [nTPM]":"38.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.4","Single Cell Type RNA - granulocytes [nTPM]":"60.7","Single Cell Type RNA - Granulosa cells [nTPM]":"30.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"64.2","Single Cell Type RNA - Hepatocytes [nTPM]":"85.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.0","Single Cell Type RNA - Horizontal cells [nTPM]":"75.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"34.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"62.2","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"43.6","Single Cell Type RNA - Langerhans cells [nTPM]":"33.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"42.6","Single Cell Type RNA - Macrophages [nTPM]":"44.2","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"45.8","Single Cell Type RNA - Muller glia cells [nTPM]":"45.8","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"65.4","Single Cell Type RNA - Paneth cells [nTPM]":"53.5","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"39.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"59.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"59.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"133.7","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.9","Single Cell Type RNA - Spermatocytes [nTPM]":"15.2","Single Cell Type RNA - Spermatogonia [nTPM]":"21.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"40.8","Single Cell Type RNA - Theca cells [nTPM]":"30.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"48.0","Single Cell Type RNA - Urothelial cells [nTPM]":"68.1"},{"Gene":"ZAP70","Gene synonym":["SRK","STD","ZAP-70"],"Ensembl":"ENSG00000115085","Gene description":"Zeta chain of T cell receptor associated protein kinase 70","Uniprot":["P43403"],"Chromosome":"2","Position":"97713576-97739862","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Disease variant","SCID"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"24.8","lymphoid tissue":"79.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"dendritic cells":"101.0","NK-cells":"155.5","T-cells":"105.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"41","RNA blood cell specific nTPM":{"gdT-cell":"137.4","MAIT T-cell":"93.2","memory CD4 T-cell":"71.7","memory CD8 T-cell":"108.3","naive CD4 T-cell":"50.8","naive CD8 T-cell":"79.8","NK-cell":"112.2","T-reg":"80.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"NK-cells":"112.2","T-cells":"137.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"JURKAT":"121.0","MOLT-4":"183.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002625","HPA003134"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002625":null,"HPA003134":"AB_1080629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.89e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.66e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.3","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"28.0","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"24.8","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"1.7","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"8.7","Tissue RNA - lymph node [nTPM]":"57.0","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.3","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"18.5","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"35.5","Tissue RNA - stomach 1 [nTPM]":"6.7","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"79.9","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"17.7","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"121.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"183.4","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"7.2","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"9.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"14.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"137.4","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"93.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"71.7","Blood RNA - memory CD8 T-cell [nTPM]":"108.3","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"50.8","Blood RNA - naive CD8 T-cell [nTPM]":"79.8","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"112.2","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"80.1","Blood RNA - total PBMC [nTPM]":"64.2","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"101.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"155.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"28.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"105.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"ZBTB24","Gene synonym":["BIF1","KIAA0441","PATZ2","ZNF450"],"Ensembl":"ENSG00000112365","Gene description":"Zinc finger and BTB domain containing 24","Uniprot":["O43167"],"Chromosome":"6","Position":"109462594-109483219","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"65.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017872","HPA049003"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytokinetic bridge","Centrosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge","Centrosome"],"Antibody RRID":{"HPA017872":"AB_2669673","HPA049003":"AB_2680596"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.15e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"3.5","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"8.7","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"3.2","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"3.8","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"4.4","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"4.7","Tissue RNA - small intestine [nTPM]":"3.7","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"6.9","Tissue RNA - thyroid gland [nTPM]":"4.9","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"7.3","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"4.3","Cell RNA - AN3-CA [nTPM]":"10.8","Cell RNA - ASC diff [nTPM]":"6.8","Cell RNA - ASC TERT1 [nTPM]":"6.9","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"5.3","Cell RNA - BJ hTERT+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.4","Cell RNA - CACO-2 [nTPM]":"6.7","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"20.0","Cell RNA - EFO-21 [nTPM]":"6.7","Cell RNA - fHDF\/TERT166 [nTPM]":"6.7","Cell RNA - GAMG [nTPM]":"7.8","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"8.3","Cell RNA - HBF TERT88 [nTPM]":"9.8","Cell RNA - HDLM-2 [nTPM]":"12.4","Cell RNA - HEK 293 [nTPM]":"10.7","Cell RNA - HEL [nTPM]":"16.2","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"5.1","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"7.0","Cell RNA - hTCEpi [nTPM]":"6.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.6","Cell RNA - hTERT-HME1 [nTPM]":"11.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.6","Cell RNA - HUVEC TERT2 [nTPM]":"5.5","Cell RNA - JURKAT [nTPM]":"9.3","Cell RNA - K-562 [nTPM]":"13.8","Cell RNA - Karpas-707 [nTPM]":"11.0","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"8.0","Cell RNA - MOLT-4 [nTPM]":"19.2","Cell RNA - NB-4 [nTPM]":"9.0","Cell RNA - NTERA-2 [nTPM]":"10.7","Cell RNA - OE19 [nTPM]":"4.7","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"11.9","Cell RNA - RH-30 [nTPM]":"6.1","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"8.0","Cell RNA - RT4 [nTPM]":"8.0","Cell RNA - SCLC-21H [nTPM]":"7.3","Cell RNA - SH-SY5Y [nTPM]":"6.4","Cell RNA - SiHa [nTPM]":"6.8","Cell RNA - SK-BR-3 [nTPM]":"7.1","Cell RNA - SK-MEL-30 [nTPM]":"16.9","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"5.0","Cell RNA - THP-1 [nTPM]":"14.5","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"5.3","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"4.4","Cell RNA - U-251 MG [nTPM]":"11.5","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"4.4","Cell RNA - U-698 [nTPM]":"20.2","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"10.4","Cell RNA - WM-115 [nTPM]":"9.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"32.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"21.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - dendritic cells [nTPM]":"16.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.3","Single Cell Type RNA - Endothelial cells [nTPM]":"6.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.9","Single Cell Type RNA - Fibroblasts [nTPM]":"8.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.6","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"12.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"10.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"20.5","Single Cell Type RNA - Muller glia cells [nTPM]":"10.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"5.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"16.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.4","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"27.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - T-cells [nTPM]":"17.8","Single Cell Type RNA - Theca cells [nTPM]":"15.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"7.3"},{"Gene":"ZNF341","Gene synonym":["dJ553F4.3"],"Ensembl":"ENSG00000131061","Gene description":"Zinc finger protein 341","Uniprot":["Q9BYN7"],"Chromosome":"20","Position":"33731657-33792269","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"11.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023240","HPA024607","HPA067108"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Vesicles"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA023240":"AB_1859207","HPA024607":"AB_1859208","HPA067108":"AB_2685780"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.87e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"6.4","Cell RNA - AF22 [nTPM]":"2.2","Cell RNA - AN3-CA [nTPM]":"4.7","Cell RNA - ASC diff [nTPM]":"2.1","Cell RNA - ASC TERT1 [nTPM]":"1.7","Cell RNA - BEWO [nTPM]":"9.5","Cell RNA - BJ [nTPM]":"2.3","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"5.4","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"2.2","Cell RNA - HaCaT [nTPM]":"3.7","Cell RNA - HAP1 [nTPM]":"2.4","Cell RNA - HBEC3-KT [nTPM]":"4.1","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"3.6","Cell RNA - HeLa [nTPM]":"3.6","Cell RNA - Hep G2 [nTPM]":"3.7","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"2.1","Cell RNA - HMC-1 [nTPM]":"4.3","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"1.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.3","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"1.7","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"2.9","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"1.6","Cell RNA - NTERA-2 [nTPM]":"3.0","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"2.4","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.3","Cell RNA - RT4 [nTPM]":"5.2","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"6.1","Cell RNA - SK-BR-3 [nTPM]":"5.6","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"5.0","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"3.4","Cell RNA - U-2 OS [nTPM]":"1.4","Cell RNA - U-2197 [nTPM]":"2.5","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"1.3","Cell RNA - U-266\/84 [nTPM]":"1.9","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"3.3","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"1.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.3","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"1.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"}]